Publish Date : Feb 2014 No of Pages: 140

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RNA Based Therapeutics Market

Introduction

• RNA Based Therapeutics Market Report, published by Allied MarketResearch, forecasts that the global market is expected to garner $1.2 billionby 2020, registering a CAGR of 28.4% during the period 2014-2020.Due to itsability to render targeted solutions for chronic diseases such as cancer, AIDS,rare genetic disorders, and certain cardiovascular conditions, RNA basedtherapeutics is expected to significantly impact the global pharmaceuticalindustry.

• The large scale funding from public and private sector, growing interest ofpharmaceuticals and biotech giants for developing novel deliverytechnology, and anticipated saving in healthcare expenditure are propellingthe growth of RNA therapeutics market. Moreover, the platformtechnologies such as RNAi and antisense have enabled researchers toaccelerate their research activities by defining gene sequences for chronicdiseases. Companies have widened the research focus on RNA based drug aswell, which has fueled the growth of the overall RNA therapeutics market.

Current and Future Market Scenario

The government of the United States, through its National Institute of Health(NIH), provides funds for RNA therapeutics research, thus assist in propellingthe growth of this market. To boost the research activities the U.S. FDA isproviding fast track designation to the RNA products, which are in thepipeline.

The study suggests that the enabled technologies such as RNA interferencetechnology (RNAi) and RNA antisense technology will dominate the marketwith RNAi technology getting interest from most of the participants. Thedevelopment pipeline suggests that oncology segment will emerge as thelargest application segment. This is largely due to the high prevalence of suchdiseases and limited efficiency of available therapeutics in treating suchdiseases. Research and therapeutics are the two major end-use segments ofRNA therapeutics market. North America currently commands the lion'sshare of the market as most of the research and development activity isconcentrated in this region. However, Asia Pacific and other emerging regionswill gradually catch-up over the forecast period.

RNA Based Therapeutics Market - Segments

MARKET BY TECHNOLOGY

• Enabling technologies Microarrays Labeling Purification Linear amplification qRT-PCR Inhibition

• Enabled technologies RNA Interference (RNAi) technologies Small interfering RNA (siRNA) MicroRNA (miRNA)

RNA antisense technologies

RNA Based Therapeutics Market - Segments

• MARKET BY APPLICATION

Cardiovascular Kidney Diseases Oncology Infectious diseasesMetabolic disorders Others

• MARKET BY END USERS Research Therapeutics Diagnosis

Leading Players

• The Key companies in this space are Alnylam Pharmaceuticals,Inc., Benitec Biopharma Limited, Cenix BioScience GmbH,Dicerna Pharmaceuticals, Inc., Genzyme Corporation, ISISpharmaceuticals Inc., Quark Pharmaceuticals, Inc., SilenceTherapeutics PLC, and Tekmira Pharmaceuticals Corp. Theseorganizations have raised funds from private and public sectorsto bear the high cost of RNA therapeutics research.

• Though the clinical results behind RNA based therapeutics arecompelling, the Pharma and biotech companies are still workingto identify opportunistic areas to grow. It is most likely that theRNA therapeutic companies would successfully tackle the drugdelivery issue, which is the major hurdle in commercialization ofthesetherapeutics and at the same time would reap benefits.

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