by

International Trade and MarketingCEO Dr. Amr M. Helal

Rice Residues Management

Innovative Industrial Investment

Approach with Scientific Evidence and Support

Innovative Products

from Waste material to Healthy aging products

Where we are

Where we plan to go

Dream or Reality

Before we startsNumbers Never Lies

List of exporters for the selected product in 2013 Product : 1211 Medicinal plants

Value exported in 2013 (USD thousand)

Trade balance in 2013 (USD thousand)

World 3,399,350

China 1,196,725

India 207,758

Canada 184,930

United States of America

168,286

Germany 148,372

Egypt 109,845

Korea, Republic of 109,379

List of exporters for the selected product in 2013 Product : 30 Pharmaceutical products

Trade Indicators 

Value exported in 2013 (USD thousand)

Trade balance in 2013 (USD thousand)

World 486,308,192

Germany 73,779,288

   

Israel 6,099,722

Best Investment !

On going Success StoryAll started through IMC initial support

Egyptian Side

- German University in Cairo- Faculty of Pharmacy Cairo U.- National Research center- Faculty of Agriculture, Man. U.- Health Tech - Al Sonbolah Rice Mill- International Trade and marketing

German Side

-Faculty of Pharmacy Goethe University-Faculty of Pharmacy Muenster University-VIVA cell Biotechnology-Fb- Food Germany-Analyze and realize (a&r)(Baspharma Holland)

Rice Bran

in Egypt Total Rice cultivated area

>1.5 Million Acers > 500,000 MT Rice bran

Rice Milling Processes

Husk removed Bran removed

milling process converts brown rice white rice i.e removes Bran

destroys 67% of the vitamin B3, 80% of the vitamin B1, 90% of the vitamin B6, 50% of the manganese, 50% of the phosphorus, 60% of the iron, and

almost 100% of the dietary fiber essential fatty acids antioxidants Oryzanol, Vitamin E

“Tocopherols & Tocotrienols”* i.e white rice is required to be "enriched" with at least

vitamins B1, B3 and iron

Brown rice ≠ White rice

is one of the most nutritive ingredients of the rice crop, where about 60% of the total nutritive value of rice itself resides

Rice Bran

PROTEIN

OIL DIETARY FIBRE VITAMINS & MINERALS

GAMMA ORYZANOL

ANTIOXIDANTS TRACE

ELEMENTS

RICE BRAN

These components can be obtained from other sources in nature separately, but Rice Bran is unique in having them all

Rice Bran vs. Wheat Branhttp://www.healthaliciousness.com/nutritionfacts/nutrition-comparison.php?o=20034&t=20060&h=20077&s= 219.00&e=118.00&r=58.00

Nutrition FactsRice bran crude

Serving Size 118gCalories 373

% Daily Value*

Total Fat 24.6g 38% Saturated Fat

4.922g 25%

Cholesterol 0mag 0%Sodium 6mg 0%

Total Carbohydrate 58.6g 20%

Dietary Fiber 24.8g 99%

Sugar 1.1g ~Protein 15.8g ~

Nutrition FactsWheat bran crude

Serving Size 58gCalories 125

% Daily Value*

Total Fat 2.47g 4%

Saturated Fat 0.365g 2%

Cholesterol 0mg 0%

Sodium 1mg 0%

Total Carbohydrate 37.4g 12%

Dietary Fiber 24.8g 99%

Sugar 0.2g ~

Protein 9g

Rice Bran vs. Wheat BranMinerals %DV

Calcium 67.26mg 7%Iron 21.88mg 122%

Magnesium 921.58mg 230%Phosphorus 1978.86mg 198%

Sodium 6mg 0%Potassium 1752.3mg 50%

Zinc 7.13mg 48%Copper 0.859mg 43%

Manganese 16.768mg 838%Selenium 18.41μg 26%

Water 7.23g ~Ash 11.78g ~

Vitamin E “25.6-30.0 mg%” **alpha-Tocopherol 4.92 mg 25%

Tocotrienols 73.5%Phytosterols 450 mg%

Minerals %DVCalcium 42.34mg 4%

Iron 6.13mg 34%Magnesium 354.38mg 89%Phosphorus 587.54mg 59%

Sodium 1mg 0%Potassium 685.56mg 20%

Zinc 4.22mg 28%Copper 0.579mg 29%

Manganese 6.67mg 334%Selenium 45.01μg 64%

Water 5.74g ~Ash 3.36g ~

Vitamin E “3.5-4.6 mg%” **alpha-Tocopherol 1.09 mg 7%

Tocotrienols 65-71%Phytosterols 147-195 mg%

Rice Bran Fatty AcidsOmega 3 to Omega 6 Ratio 0.04Omega 6 to Omega 3 Ratio 22.6

Total Omega 3s 373mg18D3 Linolenic 373mg

Total Omega 6s 8429mg18D2 8429mg

Wheat Bran Fatty AcidsOmega 3 to Omega 6 Ratio 0.08Omega 6 to Omega 3 Ratio 12.21

