GlycoNZ Ltd – a subsidiary of Kode Biotech Ltd GlycoNZ Limited PO Box 5965, Wellesley St, Auckland 1141, New Zealand Scott Laboratory Building – AUT University t: (+649) 921 9710 19 Mount St, Auckland, New Zealand

www.GlycoNZ.com

SPECIFICATION Biotinylated polymeric probe (BP)

6,6`-su2Lac-C2-PAA-biot Lac-6,6`-di-O-sulphate polyacrylamide biotin conjugate

_______________________________________________________________________________________

Catalogue ID number: Numéro d'identification du catalogue: 0901-BP

Ligand & spacer: 6-O-Su-Galβ1-4(6-O-Su)Glcβ-OCH2CH2NH2

Product synonym: Produit synonyme:

6,6`-su2Lac-C2-BP 6,6`-su2Lac-C2-PAA-biot Lac-6,6`-di-O-sulphate-C2-BP Lac-6,6`-di-O-sulphate-C2-PAA-biot 6-O-Su-Galβ1-4(6-O-Su)Glcβ-C2-PAA-biot 6-O-Su-Galβ1-4(6-O-Su)Glcβ-sp2-PAA-biot 6-O-Su-Galβ1-4(6-O-Su)Glcβ-OCH2CH2NH2-PAA-biot

Common name of ligand: Nom commun de ligand: Lac-6,6`-di-O-sulphate

Descriptive name: Nom descriptif:

Poly[N-(2-hydroxyethyl)acrylamide-co-N-(biot-(CH2)5)-acrylamide-co-N-(6,6`-su2Lac-C2)-acrylamide]

MW of ligand & spacer: MW de ligand & spacer:

567.5 (Na) Da

MW of glycoconjugate: MW de glycoconjugué: ~20 kDa

TECHNICAL SPECIFICATION - Spécifications techniques

Appearance: Apparence

Off-white to cream lyophilized powder Poudre lyophilisée blanc cassé à crème

Purity (1H NMR): Pureté (1H NMR): Min 95%

Identity (1H NMR): Identité (1H NMR):

Conforms to structure Conforme à la structure

Backbone: Colonne vertébrale: Poly[N-(2-hydroxyethyl)acrylamide-co-N-acrylamide]

Ligand content: Contenu du ligand: 20% mol.

Label: Étiquette

Biotin Biotine

Label content: Contenu de l'étiquette: 5%

DOCUMENT CONTROL - Contrôle des documents

Date of issue: Date d'Emission: 11-NOV-2019

Document ID: ID de document: 0901-BP-SPEC-191111

GlycoNZ Ltd – a subsidiary of Kode Biotech Ltd GlycoNZ Limited PO Box 5965, Wellesley St, Auckland 1141, New Zealand Scott Laboratory Building – AUT University t: (+649) 921 9710 19 Mount St, Auckland, New Zealand

www.GlycoNZ.com

SPECIFICATION Biotinylated polymeric probe (BP)

Glcβ6Glcβ-Gly-PAA-biot Gentiobiose polyacrylamide biotin conjugate

_______________________________________________________________________________________

Catalogue ID number: Numéro d'identification du catalogue: 0902-BP

Ligand & spacer: Glcβ1-6Glcβ-NHCOCH2NH2

Product synonym: Produit synonyme:

Glcβ6Glcβ-Gly-BP Glcβ6Glcβ-Gly-PAA-biot Gentiobiose-Gly-BP Gentiobiose-Gly-PAA-biot Glcβ1-6Glcβ-Gly-PAA-biot Glcβ1-6Glcβ-sp4-PAA-biot Glcβ1-6Glcβ-NHCOCH2NH2-PAA-biot

Common name of ligand: Nom commun de ligand: Gentiobiose

Descriptive name: Nom descriptif:

Poly[N-(2-hydroxyethyl)acrylamide-co-N-(biot-(CH2)5)-acrylamide-co-N-(Glcβ6Glcβ-Gly)-acrylamide]

MW of ligand & spacer: MW de ligand & spacer:

398.4 Da

MW of glycoconjugate: MW de glycoconjugué: ~20 kDa

TECHNICAL SPECIFICATION - Spécifications techniques

Appearance: Apparence

Off-white to cream lyophilized powder Poudre lyophilisée blanc cassé à crème

Purity (1H NMR): Pureté (1H NMR): Min 95%

Identity (1H NMR): Identité (1H NMR):

Conforms to structure Conforme à la structure

Backbone: Colonne vertébrale: Poly[N-(2-hydroxyethyl)acrylamide-co-N-acrylamide]

Ligand content: Contenu du ligand: 20% mol.

Label: Étiquette

Biotin Biotine

Label content: Contenu de l'étiquette: 5%

DOCUMENT CONTROL - Contrôle des documents

Date of issue: Date d'Emission: 11-NOV-2019

Document ID: ID de document: 0902-BP-SPEC-191111

GlycoNZ Ltd – a subsidiary of Kode Biotech Ltd GlycoNZ Limited PO Box 5965, Wellesley St, Auckland 1141, New Zealand Scott Laboratory Building – AUT University t: (+649) 921 9710 19 Mount St, Auckland, New Zealand

www.GlycoNZ.com

SPECIFICATION Biotinylated polymeric probe (BP)

Neu5Acβ6`LN-C3-PAA-biot 6`SiaβLacNAc polyacrylamide biotin conjugate

_______________________________________________________________________________________

Catalogue ID number: Numéro d'identification du catalogue: 0907-BP

Ligand & spacer: Neu5Acβ2-6Galβ1-4GlcNAcβ-OCH2CH2CH2NH2

Product synonym: Produit synonyme:

Neu5Acβ6`LN-C3-BP Neu5Acβ6`LN-C3-PAA-biot 6`SiaβLacNAc-C3-BP 6`SiaβLacNAc-C3-PAA-biot Neu5Acβ2-6Galβ1-4GlcNAcβ-C3-PAA-biot Neu5Acβ2-6Galβ1-4GlcNAcβ-sp3-PAA-biot Neu5Acβ2-6Galβ1-4GlcNAcβ-OCH2CH2CH2NH2-PAA-biot

Common name of ligand: Nom commun de ligand: 6`SiaβLacNAc

Descriptive name: Nom descriptif:

Poly[N-(2-hydroxyethyl)acrylamide-co-N-(biot-(CH2)5)-acrylamide-co-N-(Neu5Acβ6`LN-C3)-acrylamide]

MW of ligand & spacer: MW de ligand & spacer:

731.7 Da

MW of glycoconjugate: MW de glycoconjugué: ~20 kDa

TECHNICAL SPECIFICATION - Spécifications techniques

Appearance: Apparence

Off-white to cream lyophilized powder Poudre lyophilisée blanc cassé à crème

Purity (1H NMR): Pureté (1H NMR): Min 95%

Identity (1H NMR): Identité (1H NMR):

Conforms to structure Conforme à la structure

Backbone: Colonne vertébrale: Poly[N-(2-hydroxyethyl)acrylamide-co-N-acrylamide]

Ligand content: Contenu du ligand: 20% mol.

Label: Étiquette

Biotin Biotine

Label content: Contenu de l'étiquette: 5%

DOCUMENT CONTROL - Contrôle des documents

Date of issue: Date d'Emission: 12-NOV-2019

Document ID: ID de document: 0907-BP-SPEC-191112

GlycoNZ Ltd – a subsidiary of Kode Biotech Ltd GlycoNZ Limited PO Box 5965, Wellesley St, Auckland 1141, New Zealand Scott Laboratory Building – AUT University t: (+649) 921 9710 19 Mount St, Auckland, New Zealand

www.GlycoNZ.com

SPECIFICATION Biotinylated polymeric probe (BP)

Neu5Acα6`(6-su)LN-C3-PAA-biot 6`SLN-6-O-sulphate polyacrylamide biotin conjugate

_______________________________________________________________________________________

Catalogue ID number: Numéro d'identification du catalogue: 0908-BP

Ligand & spacer: Neu5Acα2-6Galβ1-4(6-O-Su)GlcNAcβ-OCH2CH2CH2NH2

Product synonym: Produit synonyme:

Neu5Acα6`(6-su)LN-C3-BP Neu5Acα6`(6-su)LN-C3-PAA-biot 6`SLN-6-O-sulphate-C3-BP 6`SLN-6-O-sulphate-C3-PAA-biot Neu5Acα2-6Galβ1-4(6-O-Su)GlcNAcβ-C3-PAA-biot Neu5Acα2-6Galβ1-4(6-O-Su)GlcNAcβ-sp3-PAA-biot Neu5Acα2-6Galβ1-4(6-O-Su)GlcNAcβ-OCH2CH2CH2NH2-PAA-biot

Common name of ligand: Nom commun de ligand: 6`SLN-6-O-sulphate

Descriptive name: Nom descriptif:

Poly[N-(2-hydroxyethyl)acrylamide-co-N-(biot-(CH2)5)-acrylamide-co-N-(Neu5Acα6`(6-su)LN-C3)-acrylamide]

MW of ligand & spacer: MW de ligand & spacer:

833.8 (Na) Da

MW of glycoconjugate: MW de glycoconjugué: ~20 kDa

TECHNICAL SPECIFICATION - Spécifications techniques

Appearance: Apparence

Off-white to cream lyophilized powder Poudre lyophilisée blanc cassé à crème

Purity (1H NMR): Pureté (1H NMR): Min 95%

Identity (1H NMR): Identité (1H NMR):

Conforms to structure Conforme à la structure

Backbone: Colonne vertébrale: Poly[N-(2-hydroxyethyl)acrylamide-co-N-acrylamide]

Ligand content: Contenu du ligand: 20% mol.

Label: Étiquette

Biotin Biotine

Label content: Contenu de l'étiquette: 5%

DOCUMENT CONTROL - Contrôle des documents

Date of issue: Date d'Emission: 12-NOV-2019

Document ID: ID de document: 0908-BP-SPEC-191112

GlycoNZ Ltd – a subsidiary of Kode Biotech Ltd GlycoNZ Limited PO Box 5965, Wellesley St, Auckland 1141, New Zealand Scott Laboratory Building – AUT University t: (+649) 921 9710 19 Mount St, Auckland, New Zealand

www.GlycoNZ.com

SPECIFICATION Biotinylated polymeric probe (BP)

4`-suLN-C2-PAA-biot 4`-Su-LacNAc polyacrylamide biotin conjugate

_______________________________________________________________________________________

Catalogue ID number: Numéro d'identification du catalogue: 0909a-BP

Ligand & spacer: 4-O-Su-Galβ1-4GlcNAcβ-OCH2CH2NH2

Product synonym: Produit synonyme:

4`-suLN-C2-BP 4`-suLN-C2-PAA-biot 4`-Su-LacNAc-C2-BP 4`-Su-LacNAc-C2-PAA-biot 4-O-Su-Galβ1-4GlcNAcβ-C2-PAA-biot 4-O-Su-Galβ1-4GlcNAcβ-sp2-PAA-biot 4-O-Su-Galβ1-4GlcNAcβ-OCH2CH2NH2-PAA-biot

Common name of ligand: Nom commun de ligand: 4`-Su-LacNAc

Descriptive name: Nom descriptif:

Poly[N-(2-hydroxyethyl)acrylamide-co-N-(biot-(CH2)5)-acrylamide-co-N-(4`-suLN-C2)-acrylamide]

MW of ligand & spacer: MW de ligand & spacer:

506.5 Da

MW of glycoconjugate: MW de glycoconjugué: ~20 kDa

TECHNICAL SPECIFICATION - Spécifications techniques

Appearance: Apparence

Off-white to cream lyophilized powder Poudre lyophilisée blanc cassé à crème

Purity (1H NMR): Pureté (1H NMR): Min 95%

Identity (1H NMR): Identité (1H NMR):

Conforms to structure Conforme à la structure

Backbone: Colonne vertébrale: Poly[N-(2-hydroxyethyl)acrylamide-co-N-acrylamide]

Ligand content: Contenu du ligand: 20% mol.

Label: Étiquette

Biotin Biotine

Label content: Contenu de l'étiquette: 5%

DOCUMENT CONTROL - Contrôle des documents

Date of issue: Date d'Emission: 12-NOV-2019

Document ID: ID de document: 0909a-BP-SPEC-191112

GlycoNZ Ltd – a subsidiary of Kode Biotech Ltd GlycoNZ Limited PO Box 5965, Wellesley St, Auckland 1141, New Zealand Scott Laboratory Building – AUT University t: (+649) 921 9710 19 Mount St, Auckland, New Zealand

www.GlycoNZ.com

SPECIFICATION Biotinylated polymeric probe (BP)

4`,6`-su2LN-C2-PAA-biot LacNAc-4`,6`-di-O-sulphate polyacrylamide biotin conjugate

_______________________________________________________________________________________

Catalogue ID number: Numéro d'identification du catalogue: 0918a-BP

Ligand & spacer: 4,6-O-Su2-Galβ1-4GlcNAcβ-OCH2CH2NH2

Product synonym: Produit synonyme:

4`,6`-su2LN-C2-BP 4`,6`-su2LN-C2-PAA-biot LacNAc-4`,6`-di-O-sulphate-C2-BP LacNAc-4`,6`-di-O-sulphate-C2-PAA-biot 4,6-O-Su2-Galβ1-4GlcNAcβ-C2-PAA-biot 4,6-O-Su2-Galβ1-4GlcNAcβ-sp2-PAA-biot 4,6-O-Su2-Galβ1-4GlcNAcβ-OCH2CH2NH2-PAA-biot

Common name of ligand: Nom commun de ligand: LacNAc-4`,6`-di-O-sulphate

Descriptive name: Nom descriptif:

Poly[N-(2-hydroxyethyl)acrylamide-co-N-(biot-(CH2)5)-acrylamide-co-N-(4`,6`-su2LN-C2)-acrylamide]

MW of ligand & spacer: MW de ligand & spacer:

608.5 (Na) Da

MW of glycoconjugate: MW de glycoconjugué: ~20 kDa

TECHNICAL SPECIFICATION - Spécifications techniques

Appearance: Apparence

Off-white to cream lyophilized powder Poudre lyophilisée blanc cassé à crème

Purity (1H NMR): Pureté (1H NMR): Min 95%

Identity (1H NMR): Identité (1H NMR):

Conforms to structure Conforme à la structure

Backbone: Colonne vertébrale: Poly[N-(2-hydroxyethyl)acrylamide-co-N-acrylamide]

Ligand content: Contenu du ligand: 20% mol.

