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Page 1: Referências Bibliográficas - ULisboarepositorio.ul.pt/.../10451/1701/...Bibliograficas.pdf · Referências Bibliográficas 225 retention of astatine-, bismuth-, and lead-radiolabeled

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Referências Bibliográficas

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Referências Bibliográficas

222

1. Zutphen S.V., Targeting Platinum Compounds Synthesis and Biological Evaluation, F&N

Boekservice / Eigen Beheer, 2005.

2. Liu S., The role of coordination chemistry in the development of target-specific

radiopharmaceuticals, Chem. Soc. Rev. 33, 445-461, 2004.

3. Abram U., Alberto R., Technetium and Rhenium – Coordination Chemistry and Nuclear

Medical Aplications, J. Braz. Chem. Soc., 8, 1486-1500, 2006.

4. Alberts B., Bray D., Hopkin K., Johnson A., Lewis J., Raff M., Roberts K., Walter P.,

Essential cell biology, Garland Science, 2ª ed., 698 – 736, 2004.

5. Bartsch R., Fromm S., Rudas M., Wenzel C., Harbauer S., Roessler K., Kitz K., Steger G.G.,

Weitmann H.D., Poetter R., Zielinski C.C., Dieckmann K., Intensified local treatment and

systemic therapy significantly increase survival in patients with brain metastases from advanced

breast cancer – a retrospective analysis, Radiot. Oncol., 80, 313-317, 2006.

6. Buchegger F., Perillo-Adamer F., Dupertuis Y.M., Delaloye A.B., Auger Radiation Target

into DNA: a Therapy Perspective, Eur. J. Nucl. Med. Mol. Imag., 33: 1352-1363, 2006.

7. Neal M.J., Medical Pharmacology at a Glance, 3ª ed., Blackwell Science Ltd, 1997.

8. Silverman R.B., The organic chemistry of drug design and drug action, Academic Pres Inc.,

USA, 1992.

9. Dyson P.J., Sava G., Metal-based antitumor drugs in the post genomic era, Dalton Trans.,

1929-1933, 2006.

10. Zubay G., Biochemistry, 3th Ed, Wm. C. Brown Communication, Inc., U.S.A., 1993.

11. Kostakis I. K., Magiatis P., Pouli N., Marakos P., Skaltsounis A.-L., Pratsinis H., Léonce S.,

Pierré A., Design, synthesis, and antiproliferative activity of some new pyrazole-fused amino

derivatives of pyranoxanthenone, pyranothioxanthenone, and pyranoacridone ring systems: a

new class of cytotoxic agents, J. Med. Chem., 45(12), 2599-2609, 2002

Page 3: Referências Bibliográficas - ULisboarepositorio.ul.pt/.../10451/1701/...Bibliograficas.pdf · Referências Bibliográficas 225 retention of astatine-, bismuth-, and lead-radiolabeled

Referências Bibliográficas

223

12. Rodger A., Blagbrough I.S., Adlam G., Carpenter M.L., DNA binding of spermine

derivative. Spectroscopic study of anthracene-9-carbonyl-N1-spermine with poly [d(G-C)·d(G-

C)] and poly [d(A-T)·d(A-T)], Biopol., 34(12), 1583-1593,1994.

13. Modukuru N.K., Snow K.J., Scott Perrin Jr. B., Bhambhani A., Duff M., Kumar C.V.,

Tuning the DNA binding modes of an anthracene derivative with salt, J. Photochem. Photobiol.

A: Chem., 177, 43-54, 2006.

14. Langer M., Kratz F., Rothen-Rutishauser B., Wunderli-Allenspach H., Beck-Sickinger A.G.,

Novel peptide conjugate for tumor-specific chemotherapy, J. Med. Chem., 44, 1341-1348, 2001.

15. Berg S.L., Status of new antrapyrazole and pyrazoloacridine derivatives, Crit. Rev.

Oncol./Hematol., 22, 79-87, 1996.

16. Zhang L., Meler. E., Watson E. J., Gibson E. P., Reversal of the regioselectivity of

anthrapyrazole formation. A new synthesis of Losoxantrone (DUP941), Tetrahedron Let.,

35(22), 3675-3678, 1994.

17. Sissi C., Manlio P. Antitumor Potential of Aza-bioisosterism in Anthracenedione-based

Drugs, Cur. Top. Med. Chem., 4 (2), 219-230, 2004.

18. Martins E.T., Baruah H., Kramarczyk J., Saluta G., Day C.S., Kucera G.L., Bierbach U.,

Design, Synthesis, and Biological Activity of a Novel Non-Cisplatin-type Platinum-Acridine

Pharmacophore, J. Med. Chem., 44, 4492-4496, 2001.

19. Luedtke N.W., Hwang J.S., Nava E., Gut Dalia, Kol M., Tor Y., The DNA and RNA

specificity of eilatin Ru(II) complexes as compared to eilatin and ethidium bromide, Nucleic

Acid Res., 31(19), 5732-5740, 2003.

20. Vock C. A., Ang W. H., Scolaro C., Phillips A. D., Lagopoulos L., Juillerat-Jeanneret L.,

Sava G., Scopelliti R., Dyson P. J., Development of ruthenium antitumor drugs that overcome

multidrug resistance mechanisms, J. Med. Chem., 50(9), 2166-75, 2007.

Page 4: Referências Bibliográficas - ULisboarepositorio.ul.pt/.../10451/1701/...Bibliograficas.pdf · Referências Bibliográficas 225 retention of astatine-, bismuth-, and lead-radiolabeled

Referências Bibliográficas

224

21. Hambley T.W. Developing new metal-based therapeutics: challenges and opportunities,

Dalton Trans., DOI: 10.1039/b706075k, 2007

22. Kowalsky R.J., Falen S.W, Radiopharmaceuticals in Nuclear Pharmacy and Nuclear

Medicine, 2nd, American Pharmacists Association, 2004.

23. Reichert D. E., Lewis J. S, Anderson C. J, Metal complexes as diagnostic tools, Coordinat.

Chem. Rev., 184, 3-66, 1999.

24. Schibli R., Schubiger P.A., Current use and future potential of organometallic

radiopharmaceuticals, Eur. J. Nucl. Med., 29(11), 1529-1542, 2002.

25. Langer M., Beck-Sickinger A.G., Peptides as carrier for tumor diagnosis and treatment,

Curr. Med. Chem. – Anti-Cancer Agents, 1, 71-93, 2001.

26. Unak P., Targeted Tumor Radiotherapy, Braz. Arch. Biol. Technol., 45, 97-110, 2002.

27. Saha G. B., Fundamentals of Nuclear Pharmacy, 5th Ed, Springer, 2004.

28. http://us.myoview.com/tech/diagtest.html, 10/06/2007

29. Stepanek J., Larsson B., Weinreich R., Auger-electron spectra of radionuclides for therapy

and diagnostics, Acta Oncol., 35(7), 863-868, 1996.

