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Second Generation, Fully Networked Smart Medical Vest UtopiaCompression UtopiaCompression Corporation Dr. Jacob Yadegar (UC) Dr. Anurag Ganguli (UC) Mr. Zvi Topol (UC) Dr. Hieu Nguyen (UC) Dr. Shalon Zeferjahn (UC) Professor William Kaiser (UCLA) Dr. Massoud Agahi (Cedars-Sinai Medical Center ) Acknowledgment Department of Homeland Security

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Page 1: Second Generation, Fully Networked Smart Medical Vest ... · Second Generation, Fully Networked Smart Medical Vest. Agenda. UtopiaCompression Slide 3. 1 – System Overview. 2 –

Second Generation, Fully Networked Smart Medical Vest

UtopiaCompression

UtopiaCompression CorporationDr. Jacob Yadegar (UC) Dr. Anurag Ganguli (UC) Mr. Zvi Topol (UC)

Dr. Hieu Nguyen (UC) Dr. Shalon Zeferjahn (UC)

Professor William Kaiser (UCLA) Dr. Massoud Agahi (Cedars-Sinai Medical Center )

Acknowledgment

Department of Homeland Security

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Second Generation, Fully Networked Smart Medical Vest

UtopiaCompression Slide 2

Develop a Fully Networked Smart Medical Vest for Health Status Monitoring of First Responders

Project Objective

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Second Generation, Fully Networked Smart Medical Vest

Agenda

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1 – System Overview2 – Sensor Suite3 – Energy Management4 – Intelligent Hierarchical Decision Support System5 – Personalization and Activity Awareness6 – Conclusions

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Two Tier Research and Development StrategyTier 1 – The Simulator

Physiological Data Warehouse Hierarchical Decision Support System

Tier 2 – The Global Integrated End-to-End System

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PDA attached to the belt

Wearable Wireless Physiological and Anatomic Sensors

Second Generation, Fully Networked Smart Medical Vest

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Second Generation, Fully Networked Smart Medical Vest

The Simulator

Data Warehouse

Communication Module

Data Storage Module

HDSS

Communication Module

Decision Tree ModulePhysiological Parsing

Algorithm

Health Status

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Second Generation, Fully Networked Smart Medical Vest

The Global System – the vision

Sensors

ECG

Body Motion

PulseOximeter

Personal Server

Peer PDA

Blue Tooth Personal Server

PDA

Personal Server

Peer PDA

Personal Server

Peer PDA Personal Server

Peer PDA

Command CenterLaptop

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BodyTemperature

CerebralOximeter

Etc.

Energy Mgmt

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Second Generation, Fully Networked Smart Medical Vest

The Sensor Suite

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Blood Pressure/Heart Rate/Heart Rhythm Irregularity (A&D MEDICAL) [wrist]Cerebral Oximetry (SOMANETICS) [forehead], BiS Index/EEG (ASPECT MEDICAL SYSTEMS) [corner of forehead],End-Tidal CO2/Respiratory Rate (PHASEIN/SMITHS MEDICAL/NIHON KOHDEN) [nose/mouth], Temperature/Heat Flux/Galvanic Skin Response (BODY MEDIA) [arm], Voice/Respiratory Rate/Cough [throat], Pulse Oximetry/Carbon Monoxide (MASIMO) [finger/toe/ear lobe]

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Second Generation, Fully Networked Smart Medical Vest

Energy Management

ECG Interface

MicroLEAP

Bluetooth Wireless Interface

Inertial Motion Sensors (3‐Axis Accelerometers 

and Gyroscopes)

Standard Sensor 

Interfaces

Personal Server

Bluetooth and IEEE 802.11

Wireless Interfaces

Personal Server to Database Server Transport

MicroLEAP 3-AxisMotion Sensors

MicroLEAP 3-AxisMotion Sensors

MicroLEAPECG Sensor

MicroLEAPPulse Oximeter

Personal Server

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Second Generation, Fully Networked Smart Medical Vest

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Global Hierarchical Decision Support System Architecture

A firefighter in operation

Physiologic Sensors Readings

Instantaneous PhysiologicalBehavior Assessment

Temporal/ContextualPhysiological Behavior Assessment

Prediction of Upcoming Physiological Behavior –

Trending

PersonalizedHealth Status Assessment

Personalization Module

Processing Sensors Signals

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Second Generation, Fully Networked Smart Medical Vests

The Ontological Physiologic Knowledgebase System – Top Level Vital Signs

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EmergencyCare

Respiratory

SkinTemperature

Cardio-Vascular

Current research focus

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Second Generation, Fully Networked Smart Medical Vests

Cardio-Vascular Sub-Tree of Emergency Care Ontology

Fragment of Emergency Care Hierarchy

* Alert Level I**Alert Level II*** Alert Level III**** Alert Level IV

Action 1: Do NothingAction 2: Verbal Status CheckAction 3: Buddy Status CheckAction 4: Leave the FieldAction 5: Send Rescue

Cardio-Vascular

HeartRate

BloodPressure

Junctional

Ventricular****

HeartRhythm

Sinus

Type I

Type IIBlock***

No Block

Regular

Irregular***

Normal

Tachy**

{HR>100}

Brady*

{HR< 50}

Abnormal****

Normal**

Block

40 ≤ HR≤ 50***

HR ≤ 40****

Type II or IIIor Other

Action 4/5

EmergencyCare*

Action 2/3

Action 4/5

Action 1

Action 2

Action 3/4

Action 3

No Block Action 3

Type I Action 3

Type (II or III)**** Action 4

Other Action 3/4

Irregular***

No Block Action 3

Block

Type I Action 3/4

Action 4/5

RegularBlock***

No Block

Type I Action 3

Type (II or III)****

or Other

Action 4/5

Action 2/3

Action 4

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Type II**** Action 4

Other Action 3/4

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Second Generation, Fully Networked Smart Medical Vests