Label: Étiquette

Biotin Biotine

Label content: Contenu de l'étiquette: 5%

DOCUMENT CONTROL - Contrôle des documents

Date of issue: Date d'Emission: 12-NOV-2019

Document ID: ID de document: 0918a-BP-SPEC-191112

GlycoNZ Ltd – a subsidiary of Kode Biotech Ltd GlycoNZ Limited PO Box 5965, Wellesley St, Auckland 1141, New Zealand Scott Laboratory Building – AUT University t: (+649) 921 9710 19 Mount St, Auckland, New Zealand

www.GlycoNZ.com

SPECIFICATION Biotinylated polymeric probe (BP)

4-suGlcNAcβ-C2-PAA-biot β-D-GlcNAc-4-O-sulfate polyacrylamide biotin conjugate

_______________________________________________________________________________________

Catalogue ID number: Numéro d'identification du catalogue: 0921-BP

Ligand & spacer: 4-O-Su-GlcNAcβ-OCH2CH2NH2

Product synonym: Produit synonyme:

4-suGlcNAcβ-C2-BP 4-suGlcNAcβ-C2-PAA-biot β-D-GlcNAc-4-O-sulfate-C2-BP β-D-GlcNAc-4-O-sulfate-C2-PAA-biot 4-O-Su-GlcNAcβ-C2-PAA-biot 4-O-Su-GlcNAcβ-sp2-PAA-biot 4-O-Su-GlcNAcβ-OCH2CH2NH2-PAA-biot

Common name of ligand: Nom commun de ligand: β-D-GlcNAc-4-O-sulfate

Descriptive name: Nom descriptif:

Poly[N-(2-hydroxyethyl)acrylamide-co-N-(biot-(CH2)5)-acrylamide-co-N-(4-suGlcNAcβ-C2)-acrylamide]

MW of ligand & spacer: MW de ligand & spacer:

344.4 Da

MW of glycoconjugate: MW de glycoconjugué: ~20 kDa

TECHNICAL SPECIFICATION - Spécifications techniques

Appearance: Apparence

Off-white to cream lyophilized powder Poudre lyophilisée blanc cassé à crème

Purity (1H NMR): Pureté (1H NMR): Min 95%

Identity (1H NMR): Identité (1H NMR):

Conforms to structure Conforme à la structure

Backbone: Colonne vertébrale: Poly[N-(2-hydroxyethyl)acrylamide-co-N-acrylamide]

Ligand content: Contenu du ligand: 20% mol.

Label: Étiquette

Biotin Biotine

Label content: Contenu de l'étiquette: 5%

DOCUMENT CONTROL - Contrôle des documents

Date of issue: Date d'Emission: 12-NOV-2019

Document ID: ID de document: 0921-BP-SPEC-191112

GlycoNZ Ltd – a subsidiary of Kode Biotech Ltd GlycoNZ Limited PO Box 5965, Wellesley St, Auckland 1141, New Zealand Scott Laboratory Building – AUT University t: (+649) 921 9710 19 Mount St, Auckland, New Zealand

www.GlycoNZ.com

SPECIFICATION Biotinylated polymeric probe (BP)

GalNAcα4GalNAcα-C3-PAA-biot GalNAcα4GalNAcα polyacrylamide biotin conjugate

_______________________________________________________________________________________

Catalogue ID number: Numéro d'identification du catalogue: 0922-BP

Ligand & spacer: GalNAcα1-4GalNAcα-OCH2CH2CH2NH2

Product synonym: Produit synonyme:

GalNAcα4GalNAcα-C3-BP GalNAcα4GalNAcα-C3-PAA-biot GalNAcα1-4GalNAcα-C3-PAA-biot GalNAcα1-4GalNAcα-sp3-PAA-biot GalNAcα1-4GalNAcα-OCH2CH2CH2NH2-PAA-biot

Common name of ligand: Nom commun de ligand: -

Descriptive name: Nom descriptif:

Poly[N-(2-hydroxyethyl)acrylamide-co-N-(biot-(CH2)5)-acrylamide-co-N-(GalNAcα4GalNAcα-C3)-acrylamide]

MW of ligand & spacer: MW de ligand & spacer:

481.5 Da

MW of glycoconjugate: MW de glycoconjugué: ~20 kDa

TECHNICAL SPECIFICATION - Spécifications techniques

Appearance: Apparence

Off-white to cream lyophilized powder Poudre lyophilisée blanc cassé à crème

Purity (1H NMR): Pureté (1H NMR): Min 95%

Identity (1H NMR): Identité (1H NMR):

Conforms to structure Conforme à la structure

Backbone: Colonne vertébrale: Poly[N-(2-hydroxyethyl)acrylamide-co-N-acrylamide]

Ligand content: Contenu du ligand: 20% mol.

Label: Étiquette

Biotin Biotine

Label content: Contenu de l'étiquette: 5%

DOCUMENT CONTROL - Contrôle des documents

Date of issue: Date d'Emission: 12-NOV-2019

Document ID: ID de document: 0922-BP-SPEC-191112

GlycoNZ Ltd – a subsidiary of Kode Biotech Ltd GlycoNZ Limited PO Box 5965, Wellesley St, Auckland 1141, New Zealand Scott Laboratory Building – AUT University t: (+649) 921 9710 19 Mount St, Auckland, New Zealand

www.GlycoNZ.com

SPECIFICATION Biotinylated polymeric probe (BP)

6`SLN3`LN-C3-PAA-biot Sia6`LN-LN polyacrylamide biotin conjugate

_______________________________________________________________________________________

Catalogue ID number: Numéro d'identification du catalogue: 0925-BP

Ligand & spacer: Neu5Acα2-6Galβ1-4GlcNAcβ1-3Galβ1-4GlcNAcβ-OCH2CH2CH2NH2

Product synonym: Produit synonyme:

6`SLN3`LN-C3-BP 6`SLN3`LN-C3-PAA-biot Sia6`LN-LN-C3-BP Sia6`LN-LN-C3-PAA-biot Neu5Acα2-6Galβ1-4GlcNAcβ1-3Galβ1-4GlcNAcβ-C3-PAA-biot Neu5Acα2-6Galβ1-4GlcNAcβ1-3Galβ1-4GlcNAcβ-sp3-PAA-biot Neu5Acα2-6Galβ1-4GlcNAcβ1-3Galβ1-4GlcNAcβ-OCH2CH2CH2NH2-PAA-biot

Common name of ligand: Nom commun de ligand: Sia6`LN-LN

Descriptive name: Nom descriptif:

Poly[N-(2-hydroxyethyl)acrylamide-co-N-(biot-(CH2)5)-acrylamide-co-N-(6`SLN3`LN -C3)-acrylamide]

MW of ligand & spacer: MW de ligand & spacer:

1097.1 Da

MW of glycoconjugate: MW de glycoconjugué: ~20 kDa

TECHNICAL SPECIFICATION - Spécifications techniques

Appearance: Apparence

Off-white to cream lyophilized powder Poudre lyophilisée blanc cassé à crème

Purity (1H NMR): Pureté (1H NMR): Min 95%

Identity (1H NMR): Identité (1H NMR):

Conforms to structure Conforme à la structure

Backbone: Colonne vertébrale: Poly[N-(2-hydroxyethyl)acrylamide-co-N-acrylamide]

Ligand content: Contenu du ligand: 20% mol.

Label: Étiquette

Biotin Biotine

Label content: Contenu de l'étiquette: 5%

DOCUMENT CONTROL - Contrôle des documents

Date of issue: Date d'Emission: 12-NOV-2019

Document ID: ID de document: 0925-BP-SPEC-191112

GlycoNZ Ltd – a subsidiary of Kode Biotech Ltd GlycoNZ Limited PO Box 5965, Wellesley St, Auckland 1141, New Zealand Scott Laboratory Building – AUT University t: (+649) 921 9710 19 Mount St, Auckland, New Zealand

www.GlycoNZ.com

SPECIFICATION Biotinylated polymeric probe (BP)

(Glcα4)4β-Gly-PAA-biot Maltotetraose polyacrylamide biotin conjugate

_______________________________________________________________________________________

Catalogue ID number: Numéro d'identification du catalogue: 0931-BP

Ligand & spacer: Glcα1-4Glcα1-4Glcα1-4Glcβ-NHCOCH2NH2

Product synonym: Produit synonyme:

(Glcα4)4β-Gly-BP (Glcα4)4β-Gly-PAA-biot maltotetraose-Gly-BP maltotetraose-Gly-PAA-biot Glcα1-4Glcα1-4Glcα1-4Glcβ-Gly-PAA-biot Glcα1-4Glcα1-4Glcα1-4Glcβ-sp4-PAA-biot Glcα1-4Glcα1-4Glcα1-4Glcβ-NHCOCH2NH2-PAA-biot

Common name of ligand: Nom commun de ligand: Maltotetraose

Descriptive name: Nom descriptif:

Poly[N-(2-hydroxyethyl)acrylamide-co-N-(biot-(CH2)5)-acrylamide-co-N-((Glcα4)4β-Gly)-acrylamide]

MW of ligand & spacer: MW de ligand & spacer:

722.7 Da

MW of glycoconjugate: MW de glycoconjugué: ~20 kDa

TECHNICAL SPECIFICATION - Spécifications techniques

Appearance: Apparence

Off-white to cream lyophilized powder Poudre lyophilisée blanc cassé à crème

Purity (1H NMR): Pureté (1H NMR): Min 95%

Identity (1H NMR): Identité (1H NMR):

Conforms to structure Conforme à la structure

Backbone: Colonne vertébrale: Poly[N-(2-hydroxyethyl)acrylamide-co-N-acrylamide]

Ligand content: Contenu du ligand: 20% mol.

Label: Étiquette

Biotin Biotine

Label content: Contenu de l'étiquette: 5%

DOCUMENT CONTROL - Contrôle des documents

Date of issue: Date d'Emission: 12-NOV-2019

Document ID: ID de document: 0931-BP-SPEC-191112

GlycoNZ Ltd – a subsidiary of Kode Biotech Ltd GlycoNZ Limited PO Box 5965, Wellesley St, Auckland 1141, New Zealand Scott Laboratory Building – AUT University t: (+649) 921 9710 19 Mount St, Auckland, New Zealand

www.GlycoNZ.com

SPECIFICATION Biotinylated polymeric probe (BP)

(Glcα4)3β-Gly-PAA-biot Maltotriose polyacrylamide biotin conjugate

_______________________________________________________________________________________

Catalogue ID number: Numéro d'identification du catalogue: 0932-BP

Ligand & spacer: Glcα1-4Glcα1-4Glcβ-NHCOCH2NH2

Product synonym: Produit synonyme:

(Glcα4)3β-Gly-BP (Glcα4)3β-Gly-PAA-biot maltotriose-Gly-BP maltotriose-Gly-PAA-biot Glcα1-4Glcα1-4Glcβ-Gly-PAA-biot Glcα1-4Glcα1-4Glcβ-sp4-PAA-biot Glcα1-4Glcα1-4Glcβ-NHCOCH2NH2-PAA-biot

Common name of ligand: Nom commun de ligand: Maltotriose

Descriptive name: Nom descriptif:

Poly[N-(2-hydroxyethyl)acrylamide-co-N-(biot-(CH2)5)-acrylamide-co-N-((Glcα4)3β-Gly)-acrylamide]

MW of ligand & spacer: MW de ligand & spacer:

560.5 Da

MW of glycoconjugate: MW de glycoconjugué: ~20 kDa

TECHNICAL SPECIFICATION - Spécifications techniques

Appearance: Apparence

Off-white to cream lyophilized powder Poudre lyophilisée blanc cassé à crème

Purity (1H NMR): Pureté (1H NMR): Min 95%

Identity (1H NMR): Identité (1H NMR):

Conforms to structure Conforme à la structure

Backbone: Colonne vertébrale: Poly[N-(2-hydroxyethyl)acrylamide-co-N-acrylamide]

Ligand content: Contenu du ligand: 20% mol.

Label: Étiquette

Biotin Biotine

Label content: Contenu de l'étiquette: 5%

DOCUMENT CONTROL - Contrôle des documents

Date of issue: Date d'Emission: 12-NOV-2019

Document ID: ID de document: 0932-BP-SPEC-191112

GlycoNZ Ltd – a subsidiary of Kode Biotech Ltd GlycoNZ Limited PO Box 5965, Wellesley St, Auckland 1141, New Zealand Scott Laboratory Building – AUT University t: (+649) 921 9710 19 Mount St, Auckland, New Zealand

www.GlycoNZ.com

SPECIFICATION Biotinylated polymeric probe (BP)

6`-su(3-Ac)LacdiNAc-C3-PAA-biot 3-O-Ac-LacdiNAc-6`-O-sulphate polyacrylamide biotin conjugate

_______________________________________________________________________________________

Catalogue ID number: Numéro d'identification du catalogue: 0934-BP

Ligand & spacer: 6-O-Su-GalNAcβ1-4(3-OAc)GlcNAcβ-OCH2CH2CH2NH2

Product synonym: Produit synonyme:

6`-su(3-Ac)LacdiNAc-C3-BP 6`-su(3-Ac)LacdiNAc-C3-PAA-biot 3-O-Ac-LacdiNAc-6`-O-sulphate-C3-BP 3-O-Ac-LacdiNAc-6`-O-sulphate-C3-PAA-biot 6-O-Su-GalNAcβ1-4(3-OAc)GlcNAcβ-C3-PAA-biot 6-O-Su-GalNAcβ1-4(3-OAc)GlcNAcβ-sp3-PAA-biot 6-O-Su-GalNAcβ1-4(3-OAc)GlcNAcβ-OCH2CH2CH2NH2-PAA-biot

Common name of ligand: Nom commun de ligand: 3-O-Ac-LacdiNAc-6`-O-sulphate

Descriptive name: Nom descriptif:

Poly[N-(2-hydroxyethyl)acrylamide-co-N-(biot-(CH2)5)-acrylamide-co-N-(6`-su(3-Ac)LacdiNAc-C3)-acrylamide]

MW of ligand & spacer: MW de ligand & spacer:

603.5 Da

MW of glycoconjugate: MW de glycoconjugué: ~20 kDa

TECHNICAL SPECIFICATION - Spécifications techniques

Appearance: Apparence

Off-white to cream lyophilized powder Poudre lyophilisée blanc cassé à crème

Purity (1H NMR): Pureté (1H NMR): Min 95%

Identity (1H NMR): Identité (1H NMR):

Conforms to structure Conforme à la structure

Backbone: Colonne vertébrale: Poly[N-(2-hydroxyethyl)acrylamide-co-N-acrylamide]

Ligand content: Contenu du ligand: 20% mol.