30. Kassis A.I., Adelstein S.J., Radiobiologic principles in radionuclide therapy, J. Nucl. Med.,

46(1), 4S-12S, 2005.

31. Gardin I., Faraggi M., Le Guludec D., Bok B., Cell irradiation caused by diagnostic nuclear

medicine procedures: dose heterogeneity and biological consequences, Eur. J. Nucl. Med., 26,

1617-1626, 1999.

32. Yao Z., Garmestani K., Wong K.J., Park L.S., Dadachova E., Yordanov A., Waldmann

T.A., Eckelman W.C., Paik C.H., Carrasquillo J.A., Comparative cellular catabolism and

Page 5: Referências Bibliográficas - ULisboarepositorio.ul.pt/.../10451/1701/...Bibliograficas.pdf · Referências Bibliográficas 225 retention of astatine-, bismuth-, and lead-radiolabeled

Referências Bibliográficas

225

retention of astatine-, bismuth-, and lead-radiolabeled internalizing monoclonal antibody,

J.Nucl.Med., 42(10), 1538-1544, 2001.

33. Howell R.W., Narra V.R., Sastry K.S., Rao D.V., On the equivalent dose for Auger electron

emitters, Radiat Res., 134(1), 71-78, 1993.

34. Boswell C. A., Brechbiel M. W., Invited Perspective: Auger Electrons: Lethal, Low Energy,

and Coming Soon to a Tumor Cell Nucleus Near You, J. Nucl. Med., 46(12), 1946-1947, 2005.

35. http://www.chm.bris.ac.uk/webprojects2002/wrigglesworth/history.htm, 12/04/2007

36. Larson S. M., Krenning E. P., A pragmatic perspective on molecular targeted radionuclide

therapy, J. Nucl. Med., 46(1), 1S-3S, 2005.

37. Brans B., Bodei L., Giammarile F., Linden O., Luster M., Oyen W.J.G., Tennvall J.,

Clinical radionuclide therapy dosimetry: the quest for “Holy Gray”, Eur. J. Med Mol Imag., 34,

772-786, 2007.

38. Boswell C.A., Brechbiel M.W. Development of radioimmunotherapeutic and diagnostic

antibodies: an inside-out view, Nucl. Med. Biol., 34, 757-778, 2007.

39. Essen M.V., Krenning E.P., Jong M.D., Valkema R., Kwekkeboom D.J., Peptide Receptor

Radionuclide Therapy with radiolabelled somatostatin analogues in patients with somatostatin

receptor positive tumours, Acta Oncolog., 46, 723-734, 2007.

40. Panyutin I.G., Neumann R.D., The potential for gene-targeted radiation therapy of cancers,

Trends in Biotec., 23, 492-496, 2005.

41. Ftacnikova S., Bohm R., Monte Carlo calculations of energy deposition in DNA for auger

emitter, Rad. Prot. Dos., 92(4), 269-278, 2000.

42. Faraggi M., Gardin I., Labriolle-Vaylet C, Moretti J. L., Bok B. D., The Influence of Tracer

Localization on the Electron Dose Rate Delivered to the Cell Nucleus, J. Nucl. Med., 35(1),

113-119, 1994.

Page 6: Referências Bibliográficas - ULisboarepositorio.ul.pt/.../10451/1701/...Bibliograficas.pdf · Referências Bibliográficas 225 retention of astatine-, bismuth-, and lead-radiolabeled

Referências Bibliográficas

226

43. Kassis A. I., Cancer therapy with auger electrons: are we almost there?, J. Nucl. Med.,

44(9), 1479-1481, 2003.

44. Pouget J.P., Mather S.J., General aspects of cellular response to low- and high-LET

radiation, Eur. J. Nucl. Med., 28, 541-561, 2001.

45. Thierens H.M., Monsieurs M.A., Brans B., Driessche T.V., Christiaens I., Dierckx R.A,

Dosimetry from organ to celular dimensions, Comp. Med. Imag. Graph., 25, 187-193, 2001.

46. Behr T.M., Béhe M., Lohr M., Sgouros G., Angerstein C., Wehrmann E., Nebendahl K.,

Becker W., Therapeutic advantages of Auger electron- over β-emitting radiometals or

radioiodine when conjugated to internalizing antibodies, Eur. J. Nucl. Med., 27, 753-765, 2000.

47. Karamychev V. N., Reed M. W., Neumann R. D., Panyutin I. G., Distribution of DNA

strand breaks produced by iodine-123 and indium-111 in synthetic oligodeoxynucleotides, Acta

Oncolog., 39, 687-692, 2000.

48. Meyers M.O., Anthony L.B., McCarthy K.E., Drouant G., Maloney T.J., Espanan G.D.,

High-dose indium 111In pentetreotide radiotherapy for metastatic atypical carcinoid tumor,

South. Med. J., 93(8), 809-811, 2000.

49. Kwekkeboom D., Krenning E.P., Jong M., Peptide receptor imaging and therapy, J. Nucl.

Med., 41(10), 1704-1713, 2000.

50. Mariani G., Bodei L., Adelstein S.J., Kassis A., Invited commentary: Emerging roles for

radiometabolic therapy of tumors based on auger electron emission, J. Nucl. Med., 41, 1519-

1521, 2000.

51. Escriou V., Carrière M., Scherman D., Wils P., NLS bioconjugates for targeting therapeutic

genes to the nucleus, Adv. Drug Deliv. Rev. 55, 295-306, 2003.

Page 7: Referências Bibliográficas - ULisboarepositorio.ul.pt/.../10451/1701/...Bibliograficas.pdf · Referências Bibliográficas 225 retention of astatine-, bismuth-, and lead-radiolabeled

Referências Bibliográficas

227

52. Ginj M., Maecke H.R., Synthesis of trifunctional somatostatin based derivatives for

improved cellular and subcellular uptake, Tetrahedron Let., 46, 2821-2824, 2005.

53. Ginj M., Hinni K., Tschum S., Schulz S., Maecke H.R., Trifunctional somatostatin-based

derivatives designed for targeted radiotherapy using auger electron emitters, J Nucl Med, 46,

2097-2103, 2005.

54. Pouton C.W., Wagstaff K.M., Roth D.M., Moseley G.W., Jans D.A., Targeted delivery to

the nucleus, Adv. Drug Deliv., 59, 698-717, 2007

55. Constantini D.L., Chan C., Cai Z., Vallis K.A., Reilly R.M., 111In-labeled Trastuzumab

(Herceptin) modified with nuclear localization sequences (NLS): an auger electron-emitting

radiotherapeutic agent for HER2/neu-amplified breast cancer, J. Nucl. Med., 48, 8, 1357-1368,

2007.

56. Haefliger P., Agorastos N., Renard A., Giambonini-Brugnoli G., Marty C., Alberto R., Cell

uptake and radiotoxicity studies of an nuclear localization-signal peptide-intercalator conjugate

labeled with [99mTc(CO)3]+, Bioconjugate Chem., 16(3), 582-587, 2005.

