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Research topics Key words ResearcherReseach Field Field of expertise Research themes underconsideration

Chemicalpharmaceutical science

Cycloaddition of Allenic CompoundsDevelopment of asymmetric catalystsMetal-catalyzed selective reaction

organic chemistry synthetic chemistry KITAGAKI Shinji


Isolation and Structural Analysis of Biologically Active Natural ProductsStudy of natural products chemistry forinhibitors of metabolic enzymesSearch for functional substances using the antistress-scienceevaluation system

Natural Product Chemistry Pharmacognosy OTA Tomihisa


Isolation of active constituents from natural material that modulatemucosal immune responseComprehensive analysis for genetic profiles on the pharmacologicalactivity of Kampo medicine.

Pharmacognosy, Natural Products, Pharmacology TAKANO Fumihide


Development of ChAT mapping agent forAlzheimer\'s disease early diagnosis

Study on Syntheses of Radiopharmaceutical for cerebral nervefunction diagnosisDevelopment of a high sensitive evaluation of internal radiationexposure

Brain,moleculerimaging,radiation SHIBA Kazuhiro


Development of Highly Stereoselective Reactions Based onOrganometallics and Their Application to Syntheses of BiologicallyActive Compound

organometallic chemistry, synthetic organic chemistry, naturalproduct chemistry MUKAI Chisato


Study on Asymmetric Reduction of Symmetric Diketones with Baker'sYeastStudy on Asymmetric Reactions using Optically ActiveOrganoselenium ReagentsStudy on Oxidative Radical Cyclization using Polymer-supportedMn(III) reagentStudy on Ce(IV)-catalyzed asymmetric oxidative radical reaction

Synthetic Organic Chemistry UCHIYAMAMasahiko


Development of New Organic ReactionsTotal Synthesis of Bioactive Compounds Organic Reactions, Organic Synthesis MATSUO Junichi


Development of molecular catalysts and new synthetic methods basedon biofunctionsDiscovery of effective methods for chemical modification ofbiomolecules available for elucidation and exploring their function

KUNISHIMAMunetaka

Physical pharmaceuticalscience

Transporter-mediated drug uptake andeffluxDrug metabolism and disposition usinggene-knockout animals

Transporter-mediated disposition and delivery of therapeutic agentsRegulation mechanisms of localization and function of xenobiotictransportersPharmacokinetics and delivery of biologically active proteins andmacromolecules

Pharmacokinetics, Pharmacotherapeutics, membranepermeation, transporter, protein-protein interaction KATO Yukio

Physical pharmaceuticalscience the development of radiopharmaceuticals Radiopharmaceutical,Cancer,Bone OGAWA Kazuma

Medical, D

ental, and Pharmaceutical Science

Pharmaceutical Science


Biological systempharmaceutical science Collaboration among industry, academia and government WATANABE

Yoshinari

Biological systempharmaceutical science Regulation of T cell activation T cell activation, Lymphocyte proliferation, Immune regulation INOBE Manabu

Biological systempharmaceutical science





Analysis of lysosomal membrane fusionStudy on autophagyMechanism of Neuro-regeneration

Clinical Pharmacy.Biochemistry.Neurobiology ARAI Kunizo

Biological systempharmaceutical science Research on anti-cancer drugs targeting

cellular responses to DNA damage

Molecular analysis of cellular responses to DNA damageFunctional analysis of DDB complex in cellular responses to DNAdamageEstablishment and application of detection systems for UV-inducedDNA damage

DNA repair Hereditary disorder Cancer Signal transductionCellular response Ultraviolet light

MATSUNAGATsukasa


Study of therapeutic drug monitoringDevelopment of clinical pharmacyeducation with IT

Clinical pharmaceutical or phamracokinetic study for drug therapeuticsand adverse event monittoringEstablishment of detection method of counterfeit drugsStudy and application of therapeutic drug monitoringAssistance for pharmacist performing pharmaceuitcal care by scientificapproach

Clinical Pharmacokinetics Clinical Pharmacology ClinicalPharmacy Therapeutic Drug Monitoring PharmaceuticsPharmacuticals

MATSUSHITA Ryo

Drug developmentchemistry

Development of Highly Stereoselective Reactions Based onOrganometallics and Their Application to Syntheses of BiologicallyActive Compound

organometallic chemistry, synthetic organic chemistry, naturalproduct chemistry MUKAI Chisato

Environmentalpharmaceutical science

Simple Analysis Method for Trace ofEndocrine Disruptors by LuminescenceDetecti

Spectroscopic and Photochemical Characteristics of EndocrineDisruptorsWater Treatment by Hydrochlorous Acid with Bactericidal andCoagulating AbilitieDegradation of Toxic Chemical Compounds by Visible-Light DrivenPhotocatalysts

Laser Spectroscopy Photochromism Transient AbsorptionEndocrine Disrupting Chemicals Persistent Organic PollutantsFluorescence-Phosphorescence Photocatalyst EndocrineDisrupting Chemicals Solar Energy

TOKUMURAKunihiro


Development of Determination Methods forUnregulated Hazardous PollutantsBiological Effects of Diesel ExhaustParticulates

Study on Mutagenic Polycyclic Aromatic Hydrocarbons :Environmental Behaviors and Biological EffectsStudy on New Endocrine Disrupting Chemicals in EnvironmentsDevelopment of New Photometric Detection/Liquid Chromatographyfor Environmental Chemicals

Polycyclic Aromatic Hydrocarbon HAYAKAWAKazuichi


Study for the evaluation of the exposure to polycyclic aromatichydrocarbons Polycyclic aromatic hydrocarbons, biomarkmer TORIBA Akira

Medical, D





Study on access ,quality rational use of and medicines in developingcountryStudy on Drug Management and PolicyStudy on HIV/AIDS Measures

Counterfeit Medicines, Access Quality, Rational Use of Medicines,HIV/AIDS KIMURA Kazuko

Clinical pharmaceuticalscience





Analysis of lysosomal membrane fusionStudy on autophagyMechanism of Neuro-regeneration

Clinical Pharmacy.Biochemistry.Neurobiology ARAI Kunizo

Clinical pharmaceuticalscience Roles of membrane transporters in drug action transporter,drug absorption and disposition TAMAI Ikumi

Clinical pharmaceuticalscience Gene dyagnosis for drug sensitivity

Development of Drug Delivery System for BoneStudies on development of new cancer chemotherapyDrug interactionDevelopment of Personal Drug Therapy

Molecular pharmacology Clinical Pharmacy MIYAMOTO Kenichi


Human UDP-GlucuronosyltransferaseGenetic polymorphisms of Drug-metabolizing enzymesRegulation of drug metabolizing enzymes

Drug metabolism, interindividual difference, geneticpolymorphisms NAKAJIMA Miki


Clinical Pharmacy, Pharmacy Sciences, Clinical PharmacyEducation OYANAGI Kazuo


Study of therapeutic drug monitoringDevelopment of clinical pharmacyeducation with IT

Clinical pharmaceutical or phamracokinetic study for drug therapeuticsand adverse event monittoringEstablishment of detection method of counterfeit drugsStudy and application of therapeutic drug monitoringAssistance for pharmacist performing pharmaceuitcal care by scientificapproach

Clinical Pharmacokinetics Clinical Pharmacology ClinicalPharmacy Therapeutic Drug Monitoring PharmaceuticsPharmacuticals

MATSUSHITA Ryo


Development of order-made pharmacotherapyApproach to scientific evidence-based drug therapyDevelopmento of age-dependent pharmacokinetics

Clinical Pharmacy Pharmaceutical Care Personalized MedicinePharmaceutical Care Communication PharmaceuticalCommunication pharmacokinetics therapeutic drug monitoringdrug interaction

