In this issue: 04  |  Investigating Misfiring Marrow

Improving the options for patients

with bone marrow failure.

08  |  Training Ground

Seattle Children’s is home to one of the nation’s top training programs for pediatricians.

12  |  Passion for Prevention

Dynamic duo strive to stop drowning deaths through research, outreach and advocacy.

Connection

Spring 2010

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From Where I Stand

Rosalie FrankelArt TherapistSeattle Children's

I am a healer. I am part of the medical team. In place of a stethoscope and thermometer, my little black bag is a cart loaded with art supplies — paper, paints, pastels, pictures clipped from magazines and modeling clay. Through the language of art, I help kids bring voice to feelings they may not be able to verbalize or may not even be aware of.

Every day, I see children and teens who are dealing with physical discomfort, loss of control and loss of choice. Stressors of the hospital experience — like facing a scary procedure or not being able to play a favorite sport — can bring kids to places of anxiety, resistance, with­drawal and despondency.

I help them cope.

I meet my patients where they are emotionally and provide them with an avenue of expression while they’re confined to the hospital. The work we do together helps them engage in life and shift from feeling passive to playful.

For some children, the process provides a distraction from illness or pain — and the benefit is entirely in the moment. For others, the art creates a sense of empowerment and a stronger sense of self — these effects can last a lifetime.

For all of these children and teens, the artwork helps their care teams see them as unique individuals — not just as a patient or a diagnosis. For their families, this may be one of the most healing things of all.

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Connection Team

Jennifer Fisch Executive Editor

David Perry Vice President of Marketing and Communications

Valerie Courtney Senior Director of Development, Annual Giving and Donor Relations

Allison Broadgate Marketing and Communications Manager

Kathi Elliott Brand and Production Manager

Nate Brown Production Specialist

feature story writers Lisa Brihagen Brad Broberg

contributing writers Elizabeth Austen Lisa Brihagen Keith Mack

design

Methodologie, Seattle

cover photography Therese Frare

featured photography Nancy LeVine

photographers Arthur & AssociatesDave Conger Paul DudleyScott Eklund, Red Box PicturesDuell Fisher, Team PhotogenicVivian Hsu, Team PhotogenicAileen Kelly Eve KoppChristina LuiMichael MatisseFrank Melcher Elise Nelson

Contents

Feature Stories

04 | Investigating Misfiring Marrow We are meeting the varied medical needs of bone marrow failure patients with a range of specialized care and ongoing research to find a cure.

08 | Training Ground Seattle Children’s is home base for the Northwest region’s pediatricians­in­training — a relationship that benefits patients and families, our own physicians and the community.

12 | Passion for PreventionDr. Linda Quan and Elizabeth Bennett are preventing drowning deaths through research, outreach and advocacy.

In Every Issue

14 | What’s Happening at Seattle Children’s

18 | On the Scene

22 | Calendar of Events

23 | At a Glance

Spring 2010

“A tree is known by its fruit; a man by his deeds.”— Saint Basil

To learn more about Seattle Children’s, visit www.seattlechildrens.org. If you’d like to stop receiving Connection, please contact us at 206-987-2153 or at askus@seattlechildrens.org.

connection Vol. 12 no. 2 © 2010 Seattle Children’s, Seattle, Washington. All rights reserved.

cover Dr. Akiko Shimamura is one of many physician­scientists at Seattle Children's working to improve treatments and find cures through research.

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Bone marrow failure is considered a rare disease, but don’t try telling that to Dr. Akiko Shimamura. Since she started the Bone Marrow Failure Program at Seattle Children’s in 2007, growing numbers of patients are being referred to the program for diagnosis and treatment.

Bone marrow failure is not just one disease. It’s a group of nonmalignant but life­threatening syndromes that can be inherited or acquired. “On its own, each disorder is rare, but when you pool them all together, they’re really not so rare at all,” Shimamura says.

Every month, 16 to 20 children with congenital neutropenia, aplastic anemia or some other form of bone marrow failure come to Shimamura’s program, which is one of just a handful nationwide and the only one of its kind in the region.

Caring for children with bone marrow failure is complex. It requires a wide range of medical specialists who are able to address the many complications associated with each syndrome. Expertise with bone marrow transplants is also needed, as it’s the only known cure for patients with diseases causing bone marrow failure.

“Children’s has everything it takes to have an outstanding bone marrow failure program,” Shimamura says. “All of the expert care that patients and their families need is available here.”

It helps that Shimamura and others at Children’s are actively studying what

causes bone marrow failure and striving to improve treatment. “Because we’re constantly working to learn more, we can offer patients advanced diagnostic testing and therapies that aren’t available everywhere,” Shimamura says.

That’s the case for Jayne Johnson. The 16­year­old from Kent was diagnosed with congenital neutropenia as a toddler, putting her in constant danger of potentially fatal bacterial

Investigating Misfiring Marrow Seattle Children’s meets the varied medical needs of bone marrow failure patients with a range of specialized care and ongoing research to find a cure.

infections and requiring repeated trips to the hospital. Now, she’s looking forward to the possibility of beating the disease, thanks to a new approach to bone marrow transplant being explored by Dr. Lauri Burroughs, a bone marrow transplant expert at Children’s.

“I’m super excited about getting a transplant,” Jayne says. “If I have a good outcome, it means I won’t have neutropenia anymore.”

(Above) Dr. Akiko Shimamura studies the molecular pathways within the body's cells that lead to bone marrow failure.

(Left) Jayne Johnson, 16, is among the first generation of kids with severe chronic neutropenia to live past infancy thanks to a medicine that was newly approved when she was diagnosed in 1994.

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associated with their syndrome, which range from organ failure to leukemia to solid­tumor cancers.

Although medications and transfusions can help many children cope with bone marrow failure, severe cases can lead to fatal infections and bleeding. “Even without our help, some children do OK for a long time, but when things go bad, they really go bad,” Shimamura says. “If we see them early enough, we can manage their disease and begin treatment promptly when the chances of success are highest. If not, by the time we do see them, they often do poorly.”

Catch-22

The only known cure for bone marrow failure is a successful bone marrow transplant, but the rigorous nature of current transplant protocols often presents higher risks for these patients because of their underlying health problems.

“ By using less intense regimens, we can offer transplants sooner."

— Bone marrow transplant expert Dr. Lauri Burroughs

Too few blood cells

Bone marrow failure means the marrow inside the bones isn’t making enough of one or more of the kinds of blood cells the body needs — white blood cells to fight infection, red blood cells to carry oxygen, or platelets to make the blood clot and stop bleeding.

