sensors sensing what matters - ist ag
TRANSCRIPT
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joobst ttechnnoloogiessjobst technologies
BIOSEN
SORS
SENSING WHAT MATTERS
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BIO
Biosensors allow the analysis of complex biological media. The detection of a large number of compounds is of great relevance, not only for scientific research but also for process control in the chemical and food industry. It is also useful in healthcare for the diagnosis, treatment and monitoring of diseases. The pharmaceutical and biotechnology industries greatly desire frequent to continuous analysis of biological media.
In collaboration with Jobst Technologies GmbH, IST AG produces and develops biosensors de-signed to measure the concentration of glucose, lactate, glutamine, pyruvate and glutamate. The biosensors use the enzymatic-amperometric measurement principle. They rely on immobilized enzymes to detect the target analytes with high specificity and reliability. The immobilization system used enables the setting of parameters such as sensitivity and measuring range, thus meeting the requirements of various applications and customers. Furthermore, the technology is compatible with gamma and beta irradiation.
UNIQUE FEATURES OF OUR BIOSENSORS
• Continuous monitoring• Operational stability• Multi-analyte• Biocompatible materials• Micro-miniaturized• Ultra-low flow-rates• Factory calibration• µFluidics integrated• Particle tolerant
• Whole blood / native broth• Repeated drying/wetting• Fast response• Quick hydration• Dry storage• Blank electrode use• Zero-intercept• Almost no interferences• Technological flexibility
Six TransmitterBiosensor transmitter („Six“)Encased with USB 2.0 Digitalinterface.
B.LV5 Biosensor ArrayFlow-through Biosensor B.LV5.Glucose and Lactate electrode.Ruggedized encasement directly connected to Six Transmitter.
Left: B.LV5 Biosensor with rugge-dized encasement, connected to Six Transmitter.
B.IV4 Strip Type BiosensorFor the detection of a single analyte, glucose as standard.
Left: B.IV4 Biosensor connected to Six Transmitter.
Disclaimer: Evaluation product for professionals to be used solely for research and development purposes! Not for medical and diagnostic use. Not to be used for humans. For more information contact IST AG.
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BIO
B.LV5 BIOSENSOR - PERFORMANCE
Biosensor array response to analyte solutionTo demonstrate the independency of the biosensor signals, each type of biosensor was ad-dressed subsequently with its analyte in the concentration, which was used in the mixture.The measurement shown started with a mixture of 5 mM glucose, 2mM lactate, 1 mM gluta-mine, and 0.2 mM glutamate (µM scale on the right side).
B.LV5 BiosensorFlow-through biosensor for multi-parametric measurements (up to four different analytes).
B.LV5 BIOSENSOR - APPLICATION EXAMPLE
The B.LV5 biosensor is used, among other things, for glucose and lactate measurement in intensive care. A specific example is explained below.
EirusTM by MaquetIn this application the B.LV5 biosensor monitors two analytes simultaneously: glucose and lactate. Samples are analyzed every second and data is updated onscreen (at least every minute), numerically and as a trend curve avoiding gaps in the trend.
Accuracy glucose: According to ISO15197-2003, Clarke Error Grid Analysis; 97.7%-99% in area A, 100% in area A+B.
Accuracy lactate: 1609 paired sam-ples were obtained in patients.Correlation coefficient was 91%, Bland-Altman: 0.02 mmol/L3.
Source: http://www.maquet.com/int/products/eirus
Source: http://www.maquet.com/int/products/eirus
Source: Maquet
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BIO
CPP1-180-ZM MICRO PUMP - ENABLING PORTABLE ANALYZERS
We offer reliable, low cost, circular peristaltic micro pumps for applications with low flow rates in the range of 150 nl/min to 180 µl/min.
CPP1-180-ZM Circular Peristaltic Pump
Ultra-small micro pump for fluids and gases.
We additionally offer further peristaltic pumps for differ-ent applications, for example for higher pump rates up to 1 ml/min.
CPP1-180-ZM MICRO PUMP - PERFORMANCE
Graph of the relationship between the pump rate and the applied voltage.
Graph showing the excellent linearity down to a pump rate of only 150 nl/min.
Disclaimer: Evaluation product for professionals to be used solely for research and development purposes! Not for medical and diagnostic use. Not to be used for humans. For more information contact IST AG.
EVALUATION KIT FOR PUMP DRIVERS
Dimensions (LxWxH in mm) 9.5 x 11.2 x 42.7
Weight 5.6 g (without connector)
Flow range 0.15 to 180 µl/min
Operation Bi-directional
Outlet pressure up to 2 bar overpressureZ
Self-priming < -0.9 bar
Typical current 30mA at 3V
Max. voltage ±5V DC
Tube material Silicone (ISO 10993-1, USP class 1-6)
Tube dimension 0.5 mm (inner Ø) / 1.3 mm (outer Ø)
Typical lifetime > 1000 operating hours at 3V
Available connectors JST-SH female, pin-head male or pin-head female
For the peristaltic micropumps are also other flow rates available. For more information visit www.ist-ag.com.
Evaluation kit for pump driversThere are two evaluation kits available to control either 2 to 4 pumps simultaneously. They work plug and play with computers with Windows 10 software. Part of the evaluation kits is an Open Source soft-ware.
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Stegrütistrasse 149642 Ebnat-KappelSWITZERLANDPhone: +41 71 992 01 00Fax: +41 71 992 01 99Email: [email protected]
Engesserstraße 4b79108 Freiburg Im BreisgauGERMANYPhone: +49 761 557 75 20Fax: +49 761 557 75 22Email: [email protected]
INNOVATIVE SENSOR TECHNOLOGY IST AG JOBST TECHNOLOGIES GMBH