ISHIZAKI Junko


clarification of pathology and search for the new treatment ofdisseminated intravascular coagulationSurveillance and development of preventive method forchemotherapy-induced adverse drug reaction

cancer chemotherapy, pharmaceutical care SUGA Yukio

Clinical pharmaceuticalscience Transporters and Drug Disposition Elucidation of molecular mechanism of cancer cell-specific

protoporphyrin IX accumulation induced by 5-aminolevulinic acidTransporter, Pharmacokinetics, Molecular Biology,Chemotherapy, Cancer, Gene Expression, Signal Transduction NAKANISHI Takeo

Medical, D



Research topics Key words ResearcherReseach Field Field of expertise Research themes underconsiderationPharm

aceutical

Science


Genetic polymorphisms of Drug Metabolizing enzymesTranscriptional regulatron and induction mechanism of drugmetabolizing enzymesEvaluation and projection of toxicity and safety of drugs andenvironmental chemical substances

Drug metabolism, Molecular Pharmacology, Toxicology,Cytochrome P450 YOKOI Tsuyoshi

Generalanatomy(includeshistology/embryology)

Localization of biological active proteins inliving cells and tissues

Histochemical study on signaling in development, growth anddifferentiation histochemistry, cell, tissue, differentiation ISEKI Shoichi


Histological Study on Peripheral Nervous SystemHistological analyze of the proliferation and differentiation of rodentsubmandibular gland cells.

anatomy histology embryology YAMAMOTO Miyuki


Study of Growth Factors in the Testis and EpididymisStudy of Adhesion Molecule in the Spermatogenesis Anatomy WAKAYAMA

Tomohiko


Functional analysis of Jmjd5, a candidate cancer gene identified byretroviral insertional mutagenesis ISHIMURA Akihiko

General physiology

Mechanism of vascular smooth muscle contractionStudies of the physiological and pathological roles of the lipid mediatorsphingosine-1-phosphateStudies of the physiological and pathological roles of the lipid kinasePI3-kinase

Cell signaling, Vessel, Cancer TAKUWA Yo

General physiology Neural mechanisms of circadian rhythmsNeural mechanisms underlying sleep/wake regulation circadian rhythm, feeding, hypothalamus MIEDA Michihiro

General physiology

Identification and characterization about physiological functions ofnovel neuropeptidesRegulatory Mechanisms of Sleep/wakefulness StatesFeeding behavior and energy homeostasis

hypothalamus, limbic system, neuropeptide SAKURAI Takeshi

General physiologyThermoregulationSignal transductionRegulation of cell migration

SUGIMOTONaotoshi

General physiology Regulation of contraction of vascular smooth muscle cells bymechanical stimulus

Angiogenesis, Cardiovascular remodeling, contruction-relaxationSmooth muscle cell, Signal transduction YOSHIOKA Kazuaki

General physiology The influence of autonomic nervous system with DPP-4 inhibitor indiabetes

circulation, autonomic nervous system, muscle sympathetic nerveactivity, diabetes mellitus

KOBAYASHIDaisuke

Medical, D


Fundamental M

edicine


Environmentalphysiology(includessportsmedicine/nutritionalphysiology)

Floor translation system for training ofequilibrium functionSystem for enhancing and causing brainactivation with postural changeEvaluation system of muscle activity andposture for backache prevention

Dynamic postural control and brain activityBrain activation by movement and posuturePositional perception of standing posture

postural control, brain activation, evoked brain potential FUJIWARA Katsuo


Research for reduction of exercise-inducedoxidative stressDevelopment of training and conditioningmethods for competitive sports

Molecular regulation of oxygen transport to muscle tissue andmitochondria bioenergetics during exerciseMolecular determinants for selectivity of substrates in skeletal muscleduring exerciseExercise induced free radical, oxidative stress and regeneration ofmyocytes

mitochondoria, free radical, oxidative stress, redox, skeletalmuscle physilogy, oxidative metabolism, exercise and sportphysilogy

MASUDA Kazumi


Study of the physical activity contentsusing the heart rate monitouringEffects of drug and nutriment on skeletalmuscles, heart, and bonesAnalyasis of affecting factors on muscles

Comparative Study of myosin isozyme and muscle fiber compositionDevelopment of assessing method for physical activity with HREffects of doping drugs on striated muscles

Exercise Physiology Physical fitness muscle physiology KITAURA Takashi


Automatized levels of upper and lower limb movementsDevelopment of parallel control of posture and hand and fingermovement during floor motion repetitive loading

automatization TOYAMA Hiroshi

General pharmacology Durg discoveryFunctional analysis of food chemicals

Regulation and function of heme catabolismHypoxia responseFunctional analysis of food chemicals

heme oxygenase, hypoxia response OGAWA Kazuhiro

General pharmacology

Identification and characterization about physiological functions ofnovel neuropeptidesRegulatory Mechanisms of Sleep/wakefulness StatesFeeding behavior and energy homeostasis

hypothalamus, limbic system, neuropeptide SAKURAI Takeshi

General pharmacologyPharmacokineticsPrediction of difficult intubationPalliative Care

Anesthesiology YAMAMOTO Ken

General pharmacology

Study of the physical activity contentsusing the heart rate monitouringEffects of drug and nutriment on skeletalmuscles, heart, and bonesAnalyasis of affecting factors on muscles

Comparative Study of myosin isozyme and muscle fiber compositionDevelopment of assessing method for physical activity with HREffects of doping drugs on striated muscles

Exercise Physiology Physical fitness muscle physiology KITAURA Takashi

General medicalchemistry

Identification of novel molecular targetsthat interact with cancer genes

Identification of novel cancer genes using retroviral insertionalmutagenesis Tumor virus, Oncogene, Genome informatics SUZUKI Takeshi


pathogenesis and prevention/treatment ofdiabetic angiopathy

Molecular Basis of the Alzheimer's diseaseSignal transduction through protein phosphatasesMolecular mechanism of diabetic angiopathy

Diabetic Angiopathy, Advanced Glycation Endproducts, Receptorfor advanced glycation endproducts, RAGE, Angiogenesis,Alzheimer's disease,

WATANABE Takuo

Fundamental M

edicine

Medical, D




Role of endogenous secretory RAGE(esRAGE) in human diseasesanimal models of diabetic nephropathyPrevention of development of diabeticcomplications

Molecular mechanism for development of diabetic vascularcomplicationsInnate immunityInflammation in obesity

Diabetes, Diabetic vascular complications, Immunity YAMAMOTOYasuhiko

General medicalchemistry Analysis of the mechanism of diabetes complecation development biochemistry, molecular biology, diabetes MUNESUE Seiichi


DNA tumor Virustumor MetastasisMolecules related to cancer metastasis

Molecular Oncology Molecular Virology Tumor Metastasis MatrixMetalloproteinase Gene SATO Hiroshi


Roles of ADAMTS family genes in organogenesis and organ functionExtracellular matrix metabolism and disordersExtracellular matrix metabolism and cancer invasion-metastasis

KUNO Koji


Tissue regeneration mediated by HGF-Met. Therapeutic application ofHGF. Anti-cancer approach with NK4.Drug discovery targeting HGF-Met.Regulation of #-D cancer invasion and epithelial morphogenesis.Tissue regeneration mediated by HGF-Met. Therapeutic application ofHGF. Anti-cancer approach with NK4.

Growth Factor, Metastasis, Angiogenesis, HGF, NK4 MATSUMOTO Kunio

General medicalchemistry Molecular pharmacology of bioactive lipids Molecular Pharmacology YOSHIMOTO

Tanihiro


AngiogenesisDiabetic angiopathyFunctional genomics

vascular biology, diabetes YAMAMOTO Hiroshi

Pathological medicalchemistry

Durg discoveryFunctional analysis of food chemicals

Regulation and function of heme catabolismHypoxia responseFunctional analysis of food chemicals

heme oxygenase, hypoxia response OGAWA Kazuhiro


Undifferenticated property maintenance mechanism of embryo-stemcells (ES cells, self-replication, STAT3) YOKOTA Takashi


Screening of genes expressed selectivelyin chronic liver injuryAnti-tumor therapy targeting chemokinesAnti-inflammatory therapy targetingchemokinesDevelopment of a novel type of anti-cancerdrug targeting a novel serine/threoninekinase, Pim-3

Study on pro-inflammatory cytokines and chemokines in tumordevelopment and progressionElucidaiton on the roles of Pim kinases in cancer development andprogressionStudy on roles of pro-inflammatory cytokines and chemokines iniflammation.

