should there be air there? elizabeth m. regan november 22, 2013 dr. cameron; dr. p.smith, dr....

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Should there be air there? Elizabeth M. Regan November 22, 2013 Dr. Cameron; Dr. P.Smith, Dr. Ebersole

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Page 1: Should there be air there? Elizabeth M. Regan November 22, 2013 Dr. Cameron; Dr. P.Smith, Dr. Ebersole

Should there be air there?

Elizabeth M. Regan

November 22, 2013

Dr. Cameron; Dr. P.Smith, Dr. Ebersole

Page 2: Should there be air there? Elizabeth M. Regan November 22, 2013 Dr. Cameron; Dr. P.Smith, Dr. Ebersole

• CC: abdominal pain, N/V, T101.3• HPI: Patient is a 42 y/o female who originally presented to the

ED on 10/26 with 1 month history of cough and markedly elevated WBC of 200. Patient was diagnosed with ALL and admitted for workup and initiation of chemotherapy. Her hospital stay became complicated by an UE DVT, large left-sided pleural effusion and retroperitoneal hematoma s/p BM biopsy. On 11/11 patient developed mid-epigastric abdominal pain, N/V and became febrile to 101.3 F.

• PMH: HTN, UE DVT, left-sided pleural effusion, hematoma• PSH: nill• Allergies: NKA• Social: never smoker, denies alcohol and drug use

CASE: OS (MR:6605248)

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Page 3: Should there be air there? Elizabeth M. Regan November 22, 2013 Dr. Cameron; Dr. P.Smith, Dr. Ebersole

• Physical Exam:– Vitals: T99.3, BP 136/70, HR 112, RR 20, O2 97%– CONSTITUTIONAL: NAD– LUNGS: CTAB  – CARDIOVASCULAR: NSR normal S1 and S2, no S3 or S4, no

murmur– ABDOMEN: Normal bowel sounds, soft, mildly distended, TTP over

epigastric and RUQ  – EXTREMITIES: no LE edema, Left upper extremity - no longer

edematous surrounding PICC, not TTP– NEURO: A&Ox3, CNII-XII grossly intact  – SKIN: no rashes

• Labs:– Neutropenic– Normal lactate

CASE

Page 4: Should there be air there? Elizabeth M. Regan November 22, 2013 Dr. Cameron; Dr. P.Smith, Dr. Ebersole

• Acute Abdominal Pain, Fever– Ulcer– Pancreatitis– Infectious (Viral, Abscess)– Biliary Obstruction (cholecystitis, cholangitis, malignancy)– Tumor Lysis

• Imaging Modalities to consider– Ultrasound vs CT vs MRI?– Contrast?– Decision: CT abdomen and pelvis with IV contrast

Working Clinical Diagnoses

Page 5: Should there be air there? Elizabeth M. Regan November 22, 2013 Dr. Cameron; Dr. P.Smith, Dr. Ebersole

Appropriateness Criteria

Page 6: Should there be air there? Elizabeth M. Regan November 22, 2013 Dr. Cameron; Dr. P.Smith, Dr. Ebersole

Normal CT Abdomen (Level of Stomach)

Axial CT (with PO contrast)

Page 7: Should there be air there? Elizabeth M. Regan November 22, 2013 Dr. Cameron; Dr. P.Smith, Dr. Ebersole

OS CT Abdomen (Stomach)

Page 8: Should there be air there? Elizabeth M. Regan November 22, 2013 Dr. Cameron; Dr. P.Smith, Dr. Ebersole

CT Abdomen (Small Bowel)

Page 9: Should there be air there? Elizabeth M. Regan November 22, 2013 Dr. Cameron; Dr. P.Smith, Dr. Ebersole

CT Abdomen (Small Bowel)

Page 10: Should there be air there? Elizabeth M. Regan November 22, 2013 Dr. Cameron; Dr. P.Smith, Dr. Ebersole

CT Abdomen (Small Bowel)

Page 11: Should there be air there? Elizabeth M. Regan November 22, 2013 Dr. Cameron; Dr. P.Smith, Dr. Ebersole

• Pneumatosis intestinalis seen in posterior gastric wall, small bowel, as well as air within draining gastric vein

• What’s next?– Investigate for pneumoperitoneum

Page 12: Should there be air there? Elizabeth M. Regan November 22, 2013 Dr. Cameron; Dr. P.Smith, Dr. Ebersole

OS KUB- 1 view

Page 13: Should there be air there? Elizabeth M. Regan November 22, 2013 Dr. Cameron; Dr. P.Smith, Dr. Ebersole

OS CXR-No pneumoperitoneum

Page 14: Should there be air there? Elizabeth M. Regan November 22, 2013 Dr. Cameron; Dr. P.Smith, Dr. Ebersole

Abnormal CXR: Free Air under Diaphragm

Page 15: Should there be air there? Elizabeth M. Regan November 22, 2013 Dr. Cameron; Dr. P.Smith, Dr. Ebersole

• Pneumatosis Intestinalis– Gas within the wall of the bowel; Can occur anywhere

between esophagus and rectum– Symptom of multiple disease states, both GI and non-GI

related– Can be benign or an emergency • Emergencies include pneumoperitoneum, bowel

ischemia/infarction • Most presentations are benign; most patients are

actually asymptomatic– Most Common in adults ages 40-70 as well as in the

neonate population (associated with Necrotizing enterocolitis). Equal prevalence in males and females

Working Diagnosis/ Pathology

Page 16: Should there be air there? Elizabeth M. Regan November 22, 2013 Dr. Cameron; Dr. P.Smith, Dr. Ebersole

– Most commonly associated disease states:• COPD• Immunocompromised states• Inflammatory or infectious causes of GI tract• Recent surgical or endoscopic procedures• Diabetes• Ischemia

– Clinical Presentation usually includes: N/V, abdominal pain, mucus or blood in stools, weight loss

Page 17: Should there be air there? Elizabeth M. Regan November 22, 2013 Dr. Cameron; Dr. P.Smith, Dr. Ebersole

• Plain Films:– Intramural gas can be linear, curvilinear, or circular in

appearance– Linear pneumatosis tends to be more ominous, but can be

benign– If pneumoperiotoneum is also present, look for: free air

under the diaphragm, Rigler’s sign, falciform ligament sign• CT:– More sensitive– Circumferential collections of air adjacent to lumen of

bowel

Characteristic Findings

Page 18: Should there be air there? Elizabeth M. Regan November 22, 2013 Dr. Cameron; Dr. P.Smith, Dr. Ebersole

• Patient was non-peritonitic, complaining only of mild pain

• No pneumoperitoneum• Surgery consulted, no evidence for bowel

infarction/ischemia• Serial abdominal exams, prontonix, and fluid

resuscitation• Patient improved within 36 hours. No surgical

intervention needed.

Outcome/Treatment