Total Omega 3s 97mg18D3 Linolenic 97mgTotal Omega 6s 1183mg

18D2 1183mg

RB- Essential Amino Acids %RDITryptophan 127mg 45%Threonine 655mg 62%Isoleucine 670mg 48%Leucine 1206mg 44%

Lysine 767mg 37%Methionine 361mg 50%

Cystine 374mg 130%Phenylalanine 749mg 86%

Tyrosine 485mg 55%Valine 1040mg 57%

Essential Amino Acids %RDITryptophan 164mg 59%Threonine 290mg 28%Isoleucine 282mg 20%

Leucine 538mg 20%Lysine 348mg 17%

Methionine 136mg 19%Cystine 215mg 75%

Phenylalanine 345mg 39%Tyrosine 253mg 29%

Valine 421mg 23%

Rice Bran Nutraceutical / Functional Food Values

Potent Antioxidant

High Nutritional Value

Blood Pressure

Blood Cholesterol

Potential benefits of RICE BRAN

Blood Sugar

However due to non stabilization of Rice Bran; it is still discarded or used as animal feed despite its high content of bioactive substances.It all starts with IMC support for :

RICE BRAN INNOVATIVE STABILIZATION

Project Name Funding Authority Budget Rice Bran Stabilization Unit (5-7-1) Faculty of Agriculture, Mansoura University2007-2008

Industrial Modernization Centre (IMC)

70,000 L.E.

Rice Bran Stabilization Industrial Unit (1-12-53) Faculty of Agriculture, Mansoura University2009-2010

Industrial Modernization Centre (IMC)

700,000 L.E.

Rice Bran Phytochemical Study (3-7-4)National Research Centre 2008-2009

Industrial Modernization Centre (IMC)

100,000 L.E.

Rice Bran Industry Implementation (5-7-2)National Research Centre 2008-2010

Industrial Modernization Centre (IMC)

200,000 L.E.

Project Name Funding Authority Budget

Developing Rice Bran Nutraceuticals (MED/2008/214-423) • Faculty of Pharmacy Cairo

University, Egypt • Faculty of Pharmacy Goethe

University• VivaCell Biotechnology GmbH,

Germany • Faculty of Pharmacy, GUC, Egypt 2009-2011

Research Development & Innovation Programme (RDI)

EURO 192,500

Project Name Funding Authority Budget

Ultrasonic Extraction with Spray Drying of Rice Bran Extract (RDI2/S2/26) • Faculty of Pharmacy Cairo

University • Analyze & Realize, Germany • BasPharma, The Netherlands

2014-2015

Research Development & Innovation Programme (RDI)

EURO 104,000

Current Projects

Business Scope; R&D

Research Partners:1. Faculty of Pharmacy, Cairo University, Egypt 2. Faculty of Pharmacy, GUC3. National Research Centre, Egypt4. Faculty of Pharmacy, Goethe University, Frankfurt, Germany 5. Wageningen University (Algae Park), Holland6. Ainia Centro Tecnologica, Spain 7. BasPharma, The Netherlands8. VivaCell Biotechnology GmbH, Germany9. International Trade and Marketing (IT&M)*

(Projects coordinator and HT founder)

Rice Bran Stabilization (Lab &Industrial Scale)

• Applicant: Faculty of Agriculture ., Mansoura Univ.

• Duration : 9 and 12 months respectively

• Budget : LE 70 000 and 700 000 respectively

• Project PI : Prof. Dr. Ahmed Mohmoud Matouk

• Industrial Beneficiary: International trade and Marketing

• The main objective of the project is to develop Different and Novel Rice Bran Stabilizers both on the lab scale in the first project and at the industrial scale in the second project.

• Pilot units will be fabricated to suit different rice varieties and different mills designs. The whole stabilization factors; temperature, time, feeding rate...Etc will be recorded and controlled from a remote station.

Rice Bran – Stabilization Unit 1Capable of stabilizing the bran of 150 MT rice milling / day

Phytochemical &

Nutritional study of the Stabilized Rice Bran.

• Applicant : National research Centre

• Budget : LE 200 000 Duration : 24 months

• Project PI : Prof. Dr. Sahar Youssef Al-Okbi

• Industrial Beneficiary : International Trade and

Marketing

• The phytochemical constituents of rice bran are explored.

• Assessment of proximate composition of de-oiled rice bran (meal) including proteins, residual fat, carbohydrate, ash, moisture, crude fibres and calories will be carried out.

• Amino acid profile, minerals, dietary fibres (soluble & insoluble), total phenolic and flavonoids were determined in the meal.