Pro-inflammatory cytokines MUKAIDA Naofumi

Medical, D


Fundamental M

edicine



pathogenesis and prevention/treatment ofdiabetic angiopathy

Molecular Basis of the Alzheimer's diseaseSignal transduction through protein phosphatasesMolecular mechanism of diabetic angiopathy

Diabetic Angiopathy, Advanced Glycation Endproducts, Receptorfor advanced glycation endproducts, RAGE, Angiogenesis,Alzheimer's disease,

WATANABE Takuo


Role of endogenous secretory RAGE(esRAGE) in human diseasesanimal models of diabetic nephropathyPrevention of development of diabeticcomplications

Molecular mechanism for development of diabetic vascularcomplicationsInnate immunityInflammation in obesity

Diabetes, Diabetic vascular complications, Immunity YAMAMOTOYasuhiko


DNA tumor Virustumor MetastasisMolecules related to cancer metastasis

Molecular Oncology Molecular Virology Tumor Metastasis MatrixMetalloproteinase Gene SATO Hiroshi

Pathological medicalchemistry Cellular Signal transduction pathways involved in stress response Radiation Biol. and Toxicology Cell Biology Molecular Biology YAMAMOTO Kenichi


Molecular Diagnosis of Colorectal CancerSerial Analysis of Gene Expression inStomach Cancer

Molecular oncology of gastrointestinal cancerSurgical oncology for gastrointestinal cancerEstablishment of tissue material resources of human gastrointestinalcancer

Gastrointestinal oncology, Surgical and molecular oncology MINAMOTOToshinari

Pathological medicalchemistry Study on the NLR family

Study on Immune Regulation by Fas LigandStudy on the molecular mechanisms of cell death and inflammationStudy on the Apoptosis of Cancer Cells.

Immunology, Apoptosis, Fas ligand, Inflammation, Cancer SUDA Takashi


Study on physiological role of Fas ligandStudy on Physiological Connection between Apoptosis andInflammation

IMAMURA Ryu

Pathological medicalchemistry Study on Tumor Cell Invasion TAKINO Takahisa

Pathological medicalchemistry study on DNA damage repair KOBAYASHI

Masahiko


Molecular mechanism of tumorigenesis, progression, metastasis andcancer stem cellsTumor suppressor function of RECKAnalysis of Rb-Ras pathway

Molecular Oncology, Molecular Biology, Cancer Genetics TAKAHASHI Chiaki


function of novel physiological active lipid,molecular mechanisms ofvascular contraction lipid mediater, smooth muscle contraction OKAMOTO Yasuo

Medical, D


Fundamental M

edicine



Cooperation of Wnt signaling and COX-2 pathway in gastrointeitinaltumorigenesisInflammatory host responses in gastrointestinal tumorigenesis

inflammation and cancer, genetics, mouse model OSHIMA Masanobu

Pathological medicalchemistry Molecular pharmacology of bioactive lipids Molecular Pharmacology YOSHIMOTO

Tanihiro


AngiogenesisDiabetic angiopathyFunctional genomics

vascular biology, diabetes YAMAMOTO Hiroshi

Human genetics Comprehensive genetic analysis of congenital anomalies, geneticfixation with regard to autistic disorders congenital malformation syndro NIIDA Yo

Human pathology

Pathology of liver tumorsPathology of bile ductsPathological study of autoimmune liverdeseasespathology of liver disease

Pathology and pathogenesis of primary biliary cirrhosisPathogenesis of hepatolithiasisPathogenesis of abnormal portalvenous blood flow

Hominal Pathology, Liver Pathology, Immunopathology NAKANUMA Yasuni

Human pathology Pathology of cancer oncology OI Akishi

Human pathology

Practical studies on medico-legal diagnosisForensic toxicological studies on rapid screening for illicit drugs andpoisonsMedico-legal studies on minute biological specimens by moleculargenetic procedures

injury, biological material, postmortem change, forensic expertopinion OHSHIMA Tohru

Human pathology Pathology and Pathogenesis ofhepatobiliary disease

Immunohistochemical investigation of outbreak and development ofintrahepatic bile duct cancer coexisting with intrahepatic lithiasisMucin core proteins in Hepatobiliary diseasePathogenesis of Primary biliary cirrhosis.

Pathology of the liver SASAKI Motoko

Human pathology Vascular Fragility, Forensic Pathology, Platelet ZUKA Masahiko

Human pathologyPathology of the liverImmunology of the liverLiver cancer

Liver, Pathology, Immunology HARADA Kenichi

Human pathology Pathomorphology of hepatobiliary system diseasesMolecular biology SATO Yasunori

Human pathologyDevelopment of hormone-drug releasesystem via supramolecular dissociation

DNA analysis in the study for carcinogenesis of Endometrial cancerand gene therapyHuman papilloma analysis in the carcinogenesis of uterine cervicalcancerGene therapy for ovarian Cancer

Molecular pathology in gynecologic field Auti-Cancenchemotherapy in Gynecologic field Cell aging and carcinogenesis INOUE Masaki

Medical, D


Fundamental M

edicine


Human pathology Molecular Mechanisms regulatingTherapeutic-resistant CML stem cells

Therapeutic Resistance in Cancer Stem CellsMaintenance of Self-renewal Ability in Hematopoietic Stem Cells

Cancer stem cells, Cancer-microenvironment, Hematopoieticstem cells NAKA Kazuhito

Experimental pathology




Experimental pathology




Experimental pathologyPathology of the liverImmunology of the liverLiver cancer


Experimental pathology Study for genomics in liverCancer ResearchLiver metabolism and systemic illnessHepatitis Virus

Experimental Pathology, Virology, Cancer, Liver KANEKO Shuichi

Experimental pathologyRoles of ADAMTS family genes in organogenesis and organ functionExtracellular matrix metabolism and disordersExtracellular matrix metabolism and cancer invasion-metastasis

KUNO Koji

Experimental pathologyStudy on the NLR family



Experimental pathology Study on Tumor Cell Invasion TAKINO Takahisa

Experimental pathology Inflammatory responses in gastrointestinal tumorigenesisGeneration of inflammation-associated gastric cancer mouse model OSHIMA Hiroko

Experimental pathologyCooperation of Wnt signaling and COX-2 pathway in gastrointeitinaltumorigenesisInflammatory host responses in gastrointestinal tumorigenesis

inflammation and cancer, genetics, mouse model OSHIMA Masanobu

Medical, D


Fundamental M

edicine


Experimental pathology Molecular Mechanisms regulatingTherapeutic-resistant CML stem cells

Therapeutic Resistance in Cancer Stem CellsMaintenance of Self-renewal Ability in Hematopoietic Stem Cells

Cancer stem cells, Cancer-microenvironment, Hematopoieticstem cells NAKA Kazuhito

Experimental pathology molecular mechanisms for self-renewal of stem cellsMaintenace mechanisms for genomic stability stem cell self-renewal hematopoietic stem cell HIRAO Atsushi

Parasitology (includessanitary zoology)

Development of drugs against novel anti-protozoan parasitesIntra-species diversity of intestinalprotozoan parasites

The challenges of chemotherapy against a pathogenic protozoon,CryptpsporidiumAnalysis of intra-species diversity in intestinal protozoan parasitesusing molecular taxonomyEpidemiologic analysis regarding parasitic burdens in endemic areas

