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SCIENTIFICPROGRAMME

Focus joint sessions

Scientific programme endorsed by

MiCo Congress Center | 16-19 October 2018 MILANO

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14:30 IMPROVE YOUR SKILLS 15:40 COMPLEX SETTINGS IN LAA OCCLUSION Chairpersons: Gian Battista Danzi (Pietra Ligure), Antonio Rapacciuolo (Napoli)

14:30 Lecture: Current status and unmet needs of left atrial appendage Oocclusion Luigi Vignali (Parma)

14:40 Clinical case: Complex LAA anatomy Alberto Ranieri De Caterina (Massa)

14:46 Discussion

14:56 Clinical case: Complex septal anatomy Elvis Brscic (Torino)

15:02 Discussion

15:12 Clinical case: LAA with suspected thrombus Gianpiero D’Amico (Padova)

15:18 Discussion

15:28 Tips and tricks Francesco Meucci (Firenze)

Experts: Francesco Borgia (Napoli), Francesco Caprioglio (Mestre), Marco Ciardetti (Pisa), Emanuela De Cillis (Bari), Francesca Lanni (Avellino), Paolo Magnavacchi (Baggiovara)

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15:40 IMPROVE YOUR SKILLS16:50 THE CHOICE OF THE ACCESS IS THE KEY TO PROCEDURAL SUCCESS! Chairpersons: Luigi Salemme (Mercogliano), Giuseppe Sangiorgi (Bergamo)

15:40 Lecture: How to choose the right vascular access and avoid complications Fausto Castriota (Bergamo)

15:50 Clinical case: Radial approach for CAS Piero Montorsi (Milano)

15:56 Discussion

16:06 Clinical case: Management of large sheaths for bulky devices Salvatore Saccà (Mirano)

16:12 Discussion

16:22 Clinical case: Retrograde access for peripheral CTO Paolo Sbarzaglia (Cotignola)

16:28 Discussion

16:38 Tips and tricks Marco De Carlo (Pisa)

Experts: Giuseppe Caramanno (Agrigento), Fortunato Iacovelli (Bari), Antonio Pitì (Seriate), Armando Pucciarelli (Mercogliano), Antonio Trivisonno (Campobasso), Giuseppe Vadalà (Palermo)

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14:30 CLINICAL FORUM15:40 CHIPS: DEFINING AND TREATING COMPLEXITY Chairpersons: Paolo Rubartelli (Genova), Nicola Signore (Bari)

14:30 Lecture: Who is CHIP, the patients or the procedure? Carlo Briguori (Napoli)

14:40 Clinical case: Protected PCI Claudio Larosa (Andria) Challengers: Enrico Passamonti (Cremona), Antonio Saino (Seriate)

15:00 Clinical case: Last remaining vessel. How to deal with it? Domenico Tavella (Verona) Challengers: Matteo Bianco (Orbassano), Gabriele Gasparini (Rozzano)

15:20 Clinical case: Unprotected left main lesion +3 vessel disease refused by cardiac surgeon Angela Ferrara (Bari) Challengers: Elena Guerra (Treviso), Alessio Gaetano La Manna (Catania)

15:40 CLINICAL FORUM 16:50 THE ART AND SCIENCE OF CLOSING HOLES Chairpersons: Mario Carminati (San Donato Milanese), Eustaquio Onorato (Bergamo)

15:40 Lecture: Percutaneous closure of patent foramen ovale: 2018 update Christian Pristipino (Roma)

15:50 Clinical case: Deviceless mediated PFO closure: when to do and when don’t Achille Gaspardone (Roma) Challengers: Massimo Chessa (San Donato Milanese), Antonio Rapacciuolo (Napoli)

16:10 Clinical case: PFO with large aneurism Giuseppe Santoro (Massa) Challengers: Gianfranco Butera (San Donato Milanese), Annunziata Nusca (Roma)

16:30 Clinical case: PFO ICE guided Miroslava Stolcova (Firenze) Challengers: Antonio Dellavalle (Alba), Paolo Scacciatella (Torino)

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14:30 EXPERT DEBATE15:40 OPEN CHALLENGES IN CAD TREATMENT Chairpersons: Maurizio Cappelli Bigazzi (Napoli), Cesare Greco (Roma)

CONTROVERSY 1: RECURRENT ANGINA WITH NON-OBSTRUCTIVE CAD

14:30 A flawed entity and drugs treatment options Gianpaolo Niccoli (Roma)

14:38 Still room to improve diagnosis and (percutaneous) treatment

Francesco Giannini (Milano)

14:46 Discussion

CONTROVERSY 2: DEALING WITH IN-STENT RESTENOSIS

14:53 Drug-eluting balloons should be preferred: why, when, how Stefano Galli (Milano)

15:01 New-generation DES are better why, when, how Gioel Grabrio Secco (Alessandria)

15:09 Discussion

CONTROVERSY 3: SPONTANEOUS CORONARY DISSECTIONS

15:16 Conservative treatment why, when Emanuela Piccaluga (Milano)

15:24 Interventional treatment why, when Battistina Castiglioni (Varese)

15:32 Discussion

Discussants: Matteo Aquilina (Ravenna), Giorgio Caretta (La Spezia), Federico Conrotto (Torino), Stefano Ferraro (Piacenza), Francesca Giovannelli (Roma), Filippo Russo (Como), Marco Turri (Castiglione delle Stiviere)

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15:40 EXPERT DEBATE 16:50 ASSOCIATION OF ANTIPLATELET AND ANTICOAGULANT DRUG IN COMPLEX

CLINICAL SETTINGS Chairpersons: Plinio Cirillo (Napoli), Michele Massimo Gulizia (Catania)

CONTROVERSY 1: NEW-ONSET AF IN PATIENTS UNDERGOING COMPLEX CORONARY STENTING

15:40 Dual antithrombotic therapy is the right choice: beware of bleeding risk Piera Capranzano (Catania)

15:48 Triple therapy is the right choice beware of ischemic risk Fabrizio D’Ascenzo (Torino)

15:56 Discussion

CONTROVERSY 2: NSTEMI PATIENTS WITH DIFFUSE CORONARY ANEURYSM/ECTASIA

16:03 DAPT with ASA and ticagrelor – without exception Giuseppe Gargiulo (Napoli)

16:11 SAPT and NOAC - why, when, how Giuseppe Patti (Roma)

16:19 Discussion

CONTROVERSY 3: ANTITHROMBOTIC THERAPY IN PATIENTS WITH CONCOMITANT CAD AND PAD 16:26 DAPT

Giulia Magnani (Parma)

16:34 SAPT-OAC Ferdinando Varbella (Rivoli)

16:42 Discussion

Discussants: Leonardo Abbracciavento (Taranto), Marianna Adamo (Brescia), Marco Caruso (Palermo), Stefano Garducci (Vimercate), Riccardo Neri (Pordenone), Enrico Romagnoli (Roma), Claudia Tamburino (Catania)

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14:30 CONSENSUS-SEEKING DECISION-MAKING15:40 DIAGNOSIS AND TREATMENT OF STABLE CORONARY ARTERY DISEASE Chairpersons: Andrea Celestini (Viterbo), Renato Valenti (Firenze)

14:30 Clinical case: patient with stable angina Antonio Maria Leone (Roma)

14:35 Expert #1: Non invasive tests remains the standard (clinical point of view) Pasquale Perrone Filardi (Napoli)

14:43 Expert #2: Invasive approach should always be preferred (interventionalist /surgeon point of view) Maurizio Tespili (Milano)

14:51 Case solution Antonio Maria Leone (Roma)

14:56 Moderated Discussion to Consensus

15:05 Clinical case: Follow-up after coronary stenting Niccolò Brenno Grieco (Milano)

15:10 Expert #1: A dedicated follow-up is mandatory: the post PCI registry results Luigi Oltrona Visconti (Pavia)

15:18 Expert #2: A dedicated follow-up is not mandatory Giorgio Quadri (Rivoli)

15:26 Case solution Niccolò Brenno Grieco (Milano)

15:31 Moderated Discussion to Consensus

Experts: Andrea Celestini (Viterbo), Francesco Della Rovere (Genova), Fabio Ferrari (Orbassano), Arian Frasheri (Trapani), Daniele Giacoppo (Palermo), Franco Prosperi (Teramo), Antonio Varveri (Roma)

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15:40 CONSENSUS-SEEKING DECISION-MAKING 16:50 VALVE IN VALVE Chairpersons: Claudio Moretti (Torino), Gian Paolo Ussia (Roma)

15:40 Clinical scenario: Degenerated mitral bioprosthesis Federico Ronco (Mestre)

15:45 Percutaneous trans-septal approach Azeem Latib (Milano)

15:53 Surgical transapical approach Paolo Denti (Milano)

16:01 Case solution Federico Ronco (Mestre)

16:06 Moderated Discussion to Consensus

16:15 Clinical scenario: Degenerated, small aortic bioprosthesis Carmine Musto (Roma)

16:20 Simple VIV approach is enough Salvatore De Rosa (Catanzaro)

16:28 Surgical/percutaneous enlargemnet is the approach Giuseppe Bruschi (Milano)

16:36 Case solution Carmine Musto (Roma)

