Research & Resources

The following compilation of resources and disease/condition specific research is by no

means comprehensive, but we hope it provides some insight into the broad application of

hyperbaric oxygen therapy and its possible benefits.

General Resources • Hyperbaric Medicine: A Brief History

• Hyperbaric Medicine (Wikipedia)

• Application of medical gases in the field of neurobiology

• FDA Issues Deceptive Statement about HBOT (Hyperbaric Oxygen Therapy) (Press Release–September 10, 2013)

• Hyperbaric Oxygen Therapy – Why the Controversy? Pt 1/3(video)

• Hyperbaric Oxygen Therapy – Why the Controversy? Pt 2/3(video)

• Hyperbaric Oxygen Therapy – Why the Controversy? Pt 3/3(video)

• Hyperbaric oxygen and wound healing (An article summarizing mechanisms of action and general

application of HBOT)

• Hyperbaric oxygen therapy promotes neurogenesis: where do we stand? (An article addressing

autologous neurogenesis and cellular transcription)

• Hyperbaric Medical Solutions News 12 Segment (video)

• Hyperbaric Oxygen Therapy for Wounds

• All the right moves: the need for the timely use of hyperbaric oxygen therapy for treating

TBI/CTE/PTSD • SEVEN DAYS ARTICLE MAY 31 2017

Acute Severe Problems From Accidents (i.e. Crushed Leg, Arm, Fingers)

• Successful Treatment of Lower Limb Complex Regional Pain Syndrome following Three Weeks of

Hyperbaric Oxygen Therapy.

• Case Report: Successful Treatment Of Acute Exertional Paraspinal Compartment Syndrome With

Hyperbaric Oxygen Therapy

• The effect of hyperbaric oxygen in crush injuries and skeletal muscle-compartment

syndromes (abstract)

• Effects of hyperbaric oxygen therapy on facial nerve regeneration (abstract)

• Fasciotomy closure using simultaneous vacuum-assisted closure and hyperbaric oxygen (abstract)

• Treatment of open fractures and crush injuries (abstract) • Severe lower limb crush injury and the role of hyperbaric oxygen treatment: a case report. (abstract)

• Hyperbaric Oxygen Treatment for Reflex Sympathetic Dystrophy Syndrome RSD (video)

Anemia

• The effect of hyperbaric oxygen on severe anemia (abstract)

• A systematic review of the application of hyperbaric oxygen in the treatment of severe anemia: an

evidence-based approach (abstract)

Arthritis–Rheumatoid, Osteoarthritis & Osteoarthrosis

• Hyperbaric Oxygen Treatments for Rheumatoid Arthritis (pdf)

• Effects of exposure to hyperbaric oxygen on oxidative stress in rats with type II collagen-induced

arthritis (abstract)

• Hyperbaric oxygenation in the comprehensive therapy of patients with rheumatoid arthritis (clinico-immunologic study)(abstract)

• Radiation-modifying effect of oxygen barotherapy in complex treatment of patients with rheumatoid

arthritis and osteoarthrosis (abstract)

• Therapeutic effect of hyperbaric oxygen in psoriasis vulgaris

• Pain improvement in rheumatoid arthritis with hyperbaric oxygen: report of three cases

• Oxygen Oasis Center for Healing: Rheumatoid Arthritis

• Hyperbaric Oxygen therapy helps Osteoarthritis and degenerative joint/cartilage disease (article)

Athletic Injuries & Performance

• Hyperbaric Oxygen Effects on Sports Injuries

• Hyperbaric oxygen therapy (1.5 ATA) in treating sports related TBI/CTE: two case reports

• Hyperbaric oxygen as an adjuvant for athletes (abstract) • Hyperbaric Therapy for Sports Recovery (abstract)

• Darren Sharper’s Hyperbaric Chamber (video)

Autism, Down Syndrome

• Hyperbaric Oxygen for Bacteria, Viruses, & Yeast

• Hyperbaric oxygen treatment in autism spectrum disorders

• How hyperbaric oxygen therapy helped my daughter with down syndrome

• Children With Autism and Hyperbaric Oxygen Chamber Studies Part 1 (video)

• HBOT for Autism (video)

• CTV News clip – Hyperbaric Oxygen Therapy (HBOT) and Autism at Under Pressure Inc. (video)

• Hyperbaric Oxygen Therapy Works (Autism) (video) • Autism Therapy Success Stories in Minnesota using Hyperbaric Oxygen Therapy HBOT (video)

• Hyperbaric oxygen therapy in Thai autistic children

• The effects of hyperbaric oxygen therapy on oxidative stress, inflammation, and symptoms in children

with autism: an open-label pilot study

• Hyperbaric treatment for children with autism: a multicenter, randomized, double-blind, controlled

trial

• Care: The Center for Autism and Education

• TAKA Talk About Curing Autism and A Primer of Hyperbaric Therapy for Parents

• Hyperbaric oxygen therapy might improve certain pathophysiological findings in autism (abstract)

• How mild hyperbaric oxygen therapy works and why it is good for our children (pdf) • Hyperbaric oxygen therapy promotes neurogenesis: where do we stand?

• Brief report: Hyperbaric oxygen therapy (HBOT) in children with autism spectrum disorder: a

clinical trial (abstract)

• Hyperbaric Oxygen Treatments for Autistic Children (video)

• Therapeutic use of hyperbaric oxygen therapy for children with autism spectrum disorder.

