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UNIVERSITY OF ZAGREB SCHOOL OF MEDICINE
Plan of the course
Physiology
Academic year 2019/2020
izv. prof. dr. sc. Vladiana Crljen
I. COURSE AIMS
The overall aim of the Physiology course is to increase understanding the fundamental mechanisms of how cells and organsystems function, how they are regulated under normal physiological conditions and also how their function is changed inpathological conditions, since some diseases could arise directly from abnormalities in their regulation.
Lecture hours: 33
Seminar hours: 102
Practical hours: 50
Total hours: 185
ECTS 21.0
II. COURSE STRUCTURE
Course hours:
Lectures: 33
Seminar: 102
Practicum: 50
Total hours: 185
Physiology curriculum is organized into learning units based on major body systems and functions as:
Cell, muscle physiology, cardiovascular physiology, respiratory physiology, physiology of flying and diving, renalphysiology, gastrointestinal physiology, metabolism and thermoregulation, physiology of the endocrine system, physiologyof the pregnancy and lactation, fetal and newborn physiology, physiology of the sport.
III. PLAN OF THE COURSE AND COURSE SCHEDULE
BLOCKS OF THE COURSE
Number of blocks: 1Blocknumber Start End
1. 20.1.2020 7.4.2020
BLOCKS OF THE COURSE SHEME
Block 1
Date Time Group Coursehours type Theme Teaching staff
Monday20.1.2020.
08:00-08:45;MEF FiziologijaPredavaonica
ALL Exam L1 - INTRODUCING THE PHYSIOLOGYCOURSE
izv. prof. dr. sc.Vladiana Crljen
08:45-10:15;MEF FiziologijaPredavaonica
ALL Exam L2 - INTRODUCTION AND MEMBRANETRANSPORT
izv. prof. dr. sc.Mirza Žižak
10:30-12:00;MEF FiziologijaPredavaonica
ALL Lectures L3 - ELECTRICAL PROPERTIES OF THEMEMBRANE
prof. dr. sc. HrvojeBanfić
12:30-14:45;MEF FiziologijaPredavaonica
A Seminar S1 - CELL izv. prof. dr. sc.Mirza Žižak
15:00-17:15;MEF FiziologijaPredavaonica
B Seminar S1 - CELL izv. prof. dr. sc.Mirza Žižak
Tuesday21.1.2020.
08:00-09:30;MEF FiziologijaPredavaonica
ALL Lectures L4 - SMOOTH MUSCLE prof. dr. sc. HrvojeBanfić
09:45-12:00;MEFKompjutorskaučionica
A Practicum P1 - MEMBRANE POTENTIAL part 1
dr. sc. Alan Šućur,dr. sc. Nikola Habek,izv. prof. dr. sc.Tomislav Kelava
12:15-14:30;MEFKompjutorskaučionica
B Practicum P1 - MEMBRANE POTENTIAL part 1
dr. sc. Hrvoje Lalić,dr. sc. Darja Flegar,izv. prof. dr. sc.Mirza Žižak
12:30-14:45;MEF FiziologijaPredavaonica
A Seminar S2 - MUSCLE prof. dr. sc. HrvojeBanfić
15:00-17:15;MEF FiziologijaPredavaonica
B Seminar S2 - MUSCLE prof. dr. sc. HrvojeBanfić
Wednesday22.1.2020. 10:00-12:15;
MEFKompjutorskaučionica
B Practicum P1 - MEMBRANE POTENTIAL part 2
izv. prof. dr. sc.Mirza Žižak, dr. sc.Alan Šućur, izv.prof. dr. sc.Tomislav Kelava
12:30-14:45;MEF FiziologijaPredavaonica
B Seminar S3 - HEART I izv. prof. dr. sc.Mirza Žižak
12:30-14:45;MEFKompjutorskaučionica
A Practicum P1 - MEMBRANE POTENTIAL part 2dr. sc. Hrvoje Lalić,dr. sc. Alan Šućur,dr. sc. Nikola Habek
15:00-17:15;MEF FiziologijaPredavaonica
A Seminar S3 - HEART I izv. prof. dr. sc.Mirza Žižak
Thursday23.1.2020.
08:00-10:15;MEF FiziologijaPredavaonica
A Seminar S5 - ECG izv. prof. dr. sc.Mirza Žižak
10:30-12:00;MEF FiziologijaPredavaonica
ALL Lectures L5 - INTORDUCING CARDIOVASCULARSYSTEM
izv. prof. dr. sc.Mirza Žižak
12:30-14:45;MEF FiziologijaPredavaonica
B Seminar S5 - ECG izv. prof. dr. sc.Mirza Žižak
Friday24.1.2020.
08:00-10:15;MEF FiziologijaPredavaonica
A Seminar S4 - HEART II dr. sc. Hrvoje Lalić
10:30-13:30;MEF Fiziologija Ikat A Practicum P2 - ECG, RR
izv. prof. dr. sc.AleksandraDugandžić, dr. sc.Nikola Habek, dr. sc.Alan Šućur
10:30-12:45;MEF FiziologijaPredavaonica
B Seminar S4 - HEART IIizv. prof. dr. sc.Vesna LukinovićŠkudar
Date Time Group Coursehours type Theme Teaching staff
13:30-16:30;MEF Fiziologija Ikat B Practicum P2 - ECG, RR
izv. prof. dr. sc.AleksandraDugandžić, dr. sc.Nikola Habek, dr. sc.Vilma Dembitz
Monday27.1.2020.
08:30-10:00;MEF FiziologijaPredavaonica
A Seminar S6 - INTEGRATION I (Cell, Electricalproperties of the membrane, Heart) dr. sc. Darja Flegar
10:15-11:45;MEF FiziologijaPredavaonica
B Seminar S6 - INTEGRATION I (Cell, Electricalproperties of the membrane, Heart) dr. sc. Darja Flegar
Tuesday28.1.2020.
