For The Clinicians SWAN-iCare Offers

Remotely monitor the wound healing process without patient attending a clinic. Provide both wound diagnostic and treatment in a single device for diabetic foot ulcers (DFU) and venous leg ulcers (VLU). Access of real time quantitative data to monitor wound healing. Earlier identify potential infection in order to minimise cost and risk to patient safety.

SMART WEARABLE AND AUTONOMOUS NEGATIVE PRESSURE DEVICE FOR WOUND MONITORING AND THERAPY

SWAN-iCare is an ambitious project which will provide a major leap forward in the management of chronic wounds, mainly diabetic foot ulcers (DFU) and venous leg ulcers (VLU).

Venous Leg Ulcers

Painful high exuding ulcersTreatment - time consuming and expensive 3-5% of over 65 years olds will suffer with a VLU during there life time Up to 50% of VLU are open and unhealed for 9 months

For The Patients SWAN-iCare Offers

Personalised treatment to meet their individual needs.Improves their quality of life with the reassurance that their condition is be being remotely monitored.Reduce their dependency on clinical visits.Increased lifestyle flexibility

Diabetic Foot Ulcers

Painful low exuding ulcersCan result in possible amputation or morbidityUp to 4% of those with diabetes will develop a foot ulcer annually

SWAN-iCare represents the next generation integrated autonomous solution for monitoring and adapting personalized therapy of foot and leg ulcers. At the core of the project is the fabrication of a conceptually new wearable negative pressure device equipped with capability of remote monitoring via wireless technology (ICT).

Patient Continuous efficient monitoring of wound parameters at the patients home.Personalised and improved therapy initiated by the physician remotely and adapted to the daily measurements.Faster wound healing due to the early identification and therapy of potential problems. Wound deterioration can be identified early and acted upon, therefore leading to reduced morbidity and amputation rates.Reduced need for hospitalisation, better quality of life with better mobility, more comfort and less stress.

Society and HealthcareReduced need for hospitalisation, results in reduced healthcare costs, and better therapy for an increased remotely monitored number of patients. Less losses due to patient remaining away from work. Less burden over the relatives and carers who may help and support the patient. Better care for patients living in remote geographical places. Lower nursing involvement allows for more patients’ treatments. More intelligent and effective prescription leading to faster wound healing, thus lower healthcare costs.

Medical ScienceNew ways of patient monitoring by correlating continuous measurements not available before. Continuous objective measurement contributing to evaluation of wound progress, and treatment effectiveness.New remote therapeutic approaches with innovative products. New potential for research by correlating measurements and outcomes of multiple patients when these become available in the future.

ICT Science and BusinessNovel solutions incorporating multidisciplinary research providing services of unparalleled quality. Fresh business models in the wound management market and closer business relationships between the various disciplines and between the players of the potential value chain in the wound management market .Reinforced leadership and innovation in the area of convergence of Bio-micro-ICT system, gained by knowledge and skills and improving the competitiveness of the involved industries .

Wireless Wide Area Network(GSM,GPRS,UMTS)

Wireless Local Area Network(WIFI)

Healthcare NetworkHospital InfrastructureDoctors, Care Centre, etc.

Smartphone (User interface / Gateway)GUI applicationRemote control and monitoring of the SNPDCameraGatewayBluetooth, WFI, Edge : GSM/GPRS: UMTS

Wearable sensors extracted parametersInsole pressure on three pointsDorsiflexion parameters

External devices extracted parametersBody temperatureGlucose levelSPO2 values

OximeterMeasuring on finger and toe

Glucose meterMeasuring range 20~630mg/dLDate transfer / communication: wireless

Ear ThermometerMeasuring Core Body Temperature

Smart Negative Pressure DeviceWound Exudate parametersLocal skin and wound temperatureMMP’s (1,2,3,8,9)TNFaCRPpHBacteriaActuator controlPumpPhysical SensorPressure sensorInside parameters extractionActivity classificationEmbedded electronicsAnalogue front-end sensor interfaceLow Power microcontrollerPower managementMicrocontrollerUltra low power communication moduleUSBSD Memory CardUser interface

Smart Disposable interface partsWound surfaceRelease of collagenRelease of growth factorsRelease of MMP inhibitorsBiosensing optical fibreColometric sensorsFlat wound drainTransparent occlusive dressingNegative pressure capabilityPhysical sensorsTemperature sensorConductive sensor

Wearable sensorsPulse Oximetry opto-electronic sensorInsole pressure sensorDorsiflexion sensor

Pathway to improvement

Current typical clinical workflow for a patient with a diabetic foot ulcer.

Clinical workflow for a patient with a diabetic foot ulcer after the introduction of the SWAN-iCare.

SWAN-iCare System Design The SWAN-iCare system will allow the physicians to be continuously

aware of patient’s condition remotely and to receive warnings highlighting situations requiring instant actions and emergencies. In this way, the loop of diagnosis, processing and feed back to therapy will be closed. The SWAN-iCare system has three different ICT applications:

• The embedded application within the Negative Pressure Device, which will be responsible for the local sensor data fusion. Data fusion will be the basis for any local warnings sent to the patient’s personal station (smart-phone or similar) as well as for communicating the regular measurements to the smart=phone and medical staff gateway application.

• The smart-phone application which will allow for local data processing of sensors for the patient’s information as well running all device management processes, including the remote configuration of the therapy (actuators start and stop, medication frequency or refuel, etc.)

• The medical staff gateway application which will provide innovative, efficient data processing rules, combining the patient’s conditions and pathology with the actual monitoring data, comparing with clinical workflows and thus alerting when an emergency occurs. This application will also incorporate novel and user friendly interfaces to visualise with the measured data over time and correlate measurements when necessary.

Back

-end

SW

AN

iCar

e Ap

plic

atio

ns

Patient’s Personal Station

Application

Patient

Administrator

Doctor / Clinician

Smartphone

Clinical Workflows / User Databases

Internet

Administration and Management

Clinical Analysis and SWAN iCare eHealth

RecordsSensor Data

Events / Emergency Alerts SNPD Status

Back-end SWAN iCare

Medical Gateway

SWAN iCare SNPD

On body Sensors

Hospital

HomeExternal Medical Devices

Embedded Software

Wireless Connection

WP2Clinical and

End-user Requirements

WP8Verification and Clinical Validation

WP3Complete

System Design

WP7System

integration and

prototyping

WP9 Dissemination and Exploitation

WP1 Management

WP4Development and / or selection of micro-sensors and micro -actuators

WP5Electronics and wireless connectivity

components

WP6Embedded software and medical applications

Work Programme Objective: Smart Components and Smart Systems Integration (b) Micro-Nano Bio-Systems Total budget: 8.079.179 € Funding: 6.113.999 €Call identifier: FP7-ICT-20011-8 Time Scale 2012-2016

Heamopharm Biofluids European Wound Management Association Secretariat Institute of Communications and Computer Systems Smith & Nephew SWISSINNOV

EXUS S.A. (Coordinator), GreeceCommissariat à l’Energie Atomique et aux Energies AlternativesCSEM SA Università di Pisa CHU Grenoble Euroresearch

Consortium Members:

This research is supported by the European Commission under the 7th Framework Programme. Project No 317894