Autoimmune Disorders/ Graft vs. Host Disease

• Suppressive effect of hyperbaric oxygenation on immune responses of normal and autoimmune mice

• Ischemic scleroderma wounds successfully treated with hyperbaric oxygen therapy (abstract)

• Improvement of attention span and reaction time with hyperbaric oxygen treatment in patients with

toxic injury due to mold exposure

• Hyperbaric oxygen and lymphoid system function: A review supporting possible intervention in

tissue transplantation(abstract)

• Refractory vasculitic ulcer of the toe in adolescent suffering from Systemic Lupus Erythematosus

treated successfully with hyperbaric oxygen therapy • Allergy & Immunity – Wisconsin Hyperbarics – Myasthenia Gravis

• Therapeutic effect of hyperbaric oxygen in psoriasis vulgaris

• Use of Hyperbaric Oxygen Therapy in the Treatment of Non-healing Ulcers

• Hyperbaric oxygenation enhances transplanted cell graft and functional recovery in the infarct heart

Bone Disorders/Conditions/Pain

• Effect of hyperbaric oxygen on bone healing after enucleation of mandibular cysts: a modified case

control study(abstract)

• There may be a role for hyperbaric oxygen therapy in transient osteoporosis of the hip (abstract)

• The influence of hyperbaric oxygen treatment on the healing of experimental defects filled with

different bone graft substitutes

• Bone disease with pain. Osteomyelitis in the long bone (abstract)

Cancer & Cancer Treatment and Radiation Damage/Burns

• Efficacy of hyperbaric oxygen therapy combined with mild hyperthermia for improving the anti-

tumour effects of carboplatin.

• Hyperbaric oxygen as an adjunctive therapy in treatment of malignancies, including brain tumours.

• Non-Toxic Metabolic Management of Metastatic Cancer in VM Mice: Novel Combination of

Ketogenic Diet, Ketone Supplementation, and Hyperbaric Oxygen Therapy.

• Synergistic Inhibitory Effect of Hyperbaric Oxygen Combined with Sorafenib on Hepatoma

Cells

• Effects of different doses of hyperbaric oxygen on cisplatin-induced nephrotoxicity. • Hyperoxic treatment induces mesenchymal-to-epithelial transition in a rat adenocarcinoma model.

• The Ketogenic Diet and Hyperbaric Oxygen Therapy Prolong Survival in Mice with Systemic

Metastatic Cancer • Long-term experience of hyperbaric oxygen therapy for refractory radio- or chemotherapy-induced

haemorrhagic cystitis

• Hyperbaric oxygen therapy for late radiation-induced tissue toxicity:outcome measures in breast cancer patients

• American Cancer Society

• Hyperbaric oxygen therapy and cancer—a review

• Effect of hyperbaric oxygen treatment on oxygen tension and vascular capacity in irradiated skin and

mucosa(abstract)

• Dr. Paul Harch HBOT in Cancer Lecture (video)

• The efficacy of hyperbaric oxygen therapy in the treatment of radiation-induced late side effects

• Hyperbaric oxygen therapy for late radiation tissue injury (abstract)

• Hyperbaric oxygen therapy for radiation-induced cystitis and proctitis (abstract)

• Hyperbaric oxygen treatment in radiation-induced cystitis and proctitis: a prospective cohort study on patient-perceived quality of recovery (abstract)

• Issels Integrative Oncology

• The use of hyperbaric oxygen for treating delayed radiation injuries in gynecologic malignancies: a

review of literature and report of radiation injury incidence (abstract)

• Hyperbaric oxygenation therapy alleviates chronic constrictive injury-induced neuropathic pain and

reduces tumor necrosis factor-alpha production. (abstract)

• Hyperbaric oxygen treatment improved neurophysiologic performance in brain tumor patients after

neurosurgery and radiotherapy: a preliminary report (abstract) • Hyperbaric oxygenation for tumour sensitisation to radiotherapy (abstract)

• Hyperbaric oxygen therapy effectively treats long-term damage from radiation therapy (from UCLA

Health)

• Early hyperbaric oxygen therapy for reducing radiotherapy side effects: early results of a

randomized trial in oropharyngeal and nasopharyngeal cancer (abstract)

• Improved quality of life with hyperbaric oxygen therapy in patients with persistent pelvic radiation-

induced toxicity(abstract)

• Does hyperbaric oxygen administration decrease side effect and improve quality of life after pelvic

radiation?(abstract)

• The effect of hyperbaric oxygen therapy on quality of life in oral and oropharyngeal cancer patients treated with radiotherapy (abstract)

• Treatment of refractory radiation-induced hemorrhagic proctitis with hyperbaric oxygen

therapy (abstract)

• Treatment of radiation proctitis with hyperbaric oxygen (abstract)

• Hyperbaric oxygen therapy for delayed radiation injuries in gynecological cancers (abstract)

• Hyperbaric oxygen: does it promote growth or recurrence of malignancy? (abstract)

• Does hyperbaric oxygen treatment have the potential to increase salivary flow rate and reduce

xerostomia in previously irradiated head and neck cancer patients? A pilot study (abstract)

• The effect of hyperbaric oxygenation on postradiation xerostomia and saliva in patients with head and neck tumours(abstract)

• Hyperbaric oxygen therapy for late radiation tissue injury in gynecologic malignancies

• Hyperbaric oxygen therapy for treatment of adverse radiation effects after stereotactic radiosurgery

of arteriovenous malformations: case report and review of literature (abstract)

• Hyperbaric oxygen in the treatment of a radiosurgical complication: technical case report (abstract)

• Usefulness of hyperbaric oxygen in the treatment of radionecrosis and symptomatic brain edema

after LINAC radiosurgery (abstract)

