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Souvik Dey, e-mail id: [email protected] Page 1 SOUVIK DEY Address: Plot B, Gitanjali, Jheelbagan, 24 PGS (N), P.O.Hatiara, Kolkata-700157, WB, India. Contacts: (+001)3303892332 (USA) / (+91) 8013185609 Email ID: [email protected] CAREER OBJECTIVES Seeking a permanent position to utilize my abilities, technical skills and experience in the area of research and development in life science/pharmaceutical industry while being resourceful, innovative and flexible; I believe all these aspects will be helpful to deal with the challenges of the industry, productively. EXPERIENCE 2015 (November) present: Working as a Post-doctoral Research Associate in the Department of Biological Sciences, Kent State University, Ohio, USA. Here my goal is to identify substrates of Protein kinase A and binding partners of Glycogen synthase kinase 3 using proteomics and molecular biological techniques in knock-out/transgenic mice models. 2010 (November) 2015 (November): Worked as a Doctoral research scholar. Successfully completed a DBT, GOI funded 4-year R&D project as a research scholar in the Centre for Rural & Cryogenic Technologies, Jadavpur University on purification, characterization, hormonal regulation and signal transduction mechanism of certain serum glycoprotein related to treatment of male infertility. 2009 (January) - 2010 (November): Experience of research in cancer immunology as Junior Research Fellow in Chittaranjan National Cancer Institute (CNCI), Kolkata. 2008 (July) & 2014 (August): Training in the GLP/GMP grade Quality Control (Microbiology/Chemistry) laboratory in Pharmaceutical industry (viz. Dey’s Medical Pvt. Ltd., Kolkata). 2007 (May- June): Hands on experience of working in NACO recommended HIV-AIDS laboratory in National Institute of Cholera and Enteric Diseases (NICED), Kolkata, as a summer training fellow on the topic, Immunoassays for Detection of HIV Antigen/Antibody’. TECHNICAL PROFICIENCIES Instrument handling: FPLC, HPLC, FACS, UV-Visible spectrophotometer, Fluorescence microscope, ELISA reader, FT-IR, etc. Experimental animal (viz. mouse, rabbit) handling (feeding, injection of drugs/cells, blood/fluid collection) for the purpose of antibody generation/assessment of effect of novel biomolecules and drugs/tumor development/tumor site detection and its analysis. A self driven, experienced biochemist with a strong desire for success in R&D of life Science industries. I am skilled in designing, execution and trouble-shooting of research processes. I’m a good team player with fine communication skills and a dependable leader when given free-hand.

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Souvik Dey, e-mail id: [email protected] Page 1

SOUVIK DEY

Address: Plot B, Gitanjali, Jheelbagan, 24 PGS (N), P.O.– Hatiara, Kolkata-700157, WB, India.

Contacts: (+001)3303892332 (USA) / (+91) 8013185609 Email ID: [email protected]

CAREER OBJECTIVES

Seeking a permanent position to utilize my abilities, technical skills and experience in the area

of research and development in life science/pharmaceutical industry while being resourceful,

innovative and flexible; I believe all these aspects will be helpful to deal with the challenges of

the industry, productively.

EXPERIENCE

2015 (November) – present: Working as a Post-doctoral Research Associate in the

Department of Biological Sciences, Kent State University, Ohio, USA. Here my goal is to

identify substrates of Protein kinase A and binding partners of Glycogen synthase kinase 3

using proteomics and molecular biological techniques in knock-out/transgenic mice models.

2010 (November) – 2015 (November): Worked as a Doctoral research scholar.

Successfully completed a DBT, GOI funded 4-year R&D project as a research scholar in the

Centre for Rural & Cryogenic Technologies, Jadavpur University on purification,

characterization, hormonal regulation and signal transduction mechanism of certain serum

glycoprotein related to treatment of male infertility.

2009 (January) - 2010 (November): Experience of research in cancer immunology as

Junior Research Fellow in Chittaranjan National Cancer Institute (CNCI), Kolkata.

2008 (July) & 2014 (August): Training in the GLP/GMP grade Quality Control

(Microbiology/Chemistry) laboratory in Pharmaceutical industry (viz. Dey’s Medical Pvt.

Ltd., Kolkata).

