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SBC322 Ecological and Evolutionary Genomics [email protected]

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SBC322 Ecological and Evolutionary Genomics

[email protected]

This changes everything.454

IlluminaSolid...

Any lab can sequence anything!

How does this change affect us regarding ecology & evolution

research?

(1/2) Merging of molecular and eco/evo approaches

• identifying genes & mechanisms underlying: • phenotypes (behaviors, morphologies, physiologies…)• constraints• responses to changing environments

• …

(2/2) Novel approaches for

• relationships between species• relationships within species• species distributions• life histories• biodiversity assessments• evolutionary histories

Very challenging. exciting.

Aims (1/2)

To understand and critically evaluate:

• research questions

• methods

• experimental designs

• applications

in ecological and evolutionary genomics.

Aims (2/2)Improving skills:

•critically reading scientific literature

•understanding interdisciplinary science

•oral scientific communication (formal & informal)

•written scientific communication (blog & exam)

Understanding:

•the peer review process for scientific publication

Science-driven.

Interactive

• Small groups - informal presentations

• Formal presentations in pairs

• Blog posts

• Peer review

ok?

Yannick Wurm

YW

Christophe Eizaguirre

CE

Main themes

1. Methods

2. Social evolution

3. Conservation

4. Genome dynamics

5. Speciation

Schedule

(work in progress; on qmplus)

Evaluation25%: Class participation (in class + blogging + presentations)

75%: essay exam

Reading a paper

Reading a paper

Sequence of events:

• Title

• Abstract

• Figures/Subtitles

• Main text

• (iterate)

Additional Guidelines• Read critically

• authors aren’t always correct. • Instead, be suspicious

• Read creatively• what are the good ideas?• what improvements could make important differences?

• Make notes• underline/annotate/markup key points• questions/ambiguities/criticisms

• After first read, summarise in 1-2 sentences• then extend summary

• Compare to other works

• a one or two sentence summary of the paper.• a deeper, more extensive outline of the main

points of the paper, including for example assumptions

• made, arguments presented, data analyzed, and conclusions drawn.

• any limitations or extensions you see for the ideas in the paper.

• your opinion of the paper; primarily, the quality of the ideas and its potential impact.

Reading a paper / notes