stanford bio-x interdisciplinary initiatives seed grants ... · 26 uncovering the hidden role of...

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POSTER # TITLE AUTHORS 1 Antibodies Against Pf Phage Prevent Pseudomonas aeruginosa Wound Infections by Promoting Phagocytosis Michelle Bach 1 , Jolien Sweere 1 , Heather Ishak 1 , Gina Suh 1 , Paul Bollyky 1 Department of Medicine (Division of Infectious Diseases 1 ), Stanford University 2 Visualizing Neuronal Release of Sonic Hedgehog in Taste Receptor Cell Regeneration Ankit Baghel 1 , Wan-Jin Lu 1 , Philip Beachy 1,2,3 Department of Biochemistry 2 , Institute for Stem Cell Biology & Regenerative Medicine 1 , and Howard Hughes Medical Institute 3 , Stanford University 3 Deep Learning-Driven Protein-Protein Docking Rishi Bedi 1 , Raphael Townshend 1 , João Rodrigues 2 , Ron Dror 1 Departments of Computer Science 1 and Structural Biology 2 , Stanford University 4 NIRS Neurofeedback for Improving Executive Function in Children with ADH Sarah Bell 1 , Hadi Hosseini 1 , Allan Reiss 1 Department of Psychiatry & Behavioral Sciences 1 , Stanford University 5 Elucidating the Biological Targets and Pathways of Novel Drugs in Breast Cancer Alisha Birk 1 , Catherine Going 1 , Vineet Kumar 2 , Sanjay Malhotra 2 , Sharon Pitteri 1 Departments of Radiology 1 and Radiation Oncology 2 , Stanford University 6 Early Steps Towards Automating Surgical Tasks Through Physics and Soft-Body Simulation Alexandra Bourdillon 1 , Animesh Garg 2 , Hanjay Wang 1 , Jack Boyd 1 , Marco Pavone 3 , Joseph Woo 1 Departments of Cardiothoracic Surgery 1 , Computer Science 2 , and Aeronautics & Astronautics 3 , Stanford University 7 MicroRNA Regulation of Neuronal Mitochondrial Function During Oxidative Stress Ryan Buchanan 1 , Anand Rao 1 , Georgia Kaidonis 1 , Xiaoyun Sun 1 , Creed Stary 1 Department of Anesthesia 1 , Stanford University 8 Dissecting Mechanisms of Drug Action by Structure-Function Mapping with CRISPR Saturation Editing of Amino Acids Tucker Burnett 1 , Kevin Roy 2 , Justin Smith 2,3 , Maddison Morgan 4 , Julia Schulz 5 , Kevin Orsley 6 , Lars Steinmetz 2 , Bob St. Onge 3 , Ron Davis 2,3 Departments of Chemistry 1 , Genetics 2 , Biochemistry 3 , and Bioengineering 5 , Stanford University; Department of Biology 4 , Middlebury College; Department of Biology 6 , Emmanuel College 9 Targeting CREB for Novel AML Therapies Tae-León Butler 1,2 , Justin Chan 1,2 , Hee-Don Chae 1,2 , Kathleen Sakamoto 1,2 Departments of Pediatrics 1 and Medicine (Division of Hematology & Oncology 2 ), Stanford University 10 Improving the Efficiency of Homologous Recombination in High- Throughput CRISPR Editing in Saccharomyces cerevisiae Julia Schulz 1 , Justin D. Smith 2,3 , Kevin Roy 2 , Maddison Morgan 4 , Tucker Burnett 5 , Kevin Orsley 6 , Sundari Suresh 3 , Angela Chu 3 , Ron Davis 2,3 , Bob St. Onge 3 , Lars Steinmetz 2 Departments of Bioengineering 1 , Genetics 2 , Biochemistry 3 , and Chemistry 5 , Stanford University; Department of Biology 4 , Middlebury College; Department of Biology 6 , Emmanuel College 11 Aging-Induced Neurodegeneration in the African Turquoise Killifish Sharon Chen 1 , Andrew McKay 1 , Anne Brunet 2 Departments of Biology 1 and Genetics 2 , Stanford University Stanford Bio-X Interdisciplinary Initiatives Seed Grants Symposium Poster Session August 24, 2017

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Page 1: Stanford Bio-X Interdisciplinary Initiatives Seed Grants ... · 26 Uncovering the Hidden Role of Ribosomes in Mammalian Development ... Sophie M. Rose1, Robin A. Libove2, ... Jordan

