risk factors for dementia - the lancetthelancet.com/.../risk_factors_for_dementia.pdf5% b i r t h...

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5% B i r t h Hearing loss Hypertension Obesity Smoking Depression Physical inactivity Low social contact Diabetes 8% 9% 5% 4% 3% 2% 1% 2% 1% 7% Less education Potentially non-modifiable 65% Potentially modifiable 35% L a t e l i f e M i d l i f e E a r l y l i f e Hearing loss Percentage reduction in new cases of dementia if this risk is eliminated Hypertension Obesity Smoking Depression Physical inactivity Social isolation Diabetes 8% 9% 5% % 4% 3% 2% 1% 2% 1% 7% Less education Potentially non-modifiable 65% Potentially modifiable 35% The best science for better lives The Lancet Commission presents a new life-course model showing potentially modifiable, and non-modifiable, risk factors for dementia. ApoE ε4 allele Risk factors for dementia

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5%

Birth

Hearing loss

Hypertension

Obesity

Smoking

Depression

Physical inactivity

Low social contact

Diabetes

8%

9%

5%

4%

3%

2%

1%

2%

1%

7%

Less education

Potentiallynon-modifiable

65%

Potentiallymodifiable

35%

Late life

Midlife

Early lifeHearing loss

Percentage reduction in new cases of dementiaif this risk is eliminated

HypertensionObesity

Smoking

DepressionPhysical inactivity

Social isolationDiabetes

8%

9%

5%

%

4%

3%

2%

1%

2%

1%

7%

Less education

Potentiallynon-modifiable

65%

Potentiallymodifiable

35%

The best science for better lives

The Lancet Commission presents a new life-course model showingpotentially modifiable, and non-modifiable, risk factors for dementia.

ApoE ε4 allele

Risk factors for dementia