segmentation
DESCRIPTION
Segmentation. outward. inward. Three Conformations. pre-power stroke state in smooth muscle (PDB - 1BR1). pre-power stroke state in scallop muscle (PDB - 1 QVI). Myosin-V with ADP (PDB - 1W7I). F-actin. CC= 0.64. CC= 0.58. CC= 0.53. CC= 0.41. CC= 0.42. CC= 0.42. - PowerPoint PPT PresentationTRANSCRIPT
![Page 1: Segmentation](https://reader035.vdocument.in/reader035/viewer/2022062500/56815ad9550346895dc8a632/html5/thumbnails/1.jpg)
Segmentation
outward
inward
![Page 2: Segmentation](https://reader035.vdocument.in/reader035/viewer/2022062500/56815ad9550346895dc8a632/html5/thumbnails/2.jpg)
Three Conformations
Myosin-V with ADP (PDB - 1W7I)
pre-power stroke state in scallop muscle (PDB - 1QVI)
F-actin
pre-power stroke state in smooth muscle (PDB - 1BR1)
![Page 3: Segmentation](https://reader035.vdocument.in/reader035/viewer/2022062500/56815ad9550346895dc8a632/html5/thumbnails/3.jpg)
CC= 0.64 CC= 0.53
CC= 0.42
CC= 0.58
CC= 0.42CC= 0.41
outward
inward
Docking by SITUS (colores)
ADPmyosin-V
Scallop-like pre-power stroke
smooth muscle-like pre-power stroke
![Page 4: Segmentation](https://reader035.vdocument.in/reader035/viewer/2022062500/56815ad9550346895dc8a632/html5/thumbnails/4.jpg)
outward
inward
ADPmyosin-V
Scallop-like pre-power stroke
smooth muscle-like pre-power stroke
Docking by SITUS (colores)
CC= 0.64 CC= 0.53
CC= 0.42
CC= 0.58
CC= 0.42CC= 0.41
![Page 5: Segmentation](https://reader035.vdocument.in/reader035/viewer/2022062500/56815ad9550346895dc8a632/html5/thumbnails/5.jpg)
CC= 0.64outward
Docking by SITUS (myoV-ADP)
ADPmyosin-V
![Page 6: Segmentation](https://reader035.vdocument.in/reader035/viewer/2022062500/56815ad9550346895dc8a632/html5/thumbnails/6.jpg)
CC= 0.82outward
Normal Mode Flexible Fitting (myoV-ADP)
ADPmyosin-V
![Page 7: Segmentation](https://reader035.vdocument.in/reader035/viewer/2022062500/56815ad9550346895dc8a632/html5/thumbnails/7.jpg)
CC= 0.58
Docking by SITUS (scallop-like)
outward
Scallop-like pre-power stroke
![Page 8: Segmentation](https://reader035.vdocument.in/reader035/viewer/2022062500/56815ad9550346895dc8a632/html5/thumbnails/8.jpg)
CC= 0.77
Normal Mode Flexible Fitting (scallop-like)
outward
Scallop-like pre-power stroke
![Page 9: Segmentation](https://reader035.vdocument.in/reader035/viewer/2022062500/56815ad9550346895dc8a632/html5/thumbnails/9.jpg)
Fitted “scallop-like” on F-actin
F-actin F-actin Myosin-V with ADP (PDB - 1W7I)
pre-power stroke state in scallop myosin (PDB - 1QVI)
pre-power stroke state in smooth muscle myosin (PDB - 1BR1)