08:00-08:45;MEF Biološka ALL Seminar S6 - INTEGRATION I (Cell, El. prop. of the
membrane, Heart)/TESTizv. prof. dr. sc.Tomislav Kelava
08:00-08:45;MEF Novavijećnica
ALL Seminar S6 - INTEGRATION I (Cell,El. prop. of themembrane, Heart)/ TEST dr. sc. Darja Flegar
09:30-11:00;MEF FiziologijaPredavaonica
ALL Lectures L6 - INTRODUCING CIRCULATION;LAPLACE LAW
izv. prof. dr. sc.Vladiana Crljen
11:15-13:30;MEF FiziologijaPredavaonica
A Seminar S7 - C IRCULATION I- Arterial pressureand circulation
izv. prof. dr. sc.Tomislav Kelava
13:45-16:00;MEF FiziologijaPredavaonica
B Seminar S7 - C IRCULATION I- Arterial pressureand circulation
izv. prof. dr. sc.Tomislav Kelava
Wednesday29.1.2020.
10:30-12:45;MEF FiziologijaPredavaonica
B Seminar S8 - MICROCIRCULATIONizv. prof. dr. sc.AleksandraDugandžić
13:00-15:15;MEF FiziologijaPredavaonica
A Seminar S8 - MICROCIRCULATIONizv. prof. dr. sc.AleksandraDugandžić
15:30-18:30;MEF FiziologijaVježbaonica A Practicum P5 - PLETISMOGRAPHY, POLYGRAPHY
dr. sc. Hrvoje Lalić,izv. prof. dr. sc.Tomislav Kelava, dr.sc. Nikola Habek
Thursday30.1.2020.
08:00-10:15;MEF FiziologijaPredavaonica
B Seminar S9 - C IRCULATION III-CO & venousreturn, spec.org. circulation
izv. prof. dr. sc.Mirza Žižak
10:30-11:15;MEF FiziologijaPredavaonica
ALL Lectures L7 - AUTONOMIC NERVOUS SYSTEM doc. dr. sc. MarijaRenić
11:30-13:45;MEF FiziologijaPredavaonica
A Seminar S9 - C IRCULATION III - CO & venousreturn, spec.org. circulation
izv. prof. dr. sc.Mirza Žižak
Friday31.1.2020.
09:00-11:15;MEF FiziologijaPredavaonica
A Seminar S10 - C IRCULATION II Regulation ofarterial pressure
izv. prof. dr. sc.Vladiana Crljen
11:30-13:45;MEF FiziologijaPredavaonica
B Seminar S10 - C IRCULATION II Regulation ofarterial pressure
izv. prof. dr. sc.Vladiana Crljen
14:30-17:30;MEF FiziologijaVježbaonica B Practicum P5 - PLETISMOGRAPHY, POLYGRAPHY
dr. sc. Alan Šućur,dr. sc. Darja Flegar,dr. sc. VilmaDembitz
Monday3.2.2020.
11:15-12:45;MEFWickerhauser
ALL Lectures L8 - BLOOD CLOTTING izv. prof. dr. sc.Mirza Žižak
13:00-15:15;MEF Fiziologija Ikat A Practicum P4 - BLOOD CLOTTING
dr. sc. VilmaDembitz, dr. sc. AlanŠućur, dr. sc. DarjaFlegar
Date Time Group Coursehours type Theme Teaching staff
16:30-18:45;MEF Fiziologija Ikat B Practicum P4 - BLOOD CLOTTING
izv. prof. dr. sc.Vesna LukinovićŠkudar, dr. sc.Vilma Dembitz, dr.sc. Nikola Habek
Tuesday4.2.2020.
08:00-08:45;MEF FiziologijaPredavaonica
ALL Lectures L9 - ERYTHROCYTE, ANEMIA ANDPOLYCYTHEMIA
izv. prof. dr. sc.Vesna LukinovićŠkudar
09:00-12:45;MEF FiziologijaVježbaonica A Practicum P3 - ERYTHROCYTE COUNT, Ht, Hb
izv. prof. dr. sc.Vesna LukinovićŠkudar, dr. sc.Nikola Habek, dr. sc.Vilma Dembitz
13:00-16:45;MEF FiziologijaVježbaonica B Practicum P3 - ERYTHROCYTE COUNT, Ht, Hb
izv. prof. dr. sc.Vesna LukinovićŠkudar, dr. sc.Darja Flegar, DinoŠisl, dr. med.
Wednesday5.2.2020.
08:30-10:00;MEF FiziologijaPredavaonica
A Seminar S11 - INTEGRATION II(C IRCULATION) izv. prof. dr. sc.Mirza Žižak
10:30-12:00;MEF FiziologijaPredavaonica
B Seminar S11 - INTEGRATION II (C IRCULATION) izv. prof. dr. sc.Mirza Žižak
Friday7.2.2020.
15:30-16:15;MEF Čačković ALL Seminar S11 - INTEGRATION II (CVS)/TEST izv. prof. dr. sc.
Mirza Žižak15:30-16:15;MEF FiziologijaVježbaonica
ALL Seminar S11 - INTEGRATION II (CVS)/TEST dr. sc. Nikola Habek
Tuesday11.2.2020. 08:30-10:00;
MEF Čačković ALL Exam COLLOQUIUM P1izv. prof. dr. sc.Vesna LukinovićŠkudar
08:30-10:00;MEF Novavijećnica
ALL Exam COLLOQUIUM P1 izv. prof. dr. sc.Tomislav Kelava
11:00-12:30;MEF FiziologijaPredavaonica
ALL Lectures L10 - INTRODUCING RESPIRATORYSYSTEM
prof. dr. sc. DoraVišnjić
Wednesday12.2.2020.
08:30-10:45;MEF Mašek A Seminar S12 - RESPIRATION I - Pulmonary
ventilation and circulationprof. dr. sc. DoraVišnjić
11:00-13:15;MEF FiziologijaPredavaonica
B Seminar S12 - RESPIRATION I - Pulmonaryventilation and circulation
prof. dr. sc. DoraVišnjić
14:00-17:00;MEF FiziologijaVježbaonica B Practicum P6 - SPIROMETRY
izv. prof. dr. sc.Vesna LukinovićŠkudar, dr. sc.Hrvoje Lalić, dr. sc.Darja Flegar
Thursday13.2.2020.