Label: Étiquette

Biotin Biotine

Label content: Contenu de l'étiquette: 5%

DOCUMENT CONTROL - Contrôle des documents

Date of issue: Date d'Emission: 12-NOV-2019

Document ID: ID de document: 0934-BP-SPEC-191112

GlycoNZ Ltd – a subsidiary of Kode Biotech Ltd GlycoNZ Limited PO Box 5965, Wellesley St, Auckland 1141, New Zealand Scott Laboratory Building – AUT University t: (+649) 921 9710 19 Mount St, Auckland, New Zealand

www.GlycoNZ.com

SPECIFICATION Biotinylated polymeric probe (BP)

4`,6`-su2LacdiNAc-C3-PAA-biot LacdiNAc-4`,6`-di-O-sulphate polyacrylamide biotin conjugate

_______________________________________________________________________________________

Catalogue ID number: Numéro d'identification du catalogue: 0935-BP

Ligand & spacer: 4,6-O-Su2-GalNAcβ1-4GlcNAcβ-OCH2CH2CH2NH2

Product synonym: Produit synonyme:

4`,6`-su2LacdiNAc-C3-BP 4`,6`-su2LacdiNAc-C3-PAA-biot LacdiNAc-4`,6`-di-O-sulphate-C3-BP LacdiNAc-4`,6`-di-O-sulphate-C3-PAA-biot 4,6-O-Su2-GalNAcβ1-4GlcNAcβ-C3-PAA-biot 4,6-O-Su2-GalNAcβ1-4GlcNAcβ-sp3-PAA-biot 4,6-O-Su2-GalNAcβ1-4GlcNAcβ-OCH2CH2CH2NH2-PAA-biot

Common name of ligand: Nom commun de ligand: LacdiNAc-4`,6`-di-O-sulphate

Descriptive name: Nom descriptif:

Poly[N-(2-hydroxyethyl)acrylamide-co-N-(biot-(CH2)5)-acrylamide-co-N-(4`,6`-su2LacdiNAc-C3)-acrylamide]

MW of ligand & spacer: MW de ligand & spacer:

663.5 (Na) Da

MW of glycoconjugate: MW de glycoconjugué: ~20 kDa

TECHNICAL SPECIFICATION - Spécifications techniques

Appearance: Apparence

Off-white to cream lyophilized powder Poudre lyophilisée blanc cassé à crème

Purity (1H NMR): Pureté (1H NMR): Min 95%

Identity (1H NMR): Identité (1H NMR):

Conforms to structure Conforme à la structure

Backbone: Colonne vertébrale: Poly[N-(2-hydroxyethyl)acrylamide-co-N-acrylamide]

Ligand content: Contenu du ligand: 20% mol.

Label: Étiquette

Biotin Biotine

Label content: Contenu de l'étiquette: 5%

DOCUMENT CONTROL - Contrôle des documents

Date of issue: Date d'Emission: 12-NOV-2019

Document ID: ID de document: 0935-BP-SPEC-191112

GlycoNZ Ltd – a subsidiary of Kode Biotech Ltd GlycoNZ Limited PO Box 5965, Wellesley St, Auckland 1141, New Zealand Scott Laboratory Building – AUT University t: (+649) 921 9710 19 Mount St, Auckland, New Zealand

www.GlycoNZ.com

SPECIFICATION Biotinylated polymeric probe (BP)

4`-suLacdiNAc-C3-PAA-biot 4`-O-su-LacdiNAc polyacrylamide biotin conjugate

_______________________________________________________________________________________

Catalogue ID number: Numéro d'identification du catalogue: 0936-BP

Ligand & spacer: 4-O-Su-GalNAcβ1-4GlcNAcβ-OCH2CH2CH2NH2

Product synonym: Produit synonyme:

4`-suLacdiNAc-C3-BP 4`-suLacdiNAc-C3-PAA-biot 4`-O-su-LacdiNAc-C3-BP 4`-O-su-LacdiNAc-C3-PAA-biot 4-O-Su-GalNAcβ1-4GlcNAcβ-C3-PAA-biot 4-O-Su-GalNAcβ1-4GlcNAcβ-sp3-PAA-biot 4-O-Su-GalNAcβ1-4GlcNAcβ-OCH2CH2CH2NH2-PAA-biot

Common name of ligand: Nom commun de ligand: 4`-O-su-LacdiNAc

Descriptive name: Nom descriptif:

Poly[N-(2-hydroxyethyl)acrylamide-co-N-(biot-(CH2)5)-acrylamide-co-N-(4`-suLacdiNAc-C3)-acrylamide]

MW of ligand & spacer: MW de ligand & spacer:

561.5 Da

MW of glycoconjugate: MW de glycoconjugué: ~20 kDa

TECHNICAL SPECIFICATION - Spécifications techniques

Appearance: Apparence

Off-white to cream lyophilized powder Poudre lyophilisée blanc cassé à crème

Purity (1H NMR): Pureté (1H NMR): Min 95%

Identity (1H NMR): Identité (1H NMR):

Conforms to structure Conforme à la structure

Backbone: Colonne vertébrale: Poly[N-(2-hydroxyethyl)acrylamide-co-N-acrylamide]

Ligand content: Contenu du ligand: 20% mol.

Label: Étiquette

Biotin Biotine

Label content: Contenu de l'étiquette: 5%

DOCUMENT CONTROL - Contrôle des documents

Date of issue: Date d'Emission: 12-NOV-2019

Document ID: ID de document: 0936-BP-SPEC-191112

GlycoNZ Ltd – a subsidiary of Kode Biotech Ltd GlycoNZ Limited PO Box 5965, Wellesley St, Auckland 1141, New Zealand Scott Laboratory Building – AUT University t: (+649) 921 9710 19 Mount St, Auckland, New Zealand

www.GlycoNZ.com

SPECIFICATION Biotinylated polymeric probe (BP)

6`-suLacdiNAc-C3-PAA-biot LacdiNAc-6`-O-sulphate polyacrylamide biotin conjugate

_______________________________________________________________________________________

Catalogue ID number: Numéro d'identification du catalogue: 0937-BP

Ligand & spacer: 6-O-Su-GalNAcβ1-4GlcNAcβ-OCH2CH2CH2NH2

Product synonym: Produit synonyme:

6`-suLacdiNAc-C3-BP 6`-suLacdiNAc-C3-PAA-biot LacdiNAc-6`-O-sulphate-C3-BP LacdiNAc-6`-O-sulphate-C3-PAA-biot 6-O-Su-GalNAcβ1-4GlcNAcβ-C3-PAA-biot 6-O-Su-GalNAcβ1-4GlcNAcβ-sp3-PAA-biot 6-O-Su-GalNAcβ1-4GlcNAcβ-OCH2CH2CH2NH2-PAA-biot

Common name of ligand: Nom commun de ligand: LacdiNAc-6`-O-sulphate

Descriptive name: Nom descriptif:

Poly[N-(2-hydroxyethyl)acrylamide-co-N-(biot-(CH2)5)-acrylamide-co-N-(6`-suLacdiNAc-C3)-acrylamide]

MW of ligand & spacer: MW de ligand & spacer:

561.5 Da

MW of glycoconjugate: MW de glycoconjugué: ~20 kDa

TECHNICAL SPECIFICATION - Spécifications techniques

Appearance: Apparence

Off-white to cream lyophilized powder Poudre lyophilisée blanc cassé à crème

Purity (1H NMR): Pureté (1H NMR): Min 95%

Identity (1H NMR): Identité (1H NMR):

Conforms to structure Conforme à la structure

Backbone: Colonne vertébrale: Poly[N-(2-hydroxyethyl)acrylamide-co-N-acrylamide]

Ligand content: Contenu du ligand: 20% mol.

Label: Étiquette

Biotin Biotine

Label content: Contenu de l'étiquette: 5%

DOCUMENT CONTROL - Contrôle des documents

Date of issue: Date d'Emission: 12-NOV-2019

Document ID: ID de document: 0937-BP-SPEC-191112

GlycoNZ Ltd – a subsidiary of Kode Biotech Ltd GlycoNZ Limited PO Box 5965, Wellesley St, Auckland 1141, New Zealand Scott Laboratory Building – AUT University t: (+649) 921 9710 19 Mount St, Auckland, New Zealand

www.GlycoNZ.com

SPECIFICATION Biotinylated polymeric probe (BP)

Glcβ4Glcβ-Gly-PAA-biot Cellobiose polyacrylamide biotin conjugate

_______________________________________________________________________________________

Catalogue ID number: Numéro d'identification du catalogue: 0938-BP

Ligand & spacer: Glcβ1-4Glcβ-NHCOCH2NH2

Product synonym: Produit synonyme:

Glcβ4Glcβ-Gly-BP Glcβ4Glcβ-Gly-PAA-biot Cellobiose-Gly-BP Cellobiose-Gly-PAA-biot Glcβ1-4Glcβ-Gly-PAA-biot Glcβ1-4Glcβ-sp4-PAA-biot Glcβ1-4Glcβ-NHCOCH2NH2-PAA-biot

Common name of ligand: Nom commun de ligand: Cellobiose

Descriptive name: Nom descriptif:

Poly[N-(2-hydroxyethyl)acrylamide-co-N-(biot-(CH2)5)-acrylamide-co-N-(Glcβ4Glcβ-Gly)-acrylamide]

MW of ligand & spacer: MW de ligand & spacer:

398.4 Da

MW of glycoconjugate: MW de glycoconjugué: ~20 kDa

TECHNICAL SPECIFICATION - Spécifications techniques

Appearance: Apparence

Off-white to cream lyophilized powder Poudre lyophilisée blanc cassé à crème

Purity (1H NMR): Pureté (1H NMR): Min 95%

Identity (1H NMR): Identité (1H NMR):

Conforms to structure Conforme à la structure

Backbone: Colonne vertébrale: Poly[N-(2-hydroxyethyl)acrylamide-co-N-acrylamide]

Ligand content: Contenu du ligand: 20% mol.

Label: Étiquette

Biotin Biotine

Label content: Contenu de l'étiquette: 5%

DOCUMENT CONTROL - Contrôle des documents

Date of issue: Date d'Emission: 12-NOV-2019

Document ID: ID de document: 0938-BP-SPEC-191112

GlycoNZ Ltd – a subsidiary of Kode Biotech Ltd GlycoNZ Limited PO Box 5965, Wellesley St, Auckland 1141, New Zealand Scott Laboratory Building – AUT University t: (+649) 921 9710 19 Mount St, Auckland, New Zealand

www.GlycoNZ.com

SPECIFICATION Biotinylated polymeric probe (BP)

3-suGlcNAcβ-C3-PAA-biot β-D-GlcNAc-3-O-sulfate polyacrylamide biotin conjugate

_______________________________________________________________________________________

Catalogue ID number: Numéro d'identification du catalogue: 0941-BP

Ligand & spacer: 3-O-Su-GlcNAcβ-OCH2CH2CH2NH2

Product synonym: Produit synonyme:

3-suGlcNAcβ-C3-BP 3-suGlcNAcβ-C3-PAA-biot β-D-GlcNAc-3-O-sulfate-C3-BP β-D-GlcNAc-3-O-sulfate-C3-PAA-biot 3-O-Su-GlcNAcβ-C3-PAA-biot 3-O-Su-GlcNAcβ-sp3-PAA-biot 3-O-Su-GlcNAcβ-OCH2CH2CH2NH2-PAA-biot

Common name of ligand: Nom commun de ligand: β-D-GlcNAc-3-O-sulfate

Descriptive name: Nom descriptif:

Poly[N-(2-hydroxyethyl)acrylamide-co-N-(biot-(CH2)5)-acrylamide-co-N-(3-suGlcNAcβ-C3)-acrylamide]

MW of ligand & spacer: MW de ligand & spacer:

358.4 Da

MW of glycoconjugate: MW de glycoconjugué: ~20 kDa

TECHNICAL SPECIFICATION - Spécifications techniques

Appearance: Apparence

Off-white to cream lyophilized powder Poudre lyophilisée blanc cassé à crème

Purity (1H NMR): Pureté (1H NMR): Min 95%

Identity (1H NMR): Identité (1H NMR):

Conforms to structure Conforme à la structure

Backbone: Colonne vertébrale: Poly[N-(2-hydroxyethyl)acrylamide-co-N-acrylamide]

Ligand content: Contenu du ligand: 20% mol.

Label: Étiquette

Biotin Biotine

Label content: Contenu de l'étiquette: 5%

DOCUMENT CONTROL - Contrôle des documents

Date of issue: Date d'Emission: 12-NOV-2019

Document ID: ID de document: 0941-BP-SPEC-191112

GlycoNZ Ltd – a subsidiary of Kode Biotech Ltd GlycoNZ Limited PO Box 5965, Wellesley St, Auckland 1141, New Zealand Scott Laboratory Building – AUT University t: (+649) 921 9710 19 Mount St, Auckland, New Zealand

www.GlycoNZ.com

SPECIFICATION Biotinylated polymeric probe (BP)

3`-suLacdiNAc-C3-PAA-biot LacdiNAc-3`-O-sulphate polyacrylamide biotin conjugate

_______________________________________________________________________________________

Catalogue ID number: Numéro d'identification du catalogue: 0942-BP

Ligand & spacer: 3-O-Su-GalNAcβ1-4GlcNAcβ-OCH2CH2CH2NH2

Product synonym: Produit synonyme:

3`-suLacdiNAc-C3-BP 3`-suLacdiNAc-C3-PAA-biot LacdiNAc-3`-O-sulphate-C3-BP LacdiNAc-3`-O-sulphate-C3-PAA-biot 3-O-Su-GalNAcβ1-4GlcNAcβ-C3-PAA-biot 3-O-Su-GalNAcβ1-4GlcNAcβ-sp3-PAA-biot 3-O-Su-GalNAcβ1-4GlcNAcβ-OCH2CH2CH2NH2-PAA-biot

Common name of ligand: Nom commun de ligand: LacdiNAc-3`-O-sulphate

Descriptive name: Nom descriptif:

Poly[N-(2-hydroxyethyl)acrylamide-co-N-(biot-(CH2)5)-acrylamide-co-N-(3`-suLacdiNAc-C3)-acrylamide]

MW of ligand & spacer: MW de ligand & spacer:

561.5 Da

MW of glycoconjugate: MW de glycoconjugué: ~20 kDa

TECHNICAL SPECIFICATION - Spécifications techniques

Appearance: Apparence

Off-white to cream lyophilized powder Poudre lyophilisée blanc cassé à crème

Purity (1H NMR): Pureté (1H NMR): Min 95%

Identity (1H NMR): Identité (1H NMR):

Conforms to structure Conforme à la structure

Backbone: Colonne vertébrale: Poly[N-(2-hydroxyethyl)acrylamide-co-N-acrylamide]

Ligand content: Contenu du ligand: 20% mol.