POSTER # TITLE AUTHORS

1 Antibodies Against Pf Phage Prevent Pseudomonas aeruginosa Wound

Infections by Promoting Phagocytosis

Michelle Bach1, Jolien Sweere1, Heather Ishak1,

Gina Suh1, Paul Bollyky1

Department of Medicine (Division of Infectious

Diseases1), Stanford University

2 Visualizing Neuronal Release of Sonic Hedgehog in Taste Receptor Cell

Regeneration

Ankit Baghel1, Wan-Jin Lu1, Philip Beachy1,2,3

Department of Biochemistry2, Institute for Stem

Cell Biology & Regenerative Medicine1, and

Howard Hughes Medical Institute3, Stanford

University

3 Deep Learning-Driven Protein-Protein Docking

Rishi Bedi1, Raphael Townshend1, João

Rodrigues2, Ron Dror1

Departments of Computer Science1 and Structural

Biology2, Stanford University

4 NIRS Neurofeedback for Improving Executive Function in Children with

ADH

Sarah Bell1, Hadi Hosseini1, Allan Reiss1

Department of Psychiatry & Behavioral

Sciences1, Stanford University

5 Elucidating the Biological Targets and Pathways of Novel Drugs in

Breast Cancer

Alisha Birk1, Catherine Going1, Vineet Kumar2,

Sanjay Malhotra2, Sharon Pitteri1

Departments of Radiology1 and Radiation

Oncology2, Stanford University

6 Early Steps Towards Automating Surgical Tasks Through Physics and

Soft-Body Simulation

Alexandra Bourdillon1, Animesh Garg2, Hanjay

Wang1, Jack Boyd1, Marco Pavone3, Joseph Woo1

Departments of Cardiothoracic Surgery1,

Computer Science2, and Aeronautics &

Astronautics3, Stanford University

7 MicroRNA Regulation of Neuronal Mitochondrial Function During

Oxidative Stress

Ryan Buchanan1, Anand Rao1, Georgia Kaidonis1,

Xiaoyun Sun1, Creed Stary1

Department of Anesthesia1, Stanford University

8 Dissecting Mechanisms of Drug Action by Structure-Function Mapping

with CRISPR Saturation Editing of Amino Acids

Tucker Burnett1, Kevin Roy2, Justin Smith2,3,

Maddison Morgan4, Julia Schulz5, Kevin Orsley6,

Lars Steinmetz2, Bob St. Onge3, Ron Davis2,3

Departments of Chemistry1, Genetics2,

Biochemistry3, and Bioengineering5, Stanford

University; Department of Biology4, Middlebury

College; Department of Biology6, Emmanuel

College

9 Targeting CREB for Novel AML Therapies

Tae-León Butler1,2, Justin Chan1,2, Hee-Don

Chae1,2, Kathleen Sakamoto1,2

Departments of Pediatrics1 and Medicine

(Division of Hematology & Oncology2), Stanford

University

10 Improving the Efficiency of Homologous Recombination in High-

Throughput CRISPR Editing in Saccharomyces cerevisiae

Julia Schulz1, Justin D. Smith2,3, Kevin Roy2,

Maddison Morgan4, Tucker Burnett5, Kevin

Orsley6, Sundari Suresh3, Angela Chu3, Ron

Davis2,3, Bob St. Onge3, Lars Steinmetz2

Departments of Bioengineering1, Genetics2,

Biochemistry3, and Chemistry5, Stanford

University; Department of Biology4, Middlebury

College; Department of Biology6, Emmanuel

College

11 Aging-Induced Neurodegeneration in the African Turquoise Killifish

Sharon Chen1, Andrew McKay1, Anne Brunet2

Departments of Biology1 and Genetics2, Stanford

University

Stanford Bio-X Interdisciplinary Initiatives Seed Grants Symposium

Poster Session August 24, 2017

Page 2: Stanford Bio-X Interdisciplinary Initiatives Seed Grants ... · 26 Uncovering the Hidden Role of Ribosomes in Mammalian Development ... Sophie M. Rose1, Robin A. Libove2, ... Jordan