Parasitology, Tropical medicine TOKORO Masaharu


Development of a novel malaria vaccine based on a non-infectious viralvectorElucidation of malaria parasite-mosquito salivary gland interactionusing transgenic mosquitoesElucidation of mechanism of malaria vaccine frailness caused byparasite-mediated immune disturbanceDevelopment of an anti-platelet drug targeted to collagen using a novelanti-platelet aggregation protein derived from mosquito saliva.

vaccine, malaria, anopheles, anti-platelet drug YOSHIDA Shigeto


Host Preference of mosquito vectorsChemical analysis of larval diet of African malaria vectors, Anophelesgambiae complexSiginificance of Mushroom Posion

Vector Ecology. Tropics. malaria. Japanese encephalitis. denguefever. biological control TUNO Nobuko

Bacteriology (includesmycology) Regulation of virulence and genome analysis of Clostridial species SHIMIZU Toru

Bacteriology (includesmycology) Development of treatment of bacterial

infectious disease

Cyclic ADP-ribose synthesis by bacteriaAnalysis of virulence factors of pathogenic clostridiaEcology of ┣DBClostridium botulinum(/)-┫DB

NAKAMURAShinichi

Bacteriology (includesmycology) Analysis of clostridium welchii toxin production adjustment mechanism OTANI Kaori

Virology Identification of novel molecular targetsthat interact with cancer genes

Identification of novel cancer genes using retroviral insertionalmutagenesis Tumor virus, Oncogene, Genome informatics SUZUKI Takeshi

Virology

recombinant vaccine

Molecular biology of negative strand RNA virusesInfluenza Virus VectorReverse genetic vaccine

Molecular biology of viruses ENAMI Masayoshi

Medical, D


Fundamental M

edicine


Virology

Molecular epidemiology of blood-borne viruses (HIV, HBV, HCV) inAsia and AfricaFactors influencing on disease progression of non-B subtype HIV-1-infected childrenGenetic analyses of drug resistance-associated mutations of non-Bsubtype HIV-1

Virology, International Health, HIV/AIDS ICHIMURA Hiroshi

Virology Drug Resistant HIV-1 infection in Vietnam Virology ISHIZAKI Azumi

Virology



Virology Epetain-Barr virus and nasopharyngeal carcinomaApplication of basic research for head and neck cancer chemotherapy MURONO Shigeyuki

Virology Molecular Biology of hepatitis B viruses Molecular Biology Virology KUROKI Kazuyuki

VirologyNasopharyngeal carcinoma associated with Epstein-Barr virusStudy of Sense of SmellSpeech pathological study

nasopharynx cancer metastasis Nose Olfaction FURUKAWA Mitsuru

Virology

Study of relation between viral genomic hypermutation andAID/APOBEC familyStudy of relation between HBV induced HCC and deaminasesRole of AID/APOBEC deaminase in HPV related oncogenesis.

Hypermutation, deaminase, hepatitis MURAMATSUMasamichi

Immunology Regulation of T cell activation T cell activation, Lymphocyte proliferation, Immune regulation INOBE Manabu

Immunology




Medical, D


Fundamental M

edicine


Immunology




ImmunologyPathology of the liverImmunology of the liverLiver cancer


Immunology



ImmunologyStudy on the NLR family



ImmunologyStudy on physiological role of Fas ligandStudy on Physiological Connection between Apoptosis andInflammation

IMAMURA Ryu

Immunology Mechanism of induction of central tolerance by thymic dendritic cells immunotolerance BABA Tomohisa

ImmunologyControl of inflammation and cytokineregulation

T cell differentiation in Immune Abnormality DisordersOxidative Stress and Immune ResponsePathogenic Mechanism of Abnormal Expansim of EBV-Infected Cells

Clinical Immunology YACHIE Akihiro

Immunology

Study of relation between viral genomic hypermutation andAID/APOBEC familyStudy of relation between HBV induced HCC and deaminasesRole of AID/APOBEC deaminase in HPV related oncogenesis.

Hypermutation, deaminase, hepatitis MURAMATSUMasamichi

Medical sociology Basic Research on Healthcare MarketingInternational HealthcareMarketingApplication of Artificial Intelligence to Healthcare

Healthcare Management, Hospital Administration, MedicalInformatics, Healthcare Legislation NAGASE Keisuke

Medical sociology



Medical sociology HO-1 in Caridiovascular homeostasisDiagnosis of congenital heart disease

Congenital heart diseases, Diagnosis Vascular Biology, Lifesupport PALS Prevention, Medical Education OTA Kunio

Medical, D


Fundamental M

edicine


Medical sociology



Medical sociology

Applying PDA(Personal Digital Assistant)inEvidence-Based MedicineApplying PDA(Personal Digital Assistant)inMedical Education

Profiling of the medical technologies required for general practiceHazards in applying evidence-based medicine to individual patientsClinical genetics in polycystic kidney disease and other geneticdiseases

General Internal Medicine Clinical Genetics NOMURA Hideki

Applied pharmacologyHuman UDP-GlucuronosyltransferaseGenetic polymorphisms of Drug-metabolizing enzymesRegulation of drug metabolizing enzymes

Drug metabolism, interindividual difference, geneticpolymorphisms NAKAJIMA Miki

Applied pharmacology

Genetic polymorphisms of Drug Metabolizing enzymesTranscriptional regulatron and induction mechanism of drugmetabolizing enzymesEvaluation and projection of toxicity and safety of drugs andenvironmental chemical substances

Drug metabolism, Molecular Pharmacology, Toxicology,Cytochrome P450 YOKOI Tsuyoshi

Pathologicalexamination studies





Disseminated intravascular coagulation,DICpathophysiology of thrombosis andhemostasis

Pathophysiology and treatment in disseminated intravascularcoagulationhttp://www.3nai.jp/weblog/index.htmlhttp://www.3nai.jp/weblog/index.html

ASAKURA Hidesaku


Therapeutic application of novel anti-inflammatory drugsDevelopment of novel laboratory medicineand biomarkers

Pathogenesis and Therapy in Diabetic NephropathyDevelopment of novel biomarkers in nephrology and autoimmunediseases.Molecular mechanism of kidney development and its application forregeneration

Nephrology Clinical immunology WADA Takashi

Pathologicalexamination studies the development of radiopharmaceuticals Radiopharmaceutical,Cancer,Bone OGAWA Kazuma

Pathologicalexamination studies Improvement of methods used in clinical laboratory HONMA Keiko

SocialM

edicine

Hygienics

Human health effects by chronic cadmiumexposureEstablishment of workers\' health caresystemHuman health effects by dioxin

Chronic Cadmium Intoxication Dioxin KIDO Teruhiko

Medical, D


Boundary Medicine


Hygienics Mechanism underlying dyskinesiaStudy on vegetables beneficial to health

Toxicology of environmental chemicalsBioactivity of nitriles from vegetables Environment, TANII Hideji

HygienicsHealth effect of KOSA bio-aerosolRelationship analysis of SNPs and cancerFunctional analysis of TGF-b binding protein

Cancer Molecular Biology Sing SNP HIGASHI Tomomi

HygienicsUnusual intracellular signal transduction induced by lipid peroxidationSearch for biomarker of oxidative stress in allergy diseasePrevention of health damage induced by earthquake

Oxidative Stress Preventive Medicine Allergic DiseaseEnvironmental Chemicals Evaluation of Toxicity

KANBAYASHIYasuhiro

Hygienics Analysis of genes and proteins which wereresponded to environmental change

Isolation of proteins which are responsible for brain functionStudies on molecular mechanisms of brain dysfunctionAlteration in signal transduction by aging and subsequentcarcinogenesis

Hygiene Neuro chemistry Molecular Biology SAIJO Kiyofumi

Public health/healthscience

Study of health education inservice trainingStudy of elementary school health textbooksrole-playing in school health education

Health Education IWATA Hideki


Mechanism underlying dyskinesiaStudy on vegetables beneficial to health

Toxicology of environmental chemicalsBioactivity of nitriles from vegetables Environment, TANII Hideji





Analysis of genes and proteins which wereresponded to environmental change

Isolation of proteins which are responsible for brain functionStudies on molecular mechanisms of brain dysfunctionAlteration in signal transduction by aging and subsequentcarcinogenesis

Hygiene Neuro chemistry Molecular Biology SAIJO Kiyofumi

Forensic medicine

Forensic Toxicological Screening in Emergency Medical Practice andForensic specimensForensic toxicology and molecular pathological analysis for MDMA.Analysis of deugs and poisons in the formalin-fixed organs.