16:41 Moderated Discussion to Consensus

Experts: Giovanna Erente (Vicenza), Luciano Fattore (Aversa), Ida Monteforte (Napoli), Michele Romano (Mantova), Roberta Rosso (Novara), Giovanni Sorropago (Monza), Giancarlo Vitrella (Trieste)

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14:30 CLINICAL CASES 115:40 Chairpersons: Flavia Belloni (Roma), Luca Golino (Aversa)

15:40 CLINICAL CASES 216:50 Chairpersons: Giuseppe Andolina (Palermo), Giuseppe Migliore (Palermo)

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14:30 STEP BY STEP TUTORIAL15:40 CALCIFIC LESIONS Facilitators: Roberto Garbo (Torino), Jacopo Oreglia (Milano)

Media Driver: Chiara Bernelli (Pietra Ligure)

14:30 Patients selection Fundamentals

14:50 Interaction with audience

15:00 Step-by-step procedure

15:20 Discussion

15:30 Procedure wrap-up

15:40 STEP BY STEP TUTORIAL16:50 HOW TO APPROACH CTO REVASCULARIZATION: ANTEGRADE, RETROGRADE Facilitators: Andrea Gagnor (Torino), Alessio Gaetano La Manna (Catania) Media Driver: Silvio Fedele (Roma)

15:40 Patients selection fundamentals

16:00 Interaction with audience

16:10 Step-by-step procedure

16:30 Discussion

16:40 Procedure wrap-up

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14:30 IMPROVE YOUR SKILLS 15:40 TAVI IN BICUSPID AORTIC STENOSIS VALVE: A BUMPY ROAD Chairpersons: Alessandro Bortone (Bari), Maurizio D’Amico (Torino)

14:30 Lecture: Current status and unmet needs in bicuspid aortic Vunmet needsalve stenosis Anna Sonia Petronio (Pisa)

14:40 Clinical case 1: The importance of sizing Bernhard Reimers (Rozzano)

15:46 Discussion

14:56 Clinical case 2: The importance of valve choice Caterina Gandolfo (Palermo)

15:02 Discussion

15:12 Clinical case 3: The importance of positioning Chiara Fraccaro (Padova)

15:18 Discussion

15:28 Tips and tricks Massimo Medda (Milano)

Experts: Omar Di Gregorio (Cuneo), Piermichele Grassi (Taranto), Enrico Franceschini Grisolia (Belluno), Francesca Ristalli (Firenze), Orazio Valsecchi (Bergamo)

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15:40 CLINICAL CASE MIX 16:50 Chaipersons: Giulio Guagliumi (Bergamo), Giulio Speciale (Roma)

15:40 Clinical Case 1 Salvatore Geraci (Agrigento)

15:45 How should I treat Alfonso Ielasi (Milano)

15:50 Case solution Salvatore Geraci (Agrigento)

15:55 Discussion

16:03 Clinical Case 2 Micaela Conte (Latina)

16:08 How should I treat Alberto Polimeni (Catanzaro)

16:13 Case solution Micaela Conte (Latina)

16:18 Discussion 16:26 Clinical Case 3

Farhat Fouladvand (Sofia - BG)

16:31 Critical rebuttal and solution Michele Occhipinti (Varese)

16:36 Case solution Farhat Fouladvand (Sofia - BG)

16:41 Discussion

Discussants: Francesco Bonechi (Empoli), Francesco Casilli (Milano), Katya Vitina Lucarelli (Aquaviva delle Fonti), Pier Giuseppe Greco Lucchina (Moncalieri), Mariano Pellicano (Allst - B), Nicola Pellizzari (Castelfranco Veneto), Fabio Piazza (Savigliano)

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14:30 ORAL COMMUNICATIONS15:00 STRUCTURAL INTERVENTION 1 Chairpersons: Marianna Adamo (Brescia), Giovanni Esposito (Napoli)

15:00 ORAL COMMUNICATIONS15:30 PHARMACOLOGY Chairpersons: Angelo Anzuini (Castellanza), Giuseppe Musumeci (Cuneo)

15:30 ORAL COMMUNICATIONS 16:00 AORTIC VALVE DISEASE Chairpersons: Giulio Giuseppe Stefanini (Rozzano), Giuseppe Tarantini (Padova)

16:00 ORAL COMMUNICATIONS 16:30 STRUCTURAL INTERVENTION 2 Chairpersons: Sergio Berti (Massa), Francesco Borgia (Napoli)

16:30 ORAL COMMUNICATIONS 16:50 MITRAL INTERVENTION Chairpersons: Giorgio Baralis (Cuneo), Antonio Rapacciuolo (Napoli)

ED. VILLAGE - CORNER F

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16:50 18:30

SOSTENIBILITÀ DEL SSN: IL RUOLO DEL GISE NELL’ACCESSO ALLE CURE PER LA MIGLIOR RISPOSTA TERAPEUTICA DEI PAZIENTI

PATIENT, VALUE ACCESS AND SUSTAINABILITY: THE ROLE OF GISE Chairperson: Mario Sechi, Giornalista

Participants

On. Rossana Boldi, Vice Presidente XII Commissione Affari Sociali, Camera dei Deputati

Sen. Paolo Sileri, Presidente XII Commissione Sanità Senato*

Giuseppe Tarantini, Presidente GISE

Battistina Castiglioni, Consigliere GISE

Michael F. Mahoney, CEO, Boston Scientific

Lorenzo Mantovani, Università degli Studi di Milano-Bicocca

Carlo Nicora, Direttore Generale ASST Papa Giovanni XXIII, Bergamo

*È stato invitato a partecipare

18:30 GISE ANNUAL MEETING20:00

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08:00 LIVE CASES09:30 from Ospedale Civile Annunziata Cosenza and ASST Carlo Poma Mantova Coordinator from Cosenza: Francesco Greco Resident Operators: Roberto Caporale, Federico Battista, Daniela Chiappetta,

Angelo Leone Coordinator from Mantova: Corrado Lettieri Resident Operators: Michele Romano, Stefano Pirrelli, Nicola Camurri Chairperson: Giovanni Esposito (Napoli) Co-chair: William Wijns (Galway - IRL) Webmoderator: Margherita D’Anna (Cinisello Balsamo) Factoid: Gianluca Caiazzo (Aversa) Commentators: Francesco Bovenzi (Lucca), Roberto Diletti (Rotterdam - NL),

Michael Haude (Neuss - D), Stefano Rigattieri (Roma), Andrea Rognoni (Novara), Fabio Felice Tarantino (Forlì)

Clinical Anatomical Correlation: Cristina Basso (Padova)

09:30 OPENING CEREMONY10:00 Welcome from PCR - William Wijns (Galway - IRL) Welcome from incoming President of EAPCI - Dariusz Dudek (Krakow - PL) Welcome from President of GISE - Giuseppe Tarantini (Padova)

10:00 LIVE CASES11:20 from Ospedale Civile Annunziata Cosenza and ASST Carlo Poma Mantova Coordinator from Cosenza: Francesco Greco Resident Operators: Roberto Caporale, Federico Battista, Daniela Chiappetta,

Angelo Leone Coordinator from Mantova: Corrado Lettieri Resident Operators: Michele Romano, Nicola Camurri Chairperson: Giuseppe Musumeci (Cuneo) Co-chair: Dariusz Dudek (Krakow - PL) Webmoderator: Irene Pescetelli (Ponderano) Factoid: Filippo Zilio (Trento) Commentators: Martine Gilard (Brest - F), Ciro Indolfi (Catanzaro),

Ugo Limbruno (Grosseto), Alfredo Marchese (Bari), Ciro Mauro (Napoli), Joao Brun Silveira (Porto - P)

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11:20 JOINT SESSION GISE - EAPCI - PCR 12:40 Chairpersons: Dariusz Dudek (Krakow - PL), Giuseppe Tarantini (Padova),

William Wijns (Galway - IRL)

11:20 Novel findings in percutaneous revascularization of patients with stable angina Emanuele Barbato (Napoli)

11:30 Patients at high bleeding risk: which revascularization strategy, which stent Jean Fajadet (Toulouse - F)

11:40 Update on TAVI in patients at low and intermediate risk Martine Gilard (Brest - F)

11:50 Management of patients with aortic stenosis and combined coronary stenosis Michael Haude (Neuss - D)

12:00 An update on percutanoues treatments of mitral and tricuspid valve disease Sergio Berti (Massa)

12:10 Discussion Roberto Diletti (Rotterdam - NL), Martine Gilard (Brest - F), Joao Brun Silveira (Porto - P)

12:40 LIVE IN THE BOX 13:25 from Ospedale San Raffaele - Milano Coordinator: Alaide Chieffo Chairpersons: Alfredo Marchese (Bari), Ferdinando Varbella (Rivoli) Experts: Francesco Burzotta (Roma), Marco Contarini (Siracusa),

Paolo Antonio Pagnotta (Rozzano), Giampaolo Pasquetto (Monselice), Marco Luciano Rossi (Milano), Tommaso Piva (Ancona), Luca Testa (San Donato Milanese)

Webmoderator: Enrico Favaretto (Udine)