2007 (May- June): Hands on experience of working in NACO recommended HIV-AIDS

laboratory in National Institute of Cholera and Enteric Diseases (NICED), Kolkata, as a

summer training fellow on the topic, ‘Immunoassays for Detection of HIV

Antigen/Antibody’.

TECHNICAL PROFICIENCIES

Instrument handling: FPLC, HPLC, FACS, UV-Visible spectrophotometer, Fluorescence

microscope, ELISA reader, FT-IR, etc.

Experimental animal (viz. mouse, rabbit) handling (feeding, injection of drugs/cells,

blood/fluid collection) for the purpose of antibody generation/assessment of effect of novel

biomolecules and drugs/tumor development/tumor site detection and its analysis.

A self driven, experienced biochemist with a strong desire for success in R&D of life Science industries. I am skilled in designing, execution and trouble-shooting of research processes. I’m a good team player with fine communication skills and a dependable leader when given free-hand.

Souvik Dey, e-mail id: [email protected] Page 2

Generation of knock-out mice line using Cre-log system and their long-term maintenance

Column chromatography-techniques for purification of biomolecules (including Abs)

Proteolytic digestion and purification of peptides

Chemical coupling of purified protein/Ab with enzyme/fluorophore and polymer matrices.

Electrophoretic (native & SDS-PAGE, tube gel for pI estimation) and blotting techniques

(including immunoblot, Western blot and those used in clinical HIV detection labs.)

Protein pull-down, immunoprecipitation and co-immunoprecipitation techniques

Intracellular cAMP, Ca2+ measurements

Enzymatic assay development

Handling of human and animal blood/semen (for motility analysis) samples

Animal and microbial cell culture and assay techniques/ Cell line maintenance

Microscopic analysis of cell/ tissue samples by fluorescent/chemical staining

Scientific project writing and reporting

Maintenance of resources of scientific laboratory and Computer fundamentals (MS Office)

ACADEMIC RECORDS

Name of the

Examination

Percentage

/ Division

Name of The Institution Passed

From, Board/University & The Year

of Passing

Ph.D in Life Sc. &

Biotechnology

---

Jadavpur University, 2015

M.Sc. in Microbiology

&

Microbial Technology

66.93 / 1st

University of Kalyani, 2008

B.Sc. (Hons.) in

Physiology(10+2+3)

61.30 / 1st

University of Calcutta, 2006

FIELDS OF INTEREST

Chemistry of biomolecules: purification and structural/functional characterization

Drug development and therapeutic studies including immunotherapy

Signal transduction mechanisms in biological systems

Regulation of cell cycle/ malignant growths (cancer) and its control

Physiology of mammalian reproduction with special interest in human system

PUBLICATION AND PARTICIPATION

1. Dey Souvik, Roy Debarun, Majumder Gopal C., Mukherjee Biswajit, Bhattacharyya

Debdas. Role of forward-motility-stimulating factor as an extracellular activator of soluble

adenylyl cyclase. Molecular Reproduction & Development. (Impact factor: 2.52), 2015.

82(12): 1001-1014. (doi: 10.1002/mrd.22586).

2. Dey Souvik, Roy Debarun, Majumder Gopal C., Bhattacharyya Debdas. Extracellular

regulation of sperm transmembrane adenylyl cyclase by a forward motility stimulating

protein. PLoS One 9,e110669. doi 10.1371/journal.pone.0110669.(Impact factor: 3.53).

Souvik Dey, e-mail id: [email protected] Page 3

3. Dey Souvik, Roy Debarun, Majumder Gopal C., Bhattacharyya Debdas. Receptor

expression is essential for forward motility in the course of sperm cell maturation.

Biochemistry and Cell Biology (Impact factor: 2.915), 2014. 92(1): 43-52. (doi: 10.1139/bcb-

2013-0080).

4. Roy Debarun, Dey Souvik, Majumder Gopal C., Bhattacharyya Debdas. Role of epididymal

anti sticking factor in sperm capacitation. Biochem Biophys Res Commun. 2015. 463(4):948-

53. (Impact factor: 2.28) doi: 10.1016/j.bbrc.2015.06.040.