08:00-10:15;MEFWickerhauser
B Seminar S13 - RESPIRATION II - Principles of gasexchange; CO2 & O2 transport
prof. dr. sc. DoraVišnjić
11:45-14:00;MEFWickerhauser
A Seminar S13 - RESPIRATION II - Principles of gasexchange; CO2 & O2 transport
prof. dr. sc. DoraVišnjić
14:30-17:30;MEF FiziologijaVježbaonica A Practicum P6 - SPIROMETRY
izv. prof. dr. sc.Vesna LukinovićŠkudar, dr. sc.Nikola Habek, DinoŠisl, dr. med.
Friday14.2.2020.
08:30-10:45;MEFWickerhauser
A Seminar S14 - RESPIRATION III - Regulation ofrespiration
izv. prof. dr. sc.Vesna LukinovićŠkudar
11:00-12:30;MEFWickerhauser
ALL Lectures L11 - FLYING AND DIVINGizv. prof. dr. sc.AleksandraDugandžić
Date Time Group Coursehours type Theme Teaching staff
12:45-15:00;MEFWickerhauser
B Seminar S14 - RESPIRATION III - Regulation ofrespiration
izv. prof. dr. sc.Vesna LukinovićŠkudar
Monday17.2.2020.
08:30-10:00;MEF FiziologijaPredavaonica
A Seminar S15 - INTEGRATION III prof. dr. sc. DoraVišnjić
12:45-14:15;MEF FiziologijaPredavaonica
B Seminar S15 - INTEGRATION III prof. dr. sc. DoraVišnjić
Tuesday18.2.2020.
08:15-09:00;MEF Čačković ALL Seminar S15 - INTEGRATION III (Respiratory
system)/TESTprof. dr. sc. DoraVišnjić
08:15-09:00;MEF FiziologijaVježbaonica
ALL Seminar S15 - INTEGRATION III (Respiratorysystem)/TEST
izv. prof. dr. sc.Vesna LukinovićŠkudar
12:00-13:30;MEF FiziologijaPredavaonica
ALL Lectures L12 - INTRODUCING RENAL SYSTEM prof. dr. sc. HrvojeBanfić
Wednesday19.2.2020.
08:00-10:15;MEFWickerhauser
A Seminar S16 - BODY FLUIDSizv. prof. dr. sc.Vesna LukinovićŠkudar
10:30-12:45;MEFWickerhauser
B Seminar S16 - BODY FLUIDSizv. prof. dr. sc.Vesna LukinovićŠkudar
Thursday20.2.2020.
08:00-10:15;MEF Mašek A Seminar S17 - KIDNEY I - Structure, GFR,
C learanceizv. prof. dr. sc.Mirza Žižak
10:30-12:45;MEF Mašek B Seminar S17 - KIDNEY I - Structure, GFR,
C learanceizv. prof. dr. sc.Mirza Žižak
Friday21.2.2020.
08:00-10:15;MEF Mašek A Seminar S18 - KIDNEY II-Tub trans.&proc.,Reg.of
K,Ca,HPO4&Mgizv. prof. dr. sc.Vladiana Crljen
10:30-11:15;MEF Fiziologija Ikat B Practicum P7 - PROBLEM SOLVING
izv. prof. dr. sc.Vladiana Crljen, dr.sc. Alan Šućur, dr.sc. Vilma Dembitz
11:15-12:45;MEFKompjutorskaučionica
B Practicum P7 - PROBLEM SOLVING
izv. prof. dr. sc.Vladiana Crljen, dr.sc. Alan Šućur, dr.sc. Vilma Dembitz
12:45-13:30;MEF Fiziologija Ikat B Practicum P7 - PROBLEM SOLVING
izv. prof. dr. sc.Vladiana Crljen, dr.sc. Alan Šućur, dr.sc. Vilma Dembitz
14:00-16:15;MEFWickerhauser
B Seminar S18 - KIDNEY II-Tub trans.&proc.,Reg.ofK,Ca,HPO4&Mg
izv. prof. dr. sc.Vladiana Crljen
Monday24.2.2020. 08:00-08:45;
MEF Fiziologija Ikat
A Practicum P7 - PROBLEM SOLVING
izv. prof. dr. sc.Vladiana Crljen, dr.sc. Alan Šućur, dr.sc. Vilma Dembitz
08:45-10:15;MEFKompjutorskaučionica
A Practicum P7 - PROBLEM SOLVING
izv. prof. dr. sc.Vladiana Crljen, dr.sc. Alan Šućur, dr.sc. Vilma Dembitz
10:15-11:00;MEF Fiziologija Ikat A Practicum P7 - PROBLEM SOLVING
izv. prof. dr. sc.Vladiana Crljen, dr.sc. Alan Šućur, dr.sc. Vilma Dembitz
11:15-13:30;MEFWickerhauser
A Seminar S19 - KIDNEYIII-Regulation of ECV &osmolarity, Urine concetration
izv. prof. dr. sc.Vladiana Crljen
Date Time Group Coursehours type Theme Teaching staff
14:00-16:15;MEFWickerhauser
B Seminar S19 - KIDNEYIII-Regulation of ECV &osmolarity, Urine concentration
dr. sc. VilmaDembitz
Tuesday25.2.2020.
08:30-10:00;MEFWickerhauser
ALL Lectures L13 - ACID BASE BALANCEizv. prof. dr. sc.AleksandraDugandžić
10:15-12:30;MEFWickerhauser
A Seminar S20 - ACID BASE BALANCE prof. dr. sc. HrvojeBanfić
12:45-15:00;MEFWickerhauser
B Seminar S20 - ACID BASE BALANCE prof. dr. sc. HrvojeBanfić
Wednesday26.2.2020.