57. Chen P., Cameron R., Wang J., Vallis K. A., Reilly Raymond M., Antitumor Effects and

Normal Tissue Toxicity of 111In-Labeled Epidermal Growth Factor Administered to Athymic

Mice Bearing Epidermal Growth Factor Receptor-Positive Human Breast Cancer Xenografs, J.

Nucl. Med., 44(9), 1469-1478, 2003.

58. Reilly R.M., Scollard D.A., Wang J., Mondal H., Chen P., Henderson L.A., Bowen B.M.,

Vallis K.A., A Kit formulated under good manufacturing practices for labeling human

epidermal growth factor with 111In for radiotherapeutic applications, J. Nucl. Med., 45(4), 701-

708, 2004.

59. Reilly R.M., Chen P., Wang J., Scollard D., Cameron R., Vallis K.A., Preclinical

pharmacokinetic, biodistribution, toxicology, and dosimetry studies of 111In-DTPA-human

epidermal growth factor: an auger electron-emitting radiotherapeutic agent for epidermal growth

factor receptor-positive breast cancer, J. Nucl. Med., 47(6), 1023-1031, 2006.

Page 8: Referências Bibliográficas - ULisboarepositorio.ul.pt/.../10451/1701/...Bibliograficas.pdf · Referências Bibliográficas 225 retention of astatine-, bismuth-, and lead-radiolabeled

Referências Bibliográficas

228

60. Haefliger P., Agorastos N., Spingler B., Georgiev O., Viola G., Alberto R., Induction of

DNA-double-strand breaks by auger electrons from 99mTc complexes with DNA-binding

ligands, ChemBioChem., 6, 412-421, 2005

61. Dilworth J.R., Parrott S.J., The biomedical chemistry of technetium and rhenium, Chem.

Soc. Rev., 27, 43-55, 1998.

62. Alberto R., Schibli R., Egli A., Schubiger P.A., Abram U, Kaden T.A., A novel

organometallic aqua-complex of technetium for the labeling of biomolecules: synthesis of

[99mTc(OH2)(CO)3]+ from [99mTcO4]- in aqueous solution and its reaction with bifunctional

ligands, J. Am. Chem. Soc., 120, 7987-7988, 1998.

63. Alberto R., Ortner K., Wheatley N., Schibli R., Schubiger P.A., Synthesis and properties of

boranecarbonate: a conveniente in sito CO source for the aqueous preparation of

[99mTc(CO)3(H2O)]+, J. Am. Chem. Soc., 123, 3135-3136, 2001.

64. Banerjee S. R., Levadala M. K., Lazarova N., Wei L., Valliant J.F., Stephenson K.A.,

Babich J. W., Maresca K. P., Zubieta J., Bifunctional Single Amino Acid Chelates for Labeling

of Biomolecules with the {Tc(CO)3}+ and {Re(CO)3}+ Cores. Crystal and Molecular Structures

of [ReBr(CO)3(H2NCH2C5H4N)],

[Re(CO)3{(C5H4NCH2)2NH}]Br,[Re(CO)3{(C5H4NCH2)2NCH2CO2H}]Br,

[Re(CO)3{X(Y)NCH2CO2CH2CH3}]Br (X = Y = 2-pyridylmethyl, X = 2pyridymethyl, Y = 2-

(1-methylimidazolyl)methyl; X = Y = 2-(1-methylimidazolyl)methyl),

[ReBr(CO)3{(C5H4NCH2)NH(CH2C4H3S)}, and

[Re(CO)3{(C5H4NCH2)N(CH2C4H3S)(CH2CO2)}], Inorg. Chem., 41 (24), 6417-6425, 2002.

65. Bayly S.R., Fisher C.L., Storr T., Adam M.J., Orvig C., Carbohydrate Conjugates for

Molecular Imaging and Radiotherapy: 99mTc(I) and 186Re(I) Tricarbonyl Complexes of N-(2 -́

Hydroxybenzyl)-2-amino-2deoxy-D-glucose, Bioconjugate Chem., 15, 923-926, 2004.

66. Benerjee S.R., Maresca K.P., Francesconi L., Valliant J., Babich J.W., New directions in the

coordination chemistry of 99mTc: a reflection on technetium core structures and a strategy for

new chelate design, Nucl. Med. Biol., 32, 1-20, 2005.

Page 9: Referências Bibliográficas - ULisboarepositorio.ul.pt/.../10451/1701/...Bibliograficas.pdf · Referências Bibliográficas 225 retention of astatine-, bismuth-, and lead-radiolabeled

Referências Bibliográficas

229

67. Kramer J. D., Davison A., Davis M. W., Jones A. G., N-(2-Mercaptoethyl)picolylamine as a

Diaminomonothiolate Ligand for the “fac-[Re(CO)3]+” Core, Inorg. Chem., 41 (24), 6181-6183,

2002.

68. Maria L., Paulo A., Santos I.C., Kurz P., Spingler B., Alberto R., Santos I., Very small and

soft scorpionates: water stable technetium tricarbonyl complexes combining a bis-agostic (k3-H,

H, S) binding motif with pendant and integrated bioactive molecules, J. Am. Chem. Soc., 128,

14590-14598, 2006.

69. Mundwiler S., Kündig M., Kirstin O., Alberto R., A new [2 + 1] mixed ligand concept based

on [99(m)Tc(OH2)3(CO)3]+: a basic study, Dalton Trans., 1320-1328, 2004.

70. Petrig J., Schibli R., Dumas C., Alberto R., Schubiger P. A., Derivatization of Glucose and

2-Deoxyglucose for Transition Metal Complexation: Substitution Reactions with

Organometallic 99mTc and Re Precursors and Fundamental NMR Investigations, Chem. Eur. J.,

7 (9), 1868-1873, 2001.

71. Santos I., Paulo A., Correia J.D.G., Rhenium and technetium complexes anchored by

phosphines and scorpionates for radiopharmaceutical applications, Top. Curr. Chem., 252, 45-

84, 2005.

72. Schibli R., Bella R.L., Alberto R., Garcia-Garayoa E., Ortner K., Abram U., Schubiger P.A.,

Influence of the denticity of ligand systems on the in vitro and in vivo behavior of 99mTc(I)-

tricarbonyl complexes: a hint for the future functionalization of biomolecules, Bioconjugate

Chem., 11, 345-351, 2000.

73. Garcia R., Paulo A., Domingos A., Santos I., Rhenium(I) organometallic complexes with

novel bis(mercaptoimidazolyl)borates and with hydrotris(mercaptoimidazolyl)borate: chemical

and structural studies, J. Organometallic Chem., 632, 41-48, 2001.

74. Garcia R., Domingos A., Paulo A., Santos I., Alberto R., Reactivity of [Re{k3-H)B(timMe =

2-Mercapto-1-methylimidazolyl) toward Neutral Substrates, Inorg. Chem., 41, 2422-2428,

2002.