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15:00 JOINT SESSION GISE - EBC 16:10 OPTIMAL BIFURCATION TREATMENT Chairpersons: Federico Piscione (Salerno), Goran Stankovic (Belgrade - SRB)

15:00 Lecture: Current status and unmet needs of bifurcation Marco Zimarino (Chieti)

15:10 Clinical case 1 Carlo Briguori (Napoli)

15:16 Discussion

15:26 Clinical case 2 Sunao Nakamura (Chiba - J)

15:32 Discussion

15:42 Clinical case 3 Alfredo Marchese (Bari)

15:48 Discussion

15:58 Tips and tricks on bifurcation treatment Francesco Burzotta (Roma)

Experts: Paolo Calabria (Grosseto), Antonino Cardile (Treviglio), Nadia Garro (Siracusa), Simone Muraglia (Trento), Salvatore Notaristefano (Perugia), Massimo Siviglia (Reggio Calabria)

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16:10 IMPROVE YOUR SKILLS 17:20 FRONTIERS IN MITRAL PERCUTANEOUS THERAPY Chairpersons: Alberto Cremonesi (Bergamo), Roberto Violini (Roma)

16:10 Lecture: Current status and unmet needs of Percutaneous mitral repair Federico De Marco (San Donato Milanese)

16:20 Clinical case: Primary mitral regurgitation

Luigi Fiocca (Bergamo)

16:26 Discussion

16:30 Clinical case: Functional mitral regurgitation Cesare Baldi (Salerno)

16:36 Discussion

16:40 Clinical case: Minimally invasive percutaneous ventricular reshaping Mauro Biffi (Bologna)

16:46 Discussion

16:52 Clinical case: Percutaneous annuloplasty Carmelo Grasso (Catania)

16:58 Discussion

17:08 Tips and tricks Carmelo Grasso (Catania)

Experts: Alfonso Alfieri (Caserta), Maurizio Cappelli Bigazzi (Napoli), Alfredo Cerillo (Massa), Riccardo Colantonio (Roma), Luisa Morena (Cuneo), Renato Rosiello (Mantova)

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17:20 IMPROVE YOUR SKILLS 18:30 CONTEMPORARY TREATMENT OF SEVERELY CALCIFIED CORONARY LESIONS Chairpersons: Matteo Montorfano (Milano), Claudio Rapetto (Sanremo)

17:20 Lecture: Current status and unmet needs Giacomo Boccuzzi (Torino)

17:30 Clinical case: The role of dedicated balloon Dionigi Fischetti (Lecce)

17:36 Discussion

17:46 Clinical case: The role of shockwave coronary Rx lithoplasty Carlo Di Mario (Firenze)

17:52 Discussion

18:02 Clinical case: All you needed is Rotablation Massimo Mancone (Roma)

18:08 Discussion

18:18 Tips and tricks Andrea Santarelli (Rimini)

Experts: Marco Balducelli (Ravenna), Gerardo Carpinella (Napoli), Sebastian Cinconze (Castellanza), Michael Donahue (Roma), Cataldo Loiodice (Matera), Mauro Pennacchi (Tivoli), Antonio Rubino (Palermo)

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15:00 EXPERT DEBATE16:10 TAVI: CURRENT LIMITATIONS AND FUTURE PERSPECTIVES Chairpersons: Antonio Bartorelli (Milano), Arik Finkelstein (Tel Aviv - IL)

CONTROVERSY 1: IS IT TIME TO EXPLORE TAVI IN LOW RISK PATIENTS?

15:00 Yes. TAVI should challenge SAVR Corrado Tamburino (Catania)

15:08 No. We should stick to the guidelines Alessandro Iadanza (Siena)

15:16 Discussion

CONTROVERSY 2: IS THERE AN ISSUE WITH LONG-TERM THV DURABILITY?

15:23 Yes. THV degeneration is real Arnaldo Poli (Legnano)

15:31 No. THV durability data are reassuring Franco Fabbiocchi (Milano)

15:39 Discussion

CONTROVERSY 3: SHOULD I ALWAYS TREAT CONCOMITANT CAD IN TAVI PATIENTS?

15:46 Yes. Always perform PCI before TAVI Gaetano Contegiacomo (Bari)

15:54 No. Only perform PCI after TAVI in symptomatic patients with proximal lesions Giorgio Baralis (Cuneo)

16:02 Discussion

Discussants: Mauro Agnifili (Milano), Marco Angelillis (Pisa), Arcangelo Carrera (Siena), Giuliano Chizzola (Brescia), Gianni Dall’Ara (Forlì), Sebastiano Immè (Pedara), Antonio Rizza (Massa)

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16:10 CLINICAL FORUM 17:20 GISE ELDERLY PATIENTS Chairpersons: Andrea Albani (Bolzano), Angelo Sante Bongo (Novara) 16:10 Lecture: Oral antiplatelets optimization in elderly patients Luca Favero (Treviso)

16:20 Clinical case: Oral antiplatelet therapy in acute phase Alessandro Martinoni (Magenta)

Challenger: Francesco Amico (Catania), Giuseppe Andò (Messina)

16:35 Clinical case: Between Scylla and Charybdis: the challenging risk-benefit balance Anna Gonella (Cuneo) Challenger: Antonio Centola (Foggia), Marianna Spina (Desio)

16:50 Clinical case: Coronary revascularization in elderly patients Rocco Antonio Montone (Roma) Challenger: Tiziana Aranzulla (Torino), Lucia Coppini (Castellanza)

17:05 Clinical case: Long-term follow-up and prolonged DAPT Rocco Vergallo (Roma) Challenger: Francesco Sanna (Cagliari), Matteo Vercellino (Alessandria)

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17:20 ANTITHROMBOTIC THERAPY IN PATIENTS WITH ATRIAL FIBRILLATION 18:30 UNDERGOING PCI Chairpersons: Leonardo De Luca (Tivoli), Vincenzo Guiducci (Reggio Emilia)

17:20 Lecture: Optimal antithrombotic cocktail in patients with AF undergoing stenting Andrea Rubboli (Bologna)

17:30 Clinical case: Patient with acute coronary syndrome Flavia Belloni (Roma) Challengers: Marco Borghesi (Trento), Mila Menozzi (Rimini)

17:50 Clinical case: Patient at high bleeding risk Alberto Barioli (Padova) Challengers: Raffaele Scardala (Sanremo), Bernardo Tuccillo (Napoli)

18:10 Clinical case: Patient with complex coronary lesions Iacopo Tadonio (Parma) Challengers: Guido Belli (Bergamo), Simona Giubilato (Catania)

18:20 Discussion

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15:00 EXPERT DEBATE 16:10 OPTIMAL LIPIDIC CONTROL IN PATIENTS UNDERGOING PCI Chairpersons: Battistina Castiglioni (Varese), Gennaro Galasso (Salerno)

CONTROVERSY 1: OPTIMAL LDL LEVELS IN PATIENTS AT VERY-HIGH RISK

15:00 Less than 100 mg/dl or 50% reduction is enough Simona Pierini (Cinisello Balsamo)

15:08 Ultra-low LDL is the new target for high-risk patients Pasquale Perrone Filardi (Napoli)

15:16 Discussion

CONTROVERSY 2: TREATMENT AT HOSPITAL DISCHARGE IN ACS PATIENTS

15:23 Atorvastatin 80 mg plus ezetimibe is the best option Fabio Barlocco (Legnano)

15:31 Rosuvastatin 20 mg plus ezetimibe? Marco Ferlini (Pavia)

15:39 Discussion

CONTROVERSY 3: PATIENTS WITH HIGH BURDEN ATHEROSCLEROTIC DISEASE

15:46 My choice is alirocumab Roberta Rossini (Cuneo)

15:54 My choice is evolocumab Bernardo Cortese (Milano)

16:02 Discussion

Discussants: Maurizio Anselmi (San Bonifacio), Al Jabri Anees (Massa), Alessandro Capecchi (Bologna), Gianluca Caiazzo (Aversa), Maria Alberta Cattabiani (Parma), Roberta Della Bona (Roma), Alessandro Di Giorgio (Tormina)

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16:10 EXPERT DEBATE 17:20 HEART AND BRAIN Chairpersons: Paolo Golino (Napoli), Bruno Loi (Cagliari) CONTROVERSY 1: SYSTEMATIC USE OF EMBOLIC PROTECTION DEVICES IN TAVI

16:10 Pro Massimo Mancone (Roma)

16:18 Contra Carmelo Sgroi (Catania)

16:26 Discussion

CONTROVERSY 2: ANTITHROMBOTIC THERAPY AFTER TAVI

16:33 Short term DAPT Marco Barbanti (Catania)

16:41 The importance of being on NOAC Anna Franzone (Napoli)

16:49 Discussion

CONTROVERSY 3: COMBINED MITRAL REPAIR WITH LAA OCCLUSION

16:56 Rational, feasibility safety Chiara Fraccaro (Padova)

17:04 Nothing more than OAT Davide Capodanno (Catania)

17:12 Discussion

Discussants: Mario Arieti (Desenzano del Garda), Alessia Azzano (Brussels - B), Fabio Barili (Cuneo), Luciano Bassan (Bassano del Grappa), Giampiero Nobile (Bologna)

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17:20 EXPERT DEBATE18:30 CAD TREATMENT IN CHALLENGING CLINICAL SETTINGS Chairpersons: Emilio Di Lorenzo (Avellino), Giuseppe Grassi (Venezia)

CONTROVERSY 1: CAD IN TAVI PATIENTS

17:20 Preventive angioguided PCI Giulio Stefanini (Rozzano)

17:28 Driftlesses wire: advantages for complex anatomies and resting indexes Tommaso Gori (Mainz - D)

17:36 Discussion

CONTROVERSY 2: HIGH BLEEDING RISK PATIENTS

17:43 All DES are equivalent Francesco Prati (Roma)

17:51 A dedicated stent is needed Gianluca Campo (Ferrara)

17:59 Discussion

BRS: IS THERE STILL ANY HOPE?