Label: Étiquette

Biotin Biotine

Label content: Contenu de l'étiquette: 5%

DOCUMENT CONTROL - Contrôle des documents

Date of issue: Date d'Emission: 12-NOV-2019

Document ID: ID de document: 0942-BP-SPEC-191112

GlycoNZ Ltd – a subsidiary of Kode Biotech Ltd GlycoNZ Limited PO Box 5965, Wellesley St, Auckland 1141, New Zealand Scott Laboratory Building – AUT University t: (+649) 921 9710 19 Mount St, Auckland, New Zealand

www.GlycoNZ.com

SPECIFICATION Biotinylated polymeric probe (BP)

Manα4Manβ-Gly-PAA-biot Man4Man polyacrylamide biotin conjugate

_______________________________________________________________________________________

Catalogue ID number: Numéro d'identification du catalogue: 0946-BP

Ligand & spacer: Manα1-4Manβ-NHCOCH2NH2

Product synonym: Produit synonyme:

Manα4Manβ-Gly-BP Manα4Manβ-Gly-PAA-biot Man4Man-Gly-BP Man4Man-Gly-PAA-biot Manα1-4Manβ-Gly-PAA-biot Manα1-4Manβ-sp4-PAA-biot Manα1-4Manβ-NHCOCH2NH2-PAA-biot

Common name of ligand: Nom commun de ligand: Man4Man

Descriptive name: Nom descriptif:

Poly[N-(2-hydroxyethyl)acrylamide-co-N-(biot-(CH2)5)-acrylamide-co-N-(Manα4Manβ-Gly)-acrylamide]

MW of ligand & spacer: MW de ligand & spacer:

398.4 Da

MW of glycoconjugate: MW de glycoconjugué: ~20 kDa

TECHNICAL SPECIFICATION - Spécifications techniques

Appearance: Apparence

Off-white to cream lyophilized powder Poudre lyophilisée blanc cassé à crème

Purity (1H NMR): Pureté (1H NMR): Min 95%

Identity (1H NMR): Identité (1H NMR):

Conforms to structure Conforme à la structure

Backbone: Colonne vertébrale: Poly[N-(2-hydroxyethyl)acrylamide-co-N-acrylamide]

Ligand content: Contenu du ligand: 20% mol.

Label: Étiquette

Biotin Biotine

Label content: Contenu de l'étiquette: 5%

DOCUMENT CONTROL - Contrôle des documents

Date of issue: Date d'Emission: 12-NOV-2019

Document ID: ID de document: 0946-BP-SPEC-191112

GlycoNZ Ltd – a subsidiary of Kode Biotech Ltd GlycoNZ Limited PO Box 5965, Wellesley St, Auckland 1141, New Zealand Scott Laboratory Building – AUT University t: (+649) 921 9710 19 Mount St, Auckland, New Zealand

www.GlycoNZ.com

SPECIFICATION Biotinylated polymeric probe (BP)

Neu5Acα3`(6-su)Lec-C3-PAA-biot 3`SiaLec-6-O-sulphate polyacrylamide biotin conjugate

_______________________________________________________________________________________

Catalogue ID number: Numéro d'identification du catalogue: 0949-BP

Ligand & spacer: Neu5Acα2-3Galβ1-3(6-O-Su)GlcNAcβ-OCH2CH2CH2NH2

Product synonym: Produit synonyme:

Neu5Acα3`(6-su)Lec-C3-BP Neu5Acα3`(6-su)Lec-C3-PAA-biot 3`SiaLec-6-O-sulphate-C3-BP 3`SiaLec-6-O-sulphate-C3-PAA-biot Neu5Acα2-3Galβ1-3(6-O-Su)GlcNAcβ-C3-PAA-biot Neu5Acα2-3Galβ1-3(6-O-Su)GlcNAcβ-sp3-PAA-biot Neu5Acα2-3Galβ1-3(6-O-Su)GlcNAcβ-OCH2CH2CH2NH2-PAA-biot

Common name of ligand: Nom commun de ligand: 3`SiaLec-6-O-sulphate

Descriptive name: Nom descriptif:

Poly[N-(2-hydroxyethyl)acrylamide-co-N-(biot-(CH2)5)-acrylamide-co-N-(Neu5Acα3`(6-su)Lec-C3)-acrylamide]

MW of ligand & spacer: MW de ligand & spacer:

833.8 (Na) Da

MW of glycoconjugate: MW de glycoconjugué: ~20 kDa

TECHNICAL SPECIFICATION - Spécifications techniques

Appearance: Apparence

Off-white to cream lyophilized powder Poudre lyophilisée blanc cassé à crème

Purity (1H NMR): Pureté (1H NMR): Min 95%

Identity (1H NMR): Identité (1H NMR):

Conforms to structure Conforme à la structure

Backbone: Colonne vertébrale: Poly[N-(2-hydroxyethyl)acrylamide-co-N-acrylamide]

Ligand content: Contenu du ligand: 20% mol.

Label: Étiquette

Biotin Biotine

Label content: Contenu de l'étiquette: 5%

DOCUMENT CONTROL - Contrôle des documents

Date of issue: Date d'Emission: 12-NOV-2019

Document ID: ID de document: 0949-BP-SPEC-191112

GlycoNZ Ltd – a subsidiary of Kode Biotech Ltd GlycoNZ Limited PO Box 5965, Wellesley St, Auckland 1141, New Zealand Scott Laboratory Building – AUT University t: (+649) 921 9710 19 Mount St, Auckland, New Zealand

www.GlycoNZ.com

SPECIFICATION Biotinylated polymeric probe (BP)

Neu5Acα3`(6-su)LN-C3-PAA-biot 3`SLN-6-O-sulphate polyacrylamide biotin conjugate

_______________________________________________________________________________________

Catalogue ID number: Numéro d'identification du catalogue: 0951-BP

Ligand & spacer: Neu5Acα2-3Galβ1-4(6-O-Su)GlcNAcβ-OCH2CH2CH2NH2

Product synonym: Produit synonyme:

Neu5Acα3`(6-su)LN-C3-BP Neu5Acα3`(6-su)LN-C3-PAA-biot 3`SLN-6-O-sulphate-C3-BP 3`SLN-6-O-sulphate-C3-PAA-biot Neu5Acα2-3Galβ1-4(6-O-Su)GlcNAcβ-C3-PAA-biot Neu5Acα2-3Galβ1-4(6-O-Su)GlcNAcβ-sp3-PAA-biot Neu5Acα2-3Galβ1-4(6-O-Su)GlcNAcβ-OCH2CH2CH2NH2-PAA-biot

Common name of ligand: Nom commun de ligand: 3`SLN-6-O-sulphate

Descriptive name: Nom descriptif:

Poly[N-(2-hydroxyethyl)acrylamide-co-N-(biot-(CH2)5)-acrylamide-co-N-(Neu5Acα3`(6-su)LN-C3)-acrylamide]

MW of ligand & spacer: MW de ligand & spacer:

833.8 (Na) Da

MW of glycoconjugate: MW de glycoconjugué: ~20 kDa

TECHNICAL SPECIFICATION - Spécifications techniques

Appearance: Apparence

Off-white to cream lyophilized powder Poudre lyophilisée blanc cassé à crème

Purity (1H NMR): Pureté (1H NMR): Min 95%

Identity (1H NMR): Identité (1H NMR):

Conforms to structure Conforme à la structure

Backbone: Colonne vertébrale: Poly[N-(2-hydroxyethyl)acrylamide-co-N-acrylamide]

Ligand content: Contenu du ligand: 20% mol.

Label: Étiquette

Biotin Biotine

Label content: Contenu de l'étiquette: 5%

DOCUMENT CONTROL - Contrôle des documents

Date of issue: Date d'Emission: 12-NOV-2019

Document ID: ID de document: 0951-BP-SPEC-191112

GlycoNZ Ltd – a subsidiary of Kode Biotech Ltd GlycoNZ Limited PO Box 5965, Wellesley St, Auckland 1141, New Zealand Scott Laboratory Building – AUT University t: (+649) 921 9710 19 Mount St, Auckland, New Zealand

www.GlycoNZ.com

SPECIFICATION Biotinylated polymeric probe (BP)

3-suGalNAcβ-C3-PAA-biot β-D-GalNAc-3-O-sulfate polyacrylamide biotin conjugate

_______________________________________________________________________________________

Catalogue ID number: Numéro d'identification du catalogue: 0952-BP

Ligand & spacer: 3-O-Su-GalNAcβ-OCH2CH2CH2NH2

Product synonym: Produit synonyme:

3-suGalNAcβ-C3-BP 3-suGalNAcβ-C3-PAA-biot β-D-GalNAc-3-O-sulfate-C3-BP β-D-GalNAc-3-O-sulfate -C3-PAA-biot 3-O-Su-GalNAcβ-C3-PAA-biot 3-O-Su-GalNAcβ-sp3-PAA-biot 3-O-Su-GalNAcβ-OCH2CH2CH2NH2-PAA-biot

Common name of ligand: Nom commun de ligand: β-D-GalNAc-3-O-sulfate

Descriptive name: Nom descriptif:

Poly[N-(2-hydroxyethyl)acrylamide-co-N-(biot-(CH2)5)-acrylamide-co-N-(3-suGalNAcβ-C3)-acrylamide]

MW of ligand & spacer: MW de ligand & spacer:

358.4 Da

MW of glycoconjugate: MW de glycoconjugué: ~20 kDa

TECHNICAL SPECIFICATION - Spécifications techniques

Appearance: Apparence

Off-white to cream lyophilized powder Poudre lyophilisée blanc cassé à crème

Purity (1H NMR): Pureté (1H NMR): Min 95%

Identity (1H NMR): Identité (1H NMR):

Conforms to structure Conforme à la structure

Backbone: Colonne vertébrale: Poly[N-(2-hydroxyethyl)acrylamide-co-N-acrylamide]

Ligand content: Contenu du ligand: 20% mol.

Label: Étiquette

Biotin Biotine

Label content: Contenu de l'étiquette: 5%

DOCUMENT CONTROL - Contrôle des documents

Date of issue: Date d'Emission: 12-NOV-2019

Document ID: ID de document: 0952-BP-SPEC-191112

GlycoNZ Ltd – a subsidiary of Kode Biotech Ltd GlycoNZ Limited PO Box 5965, Wellesley St, Auckland 1141, New Zealand Scott Laboratory Building – AUT University t: (+649) 921 9710 19 Mount St, Auckland, New Zealand

www.GlycoNZ.com

SPECIFICATION Biotinylated polymeric probe (BP)

4-suGalNAcβ-C3-PAA-biot β-D-GalNAc-4-O-sulfate polyacrylamide biotin conjugate

_______________________________________________________________________________________

Catalogue ID number: Numéro d'identification du catalogue: 0953-BP

Ligand & spacer: 4-O-Su-GalNAcβ-OCH2CH2CH2NH2

Product synonym: Produit synonyme:

4-suGalNAcβ-C3-BP 4-suGalNAcβ-C3-PAA-biot β-D-GalNAc-4-O-sulfate-C3-BP β-D-GalNAc-4-O-sulfate-C3-PAA-biot 4-O-Su-GalNAcβ-C3-PAA-biot 4-O-Su-GalNAcβ-sp3-PAA-biot 4-O-Su-GalNAcβ-OCH2CH2CH2NH2-PAA-biot

Common name of ligand: Nom commun de ligand: β-D-GalNAc-4-O-sulfate

Descriptive name: Nom descriptif:

Poly[N-(2-hydroxyethyl)acrylamide-co-N-(biot-(CH2)5)-acrylamide-co-N-(4-suGalNAcβ-C3)-acrylamide]

MW of ligand & spacer: MW de ligand & spacer:

358.4 Da

MW of glycoconjugate: MW de glycoconjugué: ~20 kDa

TECHNICAL SPECIFICATION - Spécifications techniques

Appearance: Apparence

Off-white to cream lyophilized powder Poudre lyophilisée blanc cassé à crème

Purity (1H NMR): Pureté (1H NMR): Min 95%

Identity (1H NMR): Identité (1H NMR):

Conforms to structure Conforme à la structure

Backbone: Colonne vertébrale: Poly[N-(2-hydroxyethyl)acrylamide-co-N-acrylamide]

Ligand content: Contenu du ligand: 20% mol.

Label: Étiquette

Biotin Biotine

Label content: Contenu de l'étiquette: 5%

DOCUMENT CONTROL - Contrôle des documents

Date of issue: Date d'Emission: 12-NOV-2019

Document ID: ID de document: 0953-BP-SPEC-191112

GlycoNZ Ltd – a subsidiary of Kode Biotech Ltd GlycoNZ Limited PO Box 5965, Wellesley St, Auckland 1141, New Zealand Scott Laboratory Building – AUT University t: (+649) 921 9710 19 Mount St, Auckland, New Zealand

www.GlycoNZ.com

SPECIFICATION Biotinylated polymeric probe (BP)

6,6`-Bn2-αLN-C3-PAA-biot αLacNAc-6,6`-di-O-Bn polyacrylamide biotin conjugate

_______________________________________________________________________________________

Catalogue ID number: Numéro d'identification du catalogue: 0954-BP

Ligand & spacer: 6-O-Bn-Galα1-4(6-O-Bn)GlcNAcβ-OCH2CH2CH2NH2

Product synonym: Produit synonyme:

6,6`-Bn2-αLN-C3-BP 6,6`-Bn2-αLN-C3-PAA-biot αLacNAc-6,6`-di-O-Bn-C3-BP αLacNAc-6,6`-di-O-Bn-C3-PAA-biot 6-O-Bn-Galα1-4(6-O-Bn)GlcNAcβ-C3-PAA-biot 6-O-Bn-Galα1-4(6-O-Bn)GlcNAcβ-sp3-PAA-biot 6-O-Bn-Galα1-4(6-O-Bn)GlcNAcβ-OCH2CH2CH2NH2-PAA-biot

Common name of ligand: Nom commun de ligand: αLacNAc-6,6`-di-O-Bn

Descriptive name: Nom descriptif:

Poly[N-(2-hydroxyethyl)acrylamide-co-N-(biot-(CH2)5)-acrylamide-co-N-(6,6`-Bn2-αLN-C3)-acrylamide]

MW of ligand & spacer: MW de ligand & spacer:

620.9 Da

MW of glycoconjugate: MW de glycoconjugué: ~20 kDa

TECHNICAL SPECIFICATION - Spécifications techniques

Appearance: Apparence

Off-white to cream lyophilized powder Poudre lyophilisée blanc cassé à crème

Purity (1H NMR): Pureté (1H NMR): Min 95%

Identity (1H NMR): Identité (1H NMR):

Conforms to structure Conforme à la structure

Backbone: Colonne vertébrale: Poly[N-(2-hydroxyethyl)acrylamide-co-N-acrylamide]

Ligand content: Contenu du ligand: 20% mol.

