Planning for INBRE II – The Renewal

External Advisory Board Meeting12-13 February 2009

Renewal - Strengths

• INBRE-I has initiated a network linking the three main partners (UNR, UNLV, NVCI).

• The Biomedical Pipeline functions smoothly and is enormously satisfying.

• Research service cores.

• The Administrative Core has a good understanding of how to manage the INBRE.

• Interactions with COBRE projects are increasing.

• Mentoring and faculty development is improving.

Renewal - Challenges

• The state lacks a strategic plan for biomedical sciences.

• The new biomedical institutions are private and developing bilateral partnerships: NVCI, Rouvo Brain Institute, Whittemore-Peterson Institute, Touro University College of Osteopathic Medicine (Nevada’s largest medical school). Where does INBRE fit in?

• Many of the “senior administrators” at UNR, UNSOM, and UNLV are new and interim

• The state’s fiscal situation is dire

• Much action and growth in the south (UNLV, NVCI, Rouvo, Touro)

Renewal - Opportunities

• This is the time to change programs that are less rewarding

– Basic Science Research

• We have a medical school

– Clinical faculty as researchers and collaborators– MD / PhD– Resident research experience– Fellowship programs

• We have untapped areas

– K-12– NIH Science Education Partnership Awards (SEPA)

Renewal - Opportunities

• We have untapped partners (if I can figure out how to work with them). – Development of research at TMCC, CSN, GBC– CTSA at UC Davis– UNR College of Agriculture, Biotechnology and Natural

Resources (CABNR)– Nevada State College– Rouvo Brain Institute– Whittemore-Peterson Institute– Touro University College of Osteopathic Medicine

Renewal Plans:Outreach

Draft Renewal – Biomedical Students Pipeline Program Expansion

• Expand INBRE undergraduate outreach and create K-12 program.

– We are partnering with TMCC to embed research in community colleges. (Curriculum development)

– We are partnering with Dr. Julie Ellsworth to submit a SEPA award spring 2009. In year 5 we are piloting 4 middle school science coaches.

Basic Science Pipeline Current ProposedUndergrad summer research (UROP) program at UNR, UNLV, NVCI $78,000 $78,000

Biomedical Students Pipeline $218,000 $228,900

Research at Community Colleges $0 ?

K-12 Science Coaches $10,000 $32,000

Community College Research

• The goal is enhanced biomedical science instruction and experience at community colleges.

– Incorporate “Real Science” into existing biology, chemistry, and physics labs.

• Developed following a workshop in Seattle presented by the Council for Undergraduate Research

Dr. Julie Ellsworth, Dr. Dan Lorenz, Dr. Laura Briggs, TMCCDr. James Kenyon, INBRE

• Ideas presented to Dr. Jowel Laguerre VP for Academic Affairs at TMCC.

• Partership with Chris Fritsen (NV NASA Space Grant Consortium Director).

SEPA

• K-5 Level (Elementary School) – The “Music Teacher” Model

– Teachers with previous training in science to be roving teachers for science at multiple elementary schools.

– Renovate existing school space to provide bench and storage space.

• 6th-8th Grades (Middle School) and 9th-12th (High School) – Science Coach Model

– Out-of-classroom Science Coaches (paid like athletic coaches) who will run science clubs and mentor students working on science fair projects.

Renewal Plans:Cores

Draft Renewal - Cores

• Continue current support of research service cores.

Cores Current Proposed

Bioinformatics North $253,000 $240,000

Bioinformatics South $85,000 $60,000

Proteomics $262,000 $260,000

Cytometry $25,000 $25,000

Live Animal Imaging - -

UNLV Central Core $170,000 $200,000

Renewal Plans:Research Projects

Draft Renewal – Faculty Research Projects

• Fund one early career basic scientist at each partner institution. New hires at UNR and UNLV.

Basic Science Faculty Current Proposed

UNR $351,000 $125,000

UNLV $216,000 $125,000

NVCI $243,000 $125,000

Draft Renewal – Develop Clinical Pipeline

• Create new Clinical Pipeline with funds previously directed to Basic Science.

Clinical Pipeline Current Proposed

MD/PhD Stipends $0 $60,000

Residents (Yr 5 pilot program) $50,000 $50,000

Clinical Faculty (Yr 5 pilot program) $30,000 $150,000

Clinical Pipeline

• MD/PhD – The PI is working with the UNSOM Senior Associate Dean for Research to provide stipends for two MD / PhD students to work in outstanding (funded) basic science labs in Nevada.

• Resident Research Experience – The PI is working with the UNSOM Associate Dean for Graduate Medical Education to develop a program that will put Nevada Residents into outstanding (funded) basic science labs in Nevada. The current plan is for a 3 month experience.

• Clinical Faculty Research – The PI is working with the Dean of the School of Medicine and Vice President of the Division of Health Sciences to develop an RFA for a clinical / translational science project. The goal is to enable a clinical faculty member of UNSOM to initiate a project that will ultimately be funded independently.

Clinical Pipeline – Pilot Programs in Year 5

• $50K for resident research experience

• $30K for a genome-wide association study using single nucleotide polymorphisms.

– Dr. Karen Schlauch and the INBRE Administrative Core put out an RFA circulated to the partner institutions and the School of Medicine for a preliminary, proof-of-concept project that will lead to a comprehensive experimental study fundable by the NIH.

Draft Renewal - Community Based Participatory Research Core (CBPR)

• We are investigating the possibility of a new Community Based Participatory Research Core.– Increase INBRE activity in clinical / translational– Engage faculty and programs in UNLV School of Public Health,

UNR Division of Health Sciences, Touro University College of Osteopathic Medicine.

Current Proposed

CBPR $0 $100,000

Thank you