09:00-10:30;MEF Novavijećnica
A Seminar S21 - INTEGRATION IV (Renal system) izv. prof. dr. sc.Vladiana Crljen
10:45-12:15;MEF Mašek B Seminar S21 - INTEGRATION IV (Renal sytem) izv. prof. dr. sc.
Vladiana CrljenThursday27.2.2020.
10:00-10:45;MEF Čačković ALL Seminar S21 - INTEGRATION IV (Renal
system)/TESTizv. prof. dr. sc.Vladiana Crljen
10:00-10:45;MEF Novavijećnica
ALL Seminar S21 - INTEGRATION IV (Renalsystem)/TEST dr. sc. Alan Šućur
Tuesday3.3.2020.
09:00-10:30;MEF Čačković ALL Exam COLLOQUIUM P2 dr. sc. Darja Flegar
09:00-10:30;MEF Novavijećnica
ALL Exam COLLOQUIUM P2 dr. sc. Alan Šućur
11:30-13:00;MEF Novavijećnica
ALL Lectures L14 - INTRODUCING GASTROINTESTINALPHYSIOLOGY
prof. dr. sc. HrvojeBanfić
Wednesday4.3.2020.
08:00-10:15;MEFWickerhauser
A Seminar S22 - GI I - Principles of GI function,motility, nervous control, circulation
izv. prof. dr. sc.Vesna LukinovićŠkudar
10:30-12:45;MEFWickerhauser
B Seminar S22 - GI I Principles of GI function,motility, nervous control, circulation
izv. prof. dr. sc.Vesna LukinovićŠkudar
Thursday5.3.2020.
08:30-10:45;MEFWickerhauser
A Seminar S23 - GI II - Secretory functions,digestion and absorption
prof. dr. sc. DoraVišnjić
11:00-13:15;MEFWickerhauser
B Seminar S23 - GI II - Secretory functions,digestion and absorption
prof. dr. sc. DoraVišnjić
Friday6.3.2020.
08:00-10:15;MEFWickerhauser
A Seminar S24 - GI III - Metab. of carbohydrates,lipids and proteins
prof. dr. sc. HrvojeBanfić
10:30-12:45;MEFWickerhauser
B Seminar S24 - GI III - Metab. of carbohydrates,lipids and proteins
prof. dr. sc. HrvojeBanfić
Monday9.3.2020.
08:00-10:15;MEFWickerhauser
A Seminar S25 - TERMOREGUALTION, METABOLISM izv. prof. dr. sc.Vladiana Crljen
10:30-12:45;MEFWickerhauser
B Seminar S25 - TERMOREGUALTION, METABOLISM izv. prof. dr. sc.Vladiana Crljen
Tuesday10.3.2020.
09:00-10:30;MEFWickerhauser
A Seminar S26 - INTEGRATION V (Gastrointestinalsystem)
izv. prof. dr. sc.Vesna LukinovićŠkudar
10:45-12:15;MEFWickerhauser
B Seminar S26 - INTEGRATION V (Gastrointestinalsystem)
izv. prof. dr. sc.Vesna LukinovićŠkudar
Date Time Group Coursehours type Theme Teaching staff
11:00-14:00;MEF Fiziologija Ikat A Practicum P8 - BASAL METABOLISM
izv. prof. dr. sc.Vladiana Crljen, dr.sc. Hrvoje Lalić, dr.sc. Alan Šućur
14:30-17:30;MEF Fiziologija Ikat B Practicum P8 - BASAL METABOLISM
izv. prof. dr. sc.Vladiana Crljen, dr.sc. Hrvoje Lalić, dr.sc. Alan Šućur
Wednesday11.3.2020. 08:15-09:00;
MEF Čačković ALL Seminar S26 - INTEGRATION V (GI SYSTEM)/TESTizv. prof. dr. sc.Vesna LukinovićŠkudar
08:15-09:00;MEF Biološka ALL Seminar S26 - INTEGRATION V (GI SYSTEM)/TEST dr. sc. Nikola Habek
09:30-11:00;MEF Čačković ALL Lectures L15 - INTRODUCING ENDOCRINE SYSTEM prof. dr. sc. Dora
VišnjićThursday12.3.2020.
08:00-10:15;MEF Biološka A Seminar S27 - PITUITARY GLAND dr. sc. Nikola Habek
10:30-12:45;MEF Biološka B Seminar S27 - PITUITARY GLAND dr. sc. Nikola Habek
Friday13.3.2020.
08:00-10:15;MEFWickerhauser
A Seminar S28 - THYROID GLANDizv. prof. dr. sc.Vesna LukinovićŠkudar
10:30-12:45;MEFWickerhauser
B Seminar S28 - THYROID GLANDizv. prof. dr. sc.Vesna LukinovićŠkudar
11:00-14:00;MEF Fiziologija Ikat A Practicum P9 - THYROID HORMONE & O2
CONSUMPTION IN RATS
dr. sc. Darja Flegar,dr. sc. Hrvoje Lalić,dr. sc. VilmaDembitz
14:30-17:30;MEF Fiziologija Ikat B Practicum P9 - THYROID HORMONE & O2
CONSUMPTION IN RATS
dr. sc. Hrvoje Lalić,Barbara Tomić, dr.med., izv. prof. dr.sc. Vladiana Crljen
Monday16.3.2020.
09:00-11:15;MEFWickerhauser
A Seminar S29 - CALCIUM, PHOSPHATE BALANCE prof. dr. sc. DoraVišnjić
11:30-13:45;MEFWickerhauser
B Seminar S29 - CALCIUM, PHOSPHATE BALANCE prof. dr. sc. DoraVišnjić
12:00-15:00;MEF Fiziologija Ikat A Practicum P10 - THORN
dr. sc. VilmaDembitz, dr. sc. AlanŠućur, dr. sc. HrvojeLalić
Tuesday17.3.2020.
