shunt malfunction. classification of shunt malfunction mechanism mechanical vs functional time of...
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Shunt malfunctionShunt malfunctionShunt malfunctionShunt malfunction
Classification of shunt malfunction
Mechanism
Mechanical vs Functional
Time of occurrence
Early vs Late
Site of malfunction
Causes of malfunction
Surgeon, Patient, Shunt
Oregon H S U(275 cases)
Toronto-Paris(1552 cases)
Denmark(884 cases)
P = posterior(60 cases)A = anterior(61 cases)
Chicago prospective study
Shunt Survival Function
DURATION
6 5 4 3210
Cum Survival
1.0
.9
.8
.7
.6
.5
.4
P
A
B & W plots - Follow-up/Event
DP Shunts (Toronto-Paris) - First insertion
Underdrainage
"Overdrainage"
Improper placement
Migration
Fracture
Obstruction XX
Follow-up
211568284288334N =
2800
2400
2000
1600
1200
800
400
0
Causes of shunt complications
Early shunt complications
Surgical technique
• Improper placement
• Disconnection
• Migration
• Skin problems
Debris in the CSF
• Early Obstructions
Shunt
• Acute overdrainage
Causes of shunt complications
Late shunt complications
Chronic overdrainage
• Hydrodynamic characteristics
Mechanical stress on the device
• Connectors
• Deterioration of the distal tubingMigration & fracture
Proximal obstruction
Delayed Proximal obstruction is Delayed Proximal obstruction is correlated with chronic overdrainagecorrelated with chronic overdrainage
Slit Normal Enlarged
None 55.7 78.3 63.9
S. Failure 44.344.3 21.7 36.1
Ventr. Obstr. 81.381.3 8.1 21.4
Consequences of overdrainage
Rare : « slit ventricle syndrome » Epstein 1980
Very common : proximal obstruction
« Slit ventricle syndrome »
Recurrent episodes of ICH despite a patent shunt
Rare > 0.5% (10/3000)
Loss of volumetric buffering reserve
Treatment
Increase the valve resistance
Cranial expansion
Proximal obstruction
Very frequent
ICH with small ventricles at the
beginning (Laplace’s law)
Shunt revision
Equivalence
Hypothetically….Prevention of late shunt malfunction by :
Prevention of deterioration of the distal
tubing
Prevention of chronic overdrainage
Prevention of deterioration of the distal tubing
Integral distal tubing - no
connectors
Striped distal tubing
The silent revolution
Past
Present
Hypothetically….Prevention of early shunt malfunction by :
?
Answer :Series of 946 new cases of hydrocephalus in
childhood (1987-2002)
15 years of hydrocephalus treatment at Necker
Thanks to Ricardo and Mercia
Series characteristics
Age
Median 184 day
Etiologies
Type of first treatment
Third V. - results
Success 66.5%
Factors correlated with success (Cox)
Variable in the equation : ETIOLOGY
• Tumors 84%
• Meningitis 20%
Not in the equation : SURGEON,
PATIENT’S AGE
Survival Function - Third ventriculostomy
Follow-up
3600
3240
2880
2520
2160
1800
1440
1080
720
360
0
Cum
Sur
viva
l1.0
.9
.8
.7
.6
.5
.4
.3
.2
.10.0
First shunt characteristics - all OSV -- all OSV -
Type
VP / VA 667 / 1
Right / Left 579 / 88 1 bilateral
Tip location
Correct 580
Questionable 88
“questionable” placement
Shunts - results
No complications 411 61.5%
Infection 49 7.3%
Mechanical complic. 208 31.1%
Survival Function - valve OSV
Follow-up
5400
5040
4680
4320
3960
3600
3240
2880
2520
2160
1800
1440
1080
720
360
0
Cum
Sur
viva
l
1.0
.9
.8
.7
.6
.5
.4
.3
.2
.1
0.0
50% at 12 yrs
=
2.5 M$ saved
Probability of survival 45.9% at 15 years
Follow-up
Cum
Sur
viva
l
4320
3960
3600
3240
2880
2520
2160
1800
1440
1080
720
360
0
1.0
.9
.8
.7
.6
.5
.4
.3
.2
.1
0.0
Survival Function - OSV vs. « DP shunts »
Log Rank 0.000
OSV
DP shunts
Dramatic decrease of late shunt complications,Dramatic decrease of late shunt complications,but number of early complications unchanged !but number of early complications unchanged !
Prevention of early shunt complications ?
Complication types
Follow-up
5400
5040
4680
4320
3960
3600
3240
2880
2520
2160
1800
1440
1080
720
360
0
Cum
Sur
viva
l1.0
.8
.6
.4
.2
0.0
Survival Functions - Ventricular tip location (correct vs questionable)
« correct »
« questionable »
From the Necker collectionFrom the Necker collection
“Z”
“Signature”
“Almost”
“Toreador”
“Down”
“More down”
“Up”
“More up”
“The lost ventricles”
“Subway”
Conclusions
Third ventriculostomy in 30% of the cases
Prevention of late shunt complications have been achieved by
limiting chronic overdrainage
using integral, “striped” distal tubing
Prevention of early shunt complications is largely up to us
Good surgical technique
Clean CSF
Appropriate hydrodynamic characteristics of the valve