Page 10: Referências Bibliográficas - ULisboarepositorio.ul.pt/.../10451/1701/...Bibliograficas.pdf · Referências Bibliográficas 225 retention of astatine-, bismuth-, and lead-radiolabeled

Referências Bibliográficas

230

75. Alves S., Paulo A., Correia J. D. G., Domingos A., Santos I., Coordination capabilities of

pyrazolyl containing ligands towards the fac-[Re(CO)3]+ moiety; J. Chem. Soc., Dalt. Trans.,

24, 4714-4719, 2002.

76. Alves S., Paulo A., Correia J.D.G., Gano L., Santos I., in Nicolini M., Mazzi U. (Eds.),

Technetium, Rhenium and Other Metals in Chemistry and Nuclear Medicine, vol 6, SGE

Editor-iali, Padova, Italy, 139-141, 2002a.

77. Alves S., Paulo A., Correia J. D. G., Gano L., Smith C. J., Hoffman T. J., Santos I.,

Pyrazolyl derivatives as bifunctional chelators for labelling biomolecules with the fac-

[M(CO)3]+ moiety (M=99mTc, Re): synthesis, characterization and biological behaviour,

Bioconjugate Chem., 16, 438-449, 2005.

78. Bandoli G., Tisato F., Dolmella A., Agostini S., Structural overview of technetium

compounds (200-2004), Coord. Chem. Rev., 250, 561-573, 2006.

79. Oliveira R., Santos D., Ferreira D., Coelho P., Veiga F., Preparações radiofarmacêuticas e

suas aplicações, Rev. Bras. Cienc. Farm.,42 (2), 2006.

80. Silva C.R., Valsa J.O., Canine M.S., Caldeira-de-Araujo A., Bernardo-Filho M., Evaluation

of 99mtechnetium decay on Escherichia coliminactivation: effects of physical or chemical

agents, Yale J. Biol. Med., 71(1), 7-14, 1998.

81. Pedraza-Lopez M, Ferro-Flores G., Mendiola-Cruz T., Morales-Ramirez P., Assessment of

radiation-induced DNA damage caused by the incorporation of 99mTc-radiopharmaceuticals in

murine lymphocytes using single cell gel electrophoresis, Mutat. Res.-Gen. Tox. Env. Mutag.,

465(1-2), 139-144, 2000

82. Griffiths G.L., Govindan S.V., Sgouros G., Ong G.L., Goldenberg D. M., Mattes M.J.,

Cytotoxicity with auger electron-emitting radionuclides delivered by antibodies, Int. J. Cancer,

81, 985-992, 1999.

83. Schipper M.L., Riese C.G.U., Seitz S., Weber A., Béhé M., Schurrat T., Schramm N., Keil

B., Alfke H., Behr T.M., Efficacy of 99mTc pertechnetate and 131I radioisotope therapy in

Page 11: Referências Bibliográficas - ULisboarepositorio.ul.pt/.../10451/1701/...Bibliograficas.pdf · Referências Bibliográficas 225 retention of astatine-, bismuth-, and lead-radiolabeled

Referências Bibliográficas

231

sodium/iodide symporter (NIS)-expressing neuroendocrine tumors in vivo, Eur. J. Nucl. Med.

Mol. Imaging, 34, 638-650, 2007.

84. Agorastos N., Borsig L., Renard A., Antoni P., Viola G., Spingler B., Kurz P., Alberto R.,

Cell-specific and nuclear targeting with [M(CO)3]+ (M=99mTc, Re)-Based Complexes

Conjugated to Acridine Orange and Bombesin, Chem. Eur. J., 13, 3842-3852, 2007.

85. Stephenson K.A., Banerjee S.R., Besanger T., Sogbein O.O., levadala M.K., McFariane N.,

Lemon J.A., Boreham D.R., Maresca K.P., Brennan J.D., Babich J.W., Zubieta J., Valliant J.F.,

Bridging the gap between in vitro and in vivo imaging: isostructural Re and 99mTc complexes for

correlating fluorescence and radioimaging studies, J. Am. Chem. Soc., 126, 8598-8599, 2004.

86. Bullok K.E., Dyszlewski M., Prior J.L., Pica C.M., Sharma V., Piwnica-Worms D.,

Characterization of Novel Histidine-Tagged tat-Peptide Complexes Dual-Labeled with 99mTc-

Tricarbonyl and Fluorescein for Scintigraphy and Fluorescence Microscopy, Bioconjugate

Chem., 13, 1226-1237, 2002.

87. Polyakov V., Sharma V., Dahlheimer J.L., Pica C. M., Luker G. D., Piwnica-Worms D.,

Novel Tat-Peptide Chelates for Direct Transduction of Technetium-99m and Rhenium into

Human Cells for Imaging and Radiotherapy, Bioconjugate Chem., 11, 762-771, 2000.

88. Alves S., Correia J.D.G., Santos I., Veerendra B., Sieckman G.L., Hoffman T.J., Rold T.L.,

Figueroa S.D., Retzloff L., McCrate J., Prasanphanich A., Smith C.J., Pyrazolyl conjugates of

bombesin: a new tridentate ligand framework for the stabilization of fac-[M(CO)3]+ moiety,

Nucl. Med.. Biol., 33 (5), 625-634, 2006

89. Alves S., Correia J.D.G., Gano L., Rold T.L., Prasanphanich A., Haubner R., Rupprich M.,

Alberto R., Decristoforo C., Santos I., Smith C.J., In vitro and in vivo evaluation of a novel 99mTc(CO)3-pyrazolyl conjugate of cyclo-(Arg-Gly-Asp-D-Tyr-Lys), Bioconjugate Chem., 18,

530-537, 2007.

90. Paulo A., Correia J.D.G., Campello M.P.C., Santos I., A short ride on scorpionates: from d-

to f-elements, Polyhedron, 23, 331-360, 2004.

Page 12: Referências Bibliográficas - ULisboarepositorio.ul.pt/.../10451/1701/...Bibliograficas.pdf · Referências Bibliográficas 225 retention of astatine-, bismuth-, and lead-radiolabeled

Referências Bibliográficas

232

91. Seymore S.B., Brown S.N., Charge effects on oxygen atom transfer, Inorg. Chem., 39, 325-

332, 2000.

92. Porchia M., Papini G., Santini C., Lobbia G.G., Pellei M., Tisato F., Bandoli G., Dolmella

A., Novel rhenium(V) oxo complexes containing bis(pyrazol-1-yl)acetate and bis(pyrazol-1-yl)

sulfonate as tripodal N,N,O-heteroscorpionate ligands, Inorg. Chem., 44, 4045-4054, 2005.

93. Alegria E.C.B., Martins L.M.D.R.S., Haukka M., Pombeiro A.J.L., Rhenium complexes of

tris(pyrazolyl)methanes and sulfonate derivative, Dalton Trans., 4954-4961, 2006.

94. Cowley A.R., Dilworth J.R., Salichou M., Syntheses and structures of pyrazolylmethane

complexes of rhenium(III), (IV) and (V), Dalton Trans., 1621-1629, 2007.