12 Optimizing Super-Resolution Microscopy to Visualize Chromatin

Conformation of Cis-Regulatory Elements During Development

Zack Cinquini1, Leslie Mateo2, Alistair Boettiger2

Departments of Computer Science1 and

Developmental Biology2, Stanford University

13 The Consolidation of Memory: An Analysis of Cortical Circuits Involved

in Remote Memory Retrieval

Kendall Costello1, Laura DeNardo1, Cindy Liu1,

Eliza Adams1, Will Allen1, Liqun Luo1,2

Department of Biology1 and Howard Hughes

Medical Institute2, Stanford University

14 Automatic Phenotype Extraction from Medical Records

Cole A. Deisseroth1, Johannes Birgmeier1,

Jonathan A. Bernstein2, Gill Bejerano1

Departments of Developmental Biology1 and

Pediatrics2, Stanford University

15 Modulating Visual Sensitivity with Transcranial Electrical Stimulation

Jorge Delgado1, Guillaume Riesen1, Molly

Lucas2, Anthony Norcia1

Departments of Psychology1 and Neuroscience2,

Stanford University

16 Impact of Recurrent Seizures on Myelin Plasticity in a Rat Model of

Absence Epilepsy

Eleanor Frost1, Juliet Knowles1, Michelle Monje1

Department of Neurology & Neurological

Sciences1, Stanford University

17 Multimodal Imaging of the FMR1 Knockout Mouse: A Model of Fragile

X Syndrome

Scarlett Guo1, Samantha Reyes1, Bin Shen1,

Shawn Scatliffe1, Jun Hyung Park1, Zheng Miao1,

Jessa Castillo1, Sanaz Mohajeri1, Meng Gu1,

Christoph Leuze1, Frederick T. Chin1

Department of Radiology1, Stanford University

18 Genetic Determinants of Physical Activity

David Amar3, Daryl Waggott3, David Hsu1,3,

Anna Shcherbina2, Euan Ashley2,3 Departments of Biology1 and Medicine (Division

of Cardiovascular Medicine3) and Program in

Biomedical Informatics2, Stanford University

19 3D Printing of Vascular Architecture for Myocardial Tissue Constructs

James Hu1, Vahid Serpooshan1, Ken Hinh1, Ryan

Ferdowsian1, Sean Wu1,2,3

Stanford Cardiovascular Institute1, Institute for

Stem Cell Biology & Regenerative Medicine2,

and Department of Medicine (Division of

Cardiovascular Medicine3), Stanford University

20 Robust Cancer Image Feature Discovery through Novel Digital Phantoms

Akshay Jaggi1, Sebastian Echergay1, Shaimaa

Bakr2, Sandy Napel1

Departments of Radiology1 and Electrical

Engineering2, Stanford University

21 Single-Cell Ribo-Seq via Affinity Purification

Mika Jain1, Stephen Quake2

Departments of Computer Science1 and

Bioengineering2, Stanford University

22 Characterization of Novel Cell Lines Isolated from Human Brain

Arteriovenous Malformations (AVMs)

Ketan Jain-Poster1, Lorelei Shoemaker1, Breanna

Allen1, Steven Chang1

Department of Neurosurgery1, Stanford

University

23 SNARE Proteins as Antagonistic Regulators of KRAS

Tiffany Jiang1,2, Yonglu Che3, Paul Khavari4

Departments of Music1, Biology2, Cancer

Biology3, and Dermatology4, Stanford University

24 c-Jun, a New Player in Regulating Bone Mass, as a Clinical Target for

the Treatment of Osteopenic Disease

Yong-hun Kim1*, Tristan Lerbs1*, Camille Van

Neste1, Gerlinde Wernig1

(*equal contribution) Department of Pathology1,

Stanford University

25 Effects of Categorization on the Other-Race Effect

Hee Joo Ko1, Annabelle Tao1, Jennifer Yih1, Omri

Raccah,1 Josef Parvizi1

Department of Neurology & Neurological

Sciences1, Stanford University

26 Uncovering the Hidden Role of Ribosomes in Mammalian Development

Pallavi Krishnarao1,4, Gerald Tiu2, Maria Barna2,3

Departments of Biology1, Genetics2, and

Developmental Biology3 and Symbolic Systems

Program4, Stanford University

27 Identification of Novel Interactions Between Astrocytic Neurexin-1 and

Synaptic Ligands

Jason Li1,2, Justin Trotter3, Thomas Südhof3

Departments of Computer Science1, Biology2, and

Molecular & Cellular Physiology3, Stanford

University

Page 3: Stanford Bio-X Interdisciplinary Initiatives Seed Grants ... · 26 Uncovering the Hidden Role of Ribosomes in Mammalian Development ... Sophie M. Rose1, Robin A. Libove2, ... Jordan

28 A Novel Method to Fabricate 3D Gradient Hydrogels with Clinically

Relevant Dimensions for Cartilage Repair

Elisa Liu1, Danqing Zhu1, Fan Yang1, 2

Departments of Bioengineering1 and Orthopaedic

Surgery2, Stanford University

29 Discovering Agonist Nanobodies to Muscle Stem Cell GPCRS for Use as

Therapeutic Biologics

Helen Liu1,2,3, David M. Burns1,2,3, Helen Blau1,2,3

Baxter Laboratory for Stem Cell Biology1,

Department of Microbiology & Immunology2,

and Institute for Stem Cell Biology &

Regenerative Medicine3, Stanford University

30 Validation Studies of Live Cell Array-Derived Markers to Identify

Cancer Stem Cells in GBM

Cindy Liu1, Hai Li1, Stephen Skirboll1

Department of Neurosurgery1, Stanford

University

31 Investigating the Role of Gpr126 and cAMP in Schwann Cells

Hannah Llorin1, Mariapaola Sidoli1, William

Talbot1

Department of Developmental Biology1, Stanford

University

32 Patient-Specific Blood Flow Simulations of Kawasaki Disease for

Thrombotic Risk Stratification

Alexander Lu1, Noelia G. Grande2, Alison L.