Forensic toxicology, Forensic Toxicology for narcotics,Forensicserology,

TAKAYASUTatsunori

Forensic medicine



Forensic medicine Vascular Fragility, Forensic Pathology, Platelet ZUKA Masahiko

Medical, D


Social Medicine


SocialM

edicine

Forensic medicineResearch on Organ TransplantationResearch on Artificial ReproductionResearch on Gene Diagnosis

Student services in university educationThe artificial reproduction and gene diagnosisThe organ transplantation and self-determination

AONO Toru

General internalmedicine (includespsychosomaticmedicine)

Isolation and Structural Analysis of Biologically Active Natural ProductsStudy of natural products chemistry forinhibitors of metabolic enzymesSearch for functional substances using the antistress-scienceevaluation system

Natural Product Chemistry Pharmacognosy OTA Tomihisa


Clinical epidemiology for atherosclerosis

Study of Clinical Decision Making between Patients and Physicians onDiabetesClinical epidemiology of AtherosclersisDiabetology

Metabolism Cardiology Internal Medicine general medicinediabetes hyperlipidemia KOIZUMI Junji


Functional foodcancer chemopreventionComplementary and Alternative Medicine

Complementary and Alternative SUZUKI Nobutaka


IFN therapy for chronic hepatitis C chronic hepatitis hepatocellular carcinoma SAKAI Akito


Research for community medicine in Ishikawa PrefactureHemodialysis therapy for HCV infectionINF combined hepatic arterial chemotherapy for advanced HCC

Hepatocellular carcinoma Chenotherapy Percutaneous ablationtherapy

YAMASHITATatsuya


Coronary circulation physiology (explanation of mechanism ofmyocardial ischemia reflux disorder and its treatment, examination ofendothelin coronary circulation and its roles in ischemic condition)Myocardial regeneration after ischemia reperfusion injury

Ischemia reperfusion, Myocardial regenaration, Angiogenesis,Endotherin, Clinical electorophysiology

TAKAMURAMasayuki


Measurement of midkine in serum and pancreatic secretions, and itssignificance MORI Hisatsugu


Applying PDA(Personal Digital Assistant)inEvidence-Based MedicineApplying PDA(Personal Digital Assistant)inMedical Education

Profiling of the medical technologies required for general practiceHazards in applying evidence-based medicine to individual patientsClinical genetics in polycystic kidney disease and other geneticdiseases

General Internal Medicine Clinical Genetics NOMURA Hideki

Digestive organsinternal medicine IFN therapy for chronic hepatitis C chronic hepatitis hepatocellular carcinoma SAKAI Akito

Digestive organsinternal medicine Hepatitis B Virus, DNA/RNA editing enzyme KITAMURA Kouichi

Internal Clinical M

edicine

Medical, D



Digestive organsinternal medicine

KAWAGUCHIKazunori


Gene expression profiles in type 2 diabetes mellitusFatty liver-associated metabolic syndromePathophysiology of diabetic nephropathy

Diabetology Metabolism Endocrinology TAKAMURAToshinari


Research for community medicine in Ishikawa PrefactureHemodialysis therapy for HCV infectionINF combined hepatic arterial chemotherapy for advanced HCC

Hepatocellular carcinoma Chenotherapy Percutaneous ablationtherapy

YAMASHITATatsuya

Digestive organsinternal medicine MIZUKOSHI Eishiro

Digestive organsinternal medicine Methylation abnormality of cancer-related genes in pancreatic fluid Clinical OncologyGastroenterology OTSUBO Koshiro


Immune function in gastrointestinal diseaseGene therapy for cancerRegenerative Medicine

SAKAI Yoshio

Digestive organsinternal medicine KAGAYA Takashi

Digestive organsinternal medicine Study for genomics in liver

Cancer ResearchLiver metabolism and systemic illnessHepatitis Virus

Experimental Pathology, Virology, Cancer, Liver KANEKO Shuichi


Measurement of midkine in serum and pancreatic secretions, and itssignificance MORI Hisatsugu

Circulatory organsinternal medicine Clinical epidemiology for atherosclerosis



Circulatory organsinternal medicine

HO-1 in Caridiovascular homeostasisDiagnosis of congenital heart disease



Regeneration of Cardiovascular Cell and TissueSearch for novel gene mutation in development of cardiovasculardiseasesTherapeutic and control approach for atherosclerotic cardivasculardiseases

YAMAGISHIMasakazu

Medical, D


Internal Clinical M

edicine



Coronary circulation physiology (explanation of mechanism ofmyocardial ischemia reflux disorder and its treatment, examination ofendothelin coronary circulation and its roles in ischemic condition)Myocardial regeneration after ischemia reperfusion injury

Ischemia reperfusion, Myocardial regenaration, Angiogenesis,Endotherin, Clinical electorophysiology

TAKAMURAMasayuki

Circulatory organsinternal medicine Analysis of cardiomyopathy-related genes KONNO Tetsuo

Circulatory organsinternal medicine The role of MAFbx in cardiac remodeling Caldiology, heart failure, Cardiac remodeling USUI Soichiro


gene analysis of hypertrophic cardiomyopathyMechanism and therapy of arrhythmia arrhythmia. heart failure INO Hidekazu


The role of cardiovacular hormone in thepathogenesis of hypertension Study on Pathogenesis of Endocrine tumor Endocrinology Hypertension YONEDA Takashi

Circulatory organsinternal medicine Invention of Removal device for coronary stent Coronary artery intervention, coronary stent UCHIYAMA

Katsuharu


Regional differences of hypertensinogenicfactors in Hokuriku area.

Endocrinological study for the mechanism of hypertension anddiabetes mellitus Endocrinology, Hypertension, Diabetes mellitus TAKEDA Yoshiyu


Risk Factor of Atherosclerotic Cardiovascular DiseaseInhereted DyslipidemiaDiagnostic Imaging of Atherosclerosis

atherosclerosis,dyslipidemia KAWASHIRIMasaaki

Respiratory organinternal medicine

Basic and clinical research on Chemotherapy for Lung cancerMolecular targeted therapy for Lung Cancer Internal Medicine Respiratory System KASAHARA Kazuo

Respiratory organinternal medicine

Molecular targeted therapy for pleuralmesotheliomaReserach for investigating resistancemechanism to molecular targeted drugs inlung cancer

Elucidation of multiple-organ metastasis by lung cancerStudy of molecular mechanisms which induces resistance againstmolecular targeted drugsMolecular targeted therapy for malignant pleural mesothelioma

Cancer drug therapy, Lung cancer metastasis, molecular targetedtherapy, drug resistance YANO Seiji

Kidney internalmedicine




Kidney internalmedicine Mechanism of renal fibrosis Nephrology SAKAI Norihiko

Medical, D


Internal Clinical M

edicine


NeurologyDevelopment of diagnostic, therapeutic,and preventive methods for dementia andaging-related neurological disorders

Study on Brain Aging, Dementia, and AmyloidStudy on neuroinfection and neuroimmunologyClinical study on stroke and other neurological disorders

Neurology YAMADA Masahito

Neurology Comprehensive genetic analysis of congenital anomalies, geneticfixation with regard to autistic disorders congenital malformation syndro NIIDA Yo

Neurology Neuroimmunology neuroimmunology IWASA Kazuo

Neurology

Study of Immunotherapy for MyastheniaGravisStudy on autoantibodies from autoimmuneneurological diseasesNeuropsychological study related todevelopment and growth

Study of Immunotherapy for Myasthenia GravisImmunopathogenesis of autoimmune neurological disorderStudy of efficacy of health education in university setting

Neuroimmunology, Neuroscience, Neurology, Preventivemedicine

YOSHIKAWAHiroaki

Metabolism studies Clinical epidemiology for atherosclerosis



Metabolism studies Type 2 Diabetes, Insulin Resistance, Hepatokine, selenoproteinP, reactive oxygen species MISU Hirofumi

Metabolism studiesGene expression profiles in type 2 diabetes mellitusFatty liver-associated metabolic syndromePathophysiology of diabetic nephropathy


Metabolism studies The role of cardiovacular hormone in thepathogenesis of hypertension Study on Pathogenesis of Endocrine tumor Endocrinology Hypertension YONEDA Takashi

Metabolism studies Regional differences of hypertensinogenicfactors in Hokuriku area.