95. Gabriel M., Decristofore C., Maina T., Nock B., vonGuggenberg E., Cordopatis P.,

Moncayo R., 99mTc-N4-[Tyr3]octreotate versus 99mTc-EDDA/HYNIC-[Tyr3]octreotide: an

intrapatient comparison of two novel technetium-99m labelled tracers for somatostatin receptor

scintigraphy, Cancer Biotherapy & Radiopharmaceuticals, 19(1), 73-79, 2004.

96. Maina T., Nock B.A., Cordopatis P., Bernard B.F., Breeman W.A.P., Gameren A.V., Berg

R.V.D., Reubi J.C., Krenning E.P., Jong M.D., [99mTc]Demotate 2 in the detection of sst2-

positive tumours: a preclinical comparison with [111In]DOTA-tate, Eur. J. Nucl. Med. Mol.

Imag., 33(7), 831-840, 2006.

97. Nock B.A., Nikolopoulou A., Reubi J.C., Maes V., Conrath P., Tourwé D., Maina T.,

Toward stable N4-modified neurotensins for NTS1-receptor-targeted tumor imaging with 99mTc,

J. Med. Chem., 49, 4767-4776, 2006.

98. Pietzsch H.J., Gupta A., Reisgys M., Drews A., Seifert S., Syhre R., Spies H., Alberto R.,

Abram U., Schubiger P.A., Johannsen B., Chemical and biological characterization of

technetium(I) and rhenium(I) tricarbonyl complexes with dithioether ligands serving as linkers

for coupling the Tc(CO)3 and Re(CO)3 moieties to biologically active molecules, Bioconjugate

Chem., 11, 414-424, 2000.

Page 13: Referências Bibliográficas - ULisboarepositorio.ul.pt/.../10451/1701/...Bibliograficas.pdf · Referências Bibliográficas 225 retention of astatine-, bismuth-, and lead-radiolabeled

Referências Bibliográficas

233

99. Karagiorgou O., Patsis G., Pelecanou M., Raptopoulou C.P., Terzis A., Siatra-Papastaikoudi

T., Alberto R., Pirmettis I., Papadopoulos M., (S)-(2-(2 -́pyridyl)ethyl)cysteamine and (S)-(2-

(2 -́pyridyl)ethyl)-D,L-homocysteine as ligands for the “fac-[M(CO)3]+” (M = Re, 99mTc) core,

Inorg. Chem., 44, 4118-4120, 2005.

100. Staveren D.R.V., Benny P.D., Wailbel R., Kurz P., Pak J.K., Alberto R., S-Functionalized

cysteine: powerful ligands for the labelling of bioactive molecules with

triaquatricarbonyltechnetium-99m(1+)([99mTc(OH2)3(CO)3]+), Helvetica Chim. Acta, 88, 447-

459, 2005.

101. He H., Lipowska M., Xu X., Taylor A.T., Carlone M., Marzilli L.G., Re(CO)3 complexes

synthesized via an improved preparation of aqueous fac-[Re(CO)3(H2O)3]+ as an aid in assessing 99mTc imaging agents. Structural characterization and solution behaviour of complexes with

thioether-bearing amino acids as tridentate ligands, Inorg. Chem., 44, 5437-5446, 2005.

102. He H., Lipowska M., Xu X., Taylor A.T., Marzilli L.G., Rhenium analogues of promising

renal imaging agents with a {99mTc(CO)3}+ core bound to cysteine-derived dipeptides, including

lanthionine, Inorg. Chem., 46, 3385-3394, 2007.

103. He H., Lipowska M., Christoforou A.M., Marzilli L.G., Taylor A.T., Initial evaluation of

new 99mTc(CO)3 renal imaging agents having carboxyl-rich thioether ligands and chemical

characterization of Re(CO)3 analogues, Nucl. Med. Biol., 34, 709-716, 2007.

104. Pietzsch H.J., Spies H., Leibnitz P., Reck G., Technetium and rhenium complexes with

thioether ligands-IV. Synthesis and structural characterization of binuclear oxorhenium(V)

complexes with bidentate thioether coordination, Polyhedrom, 14(13-14), 1849-1853, 1995.

105. Reisgys M., Spies H., Johannsen B., Leibnitz P., Pietzsch H.J., Technetium and rhenium

complexes with thioether ligands. 6. Synthesis and structural characterization of mixed-ligand

oxorhenium(V) complexes containing bidentate dithioethers and monothiolato ligands, Chem.

Berichte-Recueil, 130(9), 1343-1347, 1997.

106. Pietzsch H.J., Reisgys M., Spies H., Leibnitz P., Johannsen B., Technetium and rhenium

complexes with thioether ligands. 5. Synthesis and structural characterization of neutral

Page 14: Referências Bibliográficas - ULisboarepositorio.ul.pt/.../10451/1701/...Bibliograficas.pdf · Referências Bibliográficas 225 retention of astatine-, bismuth-, and lead-radiolabeled

Referências Bibliográficas

234

oxorhenium(V) complexes with tridentate dithioethers, Chem. Berichte-Recueil, 130(3), 357-

364, 1997.

107. Holzer W., Seiringer G., N-1 Substituted ethyl 4-pyrazolecarboxylates: synthesis and

spectroscopic investigations, J. Heterocyclic Chem., 30, 865-872, 1993.

108. Haanstra W.G., Driessen W.L. and Reedijk J., Unusual chelating properties of the ligand

1,8-bis(3,5-dimethyl-1-pyrazolyl)-3,6-dithiaoctane (bddo). Crystal Structures of

Ni(bddo)(NCS)2,Zn(bddo)(NCS)2 and Cd2(bddo)(NCS)4, J. Chem. Soc Dalton Trans., 2309-

2314, 1989.

109. Salvatore R.N., Yoon C.H., Jung K.W., Synthesis of secondary amines, Tetrahedron, 57,

7785-7811, 2001.

110. Rosini M., Bixel M.G., Marucci G., Budriesi R., Krauss M., Bolognesi M.L., Minarini A.,

Tumiatti V., Hucho F., Melchiorre C., Structure-activity relationships of methoctramine-related

polyamines as muscular nicotinic receptor noncompetitive antagonists. 2.1 Role of

polymethylene chain lengths separating amine functions and of substituents on the terminal

nitrogen atoms, J. Med. Chem., 45, 1860-1878, 2002.

111. Holmes R.J., McKeage M.J., Murray V., Denny W. A., McFadyen W.D., cis-

Dichloroplatinum(II) complexes tethered to 9-aminoacridine-4-carboxamides: synthesis and

action in resistant cell lines in vitro, J. Inorg. Bioch., 85, 209-217, 2001.

112. Garcia-Antón J., Pons J., Solans X., Mercè Font-Bardia and Josep Ros, Synthesis,

Characterisation, and X-ray Crystal Structure of New Ni(II), Pd(II), and Pt(II) Complexes of

Tridentate Pyrazole-Based Ligands with an NOS-Donor Set. Eur. J. Inorg. Chem., 2992-3000,

2003.