• Treatment of a radiation-induced rectal ulcer with hyperbaric oxygen therapy in a man with prostate

cancer (abstract)

• Lung metastatic load limitation with hyperbaric oxygen (abstract) • Hyperbaric oxygen and malignancies: a potential role in radiotherapy, chemotherapy, tumor surgery

and phototherapy(abstract)

• The utility of hyperbaric oxygen therapy to treat recurrent acute bowel obstruction after previous

pelvic radiotherapy: a case series (abstract)

• Potential roles of hyperbaric oxygenation in the treatments of brain tumors. (abstract)

• Effects of radiotherapy after hyperbaric oxygenation on malignant gliomas. (abstract)

• Can hyperbaric oxygenation decrease doxorubicin hepatotoxicity and improve regeneration in the

injured liver?

• Stem Cell Collection And Hyperbaric Oxygen Treatment

• Hyberbaric Oxygen’s affect on Tumour Growth • Trial of HBOT in patients with chronic Arm Lymphoedema

• Efficacy of Metabolically Supported Chemotherapy Combined with Ketogenic Diet, Hyperthermia,

and Hyperbaric Oxygen Therapy for Stage IV Triple-Negative Breast Cancer

• Oxygen-dependent regulation of tumor growth and metastasis in human breast cancer xenographs

Cardiac Disorders/Heart Disease/MI/Acute Coronary Syndrome

• Hyperbaric oxygenation enhances transplanted cell graft and functional recovery in the infarct heart

• Oxygen and oxygenation in stem-cell therapy for myocardial infarction

• Hyperbaric oxygenation enhances transplanted cell graft and functional recovery in the infarct heart

• Hyperbaric oxygen therapy for acute coronary syndrome • Stem cell mobilization by hyperbaric oxygen (pdf)

• Hyperbaric oxygen therapy for treatment of neurologic sequela after atrioesophageal fistula. (pdf)

• Hyperbaric, Cardiovascular Effects

• Hyperbaric oxygenation enhances transplanted cell graft and functional recovery in the infarct heart

Cerebral Ischemia/Edema

• Hyperbaric Oxygen Reduces Blood–Brain Barrier Damage and Edema After Transient Focal

Cerebral Ischemia

• Hyperbaric oxygen therapy and cerebral ischemia: neuroprotective mechanisms (abstract)

• Hyperbaric oxygen in the treatment of a radiosurgical complication: technical case report (abstract)

• Hyperbaric oxygen preconditioning reduces postoperative brain edema and improves neurological

outcomes after surgical brain injury (abstract) • Usefulness of hyperbaric oxygen in the treatment of radionecrosis and symptomatic brain edema

after LINAC radiosurgery (abstract)

• Effects of early hyperbaric oxygen therapy on clinical outcome in postoperative patients with

intracranial aneurysm(abstract)

• Hyperbaric oxygenation enhances transplanted cell graft and functional recovery in the infarct heart

Cerebral Palsy

• Hyperbaric Oxygen Therapy in the Management of Cerebral Palsy • Cerebral Palsy Study Dispels Inflated Costs and Biases

• Hyperbaric Oxygenation Therapy in the Treatment of Cerebral Palsy-A Review and Comparison to

Currently Accepted Therapies

• Hyperbaric Oxygen Therapy (hbot) and Cerebral Palsy (cp) (video) • Grace, a Cerebral Palsy Patient treated with Hyperbaric Oxygen Therapy at the Sahara Clinic (video)

• Cerebral Palsy Testimonial – How Stem Cells & Hyperbaric Oxygen Helped Cerebral Palsy (video)

• Causes of Cerebral Palsy Oxygen Therapy in the Neonatal Period Treatment of Cerebral Palsy with

HBOT

Conclusions

Colitis/Crohn’s Disease/Irritable Bowel Syndrome/Other GI Disorders

• Hyperbaric oxygen therapy stimulates colonic stem cells and induces mucosal healing in patients

with refractory ulcerative colitis: a prospective case series

• Effect of hyperbaric oxygenation on normalization of intestinal function after surgical treatment of

Hirschsprung disease and anorectal developmental defects in children

• Hyperbaric oxygen treatment for inflammatory bowel disease • Effect of growth hormone, hyperbaric oxygen and combined therapy on the gastric serosa

• Hyperbaric oxygen: a novel modality to ameliorate experimental colitis

• Hyperbaric oxygen therapy for severe ulcerative colitis (abstract)

• Hyperbaric oxygen therapy is as effective as dexamethasone in the treatment of TNBS-E-induced

experimental colitis(abstract)

• Efficacy of hyperbaric oxygen in patients with Crohn’s disease: two case reports (abstract)

• Crohn’s disease and hyperbaric oxygen therapy (abstract)

• A favourable response to surgical intervention and hyperbaric oxygen therapy in pyoderma

gangrenosum (abstract)

• Computed tomography colonography imaging of pneumatosis intestinalis after hyperbaric oxygen

therapy: a case report

• The utility of hyperbaric oxygen therapy to treat recurrent acute bowel obstruction after previous

pelvic radiotherapy: a case series (abstract) • Systematic review: The safety and efficacy of hyperbaric oxygen therapy for inflammatory bowel

disease. (abstract)

• Hyperbaric oxygen therapy for chronic antibiotic-refractory ischemic pouchitis.