5. Roy Debarun, Dey Souvik, Majumder Gopal C, Bhattacharyya D. Occurrence of novel

Cu2+-dependent sialic acid-specific lectin, on the outer surface of mature caprine

spermatozoa. Glycoconjugate Journal. (Impact factor: 2.5).

6. Roy Debarun, Das Koushik, Mondol Subhasis, Bhowmick Debajit, Dey Souvik, Mukherjee

Biswajit, Majumder Gopal C., Bhattacharyya Debdas. Epididymal protein ASF is a D-

galactose-specific lectin with apoptotic effect on human breast cancer cell line MCF7.

International Journal of Biological Macromolecules. (Impact factor: 2.8), 2016. 84 208–220.

7. Roy Debarun, Dey Souvik, Majumder Gopal C., Bhattacharyya Debdas. Copper: a biphasic

regulator of caprine sperm forward progression. Syst Biol Reprod Med. (Impact factor:

1.847) 2014 Feb; 60(1):52-57. (doi:10.3109/ 19396368.2013.848243).

8. Majumder Gopal C, Saha Sudipta, Das Koushik, Nath Debjani, Maiti Arunima, Dey

Souvik, Roy Debarun, Chakrabarty Jitamanyu, Bhoumik Arpita, Ghosh Prasanta,

Banerjee Saswati, Mandal Mahitosh, Jaiswal Bijay S, Bhattacharyya Debdas and

DungDung Sandhya R. Role of Sperm Surface Molecules in Motility Regulation.

DOI: 10.1201/b18900-9 In book: Mammalian Endocrinology and Male Reproductive Biology,

Edition: 1, Chapter: 8, Publisher: CRC Press, Taylor & Francis Asia Pacific, New Delhi,

India., Editor: Shiokumar Singh, pp.197-244.

AWARDS AND HONOURS

1. Awarded Post-doctoral Research Associateship by Kent State University and

Cleveland Clinic, Ohio, USA, in 2015.

2. Awarded Senior Research Fellowship by Indian Council of Medical Research, in

2014.

3. Awarded Junior Research Fellowship (Project), by Dept. of Biotechnology, GOI in

2010.

4. Awarded CSIR-UGC NET (LS) in 2010 (all India rank-48) and 2008 by Council for

Scientific & Industrial Research-University Grant Commission, India.

5. Awarded Institutional fellowship for research by Chittaranjan National Cancer

Institute, Kolkata in 2009.

6. Qualified GATE-Life Sciences in 2009 (percentile-92.95/all India rank-905) and 2008

(percentile-91.49/all India rank-1125) by Human Resource Development Group, GOI.

7. Awarded National scholarship for performance in Madhyamik (10th standards) in 2001

by Govt. of West Bengal.

PERSONAL PROFILE

Date of Birth: 20th May, 1984

Languages known: Bengali, English, Hindi

Hobbies & Interests: Gardening, listening to music, watching meaningful movies.

Souvik Dey, e-mail id: [email protected] Page 4

REFEREES

1. Dr. Gopal Chandra Majumder, Senior Scientist, Centre for Rural & Cryoginic

Technologies, Jadavpur University. Kolkata. PIN: 700032, Ex. Scientist ‘F’ (Director

Grade), Indian Institute of Chemical Biology-CSIR, Kolkata. Ph.: 03324146965, Fax:

03324137121, Email: [email protected]

2. Dr. Debdas Bhattacharyya, Senior Scientific Officer and HOD, Division of Cryobiology,

Centre for Rural & Cryoginic Technologies, Jadavpur University. PIN: 700032, Ph.:

03324146965, Fax: 03324137121, Email: [email protected]

3. Dr. Biswajit Mukherjee, Professor, Department of Pharmaceutical Technology, Jadavpur

University, Kolkata. PIN: 700 032, Ph.: +91-33-2414-6666- Extn.- 2588 (Office) /2414-6677,

+91-33-2427-6026 (Home), Fax: +91-33-2414-6584, E-mail: [email protected]

4. Mr. Sandip Middya, Senior Biologist (R&D), Curadev Pharma Private Limited, B 87,

Sector 83, Noida, UP, PIN: 201305, Email: [email protected], Ph: +91-120-408

1818/19.

I hereby declare that the information stated above is true to the best of my

knowledge.

Souvik Dey

April, 2016