08:00-10:15;MEFWickerhauser
B Seminar S30 - ADRENAL GLAND dr. sc. Nikola Habek
10:30-12:45;MEFWickerhauser
A Seminar S30 - ADRENAL GLAND dr. sc. Nikola Habek
10:30-13:30;MEF Fiziologija Ikat B Practicum P10 - THORN
izv. prof. dr. sc.Vladiana Crljen, dr.sc. Alan Šućur, dr.sc. Hrvoje Lalić
Wednesday18.3.2020.
08:00-10:15;MEFWickerhauser
B Seminar S31 - REPRODUCTIVE PHYSIOLOGY ANDMALE HORMONES
izv. prof. dr. sc.AleksandraDugandžić
10:30-12:45;MEFWickerhauser
A Seminar S31 - REPRODUCTIVE PHYSIOLOGY ANDMALE HORMONES
izv. prof. dr. sc.AleksandraDugandžić
Thursday19.3.2020.
08:00-10:15;MEFWickerhauser
B Seminar S32 - REPRODUCTIVE PHYSIOLOGY ANDFEMALE HORMONES
izv. prof. dr. sc.AleksandraDugandžić
Date Time Group Coursehours type Theme Teaching staff
10:30-12:45;MEFWickerhauser
A Seminar S32 - REPRODUCTIVE PHYSIOLOGY ANDFEMALE HORMONES
izv. prof. dr. sc.AleksandraDugandžić
Monday23.3.2020.
08:00-10:15;MEFWickerhauser
A Seminar S33 - BLOOD GLUCOSE, INSULIN,GLUCAGON
prof. dr. sc. DoraVišnjić
10:30-13:30;MEF Fiziologija Ikat A Practicum P11 - OGTT
dr. sc. Hrvoje Lalić,Barbara Tomić, dr.med., dr. sc. AlanŠućur
Tuesday24.3.2020.
08:00-10:15;MEFWickerhauser
B Seminar S33 - BLOOD GLUCOSE, INSULIN,GLUCAGON
prof. dr. sc. DoraVišnjić
10:30-13:30;MEF Fiziologija Ikat B Practicum P11 - OGTT
dr. sc. Hrvoje Lalić,dr. sc. VilmaDembitz, dr. sc. AlanŠućur
Wednesday25.3.2020.
08:00-09:30;MEF FiziologijaPredavaonica
ALL Lectures L16 - PREGNANCY AND LACTATIONizv. prof. dr. sc.Vesna LukinovićŠkudar
09:45-11:15;MEF FiziologijaPredavaonica
ALL Lectures L17 - FETAL AND NEWBORN PHYSIOLOGYizv. prof. dr. sc.AleksandraDugandžić
12:00-15:00;MEF FiziologijaVježbaonica A Practicum P12 - ÅSTRAND
dr. sc. VilmaDembitz, dr. sc.Hrvoje Lalić, DinoŠisl, dr. med.
15:15-18:15;MEF FiziologijaVježbaonica B Practicum P12 - ÅSTRAND
dr. sc. Darja Flegar,dr. sc. VilmaDembitz, BarbaraTomić, dr. med.
Thursday26.3.2020. 08:00-09:30;
MEFWickerhauser
A Seminar
S34 - INTEGRATION VI (Endocrinesystem; Pregnancy and lactation, Fetaland newborn physiology; Sportsphysiology)
dr. sc. Nikola Habek
09:45-11:15;MEFWickerhauser
ALL Lectures L18 - SPORTS PHYSIOLOGY prof. dr. sc. HrvojeBanfić
11:30-13:00;MEFWickerhauser B Seminar
S34 - INTEGRATION VI (Endocrinesystem; Pregnancy and lactation, Fetaland newborn physiology; Sportsphysiology)
dr. sc. Nikola Habek
Friday27.3.2020.
10:00-10:45;MEF Čačković ALL Seminar S34 - INTEGR VI (End.S.;Preg.Lac.;
Fet.New; Spor.) /TESTizv. prof. dr. sc.Vladiana Crljen
10:00-10:45;MEF Novavijećnica
ALL Seminar S34 - INTEGR VI (End.S.;Preg.Lac.;Fet.New; Spor.) /TEST
izv. prof. dr. sc.AleksandraDugandžić
Tuesday31.3.2020.
10:00-11:30;MEF Biološka ALL Exam COLLOQUIUM P3 izv. prof. dr. sc.
Mirza Žižak10:00-11:30;MEF Novavijećnica
ALL Exam COLLOQUIUM P3 dr. sc. Nikola Habek
Friday3.4.2020.
13:00-16:45;MEF Čačković ALL Exam COLLOQUIUM P1 OR P2 prof. dr. sc. Hrvoje
BanfićThursday2.7.2020.
08:30-14:30;MEF FiziologijaPredavaonica
ALL Exam Examizv. prof. dr. sc.Tomislav Kelava, dr.sc. Alan Šućur
Tuesday14.7.2020.
08:30-14:30;MEF FiziologijaPredavaonica
ALL Exam Examizv. prof. dr. sc.Tomislav Kelava, dr.sc. Alan Šućur
Tuesday1.9.2020.
08:30-14:30;MEF FiziologijaVježbaonica
ALL Exam Examdr. sc. Darja Flegar,izv. prof. dr. sc.Vladiana Crljen
Date Time Group Coursehours type Theme Teaching staff
Tuesday15.9.2020.
08:30-14:30;MEF FiziologijaVježbaonica
ALL Exam Examdr. sc. Darja Flegar,izv. prof. dr. sc.Vladiana Crljen
Date Time Group Coursehours type Theme Teaching staff
LIST OF LECTURERS AND TEACHING STAFF
Prof. Hrvoje Banfić , Head of the Departement
Prof. Dora Višnjić
Assoc. Prof. Mirza Žižak
Assoc. Prof. Aleksandra Sinđić
Assoc. Prof. Vladiana Crljen
Assoc. Prof. Vesna Lukinović Škudar
Assoc. Prof. Tomislav Kelava
Assist Prof Marija Renić
Senior Instructor Hrvoje Lalić, MD, PhD
Senior Instructor Alan Šućur, MD, PhD
Senior Instructor Vilma Dembitz, MD, PhD
Instructor Darja Flegar, MD, MD, PhD
Instructor Nikola Habek, MD, PhD
Instructor Dino Šisl, MD
Instructor Barbara Tomić, MD
LIST OF EXAMINERS
Prof. Hrvoje Banfić
Prof. Dora Višnjić
Assoc. Prof. Mirza Žižak
Assoc. Prof. Aleksandra Dugandžić
Assoc. Prof. Vladiana Crljen
Assoc. Prof. Vesna Lukinović Škudar
Assoc. Prof. Tomislav Kelava
CONSULTATIONS
Prof. Hrvoje Banfić
Consultations: TUESDAY 16,00 - 18,00e-mail: [email protected].