18:06 Yes. The promise of BRS might still be fulfilled Juan Fernando Granada Solis (New York - USA)

18:14 No. Metallic DES will always remain undefeated Roxana Mehran (New York - USA)

18:22 Next generation BRS will try to challenge DES Bernardo Cortese (Milano)

Discussants: Gianfranco Aprigliano (Milano), Alessandro Aprile (Ancona), Massimo Leoncini (Sanremo), Angela Migliorini (Firenze), Francesco Saporito (Messina)

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15:00 CONSENSUS-SEEKING DECISION-MAKING16:10 UNUSUAL PRESENTATIONS IN CARDIOGENIC SHOCK Chairpersons: Patrick Hunziker (Basel - CH), Carlo Trani (Roma) 15:00 The scenario: Cardiogenic shock with biventricular dysfunction

Lorenzo Azzalini (Milano)

15:05 Bipella: when two is better than one (Interventional point of view) Federico Pappalardo (Milano)

15:13 ECMO: what else? (Clinical/Interventionalist/Surgeon point of view) Serafina Valente (Firenze)

15:21 Case solution Lorenzo Azzalini (Milano)

15:26 Moderated Discussion to Consensus

15:35 The scenario: Cardiogenic shock in a patient with severe CAD and aortic stenosis Elisa Nicolini (Ancona)

15:40 BAV-PCI: sometimes less is more (Interventional point of view) Carlo Tumscitz (Ferrara)

15:48 When to choose protected TAVI-PCI (Interventional point of view) Ester Cabianca (Vicenza)

15:56 Case solution Elisa Nicolini (Ancona)

16:01 Moderated Discussion to Consensus

Experts: Ivan Calchera (Monza), Giuseppe De Angelis (Rho), Massimo Di Marco (Pescara), Fulvio Furbatto (Napoli), Luigi Minervini (Andria), Renata Rogacka (Desio)

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16:10 CONSENSUS-SEEKING DECISION-MAKING17:20 COMBINED STRUCTURAL INTERVENTIONS Chairpersons: Tiziana Attisano (Salerno), Paolo Rubino (Pomigliano D’Arco)

16:10 Clinical case: Severe aortic valve stenosis and mitral regurgitation Carmen Spaccarotella (Catanzaro)

16:15 TAVI only Andrea Berni (Roma)

16:25 Planned combined intervention Gian Paolo Ussia (Roma)

16:35 Case solution Carmen Spaccarotella (Catanzaro)

16:40 Moderated Discussion to Consensus

16:45 Clinical case: Mitral and tricuspid regurgitation in left heart valve disease Cosmo Godino (Milano)

16:50 Wait & see is not enough Gabriele Pesarini (Verona)

17:00 Different percutaneous options Francesco Bedogni (San Donato Milanese)

17:10 Case solution Cosmo Godino (Milano)

17:15 Moderated Discussion to Consensus

Experts: Carlo Cicerone (Palermo), Gaetano Contegiacomo (Bari), Paolo Danna (Milano), Nicola Maddestra (Chieti), Massimo Napodano (Padova), Antonio Tondo (Lecce)

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17:20 CONSENSUS-SEEKING DECISION-MAKING 18:30 CONTROVERSIES IN CEREBROVASCULAR DISEASE Chairpersons: Antonino Nicosia (Ragusa), Tullio Nicola Tesorio (Mercogliano)

17:20 Asymptomatic carotid artery stenosis: why is so complex? Case real life Enrico Cerrato (Orbassano - Rivoli)

17:25 Interventional cardiology point of view Armando Liso (Lecce)

17:33 Medical point of view Eugenio Stabile (Napoli)

17:41 Case solution Enrico Cerrato (Orbassano - Rivoli)

17:46 Moderated Discussion to Consensus

17:55 Stroke: primary angioplasty case Giuseppe Ferrante (Rozzano)

18:00 Interventional cardiology point of view Bernhard Reimers (Rozzano)

18:08 Radiology point of view Roberto Gandini (Roma)

18:16 Case solution Giuseppe Ferrante (Rozzano)

18:21 Moderated Discussion to Consensus

Experts: Giuseppe Biondi Zoccai (Latina), Francesco Granata (Mercogliano), Adele Pierri (Salerno), Grigore Popusoi (Mercogliano), Paolo Carlo Sganzerla (Treviglio), Bruno Villari (Benevento)

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15:00 TRANSCATHETER MITRAL VALVE EDGE TO EDGE REPAIR: ITALIAN PRACTICE16:00 AND NETWORK Chairpersons: Carlo Di Mario (Firenze), Elisabetta Ricottini (Roma)

15:00 Survey GISE Thinkheart Alessio Mattesini (Firenze)

15:10 GIOTTO Study results: which patients are treated today in Italy Francesco Bedogni (San Donato Milanese)

15:20 Which patient should I treat? Chiara Fraccaro (Padova)

15:30 Overcoming organizational barriers: is it possible to build a network Giuseppe Musumeci (Cuneo)

15:40 Discussion: Lucia Barbieri (Milano), Anna Franzone (Napoli), Cosmo Godino (Milano), Luca Golino (Aversa), Rocco Sclafani (Perugia), Kia Vaziri Farahani (Lecce)

16:00 LIVE in The BOX 16:45 from Ospedale Cardinal Massaia - Asti Coordinator: Alessandra Truffa Giachet Chairpersons: Gavino Casu (Nuoro), Maurizio Di Biasi (Milano) Experts: Gabriele Crimi (Pavia), Leonardo Di Ascenzo (San Donà Di Piave),

Annamaria Nicolino (Pietra Ligure), David Rutigliano (Bari), Alessandro Sciahbasi (Roma), Marco Sesana (Desenzano del Garda), Emanuela Tavasci (Cremeno) Webmoderator: Paolo Vicinelli (Magenta)

16:45 CLINICAL CASES 318:30 Chairpersons: Annmaria Dachille (Brindisi), Salvatore Tolaro (Pedara)

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15:00 STEP BY STEP TUTORIAL 16:10 TAVI Facilitators: Nedy Brambilla (San Donato Milanese), Marco Barbanti (Catania) Media Driver: Cataldo Palmieri (Massa)

15:00 Patients selection Fundamentals

15:20 Interaction with audience

15:30 Step-by-step Procedure

15:50 Discussion

16:00 A novel device for large arteriotomy closure Antonio Bartorelli (Milano)

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16:10 STEP BY STEP TUTORIAL 17:35 NEW MODALITIES FOR FUNCTIONAL STENOSIS ASSESSMENT: IFR, QFR AND

MICROVASCULAR INDEXES Facilitators: Luigi Di Serafino (Napoli), Francesco Prati (Roma) Media Driver: Marco Barbierato (Mestre)

16:10 iPOSITION. Results Livio Giuliani (Chieti) 16:25 Patients selection Fundamentals

16:45 Interaction with audience

16:55 Step-by-step procedure

17:15 Discussion

17:25 Procedure Wrap-up: 2

17:35 CLINICAL CASES 418:35 Chairpersons: Gaetano Contegiacomo (Bari), Giovanni Valenti (Andria)

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15:00 JOINT SESSION GISE - PCR16:10 PCR PHYSIOLOGY FOCUS APPLIED HOW SHOULD I TREAT A PATIENT WITH LEFT MAIN STENOSIS? Chairpersons: Jean Fajadet (Toulouse - F), Giuseppe Tarantini (Padova)

15:00 Session objectives Learn how to best implement invasive coronary physiology in MVD Appraise the pitfalls and limitations of iFR/dPR/FFR Giuseppe Tarantini (Padova)

15:05 Clinical scenario and context:A stable patient with LM involvement only Alaide Chieffo (Milano)

15:10 Discussion and audience interaction

15:20 How would I treat? Joao Brun Silveira (Porto - P)

15:25 How did I treat? Alaide Chieffo (Milano)

15:30 Case consensus Giuseppe Tarantini (Padova)

15:35 Clinical scenario and context: A stable patient with LM involvement and multivessel disease Gianluca Campo (Ferrara)

15:40 Discussion and audience interaction

15:50 How would I treat the case? Michael Haude (Neuss - D)

15:55 How did I treat the case? . Gianluca Campo (Ferrara)

16:00 Case and session consensus Jean Fajadet (Toulouse - F)

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16:10 JOINT SESSION GISE - PCR17:20 PCR PHYSIOLOGY FOCUS APPLIED HOW SHOULD I TREAT A MVD PATIENT WITH ACUTE CORONARY SYNDROMES? Chairpersons: Emanuele Barbato (Napoli), William Wijns (Galway - IRL)

