resume & research-ps
TRANSCRIPT
KeySkills
ProjectManagement
Research&Development
SOPDevelopment
RegulatoryCompliances
ChemicalSynthesis
ProductDevelopment&Analysis
ProcessEngineering
Consultancy
Reporting&Documentation
TeamManagement
ProfileSummary Ahighlyanalytical individualOfferingover7years’experienceinResearch&Development,andProcess/productImprovementinChemistry
Attained theHighest grade inPhD inFrance,Doctoratedegree, inChemistrywith“Trèshonorable”gradeinJuly2012
Leveraged with outstanding skills in conducting research on syntheticorganic& inorganicchemistryandsyntheticcoordinationpolymersbasedsustainablenewandadvancedmaterials
Widely experienced in milligram to kilogram scale multistep organicsynthesis, organometallic chemistry, heterocyclic chemistry, and air,moisture&lightsensitivereactionsandprocessdevelopment
Successfully published 9 journals of international repute including“TetraazaarenesbytheCeramidonineApproach”&"Structuralchemistryofbelt-shaped cyclonaphthylenes: Stereoisomerism, crystal structures anddynamics"whichwereselected&publishedonvariousplatforms
Gainedexpertiseinchemicalreactionandfamiliarinpreparationofvariousorganiccompoundsusingdifferentroutes
Expertise in ensuring compliance to quality and regulatory measures bymaintenanceofappropriatedocumentation/records
Capability to analyze & interpret unique problemswith a combination oftrainingexperienceandlogicalthinkingtofindtherightsolutions
Aleaderwithexcellentcommunication,analyticalandrelationshipbuildingskills
SoftSkills
CareerTimeline
Oct’12–Jan’13 Mar’13–Feb’14 Apr’14–Present
Education Ph.DinOrganicChemistryfromUniversityofBordeaux1,Francein2012
M.Sc.inChemistry(AnalyticalChemistryspecial)fromJadavpurUniversity,Indiain2009
B.Sc.inChemistryHonorsfromJadavpurUniversity,Indiain2007
Dr.ParantapSarkar,PhD
Goal-orientedprofessionaltargetingassignmentsinResearch&DevelopmentwithanorganizationofhighreputeinChemical/PharmaceuticalindustrypreferablyinMumbai,
Pune,Hyderabad,Chennai,Bengaluru,Kolkata,Delhi,Gujaratlocations
[email protected] +81-8016661857/+91-8001596340
IISER-Kolkata,Kolkata,IndiaasResearch
Associate
Communicator Innovator Thinker Collaborator Intuitive
EwhaWomansUniversity,Seoul,SouthKoreaasPost-DoctoralResearcheratChemistryandNanoSciencedepartment
WPI-AIMR,TohokuUniversity(AdvancedInstitutefor
MaterialsResearch),Sendai,JapanasResearchAssociate
NotableAccomplishmentsAcrossTheCareer CompletedDoctoratedegreeinChemistrywith“TrèsHonorable”gradeinJuly2012 Received EMMA (Erasmus Mundus External co-operational window with Asia,2009)scholarshipin2009
SelectedforNationalmeritscholarshipschemeby“MinistryofHumanResourceDevelopment,Govt.ofIndia”in2004
Supervisedinternprojectsof2undergraduateand3postgraduatestudents
WorkExperienceApr’14–PresentwithWPI-AIMR,TohokuUniversity(AdvancedInstituteforMaterialsResearch),Sendai,JapanasResearchAssociateMar’13–Feb’14withEwhaWomansUniversity,Seoul,SouthKoreaasPost-DoctoralResearcheratChemistryandNanoScienceDepartmentOct’12–Jan’13withIISER-Kolkata,Kolkata,IndiaasResearchAssociateRole:
Performingorganicandinorganicchemicalsynthesis(GNRs,Carbonaceousπe-richmacrocycles,Polymermaterials) Spearheading theR&DOperations&modificationof existingones,basedonmarket feedback& trends; supervisingdevelopmentofintermediatesandfinishedproductsasperpredefinedspecifications
Managing R&D analytical work & innovating various routes in synthetic organic chemistry (Functional aromatics &polyaromatics,Polymers,Pigments&Heteroaromatics,variouscrosscouplingmaterials,carbenes&radicalsetc.)