Assoc. Prof. Vladiana CrljenConsultaions: WEDNESDAY 13,00-15,00e-mail: [email protected]
Prof. Dora VišnjićConsultations: MONDAY 14,00 - 16,00e-mail: [email protected]
Assoc. Prof. Mirza ŽižakConsultations: to be agreed
e-mail: [email protected]
Assoc. Prof. Aleksandra DugandžićConsultations: MONDAY 15,00-17,00 e-mail: [email protected]
Assoc. Prof. Vesna Lukinović-ŠkudarConsultations: FRIDAY 12,00 - 14,00e-mail: [email protected]
Assis. Prof. Marija Renić
Consultations: MONDAY 14,00-16,00
e-mail: [email protected]
Assoc. Prof. Tomislav KelavaConsultations: THURSDAY 12,00 - 14,00
e-mail: [email protected]
Senior Instructor Hrvoje Lalić, MD, PhD
Consultations: TUESDAY 14,00-16,00
e-mail: [email protected]
Senior Instructor Alan Šućur, MD, PhDConsultations: THURSDAY 13,00-15,00
e-mail: [email protected]
Senior Instructor Vilma Dembitz, MD, PhD
Consultations: WEDNESDAY 14,00-16,00
e-mail: [email protected]
Instructor Darja Flegar, MD, PhDConsultations: WEDNESDAY 14,00-16,00
e-mail: [email protected]
Instructor Nikola Habek, MD, PhD
Consultations: THURSDAY 12,00-14,00
e-mail: [email protected]
Instructor Dino Šisl, MD
Consultations: TUESDAY 14,00-16,00
e-mail: [email protected]
Instructor Barbara Tomić, MD
Consulatations: THURSDAY 14,00-16,00
e-mail: [email protected]
Lectures:
1. Introducing Physiology course (1)
2. Introducing membrane transport (2)
3. Electrical properties of the membrane (2)
4. Smooth muscle (2)
5. Introducing cardiovascular system (2)
6. Introducing circulation; Laplace law (2)
7. Autonomic nervous system (1)
8. Blood clotting (2)
9. Erythrocytes, anemia and polycythemia (1)
10. Introducing respiratory system (2)
11. Flying and diving (2)
12. Introducing renal system (2)
13. Acid-base balance (2)
14. Introducing gastrointestinal physiology (2)
15. Introducing endocrine system (2)
16. Pregnancy and lactation (2)
17. Fetal and Newborn Physiology (2)
18. Sports Physiology (2)
Seminar topics:
S SEMINAR TITLE Theme Chapter
1 CELL (3) Cell & membrane potential 4, 5
2 MUSCLE (3)
Structure of skeletal, smooth muscle, mechanism of contraction,control of skeletal muscle contraction excitation – contractioncoupling, neuromuscular transmission, mechanics and energetic ofskeletal muscle contraction, smooth muscle
6,7,8
3 HEART I (3)Cardiac muscle characteristic;
Electrophysiology of heart
9 (p 106-109),
10
4 HEART II (3) Cardiac function, cardiac cycle, cardiac defects (heart sounds) 9, 23 (p 283-285)
5
6
ECG, VECTOR ANALYSIS(3)
INTEGRATION I (3)
Electrocardiogram (ECG);
Vector analysis
Cell, Electrical properties of the membrane, Heart
TEST
11, 12
4-12,
23 (p 283-285)
7
CIRCULATION I (3) Arterial pressure and circulation 14, 15
8 MICROCIRCULATION (3)Fluid dynamics, the microcirculation and lymphatic;
Local control of blood flow 16, 17
9 CIRCULATION III (3)
Cardiac output and venous return;
Coronary circulation, skeletal muscle circulation
20,
21 (p259-264)
10 CIRCULATION II (3) Regulation of arterial pressure 18, 19
11 INTEGRATION II (3)
Case: Hypovolemic shock* Case: Acute myocardial infarction*
TEST
14-20,
21 (p 259-264)
12 RESPIRATION I (3)Pulmonary ventilation;
Pulmonary circulation 38, 39
13 RESPIRATION II (3)Principles of gas exchange;
Oxygen and carbon dioxide transport 40, 41
14 RESPIRATION III (3) Regulation of respiration 42
15 INTEGRATION III (3)Case: Obstructive lung disease*
TEST
31, 38-42; 43 (p 549-551)
16 BODY FLUIDS ANDELECTROLYTES (3) Edema, hyperhidration, dehydration 25
17 KIDNEY I (3) Structure of kidney and nephrons, glomerular filtration rate; Renalhemodynamics; Renal clearance
26, 27 28 (p365-368)
18 KIDNEY II (3) Transport and processing properties of tubular segments;Regulation of potassium, calcium, phosphate and magnesium
28 (p 347-365), 30 (p 389-399)
19 KIDNEY III (3) Regulation of extracellular fluid volume and osmolarity; Urineconcentration and dilution; Micturation; Dialysis
29, 30 (p 401--408), 32 (p 427-429, p 440-441)
20 ACID–BASE BALANCE(3) Acid-Base Balance 31
21 INTEGRATION IV (3)
Case: Acute glomerulonephritis*
Case: Secondary arterial hypertension*
TEST
25-31 (32)
22 GASTROINTESTINALSYSTEM I (3)
Principles of gastrointestinal function: motility, nervous control,blood circulation;
Reflexes, Propulsion and mixing of food
63, 64
23 GASTROINTESTINALSYSTEM II (3)
Secretory functions;
Digestion and absorption 65, 66
24 GASTROINTESTINALSYSTEM III (3)
Metabolism of carbohydrates, lipids, and proteins;Bilirubin, bile secretion, carbohydrate, nitrogen, lipid and proteinmetabolism, conjugation and detoxification; Liver
68, 69, 70, 71
25 THERMOREGULATIONAND METABOLISM (3)
Dietary balances, regulation of feeding; Metabolic rate;
Regulation of body temperature 72, 73, 74
26 INTEGRATION V (3)Case: Gastrointestinal system*
TEST 63-74
27 PITUITARY GLANDHORMONES (3) Pituitary hormones 76
28 THYROID GLANDHORMONES (3) Thyroid metabolic hormones 77
29CALCIUM ANDPHOSPHATE BALANCE (3)