16:10 Session objectives Update on the available evidences on the application of invasive coronary physiology

in ACS patients Learn when and how to adopt functional assessment in non-culprit stenoses William Wijns (Galway - IRL)

16:15 Clinical scenario and context: STEMI patient with non-culprit stenosis Martine Gilard (Brest - F)

16:20 Discussion and audience interaction

16:30 How would I treat? Massimo Fineschi (Siena)

16:35 How did I treat? Martine Gilard (Brest - F)

16:40 Case consensus William Wijns (Galway - IRL)

16:45 Clinical scenario and context: Patient with MVD presenting with ACS/NSTEMI Ferdinando Varbella (Rivoli)

16:50 Discussion and audience interaction

17:00 How would I treat the case? Roberto Diletti (Rotterdam - NL)

17:05 How did I treat the case? Ferdinando Varbella (Rivoli)

17:10 Case and session consensus Emanuele Barbato (Napoli)

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17:20 JOINT SESSION GISE - PCR18:30 PCR PHISIOLOGY FOCUS APPLIED TREATMENT STRATEGIES FOR CHALLENGING CASES Chairpersons: Javier Escaned (Madrid - E), Giovanni Esposito (Napoli)

17:20 Session objectives Appraise the limitations of coronary angiography in symptomatic patients Learn how to implement invasive coronary physiology in challenging cases Javier Escaned (Madrid - E)

17:25 Clinical scenario and context: Angina with abnormal stress test and clean coronary artery Massimo Napodano (Padova)

17:35 Discussion and audience interaction

17:45 Clinical scenario and context: A stable patient with a CTO and a stenotic donor vessel Dariusz Dudek (Krakow - PL)

17:55 Discussion and audience interaction

18:05 Clinical scenario and context: A patient with aortic stenosis and intermediate coronary lesions

Gabriele Pesarini (Verona)

18:15 Discussion and audience interaction

18:25 Session evaluation and key learnings Giovanni Esposito (Napoli)

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15:00 RIGHT HEART CATHETERIZATION: TIPS AND TRICKS 16:00 Coordinator: Livio Giuliani (Chieti)

16:00 ORAL COMMUNICATIONS 16:30 PCI: LESION / PATIENT SUBSETS 1 Chairpersons: Roberto Accardi (Macerata), Paolo Russo (Torino)

16:30 ORAL COMMUNICATIONS 17:00 PCI: LESION / PATIENT SUBSETS 2 Chairpersons: Dario Formigli (Benevento), Maurizio Turturo (Bari)

17:00 ORAL COMMUNICATIONS 17:30 PHYSIOLOGY Chairpersons: Cristina Gemignani (Lucca), Giuseppe Gargiulo (Napoli)

17:30 ORAL COMMUNICATIONS 18:00 IMAGING AND PHYSIOLOGY Chairpersons: Emanuele Barbato (Napoli), Andrea Rizzi (Brescia)

18:00 ORAL COMMUNICATIONS 18:30 BRS Chairperson: Salvatore Geraci (Agrigento)

ED. VILLAGE - CORNER F

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08:00 LIVE CASES 09:30 from Ospedale del Cuore Fondazione CNR Massa and

Ospedale San Giovanni Bosco Torino Coordinator from Massa: Sergio Berti Resident Operators: Gennaro Santoro, Luigi Emilio Pastormerlo,

Alberto Ranieri De Caterina Coordinator From Torino: Roberto Garbo Resident Operators: Salvatore Colangelo, Francesco Colombo Chairperson: Antonio Colombo (Milano) Co-chair: Andreas Baumbach (London - UK) Webmoderator: Alessandro Daniotti (Treviso) Factoid: Valentina Boasi (Sanremo) Commentators: Marc Peter Bonaca (Boston - USA), Battistina Castiglioni (Varese),

Domenico Gabrielli (Fermo), David Moliterno (Lexington - USA), Gioel Gabrio Secco (Alessandria),Peter Smits (Rotterdam - NL), Didier Tchétché (Toulouse - F), Daniela Trabattoni (Milano)

Clinical Anatomical Correlation: Cristina Basso (Padova)

09:30 CLINICAL TRACKS10:00 Chairpersons: Carlo Cernetti (Castelfranco Veneto - Treviso), Ugo Limbruno (Grosseto)

Commentators: Mauro De Benedictis (Torino), Francesco Meucci (Firenze), Francesco Saia (Bologna), Andrea Santarelli (Rimini), Didier Tchétché (Toulouse - F), Alessandra Truffa Giachet (Asti) Webmoderator: Daniela Spartà (Legnago)

09:30 Clinical case Massimo Napodano (Padova)

09:45 Discussion

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10:00 LIVE CASES 11:20 from Ospedale del Cuore Fondazione CNR Massa and

Ospedale San Giovanni Bosco Torino Coordinator from Massa: Sergio Berti Resident Operators: Alfredo Cerillo, Anees Al Jabri, Luigi Emilio Pastormerlo Coordinator From Torino: Roberto Garbo Resident Operators: Giacomo Boccuzzi, Fabrizio Ugo Chairperson: Giuseppe Tarantini (Padova) Co-chair: Roxana Mehran (New York - USA) Webmoderator: Maria De Vita (Forlì) Factoid: Lara Frediani (Livorno) Commentators: Steven R. Bailey (San Antonio - USA), Salvatore Brugaletta (Barcelona - E),

Emilio Di Lorenzo (Avellino), Luca Favero (Treviso), Arik Finkelstein (Tel Aviv - IL), Juan Fernando Granada Solis (New York - USA), David Moliterno (Lexington - USA)

Clinical Anatomical Correlation: Cristina Basso (Padova)

11:20 MAIN SESSION 12:30 SUBMITTING THE BEST MANUSCRIPT POSSIBLE: WHERE, WHEN,

WHY AND HOW Chairpersons: Carlo Di Mario (Firenze), Giuseppe Tarantini (Padova)

11:20 What to do if my paper is rejected? David Moliterno (Lexington - USA), Editor in Chief, JACC Cardiovasc Intervent

11:30 Good papers start planning the studies: be ambitious & cooperate with your peers Subhash Banerjee (Dallas - USA), Editor in Chief, Circulation Interventions

11:40 Why case reports still make sense and how to select them Steven R. Bailey (San Antonio - USA), Editor in Chief, Catheterization & Cardiovascular interventions

11:50 Many subspecialty journals, all growing: the interventional paradox

Davide Capodanno (Catania), Deputy-Editor, EuroIntervention

12:00 Reviewer’s perspective and the importance of writing and reviewing Steven R. Bailey (San Antonio - USA) 12:07 Oveview GISE Studies Giovanni Esposito (Napoli)

12:15 Discussion invited questions from Giuseppe Musumeci (Cuneo), Francesco Saia (Bologna), Didier Tchétché (Toulouse - F)

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12:30 BURNING DEBATES 13:30 Chairpersons: Andreas Baumbach (London - UK), Antonio Colombo (Milano),

Marc Peter Bonaca (Boston - USA)

AORTIC STENOSIS IN ELDERLY TAVI REGARDLESS RISK EVALUATION?

12:30 Yes Arik Finkelstein (Tel Aviv - IL)

12:37 No Francesco Musumeci (Roma)

12:44 Discussion and vote

WILL CULPRIT SHOCK CHANGE MY CLINICAL PRACTICE

12:50 Yes Italo Porto (Roma)

12:57 No Eberhard Grube (Bonn - D)

13:04 Discussion and vote

FAST PLATETELET INHIBITION IN ACS: IV YES OR NOT

13:10 Yes Dominick J. Angiolillo (Jacksonville - USA)

13:17 No Roxana Merhan (New York - USA)

13:24 Discussion and vote

Experts: Salvatore Brugaletta (Barcelona - E), Battistina Castiglioni (Varese), Pieter Smits (Rotterdam - NL)

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15:00 JOINT SESSION GISE - SCAI 16:10 THE GRAY ZONE IN TAVR: GUIDELINES AND PRACTICE IN THE US,

ITALY AND ELSEWHERE Chairpersons: Steven R. Bailey (San Antonio - USA), Francesco Saia (Bologna)

15:00 Current status and unmet needs of TAVR worldwide Steven R. Bailey (San Antonio - USA)

15:10 Guidelines and practice mismatch in the US kirk Kirk N. Garratt (Newark Delaware - USA)

15:20 Guidelines and practice mismatch in Italy and Europe Dariusz Dudek (Krakow - PL)

15:30 Guidelines and practice mismatch in South America Fabio Sandoli de Brito Jr (Sao Paulo -Brazil)

15:40 Discussion Marta Bande (Milano), Carlo Di Mario (Firenze), Alessandro Durante (Como),

David Moliterno (Lexington - USA), Raffaele Piccolo (Napoli)

16:00 Consensus draft Steven R. Bailey (San Antonio - USA), Francesco Saia (Bologna)

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16:10 IMPROVE YOUR SKILLS17:20 PREVENTION AND TREATMENT OF NO REFLOW POST MI Chairpersons: Giuseppe De Luca (Novara), Guido Parodi (Sassari)