Marsden3,4,5

Departments of Mechanical Engineering2,

Bioengineering3, Cardiology (Division of

Pediatric Cardiology5), Institute for

Computational & Mathematical Engineering4, and

Biomedical Computation Program1, Stanford

University

33 Examining Arrhythmogenic Indicators: Advanced Portable Telemetry for

Monitoring Post-Operational Atrial Fibrillation

Jonathan Jia-An Mak1, Cody Carlton2, Miguel

Rodrigo3, Joy Aparicio Valenzuela4, Xinyuan

Zhang4, Patrick D. Loftus4, Anson Lee4

Departments of Electrical Engineering1,

Computational Biology2, Cardiovascular

Medicine3, and Cardiothoracic Surgery4, Stanford

University

34 Investigating the Role of CDPC1 and CD47 in Metastatic Prostate

Cancer Immune Evasion and Tumorigenesis

Anoop Manjunath1, Gunsagar S. Gulati2, Rosalynd

Upton2, Elly Seo3, Owen Marecic3, Michael

Lopez3, Jun Seita4, Debashis Sahoo5, Anne

Leyrat6, Michael Gonzales6, Norma Neff7,

Sopheak Sim4, Stephen Quake7, Michael T.

Longaker3, Charles K. F. Chan3, Irving L.

Weissman8,9 Departments of Biology1, Cancer Biology2,

Surgery3, Bioengineering7, Pathology8, and

Developmental Biology9 and Institute for Stem

Cell Biology & Regenerative Medicine4, Stanford

University; Department of Pediatrics5, University

of California, San Diego; Fluidigm Corporation6

35 Effect of Intranasal Oxytocin on Contagious Response to Yawning and

Laughter in Children with Autism

Michael G. Mariscal1, Sophie M. Rose1, Robin A.

Libove2, Antonio Y. Hardan2, Karen J. Parker2

Departments of Human Biology1 and Psychiatry

& Behavioral Sciences2, Stanford University

36 Divided Attention’s Effect on Flexible Prospection During Navigation

Sarah Matsunaga1, Stephanie Gagnon2, Thackery

Brown3, Anthony Wagner2

Departments of Human Biology1 and

Psychology2, Stanford University; School of

Psychology3, Georgia Institute of Technology

37 Localizing Origins of the Essential Tremor Phenotype in a Novel Mouse

Model

Max Melin1, Mu Zhou1, Thomas C. Sudhof1,2,3

Departments of Molecular & Cellular

Physiology1, Neurology2, and Psychiatry &

Behavioral Sciences3, Stanford University

38 Determining the Role of VCAM1+ Brain Endothelial Cells in Mediating

Neuroinflammation and Brain Aging

Taylor Merkel1, Hanadie Yousef1, Davis Lee2,

Tony Wyss-Coray1,2

Department of Neurology & Neurological

Sciences1, Stanford University; VA Palo Alto

Health Care System2, Palo Alto

39 Characterization of the p53 Tumor Suppressor Protein-Protein

Interactions Identified by Affinity Purification and Mass Spectrometry

Clare Moffatt1, Nitin Raj1, Nancie Moonie2, Janos

Demeter2, Ahlima Roumane1, Sara Sakowitz1,

Peter Jackson2, Laura Attardi1

Page 4: Stanford Bio-X Interdisciplinary Initiatives Seed Grants ... · 26 Uncovering the Hidden Role of Ribosomes in Mammalian Development ... Sophie M. Rose1, Robin A. Libove2, ... Jordan