• Hyperbaric oxygen treatment for inflammatory bowel disease: a systematic review and

analysis

Cystitis/Other GU Disorders

• Long-term experience of hyperbaric oxygen therapy for refractory radio- or chemotherapy-induced

haemorrhagic cystitis

• A cost-analysis case study of radiation cystitis treatment including hyperbaric oxygen

therapy (abstract)

• Hyperbaric oxygen-A new horizon in treating cyclophosphamide-induced hemorrhagic cystitis

• Hyperbaric oxygen therapy for painful bladder syndrome/interstitial cystitis resistant to conventional

treatments: long-term results of a case series in Japan • Hyperbaric oxygen treatment in radiation-induced cystitis and proctitis: a prospective cohort study

on patient-perceived quality of recovery (abstract)

• Hyperbaric Oxygen for the Treatment of Interstitial Cystitis-Long-Term Results of a Prospective

Pilot Study

• Safety and efficacy of hyperbaric oxygen therapy for the treatment of interstitial cystitis: a

randomized, sham controlled, double-blind trial. (abstract)

• Severe cyclophosphamide-induced haemorrhagic cystitis treated with hyperbaric oxygen (abstract)

• Treatment of a radiation-induced rectal ulcer with hyperbaric oxygen therapy in a man with prostate

cancer (abstract) • Possible application of hyperbaric oxygen technology in the management of urogenital and renal

diseases (abstract)

• Hyperbaric Oxygen in the Treatment of Calciphylaxis: A case series and literature review. (abstract)

• Emphysematous cystitis: Report of 2 cases with different outcomes.

• Late rectal and bladder toxicity following radiation therapy for prostate cancer: Predictive factors

and treatment results.

• Healing of spongiosus-cutaneous fistula with hyperbaric oxygen therapy (HBOT): a case report.

• Clinical utility of hyperbaric oxygen therapy in genitourinary medicine

Dementia/Alzeimer’s Disease

• Treatment of post-anesthesia dementia with perispinal etanercept injection and hyperbaric oxygen

therapy: a case report. • Reflections on the neurotherapeutic effects of hyperbaric oxygen, Expert Review of

Neurotherapeutics, Informa Healthcare

• Oxygen, a Key Factor Regulating Cell Behavior during Neurogenesis and Cerebral Diseases

• Hyperbaric oxygen therapy for vascular dementia (abstract)

• Hyperbaric oxygen therapy improves neurogenesis and brain blood supply in piriform cortex in rats

with vascular dementia (abstract)

• The protective effect of hyperbaric oxygen and Ginkgo biloba extract on Aβ25-35-induced oxidative

stress and neuronal apoptosis in rats (abstract)

• Hyperbaric oxygen therapy ameliorates pathophysiology of 3xTg-AD mouse model by attenuating

neuroinflammation(abstract)

• Hyperbaric Oxygen Therapy and Alzheimer’s Disease (article)

• Hyperbaric oxygen therapy as a new treatment approach for Alzheimer’s disease

Dermatological Conditions

• Therapeutic effect of hyperbaric oxygen in psoriasis vulgaris: two case reports and a review of the

literature

• A favourable response to surgical intervention and hyperbaric oxygen therapy in pyoderma

gangrenosum (abstract)

• A prospective randomized controlled trial assessing the efficacy of adjunctive hyperbaric oxygen

therapy in the treatment of hidradenitis suppurative. (abstract)

Diabetes/Diabetic Wounds

• Can major amputation rates be decreased in diabetic foot ulcers with hyperbaric oxygen therapy?

• The Efficacy Of Hyperbaric Oxygen Therapy For The Treatment Of Diabetic Autonomic

Neuropathy

• IGF-1 Increases with Hyperbaric Oxygen Therapy and Promotes Wound Healing in Diabetic Foot Ulcers

• The role of oxygen-associated therapies for the healing of chronic wounds, particularly in patients

with diabetes(abstract)

• Treatment of diabetic foot infection with hyperbaric oxygen therapy (abstract)

• Hyperbaric oxygen therapy facilitates healing of chronic foot ulcers in patients with diabetes

• Potential benefits of hyperbaric oxygen therapy on atherosclerosis and glycaemic control in patients

with diabetic foot(abstract)

• Hyperbaric oxygen therapy for wound healing and limb salvage: a systematic review (abstract)

• Systematic review of the effectiveness of hyperbaric oxygenation therapy in the management of chronic diabetic foot ulcers (abstract)

• Diabetic hand infections and hyperbaric oxygen therapy. (abstract)

• Hyperbaric oxygen therapy (HBOT) suppresses biomarkers of cell stress and kidney injury in

diabetic mice. (abstract)

• Hyperbaric oxygen therapy reduces the risk of QTc interval prolongation in patients with diabetes

and hard-to-heal foot ulcers.

• Hyperbaric Oxygen Therapy Improves Glucose Homeostasis in Type 2 Diabetes Patients: A Likely

Involvement of the Carotid Bodies.

• Hyperbaric oxygen therapy increases insulin sensitivity in overweight men with and without type 2

diabetes.