Metabolism studiesRisk Factor of Atherosclerotic Cardiovascular DiseaseInhereted DyslipidemiaDiagnostic Imaging of Atherosclerosis

atherosclerosis,dyslipidemia KAWASHIRIMasaaki

Endocrinology Clinical epidemiology for atherosclerosis



Medical, D


Internal Clinical M

edicine


EndocrinologyGene expression profiles in type 2 diabetes mellitusFatty liver-associated metabolic syndromePathophysiology of diabetic nephropathy


Endocrinology The role of cardiovacular hormone in thepathogenesis of hypertension Study on Pathogenesis of Endocrine tumor Endocrinology Hypertension YONEDA Takashi

Endocrinology Regional differences of hypertensinogenicfactors in Hokuriku area.


Hematology



ASAKURA Hidesaku

Hematology

Induction of graft-versus-leukemia effect after allogeneic stem celltransplantaImmunotherapy for hematologic malignanciesNovel treatment strategy for GVHD after allogeneic HSCT

HEMATOLOGY TAKAMI Akiyoshi

Hematology TAKAMATSUHiroyuki

Hematology



Hematology

Detecting target autigeus of the GVL effect after DLIAnalysis of immune reconstitution after allogeneic stem celltransplantationCancer immunotherapy targeting tumor-related antigens

GVL, mHA, TAAs KONDO Yukio

Hematology Physiology of heme oxygenase and itsdeficient state

Treatment of childhood cancer and acute leukemiaDrug resistanceHeme oxygenase-1 deficiency

Pediatric Hematology-Oncology Chemotherapy Drug resistance KOIZUMI Shoichi

Hematology molecular mechanisms for self-renewal of stem cellsMaintenace mechanisms for genomic stability stem cell self-renewal hematopoietic stem cell HIRAO Atsushi

Collagendisease/allergy/infectious disease medicine




Internal Clinical M

edicine

Medical, D




FUJII Hiroshi


infectious agent associated with rheumatoid arthritisImmunological analysis of Sjogren\'s syndromeIgG4-related disease and tuberculosis

rheumatoid arthritis, Sjogren syndrome, immunology, renaltransplantation, infection KAWANO Mitsuhiro

Pediatrics Comprehensive genetic analysis of congenital anomalies, geneticfixation with regard to autistic disorders congenital malformation syndro NIIDA Yo

Pediatrics HO-1 in Caridiovascular homeostasisDiagnosis of congenital heart disease


Pediatrics NAGAOKI Shuya

Pediatrics TOMA Tomoko

Pediatrics Physiology of heme oxygenase and itsdeficient state



PediatricsControl of inflammation and cytokineregulation

T cell differentiation in Immune Abnormality DisordersOxidative Stress and Immune ResponsePathogenic Mechanism of Abnormal Expansim of EBV-Infected Cells

Clinical Immunology YACHIE Akihiro

Embryonic/neonatalmedicine

HO-1 in Caridiovascular homeostasisDiagnosis of congenital heart disease


Embryonic/neonatalmedicine

Physiology of heme oxygenase and itsdeficient state



DermatologySclerodermaAntinuclear antibodyGrowth factor

TAKEHARAKazuhiko

Dermatology B cells, Autoimmunity FUJIMOTO Manabu

Internal Clinical M

edicine

Medical, D



Dermatology SclerodermaB cell Scleroderma, Anti-nuclear antibody, Fc receptor HAMAGUCHI

Yasuhito

Dermatology TAKASHI Matsushita

Dermatology Immunology about the pathogenesis of systemic sclerosisB cells and autoimmunity systemic sclerosis autoimmunity cytokine HASEGAWA Minoru

Psychoneurosis studies Schizophrenia, Cerebral Cortex, Pathophysiology HASHIMOTOTakanori

Psychoneurosis studiesMolecular mechanisms underlying addictionMolecular mechanismsunderlying major depressive disorderNeuronal plasticity in the nucleusaccumbens

TODA Shigenobu

Psychoneurosis studies study on neuropsychology andneurophysiology of schizophrenia

Study on neuropsychology and neurophysiology of schizophreniaCombined use of antipsychotics in the treatment of schizophreniapatients.

neuropsychiatry NAGASAWATatsuya

Psychoneurosis studiesNeurophysiological study on schizophreniaPathophysiology of anxiety disordersBrain developmental study using MEG/NIRS integrated device

Psychiatry, Neurophysiology KIKUCHI Mitsuru

Psychoneurosis studies Study on Child and Adulescent PsychiatryStudy on Child and Adolescent Psychopharmacology MUNESUE Toshio

Psychoneurosis studies MINABE Yoshio

Radiation science Clinical multicenter study on nulearcardiology

Nuclear Cardiology Cardiovascular ImagingLarge scale clinical trialatherosclerosis

Nuclear Cardiology, Cardiology,Imaging MATSUO Shinro

Radiation scienceDevelopment of ChAT mapping agent forAlzheimer\'s disease early diagnosis

Study on Syntheses of Radiopharmaceutical for cerebral nervefunction diagnosisDevelopment of a high sensitive evaluation of internal radiationexposure

Brain,moleculerimaging,radiation SHIBA Kazuhiro

Radiation science Radiotherapy KUMANO Tomoyasu

Internal Clinical M

edicine

Medical, D



Radiation science Radiology of the abdomeninterventional radiology KODA Wataru

Radiation science MINAMI Tetsuya

Radiation science Development of endovascular divices Diagnosis and treatment of hepatocellular carcinomainterventional angiography Radiology MATSUI Osamu

Radiation science Imaging Diagrosis of Abdomen Radiology GABATA Toshifumi

Radiation science Cancer radiotherapy Radio logy TAKANAKATsuyoshi

Radiation science MRS in rhe evaluation of brain tissue.

In vivo anatomical analysis of arterial contact with trigeminal nerve :Detection with 30-SPGR imagingDetermination of tissue Gd concentration by combined use of Pre-andpost Gd-enhanced FLAIR and cSE T1 weighted imagingDetection capability of the necessity for reembolization of three types ofMR angiography in the follow-up of intracranial aneurysms embolizedwith GDCS

Diagnostic Neuroradiology UEDA Fumiaki

Radiation scienceInterventional RadiologyEndovascular treatment of aortic aneurysm with stent-graftendovascular therapy for peripheral arterial disease

SANADA Junichiro

Radiation science the development of radiopharmaceuticals Radiopharmaceutical,Cancer,Bone OGAWA Kazuma

Radiation science Studies on developments of imaging andanalytical methods in MRI

Development of Pulse Sequences in Magnetic Resonance ImagingAssess of Magnetic Resonance(MR)Image QualityDevelopment of Functional Magnetic Resonance(MR) Imaging andAnalysis Methods

Magnetic resonance imaging Pulse sequence Medical imagingMagnetic resonance imaging Imaging method Medical imagingMagnetic resonance imaging Imaging method Pulse sequence

MIYACHI Toshiaki

SurgicalC

linicalM

edicine

General surgery

Development of effective educationalsystem in emergency and critical caremedicineEstablishement of effective emergencymedical service system

