special review of virginiamycin

1
News News News News 522 Australian Veterinary Journal Volume 82, No 9, September 2004 I n response to one of the recommendations of the Joint Expert Technical Advisory Committee on Antibiotics Resistance (JETACAR) report, the APVMA commenced a special review of virginiamycin, a member of the streptogramin class of antibiotics, in 2000. The special review, which involved an assessment of the likelihood of harm to humans arising from the use of virginiamycin in livestock, is nearing completion. Virginiamycin is now scheduled as a Prescription Animal Remedy and the AVA has taken an active interest in the risk management recommendations being proposed by APVMA. The AVA is a strong advocate of judicious use of antibiotics and in recent decades has developed and disseminated a number of guidelines and codes of practice to encourage and support prudent use. AVA is also committed to the enhancement of public health and a supporter of evidence-based decision making. The AVA believes that members of the veterinary profession share these commitments to appropriate use of antibiotics, to public health and to science based decisions. In recognition of these high standards of veterinary practice, the AVA has made a strong submission to the APVMA in defence of the profession. Despite the fact that an independent risk assessment concluded that the upper bound likelihood of harm in humans arising from the use of virginiamycin in livestock was equivalent to one extra death amongst the entire Australian population in the next 1000 years (it is difficult to consider a risk that is lower), the APVMA have recommended that the use of virginiamycin in cattle and sheep must be significantly restricted to a single short period of treatment once each year. This restraint is proposed even though it clearly defies the principles of good veterinary practice. In addition this restraint overrides each veterinarian’s clinical judgement and assessment of each unique situation. The AVA has argued in its submission that veterinarians, by virtue of prolonged and intensive training, education and experience, have the appropriate skills and experience to use their clinical judgement wisely and not to abuse or misuse virginiamycin to the detriment of public health. The AVA submission is currently under consideration by the Department of Health and by APVMA. A decision by APVMA on the continued use of virginiamycin is expected early this month. The AVA will prepare and publish a full report at this time. SPECIAL REVIEW OF VIRGINIAMYCIN By Kevin Doyle (AVA National Veterinary Director) A revolutionary new veterinary website LIDA (Listing of Inherited Disorders in Animals) appears set to improve pet owners, breeders and veterinarians understanding of specific dog breeds. Providing a comprehensive relational database, the innovative pet website uses non-technical descriptions and tables to make the task of choosing a healthy pet easier. Launched by AVA PetPEP patron Dr Katrina Warren on 25 August at the University of Sydney Faculty of Veterinary Science, LIDA will effectively enable potential dog owners to understand the specific problems different breeds may face. Dr Paul McGreevy, Senior Lecturer at the Faculty of Veterinary Science and one of the site developers says the benefits to veterinarians will be twofold. “Firstly, the site will assist veterinarians in helping clients who are purchasing a new puppy to make an informed choice and secondly it will serve as a handy reference source when vets are faced with one of the more uncommon inherited disorders,” Dr McGreevy said. “With more than 500 inheritable disorders and more than 180 breeds no vet can be expected to remember which disorder may affect which breeds. Some breeds have more than 60 disorders, so given the enormity of that task you really have to harness information technology to deliver this sort of data as cleanly as possible.” Three years in the making, LIDA is currently utilising data and reports from the Association of Veterinarians for Animal Rights in the United States to provide the foundation for a dynamic information pool. According to LIDA founders veterinarians, veterinary students and dog breeders have already provided terrific feedback on this resource that is designed to classify inherited disorders by breed and organ system in a relational database. Professor Frank Nicholas, internationally-renowned geneticist and another Faculty contributor to the site said more than 230 Australian small animal veterinary practices have agreed to contribute to this audit on an ongoing basis. “This will allow the delivery of on-line real-time reports of trends in these disorders to key stakeholders: the veterinary profession, dog breeders and potential puppy purchasers,” he said. The LIDA on-line initiative was developed in consultation with the Royal New South Wales Canine Council (RNSWCC), the Pet Industry Association of Australia (PIAA), the Royal Society for the Prevention of Cruelty to Animals (RSPCA) (Australia) and the Animal Welfare League (NSW). It was funded by the Canine Research and Veterinary Foundation and is supported by the AVA. There are now plans for LIDA to incorporate databases for other species including cats, horses, sheep and cattle. Pet website to monitor dog breed disorders By Mark Thornley Photo: Mark Thornley

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Page 1: SPECIAL REVIEW OF VIRGINIAMYCIN

NewsNewsNewsNews

522 Australian Veterinary Journal Volume 82, No 9, September 2004

In response to one of the recommendations of the Joint ExpertTechnical Advisory Committee on Antibiotics Resistance(JETACAR) report, the APVMA commenced a special review

of virginiamycin, a member of the streptogramin class ofantibiotics, in 2000. The special review, which involved anassessment of the likelihood of harm to humans arising from theuse of virginiamycin in livestock, is nearing completion.Virginiamycin is now scheduled as a Prescription Animal Remedyand the AVA has taken an active interest in the risk managementrecommendations being proposed by APVMA. The AVA is astrong advocate of judicious use of antibiotics and in recentdecades has developed and disseminated a number of guidelinesand codes of practice to encourage and support prudent use.