Label: Étiquette

Biotin Biotine

Label content: Contenu de l'étiquette: 5%

DOCUMENT CONTROL - Contrôle des documents

Date of issue: Date d'Emission: 12-NOV-2019

Document ID: ID de document: 0954-BP-SPEC-191112

GlycoNZ Ltd – a subsidiary of Kode Biotech Ltd GlycoNZ Limited PO Box 5965, Wellesley St, Auckland 1141, New Zealand Scott Laboratory Building – AUT University t: (+649) 921 9710 19 Mount St, Auckland, New Zealand

www.GlycoNZ.com

SPECIFICATION Biotinylated polymeric probe (BP)

(Galβ)2-3,4GN-C3-PAA-biot (Galβ)2-3,4GN polyacrylamide biotin conjugate

_______________________________________________________________________________________

Catalogue ID number: Numéro d'identification du catalogue: 0955-BP

Ligand & spacer: Galβ1-4(Galβ1-3)GlcNAcβ-OCH2CH2CH2NH2

Product synonym: Produit synonyme:

(Galβ)2-3,4GN-C3-BP (Galβ)2-3,4GN-C3-PAA-biot Galβ1-4(Galβ1-3)GlcNAcβ-C3-PAA-biot Galβ1-4(Galβ1-3)GlcNAcβ-sp3-PAA-biot Galβ1-4(Galβ1-3)GlcNAcβ-OCH2CH2CH2NH2-PAA-biot

Common name of ligand: Nom commun de ligand: -

Descriptive name: Nom descriptif:

Poly[N-(2-hydroxyethyl)acrylamide-co-N-(biot-(CH2)5)-acrylamide-co-N-((Galβ)2-3,4GN-C3)-acrylamide]

MW of ligand & spacer: MW de ligand & spacer:

602.6 Da

MW of glycoconjugate: MW de glycoconjugué: ~20 kDa

TECHNICAL SPECIFICATION - Spécifications techniques

Appearance: Apparence

Off-white to cream lyophilized powder Poudre lyophilisée blanc cassé à crème

Purity (1H NMR): Pureté (1H NMR): Min 95%

Identity (1H NMR): Identité (1H NMR):

Conforms to structure Conforme à la structure

Backbone: Colonne vertébrale: Poly[N-(2-hydroxyethyl)acrylamide-co-N-acrylamide]

Ligand content: Contenu du ligand: 20% mol.

Label: Étiquette

Biotin Biotine

Label content: Contenu de l'étiquette: 5%

DOCUMENT CONTROL - Contrôle des documents

Date of issue: Date d'Emission: 12-NOV-2019

Document ID: ID de document: 0955-BP-SPEC-191112

GlycoNZ Ltd – a subsidiary of Kode Biotech Ltd GlycoNZ Limited PO Box 5965, Wellesley St, Auckland 1141, New Zealand Scott Laboratory Building – AUT University t: (+649) 921 9710 19 Mount St, Auckland, New Zealand

www.GlycoNZ.com

SPECIFICATION Biotinylated polymeric probe (BP)

Neu5Gcα3`LN-C3-PAA-biot 3`Sia(Gc)LacNAc polyacrylamide biotin conjugate

_______________________________________________________________________________________

Catalogue ID number: Numéro d'identification du catalogue: 0956-BP

Ligand & spacer: Neu5Gcα2-3Galβ1-4GlcNAcβ-OCH2CH2CH2NH2

Product synonym: Produit synonyme:

Neu5Gcα3`LN-C3-BP Neu5Gcα3`LN-C3-PAA-biot 3`Sia(Gc)LacNAc-C3-BP 3`Sia(Gc)LacNAc-C3-PAA-biot Neu5Gcα2-3Galβ1-4GlcNAcβ-C3-PAA-biot Neu5Gcα2-3Galβ1-4GlcNAcβ-sp3-PAA-biot Neu5Gcα2-3Galβ1-4GlcNAcβ-OCH2CH2CH2NH2-PAA-biot

Common name of ligand: Nom commun de ligand: 3`Sia(Gc)LacNAc

Descriptive name: Nom descriptif:

Poly[N-(2-hydroxyethyl)acrylamide-co-N-(biot-(CH2)5)-acrylamide-co-N-(Neu5Gcα3`LN-C3)-acrylamide]

MW of ligand & spacer: MW de ligand & spacer:

747.7 Da

MW of glycoconjugate: MW de glycoconjugué: ~20 kDa

TECHNICAL SPECIFICATION - Spécifications techniques

Appearance: Apparence

Off-white to cream lyophilized powder Poudre lyophilisée blanc cassé à crème

Purity (1H NMR): Pureté (1H NMR): Min 95%

Identity (1H NMR): Identité (1H NMR):

Conforms to structure Conforme à la structure

Backbone: Colonne vertébrale: Poly[N-(2-hydroxyethyl)acrylamide-co-N-acrylamide]

Ligand content: Contenu du ligand: 20% mol.

Label: Étiquette

Biotin Biotine

Label content: Contenu de l'étiquette: 5%

DOCUMENT CONTROL - Contrôle des documents

Date of issue: Date d'Emission: 12-NOV-2019

Document ID: ID de document: 0956-BP-SPEC-191112

GlycoNZ Ltd – a subsidiary of Kode Biotech Ltd GlycoNZ Limited PO Box 5965, Wellesley St, Auckland 1141, New Zealand Scott Laboratory Building – AUT University t: (+649) 921 9710 19 Mount St, Auckland, New Zealand

www.GlycoNZ.com

SPECIFICATION Biotinylated polymeric probe (BP)

Neu5Gcα6`LN-C3-PAA-biot 6`Sia(Gc)LacNAc polyacrylamide biotin conjugate

_______________________________________________________________________________________

Catalogue ID number: Numéro d'identification du catalogue: 0957-BP

Ligand & spacer: Neu5Gcα2-6Galβ1-4GlcNAcβ-OCH2CH2CH2NH2

Product synonym: Produit synonyme:

Neu5Gcα6`LN-C3-BP Neu5Gcα6`LN-C3-PAA-biot 6`Sia(Gc)LacNAc-C3-BP 6`Sia(Gc)LacNAc-C3-PAA-biot Neu5Gcα2-6Galβ1-4GlcNAcβ-C3-PAA-biot Neu5Gcα2-6Galβ1-4GlcNAcβ-sp3-PAA-biot Neu5Gcα2-6Galβ1-4GlcNAcβ-OCH2CH2CH2NH2-PAA-biot

Common name of ligand: Nom commun de ligand: 6`Sia(Gc)LacNAc

Descriptive name: Nom descriptif:

Poly[N-(2-hydroxyethyl)acrylamide-co-N-(biot-(CH2)5)-acrylamide-co-N-(Neu5Gcα6`LN-C3)-acrylamide]

MW of ligand & spacer: MW de ligand & spacer:

747.7 Da

MW of glycoconjugate: MW de glycoconjugué: ~20 kDa

TECHNICAL SPECIFICATION - Spécifications techniques

Appearance: Apparence

Off-white to cream lyophilized powder Poudre lyophilisée blanc cassé à crème

Purity (1H NMR): Pureté (1H NMR): Min 95%

Identity (1H NMR): Identité (1H NMR):

Conforms to structure Conforme à la structure

Backbone: Colonne vertébrale: Poly[N-(2-hydroxyethyl)acrylamide-co-N-acrylamide]

Ligand content: Contenu du ligand: 20% mol.

Label: Étiquette

Biotin Biotine

Label content: Contenu de l'étiquette: 5%

DOCUMENT CONTROL - Contrôle des documents

Date of issue: Date d'Emission: 12-NOV-2019

Document ID: ID de document: 0957-BP-SPEC-191112

GlycoNZ Ltd – a subsidiary of Kode Biotech Ltd GlycoNZ Limited PO Box 5965, Wellesley St, Auckland 1141, New Zealand Scott Laboratory Building – AUT University t: (+649) 921 9710 19 Mount St, Auckland, New Zealand

www.GlycoNZ.com

SPECIFICATION Biotinylated polymeric probe (BP)

GlcNAcβ3`LN-C3-PAA-biot GlcNAcβ3`LacNAc polyacrylamide biotin conjugate

_______________________________________________________________________________________

Catalogue ID number: Numéro d'identification du catalogue: 0958a-BP

Ligand & spacer: GlcNAcβ1-3Galβ1-4GlcNAcβ-OCH2CH2CH2NH2

Product synonym: Produit synonyme:

GlcNAcβ3`LN-C3-BP GlcNAcβ3`LN-C3-PAA-biot GlcNAcβ3`LacNAc-C3-BP GlcNAcβ3`LacNAc-C3-PAA-biot GlcNAcβ1-3Galβ1-4GlcNAcβ-C3-PAA-biot GlcNAcβ1-3Galβ1-4GlcNAcβ-sp3-PAA-biot GlcNAcβ1-3Galβ1-4GlcNAcβ-OCH2CH2CH2NH2-PAA-biot

Common name of ligand: Nom commun de ligand: GlcNAcβ3`LacNAc

Descriptive name: Nom descriptif:

Poly[N-(2-hydroxyethyl)acrylamide-co-N-(biot-(CH2)5)-acrylamide-co-N-(GlcNAcβ3`LN-C3)-acrylamide]

MW of ligand & spacer: MW de ligand & spacer:

643.6 Da

MW of glycoconjugate: MW de glycoconjugué: ~20 kDa

TECHNICAL SPECIFICATION - Spécifications techniques

Appearance: Apparence

Off-white to cream lyophilized powder Poudre lyophilisée blanc cassé à crème

Purity (1H NMR): Pureté (1H NMR): Min 95%

Identity (1H NMR): Identité (1H NMR):

Conforms to structure Conforme à la structure

Backbone: Colonne vertébrale: Poly[N-(2-hydroxyethyl)acrylamide-co-N-acrylamide]

Ligand content: Contenu du ligand: 20% mol.

Label: Étiquette

Biotin Biotine

Label content: Contenu de l'étiquette: 5%

DOCUMENT CONTROL - Contrôle des documents

Date of issue: Date d'Emission: 12-NOV-2019

Document ID: ID de document: 0958a-BP-SPEC-191112

GlycoNZ Ltd – a subsidiary of Kode Biotech Ltd GlycoNZ Limited PO Box 5965, Wellesley St, Auckland 1141, New Zealand Scott Laboratory Building – AUT University t: (+649) 921 9710 19 Mount St, Auckland, New Zealand

www.GlycoNZ.com

SPECIFICATION Biotinylated polymeric probe (BP)

GlcNAcβ3`LN-C2-PAA-biot GlcNAcβ3`LacNAc polyacrylamide biotin conjugate

_______________________________________________________________________________________

Catalogue ID number: Numéro d'identification du catalogue: 0958-BP

Ligand & spacer: GlcNAcβ1-3Galβ1-4GlcNAcβ-OCH2CH2NH2

Product synonym: Produit synonyme:

GlcNAcβ3`LN-C2-BP GlcNAcβ3`LN-C2-PAA-biot GlcNAcβ3`LacNAc-C2-BP GlcNAcβ3`LacNAc-C2-PAA-biot GlcNAcβ1-3Galβ1-4GlcNAcβ-C2-PAA-biot GlcNAcβ1-3Galβ1-4GlcNAcβ-sp2-PAA-biot GlcNAcβ1-3Galβ1-4GlcNAcβ-OCH2CH2NH2-PAA-biot

Common name of ligand: Nom commun de ligand: GlcNAcβ3`LacNAc

Descriptive name: Nom descriptif:

Poly[N-(2-hydroxyethyl)acrylamide-co-N-(biot-(CH2)5)-acrylamide-co-N-(GlcNAcβ3`LN-C2)-acrylamide]

MW of ligand & spacer: MW de ligand & spacer:

629.6 Da

MW of glycoconjugate: MW de glycoconjugué: ~20 kDa

TECHNICAL SPECIFICATION - Spécifications techniques

Appearance: Apparence

Off-white to cream lyophilized powder Poudre lyophilisée blanc cassé à crème

Purity (1H NMR): Pureté (1H NMR): Min 95%

Identity (1H NMR): Identité (1H NMR):

Conforms to structure Conforme à la structure

Backbone: Colonne vertébrale: Poly[N-(2-hydroxyethyl)acrylamide-co-N-acrylamide]

Ligand content: Contenu du ligand: 20% mol.

Label: Étiquette

Biotin Biotine

Label content: Contenu de l'étiquette: 5%

DOCUMENT CONTROL - Contrôle des documents

Date of issue: Date d'Emission: 12-NOV-2019

Document ID: ID de document: 0958-BP-SPEC-191112

GlycoNZ Ltd – a subsidiary of Kode Biotech Ltd GlycoNZ Limited PO Box 5965, Wellesley St, Auckland 1141, New Zealand Scott Laboratory Building – AUT University t: (+649) 921 9710 19 Mount St, Auckland, New Zealand

www.GlycoNZ.com

SPECIFICATION Biotinylated polymeric probe (BP)

(Glcα6)3β-Gly-PAA-biot Isomaltotriose polyacrylamide biotin conjugate

_______________________________________________________________________________________

Catalogue ID number: Numéro d'identification du catalogue: 0959-BP

Ligand & spacer: Glcα1-6Glcα1-6Glcβ-NHCOCH2NH2

Product synonym: Produit synonyme:

(Glcα6)3β-Gly-BP (Glcα6)3β-Gly-PAA-biot isomaltotriose-Gly-BP isomaltotriose-Gly-PAA-biot Glcα1-6Glcα1-6Glcβ-Gly-PAA-biot Glcα1-6Glcα1-6Glcβ-sp4-PAA-biot Glcα1-6Glcα1-6Glcβ-NHCOCH2NH2-PAA-biot

Common name of ligand: Nom commun de ligand: Isomaltotriose

Descriptive name: Nom descriptif:

Poly[N-(2-hydroxyethyl)acrylamide-co-N-(biot-(CH2)5)-acrylamide-co-N-((Glcα6)3β-Gly)-acrylamide]

MW of ligand & spacer: MW de ligand & spacer:

560.5 Da

MW of glycoconjugate: MW de glycoconjugué: ~20 kDa

TECHNICAL SPECIFICATION - Spécifications techniques

Appearance: Apparence

Off-white to cream lyophilized powder Poudre lyophilisée blanc cassé à crème

Purity (1H NMR): Pureté (1H NMR): Min 95%

Identity (1H NMR): Identité (1H NMR):

Conforms to structure Conforme à la structure

Backbone: Colonne vertébrale: Poly[N-(2-hydroxyethyl)acrylamide-co-N-acrylamide]

Ligand content: Contenu du ligand: 20% mol.