FacilitatingMethodDevelopment and validation i.e., rigorous testing of themethods to ensure that they are precise,accurate,reproducible,"fool-proof"andspecifictotheproduct&soon
Developingprocessesforformulationsbyestablishingprocessparameterstoachievequalityandyieldoftheproductasper requirement and predetermined specifications; conducting trials, identifying deviations & developing relevantmodificationstostabilizeproductsandscaleupprocesses.
Analyzing various processes/applications and recommending modifications & equipment calibrations to enhanceoperationalcompetence;performingliteraturesurveyusingScifinderandReaxysforchemicalsynthesis
Writing/reviewing detailed documents like process package, development report, validation reports & results;preparingofmonthlyreports,annualproductreports&periodicproductreview&soon
Publications P. Sarkar, I.-R. Jeon,F.Durola, andH.Bock, “Tetraazaarenesby theCeramidonineApproach”New J.Chem., 2012,36,570-574(IF:3.16&citation:6,selectedasCoverArticle)
P.Sarkar,P.Dechambenoit,F.Durola,andH.Bock,“Carboxy-functionalizedpolycyclicarenesbyoxidativecyclizationsof2,3-diarylacrylates”,AsianJOC,2012,1(4),366-376.(IF:3.3&citation:8)
P. Sarkar, F. Durola, and H. Bock, “Dipyreno- and diperyleno anthracenes from Glyoxylic Perkin reaction”, Chem.Commun.2013,49(68),7552-7554.(IF:6.8&citation:6)
H. Bock, D. Subervie, P. Mathey, A. Pradhan, P. Sarkar, P. Dechambenoit, E. Hillard, F. Durola, “Helicenes fromdiarylmaleimides”,Org.Lett.2014,16(6),1546-1549.(IF:6.3&citation:16)
E. Girotto, M. Ferreira, P. Sarkar, A. Bentaleb, E. A. Hillard, H. Gallardo, F. Durola, H. Bock, “Plank-Shaped Column-FormingMesogenswithSubstituentsonOneSideOnly”,Chem.Eur.J.2015,21(20),7603-7610.(IF:5.9,citation:1)
Z.Sun,P.Sarkar,T.Suenaga,S.Sato,H.Isobe,"Belt-shapedcyclonaphthylenes",Angew.Chem.2015,54,12800-12804.(IF:11.26,citation:11)
P. Sarkar, S. Sato, S.Kamata,T.Matsuno,H. Isobe, "Synthesis anddynamic structuresof ahybridnanohoopmoleculecomposedofanthanthrenyleneandphenylenepanels",Chem.Lett.2015,44,1582-1583(IF:1.23,citation:4)
Z. Sun, T. Suenaga, P. Sarkar, S. Sato, M. Kotani, H. Isobe, "Structural chemistry of belt-shaped cyclonaphthylenes:Stereoisomerism,crystalstructuresanddynamics",Proc.Natl.Acad.Sci.USA.2016,113,8109-8114.(IF:9.7,citation:1)
P. Sarkar, Z. Sun, T. Tokuhira, S. Sato,M. kotani,H. Isobe, "Stereoisomerism in nanohoopswith heterogeneous biaryllinkagesofE/Z-andR/S-geometries",ACSCent.Sci.DOI:10.1021/acscentsci.6b00240,Publishedonline,2016.