If the marrow fails to make enough white blood cells, children are at higher risk of infection and may get sick more often. If it makes too few red blood cells, children may tire easily and become pale and dizzy. If it makes too few platelets, children may bruise or bleed easily.

Each type of bone marrow failure involves one or more of these defects. Patients with congenital neutropenia, for example, don’t produce enough white blood cells, while those with aplastic anemia don’t produce enough of all three types of blood cells.

All children with bone marrow failure remain at risk for various complications

It’s a catch­22. “If you wait too long,” says Shimamura, “you miss the best opportunity for a successful transplant before severe medical complications or leukemias develop. But if you go too early, you risk giving a transplant to a child who may not have needed one. A significant percentage of patients will need a transplant at some point in their lifetime, but the challenge is determining who will or won’t.”

Jayne is a good example of that dilemma. Her disease has been successfully managed for a long time, but recently the daily injections she’s been taking to boost her white blood count stopped working well and starting causing debilitating side effects. “It’s really affected my quality of life because I’ve been in the hospital a lot with infections,” she says. “I also have a lot of bone pain and have to lie down a lot.”

Jayne’s ticket to health may be a potentially safer type of bone marrow transplant being explored by Burroughs, who does research at the Fred Hutchinson Cancer Research Center.

Expanding transplant options

Bone marrow transplants were originally developed to treat leukemia, a cancer of the blood. Like bone marrow failure, leukemia is a disorder

(Above) Dr. Akiko Shimamura helps Jayne Johnson manage her illness and look ahead to a brighter future.

(Left) Dr. Lauri Burroughs is working to make bone marrow transplants safer for patients with bone marrow failure and immune deficiency diseases.

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Research funding is scarce for rare diseases such as bone marrow failure,

so contributions from private donors are important to advancing treatment.

After losing their daughter, Carla, to aplastic anemia more than 40 years ago,

Jim and Marjorie Ghiglione created an endowment at Children’s to support

research aimed at preventing, treating and eliminating the disease.

“We would love to see doctors be able to detect aplastic anemia early and

head it off before it results in the catastrophic outcomes we still see today,”

says Jim Ghiglione.

Dr. Akiko Shimamura is working on just that. She is looking for the

molecular pathways within the body’s cells — including the genetic mutations

— that lead to bone marrow failure. “Once you find a pathway, you can use it

to diagnose the disease and develop therapies to stop it,” says Shimamura,

who recently published a paper about a novel molecular pathway that might

be targeted with drugs to treat Shwachman­Diamond syndrome, a rare

disease that affects the pancreas, bone marrow and bones.

Although the population of bone marrow failure patients is small,

Shimamura’s research has broad implications. “These syndromes are closely

linked to leukemia, solid tumor cancers and other diseases,” Shimamura

says, “so whatever we learn about the pathways leading to bone marrow

failure can also help us understand other pathways, such as ones leading

to breast cancer.”

Exploring Molecular Pathways

Jim and Marjorie Ghiglione

of the marrow, but instead of producing too few of one or more kinds of blood cells, it produces too many.

The standard regimens used to prepare leukemia patients for transplant rely on powerful doses of drugs and/or radiation to destroy both the cancer and the old marrow. But high doses can be difficult to tolerate, especially for the elderly and people with additional health problems, so the Hutchinson Center began developing less intense alternatives for cancer patients.

Burroughs wondered how those alternatives might work with other types of patients who would also have difficulty tolerating high doses of drugs and radiation. She is currently conducting four clinical trials for children with nonmalignant disorders, such as immune deficiency diseases and bone marrow failure. Each trial is using a regimen adapted from low­intensity protocols that were developed for leukemia patients.

The hope is that the less intense regimens will make transplants a safer option for patients with immune deficiencies and bone marrow failure.

“Often they aren’t considered for transplant until their disease is so advanced because the standard regimens are too risky, but by that time they’re so sick that the risks are even greater,” Burroughs says. “By using less intense regimens, we can offer transplants sooner, when patients are in a better position to handle them, and to patients who may have been too sick to receive the standard regimens.”

That gives people like Jayne a better shot at a brighter future. She’s looking forward to playing basketball and taking her two dogs, Taffy and Tyrone, for walks again — activities she’s had to give up because of chronic pain. “There are still risks with a transplant, but there are so many rewards,” Jayne says.

Early results from one of the low­intensity trials look promising. A group of patients with immune deficiency experienced a 90% success rate with one of the less intense regimens.

“There’s still a long way to go, but I think this could have a huge impact,” Burroughs says.

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Training GroundSeattle Children’s is home base for the Northwest region’s pediatricians­in­training

Dr. Luz Gonzalez reconnects with 5­year­old cancer survivor Keaton Wrenn — a boy she treated during her residency at Seattle Children's.

By the time Lisa Wrenn’s son, Keaton, turned 16 months, the nagging in the back of her mind was turning into an ache in the pit of her stomach.

“Keaton was still walking like he was taking his first steps,” remembers Wrenn. “I just had this bad feeling about it.”

Even though her son met all of his other developmental milestones, Wrenn pushed their pediatrician for an MRI. “I wanted more proof that Keaton’s balance issues were normal for his age,” she says.

The phone was already ringing when they arrived home from the test. A malignant tumor in Keaton’s brain had spread cancer all the way down his spine.

“They told us to go to Seattle Children’s,” recalls Wrenn. Within a day surgeons removed the tumor, but Keaton’s care team remained guarded about his chances for long­term survival.

Enter Dr. Luz Gonzalez, a first­year “resident” or pediatrician­in­training. During her six­week rotation on the

cancer unit, her job was to get to know families like the Wrenns, collect additional information for their medical histories and answer their questions.

Wrenn says Gonzalez was instru­mental in helping her understand Keaton’s diagnosis and teaching her how to navigate the hospital system.

“Dr. Luz was very up front about what she knew and what she didn’t,” explains Wrenn. “She was clearly there to master her profession, and she viewed finding answers to my questions as part of that process.”

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Gonzalez carried out her work under the supervision of senior residents and experienced physicians, who are also faculty members at the University of Washington (UW) School of Medicine. Part of their academic responsibility is to mentor and train residents.

It’s precisely this learning atmos­phere — with open discussions and the pooling of ideas from multiple physician perspectives — that results in better care for children and families.

Wrenn credits her son’s recovery to the medical curiosity of residents like Gonzalez and the seasoned clinical expertise of the faculty. Now 5, Keaton is a bright, inquisitive preschooler who will start kindergarten in the fall.