113. a) Parshall G.W., Shive L.W., Cotton F.A., Phosphine complexes of rhenium, Inorg.

Synth., XVII, 110-111, 1977; b) Ram M.S., Hupp J.T, Generalized synthesis of cis- and trans-

dioxorhenium(V) (bi)pyridyl complexes, Inorg.Chem., 30, 130-133, 1991.

Page 15: Referências Bibliográficas - ULisboarepositorio.ul.pt/.../10451/1701/...Bibliograficas.pdf · Referências Bibliográficas 225 retention of astatine-, bismuth-, and lead-radiolabeled

Referências Bibliográficas

235

114. Francesconi L.C., Graczyk G., Wehrli S., Shaikh S.N., McClinton D., Liu S., Zubieta J.,

Kung H.F., Synthesis and characterization of neutral MVO (M = Tc, Re) amine-thiol complexes

containing a pendant phenylpiperidine group, Inorg. Chem., 32, 3114-3124.

115. Hilger C.S., Noll B., Blume F., Leibnitz P., Johannsen B., Tc(V) and Re(V) Complxes of

N-(MAG1)-Histamine, Technetium, Rhenium and Other Metals in Chemistry and Nuclear

Medicine, 221-224, 1999.

116. Parker D., Roy P.S., Synthesis and characterization of stable rhenium(V) dioxo complexes

with acyclic tetraamine ligands, [LReO2]+, Inorg. Chem., 27, 4127-4130, 1988.

117. Luna S.A., Bolzati C., Duatti A., Zucchni G.L., Bandoli G., Refosco F., Formation of the

trans-[ReO2]+ group from the reactions of ReNCl2(PPh3)2, ReCl4(PPh3)2, and

ReCl3(CH3CN)(PPh3)2 with chelating amines and tetraazamacrocycles. Crystal structure of

trans-[ReO2(cyclam)](PF6) (cyclam = 1,4,8,11-tetraazacyclotetradecane), Inorg. Chem., 31,

2595-2598.

118. Nugent W.A., Mayer J.M., Metal-Ligand Multiple Bonds, J. Wiley & Sons, 1988.

119. Hansen L., Lampeka Y.D., Gavrish S.P., Xu X., Taylor A.T., Marzilli L.G., Re(V)

complexes with an open-chain quadridentate ligand containing two amine and two amido

donors. Synthesis, characterization, and solution equilibria of Re2O3(dioxo-tetH4)2 and

[ReO(H2O)(dioxo-tetH4)]Cl (dioxo-tetH6 = 1,4,8,11-tetraazaundecane-5,7-dione), Inorg. Chem.,

39, 5859-5866, 2000.

120. Bélanger S., Beauchamp A., Preparation and protonation studies of trans-dioxorhenium(V)

complexes with imidazoles, Inorg. Chem., 35, 7836-7844, 1996.

121. Xu L., Pierreroy J., Patrick B.O., Orvig C., Chemistry of Re with N,N’-bis(2-

pyridylmethyl)ethylenediamine (H2pmen): hydrolysis, dehydrogenation, and ternary complexes,

Inorg. Chem., 40, 2005-2010, 2001.

122. Paulo A., Domingos A, Santos I, Coordination of Tetrakis(pyrazolyl)borate in Rhenium

Complexes Containing the [ReV=O]3+ Core, Inorg. Chem., 1996, 35, 1798-1807.

Page 16: Referências Bibliográficas - ULisboarepositorio.ul.pt/.../10451/1701/...Bibliograficas.pdf · Referências Bibliográficas 225 retention of astatine-, bismuth-, and lead-radiolabeled

Referências Bibliográficas

236

123. Paulo A., Correia J. D. G., Santos I., Rhenium complexes with poly(pyrazolyl)borates,

Trends in Inorg. Chem., 5, 57-86, 1998.

124. Xavier C., Paulo A., Domingos A., Santos I., Synthesis and structural studies of

rhenium(V) complexes stabilized by a monoanionic cyclen ligand, Eur. J. Inorg. Chem., 243-

249, 2004.

125. Lock C.J.L. and Turner G.; Studies of rhenium-oxigen bond. II. The crystal and molecular

structure of µ-oxobis(cis-dihloro-cis-di(pyridine)-trans-oxorhenium(V)),

ORe(C5H5N)2Cl2ORe(C5H5N)2Cl2O, Can. J. Chem. 56, 179-188, 1978.

126. Alberto R., Egli A., Abram U., Hegetschweiler K., Gramlich V., Schubiger P.A., Synthesis

and reactivity of [Net4]2[ReBr3(CO)3]. Formation and structural characterization of the clusters

[Net4][Re(�3-OH)(�-OH)3(CO)9] and [Net4][Re2(�-OH)3(CO)6] by alkaline titration, J. Chem.

Soc. Dalton Trans., 2815-2820, 1994.

127. Garcia R., Complexos Tricarboonilo de Re(I) e 99mTc com Escorpionatos Doadores de

Enxofre, Aplicações no Desenvolvimento de Radiofármacos para Imagiologia Molecular de

Receptores do Sistema Nervoso Central, Tese de Doutoramento em Química (especialidade

Química Inorgânica) apresentada à Faculdade de Ciências – Universidade de Lisboa, 2005

128. Tan W.B., Bhambhani A., Duff M.R., Rodger A., Kumar C.V., Spectroscopic

Identification of Binding Modes of Anthracene Probes and DNA Sequence Recognition,

Photochemistry and Photobiology, 82, 20-30, 2006.

129. Kumar C.V., Asuncion E.H., DNA binding studies and site selective fluorescence

sensitization of an anthryl probe, J. Am. Chem. Soc., 115, 8547-8553, 1993.

130. Duff M.R., Tan W.B., Bhambhani A., Perrin Jr B.S., Thota J., Rodger A., Kumar C.V.,

Contributions of hidroxyethyl group to the DNA binding affinities of anthracene probes, J.

Phys. Chem. B, 110, 20693-20701, 2006.

Page 17: Referências Bibliográficas - ULisboarepositorio.ul.pt/.../10451/1701/...Bibliograficas.pdf · Referências Bibliográficas 225 retention of astatine-, bismuth-, and lead-radiolabeled

Referências Bibliográficas

237

131. Sissi C., Leo E., Moro S., Capranico G., Mancia A., Menta E., Krapcho A.P., Palumbo M.,

Antitumor aza-antrapyrazoles: biophysical and biochemical studies on 8- and 9-aza

regioisomers, Biochemical Pharmacology 67, 631-642, 2004.

132. Wang C., Delcros J-G., Biggerstaff J., Phanstiel IV O., Synthesis and Biological

Evaluation of N1-(anthracen-9-ylmethyl)triamines as Molecular Recognition Elements for the

Polyamine Transporter, J. Med. Chem., 46, 2663-2671, 2003.