Erectile Dysfunction

• The effect of hyperbaric oxygen therapy on erectile function recovery in a rat cavernous nerve injury

model (abstract)

• Hyperbaric oxygen therapy for recovery of erectile function after posterior urethral

reconstruction (abstract)

• Preclinical evidence for the benefits of penile rehabilitation therapy following nerve-sparing radical

prostatectomy (abstract)

Eye Disorders

• Hyperbaric oxygen therapy and age-related macular degeneration (abstract)

• Slowing the degenerative process, long lasting effect of hyperbaric oxygen therapy in retinitis

pigmentosa (pdf)

• Retinal artery occlusion: visual outcome after treatment with hyperbaric oxygen (abstract)

• Hyperbaric oxygen therapy and the eye (abstract) • Orbital entomophthoramycosis in an infant: recovery following surgical debridement, combination

antifungal therapy and use of hyperbaric oxygen

• Hyperbaric oxygen therapy in branch retinal artery occlusion in a 15-year-old boy with

methylenetetrahydrofolate reductase mutation (abstract)

• Efficacy of hyperbaric oxygen therapy in a young woman with idiopathic branch retinal artery

occlusion (abstract)

• Hyperbaric oxygen for the treatment of the rare combination of central retinal vein occlusion and

cilioretinal artery occlusion (abstract)

• Combined Central Retinal Artery and Vein Occlusion Associated with Factor V Leiden

Mutation and Treated with Hyperbaric Oxygen (abstract) • Reversibility of retinal ischemia due to central retinal artery occlusion by hyperbaric oxygen

• Central Retinal Artery Occlusion • The Efficacy of Hyperbaric Oxygen Therapy in the Treatment of Central Retinal Artery Occlusion

Fibromyalgia/Chronic Fatigue Syndrome

• Hyperbaric Oxygen Therapy Can Diminish Fibromyalgia Syndrome – Prospective Clinical Trial

• A new treatment modality for fibromyalgia syndrome: hyperbaric oxygen therapy. (abstract)

• A novel treatment modality for myofascial pain syndrome: hyperbaric oxygen therapy. (abstract)

• Hyperbaric oxygen therapy in chronic pain management. (abstract)

• Potential Benefits of Non-Pharmacological Therapies in Fibromyalgia

• Hyperbaric Therapy in Chronic Fatigue Syndrome (abstract)

• The efficacy of hyperbaric oxygen therapy in the management of chronic fatigue syndrome (abstract)

• Under Pressure Inc. Client Testimonials (video)

Gene Expression/Stem Cell Research/Mitochondrial Cytopathies

• The effect of bone marrow concentrate and hyperbaric oxygen therapy on bone repair.

• Hyperbaric oxygen therapy stimulates colonic stem cells and induces mucosal healing in patients

with refractory ulcerative colitis: a prospective case series

• POSITIVE EFFECTS OF HYPERBARIC OXYGENATION IN CERTAIN MITROCHONDRIAL

CYTOPATHIES

• Hyperbaric oxygen induces a cytoprotective and angiogenic response in human

microvascular endothelial cells.

• Hyperbaric oxygen treatment induces antioxidant gene expression (abstract) • Hyperbaric oxygenation enhances tranplanted cell graft and functional recovery in the infarct heart

Hearing Disorders

• Acute Tinnitus treated w/ HBOT

• Factors influencing the outcome of idiopathic sudden sensorineural hearing loss treated with

hyperbaric oxygen therapy (abstract)

• Hyperbaric oxygen therapy for acute noise-induced hearing loss: evaluation of different treatment regimens (abstract)

• The effect of hyperbaric oxygen therapy to different degree of hearing loss and types of threshold

curve in sudden deafness patients (abstract)

• Hyperbaric oxygen therapy seems to enhance recovery from acute acoustic trauma (abstract)

• Hyperbaric oxygen in the treatment of sudden deafness (abstract)

• Hyperbaric oxygen therapy (HBO2) as an adjunct in the treatment of idiopathic sudden

sensorineural hearing loss (ISSHL)–a case report on two patients. (abstract) • Management of sudden hearing loss with hyperbaric oxygen therapy (abstract)

• Hyperbaric oxygen as salvage treatment for idiopathic sudden sensorineural hearing loss.

• Comparison of two different steroid treatments with hyperbaric oxygen for idiopathic sudden

sensorineural hearing loss.

• The use of hyperbaric oxygen treatment for sudden sensorineural hearing loss in Europe (abstract)

• Concurrent hyperbaric oxygen therapy and intratympanic steroid application as salvage

therapy after severe sudden sensorineural hearing loss (abstract)

Hepatitis/Liver Disorders

• Clinical pathological study of treatment of chronic hepatitis with hyperbaric oxygenation. (abstract)

• Hyperbaric oxygen therapy in parenchymal liver disease. (abstract)

• Hyperbaric oxygen therapy reduces the toll-like receptor signaling pathway in multiple organ

failures. (abstract)

• Therapeutic effect of hyperbaric oxygen in hepatic artery thrombosis and functional cholestasis after orthotopic liver transplantation. (abstract)

• Beneficial effect of hyperbaric oxygenation on liver regeneration in cirrhosis. (abstract)

• Hyperbaric Oxygen Therapy in Liver Diseases

Lyme Disease

• Biofilms: hyperbaric?

• Biofilms and Chronic Infection

• LYMEPOLICYWONK: Misdiagnosis of Lyme disease as MS –MyLymeData Quick Bytes

• Horowitz MISIDS Lyme Questionnaire

• Comparison Chart of Lyme Disease and Co-infections Symptoms

• International Lyme and Associated Diseases Society • LymeDisease.org

• Hyperbaric Oxygenation for Lyme Vasculitis (pdf)

• Hyperbaric oxygen as a therapy of Bell’s palsy (abstract)

• Lyme disease and hyperbarics (video)

• Hyperbaric oxygen therapy as an effective adjunctive treatment for chronic Lyme disease (article)

• Under Pressure Inc. Client Testimonials (video)