Medicine with heart

Wrenn was thankful for more than Gonzalez’s medical knowledge — she was equally grateful for her ability to relate on a human level.

“Many evenings, she stopped by to give us emotional support,” remembers Wrenn. “She often sat with me and held my hand while I lay with Keaton in his hospital bed and cried.”

Every year on the anniversary of Keaton’s diagnosis, Wrenn sends a thank­you e­mail to Gonzalez and the other clinicians who played a special role in her son’s care.

“My interactions with Dr. Luz were more meaningful than she will ever know,” reflects Wrenn. “She treated me as much as she treated Keaton.”

As for Gonzalez, she still has a birthday card that Keaton drew for her nearly four years ago. For her, it’s a reminder of the resiliency of children and a confirmation that all of her hard work at Children’s was worth it.

Cream of the crop

One of every three medical school seniors in the nation who decides to go into pediatrics applies to the UW Pediatric Residency Training Program at Seattle Children’s Hospital.

That’s more than 1,000 applicants each year.

Only 280 or so are invited to Seattle for day­long interviews. When top appli­ cants are ranked, 10 current residents and 10 faculty members have equal say — a democratic selection process that is unique among residency programs.

Ultimately, only 32 physicians are chosen for the three­year program. The average age of new residents is between 27 and 30.

The collegial relationship between chief resident Dr. Shaquita Bell and her mentors Drs. Jim Stout (left) and Ben Danielson helped her learn the ropes and keeps her teachers on their toes.

“The applicants we accept are the cream of the crop,” says Dr. Heather McPhillips, the program’s associate director and a pediatrician at UW’s Roosevelt Clinic. “They’ve done incredibly well in medical school, have extraordinary life experiences and possess great interpersonal skills.”

Educating the region’s pediatricians

UW is known for having one of the top five pediatric residency programs in the U.S., but few realize that the Children’s­based program is the only pediatric residency program in our five­state academic region — Washington,

1/3 of all medical students interested in a pediatric residency apply to Seattle Children’s.

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Current resident Dr. Daniel Mallon (far left) and Dr. Heather McPhillips (far right), the residency program's associate director, take medical students on a hospital tour. Each year, more than 1,000 applicants vie for the 32 spots in our nationally recognized program.

Wyoming, Alaska, Montana and Idaho.Although two­thirds of new residents

come from other parts of the country, many stay in the region after they graduate. Many become general pediatricians in the community. Others decide to pursue additional three­year fellowships, specializing in a particular area of pediatric medicine such as cardiology or oncology.

“The way we develop and preserve quality pediatric care here and throughout our region is by providing exceptional training to the best and brightest pediatricians,” explains program director Dr. Richard Shugerman, an emergency medicine physician at Children’s. “We make space for residents to pursue their individual goals, rather than giving them a cookie­cutter experience.”

The student makes the teacher

The one­on­one focus, rigorous training program and collegial atmosphere were an irresistible combination for chief resident Dr. Shaquita Bell, who hails from Minnesota but intends to settle and practice pediatric medicine in the Northwest.

“Children’s truly values its residents. It shows in the way we’re expected to think independently and have a voice in patient­care discussions,” remarks Bell. “Friends at other residency programs

have told me they’re treated more like order takers than decision makers.”

Faculty members agree that the opportunity to teach the next generation of pediatricians is one of the perks of practicing medicine at Children’s.

“Working with residents is one of the most valuable things I do,” says Children’s gastroenterologist

By tasting some of the most commonly prescribed antibiotics, residents get a visceral understanding of their patients' hesitancy to take medicines.

and assistant professor in the UW Department of Pediatrics Dr. Tyler Burpee, who encourages trainees to challenge his medical decisions.

“They have open minds and may consider a diagnosis I’ve discounted,” he explains. “Their idealism and energy is contagious. I learn something each time I interact with them. The residents make it impossible for me to get stale in my practice.”

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Washington communities — Port Angeles, Bellingham or Yakima — and become part of a general pediatrics practice there. Few other residency programs offer such an opportunity.

Together, the facets of the Children’s program give residents a powerful lens into the span of pediatric medicine — from common, everyday parenting concerns to the most serious and complex ailments.

These experiences also help residents set the direction for their future.

Third­year resident Dr. Aaron Grigg’s experience in Pocatello, Idaho, was a big part of the reason he thought he wanted to become a general pediatrician. After spending two months there, he was leaning toward practicing medicine in a rural community where he could help make a difference.

Dr. Aaron Grigg's residency experiences in Pocatello, Idaho, and at Mercer Island Pediatrics influenced his decision to practice in a rural Washington community when he graduates in June.

Experience to build a life on

The residency program at Children’s puts trainees “at the center of birth, death and everything in between,” says 2006 graduate Dr. Matt Kronman, who is now an infectious disease fellow at Children’s Hospital of Philadelphia.

Residents spend most of their time at Children’s immersed in emergency, intensive care, cancer and general hospital medicine. The remaining time in Seattle is focused on newborn care at UW Medical Center, pediatric trauma and burns at Harborview Medical Center and general pediatrics in several community clinic settings.

A hallmark of the program, known as the “rural practice experience,” gives trainees a unique perspective on what it’s like to practice medicine away from the resources of a major hospital. Residents live for two full months in Pocatello, Idaho, or one of three

Grigg’s experience at Mercer Island Pediatrics — where he spends half a day each week — sealed the deal. While working with pediatrician and mentor Dr. John Schreuder, he decided his true calling was “being involved in all aspects of a patient’s life.”

When Grigg graduates in June, he’ll start his career as a community pediatrician at the Yakima Valley Farm Workers Clinic in Toppenish, Wash.

Full circle

Once during his residency, Kronman attended the “terminal birth” of a child with a fatal kidney condition. In the span of a few minutes, he pronounced the baby’s time of birth and time of death.

“Children’s residency program is a series of these defining moments and unforgettable experiences — unlike anything I’ve experienced before or since,” he says.

It’s been four years since he graduated, and Kronman pays honor to the faculty who mentored him.

“They modeled the true meaning of humanity for me by being wonderful physicians and wonderful people who recognized the need for balance. They taught me that I can be a fantastic person and a fantastic doctor at the same time.”

“ My mentors taught me that I can be a fantastic person and a fantastic doctor at the same time.”

— Dr. Matt Kronman, 2006 residency program graduate

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Passion for Prevention Dynamic duo strive to stop drowning deaths through research, outreach and advocacy.

Dr. Linda Quan and Elizabeth Bennett share a mission and a passion. For nearly 20 years, they’ve studied what leads to children drowning and used what they’ve learned to prevent drowning deaths.

