What our eyes need most?

Essential nutrientsfor our healthy sight

What are the major essential vitamins & minerals for

healthy eyes?

Vitamin C Vitamin E Lutein Copper Zinc

How Vitamin C helps for our healthy sight?

Vitamin C is a nutrition vital for the production of aqueous humor & the reformation of corneas.

Acts as antioxidant which inactivates free radicals in ocular tissues.

A long term Vitamin C supplement use (10+ years) has been associated with reduced risk of cataract.

How Vitamin E helps for our healthy sight?

Vitamin E is a potent antioxidant that helps to reduce free radicals in the retina and supports in the circulation and tissue health.

Vitamin E helps to protect against cataract, AMD and improves visual clarity.

High serum Vitamin E concentrations have been associated with reduced risk of cataract.

How Lutein helps for ourhealthy sight?

Lutein is a subgroup of the carotenoid family that acts as a filter for the light sensitive photoreceptor cells in the macula of the eyes.

High levels of dietary Lutein is associated with relatively lower risk of AMD.

How Copper helps for our healthy sight?

Copper supports the formation of strong flexible connective tissues for proper eye structure and plays important role in growth, skeletal integrity, and development of nervous system.

As a part of various enzymes, it takes part in numerous metabolic conversions.

How Zinc helps for ourhealthy sight?

Zinc catalyst the conversion process of Vitamin A to its active form retinaldehyde in retina

Zinc is an essential trace element involved in many enzymes system.

What will happen if we are not taking sufficient

amount of essential vitamins & minerals?

We will suffer various types of Age Related Eye Diseases (ARED) like-

Age Related Macular Degeneration (ARMD) Cataract

What is Age-related Macular Degenaration?

Macular degeneration, often age-related macular degeneration (AMD or ARMD), is a medical condition that usually affects older adults and results in a loss of vision in the center of the visual field (the macula) because of damage to the retina.

What are the symptoms & causes of AMD?

Symptoms: Drusen, Pigmentary changes, Blurred vision

Causes: Aging, Family history, Macular degeneration gene, Drusen, Cholesterol, Obesity, Hypertension, Exposure of sunlight, Vitamin D deficiency, Smoking, Oxidative stress

What are the types of AMD?

Dry AMD: Dry AMD is a chronic eye disease that causes vision loss in the center of your field of vision. Dry macular degeneration is marked by weakening of the macula, which is in the center of the retina.

Wet AMD: Wet AMD (more advanced type of AMD) is a chronic eye disease that causes vision loss in the center of your field of vision. Wet AMD is generally caused by abnormal blood vessels that leak fluid or blood into the region of the macula.

Alarming facts about AMD

50% of people >50 years of age have AMD. 2/3 of 90 years of age have AMD. 80-90% suffer in Dry AMD & 10-15% suffer in

Wet AMD among all AMD patients. 90% of all cases of severe vision loss from the

disease.

Treatment options for AMD

Anti-angiogenic drugs Laser therapy Photodynamic laser therapy Vitamins: Vitamin C, Vitamin E, Beta-carotene,

Zinc, Copper can decrease the risk of vision loss in patients with intermediate to advanced AMD

Effects of Antioxidant Vitamin-Mineral in AMD

Reduces risk of Advanced AMD

25%

68%

Reduces risk of Early AMD

What is Cataract?

A cataract is a clouding of the lens of the eye that can impair vision.

Risk Factors: (a) Non-modifiable: Age, Family history, Generics (b) Modifiable: Radiation/light exposure, Diabetes, Smoking, Alcohol

What are the types of Cataract?

Types of cataract regarding position: Nuclear cataract: A nuclear cataract forms deep in the

central zone (nucleus) of the lens. Nuclear cataracts usually are associated with aging.

Cortical cataract: A cortical cataract starts in the edge/outer part of the lens. This type of cataract occurs in the lens cortex, which is the part of the lens that surrounds the central nucleus.

Alarming facts about Cataract

50% of people over 75 years of age suffer from cataract in western world

90% of cataract create vision impairment and blindness are found in developing countries

Developing world wide much higher

Treatment options for Cataract

Surgery is the only option if cataract is established intra ocular lens (IOL) implantation

Preventive options are: Vitamin C, Vitamin E, Lutein, Beta-carotene, Omega-3 fats, Proteins, Fibre, Niacin, Riboflavin, Thiamine, Folate, Vitamin B12

Effects of Antioxidant Vitamin-Mineral in

Cataract

Reduces risk of

Nuclear Cataract

20% - 43%

23% - 30%

16% - 60%

Reduces risk of Cortical Cataract

Reduces risk of

Any Cataract

It is our great pleasure to inform you that, Opso Saline

introduces,

Antioxidant Vitamin-Mineral Capsule

Sigvit®

VITamins for healthy SIGht

Keeps your eyes healthy

Vitamin C Vitamin E Lutein Copper Zinc

60 mg 30 mg 6 mg 2 mg 15 mg

Product Presentation & Price

Pack Price (MRP)

1 Capsule 8.03 /=

6 x 5 240.90 /=

How we will take Sigvit® capsule?

One capsule, one or two times daily after meal or as directed by the physician.

Is Sigvit® safe for special groupof patients?

Generally vitamin & mineral medications are safe in pregnancy but it is recommended to consult with physician before using.

Market Analysis of Eye Vitamins

SL ProductName Company Pack

SizeMRP(BDT)

Value Sales/Year (cr)

Unit Sales/Month Gr (%)

01. I-GOLD Aristopharma 30s 240 2.48 8,622 15.9402. AZECOL Incepta 28s 224 1.95 6,788 -5.2503. OPTAVIT Popular 28s 224 1.62 5,637 -11.5504. EYEVI Square 30s 240 1.20 4,192 19.1605. VIVIS Beximco 30s 300 0.89 3,102 -16.0906. OCUVIT Asiatic 24s 192 07. TIOXIL ACI 30s 240

IMS-4th Quarter-2014

MD. HASIF SINHAProduct Executive, PMD, Opso Saline Ltd

01755536494