AVA is also committed to the enhancement of public healthand a supporter of evidence-based decision making. The AVAbelieves that members of the veterinary profession share thesecommitments to appropriate use of antibiotics, to public healthand to science based decisions.

In recognition of these high standards of veterinary practice,the AVA has made a strong submission to the APVMA indefence of the profession. Despite the fact that an independent

risk assessment concluded that the upper bound likelihood ofharm in humans arising from the use of virginiamycin inlivestock was equivalent to one extra death amongst the entireAustralian population in the next 1000 years (it is difficult toconsider a risk that is lower), the APVMA have recommendedthat the use of virginiamycin in cattle and sheep must besignificantly restricted to a single short period of treatment onceeach year.

This restraint is proposed even though it clearly defies theprinciples of good veterinary practice. In addition this restraintoverrides each veterinarian’s clinical judgement and assessmentof each unique situation. The AVA has argued in its submissionthat veterinarians, by virtue of prolonged and intensive training,education and experience, have the appropriate skills andexperience to use their clinical judgement wisely and not toabuse or misuse virginiamycin to the detriment of public health.The AVA submission is currently under consideration by theDepartment of Health and by APVMA. A decision by APVMAon the continued use of virginiamycin is expected early thismonth. The AVA will prepare and publish a full report at thistime.

SPECIAL REVIEW OF VIRGINIAMYCINBy Kevin Doyle (AVA National Veterinary Director)

Arevolutionary new veterinarywebsite LIDA (Listing ofInherited Disorders in

Animals) appears set to improve petowners, breeders and veterinariansunderstanding of specific dog breeds.

Providing a comprehensiverelational database, the innovative petwebsite uses non-technicaldescriptions and tables to make thetask of choosing a healthy pet easier.

Launched by AVA PetPEP patronDr Katrina Warren on 25 August atthe University of Sydney Faculty ofVeterinary Science, LIDA willeffectively enable potential dog owners tounderstand the specific problems differentbreeds may face.

Dr Paul McGreevy, Senior Lecturer atthe Faculty of Veterinary Science and oneof the site developers says the benefits toveterinarians will be twofold.

“Firstly, the site will assist veterinariansin helping clients who are purchasing anew puppy to make an informed choiceand secondly it will serve as a handyreference source when vets are faced withone of the more uncommon inheriteddisorders,” Dr McGreevy said.

“With more than 500 inheritabledisorders and more than 180 breeds no

vet can be expected to remember whichdisorder may affect which breeds. Somebreeds have more than 60 disorders, sogiven the enormity of that task you reallyhave to harness information technology todeliver this sort of data as cleanly aspossible.”

Three years in the making, LIDA iscurrently utilising data and reports fromthe Association of Veterinarians forAnimal Rights in the United States toprovide the foundation for a dynamicinformation pool.

According to LIDA foundersveterinarians, veterinary students and dogbreeders have already provided terrific

feedback on this resource that isdesigned to classify inheriteddisorders by breed and organ systemin a relational database.

Professor Frank Nicholas,internationally-renowned geneticistand another Faculty contributor tothe site said more than 230Australian small animal veterinarypractices have agreed to contributeto this audit on an ongoing basis.

“This will allow the delivery ofon-line real-time reports of trends inthese disorders to key stakeholders:

the veterinary profession, dogbreeders and potential puppy purchasers,”he said.

The LIDA on-line initiative wasdeveloped in consultation with the RoyalNew South Wales Canine Council(RNSWCC), the Pet Industry Associationof Australia (PIAA), the Royal Society forthe Prevention of Cruelty to Animals(RSPCA) (Australia) and the AnimalWelfare League (NSW). It was funded bythe Canine Research and VeterinaryFoundation and is supported by the AVA.

There are now plans for LIDA toincorporate databases for other speciesincluding cats, horses, sheep and cattle.

Pet website to monitor dog breed disordersBy Mark Thornley

Photo: Mark Thornley