Drowning is second only to car crashes as a cause of injury death among children ages 1 to 14, but few were exploring the reasons and looking for answers to open­water drowning (those that don’t involve pools, boats or bathtubs) — before Quan and Bennett dove in.

“We’re passionate about this work because drowning deaths are so preventable,” Quan says. “We see families torn apart by guilt and depression because they look back and see how simple it may have been to avoid a tragedy.”

Wearing a life jacket, swimming in areas with lifeguards, learning to swim and keeping a constant eye on young children could prevent many drownings, yet drowning still claims an average of 25 children under the age of 20 in Washington every year. And while the state’s drowning rates have declined over the last 20 years, they remain higher than national rates.

“I hate watching the news on the first warm days of spring because someone — often a teen — will drown because they overestimated their ability or underestimated the risks such as cold water and swift currents,” Bennett says.

Driven by research

Quan, an emergency medicine doctor at Seattle Children’s, first became interested in drowning when she was a resident at Harborview Medical Center. A 3­year­old girl who fell into an apartment pool was brought to the emergency department after being revived at the scene. Quan wondered two things: how did the girl survive, and why did she fall into the pool in the first place?

Her curiosity — and the lack of details being collected about drowning incidents — led her to create a drowning database for King County so she could investigate underlying factors such as age, location and supervision. Quan later led studies on drowning in all age groups that quantified many of the risks. These studies showed, for example, that preschool­age children were most likely to drown in swimming pools, teens were more likely to drown in lakes or rivers, and that drowning rates for Asian­Americans were double that for whites.

Insights from these studies — along with the stories of each child or teen who drowns — drive everything Quan and Bennett do. “The reasons a 4­year­old drowns are different than the reasons a 14­year­old drowns,” says Bennett, director of Guest Services, Partnerships and Advocacy

Swimming pools are where water safety starts, say open­water drowning prevention experts Dr. Linda Quan and Elizabeth "Tizzy" Bennett, because they're where people learn how to swim and be safe in other water environments.

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Unintentional drowning rates per 100,000 by age group, 3-year rolling averages, Washington state residents

at Children’s. “You have to tailor your message according to the developmental level as well as the knowledge, beliefs and behaviors of each group.”

That’s a constant challenge, but Quan and Bennett remain driven by conviction. “Why should even one child drown?” Bennett asks. “Prevention is the key.”

Focus on open water

Quan’s and Bennett’s work has made them — and Children’s — internationally recognized as leaders in drowning prevention and inspired a special focus on open water such as lakes and rivers.

Drowning as a result of playing in or on open water is a particular threat in Washington state and other places that have easy access to open water — especially among teenagers and young adults. The Centers for Disease Control recently awarded Seattle Children’s a grant to partner with the state Department of Health and create open­water drowning prevention policies for the state. Quan and Bennett are also co­chairing an international task force that is

developing open­water drowning prevention messages for use worldwide.

“People aren’t looking to get themselves into trouble when they’re playing in the water,” Bennett says. “They want to be safe, but they often lack the skills, the resources like life jackets, access to lifeguarded beaches or the knowledge of water risks and safety. Linda and I feel a responsibility to do something about that.”

Quan and Bennett have approached drowning prevention from a variety of angles. They’ve studied how to promote water­safe behaviors among diverse communities and age groups such as teenagers, helped pass a state law requiring children younger than 13 to wear life jackets in small boats and are constantly assisting local, national and international organizations such as the American Red Cross, Army Corps of Engineers and National Park Service with their drowning prevention strategies.

“I know we are making a difference because people keep asking us for help,” Quan says. “We put open­water drowning on the radar in the U.S. and there’s really nobody else doing that.”

“ I hate watching the news on the first warm days of spring because someone — often a teen — will drown.”

— Elizabeth Bennett, drowning prevention expert

When research showed that teens are more likely to drown in open water, Dr. Linda Quan and Elizabeth Bennett developed programs — like a life­jacket fashion show — to mitigate that risk.

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Zimmerman Receives Distinguished Career Award

Growth and Capacity. These two words have been top of mind at Seattle Children’s for several years.

As you may know, we have struggled with capacity issues and need to grow so we can meet current and future demand for our services. Last year alone, we diverted nearly 80 patients to other facilities because we didn’t have enough space at our Seattle hospital.

We are happy to report that on April 5, the Seattle City Council approved our Major Institution Master Plan to expand our main hospital campus in four phases over 20 or more years. Those of you who have been following this issue know it’s been a long journey, and we’ve hit a few bumps along the way.

We appreciate the work of the Citizens Advisory Committee who

helped us develop a plan that works for the hospital and the northeast Seattle neighborhoods.

A recent turning point came in early February when Seattle Children’s and the Laurelhurst Community Club reached an agreement about the hospital’s proposed expansion. In March, the agreement was jointly presented to the city’s Committee on the Built Environment, thus paving the way for its recommendation for full council approval.

There are more steps to complete before we put our shovels in the dirt, but we are grateful today that we are able to continue moving forward. We are also grateful for the steadfast support from friends and neighbors like you in our ongoing efforts to provide world­class pediatric care to all the children in our region who need us.

What’s Happening at Seattle Children’s

Thank You for Supporting Our Growth

Thomas N. Hansen, MD CEO, Seattle Children’s

Cilla Joondeph Chairman, Seattle Children’s Hospital Board of Trustees

Dr. Jerry Zimmerman received the prestigious Distinguished Career Award from the American Academy of Pediatrics’ Section on Critical Care Medicine.

Jerry Zimmerman, MD, PhD, received the Distinguished Career Award from the American Academy of Pediatrics’ Section on Critical Care Medicine at the national meeting in Washington, D.C., on Oct. 17, 2009. This lifetime career award honors a pediatric intensivist who has made significant contributions to the field of pediatric critical care.

Zimmerman was among the first group of physicians to be board

certified in this field. He is known for bringing a biochemistry approach to the practice of pediatric critical care medicine, and is co­author of Pediatric Critical Care, one of the premier medical school textbooks on the topic. Zimmerman leads Seattle Children’s Division of Critical Care Medicine and is professor of pediatrics at the University of Washington.

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Seattle Children’s new Bellevue Clinic and Surgery Center opens July 20. The 75,000­square­foot “built green” facility will provide pediatric­ and adolescent–focused services not previously available on the east side.