• TICK TESTING

• Lyme Bacteria Survive a 28-day Course of Antibiotics

Miscellaneous

• Hyperbaric Oxygen for Bacteria, Viruses, & Yeast

• Improvement of attention span and reaction time with hyperbaric oxygen treatment in patients with toxic injury due to mold exposure

• Effects of hyperbaric oxygen on aggressive periodontitis and subgingival anaerobes in Chinese

patients

• Effect of hyperbaric oxygen therapy on patients with herpes zoster

• Orbital entomophthoramycosis in an infant: recovery following surgical debridement, combination

antifungal therapy and use of hyperbaric oxygeI

• Hyperbaric oxygen therapy in China

• Principles and practice of hyperbaric medicine: a medical practitioner’s primer

• Hyperbaric oxygen preconditioning protects skin from UV-A damage

• HBOT for Parkinson’s (video)

• HBOT and Alzheimer’s (video) • Dr. Paul Harch Hyperbarics Inc. HBOT Treatments (video)

• Hyperbaric oxygen treatment induces antioxidant gene expression

Migraine/Cluster/Tension Headaches

• Hyper- or normobaric oxygen therapy to treat migraine and cluster headache pain. Cochrane

review (abstract)

• Normobaric and hyperbaric oxygen therapy for migraine and cluster headache (abstract)

• Hyperbaric oxygen in the treatment of patients with cerebral stroke, brain trauma, and neurologic

disease (abstract)

MS/LS/Myasthenia Gravis

• Repetitive long-term hyperbaric oxygen treatment (HBOT) administered after experimental

traumatic brain injury in rats induces significant remyelination and a recovery of sensorimotor

function.

• Long-term hyperbaric oxygenation retards progression in multiple sclerosis patients • MS National Therapy Centres

• HBOT, Stem Cells, and Multiple Sclerosis (M.S.) (video)

• Sara’s Garden Hyperbaric Oxygen Therapy (HBOT) Testimonial – Amanda (M.S.) (video)

• HBOT AND MULTIPLE SCLEROSIS – HYPERBARIC OXYGEN THERAPY (video)

• Amyotrophic Lateral Sclerosis

• Myasthenia Gravis

Nerve Pain/Injuries

• Successful Treatment of Lower Limb Complex Regional Pain Syndrome following Three Weeks of

Hyperbaric Oxygen Therapy.

• Hyperbaric oxygen treatment decreases pain in two nerve injury models (pdf)

• Effects of hyperbaric oxygen therapy on facial nerve regeneration (abstract)

• Hyperbaric oxygen as a therapy of Bell’s palsy (abstract)

• Hyperbaric Oxygen Treatment for Reflex Sympathetic Dystrophy Syndrome RSD (video)

• Effect of hyperbaric oxygen therapy on patients with herpes zoster

Neuropathies

• HBOT for Neuropathy

• The effectiveness of intermittent hyperbaric oxygen in relieving drug-induced HIV-associated neuropathy.

• The Efficacy Of Hyperbaric Oxygen Therapy For The Treatment Of Diabetic Autonomic Neuropathy

• Hyperbaric oxygenation therapy alleviates chronic constrictive injury-induced neuropathic pain and

reduces tumor necrosis factor-alpha production.

Non-Healing Wounds and Sores

• Hyperbaric oxygen for chronic wounds (abstract)

• Hyperbaric Oxygen Therapy: Solution for Difficult to Heal Acute Wounds? Systematic Review

• Evaluation of the efficacy of hyperbaric oxygen therapy in the management of chronic nonhealing

ulcer and role of periwound transcutaneous oximetry as a predictor of wound healing response: A

randomized prospective controlled trial

• Improvement of ischemic non-healing wounds following hyperoxygenation: the experience at Rambam-Elisha Hyperbaric Center in Israel, 1998-2007 (abstract)

• Necrotizing fasciitis: literature review of contemporary strategies for diagnosing and management

with three case reports: torso, abdominal wall, upper and lower limbs

• Hyperbaric oxygen induces a cytoprotective and angiogenic response in human microvascular

endothelial cells

• The efficacy of hyperbaric oxygen therapy in improving the quality of life in patients with problem

wounds (abstract)

• Ischemic scleroderma wounds successfully treated with hyperbaric oxygen therapy (abstract)

• Hyperbaric Oxygen Therapy Mediates Increased Nitric Oxide Production Associated With Wound

Healing: A Preliminary Study • Hyperbaric oxygen and wound healing

• The effect of bone marrow concentrate and hyperbaric oxygen therapy on bone repair.

• Hyperbaric oxygen therapy accelerates osteoblast differentiation and promotes bone formation.

• Hyperbaric Oxygen Therapy and Wound Care (video)

• Hyperbaric Oxygen Therapy: Wound Healing & Anti-Aging – Scott Sherr (September 2014) (video)

• Necrotising soft tissue infections: the effect of hyperbaric oxygen on mortality (abstract)

• Hyperbaric oxygen therapy for chronic ulcers in systemic sclerosis-case series

Osteomyelitis

• Hyperbaric Oxygen for Osteomyelitis in a Compromised Host

• Hyperbaric oxygen therapy for wound healing and limb salvage: a systematic review (abstract)

Parkinson’s Disease

• HBOT for Parkinson’s

• Parkinson’s Case Studies HBOT

• Parkinson’s Disease Responding To Hyperbaric Oxygen Therapy

PTSD

• Phase I Study of Low-Pressure Hyperbaric Oxygen Therapy For Blast-Induced Post-Concussion

Syndrome and Post-Traumatic Stress Disorder

• Hyperbaric oxygen ameliorates worsening signs and symptoms of post-traumatic stress disorder