133. Breitbeil III F., Kaur N., Delcros J.G., Martin B., Abboud K.A., Phanstiel IV O., Modeling

the Preferred Shapes of Polyamine Transporter Ligands and Dihydromotuporamine-C Mimics:

Shovel versus Hoe, J. Med. Chem., 49, 2407-2416, 2006.

134. Bullpitt M., Kitching W., Doddrell D., Adcock W., The substituent effect of the

bromomethyl group. A carbon-13 magnetic resonance study, J. Org. Chem., 5(41), 760-766,

1976.

135. Nicolaou K.C., Rutjes F.P.J.T., Theodorakis E.A., Tiebes J., Sato M., Untersteller E., Total

Synthesis of Brevetoxin B. 3. Final Strategy and Completion, J. Amer. Chem. Soc., 117 (41),

10252-10263, 1995.

136. Mason T.J., The oxidation of secondary alcohols with Cr (VI), J. Chem. Educ., 59, 11,

980-981, 1982.

137. Nagawa Y., Suga J., Hiratani K., Koyama E., Kanesato M., [3]Rotaxane synthesized via

covalent bond formation can recognize cations forming a sandwich structure, Chem. Commun.,

749-751, 2005.

138. Zhang L., Meler W.E., Watson E.J., Gibson E.P., Reversal of the regioselectivity of

antrapyrazole formation. A new synthesis of Losoxantrone (DUP941), Tetrahedron L., 35(22),

3675-3678, 1994.

Page 18: Referências Bibliográficas - ULisboarepositorio.ul.pt/.../10451/1701/...Bibliograficas.pdf · Referências Bibliográficas 225 retention of astatine-, bismuth-, and lead-radiolabeled

Referências Bibliográficas

238

139. Hasinoff B.B., Tan K.T., The displacement of iron(III) from its complexes with the

anticancer drugs piroxantrone and losoxantrone by the hydrolyzed form of the cardioprotective

agent dexrazoxane, J. Inorg. Biochem., 77, 257-259, 1999.

140. Joachim J.E., Apostolidis C., Kanellakopulos B., Maier R., Marques N., Meyer D., Muller

J., Matos A.P., Nuber B., Rebizant J., Ziegler M.L., Metallorganische chemie des technetiums

VIII*. Technetium(I)-carbonyl-komplexe mit polypyrazol-1-yl-borato-liganden im vergleich

mit seinen Mn- und Re-homologen, J. Organom. Chem., 448, 119-129, 1993.

141. Schibli R., Katti K.V., Volkert W.A., Barnes C.L., Novel coordination behavior of fac-

[ReBr3(CO)3]2- with 1,3,5-triaza-7-phosphaadamentane (PTA). Systematic investigation on

stepwise replacement of the halides by PTA ligand. Phase transfer studies and x-ray crystal

structure of [Net4]ReBr2(PTA)(CO)3], [ReBr(PTA)2(CO)3], and [Re(PTA)3(CO)3]PF6, Inorg.

Chem., 37, 5306-5312, 1998.

142. Silverstein R.M., Bassler G.C., Morrill T.C., Spectrometric identification of organic

compounds, John Wiley & Sons, 5th ed., 1991.

143. Becker H.C., Nordén B., DNA binding mode and sequence specificity of

piperazinylcarbonyloxyethyl derivatives of anthracene and pyrene, J. Am. Soc., 121, 11947-

11952, 1999.

144. McGhee J.D., Hippel P.H., Theoretical Aspects of DNA-Protein Interactions: Co-operative

and Non-co-operative binding of large ligands to a one-dimensional homogeneous lattice, J.

Mol. Biol., 86, 469-489, 1974.

145. Lo K.K., Tsang K.H., Bifunctional Luminescent Rhenium(I) Complexes Containing an

Extended Planar Diiminne Ligand and a Biotin Moiety, Organometallics, 2004.

146. Ellis L.T., Perkins D.F., Turner P., Hambley T.W., The preparation and characterisation of

cyclam/anthraquinone macrocyle/intercalator complexes and their interations with DNA, Dalton

Trans., 2728-2736, 2003.

Page 19: Referências Bibliográficas - ULisboarepositorio.ul.pt/.../10451/1701/...Bibliograficas.pdf · Referências Bibliográficas 225 retention of astatine-, bismuth-, and lead-radiolabeled

Referências Bibliográficas

239

147. Kumar C.V., Punzalan E.H.A., Tan W.B., Adenine-thymine base pair recognition by an

antryl probe from the DNA minor grove, Tetrahedron, 56, 7027-7040, 2000.

148. Madureira J.P.L., Complexos de ruténio com ligandos politioéteres e/ou polipiridílicos:

síntese, caracterização estrutural e interacção com o DNA, Tese de Doutoramento, Aveiro,

Portugal, 2005.

149. Rodger A., Taylor S., Adlam G., Blagbrough I.S., Haworth I.S., Multiple DNA binding

modes of anthracene-9-carbonyl-N1-spermine, Bioorg. Med. Chem., 3(6), 861-872, 1995.

150. Balasundaram G., Takahashi T., Ueno A., Mihara H., Construction of peptide conjugates

with peptide nucleic acids containing an anthracene probe and their interactions with DNA,

Bioorg. Med. Chem., 9, 1115-1121, 2001

151. Mosmann T., Rapid Colorimetric Assay for Cellular Growth and Survival: Application to

Proliferation and Cytotoxicity Assays, J. Immunol. Methods, 65, 55-63, 1983.

152. Wang W., Yan Y.K., Hor T.S.A., Vittal J.J., Wheaton J.R., Hall I.H., Synthesis, X-ray

structures, and cytotoxicity of rhenium(I) carbonyl 2-(dimethylamino)ethoxide complexes,

Polyhedron 21, 1991-1999, 2002.

153. Zobi F., Spingler B., Alberto R., Guanine and plasmid DNA binding of mono- and

trinuclear fac-[Re(CO)3]+ complexes with amino acids ligands, ChemBioChem, 6, 1397-1405,

6, 2005.

154. Zobi F., Blacque O., Schmalle H., Alberto R., Head-to-Head (HH) and Head-to-Tail (HT)

Conformers of cis-bis Purine Ligands Bound to the [Re(CO)3]+ Core, Inorg. Chem.,

43(6), 2087-2096, 2004.

155. Zobi F., Spingler B., Fox Th., Alberto R., Towards Novel DNA Binding Metal Complexes:

Structure and Basic Kinetic Data of [M(9MeG)2(CH3OH)(CO)3]+ (M = 99Tc, Re),

Inorg. Chem., 42(9), 2818-2820, 2003.