In addition to more than 15 pediatric subspecialties, the Bellevue Clinic and Surgery Center will offer outpatient

surgical procedures, urgent care provided by board­certified pediatric emergency physicians, imaging services including MRI, ultrasound and fluoroscopy, and a sports therapy gym. The facility also includes a pharmacy and lab.

The building’s design incorporates sustainable strategies to create a warm

and welcoming healing environment while being energy efficient. Puget Sound Energy has identified $500,000 in rebate grants that Children’s is eligible for, in addition to expected savings of more than $117,000/year in energy costs.

Bellevue Clinic and Surgery Center to Open in July

Seattle Children’s awarded the 2009 W.J. Pennington Award to Washington Dental Service and the Washington Dental Service Foundation for their commitment to improving the oral health of young children in Washington state.

Together, these organizations made a $5 million gift to launch the Early Childhood Oral Health (ECOH) Program. It was the largest gift Children’s and the University of Washington (UW) had ever received to support dental care.

Children’s and the UW School of Dentistry joined forces to create a new state­of­the­art facility and program, which will be located in Seattle’s Magnuson Park and combine clinical, research and professional training activities.

Dental decay is considered the number one unmet health need and causes more than 50 million missed school hours each year. It is the most common chronic childhood disease — and it is almost entirely preventable.

ECOH will focus on early intervention and preventive dental care for children from birth to age 3. The facility, scheduled to open in summer 2010, can accommodate 40,000 patient visits annually.

The Pennington Award, named for former Seattle Times president W.J. “Jerry” Pennington, is the highest honor given by Children’s. Pennington was a respected member of the Children’s Hospital Advisory Board and a tireless advocate of the hospital’s mission.

Oral Health Catalysts Receive Pennington Award 

WDS and WDS Foundation honored for their commitment to improving dental health for young children.

This architectural rendering shows Seattle Children's new Bellevue Clinic and Surgery Center. Opening in July 2010, the center will enable Seattle Children's to bring outpatient surgery, urgent care and pediatric radiology services to the east side.

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Rottsolk Honored for Patient Advocacy

Seattle Children’s surgeons Drs. Robert Sawin and John Meehan Jr. performed the first­ever Puestow procedure using the da Vinci robot.

The complex surgical procedure is used to treat chronic inflammation of the pancreas by creating an artificial passage connecting the pancreas to the middle section of the small intestine.

“This procedure involves a lot of suturing and is a dramatic demonstration of how versatile the technology is,” says Sawin, who is surgeon­in­chief at Children’s.

They presented their results as a video conference for the American College of Surgeons and at the Minimally Invasive Robotics Association’s annual conference in late January 2010.

Surgeons Perform First Ever Puestow Procedure Robotically

Drs. John Meehan Jr. and Robert Sawin with Seattle Children’s new da Vinci robot, model “Si.” Si's 3­D visual display provides up to 10 times magnification enabling surgeons to see better than they can during traditional surgery, even when using magnifying glasses.

Åsa Rottsolk, RN, is a passionate advocate for children and teens with chronic and end­stage renal failure. Her efforts make it possible for kids like Kodey Weir (receiving dialysis) to attend Camp Orkila on Orcas Island with healthy peers.

Seattle Children’s nurse Åsa Rottsolk received the March of Dimes Nurse of the Year – Advocacy for Patients Award, in recognition of her efforts on behalf of pediatric dialysis patients.

Since her graduation as a nurse in Sweden more than 30 years ago, Rottsolk’s professional life has been devoted to nephrology and dialysis. She is passionate about raising awareness of the particular challenges faced by children and teens with chronic and end­stage renal failure.

“Sometimes it seems that they don’t receive the same attention in the wider community as kids with cancer, for example, so it’s important that someone who understands their condition advocates for their needs,” says Rottsolk.

While providing care in the Dialysis Unit, Rottsolk noticed that children and teens had very little to keep them entertained while sitting through their long treatments, typically three to four hours as many as four times each week. There was just one computer, designated for school use, and a limited video

library. She initiated a campaign to gather unused DVDs and videos. The result? An extensive collection of movies suitable for all age groups, and an additional laptop.

Rottsolk has also led efforts to fund “camperships” — scholarships to allow kids with chronic renal failure to attend one week at the YMCA Camp Orkila

on Orcas Island. After camp, she makes each child a photo CD of them and their new friends.

Rottsolk says she is grateful to be part of the highly skilled, dedicated and compassionate nephrology team at Children’s.

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Champion Tomorrow’s Care and Cures New membership program supports innovative research.

Research is at the heart of Seattle Children’s mission to prevent, treat and eliminate pediatric disease. Investigators at Seattle Children’s Research Institute are discovering innovative ways to treat and prevent conditions that negatively affect the health and well­being of children.

Our research institute is growing in funding, prestige and capacity to perform the research that will advance pediatric medicine. We are currently fifth among pediatric hospitals in funding from the National Institutes of Health, and our campus in downtown Seattle will ultimately have nearly 2 million square feet of research space.

We recently began a program called Research Champions to recognize the generosity of those who provide philanthropic support for our research efforts. Individuals who donate $1,000 or more in a calendar year can become a Research Champion, as can organizations that make gifts or grants of $2,500 or more. Members may direct their gifts toward the research institute’s greatest needs, or earmark donations for specific areas of research.

“Becoming a Research Champion shows you believe in the promise of

pediatric research,” says James Hendricks, PhD, president of Seattle Children’s Research Institute.

BNBuilders of Seattle is the lead sponsor of the new program. “We are excited to help one of the top research centers in the country reach for its goal to eliminate childhood diseases,” says Brad Bastian, company co­founder and president.

Benefits of Research Champions membership include:

• Invitation to an annual open house at Seattle Children’s Research Institute

• Presentations by Children’s scientists and a guided tour of the institute

• Participation in Research Roundtables, informal conversations with researchers about ongoing projects

• An annual research progress report

• Recognition on the Research Champions Member Wall

To learn more about Research Champions, contact Brenda Majercin at 206­987­4979 or brenda.majercin@seattlechildrens.org.

Research Champions will support the efforts of Seattle Children’s Research Institute to create a happier, healthier future for all children.

“Research Champions will help us take key initiatives to the next level.”

— James Hendricks, PhD, president of Seattle Children’s Research Institute

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On the Scene

Radiothon Rocks Remembering Dick Friel

The ninth annual Jackie and Bender’s One Big KISS for Seattle Children’s Hospital Radiothon raised nearly $937,000 for Seattle Children’s Feb. 24 and 25. Broadcast live from the hospital on 106.1 KISS FM, the program featured inspiring stories from hospital patients, caregivers and volunteers. Callers pledged almost $100,000 in the final 90 minutes of the 26­hour broadcast. “Even though money is tight, our

listeners have once again stepped up and amazed us with their generosity and compassion,” says Bender, KISS Morning Show co­host. Radiothon proceeds benefited Children’s greatest needs, meaning the hospital may use the funds to meet any of its most urgent priorities. The Radiothon is presented by the John L. Scott Foundation.