16:10 Lecture: Current status and unmet needs of No reflow (or microvascular dysfunction) post-MI Filippo Ottani (Forlì)

16:20 Clinical case: High thrombotic burden-thrombus aspiration and GPI Elisabetta Ricottini (Roma)

16:26 Discussion

16:36 Clinical case: Late presentation-PICSO Intermitted coronary sinus occlusion to improve microvascular dysfunction Francesco Giannini (Milano)

16:42 Discussion

16:52 Clinical case: Circulatory assist device for complex ands high risk PCI Alessio Mattesini (Firenze)

16:58 Discussion

17:08 Tips and tricks: Drugs and devices to prevent and treat no reflow Francesco Pelliccia (Roma)

Experts: Susanna Benincasa (Rho), Marco Comeglio (Pistoia), Baldassare Doronzo (Savigliano), Dario Leosco (Napoli), Eugenio Martuscelli (Roma), Gaetano Quaranta (Nocera)

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17:20 IMPROVE YOUR SKILLS18:30 UNMET NEEDS AND NEW FRONTIERS IN PERIPHERAL VASCULAR

INTERVENTIONS Chairpersons: Vittorio Ambrosini (Avellino), Antonio Micari (Bergamo)

17:20 Lecture: Current status and unmet needs of the management of lower extremities arterial disease (LEAD) Eugenio Stabile (Napoli)

17:30 Clinical case: Restenosis after percutaneous SFA: Why is so complex? Case real life Giovanni Falsini (Arezzo)

17:36 Discussion

17:46 Clinical case: Calcified peripheral vascular disease: why is so complex? Case real life Angelo Cioppa (Mercogliano)

17:52 Discussion

18:02 Clinical case: BTK new frontiers Antonio Silvestro (Milano)

18:08 Discussion

18:18 Tips and tricks Roberto Lorenzoni (Lucca)

Experts: Alberto Benassi (Modena), Marco Boccalatte (Pozzuoli), Gaetano Esposito (Pomigliano), Alessandro Furgieri (Lecce), Vincenzo Pestrichella (Bari), Giuseppe Valva (Maddaloni)

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15:00 EXPERT’S TALKS16:10 NEW TAVI VALVES: DEVICE PARADE AND PATIENT SELECTION Chairpersons: Francesco Bedogni (San Donato Milanese), Ciro Indolfi (Catanzaro)

15:00 Lecture: Ballon expandable prosthesis: the Sapien family Matteo Montorfano (Milano)

15:10 Lecture: Self expandable prosthesis: Evolute to Horizon Mauro De Benedictis (Torino)

15:20 Lecture: Self expandable prosthesis: Portico first and second generation Federico De Marco (San Donato Milanese)

15:30 Lecture: Self expandable prosthesis: the Acurates Massimo Napodano (Padova)

15:40 Lecture: Future contenders: what’s coming on Eberhard Grube (Bonn - D)

15:50 Discussion with the experts Experts: Lucilla Riva (Cuneo), Luciano Losi (Piacenza), Diego Maffeo (Brescia),

Andrea Perkan (Trieste), Giovanni Sorropago (Monza), Davide Zanuttini (Udine)

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16:10 JOINT SESSION GISE - TCT 17:20 INTERVENTIONAL PIPELINE: WHAT’S NEW AND WHAT’S COMING IN

INTERVENTIONAL CARDIOLOGY Chairpersons: Giovanni Esposito (Napoli), Juan Fernardo Granada Solis (New York - USA)

16:10 Lecture: Unmet clinical needs in coronary and structural interventions Alberto Cremonesi (Bergamo)

16:20 Lecture: Novel developments in TAVI George Dangas (New York - USA)

16:30 Lecture: Novel developments in transcatheter mitral replacement technologies Juan Fernardo Granada Solis (New York - USA)

16:40 Lecture: Novel developments in transcatheter tricuspid interventions Juan Fernardo Granada Solis (New York - USA)

16:50 Lecture: Novel developments in bioresorbable vascular scaffolds Roxana Merhan (New York - USA)

17:00 Discussion Discussants: Joao Brun Silveira (Porto - P), Mauro Carlino (Milano),

Carlo Penzo (Ferrara), Armando Perez de Prado (Leon - E), Francesco Summaria (Roma)

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17:20 CLINICAL FORUM18:30 OPTIMAL LIPID LOWERING THERAPY IN HIGH RISK PATIENTS

Chairpersons: Tiziana Aranzulla (Torino), Plinio Cirillo (Napoli)

17:20 Lettura: Optimal lipid lowering therapy in high-risk patients Fabrizio Ugo (Torino)

17:30 Recent myocardial infarction and dyslipidemia Caterina Cavazza (Rimini) Challengers: Alessandro Lupi (Domodossola), Marco Miglionico (Roma)

17:50 PCI in a patient with statin intolerance Gaetano Gioffrè (Roma) Challengers: Emanuele Tizzani (Rivoli), Guido Vittori (Rho)

18:10 PCI in a diabetic patient with dyslipidemia Amedeo Picciolo (Lecce) Challengers: Giuseppe Talanas (Sassari), Pietro Vandoni (Monza)

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15:00 EXPERT DEBATE16:10 ANTITHROMBOTIC THERAPY IN HIGH-RISK ACS: THE ACUTE PHASE Chairpersons: Dominck J. Angiolillo (Jacksonville - USA), Alberto Menozzi (Parma)

CONTROVERSY 1: ORAL PRELOADING IS ENOUGH FOR STEMI PATIENTS UNDERGOING PRIMARY PCI?

15:00 No, an IV antiplatelet agent should always be administered during primary PCI Guido Parodi (Sassari)

15:08 Yes, preloading with oral agents is enough in most STEMI patients Roberto Caporale (Cosenza)

15:16 Discussion

CONTROVERSY 2: WHICH INTRAVENOUS ANTIPLATELET AGENT DURING PRIMARY PCI

15:23 GPI are still the first option Marco Basile (Altamura)

15:31 Cangrelor in now the best solution Fabiana Rollini (Jacksonville - USA)

15:39 Discussion

CONTROVERSY 3: TIMING FOR ORAL P2Y12 ADMINISTRATION IN NSTEMI: THE (ALMOST) NEVERENDING STORY

15:46 Pretreatment remains the best strategy in NSTEMI patients Giuseppe Gargiulo (Napoli)

15:54 Oral P2Y12 can be safely delayed after coronary angiography: waiting for DUBIUS trial Marco Mojoli (Pordenone)

16:02 Discussion Discussants: Gianni Casella (Bologna), Andrea Cuculo (Foggia),

Michele De Benedictis (Savigliano), Nicoletta De Cesare (Zingonia), Sara Giolitto (Rivoli), Roberto Adriano Latini (Milano), Fabio Mangiacapra (Roma), Nadia Mollichelli (Desio)

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16:10 EXPERT DEBATE17:20 LONG-TERM ANTIPLATELET THERAPY AFTER ACS Chairpersons: Marco Ferlini (Pavia), Giuseppe Musumeci (Cuneo)

CONTROVERSY 1: STABLE PATIENTS UNDERGOING COMPLEX PCI

16:10 You can skip aspirin and use ticagrelor alone Raffaele Piccolo (Napoli)

16:18 Life-long aspirin is still mandatory Andrea Picchi (Grosseto)

16:26 Discussion

CONTROVERSY 2: LONG-TERM DAPT DURATION IN MI PATIENTS

16:33 Most patients should continue over 12 months Marc Peter Bonaca (Boston - USA)

16:41 Most patients should stop DAPT at 12 months Italo Porto (Genova)

16:49 Discussion

CONTROVERSY 3: LONG-TERM ANTITHOMBOTIC THERAPY IN HIGH-ISCHEMIC RISK PATIENTS

16:56 Best solution is long-term aspirin Eliano Pio Navarese (Falls Curch - USA)

17:04 Why do not consider low-dose rivaroxaban with single antiplatelet agent Leonardo De Luca (Tivoli)

17:12 Discussion

Discussants: Roberto Accardi (Macerata), Giovanni Longo (Caltanissetta), Vincenzo Manganiello (Aversa), Alessandro Manzoli (Roma), Andrea Micheli (Treviglio), Maurizio Giovanni Ornaghi (Cinisello Balsamo), Vincenzo Pasceri (Roma)

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17:20 EXPERT DEBATE 18:30 CORONARY REVASCULARIZATION OPTIONS IN COMPLEX SETTINGS Chairpersons: Gino Gerosa (Padova), Antonino Granatelli (Tivoli) CONTROVERSY 1: LEFT MAIN WITH MULTIVESSEL DISEASE

17:20 PCI is my first option Emanuele Meliga (Torino) 17:28 CABG remains standard of care Claudio Grossi (Cuneo)

17:36 Discussion

CONTROVERSY 2: VESSEL DISEASE

17:43 PCI is always an option Gennaro Sardella (Roma)

17:51 CABG for complete revascularization Francesco Musumeci (Roma)

17:59 Discussion

CONTROVERSY 3: CTO

18:06 Open all Alfredo Ruggero Galassi (Catania)

18:14 Open only when indicated Massimo Fineschi (Siena)