Departments of Radiation Oncology1 and

Microbiology & Immunology2, Stanford

University

40 Novel Parallel Computing Methods for Fitting Neuronal Network Models

to Experimental Data

Grace Ng1, Aaron Milstein1, Ivan Raikov1, Ivan

Soltesz1

Department of Neurosurgery1, Stanford

University

41 Appropriation of Tissue Renewal Signals Drives Development of

Intestinal Stem Cell Adenomas

Sang Ngo1, Jackson Liang2, Lucy O’Brien1

Department of Molecular & Cellular Physiology1,

Stanford University; Genentech, Inc.2

42 Human Chromatin Reorganization Using a CRISPR/dCas9-Based

Dimerization System

Cindy Nguyen1, Haifeng Wang1, Stanley Qi1

Department of Bioengineering1, Stanford

University

43 Sex Differences in White Matter Tract Development Across Puberty

Kira Oskirko1, Tiffany Ho1, Natalie Colich1, Ian

Gotlib1

Department of Psychology1, Stanford University

44 Generating in vitro Models of HER2 Positive Gastric Cancer from Patient

Derived Normal Tissue

Enoch Park1, Amanda Mah1, Calvin Kuo1

Department of Hematology1, Stanford University

45 Understanding the Roles of AP2A and P63 in Guiding Non-Neural

Ectoderm Cell Commitment

Jennifer Parker1, Jillian Pattison2, Jessica

Torkelson2, Sandra Carlos2, Anthony Oro2

Department of Biology1 and Dermatology2,

Stanford University

46 The Effect of Augmented Reality on Gait in Parkinson’s Disease

Jordan Parker1, Johanna O’Day2, Russell

Mendonca1, Chioma Anidi1, Helen Bronte-

Stewart1

Departments of Neurology & Neurological

Sciences1 and Bioengineering2, Stanford

University

47 The Effects of the Heterozygous 16p11.2 Deletion on Cell Proliferation

in the Embryonic Brain

Tess Rinaldo1, Brooke Babineau1, Aditi Narayan1,

Michelle Kielhold1, Amy Moon1, Theo Palmer1

Department of Neurosurgery1, Stanford

University

48 Photogrammetry for Morphological Analysis of African Cichlids

Maricela Sistos1, Sebastian Alvarado1, Russell

Fernald1

Department of Biology1, Stanford University

49 Project SERVE: An Insomnia Clinical Trial for Military Veterans

Gia Paige Soles1,2, Alan F. Schatzberg1, Steven E.

Lindley3, Rebecca Ann Bernert1,2

Department of Psychiatry & Behavioral Sciences1

and Suicide Prevention Research Laboratory2,

Stanford University; VA Palo Alto Health Care

System3, Menlo Park Division

50 The Role of GCNT1 in Prostate Cancer Development

Austin Su3, En-Chi Hsu1, Meghan Rice1, Mark

Buckup3, Rosalie Nolley2, James Brooks2, Donna

Peehl2, Tanya Stoyanova1

Departments of Radiology1, Urology2, and

Biology3, Stanford University

51 Activity-Dependent Investigation of Insular Cortex Circuitry Dynamics

Daniel Tang1, Brian Hsueh3,4, Li Ye2,5, Josh

Jennings1, Karl Deisseroth1,2,5

Departments of Bioengineering1 and Psychiatry &

Behavioral Sciences2, Neurosciences Program3,

Medical Scientist Training Program4, and Howard

Hughes Medical Institute5, Stanford University

52 Genetic and Functional Dissection of Neural Circuits: Decoding

Motivational Drives

Nicole Sabina Ticea1, Ethan Richman2, Karl

Deisseroth1,3, Liqun Luo4

Departments of Bioengineering1, Psychiatry &

Behavioural Sciences3, and Biology4 and

Neurosciences Program2, Stanford University

53 Inhibition of the Ribosomal S6 Kinase Causes Cell Cycle Arrest and

Apoptosis in Acute Myeloid Leukemia Cells

Bruce Tiu1, Hee-Don Chae1, Ritika Dutta1,

Kathleen Sakamoto1

Department of Pediatrics1, Stanford University

54 The Role of Reactive Astrocytes in the Surrounding Microenvironment

of Brain Metastases

Kevin Tran1, Sophia Chernikova1, Ian Connolly1,

Eli Johnson1, Bina Kakusa1, Lina Khoeur1,

Yingmei Li1, Dina Polyak1, Melanie G. Hayden

Gephart1

Page 5: Stanford Bio-X Interdisciplinary Initiatives Seed Grants ... · 26 Uncovering the Hidden Role of Ribosomes in Mammalian Development ... Sophie M. Rose1, Robin A. Libove2, ... Jordan

Department of Neurosurgery1, Stanford

University

55 Synthesis of Solvatochromic Probes to Label the Mycobacterial Cell

Wall

Ashley Utz1, Samantha G. L. Keyser2,4, Mireille

Kamariza1, Aidan Pezacki3,4, Carolyn R.

Bertozzi4,5

Departments of Biology1 and Chemistry4 and

Howard Hughes Medical Institute5, Stanford

University; Department of Chemistry2, University

of California, Berkeley; Department of Chemistry

& Biomolecular Sciences3, University of Ottawa,

Canada

56 Effects of Tumor Irradiation on Circulating Macraophage Localization

Jonathan Wang1, Stavros Melemenidis1, Laura

Bronsart1, Luis Soto2, Ysaman Ahrari1, Edward

Graves1

Department of Radiation Oncology1 and Cancer

Biology2, Stanford University

57 Developmental Expression of the Non-Classical MHC1 Qa-1, a

Regulator of Visual Plasticity

Alan Y. Wei1, Ioana A. Marin1, Kylie S. Chew1,

Carla J. Shatz1,2

Departments of Biology1 and Neurobiology2,

Stanford University

58 Tissue-Restricted Redundancy of Adenylate Kinases 1 and 2 Explains

SCID-Phenotype in Reticular Dysgenesis (AK2 Deficiency)

Ashley Westerfield1, Avni Awani1, Katja

Weinacht1

Department of Pediatrics1, Stanford University

59 Understanding the Role of the Gene C2orf54 in the Epidermal

Differentiation Process

Kamina Wilkerson1, Angela Peralta1, Dane

Sessions1, Carolyn Lee1

Department of Dermatology1, Stanford University

60 How to Feed a Cancer Cell: The KRAS Gene and Macropinocytosis

David Wu1, Marcus Kelly1,2, Peter K. Jackson1,3

Departments of Immunology & Microbiology1

and Cancer Biology2 and Baxter Laboratory for

Stem Cell Biology3, Stanford University

61 T2, T2*, and T1ρ Variations of Cartilage Imaged in Four ex-vivo

Environments

Michelle Xiao1, Marianne S. Black1,2, Garry E.