Page 20: Referências Bibliográficas - ULisboarepositorio.ul.pt/.../10451/1701/...Bibliograficas.pdf · Referências Bibliográficas 225 retention of astatine-, bismuth-, and lead-radiolabeled

Referências Bibliográficas

240

156. Smith, P. J., Blunt, N., Wiltshire, M., Hoy, T., Teesdale-Spittle, P., Craven, M. R., Watson,

J. V., Amos, B. A., Errington, R. J., and Patterson, L. H., Characteristics of a novel deep

red/infrared fluorescent cell-permeant DNA probe, DRAQ5, in intact human cells analyzed by

flow cytometry, confocal and multiphoton microscopy, Cytometry, 40, 280-291, 2000.

157. Lansiaux A., Tanious F., Mishal Z., Dassonneville L., Kumar A., Stephens C.E., Hu Q.,

Wilson W.D., Boykin D.W., Bailly C., Distribution of furamide analogues in tumor cells:

targeting of the nucleus or mitochondria depending on the amide substitution, Cancer Research,

62, 7219-7229, 2002.

158. James S., Maresca K.P., Babich J.W., Valliant J. F., Doering L., Zubieta J., Isostructural

Re and 99mTc Complexes of Biotin Derivatives for Fluorescence and Radioimaging Studies,

Bioconjugate Chem., 17, 590-596, 2006

159. Maublant J.C., Zhang Z., Rapp M., Ollier M., Michelot J., Veyre A., In vitro uptake of

Technetium-99m-Teboroxime in Carcinoma Cell Lines and Normal Cells: Comparison with

Technetium-99m-Sestamibi and Thallium-201, J. Nucl. Med., 34(11), 1949-1952, 1993.

160. Barbarics E., Kronauge J.F., Davison A., Jones A.G., Uptake of Cationic Technetium

Complexes in Cultured Human Carcinoma Cells and Human Xenografts, Nucl. Med. Biol., 25,

667-673, 1998.

161. Madar I., Weiss L., Izbicki G., Preferential Accumulation of 3H-Tetraphenyphosphonium

in Non-Small Cell Lung Carcinoma in Mice: Comparison with 99mTc-MIBI, J. Nucl. Med.,

43(2), 234-238, 2002

162. Chiu M. L., Kronauge J. F., Piwnica-Worms D., Effect of Mitochondrial and Plasma

Membrane Potentials on Accumulation of Hexakis (2-Methoxyisobutylisonitrile) Technetium(I)

in Cultured Mouse Fibroblasts, J. Nucl. Med., 31(10), 1646-1653, 1990.

163. Perrin D.D., Armarego W.L.F., Purification of laboratory chemicals; 3ª Ed. Pergamon

Press, Oxford, 1988.

Page 21: Referências Bibliográficas - ULisboarepositorio.ul.pt/.../10451/1701/...Bibliograficas.pdf · Referências Bibliográficas 225 retention of astatine-, bismuth-, and lead-radiolabeled

Referências Bibliográficas

241

164. Ishikawa J., Sakamoto H., Nakao S, Wada H., Silver ion selective fluoroionophores based

on anthracene-linked polythiazaalkane or polythiaalkane derivatives, J. Org. Chem., 64(6),

1913-1921, 1999.

165. Schmidt S.P., Trogler W.C., Basolo F., Reagents for transution metal complex and

organometallic syntheses; Inorg. Synth., Ed R. J. Angelici, Wiley, 28, 162, 1990.

166. Ihmels H., Faulhaber K., Sturm C., Bringmann G., Messer K., Gabellini N., Vedaldi D.,

Viola G., Acridizinium Salts as a Novel Class of DNA-Binding and Site-Selective DNA-

Photodamaging Chromophores, Photochem. Photobiol., 74, 505-511, 2001.

167. Viola G., Dall’Acqua F., Gabellini N., Moro S., Vedaldi D., Ihmels H., Indolo[2,3-b]-

Quinolizinium Bromide: An Efficient Intercalator with DNA-Photodamaging Properties, Chem-

BioChem., 3, 550-558, 2002.

168. Wada A., Kozawa S., Instrument for the studies of differential flow dichroism of polymer

solutions, J. Polym. Sci. Part A, 2, 853-864, 1964

169. Sambrook J., Russell D.W., Molecular Cloning, Chapter 17.26, Cold spring Harbor

Laboratory Press, Cold Spring Harbor, NY, 2001.

170. Fair C.K., Molen, Enraf-Nonius, Delft, The Netherlands, 1990.

171. Sheldrick G.M., SHELXS-97, University of Göttingen, Germany, 1997.

172. Farrugia L.J., ORTEP-3 for Windows - a version of ORTEP-III with a Graphical User

Interface (GUI), J. Appl. Cryst. 30, 565, 1997.

Page 22: Referências Bibliográficas - ULisboarepositorio.ul.pt/.../10451/1701/...Bibliograficas.pdf · Referências Bibliográficas 225 retention of astatine-, bismuth-, and lead-radiolabeled

Referências Bibliográficas

242

Publicações Resultantes do Trabalho Descrito

Artigos em Revistas de Circulação Internacional

• 2004 - Vitor R. F., Alves S., Correia J. D. G., Paulo A., Santos I. Rhenium(I)- and

technetium(I) tricarbonyl complexes anchored by bifunctional pyrazole-diamine and

pyrazole-dithioether chelators. Journal of Organometallic Chemistry 689: 4764-4774.

• 2005 - Marques F., Paulo A., Campello M. P., Lacerda S., Vítor R., Gano L., Delgado

R., Santos I., Radiopharmaceuticals for targeted radiotherapy. Radiation Protection

Dosimetry 116: 601-604.

• 2006 - Moura C., Vítor R. F., Maria L., Paulo A., Santos I. C., Santos I., Rhenium (V)

oxocomplexes with novel pyrazolyl-based N4- and N3S- donor chelators. Dalton

Transactions, 5630-5640.

• 2007 – Vitor R. F., Correia I., Videira M., Marques F., Paulo A., Pessoa J. C., Viola

G., Martins G. G., Santos I., Pyrazolyl-diamine ligands that bear anthracenyl moieties

and their rhenium(I) tricarbonyl complexes: synthesis, characterization and DNA-

binding properties, ChemBioChem (in press).

• 2007 – Technetium-99m organometallics complexes containing DNA binding groups

for nuclear targeting: synthesis, characterisation and biological evaluation (manuscrito

em preparação)

Patentes

• 2004 - Bifunctional Tridentate Pyrazolyl Containing Ligands for Re and Tc

Tricarbonyl Complexes (WO2004091669) Inventor: Santos, Isabel; Galamba, João

D.C.; Paulo, António; Alves, Susana; Vítor, Rute. Applicant: Mallinckrodt Inc.

Page 23: Referências Bibliográficas - ULisboarepositorio.ul.pt/.../10451/1701/...Bibliograficas.pdf · Referências Bibliográficas 225 retention of astatine-, bismuth-, and lead-radiolabeled

Referências Bibliográficas

243

Publicações em Proceedings

• 2006 - Alves S., Vitor R., Raposinho P.D., Marques F., Correia J.D.G., Paulo A.,

Santos I., Metal-based drugs for diagnosis and therapy. Metal Ions in Biology and

Medicine (9) Lisboa. Portugal.