7/28/2019 Schizophrenia Diagram.docx

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Schizophrenia Schematic Diagram

Precipitating Factors:

*Environment*Immuno-virologic

Prediscposing Factors:

*Genetics

*Neuro-Anatomy

*Neuro-Chemical

*Unknown

Neuro-Anatomy:

*Decreased brain

tissue and cerebo-

spinal fluid

*Ventricle

enlargement

*Cortical atrophy

*Diminished glucose

metabolism at the

frontal area

Neuro-Chemical:

*Increased

Dopamine

*Increased

Serotonin

*Excessive

neurotransmitters

*Viral Exposure

*Cytokine

inflammatory

mediator increase

*Cold

environments*Triggers

Neuro-chemical

changes

Changes in neural activity:

Symptoms

Positive (Hard)

Symptoms:

*Associative Looseness

*Ambivalence

*Delusions

*Flight of Ideas

*Echopraxia

*Hallucinations

*Ideas of Reference

*Perseveration

Negative (Soft)

Symptoms

*Alogia

*Apathy

*Blunt Affect

*Catatonia

*Flat Affect

*Lack of Volition

*Anhedonia