sbi4u-nov 26,2012 kidney disease. diabetes insipidus (di) destruction of adh-producing cells of the...
TRANSCRIPT
SBI4U-NOV 26 ,2012
Kidney Disease
Diabetes Insipidus (DI)
Destruction of ADH-producing cells of the hypothalamus or destruction of hypothalamus-pituitary nerve tracts.
Frequent urination ( 20L/day) & excessive thirst.
Rare disease.
Diabetes Mellitus
Insulin deficiency or resistance- Proximal convoluted tubule can absorb up to
0.1 % blood sugar.Excess sugar in nephron
Bright’s Disease &Nephritis
Nephritis is not a single disease
One type of nephritis affects glomerulus
Altering nephron’s permeability
Kidney Stones
Caused by percipiration of mineral solutes from blood.
Categorized as either alkaline or acid stones.
ESWL (Extracorporealshock wave lithotripsy)
Dehydration
Excessive loss of water (also solutes)Decrease in plasma blood volume3 types: hypotonic,hypertonic, isotonic
dehydrationNeurological complications
FYI ONLY
Healthy Body Water in Women & Men respectively
Body Fat % Body Water %
4-20% 58-70%
21-29% 52-58%
30-32% 49-52%
33%+ 37-49%
Female Body Water Chart
Body Fat % Body Water %
4-14% 63-70%
15-21% 57-63%
22-24% 55-57%
25%+ 37-55%
FYI ONLY
Kidney Disease Cause of problem
Problem created by disease
Recommended treatment
Diabetes Mellitus
Lack of insulin production
Glucose in urine causing dehydration
Healthy dietExercise for type 2Insulin injection
Diabetes Insipidus
Destruction of ADH producing cells in brain
Decrease in H20 reabsorption and increase in urine production (20l/day)Extreme thirst
ADH provided by injection
Bright’s Disease Inflammation of nephron (one type of nephritis)Invading microbes destroys blood vessels of nephron
Proteins and large molecules are able to pass into the nephron.Increase in urine output
No treatment
Kidney Stones Precipitation of mineral solutes from the blood
Pain (extreme) SurgerySound waves treatment if small
Alcohol is an antidiuretic , a substance that increases the production of urine. Alcohol also suppresses the production and release of ADH. Should people who are prone to developing kidney stones consume alcohol? Explain.