Pathophysiology of ischemia-reperfusion injury in the liverInduction of ischemic preconditioningAnalysis of factors related to survival in out-of-hospital cardiac arrests

Emergency Medicine Intensive Care Medicine Anesthesiology INABA Hideo

Internal Clinical M

edicine

Medical, D



General surgery

Basic research on low (ice)-temperature preservation of transplantinglungs with freeze-preservation polysaccharidesPerioperative identification method for lung cancer mediastinal lymphnode metastasis by tumor-specific antigens attached to a fluorescentcyclo-sphereRepair of intra-thoracic autonomic nerves using chitosan tubes

thoracic surgery, lung transplantation, less invasive surgery MATSUMOTO Isao

General surgeryCANCER METASTASIS, PERITONEALCARCINOMATOSIS

Involvement of chemokine ligand/receptor system in stomach cancerDevelopment of molecular target therapy targeted to CXCR4/CXCL12axis and HB-EGF in gastric cancer

SURGICAL ONCOLOGY, MOLECULAR BIOLOGY, GASTRICCACNER, PERITONEAL CARCINOMATOSIS YASUMOTO Kazuo

Digestive organ surgeryChemoprevention for Barrett\'s adenocarcinoma by cyclooxygenase 2inhibitorSentinel navigation surgery

Gastric cancer Peritoneal metastasis Hyperthermia FUJIMURA Takashi

Digestive organ surgeryMolecular Diagnosis of Colorectal CancerSerial Analysis of Gene Expression inStomach Cancer

Molecular oncology of gastrointestinal cancerSurgical oncology for gastrointestinal cancerEstablishment of tissue material resources of human gastrointestinalcancer

Gastrointestinal oncology, Surgical and molecular oncology MINAMOTOToshinari

Digestive organ surgeryCANCER METASTASIS, PERITONEALCARCINOMATOSIS

Involvement of chemokine ligand/receptor system in stomach cancerDevelopment of molecular target therapy targeted to CXCR4/CXCL12axis and HB-EGF in gastric cancer

SURGICAL ONCOLOGY, MOLECULAR BIOLOGY, GASTRICCACNER, PERITONEAL CARCINOMATOSIS YASUMOTO Kazuo

Digestive organ surgery Biological Behavior of Pancreatic Cancer Surgery for Pancreas and Biliary Tract OHTA Tetsuo

Digestive organ surgery

Intraoperative Manometric Examination in Treatment ofCholedocholithiasisSentinel Node Navigation Surgery for Gall Bladder CancerSelection of treatment method for common bile duct stones based onperioperative pressure in biliary tract

KITAGAWA Hirohisa

Digestive organ surgeryMultimodality therapy for peritoneal dissemination in gastric cancerMolcular biological investication of peritoneal metastases in gastriccancer

gastric cancer, peritoneal dissemination, multimodality therapy FUSHIDA Sachio

Thoracic surgery Study on Myocardial oxygen metabolism on beating heart surgeryusing near-infrared monitor Cardiovascular Surgery. TOMITA Shigeyuki

Thoracic surgery

Basic research on low (ice)-temperature preservation of transplantinglungs with freeze-preservation polysaccharidesPerioperative identification method for lung cancer mediastinal lymphnode metastasis by tumor-specific antigens attached to a fluorescentcyclo-sphereRepair of intra-thoracic autonomic nerves using chitosan tubes

thoracic surgery, lung transplantation, less invasive surgery MATSUMOTO Isao

Thoracic surgeryIntra-aneurysmal sac pressure change after stent-graftingStent-grafting for aortic arch aneurysmAssessment of therapeutic angiogentic therapy for lower limbs

Aortic aneurysm stent-graft Clinical angiogensis OTAKE Hiroshi

Medical, D


Surgical Clinical M

edicine


Thoracic surgery Basic and clinical research on awake off-pump coronary artery bypassgrafts Thoracic Surgery WATANABE Go

Cerebral neurosurgerySurgical treatment for cerebral strokeSurgical treatment for cerebral tumorSurgical treatment for head injury

MORI Masanao

Cerebral neurosurgery

Molecular targeted therapy for malignantgliomaThe molecular mechanism of gliomainvasionThe molecular analysis of malignant glioma

The analysis of invasion mechanism of malignant glioma and gliomastem cellTaylorMade molecular targeted therapy against malignant brain tumorThe exploration of biomarker for malignant glioma

glioblastoma, invasion, biomarker NAKADA Mitsutoshi

Cerebral neurosurgeryBrain TumorHydrocephalusPediatric Neurosurgery

KITA Daisuke

Cerebral neurosurgery

Promotion of「strategy for brain protection」Repetable battery for assessment ofneuropsychological status

Mechanism of adult neurogenesis and strategy for brain restorationIschemic neuronal death specific for the primate hippocampusAmnestic symptom due to hippocampal neuronal death

Neuroscience Regenerative Medicine Neurosurgery Neuroscience YAMASHIMATetsumori

Cerebral neurosurgery Studies on developments of imaging andanalytical methods in MRI

Development of Pulse Sequences in Magnetic Resonance ImagingAssess of Magnetic Resonance(MR)Image QualityDevelopment of Functional Magnetic Resonance(MR) Imaging andAnalysis Methods

Magnetic resonance imaging Pulse sequence Medical imagingMagnetic resonance imaging Imaging method Medical imagingMagnetic resonance imaging Imaging method Pulse sequence

MIYACHI Toshiaki

Orthopaedic surgerySpine Tumorbone tumorSpinal disease

Bone Tumor Spine Surgery Bone fracture TOMITA Katsuro

Orthopaedic surgery

Development of the treatment to promotebone formationDevelopment of immunotherapy for boneand soft-tissue tumorsDevelopment of new external fixators

Study on the treatment of musculoskeletal tumorsStudy on bone lengtheningThe role of fibrinolytic system in the formation of lung metastasis.Elucidation of the mechanism of lung metastasis and the developmentof the treatment strategy

Musculoskeletal tumor, Limb lengthening, Deformity correction,External fixation TSUCHIYA Hiroyuki

Orthopaedic surgeryPathogenesis of steroid-induced osteonecrosisBiomechanics of prosthetic jointsDeep venous thrombosis

Joint Disease KABATA Tamon

Orthopaedic surgery BONE TUMOR SOFT TISSUE TUMOR LIMB sarcomaChemotherapy limb salvage YAMAMOTO Norio

Medical, D


Surgical Clinical M

edicine


Surgical Clinical M

edicine

Orthopaedic surgery clinical approrch for dysphagiaselective control for rigospastic muscleexamination of muscle and joint flexibility

clinical evaluation and classification for physical deconditioningnew evaluation method of physical flexibilityclinical examination for swallowing disturbanceclinical assessment for physical deconditioning, therapeutic strategyfor physical deconditioningADL outcome after ruptured aneurysmal subarachnoid hemorrhagerecovery process of paraplegia after spinal cord decompressionswallowing disorder, assessment of dysphagia

musculoskeletal system, dysphagia, gait disturbance,rigospasticity, physical deconditioning, disuse syndrome, physicalfittness, rehabilitation

YAHATA Tetsutaro

Orthopaedic surgerySpine tumorsSpinal fusionOsteoporotic spine

spine tumor, osteoporotic spine, thoracic OPLL MURAKAMI Hideki

Anesthesiology/resuscitation studies

PharmacokineticsPrediction of difficult intubationPalliative Care

Anesthesiology YAMAMOTO Ken


Study on pharmacokinetics of intravenous anestheticsCardiac anesthesiaThe effects of anesthetics on evoked potentials

Anesthesiology Pharmacokinetics TSUBOKAWATsunehisa


Study on Stellate Ganglion BlockEffect of percutaneous vertebroplasty on metastatic centrum tumorsConsideration of oxycodone and fentanyl patches for cancer-relatedpain care