18:22 Discussion

Discussants: Augusto D’Onofrio (Padova), Luca Grancini (Milano), Massimiliano Mariani (Massa), Pietro Mazzarotto (Lodi), Andrea Pacchioni (Mirano), Isidoro Pera (Lecco), Cristina Rolfo (Rivoli)

ROOM YELLOW 1

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15:00 CONSENSUS-SEEKING DECISION-MAKING16:10 ACUTE CORONARY SYNDROMES: CHALLENGING THE UNUSUAL Chairpersons: Salvatore Ierna (Carbonia), Andrea Pavei (Padova)

15:00 The Scenario: SCAD in a young woman Luca Testa (san Donato Milanese)

15:05 Just stent it! (Interventional point of view) Francesco Tomassini (Rivoli) 15:13 Avoid stent at all costs! (Clinical/Interventionalist/Surgeon point of view) Valeria Paradies (Bari)

15:21 Case solution Luca Testa (san Donato Milanese)

15:26 Moderated Discussion to Consensus 15:35 The Scenario: Concomitant STEMI and stroke Augustin Vecchia (Avellino)

15:40 Interventional cardiologist can fix both Carlo Cernetti (Castelfranco Veneto - Treviso)

15:48 Let the interventional radiologist fix the brain Leonardo Renieri (Firenze)

15:56 Case solution Augustin Vecchia (Avellino)

16:01 Moderated Discussion to Consensus Experts: Sebastian Coscarelli Mezzano (Belluno), Angelo Di Leo (Ciriè),

Cristian Di Russo (Roma), Vittorio Monda (Napoli), Alberto Monello (Piacenza), Altin Palloshi (Milano), Monica Verdoia (Novara)

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16:10 CLINICAL FORUM 17:20 LIPID LOWERING THERAPY IN PATIENTS RECEIVING REVASCULARISATION Chairpersons: Ciro Mauro (Napoli), Carlo Sponzilli (Milano)

16:10 Lecture: Optimal lipid lowering therapy in PCI patients Alberto Menozzi (Parma)

16:20 Clinical case: Patient with ACS requiring high dose statin plus ezetimibe Davide D’Andrea (Napoli) Challengers: Francesco De Felice (Roma), Cinzia Moncalvo (Alessandria)

16:40 Clinical case: Patient with ACS requiring PCSK9 Paolo Calabrò (Caserta) Challengers: Paolo Angelo Canova (Bergamo), Ottorino Giuseppe Catapano (Forlì)

17:00 Clinical case: Patient with stable CAD and statin intolerance requiring PCSK9 Roberta Serdoz (Rieti) Challengers: Chiara Bernelli (Pietra Ligure), Mario Bollati (San Donato Milanese)

17:20 CLINICAL FORUM 18:30 PATIENTS REQUIRING NON-CARDIAC SURGERY WITH COMPLEX CORONARY

LESION TREATED WITH STENTING < 3 MONTH Chairpersons: Sergio Leonardi (Pavia), Alessandro Locatelli (Cuneo)

17:20 Lecture: The new SAS registry Roberta Rossini (Cuneo)

17:30 Clinical case: Surgery on DAPT Daniela Lina (Parma) Challengers: Marco Centola (Milano), Elia Iorio (Acquaviva delle Fonti)

17:50 Clinical case: Early drop of P2Y12 inhibitor Nuccia Morici (Milano) Challengers: Marcella Camellini (Sassuolo), Maria Molfese (Genova)

18:10 Clinical case: Bridge with Cangrelor Giulia Masiero (Cuneo) Challengers: Irene Bossi (Milano), Orlando Piro (Napoli)

ROOM YELLOW 2

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15:00 LIVE IN THE BOX 15:45 from Ospedal Vito Fazio - Lecce Coordinator: Dionigi Fischetti Chairpersons: Livio Giuliani (Chieti), Giuseppe Tarantini (Padova) Experts: Mario Crisci (Napoli), Giuseppe De Iaco (Tricase), Sebastiano Marra (Torino),

Francesco Monti (Roma), Martino Pepe (Bari), Stefano Tondi (Modena), Gianluca Tomassoni (Teramo)

Webmoderator: Renato Maria Bianchi (Napoli)

15:45 LIVE IN THE BOX 16:30 from Azienda Ospedaliera Regionale San Carlo - Potenza Coordinator: Rocco Aldo Osanna Chairperson: Luigi My (Taranto), Leonardo Paloscia (Pescara) Experts: Guido Canali (Negrar), Fabio Dell’Avvocata (Rovigo), Enrico Fabris (Trieste),

Nicoletta Franco (Rimini), Valeria Gasparetto (Peschiera del Garda), Claudio Panciroli (Lodi), Fabrizio Tomai (Roma)

Webmoderator: Francesco Stefano Soriano (Milano)

16:30 GISE YOUNG MEET THE EDITOR 17:25 Chairpersons: Carlo Di Mario (Firenze), Giulia Masiero (Padova), Francesco Saia (Bologna)

16:30 Introducing the editor Steven R. Bailey, Editor in Chief, Catheterization & Cardiovascular interventions Carlo Di Mario (Firenze)

16:35 The greatest recent contribute of my journal to Interventional Cardiology Steven R. Bailey (San Antonio - USA)

16:50 Discussion

17:15 My experience as a young Member of the PCRonline Editorial Team Francesco Costa (Messina)

17:20 Discussion and closing remarks Francesco Saia (Bologna)

Discussants: Lucia Barbieri (Milano), Gianpiero D’Amico (Padova), Anna Franzone (Napoli), Giuseppe Marchese (Venezia), Rocco Vergallo (Roma), Giampiero Vizzari (Ragusa)

17:25 CLINICAL CASES 518:30 Chairperson: Stefano Robotti (Lavagna)

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15:00 STEP BY STEP TUTORIAL 16:10 LEFT MAIN TRUE BIFURCATION LESION OPTIMAL TREATMENT Facilitators: Antonio Colombo (Milano), Luca Nai Fovino (Padova) Media Driver: Francesco Radico (Chieti)

15:00 Patients selection fundamentals

15:20 Interaction with audience

15:30 Step-by-step procedure

15:50 Discussion

16:00 Procedure Wrap-up: 2

16:10 STEP BY STEP TUTORIAL17:20 MITRAL CLIP Facilitators: Fausto Castriota (Bergamo), Cosmo Godino (Milano) Media Driver: Maria Luisa Laudisa (Novara)

16:10 Patients selection fundamentals

16:30 Interaction with audience

16:40 Step-by-step procedure

17:00 Discussion

17:10 Procedure wrap-up: 2

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17:20 STEP BY STEP TUTORIAL 18:30 MICROAXIAL PUMP SUPPORT IN THE CATH LAB Facilitators: Marco Marini (Ancona), Paolo Pagnotta (Rozzano) Media Driver: Rosetta Melfi (Roma)

17:20 Patients selection fundamentals

17:40 Interaction with audience

17:50 Step-by-step procedure

18:10 Discussion

18:20 Procedure wrap-up: 2

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15:00 GISE Young Meeting16:10 Chairpersons: Salvatore Brugaletta (Barcelona - E),

Alessio Gaetano La Manna (Catania), Alessio Mattesini (Firenze)

15:00 Introduction Alessio Mattesini (Firenze)

15:05 Overview of the current and future projects Giulia Masiero (Cuneo)

15:10 Research Rocco Vergallo (Roma)

15:15 Networking Elisabetta Ricottini (Roma)

15:20 Training and career orientation Salvatore Brugaletta (Barcelona - E)

15:25 Discussion and Remarks

15:40 Survey presentation: The gender issues and radiation risk in cath lab Chiara Bernelli (Pietra Ligure)

15:45 Call for dreamers: What women want and men think about Alessio Mattesini (Firenze)

15:50 What women want Benedetta Tomberli (Firenze)

15:55 What men think about Domenico D’Amario (Roma)

16:00 Discussion and Closing Remarks Alessio Gaetano La Manna (Catania)

Discussants: Giovanni Longo (Caltanissetta), Giuseppe Marchese (Venezia), Giulia Masiero (Cuneo), Roberta Serdoz (Rieti), Rocco Vergallo (Roma)

ROOM ORANGE 2

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16:10 DEALING WITH NIGHTMARES17:20 Chaiperson: Guglielmo Bernardi (Pordenone), Attilio Varricchio (Nola)

16:10 Clinical Case 1 Giampiero Vizzari (Ragusa)

16:15 Critical rebuttal and solution Dionigi Fischetti (Lecce)

16:20 Case solution Giampiero Vizzari (Ragusa)

16:25 Discussion

16:33 Clinical Case 2 Mauro De Benedetto Fabrizi (Cuneo)

16:38 Critical rebuttal and solution Fabio Minicucci (Napoli)

16:43 Case solution Mauro De Benedetto Fabrizi (Cuneo)

16:48 Discussion 16:56 Clinical Case 3 Luigi Piatti (Lecco)

17:01 Critical rebuttal and solution Alessandro De Leo (Treviso)

17:06 Case solution Luigi Piatti (Lecco)

17:11 Discussion

Experts: Giacinto Calculli (Matera), Giuseppe Calligaris (Milano), Michele Coceani (Pisa), Daniele Forlani (Pescara), Francesco Lavarra (Changchun - RCP), Andrea Micheli (Treviglio), Bindo Missiroli (Catanzaro)