Seattle Children’s lost a dear friend when longtime charity auctioneer Dick Friel passed away Jan. 14 at age 76. For more than 30 years, Friel and his wife Sharon conducted auctions at countless hospital fundraisers, including Children’s Golf Classic, the Auction of Washington Wines and the Season of Light. Together, the couple helped raise tens of millions of dollars for Children’s.

“They were the Fred Astaire and Ginger Rogers of auctions,” says Doug Picha, president of Seattle Children’s Hospital Foundation.

Friel also conducted auctions for organizations such as the Cystic Fibrosis Foundation, PONCHO and the Fred Hutchinson Cancer Research Center. “Our community is a better place because of Dick Friel,” says Picha. “He will be sorely missed but never forgotten.”

Community support helps Seattle Children’s provide uncompensated care to patients whose families cannot afford all or part of their care. Children’s expects to provide more than $100 million in uncompensated care in fiscal year 2010.

Dick Friel, who passed away in January, conducted many auctions for local charities, including Seattle Children’s. Known for his humor and passion, Friel often began an auction with, “Ladies and gentlemen, start your wallets!”

Radio personalities Jackie (background) and Bender interview Seattle Children’s patient Alexis Douglas and her mom Jill Douglas during Jackie and Bender’s One Big KISS for Seattle Children’s Hospital Radiothon in February.

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Supporters were on hand to see the Team Seattle Guild compete on behalf of Seattle Children’s at the Rolex 24 Hours at Daytona auto race in January.

Participants and entertainers celebrated after the Run of Hope last October.

Dr. Forrest L. Flashman Guild members (from left) Jean Wedenig, Elna Duffield, Linda Crothers and Robbi DeVries helped present the 31st annual Festival of Trees to benefit uncompensated care at Seattle Children’s.

The Dr. Forrest L. Flashman Guild raised nearly $200,000 at the 31st annual Festival of Trees, held at the Fairmont Olympic Hotel in Seattle Nov. 22. Attendees viewed 20 Christmas trees created by guild members and sold to benefit uncompensated care. Each tree was dedicated to a Seattle Children’s patient. Raya Nuxoll, who underwent brain surgery at Children’s in November 2008, performed the ceremonial lighting of the Grand Tree in the hotel lobby. Guests visited the Teddy Bear Suite, enjoyed holiday entertainment by the St. Jude Choir, listened to Christmas stories and had photos taken with Santa.

Festival of Trees Welcomes Holidays

The Team Seattle Guild raised nearly $400,000 for cardiac intensive care at the Rolex 24 Hours at Daytona auto race, held Jan. 30 and 31 in Daytona, Fla. Drivers of the two Mazda RX­8 race cars included guild founder Don Kitch Jr., James Gue, Leh Keen and Dave Lacey of Team Seattle and actor Patrick Dempsey, Joe Foster and Charles Espenlaub of Dempsey Racing. It was the 13th time in 14 years the guild has competed at Daytona on behalf of the hospital. In 2009, the guild raced for Children’s at the 24 Hours of Le Mans in France.

Seattle Children’s Pediatric Brain Tumor Research Guild raised more than $253,000 through the Run of Hope, held at Seward Park in Seattle Oct. 18. Proceeds benefited the pediatric brain tumor research led by Dr. Jim Olson of Seattle Children’s. Following a 5K run and 3K walk, more than 1,000 participants enjoyed a celebration featuring games, food, prizes and live music by American Standard. The top fundraising adult won a trip for two to Kona, Hawaii. Many thanks to the Four Seasons Seattle for its generous sponsorship.

“Symphony of the Superhero,” the Symphony Guild’s 12th annual concert to benefit uncompensated care at Seattle Children’s, raised more than $150,000 at Benaroya Hall in Seattle Nov. 6. Attended by more than 2,300 guests, the symphony explored our fascination with superheroes and honored those who show courage in the face of peril, especially Children’s patients. Composer and guild founder Mateo Messina wrote and narrated the symphony. More than 280 performers participated, including DJ Cut Chemist, Lili Haydn, Natalie Dungey, the North­west Symphony Orchestra, a Brazilian band, four choirs and a bell choir.

Team Seattle Returns  to Daytona 

Running for  Research 

“Heroic” Effort for Symphony Guild

Composer and guild founder Mateo Messina chatted with Seattle Children’s patient Rishi Nair before Rishi performed a song about his experience at the hospital at the Symphony Guild concert in November 2009.

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Speaking at the sixth annual Seattle Snow Ball, former Seattle Mariner Dan Wilson encouraged guests to make a difference in the community.

Former University of Washington quarterback Marques Tuiasosopo (left) and former NFL great Warren Moon (right) congratulate current UW quarterback Jake Locker on winning a 2010 Sports Star of the Year award.

Seattle Children’s patient Taylor Sealy visits with Seattle Seahawk Will Herring and Starlight Children’s Foundation Executive Director Steve McGraw.

Seattle Snow Ball Raises $180,000

The sixth annual Seattle Snow Ball raised $180,000 for uncompensated care at Seattle Children’s. Presented by the Jack & Colleen Ryan Guild, the black­tie holiday­themed dinner and dance attracted 350 guests to the Fairmont Olympic Hotel in Seattle Dec. 20. The program included former Seattle Mariners catcher and longtime

Children’s supporter Dan Wilson. A multigenerational event, the Snow Ball invites young adults to attend with their parents and grandparents as a way of helping shape the next generation of philanthropists. Many thanks to Platinum sponsors Joe Clark, Jim and Gaye Pigott and Trilogy Equity Partners.

The 75th annual Sports Star of the Year awards show at Benaroya Hall in Seattle Jan. 19 benefited Seattle Children’s and the Seattle Sports Commission. Presented by MTR Western, the event honored the athletic and philanthropic achievements of local players and coaches. Lenny Wilkens, the winningest coach in NBA history and current Seattle Children’s Foundation trustee,

presented the inaugural Youth Sports Star award to Shawn Berg, 15. Shawn is a four­time state wrestling champion and Children’s patient who lost his sight to cancer at age 4. Seattle sports greats Steve Largent and Edgar Martinez presented the Sports Citizen award to former Seattle Mariner Jamie Moyer for his work through The Moyer Foundation.

