s113 shine better than squeaky clean e powerpoint

8/9/2019 S113 SHINE Better Than Squeaky Clean E Powerpoint

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WATER PURIFICATION


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WATER PURIFICATION

We all need clean water, water that isfree of potentially dangerouscontaminants.

For our homes we need basic clean andsanitary water. Water that can be usedfor cooking, cleaning and bathing. Waterthat meets or exceeds the purity

standards of our local governments. Forbio-pharmaceutical uses, the water usedmust meet a much higher standard.


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WATER PURIFICATION

Bio-pharmaceutical manufacturinguses Water For n!ection" #WF$. WFis considered to be %&&' water. (his

water is free of sediment, minerals,and organic contamination. WF is typically contained in stainless

steel systems, heated to temperatures

!ust below boiling, and pumpedthrough systems to the point of usethat will not allow dead )ones wherethe water does not circulate.


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WATER PURIFICATION

WF is used to clean water resistantmanufactured medical e*uipmentsuch as syringes. +nder highpressure it is sprayed on thise*uipment, used to soak it, andin!ected into the internal parts of the

e*uipment.


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WATER PURIFICATION

n our homes we might have a sediment lter toremove fairly large particles suspended in thewater. ur cars have a sediment lters for oil.

ediment lters for water typically use a cloth orpaper lter cartridge. /s the water 0owsthrough large sediment particles are removedfrom the water. ediment removal is fre*uentlythe rst step in making WF.

Photograph from Wiki Media Commons


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WATER PURIFICATION

f the water coming into our homes was tobe used to make WF and has someunwanted biologic residue, chlorine, or afoul odor then a second lter is added. (hesecond lter will be activated charcoal.

/ctivated charcoal willnot

remove sodium 0uorideor

nitrates.Photograph from Wiki Media Commons


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WATER PURIFICATION

Typically the two canisters for the filtersare connected in simple series. Filter

canisters used in our homes are small; a few

inches in diameter and less than a foot long.

Those used in WFI production

for io!pharmaceutical

manufacturing are much larger.Photograph from Wiki Media Commons


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WATER PURIFICATION

ome locations have water very highin mineral content. (hese locationswill add an ion exchange lter to

their series of lters.

Photograph from Wiki Media Commons

(hese beads are made of presin and can be charged

attract specic ions.


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WATER PURIFICATION

/ water softener is an ion exchange lter toremove scale producing calcium andmagnesium from water.

Water softeners use special resin# smallplastic beads$ that attract calcium andmagnesium ions.

Water softeners cycle periodically to

recharge1 they 0ush the residue with saltwater to remove #rinse away$ unwantedions. (his rinse water is discarded.


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WATER PURIFICATION

/nother device that is added to waterpurication systems in some homes andin biopharmaceutical manufacturing

plants is a reverse osmosis lter. (his device forces water to move

against the normal direction of osmosisthrough a semi-permeable membrane.

(he reverse osmosis re*uires highpressure to move water through thelter.


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WATER PURIFICATION

2everse osmosis removes bacteria,spores and viruses from water.

Water after being run through thereverse osmosis membrane is very,very clean. (he water before themembrane will have a built up of

unwanted particles and must becycled #0ushed out$ periodically.


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WATER PURIFICATION


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WATER PURIFICATION

n the production of water for in!ection for

bio-pharmaceutical manufacturing has anadditional stage, distillation.

3istillation heats water to its boiling point,creates vapor which passes through acooling system, and re-condenses back to

li*uid water. Water after the distillationprocess is %&&' water.


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WATER PURIFICATION

Water for in!ection is kept at hightemperatures and is used for a very completecleaning of medical products. /ny small

amount of remaining manufacturing residueand biological contaminants are completelycleaned from the product. (he product is nowready for clean-room packaging and sealing.

4edical products, such as syringes, aresterili)ed by gamma radiation after packaging.

s113 shine better than squeaky clean e powerpoint

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