Gold2,3, Brian A. Hargreaves2,3, Marc E.

Levenston1,2,3

Departments of Mechanical Engineering1,

Radiology2, and Bioengineering3, Stanford

University

62 Modeling Kinetics of GLP1R-Mediated Peptide-Based Drug Delivery

Benjamin Yeh1, Tim Horton2, Justin Annes3

Departments of Bioengineering1, Chemistry2, and

Medicine (Division of Endocrinology3), Stanford

University

63 Kinetics of Contrast Agents Extravasation Across the Blood Brain

Barrier After Focused Ultrasound Opening

Victoria Yuan1,2, Aurea Pascal-Tenorio1,2, Kim

Butts Pauly1,2

Department of Radiology1 and Radiological

Sciences Laboratory2, Stanford University

64 Investigating NAA10 Mutation-Based Cardiac Dysfunction Using

Human iPSC Disease Modeling

Sophia Zhang1, Ning Ma1, Joseph Wu1

Department of Medicine (Stanford Cardiovascular

Institute1), Stanford University

65

Multi-Scale Matrix Mechanics in Breast Cancer Models Revealed by

Dynamic Light Scattering Microrheology: At the Intersection of Biology

and Polymer Physics

Audrey Zhu1, Brad Krajina1, Sarah Heilshorn2

Departments of Chemical Engineering1 and

Materials Science & Engineering2, Stanford

University

66 Mechanisms of Generalist Host Range in the Ectomycorrhizal Symbiosis Laura Bogar1, Kabir Peay1

Department of Biology1, Stanford University

67 Discovery and Engineering of an Anti-Fungal Biosynthetic Pathway from

Edible Plants

Amy Calgaro-Kozina1, Elizabeth Sattely1

Department of Chemical Engineering1, Stanford

University

68 Telomere Shortening as a Hallmark of Lethal Dilated Cardiomyopathy

Alex C.Y. Chang1,2,4,5, Andrew C.H. Chang1,2,4,

Koki Sasagawa1,2,4,5, Anna Kirillova1,2,4,5, Ioannis

Karakikes3,5, Vittavat Termglinchan3,5, Haodi

Wu3,5, Alexandre Ribeiro5,6, Willis Su1,2,4, Edward

LaGory7, Amato Giaccia7, Beth Pruitt5,6, John W.

Day8, Joseph C. Wu3,5, Helen M. Blau1,5

Baxter Laboratory for Stem Cell Biology1,

Departments of Microbiology & Immunology2,

Page 6: Stanford Bio-X Interdisciplinary Initiatives Seed Grants ... · 26 Uncovering the Hidden Role of Ribosomes in Mammalian Development ... Sophie M. Rose1, Robin A. Libove2, ... Jordan

Medicine (Division of Cardiology3), Mechanical

Engineering6, Radiation Oncology (Division of

Radiation & Cancer Biology7), and Neurology8,

Institute for Stem Cell Biology & Regenerative

Medicine4, and Stanford Cardiovascular Institute5,

Stanford University

69 Hydroxyapatite Coated Microribbon-Based Hydrogels Induce Robust

Osteogenesis and Mineralization of Mesenchymal Stem Cells in 3D

Bogdan Conrad1, Xinming Tong2, Fan Yang2,3

Departments of Orthopaedic Surgery2 and

Bioengineering3 and Institute for Stem Cell

Biology & Regenerative Medicine1, Stanford

University

70 The Fatty Acid Elongase EloF Is a Major Driver in the Sexual Isolation

of Drosophila simulans and Drosophila sechellia

Peter Combs1, Joshua Krupp2, Neil Khosla1,

Dennis Bua1, Joel Levine2, Hunter Fraser1

Department of Biology1, Stanford University;

Department of Biology2, University of Toronto

71 Shape-Aware Spatio-Temporal Descriptors for Interaction Classification

Soeren Pirk1, Olga Diamanti1, Boris Thibert1,

Danfei Xu1, Leonidas Guibas1

Department of Computer Science1, Stanford

University

72 Stable Region Correspondences Between Non-Isometric Shapes

Vignesh Ganapathi-Subramanian1, Boris

Thibert2,4, Maks Ovsjanikov3, Leonidas J. Guibas2

Departments of Electrical Engineering1 and

Computer Science2, Stanford University; École

Polytechnique3, Université Paris-Saclay;

Université Grenoble Alpes4

73 Using Handheld Stereo Depth Cameras to Extend Medical Imaging for

Radiation Therapy Planning

Cesare Jenkins1,2, Shu-Jung Yu1, Lei Xing1

Departments of Radiation Oncology1 and

Mechanical Engineering2, Stanford University

74 Metabolomics and Transcriptomics Implicate Acetylenic Compounds in

Plant-Pathogen Interactions

Ju Eun Jeon1,2, Mary Beth Mudgett1, Elizabeth

Sattely2

Departments of Biology1 and Chemical

Engineering2, Stanford University

75 The Influence of Protein-Surfactant Interfacial Co-Adsorption on Thin

Film Drainage and Bubble Coalescence

Aadithya Kannan1, Ian C. Shieh2, Danielle L.