Conferences PosterNo.111(Ceramidonineapproachtohetero-nanoribbon),ISNA-14,Eugene,OR,USA,July,2011 Oralpresentationon“TowardsHeteroaromaticNanoribbons”atSECO-49,Annecy,France,May,2012 PosterNo.142(Carboxy-functionalizedpolycyclicarenesbyoxidativecyclisationsof2,3-diarylacrylates)atICPOC-21,Durham,UK,September2012
Poster No. 94 (Towards Electronically Tunable Graphene Nanoribbons From Glyoxylic Perkin Reaction)AIMS2015,Sendai,Japan,February,2015
Posterpresentation(Synthesisanddynamicstructuresofahybridnanohoopmoleculecomposedofanthanthrenylene
andphenylenepanels)AIMS2016,Sendai,Japan,February,2016 Oralpresentationon"Synthesisanddynamicstructuresofahybridnanohoopmoleculecomposedofanthanthrenyleneandphenylenepanels"atCSJAnnualmeeting2016,Kyoto,Japan,March2016
PosterNo.24(Synthesisanddynamicstructuresofhybridnanohoops),CURO-Pi-II,Eugene,OR,USA,September,2016
AcademicAchievements Ranked4th(71.33%)inPost-Graduation;1stinAnalyticalchemistryspecial,JadavpurUniversity,2009 Placed2ndinWestBengal(statelevel)inAchievement-cum-diagnosticTestinMathematics(ADTM)2001
Equipment’sExpertise ManagedequipmentsuchasNMRSpectroscopy(JEOLECS400&600,BrukerDPX300MHz),VT-NMR,UV-vis-NIR,CD-spectrometer, Polarimeter, DART & ESI-Mass spectroscopy, MALDI-TOF (HRMS), Cyclic Voltammetry, ATR/FT-IR,MultiplepreparativeHPLC,LC-MS,MPLC,GPC,GC,ColumnChromatography,XRD(beginnerlevel),DSC,TGA,UTM,DMA,Microscope, High-pressure reaction in Autoclave, Air-free technique (Glovebox, Schlenk line), Microwave reactor,Cryogenic reactor,Kugelrohr vacuumdistillation, SpinCoating, Electrochemical Polymerization,Dry solvent system/Solventrefinery,Karl-Fischertitrator,High-speedcooling¢rifuge
ITSkills OS:Windows,Mac Theoreticalcalculation:DFT,TD-DFT,PM6,Mechanics,Macromodel Chemdraw,ISICdraw,ACDLab3Dsimulation Sci-finder&Reaxys Origin8.5 DeltaNMR,Mestrec,iNMR Mercury&Chimera, MSOffice,C&Fortran
ExtracurricularActivities RegularmemberofChemistrydepartmentalcricketteamofJadavpurUniversity,2004-2009 RegularparticipantofScienceexhibitioninBirbhumZillaSchool,2000-2004 ElectedStudentrepresentativeforCampusrecruitment,JadavpurUniversityScienceFaculty,2008-2009
PersonalDetailsDateOfBirth:21stJuly1985LanguagesKnown:English,Bengali,Hindi,French,Japanese&KoreanAddress:SubhashPally,Suri,Birbhum,731101WB,India
Toknowaboutmyresearchworks,pleaseseebriefresearchoutlineinthenextpages.
BRIEFSYNOPSISOFRESEARCH
A.PhDResearch(2009-2012;UniversityofBordeaux1.CRPP-CNRS.Supervisor:Dr.HaraldBock):Project1:Thesynthesisofextendedheteroarenesviatheacidpromoteddehydrocyclisationofarylamino-anthraquinoneisexaminedasanapproachtohighlyconjugated-electronacceptormaterialsandeventuallytoheterographenenanoribbons.Whilst the latter perspective is found to remain challenging, the former is exemplified by the synthesis of extendedtetraazaheterocyclesbearingsolubilisingalkylsubstituents.
Project2:OxidativeDDQcyclizationinpresenceofMeSO3Hisexaminedasathree-stepapproachfromarylaceticacidsandaromaticaldehydestofunctionalizedcondensedarenes.Themethodis limitedtosystemsinwhichoneorbothofthetwoaryl moieties are more reactive than a phenyl group, such as 1-naphthyl or, especially, 3-thienyl. The extension of thisapproach to multiple cyclizations and, thus, to extended partially condensed systems with multiple alkoxycarbonylsubstituents appears promising with highly active precursors derived from 3-thienylacetic acid. A bifunctionalchrysenodithiophenewasobtained from1-5-diformylnaphthalene, togetherwithahighlyunusual asymmetricdimerwithcyclohepta[de]naphthalene(pleiadiene)moiety.
Project 3: Two fold Perkin condensation of arylglyoxylic acids and 2,5-dibromophenylene-1,4-diacetic acid followed bycyclo-dehydrobromination leads to extendedGNR fragmentswith tetra esters anddiimidesThe imides showsurprisinglylargeabsorptionshiftsversustheesters,illustratingthatelectron-withdrawingsubstituentsattheanthraceneunitefficientlyimpartlongwavelengthabsorptioninsuchelectrondeficientGNRfragments.
