smartphone-powered ophthalmic diagnostics
TRANSCRIPT
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SMARTphone OPHTHALMIC DIAGNOSTICSStartups and optical designs
Petteri Teikari, PhDhttp://petteri-teikari.com/
version Thu 22 September 2016
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Smartphone fundus cameras #1
http://www.odocs-tech.com/
http://www.peekvision.org/
d-eyecare.com
ophthalmicdocs.com
OPEN-SOURCE COMMUNITY
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Smartphone fundus cameras #2
volk.com
medisave.co.uk
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PORTABLE/SMARTPHONE fundus cameras #3Why would you need someone else to take a picture of your own eye?
http://web.media.mit.edu/~tswedish/projects/eyeSelfie.html
http://www.optomed.com/
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OPHTHALMOLOGICAL OPTICS
A The human eye as an optical system (Sliney 2005) - estimates of human eye focal length f
vary between 17-24 mm, see e.g.hypertextbook.com (f = 22.3 mm standardized result)
B Photoreceptor optics (Warrant and Nilsson 1998)
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SMARTPHONE SENSOR&OPTICS
anandtech.com
dpreview.com
anandtech.com
“Easiest to design to iPhones as the optomechanics are the same, whereas with different Android phones, the optics should be customized to each model”
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OPTICAL DESIGNS #1
Giardini et al. (2014)[PDF]
Fang et al. (2015)
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OPTICAL DESIGNS #2
Exploded view of the D-Eye module (angles and distances between components are approximated). Retinal images are acquired using coaxial illumination and imaging paths thanks to a beam splitter (C). The blue arrow depicts the path of the light; red arrow depicts the path of fundus imaging. Device components are glass platelet (A) with imprinted negative lens (A )′ , photo-absorbing wall (B), beam splitter (C), mirror (D), plastic case (E), diaphragm (F), polarized filters (G, H), flash and camera glass (J, I), and magnetic external ring (K). Russo et al. (2015)
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OPTICAL DESIGNS #3
http://web.media.mit.edu/~tswedish/projects/eyeSelfie.html
“The subject aligns his/her own for optimal image”
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OPTICAL DESIGNS #5
3ders.org
ophthalmicdocs.com
3D print your own parts, or have them printed for you at Shapeways
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OPTICAL DESIGNS #6https://hackaday.io/project/11943-open-indirect-ophthalmoscope
Including CAD files for 3D Printingg and Eagle files for the PCB design
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Medical optics Small-scale micro-optics
http://nanocomp.fi/what-we-do/applications/healthcare/
https://www.luxexcel.com/portfolio/microstructures-micro-optics/3D printed custom microstructures and micro optics, LUXeXceL
http://dx.doi.org/10.1038/nphoton.2016.121 Two-photon direct laser writing of ultracompact multi-lens objectives