• More HBOT for PTSD Vets through the IHMF’s NBIRR study (video)

• U.S. Veteran Pilot Trail LSU IRB #7051 HBOT in TBI/PTSD Preliminary Data

• Dr. Paul Harch treats Iraq vets for TBI/PTSD with Hyperbaric Oxygen Therapy (HBOT), Part

1 (video)

• Dr. Paul Harch treats Iraq vets for TBI/PTSD with Hyperbaric Oxygen Therapy (HBOT), Part 2 (video)

• Low pressure hyperbaric oxygen therapy and SPECT brain imaging in the treatment of

blast-induced chronic traumatic brain injury (post-concussion syndrome) and post traumatic

stress disorder: a case report

• Case Control Study: hyperbaric oxygen treatment of mild traumatic brain injury persistent

post-concussion syndrome and post traumatic stress disorder

Sepsis

• Hyperbaric oxygen therapy in a patient with autosomal dominant polycystic kidney disease with a

perinephritic abscess (abstract)

Spinal Cord Injury

• Attenuating experimental spinal cord injury by hyperbaric oxygen: stimulating production of

vasculoendothelial and glial cell line-derived neurotrophic growth factors and interleukin-10 (abstract)

• Hyperbaric oxygen induces endogenous neural stem cells to proliferate and differentiate in hypoxic-

ischemic brain damage in neonatal rats (abstract)

• Hyperbaric oxygen therapy improves local microenvironment after spinal cord injury (abstract)

Stroke/Brain Aneurysm

• Reflections on the neurotherapeutic effects of hyperbaric oxygen, Expert Review of

Neurotherapeutics, Informa Healthcare

• Hyperbaric Oxygen Therapy for Individuals with Neurological Dysfunction

• Hyperbaric Oxygen Induces Late Neuroplasticity in Post Stroke Patients

• Hyperbaric Oxygen Induces Late Neuroplasticity in Post Stroke Patients (video)

• Decades-old stroke damage reversible with oxygen therapy, say researchers (video) • Hyperbaric Oxygen for Cerebral Vasospasm and Brain Injury Following Subarachnoid Hemorrhage

• Effects of Repetitive Hyperbaric Oxygen Treatment in Patients with Acute Cerebral Infarction: A

Pilot Study

• Hyperbaric oxygen therapy promotes neurogenesis: where do we stand?

• Hyperbaric oxygen for stroke treatment (editorial)

• Hyperbaric oxygen induces endogenous neural stem cells to proliferate and differentiate in hypoxic-

ischemic brain damage in neonatal rats (abstract)

• Stem cell mobilization by hyperbaric oxygen (pdf)

• Hyperbaric oxygen in the treatment of patients with cerebral stroke, brain trauma, and neurologic disease (abstract)

• Delayed hyperbaric oxygen therapy induces cell proliferation through stabilization of cAMP

responsive element binding protein in the rat model of MCAo-induced ischemic brain

injury (abstract)

• Hyperbaric oxygen can induce neuroplasticity and improve cognitive functions of patients suffering

from anoxic brain damage.

• Recovery From Stroke with Hyperbaric Oxygen Therapy (HBOT) (video)

• Stroke And Hyperbaric Chambers (video)

• A Dual Role for Hyperbaric Oxygen in Stroke Neuroprotection: Preconditioning of the Brain and

Stem Cells

Surgical Sites with Grafts or Flaps

• Does hyperbaric oxygen administration before or after irradiation decrease side effects of

irradiation on implant sites?(abstract)

• The effect of hyperbaric oxygen on compromised grafts and flaps (abstract)

• Evaluation of hyperbaric oxygen therapy for free flaps using planar optical oxygen sensors.

Preliminary results(abstract)

• The influence of hyperbaric oxygen treatment on the healing of experimental defects filled with

different bone graft substitutes

• Fasciotomy closure using simultaneous vacuum-assisted closure and hyperbaric oxygen (abstract)

• Is Tracheal Transplantation Possible With Cryopreserved Tracheal Allograft and Hyperbaric

Oxygen Therapy? An Experimental Study.

• The Science of Hyperbaric Oxygen for Flaps and Grafts (abstract)

Surgery (pre & post) Orthopedic/Plastic/Reconstruction/Resection/Stereotactic

Radiosurgery

• Hyperbaric oxygen preconditioning protects skin from UV-A damage (abstract)

• Safety and efficacy of early postoperative hyperbaric oxygen therapy with restriction of transfusions

in patients with HCC who have undergone partial hepatectomy (abstract) • Hyperbaric oxygen induces a cytoprotective and angiogenic response in human microvascular

endothelial cells

• Hyperbaric oxygen therapy for treating acute surgical and traumatic wounds (abstract)

• Prevention of avascular necrosis in displaced talar neck fractures by hyperbaric oxygenation

therapy: a dual case report (abstract)

• Stem cell mobilization by hyperbaric oxygen (pdf)

• Hyperbaric oxygen therapy and liver transplantation (abstract)

• Hyperbaric oxygen in the treatment of a radiosurgical complication: technical case report (abstract)

• Hyperbaric oxygen therapy for treatment of adverse radiation effects after stereotactic radiosurgery

of arteriovenous malformations: case report and review of literature (abstract) • Hyperbaric oxygen preconditioning reduces postoperative brain edema and improves neurological

outcomes after surgical brain injury (abstract)

• Usefulness of hyperbaric oxygen in the treatment of radionecrosis and symptomatic brain edema

after LINAC radiosurgery (abstract)

• Hyperbaric oxygen therapy facilitates surgery on complex open elbow injuries: preliminary

results (abstract)

• Hyperbaric oxygen in the treatment of postoperative infections in paediatric patients with

neuromuscular spine deformity

• Hyperbaric oxygen and wound healing • Hyperbaric Oxygen Preconditioning-Induced Neuroprotection Against Ischemic Stroke

• Does hyperbaric oxygen therapy prevent airway anastomosis from breakdown?