N
NN
N
O
O
Bu
Bu
N
OBu
NNN
OBu
N
N
N
NBu
Bu
2nd generation of azaarenes: Tetra-azaarenes
(New J. Chem., 2012, 36, pp. 570-574)
O
O
OHO
O
OTf
Bu
i) BuNH2 CoCl2
ii) Tf2O
N
Br
N
Bu
i) HNO3 / H2SO4
ii) Bu4Sn Pd(dppf)Cl2 N
NNH2
H2NN
N2 steps
O
O
OH
OH
O
O
OTf
OTf
Tf2O
NH2
( Asian JOC, 2012, 1 (4), pp. 366-376)
S
SCO2R
RO2C
SS
RO2C
RO2CS
S
CO2R
CO2R
S
S
CO2RRO2C
S
CO2R
S
CO2R
S
RO2C
S
3-step synthesis towards thiophene based hetero-polyaromatics
OH
O
OAc2O
NEt3
OHO
ORO
ORO
DDQMeSO3H
ROH
H+
Concept
Project4:Isomericdinaphthopyrene-tetracarboxydiimideshavebeensynthesizedfollowingsimilarrouteofProject3.Theseelongated GNR fragments self assemble into columnar liquid crystals of hexagonal and rectangular symmetry, of whichrectangular mesophases have unusually elongated unit cells. The cisoid diimides show a much greater tendency to self-assembleintofluidstacksofdisksthantheircentrosymmetricisomers
Project 5: [5]helicene and [7]helicene derivatives have been synthesized by two fold Perkin condensation followed byphotocyclodehydrogenation. The helicenes combine bathochromically shifted absorption and hypsochromically shiftedfluorescencewithrespecttotheirprecursors.
B.Post-doctoralResearch(2013-2014;EwhaWomansUniversity.Supervisor:Prof.JeanBouffard):Project6:SynthesisofstablecarbenesandN-heterocycliccarbenesandinvestigationoftheirreactivitytowardsC60andC70fullerenesinordertoachieveselectiveadductformationofdifferentfullereneswithdifferentcarbenes.
(Chem. Commun. 2013, 49 (68), pp. 7552-7554)
N
N
R R
RR
O O
O O
tetraester: 'Donor' type diimide: 'Acceptor' type
HO
O
O
COOH
HOOC
OH
O
O
COOH
HOOC
Br
Br
i) ClCOCO2Et ZrCl4
ii) NaHCO3
i) ClCOCO2Et ZrCl4
ii) NaHCO3
NBS
H2SO4
i) Ac2O / NEt3ii) ROH, H+
iii) Pd(OAc)2, PCy3 K2CO3, DMA
CO2RRO2C
RO2C CO2R
CO2RRO2C
RO2C CO2R
7-steps synthesis towards functional GNRs
N
N
R R
O O
RR
O O
R2NH
Imidazole
R2NH
Imidazole
i) Ac2O / NEt3ii) ROH, H+
iii) Pd(OAc)2, PCy3 K2CO3, DMA
RO2C
RO2C
CO2R
CO2RN
R
R
O
O
NR
R
O
O
CO2R
CO2R
CO2R
CO2R
NR
R
O
O
NR
R
O
O
tetraester: 'Donor' type diimide: 'Acceptor' type
(Chem. A. Eur. J. 2015, 21 (20), pp: 7603-7610)
tetraester: 'Donor' type diimide: 'Acceptor' type
N
Et Et
OO N
Et Et
OO
I2, O2
PhMe, reflux
( Org. Lett., 2014, 16 (6), pp. 1546-1549)
N
Et Et
OO N
Et Et
OO
I2, O2
PhMe, reflux
crystal structures
[5]helicne
[7]helicne
Project7:SynthesisandcharacterizationofstableN-heterocyclicbis-carbene.