Leiske2, Nikhil Sethia1, Camila Kofman1, Gerald

G. Fuller1

Department of Chemical Engineering1, Stanford

University; Genentech Inc.2

76 Single-Cell Imaging Using Radioluminescence Microscopy Reveals

Unexpected Binding Pattern of [18F] HFB

Louise Kiru1, Tae Jin Kim1, Bin Shen2, Frederick

T. Chin2, Guillem Pratx1

Departments of Radiation Oncology1 and

Radiology2, Stanford University

77 Maintenance of Neural Progenitor Cell Stemness in 3D Hydrogels

Requires Matrix Remodeling

Christopher M. Madl1, Ruby E. Dewi2, Cong

Dinh2, Kyle J. Lampe2,3, Duong Nguyen4, Annika

Enejder4,5, Sarah C. Heilshorn2

Departments of Bioengineering1 and Materials

Science & Engineering2, Stanford University;

Department of Chemical Engineering3, University

of Virginia; Departments of Biology4 and

Biological Engineering5, Chalmers University of

Technology, Gothenburg Sweden

78 A Programmable Alternative Splicing Platform for Regulating Protein

Diversity

Melina Mathur1, Cameron Kim1, Sarah Munro2,

Christina D. Smolke1

Department of Bioengineering1, Stanford

University; National Institute of Standards &

Technology2, U.S. Department of Commerce

79 Inactivation and Transcriptional Response of Staphylococcus aureus to

Sunlight Under Oxic and Anoxic Conditions

Jill S. McClary1, Alexandria B. Boehm1

Department of Civil & Environmental

Engineering1, Stanford University

80 Charge-Altering Releasable Transporters (CARTs) for the Delivery and

Release of Messenger-RNA

Colin J. McKinlay1, Jessica R. Vargas1, Timothy

R. Blake1, Jonathan W. Hardy2,7, Masamitsu

Kanada2,7, Christopher H. Contag2,3,4,5,7, Paul A.

Wender1,6, Robert M. Waymouth1 Departments of Chemistry1, Pediatrics2,

Microbiology & Immunology3, Bioengineering4,

Page 7: Stanford Bio-X Interdisciplinary Initiatives Seed Grants ... · 26 Uncovering the Hidden Role of Ribosomes in Mammalian Development ... Sophie M. Rose1, Robin A. Libove2, ... Jordan

Radiology5, and Chemical & Systems Biology6

and Molecular Imaging Program at Stanford

(MIPS)7; Stanford University

81 Optical Control of Neural Ablation in Zebrafish - A Model for CNS

Injury Mechanisms

Karen Mruk1,2, Patrick A. Piza1, Mohammad A.

Alnaqib1, James K. Chen1,2

Departments of Chemical & Systems Biology1

and Developmental Biology2, Stanford University

82 Prostaglandin E2 Is Essential for Efficacious Skeletal Muscle Stem Cell

Function, Augmenting Regeneration and Strength

Adelaida R. Palla1,4,5,*, Andrew T.V. Ho1,4,5*,

Matthew R. Blake1,4,5, Nora D. Yucel1,4,5, Yu Xin

Wang1,4,5, Klas E.G. Magnusson1,2,4,5, Colin A.