• Efficiency of Hyperbaric Oxygen Therapy in Iatrogenic Spinal Infections (abstract)

• Hyperbaric oxygen therapy as an alternative to surgery for non-healing pharyngocutaneous

fistula (abstract)

• Can hyperbaric oxygen be used to prevent deep infections in neuro-muscular scoliosis surgery?

Traumatic/Chronic Brain/Head Injury

• Phase I Study of Low-Pressure Hyperbaric Oxygen Therapy For Blast-Induced Post-Concussion

Syndrome and Post-Traumatic Stress Disorder

• Hyperbaric oxygen: B-level evidence in mild traumatic brain injury clinical trials.

• Repetitive long-term hyperbaric oxygen treatment (HBOT) administered after experimental traumatic brain injury in rats induces significant remyelination and a recovery of sensorimotor

function.

• Hyperbaric oxygen therapy and cerebral ischemia: neuroprotective mechanisms

• Improvement of attention span and reaction time with hyperbaric oxygen treatment in patients with

toxic injury due to mold exposure

• Reflections on the neurotherapeutic effects of hyperbaric oxygen, Expert Review of

Neurotherapeutics, Informa Healthcare

• Hyperbaric oxygen therapy ameliorates local brain metabolism, brain edema and inflammatory

response

• Hyperbaric Oxygen Therapy Can Improve Post Concussion Syndrome Years after Mild Traumatic Brain Injury – Randomized Prospective Trial

• Hyperbaric Oxygen Therapy for Individuals with Neurological Dysfunction

• Role of hyperbaric oxygen therapy in severe head injury in children

• Hyperbaric oxygen therapy for traumatic brain injury

• Hyperbaric Oxygen Treatment (HBOT) for TBI/PTS (video) • Improving neuropsychological function after chronic brain injury with hyperbaric oxygen (abstract)

• Use of hyperbaric oxygen in traumatic brain injury: Retrospective analysis of data of 20 patients

treated at a tertiary care centre (abstract)

• Hyperbaric oxygen therapy (1.5 ATA) in treating sports related TBI/CTE: two case reports

• Neuroprotective effect of hyperbaric oxygen therapy in brain injury is mediated by preservation of

mitochondrial membrane properties (abstract)

• Improvement of attention span and reaction time with hyperbaric oxygen treatment in patients with

toxic injury due to mold exposure

• Hyperbaric oxygen therapy promotes neurogenesis: where do we stand?

• Hyperbaric Oxygen Therapy for Reduction of Secondary Brain Damage in Head Injury: An Animal Model of Brain Contusion

• Hyperbaric oxygen induces endogenous neural stem cells to proliferate and differentiate in hypoxic-

ischemic brain damage in neonatal rats (abstract)

• U.S. Veteran Pilot Trail LSU IRB #7051 HBOT in TBI/PTSD Preliminary Data

• Hyperbaric oxygen in the treatment of patients with cerebral stroke, brain trauma, and neurologic

disease (abstract)

• Delayed hyperbaric oxygen therapy induces cell proliferation through stabilization of cAMP

responsive element binding protein in the rat model of MCAo-induced ischemic brain

injury (abstract) • Microglial activation induced by traumatic brain injury is suppressed by postinjury treatment with

hyperbaric oxygen therapy (abstract)

• Dr. Paul Harch treats Iraq vets for TBI/PTSD with Hyperbaric Oxygen Therapy (HBOT), Part

1 (video)

• Dr. Paul Harch treats Iraq vets for TBI/PTSD with Hyperbaric Oxygen Therapy (HBOT), Part

2 (video)

• Overcoming Brain Injury – Juan’s Story (video)

• Sara’s Garden Hyperbaric Oxygen Therapy (HBOT) Testimonial – Aubree (TBI) (video)

• Hyperbaric Oxygen Therapy-Bryan Murphy (video)

• The Courage to Come Back: A story of hope. (video) • Hyperbaric oxygen may induce angiogenesis in patients suffering from prolonged post-concussion

syndrome due to traumatic brain injury.

• Clinical results in brain injury trials using HBO2 therapy: Another perspective.

• Hyperbaric Oxygen in Mild TBI: Conflicting Civilian and Department of Defense Studies Explained.

• Clinical research on postoperative efficacy and related factors of early simulation hyperbaric oxygen

therapy for severe craniocerebral injury (abstract)

• Hyperbaric oxygen may induce angiogenesis in patients suffering from prolonged post-concussion

syndrome due to traumatic brain injury (abstract)

• Hyperbaric oxygen can induce neuroplasticity and improve cognitive functions of patients suffering

from anoxic brain damage. • Hyperbaric oxygen in chronic traumatic brain injury: oxygen, pressure, and gene therapy.

• Repetitive long-term hyperbaric oxygen treatment (HBOT) administered after experimental

traumatic brain injury

• Hyperbaric Oxygen Therapy Can Induce Angiogenesis and Regeneration of Nerve Fibers in

Traumatic Brain Injury Patients

• Case Control Study: hyperbaric oxygen treatment of mild traumatic brain injury persistent post-

concussion syndrome and post traumatic stress disorder