Hierarchical Decision Support System – Cardio-Vascular Sub-Tree

HighBP>160

100 < BP ≤ 160 80 < BP ≤ 90***

BP ≤ 80****BP ≤ 100

Cardio-Vascular

EmergencyCare*

Fragment of Emergency Care Hierarchy

Action 1: Do NothingAction 2: Verbal Status CheckAction 3: Buddy Status CheckAction 4: Leave the FieldAction 5: Send Rescue

HeartRhythm

BloodPressure

High**

{>100}Go to HrhHeart

Rate

Normal{50 ≤ HR ≤ 100}

Action 1

{<50}Low*

*Go to Hrh

Action 1

Action 3/4

160 < BP ≤ 180**

180 < BP ≤ 200***

200 < BP ≤ 220****

BP > 220****

90 < BP ≤ 100**

Action 2

Action 2

Action 3/4

Action 2/3

Action 4/5

Action 4/5

Normal

Low*

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* Alert Level I**Alert Level II*** Alert Level III**** Alert Level IV

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Second Generation, Fully Networked Smart Medical Vests

Hierarchical Decision Support System – Respiratory Sub-Tree

Respiratory

Cough**

Respiratory Rate

Fragment of Emergency Care Hierarchy

Action 1: Do NothingAction 2: Verbal Status CheckAction 3: Buddy Status CheckAction 4: Leave the FieldAction 5: Send Rescue

EmergencyCare*

8 < BP ≤ 205< RR ≤ 8***

RR ≤ 5****

RR>20High

Normal

BP ≤ 8Low*

*

Action 1

20 < RR ≤ 30** Action 2

Action 4/5

RR >30*** Action 3/4

Action 2/3

Able to talk Action 2

Unable to talk**** Action 4/5

Fragmented Sentences*** Action 3

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* Alert Level I**Alert Level II*** Alert Level III**** Alert Level IV

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Second Generation, Fully Networked Smart Medical Vest

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1 – Each physiological parameter yields a certain action and alert2 – Challenge is to combine the different alerts and actions to yield a single recommendation?3 – No fixed solution 4 – Machine Learning through use of physiological data labeled by medical experts5 – Modular, Computational Efficiency

Hierarchical Decision Support System – the Parsing Algorithm

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Second Generation, Fully Networked Smart Medical Vest

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• For Radical, Moderate and Conservative strategies, we have compared our iterativelearning method with Naïve Bayes, SVM (with linear kernel), and with NeuralNetworks (Multilayer Perceptron), which are the popular classification methods.

• The following accuracy results were obtained

Learning the Acuity Matrix (continued)

Classifier

Strategy

Our method Naïve Bayes SVM Neural Networks1 hidden layer

Neural Networks Adaptive # of hidden layers

Conservative 98.56% 68.82% 75.86% 79.45% 93.30%

Moderate 88.79% 66.95% 46.2% 61.92% 83.40%

Radical 95.69% 77.15% 89.65% 65.08% 89.09%

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Second Generation, Fully Networked Smart Medical Vest

Health Status Recommendations – Current, Contextual and Prediction

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Conservative versus Moderate recommendationsInstantaneous versus Receding Horizon recommendations

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Hierarchical Decision Support System – Personalizing the System

• Normal values of the physiological parameters differ fromindividual to individual

• The Hierarchical Decision Support needs to be “personalized”in order to accurately issue alerts and alarms

• Personalization is done using data collected during trainingexercises

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Second Generation, Fully Networked Smart Medical Vest

0

20

40

60

80

100

120

140

160

0 50 100 150 200 250

Time (sec)

Pu

lse

Ra

te (

bp

m)

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120

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160

180

0 50 100 150 200 250

Time (sec)

Pu

lse

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bp

m)

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Variation of heart-rate for three different individuals while performing the same exercise

Necessity for Personalization

Individual A Individual B

0

20

40

60

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120

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160

180

0 100 200 300 400

Time (sec)

Pu

lse

Ra

te (

bp

m)

Individual C

Heart Rate

Time

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Hierarchical Decision Support System – Activity Aware

• Normal values of the physiological parameters also depend on the physical activity being performed

• The Hierarchical Decision Support needs to be “Activity-Aware” in order to accurately issue alerts and alarms

• Activity type can be inferred from motion sensors which are also part of the sensor suite

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Second Generation, Fully Networked Smart Medical Vest

Activity Recognition

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Foot pressure readings Vertical acceleration readings

Sedentary

Walk

Jog

Walk +Weight

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Second Generation, Fully Networked Smart Medical Vest

Sensor Suite and DSS – Current prototypes

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Sensor suite and DSS

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ConclusionsDevelopment of a fully networked smart medical vest

Energy Aware

Intelligent Hierarchical Decision Support System

Personalized

Activity Aware

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Second Generation, Fully Networked Smart Medical Vest

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Working for UtopiaCutting edge research environment

Variety of disciplines – Applied mathematics, Artificial Intelligence, Computer Vision, Wireless Communication Networks, Robotics

Contact:[email protected]@utopiacompression.comSee also Jacob or Anurag at the workshop

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