ROOM ORANGE 2

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17:20 GISE CLINICAL TRIALS AND REGISTRIES18:30 Chairpersons: Claudio Cavallini (Perugia), Stefano De Servi (Sesto San Giovanni) 17:20 Post-PCI Luigi Oltrona Visconti (Pavia)

17:30 PERSEO Alessandro Sciahbasi (Roma)

17:40 ERIS Carlo Penzo (Ferrara)

17:50 DUBIUS Marco Mojoli (Pordenone)

18:00 IT DISAPPEARS Marco Angellilis (Pisa)

18:10 Expert roundtable: Andrea Amato (Gravedona), Federica Baldazzi (Rimini), Cecilia Fantoni (Castellanza), Laura Gatto (Roma), Roberto Mezzanotte (Roma), Anita Paggi (Sesto San Giovanni)

ROOM ORANGE 2

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15:00 JOINT SESSION GISE - PCR 16:10 PCR IMAGING CASE BASED FOCUS APPLIED HOW SHOULD I TREAT USING “FUNCTIONAL-IMAGING” GUIDANCE? Chairpersons: Andreas Baumbach (London - UK), Giuseppe Musumeci (Cuneo) 15:00 Session objectives: Giuseppe Musumeci (Cuneo) Learn the potential role of novel functional imaging techniques Evaluate how to best implement FFR-CT and QFR

15:05 Clinical scenario and context: A case example of CT in a patient with atypical chest pain and anoumalous coronary original

Claudio Larosa (Andria)

15:10 Discussion and audience interaction

15:20 How would I treat the case? Stefano Galli (Milano)

15:25 How did I treat the case? Claudio Larosa (Andria)

15:30 Case consensus Giuseppe Musumeci (Cuneo)

15:35 Clinical scenario and context: A case example of QFR in a patient with MVD Domenico Di Girolamo (Caserta)

15:40 Discussion and audience interaction

15:50 How would I treat the case? Nicolas Van Mieghem (Rotterdam - NL)

15:55 How did I treat the case? Domenico Di Girolamo (Caserta)

16:00 Case and Session consensus Andreas Baumbach (London - UK)

ROOM RED 2

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16:10 JOINT SESSION GISE - PCR 17:20 PCR IMAGING CASE BASED FOCUS APPLIED HOW SHOULD I TREAT COMPLEX STENOSIS WITH IMAGING GUIDANCE? Chairpersons: Lorenz Räber (Bern - CH), Ferdinando Varbella (Rivoli)

16:10 Session objectives - Ferdinando Varbella (Rivoli) Update on the latest clinical evidences on imaging guidance of PCI Learn how to best adopt the available imaging techniques (IVUS, OCT, NIRS, etc.)

16:15 Clinical scenario and context: A challenging PCI of LM guided by IVUS Gioel Gabriel Secco (Alessandria)

16:20 Discussion and audience interaction

16:30 How would I treat the case? Alaide Chieffo (Milano)

16:35 How did I treat the case? Gioel Gabriel Secco (Alessandria)

16:40 Case consensus Ferdinando Varbella (Rivoli)

16:45 Clinical scenario and context: PCI in ACS patient guided by OCT Michael Joner (Munich - D)

16:50 Discussion and audience interaction

17:00 How would I treat the case? Bernardo Cortese (Milano)

17:05 How did I treat the case? Michael Joner (Munich - D)

17:10 Case and Session consensus Lorenz Räber (Bern - CH)

ROOM RED 2

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17:20 JOINT SESSION GISE - PCR 18:30 PCR IMAGING CASE BASED FOCUS APPLIED TREATMENT STRATEGIES FOR CHALLENGING CASES Chairpersons: Dariusz Dudek (Krakow - PL), Flavio Luciano Ribichini (Verona)

17:20 Session objectives - Dariusz Dudek (Krakow - PL) Learn how to integrate both physiologic and imaging tools Understand how to identify culprit lesions and optimize PCI

17:25 Clinical scenario and context: Multivessel disease patient with intermediate Syntax score Luca Favero (Treviso)

17:35 Discussion and audience interaction

17:45 Clinical scenario and context: A post-PCI case optimized by both imaging and physiology Giampaolo Niccoli (Roma)

17:55 Discussion and audience interaction

18:05 Clinical scenario and context: A case of anatomical-functional mismatch Christoph K. Naber (Zurich - CH)

18:15 Discussion and audience interaction

18:25 Session evaluation and key learnings Flavio Luciano Ribichini (Verona)

ROM RED 2

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ED. VILLAGE - CORNER F

15:00 ORAL COMMUNICATIONS 15:30 PCI Chairpersons: Salvatore Colangelo (Torino), Eugenio Stabile (Napoli)

15:30 ORAL COMMUNICATIONS 16:00 PCI AND STEMI Chairpersons: Alessandro Bellis (Napoli), Giovanni Valenti (Andria)

16:00 RIGHT HEART CATHETERIZATION: TIPS AND TRICKS17:00 Coordinator: Livio Giuliani (Chieti)

17:00 ORAL COMMUNICATIONS17:30 CORONARY INTERVENTION Chairpersons: Elisabetta Ricottini (Roma), Fabio Felice Tarantino (Forlì)

17:30 ORAL COMMUNICATIONS 18:00 COMPLICATIONS Chairpersons: Davide D’Andrea (Napoli), Luca Testa (San Donato Milanese)

18:00 ORAL COMMUNICATIONS18:30 MISCELLANEOUS Chairpersons: Bernardo Cortese (Milano), Pasquale Spadaro (Napoli)

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08:00 LIVE CASES 09:15 from UOC di Cardiologia Centro Alte Specialità e Trapianti, Azienda

Ospedaliera Policlinico Universitario V. Emanuele, Catania Coordinator: Corrado Tamburino Resident Operators: Carmelo Sgroi, Carmelo Grasso, Alessio Gaetano La Manna Chairperson: Alberto Cremonesi (Bergamo) Co-chair: Francesco Bedogni (San Donato Milanese) Webmoderator: Giuseppe Mezzapelle (Sciacca) Factoid: Magdalena Cuman (Verona) Commentators: Roberto Bonmassari (Trento), Francesco Costa (Messina),

Germano Di Sciascio (Roma), Corrado Lettieri (Mantova), Andrea Pavei (Padova), Paolo Rubino (Pomigliano D’Arco), Amerigo Stabile (Palermo)

Clinical Anatomical Correlation: Cristina Basso (Padova)

09:15 EVIDENCE-PRACTICE MISMATCH 10:45 Chairpersons: Germano Di Sciascio (Roma), Flavio Luciano Ribichini (Verona),

Fabio Felice Tarantino (Forlì)

LEFT MAIN WITH INTERMEDIATE SYNTAX SCORE

09:15 EXCEL, NOBLE and RCT Alaide Chieffo (Milano)

09:22 Presenter clinical practice vs clinical trials Eberhard Grube (Bonn - D)

09:29 Discussion

REVASCULARIZATION DRIVEN BY FUNCTIONAL ASSESSMENT

09:37 Presenter clinical trials / guidelines Flavio Luciano Ribichini (Verona)

09:44 Presenter clinical practice Massimo Fineschi (Siena)

09:51 Discussion

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MITRAL REPAIR DEGENERATIVE AND FUNCTIONAL

09:59 Presenter clinical trials / guidelines Bruno Melica (Vila Nova de Gaia - P)

10:05 Presenter clinical practice Francesco Maisano (Zurich - CH)

10:12 Discussion

DUAL VS TRIPLE ANTIPLATELET THERAPY IN AF

10:21 Presenter clinical trials / guidelines Alberto Menozzi (Parma)

10:28 Presenter clinical practice Kirk N. Garratt (Newark Delaware - USA)

10:35 Discussion Experts: Paola Colombo (Milano), Leonardo Spedicato (Udine),

Amerigo Stabile (Palermo)

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10:45 CLINICAL CASES COMPETITION AND GISE AWARDS11:30 Chairpersons: Sergio Berti (Massa), Leonardo Bolognese (Arezzo),

Marino Scherillo (Benevento)

11:30 LIVE CASES 12:50 from UOC di Cardiologia Centro Alte Specialità e Trapianti, Azienda

Ospedaliera Policlinico Universitario V. Emanuele, Catania Coordinator: Corrado Tamburino Resident Operators: Carmelo Sgroi, Carmelo Grasso, Alessio Gaetano La Manna Chairperson: Gennaro Santoro (Massa) Co-chair: Eberhard Grube (Bonn - D) Webmoderator: Davide Lanzellotti (Castelfranco Veneto) Factoid: Simone Calcagno (Roma) Commentators: Giulio Bonzani (Napoli), Paola Colombo (Milano),

Maurizio D’Urbano (Magenta), Kirk N. Garratt (Newark Delaware - USA), Bruno Melica (Vila Nova de Gaia - P), Leonardo Spedicato (Udine), Eugenio Stabile (Napoli)

Clinical Anatomical Correlation: Cristina Basso (Padova)

12:50 CLOSING REMARKS 13:00 Giovanni Esposito (Napoli), Giuseppe Tarantini (Padova)