size optimization of yag _ final
TRANSCRIPT
Alejandro Cota
http://www.mesotheliomaguide.com/wp-content/uploads/2014/05/PhotodynamicTherapy.png
Procedure:
• Intravenous insertion of
anticancer nano-drug
• Irradiate the tumor site
• Drug is released and the
tumor is targeted
Scintillator Ionizing
radiation Photo-
luminescence
Source: http://www.uspharmacist.com/content/s/197/c/33020/
• Larger than 10 nm
to avoid first-pass
elimination in the
kidney
• Smaller than 150 to
200 nm to avoid
clearance in the
liver and spleen
YAG:Pr
Alumina
Praseodymium
Yttrium
Methanol
Mix until solvent evaporates.
0
200
400
600
800
1000
1200
0 1 2 3 4 5 6 7
Tem
pera
ture
°C
Calcination Profiles
Time (hours)
~ 2 days
Filters
White: 450nm
Yellow: 450nm
Green: 220nm
Blue: 200nm
Filters
White: 450nm
Green: 220nm
Filters
Yellow: 450nm
Green: 220nm
Scale:100nm
Pictures taken by:
Dr. Novitskaya
Scale: 50nm
Pictures taken by:
Dr. Novitskaya
YAG:Pr
Aluminum
Praseodymium Yttrium
Carbohydrazide Fuel
Water
Combust at T = 500 °C
0
200
400
600
800
1000
1200
0 1 2 3 4 5 6 7
Tem
pera
ture
°C
Calcination Profiles
Time (hours)
~50 min
Sol-Gel Synthesis
Combustion Synthesis
Impurities
2ϴ
Pictures taken by: Dr. Novitskaya
Scale: 100nm
Pictures taken by: Ajay Sapre
Pictures taken by:
Dr. Novitskaya