Label: Étiquette

Biotin Biotine

Label content: Contenu de l'étiquette: 5%

DOCUMENT CONTROL - Contrôle des documents

Date of issue: Date d'Emission: 12-NOV-2019

Document ID: ID de document: 0959-BP-SPEC-191112

GlycoNZ Ltd – a subsidiary of Kode Biotech Ltd GlycoNZ Limited PO Box 5965, Wellesley St, Auckland 1141, New Zealand Scott Laboratory Building – AUT University t: (+649) 921 9710 19 Mount St, Auckland, New Zealand

www.GlycoNZ.com

SPECIFICATION Biotinylated polymeric probe (BP)

Galα3`Leb-C3-PAA-biot BLeb polyacrylamide biotin conjugate

_______________________________________________________________________________________

Catalogue ID number: Numéro d'identification du catalogue: 0966-BP

Ligand & spacer: Galα1-3(Fucα1-2)Galβ1-3(Fucα1-4)GlcNAcβ-OCH2CH2CH2NH2

Product synonym: Produit synonyme:

Galα3`Leb-C3-BP Galα3`Leb-C3-PAA-biot BLeb-C3-BP BLeb-C3-PAA-biot Galα1-3(Fucα1-2)Galβ1-3(Fucα1-4)GlcNAcβ-C3-PAA-biot Galα1-3(Fucα1-2)Galβ1-3(Fucα1-4)GlcNAcβ-sp3-PAA-biot Galα1-3(Fucα1-2)Galβ1-3(Fucα1-4)GlcNAcβ-OCH2CH2CH2NH2-PAA-biot

Common name of ligand: Nom commun de ligand: BLeb

Descriptive name: Nom descriptif:

Poly[N-(2-hydroxyethyl)acrylamide-co-N-(biot-(CH2)5)-acrylamide-co-N-(Galα3`Leb-C3)-acrylamide]

MW of ligand & spacer: MW de ligand & spacer:

894.9 Da

MW of glycoconjugate: MW de glycoconjugué: ~20 kDa

TECHNICAL SPECIFICATION - Spécifications techniques

Appearance: Apparence

Off-white to cream lyophilized powder Poudre lyophilisée blanc cassé à crème

Purity (1H NMR): Pureté (1H NMR): Min 95%

Identity (1H NMR): Identité (1H NMR):

Conforms to structure Conforme à la structure

Backbone: Colonne vertébrale: Poly[N-(2-hydroxyethyl)acrylamide-co-N-acrylamide]

Ligand content: Contenu du ligand: 20% mol.

Label: Étiquette

Biotin Biotine

Label content: Contenu de l'étiquette: 5%

DOCUMENT CONTROL - Contrôle des documents

Date of issue: Date d'Emission: 12-NOV-2019

Document ID: ID de document: 0966-BP-SPEC-191112

GlycoNZ Ltd – a subsidiary of Kode Biotech Ltd GlycoNZ Limited PO Box 5965, Wellesley St, Auckland 1141, New Zealand Scott Laboratory Building – AUT University t: (+649) 921 9710 19 Mount St, Auckland, New Zealand

www.GlycoNZ.com

SPECIFICATION Biotinylated polymeric probe (BP)

GalNAcα3`Ley-C3-PAA-biot ALey polyacrylamide biotin conjugate

_______________________________________________________________________________________

Catalogue ID number: Numéro d'identification du catalogue: 0967-BP

Ligand & spacer: GalNAcα1-3(Fucα1-2)Galβ1-4(Fucα1-4)GlcNAcβ-OCH2CH2CH2NH2

Product synonym: Produit synonyme:

GalNAcα3`Ley-C3-BP GalNAcα3`Ley-C3-PAA-biot ALey-C3-BP ALey-C3-PAA-biot GalNAcα1-3(Fucα1-2)Galβ1-4(Fucα1-4)GlcNAcβ-C3-PAA-biot GalNAcα1-3(Fucα1-2)Galβ1-4(Fucα1-4)GlcNAcβ-sp3-PAA-biot GalNAcα1-3(Fucα1-2)Galβ1-4(Fucα1-4)GlcNAcβ-OCH2CH2CH2NH2-PAA-biot

Common name of ligand: Nom commun de ligand: ALey

Descriptive name: Nom descriptif:

Poly[N-(2-hydroxyethyl)acrylamide-co-N-(biot-(CH2)5)-acrylamide-co-N-(GalNAcα3`Ley-C3)-acrylamide]

MW of ligand & spacer: MW de ligand & spacer:

935.9 Da

MW of glycoconjugate: MW de glycoconjugué: ~20 kDa

TECHNICAL SPECIFICATION - Spécifications techniques

Appearance: Apparence

Off-white to cream lyophilized powder Poudre lyophilisée blanc cassé à crème

Purity (1H NMR): Pureté (1H NMR): Min 95%

Identity (1H NMR): Identité (1H NMR):

Conforms to structure Conforme à la structure

Backbone: Colonne vertébrale: Poly[N-(2-hydroxyethyl)acrylamide-co-N-acrylamide]

Ligand content: Contenu du ligand: 20% mol.

Label: Étiquette

Biotin Biotine

Label content: Contenu de l'étiquette: 5%

DOCUMENT CONTROL - Contrôle des documents

Date of issue: Date d'Emission: 12-NOV-2019

Document ID: ID de document: 0967-BP-SPEC-191112

GlycoNZ Ltd – a subsidiary of Kode Biotech Ltd GlycoNZ Limited PO Box 5965, Wellesley St, Auckland 1141, New Zealand Scott Laboratory Building – AUT University t: (+649) 921 9710 19 Mount St, Auckland, New Zealand

www.GlycoNZ.com

SPECIFICATION Biotinylated polymeric probe (BP)

Galα3`Ley-C3-PAA-biot BLey polyacrylamide biotin conjugate

_______________________________________________________________________________________

Catalogue ID number: Numéro d'identification du catalogue: 0968-BP

Ligand & spacer: Galα1-3(Fucα1-2)Galβ1-4(Fucα1-4)GlcNAcβ-OCH2CH2CH2NH2

Product synonym: Produit synonyme:

Galα3`Ley-C3-BP Galα3`Ley-C3-PAA-biot BLey-C3-BP BLey-C3-PAA-biot Galα1-3(Fucα1-2)Galβ1-4(Fucα1-4)GlcNAcβ-C3-PAA-biot Galα1-3(Fucα1-2)Galβ1-4(Fucα1-4)GlcNAcβ-sp3-PAA-biot Galα1-3(Fucα1-2)Galβ1-4(Fucα1-4)GlcNAcβ-OCH2CH2CH2NH2-PAA-biot

Common name of ligand: Nom commun de ligand: BLey

Descriptive name: Nom descriptif:

Poly[N-(2-hydroxyethyl)acrylamide-co-N-(biot-(CH2)5)-acrylamide-co-N-(Galα3`Ley-C3)-acrylamide]

MW of ligand & spacer: MW de ligand & spacer:

894.9 Da

MW of glycoconjugate: MW de glycoconjugué: ~20 kDa

TECHNICAL SPECIFICATION - Spécifications techniques

Appearance: Apparence

Off-white to cream lyophilized powder Poudre lyophilisée blanc cassé à crème

Purity (1H NMR): Pureté (1H NMR): Min 95%

Identity (1H NMR): Identité (1H NMR):

Conforms to structure Conforme à la structure

Backbone: Colonne vertébrale: Poly[N-(2-hydroxyethyl)acrylamide-co-N-acrylamide]

Ligand content: Contenu du ligand: 20% mol.

Label: Étiquette

Biotin Biotine

Label content: Contenu de l'étiquette: 5%

DOCUMENT CONTROL - Contrôle des documents

Date of issue: Date d'Emission: 12-NOV-2019

Document ID: ID de document: 0968-BP-SPEC-191112

GlycoNZ Ltd – a subsidiary of Kode Biotech Ltd GlycoNZ Limited PO Box 5965, Wellesley St, Auckland 1141, New Zealand Scott Laboratory Building – AUT University t: (+649) 921 9710 19 Mount St, Auckland, New Zealand

www.GlycoNZ.com

SPECIFICATION Biotinylated polymeric probe (BP)

GlcNAcβ4Murβ-Gly-PAA-biot GlcNAcβ-Mur polyacrylamide biotin conjugate

_______________________________________________________________________________________

Catalogue ID number: Numéro d'identification du catalogue: 0972-BP

Ligand & spacer: GlcNAcβ1-4[3-O-CH(CH3)COOH]GlcNAcβ-NHCOCH2NH2

Product synonym: Produit synonyme:

GlcNAcβ4Murβ-Gly-BP GlcNAcβ4Murβ-Gly-PAA-biot GlcNAcβ-Mur-Gly-BP GlcNAcβ-Mur-Gly-PAA-biot GlcNAcβ1-4[3-O-CH(CH3)COOH]GlcNAcβ-Gly-PAA-biot GlcNAcβ1-4[3-O-CH(CH3)COOH]GlcNAcβ-sp4-PAA-biot GlcNAcβ1-4[3-O-CH(CH3)COOH]GlcNAcβ-NHCOCH2NH2-PAA-biot

Common name of ligand: Nom commun de ligand: GlcNAcβ-Mur

Descriptive name: Nom descriptif:

Poly[N-(2-hydroxyethyl)acrylamide-co-N-(biot-(CH2)5)-acrylamide-co-N-(GlcNAcβ4Murβ-Gly)-acrylamide]

MW of ligand & spacer: MW de ligand & spacer:

552.5 Da

MW of glycoconjugate: MW de glycoconjugué: ~20 kDa

TECHNICAL SPECIFICATION - Spécifications techniques

Appearance: Apparence

Off-white to cream lyophilized powder Poudre lyophilisée blanc cassé à crème

Purity (1H NMR): Pureté (1H NMR): Min 95%

Identity (1H NMR): Identité (1H NMR):

Conforms to structure Conforme à la structure

Backbone: Colonne vertébrale: Poly[N-(2-hydroxyethyl)acrylamide-co-N-acrylamide]

Ligand content: Contenu du ligand: 20% mol.

Label: Étiquette

Biotin Biotine

Label content: Contenu de l'étiquette: 5%

DOCUMENT CONTROL - Contrôle des documents

Date of issue: Date d'Emission: 12-NOV-2019

Document ID: ID de document: 0972-BP-SPEC-191112

GlycoNZ Ltd – a subsidiary of Kode Biotech Ltd GlycoNZ Limited PO Box 5965, Wellesley St, Auckland 1141, New Zealand Scott Laboratory Building – AUT University t: (+649) 921 9710 19 Mount St, Auckland, New Zealand

www.GlycoNZ.com

SPECIFICATION Biotinylated polymeric probe (BP)

GlcNAcβ4Murα-Gly-PAA-biot GlcNAcα-Mur polyacrylamide biotin conjugate

_______________________________________________________________________________________

Catalogue ID number: Numéro d'identification du catalogue: 0973-BP

Ligand & spacer: GlcNAcβ1-4[3-O-CH(CH3)COOH]GlcNAcα-NHCOCH2NH2

Product synonym: Produit synonyme:

GlcNAcβ4Murα-Gly-BP GlcNAcβ4Murα-Gly-PAA-biot GlcNAcα-Mur-Gly-BP GlcNAcα-Mur-Gly-PAA-biot GlcNAcβ1-4[3-O-CH(CH3)COOH]GlcNAcα-Gly-PAA-biot GlcNAcβ1-4[3-O-CH(CH3)COOH]GlcNAcα-sp4-PAA-biot GlcNAcβ1-4[3-O-CH(CH3)COOH]GlcNAcα-NHCOCH2NH2-PAA-biot

Common name of ligand: Nom commun de ligand: GlcNAcα-Mur

Descriptive name: Nom descriptif:

Poly[N-(2-hydroxyethyl)acrylamide-co-N-(biot-(CH2)5)-acrylamide-co-N-(GlcNAcβ4Murα-Gly)-acrylamide]

MW of ligand & spacer: MW de ligand & spacer:

552.5 Da

MW of glycoconjugate: MW de glycoconjugué: ~20 kDa

TECHNICAL SPECIFICATION - Spécifications techniques

Appearance: Apparence

Off-white to cream lyophilized powder Poudre lyophilisée blanc cassé à crème

Purity (1H NMR): Pureté (1H NMR): Min 95%

Identity (1H NMR): Identité (1H NMR):

Conforms to structure Conforme à la structure

Backbone: Colonne vertébrale: Poly[N-(2-hydroxyethyl)acrylamide-co-N-acrylamide]

Ligand content: Contenu du ligand: 20% mol.

Label: Étiquette

Biotin Biotine

Label content: Contenu de l'étiquette: 5%

DOCUMENT CONTROL - Contrôle des documents

Date of issue: Date d'Emission: 12-NOV-2019

Document ID: ID de document: 0973-BP-SPEC-191112

GlycoNZ Ltd – a subsidiary of Kode Biotech Ltd GlycoNZ Limited PO Box 5965, Wellesley St, Auckland 1141, New Zealand Scott Laboratory Building – AUT University t: (+649) 921 9710 19 Mount St, Auckland, New Zealand

www.GlycoNZ.com

SPECIFICATION Biotinylated polymeric probe (BP)

GlcAβ3Galβ-C3-PAA-biot GlcAβ3Galβ polyacrylamide biotin conjugate

_______________________________________________________________________________________

Catalogue ID number: Numéro d'identification du catalogue: 0976-BP

Ligand & spacer: GlcAβ1-3Galβ-OCH2CH2CH2NH2

Product synonym: Produit synonyme:

GlcAβ3Galβ-C3-BP GlcAβ3Galβ-C3-PAA-biot GlcAβ1-3Galβ-C3-PAA-biot GlcAβ1-3Galβ-sp3-PAA-biot GlcAβ1-3Galβ-OCH2CH2CH2NH2-PAA-biot

Common name of ligand: Nom commun de ligand: -

Descriptive name: Nom descriptif:

Poly[N-(2-hydroxyethyl)acrylamide-co-N-(biot-(CH2)5)-acrylamide-co-N-(GlcAβ3Galβ-C3)-acrylamide]

MW of ligand & spacer: MW de ligand & spacer:

413.4 Da

MW of glycoconjugate: MW de glycoconjugué: ~20 kDa

TECHNICAL SPECIFICATION - Spécifications techniques

Appearance: Apparence

Off-white to cream lyophilized powder Poudre lyophilisée blanc cassé à crème

Purity (1H NMR): Pureté (1H NMR): Min 95%

Identity (1H NMR): Identité (1H NMR):

Conforms to structure Conforme à la structure

Backbone: Colonne vertébrale: Poly[N-(2-hydroxyethyl)acrylamide-co-N-acrylamide]

Ligand content: Contenu du ligand: 20% mol.

