Standardisation: study-based meta data

CRS Webinar

Processes

5 main processes involved in maintaining my study-based register

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Main processes

…4 (and a tenth) now happen in the CRS

Studify

Studification

Attempt to group related records together

Code new studies

Confirm grouping of related records was correct. Amend

as necessary

This webinar

‘Coding’

• Extracting details about a study to populate a study form

What details should I extract?

Study fields used by the dementia group 1

Field Type of field

Study name (SN) Text

Study full name (SFN) Text

Study acronym (SA) Text

Study registration ID (SID)

Text

URL to study registration (SUR)

URL

Other study number (SON)

Text

The first set of fields are about identification

Study fields used by the dementia group 2

Field Type of field

Status of study (SS) Pick

Status of study information (SSI)

Pick

Study protocol available (SPA)

Pick

Start date of study (SSD) Text

Expected end date of study (SXD)

Text

End date of study (SED) Text

Study results publication date (RP)

Text

The next set of fields are about Status of trial

Study fields used by the dementia group 3Field Type of field

Study design Pick

Blinding Pick

Intervention type (IT) Pick

Intervention/s (SIN) Seed

Dosage and duration (DD) Text

Participants (size) (SSZ) Text

Healthcare condition (SCO) Text

Comorbid healthcare condition (SCM) Text

Unit of allocation (UA) Pick

Country of origin of study (SOS)

The next set of fields are about Characteristics

PICO

Study fields used by the dementia group 4

Field Type of field

ALOIS status Pick

ALOIS tags (TG) Seed

ALOIS study name Text

Related Cochrane review

Seed

The next set of fields are more Admin and New

Field Type of field

Funding type Pick

Funding source Text

ADMIN

NEW

Example queries

• Show me all trials which have been funded by industry AND are completed but have not yet published

CRS search string:

#1 industry:FT

#2 completed:SS

#3 results not available:SSI

#4 #1 AND #2 AND #3

Discussion

• ClinicalTrials.gov study form – makes sense to use the same?

• WHO portal – 20 pieces of study metadata –use that?

• Controlled vocabs – MeSH, Emtree, others –use those?

• Linked data project – implications?

• RevMan Characteristics of included studies

ClinicalTrials.gov

WHO portal/ICTRP