Awards Show Benefits Seattle Children's

The Seattle Seahawks and the Starlight Children’s Foundation teamed up during the 2009 holidays to donate five Fun Center mobile video game carts to Seattle Children’s. The game carts, along with individual gifts for delighted patients and their siblings, were delivered to the hospital by Seahawks players and the Seattle Seagals Dec. 8. Many thanks to our visitors for creating unforgettable holiday memories for patients and families.

Seahawks Spread  Holiday Cheer

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Bar Mitzvah Donations to Hospital Top $15,000 

Ryan Ottinger, 13, requested donations to Seattle Children’s in lieu of presents to mark his bar mitzvah, an occasion that signified his becoming a Jewish adult. “I wanted a mitzvah project that could help save lives,” says Ryan. “I decided that raising money for Children’s was perfect. I spoke about Children’s at my bar mitzvah service because it was important for people to hear that giving to the hospital really makes a difference.” Ryan’s friends and family responded generously. If you would like to celebrate a special occasion by giving to Children’s, contact Commemorative Giving at 206­987­4844.

Holiday Promotion Supports Hospital

“Miracle Season”  Raises $140,000 

The 15th annual “Miracle Season” holiday special aired Dec. 12 on KOMO 4 and raised more than $140,000 for uncompensated care at Seattle Children’s. The parents of patients Cole Cameron and Marques Mar spoke about their experiences at Children’s, while hosts Steve Pool and Molly Shen encouraged viewers to pledge financial support. A special segment highlighted Children’s Science Adventure Lab, the only mobile science education lab in the country operated by a pediatric hospital. The Northwest Girlchoir performed holiday favorites. Thanks to sponsors KOMO 4, The Westin Seattle, Credit Unions for Kids, Log A Load For Kids and Purchase a Miracle.

Grateful Parents Give Back 60 Years Later 

When Lynn McKnight was 4, his parents Lyle and Joy McKnight rushed him to Seattle Children’s after he developed a life­threatening fever. After three weeks, Lynn recovered from meningitis. The McKnights were astounded they had to pay so little and were grateful that Children’s uncompensated care program covered most of the cost of Lynn’s care. “We thought if we ever got the money, we should give something back,” says Joy McKnight. To express appreciation, the couple recently established a charitable gift annuity that benefits uncompensated care, and provides them with guaranteed payments and tax savings. To learn about charitable gift annuities and other ways to include Children’s in your estate plans, call Lorraine del Prado at 206­987­4977 or Christina Lui at 206­987­6812.

Ryan Ottinger presents gifts to Alison Garrison, volunteer coordinator at Seattle Children’s.Ryan’s mitzvah project in support of Children’s raised more than $15,000 in donations from just over 130 friends and family members.

Shopper photos at last year’s Wonderland Nutcracker booth benefited Seattle Children’s.

Seattle Children’s patient Cole Cameron appeared on the 2009 “Miracle Season” program.

Decades after their son received uncompensated care at Seattle Children’s, Joy and Lyle McKnight established a charitable gift annuity to benefit the hospital.

The Westin Seattle and Pacific Place created a special holiday shopping and lodging promotion that raised $12,150 for uncompensated care in 2009. When customers booked a stay at the Westin, they received a gift card to Pacific

Place, and the hotel made a donation to Seattle Children’s. In addition, a portion of the proceeds from the Wonderland Nutcracker photo booth at Pacific Place benefited the hospital.

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Purchase a Miracle Days

May 1 to June 15;grocery and drug stores across Washington

Support Seattle Children’s in three ways: select products with Purchase a Miracle shelf tags, such as Newman’s Own and Coca­Cola; purchase items at PCC Natural Markets with the Kid Picks label; or buy a $1 Miracle Balloon at Haggen & TOP Food stores (June 2 to 15 only). Call 206-987-4903.

Fourth Annual Art à la Carte

Friday, May 7, 11 a.m. to 2 p.m.; The Golf Club at Newcastle

The Preston Kuppe Guild presents a luncheon with silent and live auctions featuring ceramics, paintings, photography, jewelry, textiles and metal art. $50 per person. Call 206-910-7200.

26th Annual “Miracle Makers”

Friday, June 4, 7 to 11 p.m.on KOMO 4 TV

Call during the broadcast and pledge your financial support as Seattle Children’s patients, volunteers and special guests share stories about the hospital. Co­sponsored by Costco Wholesale and KOMO 4 TV.

Children’s Ride Weekend

Gala & AuctionFriday, June 25, 6 p.m.; Fremont Studios, Seattle

Enjoy dinner, entertainment, silent auction and live auction of three custom motorcycles. $150 per person. Visit www.childrens-ride.com. Presented by the Imagine Guild.

Children’s Ride 15Saturday, June 26, 7 a.m.; register at BMC Select, Issaquah

$60 per person includes a Washington State Patrol–escorted ride, barbecue lunch, music and games. Visit www.childrens-ride.com. Presented by the Imagine Guild.

Revelry on Red Mountain

Saturday, June 26, 6 to 9:30 p.m.; Col Solare Winery, Benton City

Enjoy distinctive wines while savoring dishes prepared by chef Frank Magana of Picazo 7Seventeen and guest chef John Sarich of Chateau Ste. Michelle. $95 per person. Tickets available online May 12. Visit www.auctionofwashingtonwines.org.

22nd Annual Pacific Northwest Historics Vintage Auto Races

Friday, July 2, to Sunday, July 4, gates open at 8:30 a.m.; Pacific Raceways, Kent

More than 275 rare and beautifully restored cars will race. Adults: $25 per day or $40 for three days. Children: $5 per day. Visit www.northwesthistorics.com. Presented by the SOVREN Guild.

Woodinville Winemaker’s Triathlon/After Party

Wednesday, July 21, 6 p.m.; Willows Lodge, Woodinville

Watch winery teams compete as you sample Woodinville wines. Afterward, celebrate with winemakers for $125 per person. Proceeds benefit mitochondrial research. Visit www.nwmito-research.org.

Lenny Wilkens Celebrity Golf Classic Weekend

Dinner & AuctionFriday, Aug. 6, 5 p.m.; Bellevue Hyatt Regency

$175 per person. Tables of 10 for $1,600. Visit www.lennywilkensfoundation.org.

Golf ClassicSaturday, Aug. 7, 10 a.m.; Echo Falls Country Club, Snohomish

Golf with sports celebrities. Packages start at $275 per person. Visit www.lennywilkensfoundation.org. 