• Shelf stability of the different extracts were assessed. The best extraction technique will be established on industrial scale. Estimation of the cost on both the laboratory and industrial scale will be carried out.

Implementations of Stabilized Rice Bran

in Different Fields

• Applicant: National research Centre

• Budget : LE 100 000 Duration : 12 months

• Project PI : Prof. Dr. Sahar Youssef Al-Okbi

• Industrial Benificary : International trade and

Marketing

• Preparation of different stabilized rice bran products (rice bran, rice bran oil, extracts and de-oiled rice bran).

• Preparation of food, cosmetic and pharma-ceutical products fortified with rice bran products.

• Physical and sensory evaluation with flavor determination.

• Proximate analysis of food products. • Design of nutritional information in relation to daily

requirements that may be written on labels (of food products).

Publications• Sahar Y. Al-Okbi, Ahmed M.S. Hussein, Ibrahim M. Hamed, - Doha A. Mohamed and

Amr M. Helal, Chemical, Rheological, Sensorial and Functional Properties of Gelatinized Corn- Rice Bran Flour Composite Corn Flakes and Tortilla Chips, Journal of Food Processing and Preservation, 2012 (Wiley) , doi:10.1111/j.1745-4549.2012.00747.x

• Hussein O Ammar, Sahar Y Al-Okbi, Dina M Mostafa and Amr M. Helal, Rice bran oil: Preparation and evaluation of novel liquisolid and semisolid formulations. International Journal of Pharmaceutical compounding, 16 (6), 2012, 516-523 (USA).

• Sahar Y. Al-Okbi, Doha A. Mohamed, Ibrahim M. Hamed, Fatma S. Agoor, Asmaa AM. Ramadan, Shimaa El-Saed, Amr M. Helal, Comparative Study on Egyptian Rice Bran Extracted by Solvents and Supercritical CO2. Advances in Food Sciences, 35 (1), 2013, 23-29. (Germany).

• Sahar Y. Al-Okbi, Nagwa M. Ammar, Doha A. Mohamed, Ibrahim M. Hamed, Ahmad, H.

Desoky, Hagar F. El-Bakry, and Amr M. Helal. Egyptian rice bran oil: chemical analysis of the main phytochemicals. Accepted in La Rivista Italiana delle Sostanze Grasse in 25 January, 2013 (Italy).

Publications (cont.)• Rice bran solid lipid nanoparticles: Preparation and characterization

Mohamed Hassan Hany and Omaima Naim El Gazayerly International Journal of Research in Drug Delivery 2011; x (y): zz-zz ( http://www.urpjournals.com ). (Through rice bran nutraceutical project)

• Antidiabetic effects of a standerdized Egyptian Rice Bran; Rebecca M.

Kaup; Mohamed T. Khayyal; Eugen J. Verspohl. Phytotherapy Research Volume27, Issue2, pages 264-271 (2013) (Through Dr. Helal project)

• • 59th International congress and annual meeting of the society for

medical plants and Natural Product Research (4th-9th September2011, Antalya, Turkey).

Publications (cont.)

• Rice bran extract protects from mitochondrial dysfunction in guinea pig brains.

Hagl S1, Kocher A, Schiborr C, Eckert SH, Ciobanu I, Birringer M, El-Askary H, Helal A, Khayyal MT, Frank J, Muller WE, Eckert GP.Pharmacol Res. 2013 Oct;76:17-27. doi: 10.1016/j.phrs.2013.06.008. Epub 2013 Jul 1.• Rice bran extract compensates mitochondrial dysfunction

in a cellular model of early Alzheimer's disease.Hagl S1, Grewal R1, Ciobanu I1, Helal A2, Khayyal MT3, Muller WE1, Eckert GP1.J Alzheimers Dis. 2015;43(3):927-38. doi: 10.3233/JAD-132084.

PorridgePlus - a food against dementia

Aim to develop a food product for elderly with the objective to promote healthy brain aging

Products under registration

Stabilized Rice Bran Sachets

Products under registration (Cont.)

RICPLEX

20 Soft Gel capsules

Nutraceutical Products; Rice Bran Planned products

Rice Bran Spray Dried Powder (Healthy Creamer)

Rice Bran / Ginkgo product range (Capsules – Soluble Powder)

Rice Bran/ Barley product range (Capsules – Soluble Powder)

INNOVATION AWARDS

Contact Data

• Address: 118 Mohy El Dein Abo El Ezz. Giza POC 12411- EGYPT

• Tel: 00202 33045736• Fax: 00202 33477755• Email: dr.amrhelal@healhtech-eg.com• Web site : www.healthtech-eg.com

Nations’ s Wealth

Is not by what they have

Or what they know

But

By Knowing what to do

with what they have

Thank you!

Healthtech-eg.com