Label: Étiquette

Biotin Biotine

Label content: Contenu de l'étiquette: 5%

DOCUMENT CONTROL - Contrôle des documents

Date of issue: Date d'Emission: 12-NOV-2019

Document ID: ID de document: 0976-BP-SPEC-191112

GlycoNZ Ltd – a subsidiary of Kode Biotech Ltd GlycoNZ Limited PO Box 5965, Wellesley St, Auckland 1141, New Zealand Scott Laboratory Building – AUT University t: (+649) 921 9710 19 Mount St, Auckland, New Zealand

www.GlycoNZ.com

SPECIFICATION Biotinylated polymeric probe (BP)

Neu5Acα6Tαα-C3-PAA-biot 6SiaTαα polyacrylamide biotin conjugate

_______________________________________________________________________________________

Catalogue ID number: Numéro d'identification du catalogue: 0977-BP

Ligand & spacer: Neu5Acα2-6(Galα1-3)GalNAcα-OCH2CH2CH2NH2

Product synonym: Produit synonyme:

Neu5Acα6Tαα-C3-BP Neu5Acα6Tαα -C3-PAA-biot 6SiaTαα-C3-BP

6SiaTαα-C3-PAA-biot Neu5Acα2-6(Galα1-3)GalNAcα-C3-PAA-biot Neu5Acα2-6(Galα1-3)GalNAcα-sp3-PAA-biot Neu5Acα2-6(Galα1-3)GalNAcα-OCH2CH2CH2NH2-PAA-biot

Common name of ligand: Nom commun de ligand: 6SiaTαα

Descriptive name: Nom descriptif:

Poly[N-(2-hydroxyethyl)acrylamide-co-N-(biot-(CH2)5)-acrylamide-co-N-(Neu5Acα6Tαα-C3)-acrylamide]

MW of ligand & spacer: MW de ligand & spacer:

731.7 Da

MW of glycoconjugate: MW de glycoconjugué: ~20 kDa

TECHNICAL SPECIFICATION - Spécifications techniques

Appearance: Apparence

Off-white to cream lyophilized powder Poudre lyophilisée blanc cassé à crème

Purity (1H NMR): Pureté (1H NMR): Min 95%

Identity (1H NMR): Identité (1H NMR):

Conforms to structure Conforme à la structure

Backbone: Colonne vertébrale: Poly[N-(2-hydroxyethyl)acrylamide-co-N-acrylamide]

Ligand content: Contenu du ligand: 20% mol.

Label: Étiquette

Biotin Biotine

Label content: Contenu de l'étiquette: 5%

DOCUMENT CONTROL - Contrôle des documents

Date of issue: Date d'Emission: 12-NOV-2019

Document ID: ID de document: 0977-BP-SPEC-191112

GlycoNZ Ltd – a subsidiary of Kode Biotech Ltd GlycoNZ Limited PO Box 5965, Wellesley St, Auckland 1141, New Zealand Scott Laboratory Building – AUT University t: (+649) 921 9710 19 Mount St, Auckland, New Zealand

www.GlycoNZ.com

SPECIFICATION Biotinylated polymeric probe (BP)

GlcAβ6Galβ-C3-PAA-biot GlcAβ6Galβ polyacrylamide biotin conjugate

_______________________________________________________________________________________

Catalogue ID number: Numéro d'identification du catalogue: 0978-BP

Ligand & spacer: GlcAβ1-6Galβ-OCH2CH2CH2NH2

Product synonym: Produit synonyme:

GlcAβ6Galβ-C3-BP GlcAβ6Galβ-C3-PAA-biot GlcAβ1-6Galβ-C3-PAA-biot GlcAβ1-6Galβ-sp3-PAA-biot GlcAβ1-6Galβ-OCH2CH2CH2NH2-PAA-biot

Common name of ligand: Nom commun de ligand: -

Descriptive name: Nom descriptif:

Poly[N-(2-hydroxyethyl)acrylamide-co-N-(biot-(CH2)5)-acrylamide-co-N-(GlcAβ6Galβ-C3)-acrylamide]

MW of ligand & spacer: MW de ligand & spacer:

413.4 Da

MW of glycoconjugate: MW de glycoconjugué: ~20 kDa

TECHNICAL SPECIFICATION - Spécifications techniques

Appearance: Apparence

Off-white to cream lyophilized powder Poudre lyophilisée blanc cassé à crème

Purity (1H NMR): Pureté (1H NMR): Min 95%

Identity (1H NMR): Identité (1H NMR):

Conforms to structure Conforme à la structure

Backbone: Colonne vertébrale: Poly[N-(2-hydroxyethyl)acrylamide-co-N-acrylamide]

Ligand content: Contenu du ligand: 20% mol.

Label: Étiquette

Biotin Biotine

Label content: Contenu de l'étiquette: 5%

DOCUMENT CONTROL - Contrôle des documents

Date of issue: Date d'Emission: 12-NOV-2019

Document ID: ID de document: 0978-BP-SPEC-191112

GlycoNZ Ltd – a subsidiary of Kode Biotech Ltd GlycoNZ Limited PO Box 5965, Wellesley St, Auckland 1141, New Zealand Scott Laboratory Building – AUT University t: (+649) 921 9710 19 Mount St, Auckland, New Zealand

www.GlycoNZ.com

SPECIFICATION Biotinylated polymeric probe (BP)

LN6TF-C3-PAA-biot LacNAc6TF polyacrylamide biotin conjugate

_______________________________________________________________________________________

Catalogue ID number: Numéro d'identification du catalogue: 0980-BP

Ligand & spacer: Galβ1-4GlcNAcβ1-6(Galβ1-3)GalNAcα-OCH2CH2CH2NH2

Product synonym: Produit synonyme:

LN6TF-C3-BP LN6TF-C3-PAA-biot LacNAc6TF-C3-BP LacNAc6TF-C3-PAA-biot Galβ1-4GlcNAcβ1-6(Galβ1-3)GalNAcα-C3-PAA-biot Galβ1-4GlcNAcβ1-6(Galβ1-3)GalNAcα-sp3-PAA-biot Galβ1-4GlcNAcβ1-6(Galβ1-3)GalNAcα-OCH2CH2CH2NH2-PAA-biot

Common name of ligand: Nom commun de ligand: LacNAc6TF

Descriptive name: Nom descriptif:

Poly[N-(2-hydroxyethyl)acrylamide-co-N-(biot-(CH2)5)-acrylamide-co-N-(LN6TF-C3)-acrylamide]

MW of ligand & spacer: MW de ligand & spacer:

805.8 Da

MW of glycoconjugate: MW de glycoconjugué: ~20 kDa

TECHNICAL SPECIFICATION - Spécifications techniques

Appearance: Apparence

Off-white to cream lyophilized powder Poudre lyophilisée blanc cassé à crème

Purity (1H NMR): Pureté (1H NMR): Min 95%

Identity (1H NMR): Identité (1H NMR):

Conforms to structure Conforme à la structure

Backbone: Colonne vertébrale: Poly[N-(2-hydroxyethyl)acrylamide-co-N-acrylamide]

Ligand content: Contenu du ligand: 20% mol.

Label: Étiquette

Biotin Biotine

Label content: Contenu de l'étiquette: 5%

DOCUMENT CONTROL - Contrôle des documents

Date of issue: Date d'Emission: 12-NOV-2019

Document ID: ID de document: 0980-BP-SPEC-191112

GlycoNZ Ltd – a subsidiary of Kode Biotech Ltd GlycoNZ Limited PO Box 5965, Wellesley St, Auckland 1141, New Zealand Scott Laboratory Building – AUT University t: (+649) 921 9710 19 Mount St, Auckland, New Zealand

www.GlycoNZ.com

SPECIFICATION Biotinylated polymeric probe (BP)

(GlcNAcβ4)3-Gly-PAA-biot Chitotriose polyacrylamide biotin conjugate

_______________________________________________________________________________________

Catalogue ID number: Numéro d'identification du catalogue: 0982-BP

Ligand & spacer: GlcNAcβ1-4GlcNAβ1-4GlcNAcβ-NHCOCH2NH2

Product synonym: Produit synonyme:

(GlcNAcβ4)3-Gly-BP (GlcNAcβ4)3-Gly-PAA-biot Chitotriose-Gly-BP Chitotriose-Gly-PAA-biot GlcNAcβ1-4GlcNAβ1-4GlcNAcβ-Gly-PAA-biot GlcNAcβ1-4GlcNAβ1-4GlcNAcβ-sp4-PAA-biot GlcNAcβ1-4GlcNAβ1-4GlcNAcβ-NHCOCH2NH2-PAA-biot

Common name of ligand: Nom commun de ligand: Chitotriose

Descriptive name: Nom descriptif:

Poly[N-(2-hydroxyethyl)acrylamide-co-N-(biot-(CH2)5)-acrylamide-co-N-((GlcNAcβ4)3-Gly)-acrylamide]

MW of ligand & spacer: MW de ligand & spacer:

683.6 Da

MW of glycoconjugate: MW de glycoconjugué: ~20 kDa

TECHNICAL SPECIFICATION - Spécifications techniques

Appearance: Apparence

Off-white to cream lyophilized powder Poudre lyophilisée blanc cassé à crème

Purity (1H NMR): Pureté (1H NMR): Min 95%

Identity (1H NMR): Identité (1H NMR):

Conforms to structure Conforme à la structure

Backbone: Colonne vertébrale: Poly[N-(2-hydroxyethyl)acrylamide-co-N-acrylamide]

Ligand content: Contenu du ligand: 20% mol.

Label: Étiquette

Biotin Biotine

Label content: Contenu de l'étiquette: 5%

DOCUMENT CONTROL - Contrôle des documents

Date of issue: Date d'Emission: 12-NOV-2019

Document ID: ID de document: 0982-BP-SPEC-191112

GlycoNZ Ltd – a subsidiary of Kode Biotech Ltd GlycoNZ Limited PO Box 5965, Wellesley St, Auckland 1141, New Zealand Scott Laboratory Building – AUT University t: (+649) 921 9710 19 Mount St, Auckland, New Zealand

www.GlycoNZ.com

SPECIFICATION Biotinylated polymeric probe (BP)

Neu5Acα6TF-C3-PAA-biot 6SiaTF polyacrylamide biotin conjugate

_______________________________________________________________________________________

Catalogue ID number: Numéro d'identification du catalogue: 0984-BP

Ligand & spacer: Neu5Acα2-6(Galβ1-3)GalNAcα-OCH2CH2CH2NH2

Product synonym: Produit synonyme:

Neu5Acα6TF-C3-BP Neu5Acα6TF-C3-PAA-biot 6SiaTF-C3-BP 6SiaTF-C3-PAA-biot Neu5Acα2-6(Galβ1-3)GalNAcα-C3-PAA-biot Neu5Acα2-6(Galβ1-3)GalNAcα-sp3-PAA-biot Neu5Acα2-6(Galβ1-3)GalNAcα-OCH2CH2CH2NH2-PAA-biot

Common name of ligand: Nom commun de ligand: 6SiaTF

Descriptive name: Nom descriptif:

Poly[N-(2-hydroxyethyl)acrylamide-co-N-(biot-(CH2)5)-acrylamide-co-N-(Neu5Acα6TF-C3)-acrylamide]

MW of ligand & spacer: MW de ligand & spacer:

731.7 Da

MW of glycoconjugate: MW de glycoconjugué: ~20 kDa

TECHNICAL SPECIFICATION - Spécifications techniques

Appearance: Apparence

Off-white to cream lyophilized powder Poudre lyophilisée blanc cassé à crème

Purity (1H NMR): Pureté (1H NMR): Min 95%

Identity (1H NMR): Identité (1H NMR):

Conforms to structure Conforme à la structure

Backbone: Colonne vertébrale: Poly[N-(2-hydroxyethyl)acrylamide-co-N-acrylamide]

Ligand content: Contenu du ligand: 20% mol.

Label: Étiquette

Biotin Biotine

Label content: Contenu de l'étiquette: 5%

DOCUMENT CONTROL - Contrôle des documents

Date of issue: Date d'Emission: 12-NOV-2019

Document ID: ID de document: 0984-BP-SPEC-191112

GlycoNZ Ltd – a subsidiary of Kode Biotech Ltd GlycoNZ Limited PO Box 5965, Wellesley St, Auckland 1141, New Zealand Scott Laboratory Building – AUT University t: (+649) 921 9710 19 Mount St, Auckland, New Zealand

www.GlycoNZ.com

SPECIFICATION Biotinylated polymeric probe (BP)

Neu5Acβ6TF-C3-PAA-biot 6SiaβTF polyacrylamide biotin conjugate

_______________________________________________________________________________________

Catalogue ID number: Numéro d'identification du catalogue: 0985-BP

Ligand & spacer: Neu5Acβ2-6(Galβ1-3)GalNAcα-OCH2CH2CH2NH2

Product synonym: Produit synonyme:

Neu5Acβ6TF-C3-BP Neu5Acβ6TF-C3-PAA-biot 6SiaβTF-C3-BP 6SiaβTF-C3-PAA-biot Neu5Acβ2-6(Galβ1-3)GalNAcα-C3-PAA-biot Neu5Acβ2-6(Galβ1-3)GalNAcα-sp3-PAA-biot Neu5Acβ2-6(Galβ1-3)GalNAcα-OCH2CH2CH2NH2-PAA-biot

Common name of ligand: Nom commun de ligand: 6SiaβTF

Descriptive name: Nom descriptif:

Poly[N-(2-hydroxyethyl)acrylamide-co-N-(biot-(CH2)5)-acrylamide-co-N-(Neu5Acβ6TF-C3)-acrylamide]

MW of ligand & spacer: MW de ligand & spacer:

731.7 Da

MW of glycoconjugate: MW de glycoconjugué: ~20 kDa

TECHNICAL SPECIFICATION - Spécifications techniques

Appearance: Apparence

Off-white to cream lyophilized powder Poudre lyophilisée blanc cassé à crème

Purity (1H NMR): Pureté (1H NMR): Min 95%

Identity (1H NMR): Identité (1H NMR):

Conforms to structure Conforme à la structure

Backbone: Colonne vertébrale: Poly[N-(2-hydroxyethyl)acrylamide-co-N-acrylamide]

Ligand content: Contenu du ligand: 20% mol.

Label: Étiquette

Biotin Biotine

Label content: Contenu de l'étiquette: 5%

DOCUMENT CONTROL - Contrôle des documents

Date of issue: Date d'Emission: 12-NOV-2019

Document ID: ID de document: 0985-BP-SPEC-191112

GlycoNZ Ltd – a subsidiary of Kode Biotech Ltd GlycoNZ Limited PO Box 5965, Wellesley St, Auckland 1141, New Zealand Scott Laboratory Building – AUT University t: (+649) 921 9710 19 Mount St, Auckland, New Zealand

www.GlycoNZ.com

SPECIFICATION Biotinylated polymeric probe (BP)

Neu5Acβ6GalNAcα-C3-PAA-biot SiaβTn polyacrylamide biotin conjugate

_______________________________________________________________________________________

Catalogue ID number: Numéro d'identification du catalogue: 0986-BP

Ligand & spacer: Neu5Acβ2-6GalNAcα-OCH2CH2CH2NH2

Product synonym: Produit synonyme:

Neu5Acβ6GalNAcα-C3-BP Neu5Acβ6GalNAcα-C3-PAA-biot SiaβTn-C3-BP SiaβTn-C3-PAA-biot Neu5Acβ2-6GalNAcα-C3-PAA-biot Neu5Acβ2-6GalNAcα-sp3-PAA-biot Neu5Acβ2-6GalNAcα-OCH2CH2CH2NH2-PAA-biot

Common name of ligand: Nom commun de ligand: SiaβTn

Descriptive name: Nom descriptif:

Poly[N-(2-hydroxyethyl)acrylamide-co-N-(biot-(CH2)5)-acrylamide-co-N-(Neu5Acβ6GalNAcα-C3)-acrylamide]

MW of ligand & spacer: MW de ligand & spacer:

569.6 Da

MW of glycoconjugate: MW de glycoconjugué: ~20 kDa

TECHNICAL SPECIFICATION - Spécifications techniques

Appearance: Apparence

Off-white to cream lyophilized powder Poudre lyophilisée blanc cassé à crème

Purity (1H NMR): Pureté (1H NMR): Min 95%

Identity (1H NMR): Identité (1H NMR):

Conforms to structure Conforme à la structure

Backbone: Colonne vertébrale: Poly[N-(2-hydroxyethyl)acrylamide-co-N-acrylamide]

Ligand content: Contenu du ligand: 20% mol.