Calcium and phosphate metabolism, vitamin D;
PTH and Calcitonin
80
30ADRENOCORTICAL
HORMONES (3)
Mineralocorticoids;
Glucocorticoids 78
31
32
REPRODUCTIVE
PHYSIOLOGY I (3)
REPRODUCTIVE
PHYSIOLOGY II (3)
Male hormones
Female hormones
81, 82
33REGULATION OFBLOOD GLUCOSECONCENTRATION (3)
Insulin, glucagon, liver, skeletal muscle, cortisol, catecholamine,growth hormone 79
34 INTEGRATION VI (3)
Endocrine system, Insulin sensitivity and glucoseuptake, Pregnancy and lactation, Fetal and newborn physiology
TEST 76-82
PRACTICAL WORK:
Students will be introduced through practical work to diagnostic tests that are routinely used in medicine. Due toethical reasons some of the exercises will be performed on animals (laboratory rats). In that way we will also show ourstudents how to work with laboratory animals, what can be helpful in their future scientific work. In line with that, somepracticals are designed as scientific experiments. When it is possible, the animal experiments are replaced with computersimulation.
Practical work topics:
1. MEMBRANE POTENTIAL - PART 1 and 2 (6) - LMS, Gu. 4, 5
2. ECG. MEASURING ARTERIAL BLOOD PRESSURE. (4) - LMS, Gu 11, 12,
14 (p 172-175),
15 (180-184)
3. ERYTROCYTE COUNT. HAEMOGLOBIN. HEMATOCRIT. SEDIMENTATION RATE. (5) -
LMS, Gu 33
4. BLOOD CLOTTING TESTS (3) - LMS, Gu 37
5. PLETISMOGRAPHY, POLIGRAPHY (4) - LMS
6. SPIROMETRY (4) - LMS, Gu 38 (p 501-503); 43 (p 549-551)
7. PROBLEM SOLVING (model KIDNEY); ERYTROCYTE - MEMBRANE RESISTANCY (4)
- LMS,
Gu 26, 27,
28, 29
8. MEASURING THE RATE OF BASAL METABOLISM IN HUMAN. (4) - LMS, Gu 73
(p 905-909)
9. EFFECT OF THYROID HORMONE ON OXYGEN CONSUMPTION IN RAT (4) - LMS, Gu 77
(p 954-958)
10. THORN TEST. INDUCING THE HYPOCALCIEMIC TETANY IN RAT. (4) - LMS, Gu 80
(p 1001-1003)
11. GLUCOSE TOLERANS TEST. INSULIN INDUCED HYPOGLYCEMIA IN RAT (4) - LMS,
Gu 79
(p 993-999)
12. CHANGES IN CARDIOVASCULAR SYSTEM INDUCED BY MUSCLE WORK. ASTRAND. EMG (4)-
LMS
Students should come prepared to practicals. Description of each practical is given on the LMS. Also,students should read textbook (Guyton) to get ready for practical. Next to each practical listed above isgiven chapter(s) from textbook that should be studied in advance.
Šalata 3– Departement of Physiology
Lecture room (PL) and practical rooms (PP, PP2)
Lectures will take place in hall: Physiology lecture room (PL) or available lecture room (L) in main building
according to schedule
Seminars will take place in hall: Physiology lecture room (PL) or available lecture room (L) in main building
according to schedule
IV. EXAMINATIONS
IV.a. EXAM POLICY:
Exam questions will include material presented in lecture, assigned chapter readings and case studies distributed duringclass or posted on the course web site. Questions are multiple choice with only one correct answer. Each question accountsfor one point and there are no negative points.
Major colloquium quizzes
Three major colloquium quizzes will be held during the course. These quizzes are named P-1, P-2 and P-3 colloquium. Eachquiz is made up of 60 multiple choice questions equally distributed through textbook obligatory chapters.
Ph1 colloquium - includes general physiology, muscle physiology and the cardiovascularsystem (topics covered in lectures 1-9, seminars 1-11 andpractical work 1-5),Ph2 colloquium - includes physiology of kidney and respiratorysystem (topics covered inlectures 10-13, seminars 12-21 and practical work 6-7),Ph3 colloquium - includes physiology of digestive system, metabolism andendocrinology (topics covered inlectures 14-18,seminars 22-34 and practical work 8-12)
Students are given 90 minutes to complete each colloquium quiz. The score of each colloquium (P1-P3) contributes 33.3% tothe final grade at the end of the course.
IMPORTANT!
The Physiology department strongly encourages students to take and pass the major colloquium quizzes since it gives thestudents a great opportunity to “carry” the passing grades, achieved on each of three colloquium quizzes, from one toanother final exam.
(e.g. if student passed the Ph1 colloquium quiz he/she does not need to retake the Ph1 part of the final exam again duringcurrent academic year 2019./20.)
Bonus points (points earned on the small integration quizzes)
During the course students have obligation to take integration tests. There are six integration tests (after each physiologyfunctional unit there is integration test). Passing these tests gives our students opportunity to earn bonus points. Thebonus points earned during the course will be added to the total score of each of the corresponding colloquium quizzes (P1-P3). The bonus points will be added only if student earned 55% or more of the total score on the corresponding colloquiumquizzes
Final exam
The Final Exam is composed from two parts: written test and oral exam. To qualify for the oral exam student must pass thewritten exam.
