reversing the invisible epidemic of autoimmune disease
TRANSCRIPT
©2016-Allrightsreserved.
ReversingtheInvisibleEpidemicofAutoimmuneDisease
DIYComestoAutoimmunity
YourAutoimmunityConnection
+1.310.666.5312 [email protected] www.drbonnie360.com @DrBonnie360
©2016-Allrightsreserved.
MyRole:A=ackingtheAutoimmuneEpidemicAhuge,growinganduntappedmarketopportunity>CVD+CancerObscuredbystaLsLcalgaps,scaMeredacrossmulLplebodypartsandspecialLesAbig,expensive,underappreciatedpartofthechronicdiseaseepidemicThe@meisnowtotacklethisinvisibleepidemic!
DrBonnie360’sServices• Convergingscience,technology,paLentdemand
• NewR&D:-omics,immunology,systemsbiology,root-cause• ITinfrastructure:ubiquitoussmartmobile,API/Cloud,WWW• EmergingautoimmunecommuniLes,demand(e.g.diet)
• Emergingtechnologypla_orms• PointsoluLonsindiabetesandobesityshowhowlifestyle
modificaLonscanimprovequalityoflifeandsavemoney.• Newpla_orms,portals,communiLesarebeginningtoscale
health,wellnessandprevenLon.• Advancesintechnologyprovidetoolstoimprovecaredelivery
CorporateStrategy
BusinessDevelopment
CommunityDevelopment
CommunicaLons&Design
MarkeLng&Sales
©2016-Allrightsreserved.
Huge&GrowingUnmetNeed
50Million(16%)AmericanswithAutoimmuneDiseases
• 1in6Americans• PopulaLonof25states• >CVD+Cancer
100+autoimmunediseases
ATop10causeofdeathinwomen<64yo
IBDincidenceDoubledchildren<10yo(1991-2002)
©2016-Allrightsreserved.
Under-Recognized&Under-Researched:
16%
10%
6%
68%
USPa@entPopula@on
6%
24%
37%
33%
2014NIHGrantAlloca@ons
AutoimmuneDiseaseCardiovascularDiseaseCancerOther
©2016-Allrightsreserved.
UntappedMarketOpportuni@es
By2023,
230MillionAmericanswithchronicdiseases,cosLng$4.2Trilliontotaltreatmentpluseconomicoutput
$8/10spentonhealthcare
goestochronicdiseases
27%children<19haveatleastonechroniccondiLon
7/10DeathsAnnuallyduetochronicdiseases
129%Increaseforspecialty
autoimmunemedicinefrom2011-2015($20.9B–$47.9B)
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OpportunityforIndividualizedAutoimmuneMedicineNOWTop-DownConvergence
Advancesintechnologyandscienceprovidetoolsfordigitalindividualizedmedicine:
2016
2015
2014• Apple,Amazon,Googleenter
healthcaremarket• #ofpersonalgenomicscompaniesdoubled
• ClevelandClinicopensafuncLonalmedicinecenter
• MicrobiometherapeuLcs• Immuno-oncology• Telemedicine&telehealth• VirtualeducaLon&digitalcoaching
• IBMWatson,AppleHealthkit
• AcLveM&ApointsoluLonstopla_orms
• ClevelandClinicbeginsoutcomes/costclinicaltrials
• WellnessasaService
©2016-Allrightsreserved.
NeedIndividualizedAutoimmuneMedicineNOWBoMom-UpConvergence
AutoimmunepaLentsdesperatelyseekingearlierdiagnosesandsustainabletreatmentsthataddressrootcauses• Gapsindiagnosis&treatment• Average:3.5years&5doctorstoDx• 51%labeledchroniccomplainers• MoreautoimmunethancancerpaLentswithpoorqualityoflife• RheumatoidarthriLs87%vs.
Breastcancer39%
Needs Trends• Crowdsourcing,CiLzenScienceandmakermovement
• Onlinecommunitysupportgroups&growingpaLentpower
• QuanLfiedSelf,N=1ClinicalTrials,experimentswithdiet&supplements
• EmergenceofFuncLonalMedicineprogramsinconvenLonalserngs
©2016-Allrightsreserved.
- Rem
ote
Mon
itorin
g - Chronic Disease Marketplace/Platform - Functional and Conventional Coordination
- Personalization
- Individualized
- Data Collection
REGENERATION
BridgingtheGap–IndividualizedAutoimmuneCare
©2016-Allrightsreserved.
ContactUs
+1.310.666.5312
www.drbonnie360.com
@DrBonnie360
www.facebook.com/YourAutoimmunityConnecLon
BonnieFeldman,DDS,MBADrBonnie360’smissionistocreateadigitallyconnectedworldofpersonalizedcareforautoimmunepaLents.Weconsultwithstart-upcompaniesandentrepreneurswhoarebringingnewproductsandservicesthatwillimproveresearch,diagnosis,andtreatmentforautoimmunity
©2016-Allrightsreserved.
Sources• Huge&GrowingUnmetNeed
• 50MillionAmericans&100+AutoimmuneDisease–“WhyisAuotoimmuneDiseaeUnderserved,”DrBonnie360,Mar2015.hMp://bit.ly/1B57pNb
• Top10causeofdeath–AARDAAutoimmuneDiseaseFactSheet.hMp://www.aarda.org/autoimmune-informaLon/autoimmune-staLsLcs/
• IncreasingIncidenceinIBD–“RisingIncidenceofInflammatoryBowelDiseaseamongChildren:a12-yearStudy,”JournalofPediatricGastroenterology&NutriLon,Jan2010.hMp://bit.ly/1Zeg3b6
• Under-recognized&Under-Researched• 16%oftheUSPopulaLonisAutoimmune–AARDAAutoimmuneDiseaseFactSheet.hMp://www.aarda.org/autoimmune-
informaLon/autoimmune-staLsLcs/• <6%ofNIHFundinggoestoautoimmunity–“Health,UnitedStates,2013withSpecialFeatureonPrescripLonDrugs,”Center
forDiseaseControlandPrevenLon,2014.hMp://www.cdc.gov/nchs/data/hus/hus13.pdf#042
• UntappedMarketOpportunity• 27%ofChildren–“ChronicCare:MakingtheCaseforOngoingCare,”RobertWoodJohnsonFoundaLon,Mar2010.• 7/10Deaths–“ChronicDiseasePrevenLonandHealthPromoLon,”CenterforDiseaseControlandPrevenLon,Aug2016.• 129%Increase–“MedicinesUseandSpendingintheU.S:AReviewof2015andOutlookto2020,”IMSInsLtuteforHealthcare
InformaLcs,Apr2016.• $8/10Dollars–“TheDigitalRevoluLoncomestoUSHealthcare,”GoldmanSachs,Jun2015.• 230MAmericanscosLng$4.2T–“CheckupTime:ChronicDiseaseandWellnessinAmerica,”MilkenInsLtute,Jan2014.