11th Annual Children’s Golf Classic Dinner Party

Sunday, Aug. 15, 4 p.m.; Safeco Field, Seattle

Attend Seattle Children’s leading fundraising event. Seating is limited. $250 per person. Visit www.friendsofcostco.org. Presented by the Friends of Costco Guild.

Auction of Washington Wines Weekend

Picnic with the Winemakers &  Barrel Auction Thursday, Aug. 19, 4 p.m.; Chateau Ste. Michelle, Woodinville

Enjoy wine tastings, a gourmet picnic, games, entertainmentand barrel and silent auctions. $125 per person until July 16; $150 thereafter. Visit www.auctionofwashingtonwines.org.

Winemaker DinnersFriday, Aug. 20; wineries and private residences in Greater Seattle

Washington winemakers and chefs will present a memorable dinner for $250 per person. Visit www.auctionofwashingtonwines.org.

Covey Run 10K & 5K Walk/Run & Kids DashSaturday, Aug. 21, 8 a.m.; start and finish at Redhook Brewery in Woodinville

Preregister for $30 or register on race day for $35. Bring pledges and donations for uncompensated care. Visit www.runforchildrens.org. Presented by the Run for Children’s Guild.

23rd Annual Gala & Auction Saturday, Aug. 21, 4:30 p.m.; Chateau Ste. Michelle, Woodinville

Black­tie gala will feature a multicourse dinner coupled with Washington wines. Live and silent auctions will feature rare wine and unique wine vacations. $500 per person. Visit www.auctionofwashingtonwines.org.

Eighth Annual Cure for Mito Auction & Dinner

Saturday, Sept. 11, 5:30 p.m.; Willows Lodge, Woodinville

Enjoy champagne and hors d’oeuvres, wine, four­course dinner, live auction and dancing. $125 per person. Visit www.nwmito-research.org. Presented by the Mitochondrial Research Guild.

Eighth Annual Kirkland Concours d’Elegance

Sunday, Sept. 12, 9 a.m. to 4 p.m.; Carillon Point, Kirkland

View rare automobiles, sidecar motorcycles and vintage boats. Adults, $25; children 7­17, $10; kids under 7, free. Visit www.kirklandconcours.com. Supported by the SOVREN Guild.

Calendar of Events

23

Boards of Trustees 2009–2010

Hospital

Cilla Joondeph

Chairman

Foundation

Peter Shimer 

Chairman

Guild Association

Laurie Boehme 

Chairman

Executive Staff

Thomas Hansen, MD

CEO

Dean Allen

Rhoda Altom

Libby Armintrout

Robb Bakemeier

Joel Benoliel

Jane Blair

Pat Char

Nancy Daly

Michael Delman

David Fisher, MD

Bob Flowers

Mary Ann Flynn

Thomas Hansen, MD

Genie Higgins

Judy Holder

Cynthia Huffman

Jim Ladd

Cindy Masin

Susan Mask

Resa Moore

Jeff Nitta

Gloria Northcroft

Laurie Oki

Rob Roskin, MD

Nancy Senseney

Jan Sinegal

Charles Stevens

Peggy Walton

Sherry Benaroya

Laurie Boehme

Cindy Brettler

Robert Cline

A.M. Clise

Ronald Crockett

Richard DiCerchio

David Fisher, MD

Shalisan Foster

Thomas Hansen, MD

Ray Heacox

Kandace Holley

Craig Jelinek

Ted Johnson

Cilla Joondeph

Craig Kinzer

Tod Leiweke

Howard Lincoln

Candy Marshall

John Meisenbach

Cameron Myhrvold

Laurie Oki

Gordon Perkin, MD

Douglas Picha

Scott Redman

Tami Reller

Fariba Ronnasi

Robert Sawin, MD

Kenneth Schubert Jr.

Jan Sinegal

Michele Smith

Dale Sperling

F. Bruder Stapleton, MD

Kelly Wallace

Robert Watt

Lenny Wilkens

Maureen Atkins

Sue Byers

Kerri Coyle

Jana Dukelow

Mary Jo Foseid

Shalisan Foster

Jennifer Goldberg

Dorothy Greenwood

Mary Lynn Holman

Jane Humphries

Mari Juntunen

Jolene Logue

Alex Lytle

Linda Maki

Louisa Malatos

Barbara Mann

Lorene Martin

Suzanne Sinegal McGill

Trish Oury

Nancy Schenck

Michele Smith

Laurie Taylor

Dixie Wilson

Jennifer Zinda

Patrick Hagan President and Chief Operating Officer, Seattle Children’s Hospital

James Hendricks, PhD President, Seattle Children’s Research Institute

Douglas Picha President, Seattle Children’s Hospital Foundation

Lisa Brandenburg Senior Vice President Chief Administrative Officer

Drexel DeFord Senior Vice President Chief Information Officer

Mark Del Beccaro, MD Pediatrician­in­Chief Chief Medical Information Officer

David Fisher, MD Senior Vice President Medical Director

Susan Heath, RN, MN Senior Vice President Chief Nursing Officer

Sanford Melzer, MD Senior Vice President Strategic Planning

Robert Sawin, MD Surgeon­in­Chief President, CUMG

Jeffrey Sconyers Senior Vice President General Counsel

F. Bruder Stapleton, MD Senior Vice President Chief Academic Officer

Kelly Wallace Senior Vice President Chief Financial Officer

At a Glance

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PO Box 5371

Seattle, WA 98145­5005

www.seattlechildrens.org

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Job#: CHILD 5783 Job Title: Research Majesky Publication/s: Connections Magazine Date: 2/17/10 Proof: 1Trim: 8.5"w x 8"h Live: n/a Bleed: 8.75"w x 8.125"h (top only) Color: CMYK Laser%: 100% Images: HiRes File Author: TH

Dr. Majesky is transforming stem cells into hope.

Renowned researcher Dr. Mark Majesky is now at Seattle

Children’s Research Institute, working with stem cells to

develop lifesaving treatments that could someday replace

invasive surgeries and transplants in children. His titles are

impressive—Director of Myocardial Regeneration Initiative

at the Center for Tissue and Cell Sciences at the

Research Institute, and Professor of Pediatrics at

the University of Washington. His work is even

more impressive. “It’s not very often that you see this level of

commitment, energy and resources from donors, a research

institute and a hospital,” says Dr. Majesky. “The Institute is a

rich, collaborative environment where researchers work

together across benches to find cures.” To learn more, visit

seattlechildrens.org/research.

Cure.

CHILD 5783 ResearchMajesky_C.indd 1 2/26/10 2:09 PM