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12/04/2013 Scientists back roadmap to rid world of polio by 2018 - SciDev.Net

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New intravenous vacc ine

w ill soon replace the oral

vaccines that countries

currently rely on

Anthea Sieveking/Wellcom

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The scientists' declaration says polio eradication isachievable within five years

It backs calls for the phasing out of an oral vaccinethat has itself caused outbreaks

The scientists also call for extra money to fund theplan's goals

NEWS

Scientists back roadmap to rid world of polio by 2018Richa Malhotra

11 April 2013 | EN

Around 400 scientists from 80 countries have come together to declare that polio

could be wiped off the face of the Earth in five years if plans to eliminate both wild and

vaccine-derived polioviruses are implemented.

In a 'Scientific Declaration on Polio Eradication', published today (11 April), eminent

scientists and public health experts emphasise the feasibility of eradicating the

disease and endorse a recent draft plan that sets out a roadmap to doing so by 2018.

The 'Polio Eradication and Endgame Strategic Plan 2013-2018' is being developed by

the Global Polio Eradication Initiative (GPEI) an international partnership of the

WHO, UNICEF, Rotary International and the US Centers for Disease Control and

Prevention. The latest version of the draft plan was published this week (9 April).

"There has been a

perception that polio is not eradicable. We develope

the declaration to underscore the science

behind [this goal] and to say that this is doable," say

Zulfiqar Bhutta, head of the Division of Women and

Child Health at the Aga Khan University in Pakistan.

He is the joint leaderofthe declaration, along with

Walter Orenstein, associate professor at the Emory

Vaccine Center in the United States.

"The declaration also calls for additional resources to eliminate the gap in funding needed for the eradication

plan," Bhutta tells SciDev.Net.

He adds that improved vaccination strategies are needed to address the polio endgame.

One of the declaration's signatories, David Heymann, chair ofPublic Health England's advisory board in the

United Kingdom, says that much remains to be done.

"GPEI has set a target of 2018 and it has been encouraged by the fact that India has now become polio-free

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7/28/2019 Scientists back roadmap to rid world of polio by 2018

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12/04/2013 Scientists back roadmap to rid world of polio by 2018 - SciDev.Net

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which was a challenge," he says. "The remaining three countries that are endemic Nigeria, Afghanistan an

Pakistan have challenges of their own."

"The main challenge is to vaccinate all the children in order to establish immunity in the communities,"

Heymann says.

There were only 250 polio cases reported from five countries last year, compared with 350,000 from 125

countries in 1988.

"The vaccine seems to have worked in most countries, so there's no reason it wouldn't work in the countries

that are left," he explains, adding that "the technology that we need to eradicate polio is there".

The GPEI plan aims to strengthen routine immunisation programmes and the surveillance of virus

transmission.

The declaration supports the plan's objective to stop using the trivalent oral polio vaccine that contains

all three types of wild polioviruses types 1, 2 and 3 in an attenuated, albeit living, state.

The continued use of wild poliovirus type 2, which was eradicated in 1999, in this vaccine has been found tobe a major cause ofvaccine-derived polio outbreaks.'

To avoid further such outbreaks, new inactivated polio vaccines (IPV), which are given intravenously, will be

introduced to the routine immunisation programmes in countries that rely on oral vaccines, according to the

plan.

Recently developed bivalent oral vaccines, lacking the type 2 poliovirus, will then replace the trivalent

vaccines.

The declaration acknowledges these steps as "strong solutions to challenges".

Sona Bari, a spokeswoman for the GPEI in Geneva, Switzerland, tells SciDev.Net the scientists' declaration is

a strong endorsement of her organisation's plan.

"Polio eradication is a global win, so we need every single country to fund and finance it as well," she says.

John L. Sever, vice- chair of the International PolioPlus Committee of Rotary International, says: "The scientif

declaration is consistent with the objectives of the strategic plan and its importance. Scientific support and

advice have been vital to the development of the strategic plan and [will be] in its implementation."

Link to the draft polio eradication strategic plan

Link to the scientific declaration

http://www.scidev.net/en/health/news/scientists-back-roadmap-to-rid-world-of-polio-by-2018.html

http://vaccines.emory.edu/poliodeclaration/text.pdfhttp://www.polioeradication.org/Portals/0/Document/Resources/StrategyWork/EndgameStratPlan_20130409_ENG.pdfhttp://www.scidev.net/en/news/vaccinederived-polio-spreads-in-nigeria.htmlhttp://www.scidev.net/en/health/infectious-diseases/news/fear-of-vaccination-last-hurdle-in-polio-eradication-1.html