special procedures: tbi, tset and iort

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Rota%on # 11 Special Procedures: TBI, TSeT and IORT Mentor: Tim Waldron By Vibha Chaswal

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Page 1: Special Procedures: TBI, TSET and IORT

Rota%on  #  11  Special  Procedures:  TBI,  TSeT  and  

IORT  Mentor:  Tim  Waldron  

By    Vibha  Chaswal  

Page 2: Special Procedures: TBI, TSET and IORT

TBI  

•  Hand  MU  calcula%ons    •  Measuring  profiles  with  and  without  filter  

•  Simula%ons  and  Treatments  

•  Lung  block  manufacture  

•  Compensator  determina%on  and  placement  

•  Commissioning  procedure  discussion  with  TJW  

•  AAPM  report  17  

Page 3: Special Procedures: TBI, TSET and IORT

TBI  Goals  of  TBI:  •  Immunosuppression  -­‐  lymphocyte  elimina%on  to  allow  engraOment  

of  donor  bonemarrow  •  Eradica%on  of  malignant  cells  -­‐  leukemia,  lymphoma,  rarely  solid  

tumors  •  Eradica%on  of  cells  with  gene%c  disorders  -­‐  Fanconi's  anemia,  

thalassemia  major,  WiskoT-­‐Aldritch  syndrome  

Dosimetric  goals  of  TBI  (AAPM  report  17):  •   Dose  Homogeneity  within  10  %  •   Prescribed  dose  to  mid-­‐plane  •   Dose  rate  of  10-­‐15  cGy/min  •   Verifica%on  by  Port  films  within  reasonable  margin  •   Lung  Shielding  

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TSET  Goals  of  TSET:  •  Cutaneous  T  cell  lymphoma:  Mycosis  fungoides  

Dosimetric  goals  of  TSET  (AAPM  report  23):  •  Average  energy  at  treatment  plane  =  3-­‐7  MeV  •  Uniform  dose  to  the  en%re  skin  (ver%cal  uniformity  +/-­‐  8  %  

horizontal  +/-­‐  4  %  in    the  central  treatment  plane  •  X-­‐ray  back  ground  <  1  %  •   Dose  prescribed  to  a  point  •   High  dose  rate  treatment  •   Verifica%on  by  TLDs  •   Eye  shields  •  Boost  fields  for  under-­‐dosed  areas  

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1 Treatment Cycle per week over two days: Day 1 – AP/RPO/LPO Day 2 – PA/LAO/RAO

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Thank  You