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V O L U M E 9

GENES

DEVELOPMENT N U M B E R 11 PAGES 1289--1426 JUNE 1, 1995

EDITORIAL BOARD

J. Adams (Melbourne, Australia) J. Beckwith (Boston, USA) A. Berns {Amsterdam, The Netherlands) E. Blackburn (San Francisco, USA) T. Cech (Boulder, USA) P. Chambon {Strasbourg, France) N.-H. Chua {New York, USA) E. Coen {Norwich, UK) S. Courtneidge (Heidelberg, FRG) R. Evans {La Jolla, USA) G. Fink {Cambridge, USA) P. Goodfellow {Cambridge, UK) S. Gottesman (Bethesda, USA) T. Graf (Heidelberg, FRG) C. Gross {San Francisco, USA) R. Grosschedl {San Francisco, USA) F. Grosveld (Rotterdam, The Netherlands) M. Groudine (Seattle, USA) L. Guarente (Cambridge, USA) R. Harland (Berkeley, USA) E. Harlow (Charlestown, USA) W. Herr (Cold Spring Harbor, USA) J. Hodgkin (Cambridge, UK) R. Horvitz (Cambridge, USA) P. Ingham (London, UK) T. Jessell (New York, USA) N. Jones (London, UK)

Editorial~Production N. Dumser, Technical Editor V. Nicolette, Production Editor L. Olsewski, Editorial Secretary

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Contents GENES & DEVELOPMENT June 1, 1995

Meeting review

Oncogenes: 20 years later Inder M. Verma and Peter K. Vogt and session chairpersons

Thinking about Howard Temin David Baltimore

Cancer: the rise of the genetic paradigm J. Michael Bishop

Research papers

A conjugation-like mechanism for prespore chromosome partitioning during spomlation in Bacillus subtilis Ling Juan Wu, Peter J. Lewis, Rudolf Allmansberger, Philippe M. Hauser, and Jeffery Errington

Distinct modes of cyclin E/cdc2c kinase regulation and S-phase control in mitotic and endoreduplication cycles of Drosophila embryogenesis Karsten Sauer, Jfirgen A. Knoblich, Helena Richardson, and Christian F. Lehner

Regulation of the retinoblastoma protein-related p107 by G1 cyclin complexes Roderick L. Beijersbergen, Leone Carl&, Ron M. Kerkhoven, and Ren6 Bemards

Activation of the TFIID-TFIIA complex with HMG-2 Benjamin M. Shykind, Jaesang Kim, and Phillip A. Sharp

Dissection of progesterone receptor-mediated chromatin remodeling and transcriptional activation in vivo Joe S. Mymryk and Trevor K. Archer

Pip, a novel IRF family member, is a lymphoid-specific, PU.l-dependent transcriptional activator Charles F. Eisenbeis, Harinder Singh, and Ursula Storb

Inactivation of the myogenic bHLH gene MRF4 results in up-regulation of myogenin and rib anomalies Wei Zhang, Richard R. Behringer, and Eric N. Olson

Overexpression of the arginine-rich carboxy-terminal region of U1 snRNP 70K inhibits both splicing and nucleocytoplasmic transport of mRNA Joelle M.-J. Romac and Jack D. Keene

Exonucleolytic processing of small nucleolar RNAs from pre-mRNA introns Tam~s Kiss and Witold Filipowicz

Product news

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Cover Septation and DNA partitioning in spomlating B. subtilis cells. {Top two panelsl Wild-type strain SG38; (bottom two panels) spoHG mutant strain 901. (For details, see Wu et al., p. 1316.)