C.Post-doctoralResearch(2014-Present;WPI-AIMR,TohokuUniversity.Supervisor:Prof.HiroyukiIsobe):Project 8:A hybrid nanohoopmolecule with 136 conjugatedπ-electrons composed of anthanthrenylene and phenylenepanelswassynthesized.StructuralanalysisbyNMRspectroscopyrevealedthesynchronousdynamicsofthearylenepanelsinthesolution,whichfurthersupportedbytheoreticalcalculations
Project9:i)Firstseriesofbeltshapedcyclonaphthyleneswithcurvedπ-systemhavebeensynthesizedandcharacterized.Themolecule[8]cyclo-amphi-naphthylene,islinkedatthe2,6-positionsofthenaphthyleneunits,thusaffordingbeltshapedmolecules.Althoughthemolecularstructuresareflexible,whichallowsfortherotationofthenaphthyleneunitsinsolution,theycanberigidifiedwiththeaidofmethylenebridgestoaffordpersistentmolecularstructuresinsolution.
ii)Seriesofbeltshapedcyclonaphthylenesconsistsofvariousnumbersofnaphthyleneunitshavebeensynthesized.Resultshowsthattherigidityofthenaphthyleneunitsinthemacrocycledependsontheringstrain.Rotationofnaphthyleneunitscompletelystopsinthesmallestmacrocycle[6]CaNAPatroomtemperature.
NN
NAr
ArAr
N
N
iPriPr
iPriPr
N
N
N
N
Ar
Ar
Ar
Ar
Carbene
(ongoing)
synthesis of stable carbenes and their adduct with C60 Fullerenes
NN
N
PhPh
Dipp
NN
N
PhPh
Ar
SSMeMe
2 OTf -3-steps
(writing in progress)
synthesis of bis-carbene
NNPh
Ph
O
O
Br
Br
Pigment Red 168
R
R
R
R
R
RR
R
R = -OC6H13
(Chem. Lett. 2015, 44, pp. 1581-1583)
2-stepsHighet benzannulated CPP ([16]CPP) with 136 π−electrons
R
R
Bpin
pinB
R
R
Bpin
pinB
2-steps 2-steps
(Angew. Chem. 2015, 54, pp. 12800-12804)
Br
Br
[8]cyclo-amphi-naphthylene (u-[8]CaNAP)
4-steps
1st Belt-shaped naphthylene macrocycle
!b-[8]CaNAP
u-[8]CaNAP
OO
Cu(OTf)2
DCE
pinB-Bpin [Ir(cod)OMe]2
dtbpy
pinB Bpin
i) PtCl2(cod), CsF THF, 70 °C
ii) PPh3, o-DCB 180 °C
Project10:ThisworkclarifiesuniquecyclostereoisomerismofacyclophenanthrenylenenanohooppossessingbothE/ZandR/S-geometriesatthebiaryllinkages.The7stepssynthesisof[8]CPhen3,9givestwomoststableenantiomersinitscrystalstructureoutofpossible51stereoisomers.Experimentalinvestigationsofthedynamicbehaviorsofthenanohooprevealedthe presence of two-stage isomerization processes taking place separately at the E/Z- and R/S-linkages. Consequently,despitethepresenceofE/Z-fluctuations,theR/Saxialchiralityresultedinaseparablepairsofenantiomers.
(ACSCent.Sci.,2016,DOI:10.1021/acscentsci.6b00240,Publishedonline)
BrBr
BrBr
n
n= 1,2,3
pinBBpin
n
n= 1,2,3
BO
OBpin =
n
n= 6,7,8,9,10,11
i) t-BuLi
ii) CuCN
pinB-Bpin
PdCl2(dppf)•CH2Cl2 KOAc, dioxane
i) PtCl2(cod), CsF THF, 70 °C
ii) PPh3, o-DCB 180 °C
( PNAS, 2016, published online)
HO2C
Me
Br HO2C
Me
Br
I2hν
cyclohexanert, 48 h
I
Me
Br
hν
Cl2CHCHCl2reflux, 15 h
NN
O
OI I
Me
Br
Me
Br
PtCl2(cod), CsFTHF70 °C, 24 h
PPh3, o-DCB180 °C, 48 h
1.
2.
pinB-BpinPdCl2(dppf)•CH2Cl2
KOAc
dioxane80 °C, 18 h
Me
Bpin
Me
pinB
BuLi; CuBr2; PhNO2
THF
8
Me
ESESESESERERERER
MP
HO2C
Me
BrOHC
Ac2O, Et3N
THF, 12 h, reflux
300 350 400 450 500 550
CD
/ mde
g
–80
–40
80
40
0
wavelength (nm)
ERERERER
ESESESES