Label: Étiquette

Biotin Biotine

Label content: Contenu de l'étiquette: 5%

DOCUMENT CONTROL - Contrôle des documents

Date of issue: Date d'Emission: 12-NOV-2019

Document ID: ID de document: 0986-BP-SPEC-191112

GlycoNZ Ltd – a subsidiary of Kode Biotech Ltd GlycoNZ Limited PO Box 5965, Wellesley St, Auckland 1141, New Zealand Scott Laboratory Building – AUT University t: (+649) 921 9710 19 Mount St, Auckland, New Zealand

www.GlycoNZ.com

SPECIFICATION Biotinylated polymeric probe (BP)

Galα4GalNAcα-C3-PAA-biot Galα4GalNAcα polyacrylamide biotin conjugate

_______________________________________________________________________________________

Catalogue ID number: Numéro d'identification du catalogue: 0991-BP

Ligand & spacer: Galα1-4GalNAcα-OCH2CH2CH2NH2

Product synonym: Produit synonyme:

Galα4GalNAcα-C3-BP Galα4GalNAcα-C3-PAA-biot Galα1-4GalNAcα-C3-PAA-biot Galα1-4GalNAcα-sp3-PAA-biot Galα1-4GalNAcα-OCH2CH2CH2NH2-PAA-biot

Common name of ligand: Nom commun de ligand: -

Descriptive name: Nom descriptif:

Poly[N-(2-hydroxyethyl)acrylamide-co-N-(biot-(CH2)5)-acrylamide-co-N-(Galα4GalNAcα-C3)-acrylamide]

MW of ligand & spacer: MW de ligand & spacer:

440.5 Da

MW of glycoconjugate: MW de glycoconjugué: ~20 kDa

TECHNICAL SPECIFICATION - Spécifications techniques

Appearance: Apparence

Off-white to cream lyophilized powder Poudre lyophilisée blanc cassé à crème

Purity (1H NMR): Pureté (1H NMR): Min 95%

Identity (1H NMR): Identité (1H NMR):

Conforms to structure Conforme à la structure

Backbone: Colonne vertébrale: Poly[N-(2-hydroxyethyl)acrylamide-co-N-acrylamide]

Ligand content: Contenu du ligand: 20% mol.

Label: Étiquette

Biotin Biotine

Label content: Contenu de l'étiquette: 5%

DOCUMENT CONTROL - Contrôle des documents

Date of issue: Date d'Emission: 12-NOV-2019

Document ID: ID de document: 0991-BP-SPEC-191112

GlycoNZ Ltd – a subsidiary of Kode Biotech Ltd GlycoNZ Limited PO Box 5965, Wellesley St, Auckland 1141, New Zealand Scott Laboratory Building – AUT University t: (+649) 921 9710 19 Mount St, Auckland, New Zealand

www.GlycoNZ.com

SPECIFICATION Biotinylated polymeric probe (BP)

Neu5Acα3GalNAcα-C3-PAA-biot 3-SiaTn polyacrylamide biotin conjugate

_______________________________________________________________________________________

Catalogue ID number: Numéro d'identification du catalogue: 0993-BP

Ligand & spacer: Neu5Acα2-3GalNAcα-OCH2CH2CH2NH2

Product synonym: Produit synonyme:

Neu5Acα3GalNAcα-C3-BP Neu5Acα3GalNAcα-C3-PAA-biot 3-SiaTn-C3-BP 3-SiaTn-C3-PAA-biot Neu5Acα2-3GalNAcα-C3-PAA-biot Neu5Acα2-3GalNAcα-sp3-PAA-biot Neu5Acα2-3GalNAcα-OCH2CH2CH2NH2-PAA-biot

Common name of ligand: Nom commun de ligand: 3-SiaTn

Descriptive name: Nom descriptif:

Poly[N-(2-hydroxyethyl)acrylamide-co-N-(biot-(CH2)5)-acrylamide-co-N-(Neu5Acα3GalNAcα-C3)-acrylamide]

MW of ligand & spacer: MW de ligand & spacer:

569.6 Da

MW of glycoconjugate: MW de glycoconjugué: ~20 kDa

TECHNICAL SPECIFICATION - Spécifications techniques

Appearance: Apparence

Off-white to cream lyophilized powder Poudre lyophilisée blanc cassé à crème

Purity (1H NMR): Pureté (1H NMR): Min 95%

Identity (1H NMR): Identité (1H NMR):

Conforms to structure Conforme à la structure

Backbone: Colonne vertébrale: Poly[N-(2-hydroxyethyl)acrylamide-co-N-acrylamide]

Ligand content: Contenu du ligand: 20% mol.

Label: Étiquette

Biotin Biotine

Label content: Contenu de l'étiquette: 5%

DOCUMENT CONTROL - Contrôle des documents

Date of issue: Date d'Emission: 12-NOV-2019

Document ID: ID de document: 0993-BP-SPEC-191112

GlycoNZ Ltd – a subsidiary of Kode Biotech Ltd GlycoNZ Limited PO Box 5965, Wellesley St, Auckland 1141, New Zealand Scott Laboratory Building – AUT University t: (+649) 921 9710 19 Mount St, Auckland, New Zealand

www.GlycoNZ.com

SPECIFICATION Biotinylated polymeric probe (BP)

LN3GalNAcα-C3-PAA-biot LacNAc3Tn polyacrylamide biotin conjugate

_______________________________________________________________________________________

Catalogue ID number: Numéro d'identification du catalogue: 0995-BP

Ligand & spacer: Galβ1-4GlcNAβ1-3GalNAcα-OCH2CH2CH2NH2

Product synonym: Produit synonyme:

LN3GalNAcα-C3-BP LN3GalNAcα-C3-PAA-biot LacNAc3Tn-C3-BP LacNAc3Tn-C3-PAA-biot Galβ1-4GlcNAβ1-3GalNAcα-C3-PAA-biot Galβ1-4GlcNAβ1-3GalNAcα-sp3-PAA-biot Galβ1-4GlcNAβ1-3GalNAcα-OCH2CH2CH2NH2-PAA-biot

Common name of ligand: Nom commun de ligand: LacNAc3Tn

Descriptive name: Nom descriptif:

Poly[N-(2-hydroxyethyl)acrylamide-co-N-(biot-(CH2)5)-acrylamide-co-N-(LN3GalNAcα-C3)-acrylamide]

MW of ligand & spacer: MW de ligand & spacer:

643.6 Da

MW of glycoconjugate: MW de glycoconjugué: ~20 kDa

TECHNICAL SPECIFICATION - Spécifications techniques

Appearance: Apparence

Off-white to cream lyophilized powder Poudre lyophilisée blanc cassé à crème

Purity (1H NMR): Pureté (1H NMR): Min 95%

Identity (1H NMR): Identité (1H NMR):

Conforms to structure Conforme à la structure

Backbone: Colonne vertébrale: Poly[N-(2-hydroxyethyl)acrylamide-co-N-acrylamide]

Ligand content: Contenu du ligand: 20% mol.

Label: Étiquette

Biotin Biotine

Label content: Contenu de l'étiquette: 5%

DOCUMENT CONTROL - Contrôle des documents

Date of issue: Date d'Emission: 12-NOV-2019

Document ID: ID de document: 0995-BP-SPEC-191112

GlycoNZ Ltd – a subsidiary of Kode Biotech Ltd GlycoNZ Limited PO Box 5965, Wellesley St, Auckland 1141, New Zealand Scott Laboratory Building – AUT University t: (+649) 921 9710 19 Mount St, Auckland, New Zealand

www.GlycoNZ.com

SPECIFICATION Biotinylated polymeric probe (BP)

LN6GalNAcα-C3-PAA-biot LacNAc6Tn polyacrylamide biotin conjugate

_______________________________________________________________________________________

Catalogue ID number: Numéro d'identification du catalogue: 0996-BP

Ligand & spacer: Galβ1-4GlcNAβ1-6GalNAcα-OCH2CH2CH2NH2

Product synonym: Produit synonyme:

LN6GalNAcα-C3-BP LN6GalNAcα-C3-PAA-biot LacNAc6Tn-C3-BP LacNAc6Tn-C3-PAA-biot Galβ1-4GlcNAβ1-6GalNAcα-C3-PAA-biot Galβ1-4GlcNAβ1-6GalNAcα-sp3-PAA-biot Galβ1-4GlcNAβ1-6GalNAcα-OCH2CH2CH2NH2-PAA-biot

Common name of ligand: Nom commun de ligand: LacNAc6Tn

Descriptive name: Nom descriptif:

Poly[N-(2-hydroxyethyl)acrylamide-co-N-(biot-(CH2)5)-acrylamide-co-N-(LN6GalNAcα-C3)-acrylamide]

MW of ligand & spacer: MW de ligand & spacer:

643.6 Da

MW of glycoconjugate: MW de glycoconjugué: ~20 kDa

TECHNICAL SPECIFICATION - Spécifications techniques

Appearance: Apparence

Off-white to cream lyophilized powder Poudre lyophilisée blanc cassé à crème

Purity (1H NMR): Pureté (1H NMR): Min 95%

Identity (1H NMR): Identité (1H NMR):

Conforms to structure Conforme à la structure

Backbone: Colonne vertébrale: Poly[N-(2-hydroxyethyl)acrylamide-co-N-acrylamide]

Ligand content: Contenu du ligand: 20% mol.

Label: Étiquette

Biotin Biotine

Label content: Contenu de l'étiquette: 5%

DOCUMENT CONTROL - Contrôle des documents

Date of issue: Date d'Emission: 12-NOV-2019

Document ID: ID de document: 0996-BP-SPEC-191112

GlycoNZ Ltd – a subsidiary of Kode Biotech Ltd GlycoNZ Limited PO Box 5965, Wellesley St, Auckland 1141, New Zealand Scott Laboratory Building – AUT University t: (+649) 921 9710 19 Mount St, Auckland, New Zealand

www.GlycoNZ.com

SPECIFICATION Biotinylated polymeric probe (BP)

6`SLN-C3-PAA-biot 6'-Sialyllactosamine polyacrylamide biotin conjugate

_______________________________________________________________________________________

Catalogue ID number: Numéro d'identification du catalogue: 0997-BP

Ligand & spacer: Neu5Acα2-6Galβ1-4GlcNAcβ-OCH2CH2CH2NH2

Product synonym: Produit synonyme:

6`SLN-C3-BP 6`SLN-C3-PAA-biot Neu5Acα2-6Galβ1-4GlcNAcβ-C3-PAA-biot Neu5Acα2-6Galβ1-4GlcNAcβ-sp3-PAA-biot Neu5Acα2-6Galβ1-4GlcNAcβ-OCH2CH2CH2NH2-PAA-biot

Common name of ligand: Nom commun de ligand: 6'-Sialyllactosamine, 6`SLN

Descriptive name: Nom descriptif:

Poly[N-(2-hydroxyethyl)acrylamide-co-N-(biot-(CH2)5)-acrylamide-co-N-(6`SLN-C3)-acrylamide]

MW of ligand & spacer: MW de ligand & spacer:

731.7 Da

MW of glycoconjugate: MW de glycoconjugué: ~20 kDa

TECHNICAL SPECIFICATION - Spécifications techniques

Appearance: Apparence

Off-white to cream lyophilized powder Poudre lyophilisée blanc cassé à crème

Purity (1H NMR): Pureté (1H NMR): Min 95%

Identity (1H NMR): Identité (1H NMR):

Conforms to structure Conforme à la structure

Backbone: Colonne vertébrale: Poly[N-(2-hydroxyethyl)acrylamide-co-N-acrylamide]

Ligand content: Contenu du ligand: 20% mol.

Label: Étiquette

Biotin Biotine

Label content: Contenu de l'étiquette: 5%

DOCUMENT CONTROL - Contrôle des documents

Date of issue: Date d'Emission: 12-NOV-2019

Document ID: ID de document: 0997-BP-SPEC-191112

GlycoNZ Ltd – a subsidiary of Kode Biotech Ltd GlycoNZ Limited PO Box 5965, Wellesley St, Auckland 1141, New Zealand Scott Laboratory Building – AUT University t: (+649) 921 9710 19 Mount St, Auckland, New Zealand

www.GlycoNZ.com

SPECIFICATION Biotinylated polymeric probe (BP)

6-suGalNAcα-C3-PAA-biot α-D-GalNAc-6-O-sulfate polyacrylamide biotin conjugate

_______________________________________________________________________________________

Catalogue ID number: Numéro d'identification du catalogue: 0998-BP

Ligand & spacer: 6-O-Su-GalNAcα-OCH2CH2CH2NH2

Product synonym: Produit synonyme:

6-suGalNAcα-C3-BP 6-suGalNAcα-C3-PAA-biot α-D-GalNAc-6-O-sulfate-C3-BP α-D-GalNAc-6-O-sulfate-C3-PAA-biot 6-O-Su-GalNAcα-C3-PAA-biot 6-O-Su-GalNAcα-sp3-PAA-biot 6-O-Su-GalNAcα-OCH2CH2CH2NH2-PAA-biot

Common name of ligand: Nom commun de ligand: α-D-GalNAc-6-O-sulfate

Descriptive name: Nom descriptif:

Poly[N-(2-hydroxyethyl)acrylamide-co-N-(biot-(CH2)5)-acrylamide-co-N-(6-suGalNAcα-C3)-acrylamide]

MW of ligand & spacer: MW de ligand & spacer:

358.4 Da

MW of glycoconjugate: MW de glycoconjugué: ~20 kDa

TECHNICAL SPECIFICATION - Spécifications techniques

Appearance: Apparence

Off-white to cream lyophilized powder Poudre lyophilisée blanc cassé à crème

Purity (1H NMR): Pureté (1H NMR): Min 95%

Identity (1H NMR): Identité (1H NMR):

Conforms to structure Conforme à la structure

Backbone: Colonne vertébrale: Poly[N-(2-hydroxyethyl)acrylamide-co-N-acrylamide]

Ligand content: Contenu du ligand: 20% mol.

Label: Étiquette

Biotin Biotine

Label content: Contenu de l'étiquette: 5%

DOCUMENT CONTROL - Contrôle des documents

Date of issue: Date d'Emission: 12-NOV-2019

Document ID: ID de document: 0998-BP-SPEC-191112