Anesthesiology pain management cancer pain YAMADA Keisuke

Anesthesiology/resuscitation studies KOMURO Akiko

Anesthesiology/resuscitation studies KURITA Akihide

Anesthesiology/resuscitation studies Sensitivity of Neuromuscular Blockers Anesthesiology ITO Hironori


Effect of Anesthetics in SepsisChange in Cytokines in Sepsis Sepsis, Cytokine, Blood Purification TANIGUCHI Takumi

UrologyProstatic CancerAndrogen receptorBone metastasis

Urology MIZOKAMI Atsushi

Medical, D



Urology KONAKA Hiroyuki

Urology spermatogenesis spermatogenesis MAEDA Yuji

Urology Urology MIWA Sotaro

Urology Genetic diagnosis on male infertility Study on spermagenetic geneSteroid metabolism on Prostate male infertility Y chromosome KO Eitetsu

Urologystudy on the molecular biology of male infertilityBasic and clinical study on hormonal therapy for prostate cancerStudy on crucial genes for spermatogenesis

male infertility, prostate cancer, spermatogenesis, men's health NAMIKI Mikio

Obstetrics andgynecology

Collection of stem cells in umbilical cordMatrix metalloproteinases in Obstetrics

Etiology and Treatment of Premature Rupture of Membranes (PROM)Management of medical and surgical complications in Pregnancy.Milk ejection reflex and Oxytocin.

PROM, Complicated Pregnancy, Milk ejection reflex UCHIDE Kiyoshi

Obstetrics andgynecology Gynecologic Oncology Telomerase Gene therapy NAKAMURA

Mitsuhiro


Analysis of telomernse activity in Gynecological tumorsAnalysis of transcriptional regulation of human papillomavirus geneexpressionAnalysis of transuiptional regnlation of P53 expression

KYO Satoru


Study on gynecological tumor and carcinogenesisStudy on human endometrial stem cell and carcinogenesisthe minimally invasive gynecological surgerymanagement of the mother in perinatal care

TANAKA Masaaki

Obstetrics andgynecology Transcriptional regulation of telomerase telomerase TAKAKURA

Masahiro


Development of hormone-drug releasesystem via supramolecular dissociation

DNA analysis in the study for carcinogenesis of Endometrial cancerand gene therapyHuman papilloma analysis in the carcinogenesis of uterine cervicalcancerGene therapy for ovarian Cancer

Molecular pathology in gynecologic field Auti-Cancenchemotherapy in Gynecologic field Cell aging and carcinogenesis INOUE Masaki

Obstetrics andgynecology Reproductive endocrinology on hypothalamo-pituitary axis Obstetrics and Gynecology KOIKE Koji

Medical, D


Surgical Clinical M

edicine


Otorhinolaryngology

Study on Central Auditory SystemEffects of oral administration of Japanese Herbal Medicine Juzen-taiho-to in otitis-prone childrenDrug-resistant Streptococcus pneumoniae in healthy children

Otolaryugology ITO Makoto

Otorhinolaryngology Head & Neck Cancer WAKISAKA Naohiro

Otorhinolaryngology Epetain-Barr virus and nasopharyngeal carcinomaApplication of basic research for head and neck cancer chemotherapy MURONO Shigeyuki

OtorhinolaryngologyNasopharyngeal carcinoma associated with Epstein-Barr virusStudy of Sense of SmellSpeech pathological study

nasopharynx cancer metastasis Nose Olfaction FURUKAWA Mitsuru

OtorhinolaryngologyStudy on Nasopharyngeal Carcinoma and Epstein-Barr VirusMechanism of metastasis in head and neck cancerExtracorporeal shock wave lithotripsy in salivary stones

Head and neck Tumor Epstein-Barr Virus YOSHIZAKITomokazu

Ophthalmology New drug for retinal neuoprotection IgG4-related disease in the orbital regionrituximab therapy in ocular lesion

TAKAHIRAMasayuki

Ophthalmology SNP analysis of drugs for the treatment of glaucoma SAKURAI Mayumi

OphthalmologyBasics and clinical practice of amnion transplantdevelopment of corneal endothelial keratoplastyin vivo confocal microscopic analysis of corneal disease

amniotic membrane transplantation, keratoplasty, endothelialkeratoplasty, in vivo confocal microscopy of cornea KOBAYASHI Akira

Ophthalmology Early detection of glaucomaGlaucoma examination model Glaucoma, Neuro-ophthalmology OKUBO Shinji

Ophthalmology YOKOGAWAHideaki

Ophthalmology Ocular toxicity of vitreous tamponade NISHIMURA Akira

Ophthalmology Molecular Biological Analyses on Diabetic RetinaMolecular Genetical Analyses on Eye Diseases HIGASHIDE Tomomi

Medical, D


Surgical Clinical M

edicine


Ophthalmology Pathogenic mechanism of glaucoma optic nerve damageOptic nerve regeneration and neuroprotection glaucoma SUGIYAMA

Kazuhisa

Emergency medicine

Frequency analysis of ventricular fibrillation in patients with out-of-hospital cardiac arrestHeart rate variability as a predictor of outcome for patients with braininjuryNew Methods for Cardiopulmonary Resucitation

Cardiovascular Surgery Emergency Medicine Emergrncymedicine Critical medicine GOTO Yoshikazu

Emergency medicine

Development of effective educationalsystem in emergency and critical caremedicineEstablishement of effective emergencymedical service system

Pathophysiology of ischemia-reperfusion injury in the liverInduction of ischemic preconditioningAnalysis of factors related to survival in out-of-hospital cardiac arrests

Emergency Medicine Intensive Care Medicine Anesthesiology INABA Hideo

Emergency medicine



ASAKURA Hidesaku

Emergency medicine TAKAMURA Hiroyuki

Emergency medicine OTA Keisuke

Emergency medicine Effect of Anesthetics in SepsisChange in Cytokines in Sepsis Sepsis, Cytokine, Blood Purification TANIGUCHI Takumi

Pathologicalodontology,odontological radiology

Etilology or treatment strategy ontemporomandibular disorders

Study on the Temporo mardibular Joint Disease, basically andclinicallyOral surgery

Oral Surgery TAKATSUKAShigeyuki

Preservativeodontological therapy

Study on the dental treatment with laser beamStudy on the layered manufacturing with metal powderStudy on the micro fabrication with laser beamStudy on Reduction of Residual Stress Induced during Rapid ToolingProcess

laser processing, SLS rapid prototyping, dental treatment FURUMOTOTatsuaki

Prosthetic odontologyTechnology with small fear ofcontamination in environmentStudies on laser processing

Studies on Temperature Measurement in MachiningCutting performance of spining toolStudies on Laser Processing

Workshop Processes and Production Engineering Metallurgy andMaterial Processing Prosthodontics and Dental Technology UEDA Takashi

Surgical odontology Etilology or treatment strategy ontemporomandibular disorders

Study on the Temporo mardibular Joint Disease, basically andclinicallyOral surgery

Oral Surgery TAKATSUKAShigeyuki

Medical, D


Surgical Clinical M

edicineO

dontology


Surgical odontology Invasion and metastasis of oral sguamous cell carcinoma Oral Surgery Oral Cancer KAWASHIRI Shuichi

Surgical odontology Evaluation of the relationship between occlusion andtemporomandibular joint in Jaw deformity patients

jaw deformity, temporomandibular joint disorder, boneregeneration UEKI Koichiro

Basic nursing science Prevention and Nursing Management for Pressure ulcersBasic research on pressure ischemic wounds support surface, animal model, wound care SUGAMA Junko

Community/elderlynursing science

Narrative approach to patients with depression have a history ofsuicide attemptSocial rehabilitation for people with schizophrenia

YASUDA Kyoko

Community/elderlynursing science Japanese-Brazilian NAGANUMA Rie

Community/elderlynursing science

Patterns of Difficulty Experienced by Nurses Caring for Elderly Patientswith Dementia in Medical Facilities TANIGUCHI Yoshimi

Medical, D


Odontology

Nursing Science

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