RetinoblastomaRetinoblastoma

By By

Toni DempseyToni Dempsey

Ben LandryBen Landry

Natalie ParsleyNatalie Parsley

Guy StatonGuy Staton

Tiffany WilcoxTiffany Wilcox

Ashley WillmannAshley Willmann

What is What is Retinoblastoma?Retinoblastoma? Childhood cancerChildhood cancer Caused by immature retinal cells in Caused by immature retinal cells in

one or both eyesone or both eyes It is most common eye cancer in It is most common eye cancer in

childrenchildren 350 new cases in US each350 new cases in US each

year and over 5000 cases year and over 5000 cases

worldwideworldwide

Common SignsCommon Signs

A white “glow” in the pupil of the A white “glow” in the pupil of the eye in dim lightingeye in dim lighting

Crossed or misaligned eyesCrossed or misaligned eyes Poor visionPoor vision Swollen tissue around the eyeSwollen tissue around the eye

DiagnosisDiagnosis

Fundoscopic examination Fundoscopic examination Computed tomography scanComputed tomography scan MRIMRI Blood testsBlood tests Genetic and/or DNA testingGenetic and/or DNA testing

TreatmentTreatment

Individualized for each patient – Individualized for each patient – patients survival is primary goalpatients survival is primary goal

EnucleationEnucleation External Beam RadiationExternal Beam Radiation Radioactive PlaquesRadioactive Plaques

Treatment (cont.)Treatment (cont.)

Laser TherapyLaser Therapy CryotherapyCryotherapy Chemoreduction/ChemotherapyChemoreduction/Chemotherapy New Clinical Trial TreatmentsNew Clinical Trial Treatments

Case StudyCase Study

Child diagnosed at 2 years of age Child diagnosed at 2 years of age with Bilateral Retinoblastomawith Bilateral Retinoblastoma

Treated with Chemotherapy and Treated with Chemotherapy and Radiation Radiation

Both eyes eventually had to be Both eyes eventually had to be enucleatedenucleated

He developed unique adaptationsHe developed unique adaptations

ImplicationsImplications

Early diagnosis is criticalEarly diagnosis is critical If left untreated cancer can If left untreated cancer can

spread spread

Over 95% of children in US Over 95% of children in US survive and lead normal livessurvive and lead normal lives

Follow up appointments are Follow up appointments are important to detect possible important to detect possible secondary cancerssecondary cancers