Written test is composed of three parts: P1 + P2 + P3. Students are given 90 minutes to complete each test part with30 min break between each part.
Written part of exam has the elimination threshold. Student need to have average score 55% or more on each part of thewritten exam for passing level.
Oral exam is obligatory for the students who earned ≥55% and ≤85% of the total score on the written exam. Studentswho earned 85% and more of the total score on the written exam are exempt from taking oral exam. Oral exam willtake place the day after wrriten part of exam.
The final grade will depend on a grade given at the end of oral exam.
IV.b. GRADING CRITERIA
For passing the colloquiums and exams it is necessary to achieve a positive assessment of written part.
Grades will be determined on the basis of an objective standard of absolute difficulty of the test (called MPR) at:
≥85% of the total score on the test for excellence ,
75% of the total score on the test for very good,
65% of the total score on the test for good,
55% of the total score on the test for satisfactory.
IV.c. EXAM RESULTS:
Exam results will be posted on the Department of Physiology LMS page.
IV.d. ACADEMIC HONESTY
All students are expected to help to maintain an environment of academic honesty. The following behaviors are strictlyforbidden during the administration of the exam: talking, cell phone use, and passing of papers or notes. All backpacks,coats, cell phones, etc. are to be placed in the front of the room.
All students are required to hand-in the packet of exam questions with their name clearly indicated on first page of the exam.It is the responsibility of the student to make sure that the answers he/she wants graded are clearly marked on the scantronsheet with a #2 lead pencil.
B. Types of examination and examination dates
Mandatory written small colloquiums: Integration I 28.01.2020. ; Integration II 07.02.2020.; Integration III 18.02.2020.;integration IV 27.02.2020.; Integration V 11.03.2020.; Integration VI 27.03.2020.
Mandatory written big colloquiums: Colloquium P1 11.02.2020.; Colloquium P2 03.03.2020.; Colloquium P3 31.03.2020.
Eligibility Criteria
The criteria for application to take the final exam are as follows:
For the final exam can apply:
students who attended classes (seminars and practical) regularly,students who passed colloquium (for seminars and practical that were unattended)students who have signature in index for Physiology course
Colloquium for seminars and practical that were not attended is held by teachers who lead the seminar or practical thatstudent did not attend.
The policy for colloquium:
to be able to take colloquium student need to have the colloquium application sheet (student can get it in the roombeside the practicum room)the teacher’s signature in the colloquium application sheet is necessary to confirm that student successfully passedthe colloquium.
To get index signed student must regularly attend classes and pass all colloquiums for classes not attended.
Examination dates
Regular terms Date
Winter
07.04.2020.
16.12.2019.(Final exam for ac. year 2018./19.generation)
Summer
02.07.2020.
14.07.2020.
Autumn
01.09.2020.
15.09.2020.
V./I. LIST OF LECTURERS AND TEACHING STAFF
1. prof. dr. sc. Hrvoje Banfić
2. prof. dr. sc. Dora Višnjić
3. izv. prof. dr. sc. Mirza Žižak
4. izv. prof. dr. sc. Aleksandra Dugandžić
5. izv. prof. dr. sc. Vladiana Crljen
6. izv. prof. dr. sc. Vesna Lukinović Škudar
7. izv. prof. dr. sc. Tomislav Kelava
8. dr. sc. Hrvoje Lalić
9. dr. sc. Alan Šućur
10. dr. sc. Vilma Dembitz
11. dr. sc. Darja Flegar
12. dr. sc. Nikola Habek
13. doc. dr. sc. Marija Renić
14. Barbara Tomić, dr. med.
15. Dino Šisl, dr. med.
V./III UNTENURED LECTURERS:
V./II EXTERNAL ASSOCIATES:
VI. LITERATURE
A. Obligatory
Guyton AC, Hall JE: Textbook Of Medical Physiology, 13th Edition, 2016.
B. Additional
(in alphabetical order):
W. Boron and E. Boulpaep. Medical Physiology 3rd Edition, ISBN: 9781455743773
R.M. Berne and M.N. Levy. Physiology 7th Edition, ISBN:9780323393942
D.R. Bell. Core Concepts in Physiology. Lippincott-Raven, ISBN: 0-316-08868-4
Linda S. Costanzo. Physiology 6th Edition, ISBN: 9780323478816
Chapters from Guyton Textbook for exam:
Ph-1 includes chapters 4, 5, 6, 7, 8, 9, 10, 11, 12, 14, 15, 16, 17, 18, 19, 20, 21, 23 (pages 283-285 untill "Valvular Leasions"), 33,34, 37, 61
Ph-2 includes chapters; 25, 26, 27, 28, 29, 30, 31, 38, 39, 40, 41, 42, 43 (pages 549-551 untill "Pathophysiology of SpecificPulmonary Abnormalities"), 44, 45
Ph-3 includes chapters: 63, 64, 65, 66, 68,69, 70, 71,72, 73, 74,75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85
Reading Assignments:
Students are expected to read the assigned chapters prior to coming to class. The exams will draw heavily upon materialdiscussed during lectures; however, students are still expected to master the material in the assigned chapters
NOTE:
MEF-Learning management System (MEF-LMS)
MEF-LMS is a platform designed to support teaching and learning at School of Medicine University of Zagreb.
MEF-LMS is used for the administration and delivery of the course materials, communication between students andteachers, students’ self assessments
Physiology course materials will be available on the Physiology LMS page
Intellectual Property
We ask you to respect the intellectual property of the authors of the course content. Course materials posted on thephysiology LMS page is copyrighted, by virtue of its publication on the internet, under the Millennium Act.
As such, students are reminded that it is illegal to copy or distribute any of these materials unless it is for personal use, oryou have obtained the consent of the authors of the copyrighted materials.