Holbrook1,4,5, Peggy Kraft1,4,5, Scott L. Delp3,

Helen M. Blau1,4,5

(*equal contribution) Baxter Laboratory for Stem

Cell Biology1, Departments of Microbiology &

Immunology4 and Bioengineering3, and Institute

for Stem Cell Biology & Regenerative Medicine5,

Stanford University; Department of Signal

Processing2 (ACCESS Linnaeus Centre), KTH

Royal Institute of Technology, Sweden

83 Recurrent Architectures for Annotating Protein Secondary Structural

Elements

Christopher Probert1,2, Aaron Cravens3

Departments of Genetics1, Computer Science2,

and Bioengineering3, Stanford University

84 PointNet: Deep Learning on Point Sets for 3D Classification and

Segmentation

Charles Ruizhongtai Qi1, Hao Su2, Kaichun Mo2,

Leonidas J. Guibas2

Departments of Electrical Engineering1 and

Computer Science2, Stanford University

85 Tumor and Immune Cell Infiltration Are Enhanced by Irradiation of

Normal Tissues in Immunocompromised Mice

Marjan Rafat1, Todd A. Aguilera1, Marta Vilalta1,

Laura L. Bronsart1, Luis A. Soto1, Rie von

Eyben1, Amato J. Giaccia1, Edward E. Graves1

Department of Radiation Oncology1, Stanford

University

86 Using TMS-EEG to Understand the Cortical Circuit Dynamics in Stroke

Camarin Rolle1, Fiona Baumer2,3, Hersh Trivedi4,

Ayesha Nadiadwala4, Karen Monuszko4, Kacey

Berry2, Maarten Lansberg2, Marion Buckwalter2,

Amit Etkin4

Neurosciences Program1, Departments of

Neurology & Neurological Sciences2, Health

Research and Policy3, and Psychiatry &

Behavioral Science4, Stanford University

87 Competition-Colonization Tradeoffs Structure Microbial Diversity

Gabriel R. Smith1, Brian S. Steidinger1, Thomas

D. Bruns2, Kabir G. Peay1

Department of Biology1, Stanford University;

Department of Plant & Microbial Biology2,

University of California, Berkeley

88 Recurrent Neural Network Models to Quantitatively Predict RNA

Interactions

Michelle Wu1, Johan Andreasson2,3, Wipapat

Kladwang3, Will Greenleaf2, Rhiju Das3

Departments of Genetics2 and Biochemistry3 and

Program in Biomedical Informatics1, Stanford

University

89 Advancing RNA Device Engineering with Data-Rich Strategies and

Automation

Joy S. Xiang1, Brent Townshend1, Michaela

Hinks1, Gabriel Manzanarez1, Christina D.

Smolke1

Department of Bioengineering1, Stanford

University

90 Imaging the Cardiac Field Potential via Graphene Optoelectronics

Allister F. McGuire1, Halleh B. Balch2, Jason

Horng2, Hsin-Zon Tsai2, Patrick R. Forrester2,

Michael F. Crommie2, Feng Wang2, Bianxiao

Cui1

Department of Chemistry1, Stanford University;

Department of Physics2, University of California,

Berkeley

91 Tissue Architecture Coordinates Differentiation and Apical Emergence in

the Drosophila Midgut Epithelium

Paola Moreno-Roman1, Irina Kolotueva3, Bruno

Humbel3, Lucy Erin O’Brien2

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Departments of Bioengineering1 and Molecular &

Cellular Physiology2, Stanford University; Electron Microscopy Facility3, Université de

Lausanne

92 Engineering Beneficial Plant-Microbe Interactions for Improved Crop

Drought Tolerance

Tim Schnabel1, Elizabeth Sattely2

Departments of Bioengineering1 and Chemical

Engineering2, Stanford University

93 Towards Engineered Plant-Microbe Symbioses

Mathias J. Voges1,2, Yang Bai3, Ruben G. Oter3,

Masayoshi Hashimoto3, Paul Schulze-Lefert3,

Elizabeth S. Sattely2

Departments of Bioengineering1 and Chemical

Engineering2, Stanford University; Department of

Plant Microbe Interactions3, Max Planck Institute

for Plant Breeding Research, Germany

94 Quantitative Contrast-Enhanced Optical Coherence Tomography

Yonatan Winetraub1,3,4,5, Elliott D. SoRelle1,3,5,

Orly Liba1,2,3,4, Adam de la Zerda1,2,3,4,5

Departments of Structural Biology1 and Electrical

Engineering2, Molecular Imaging Program at

Stanford (MIPS)3, Stanford Bio-X4, and

Biophysics Program5, Stanford University

95 Matrix Malleability Regulates Cancer Cell Migration Through Confining

Microenvironments

Katrina M. Wisdom1, Kolade Adebowale2, Rajiv

Desai3,5, Louis Hodgson4, Ovijit Chaudhuri1

Departments of Mechanical Engineering1 and

Chemical Engineering2, Stanford University;

Departments of Engineering5 and Applied

Sciences3, Harvard University; Gruss-Lipper

Biophotonics Center4, Albert Einstein College of

Medicine

96 Faster and More Accurate Cerebral Blood Flow (CBF) Estimation from

Arterial Spin Labeling (ASL) MRI Using Deep Learning

Enhao Gong1, Jia Guo2, John Pauly1, Greg

Zaharchuk2

Departments of Electrical Engineering1 and

Radiology2, Stanford University

97 High Intensity Focused Ultrasound Modeling for Transcranial Treatments

Steve Leung1, Taylor Webb2, Kim Butts Pauly3

Departments of Bioengineering1, Electrical

Engineering2, and Radiology3, Stanford

University

98 Convexity Properties of Artificial Neural Networks

Blaine Rister1, Daniel Rubin2,3,4

Departments of Electrical Engineering1,

Radiology2, Medicine (Division of Bioinformatics

Research3), and Biomedical Data Science4,

Stanford University

99 CD81: A Novel Lymphoma Therapeutic Target

Felipe Vences-Catalán1, Chiung-Chi Kuo1,

Ranjani Rajapaksa1, Caroline Duault1, Ron Levy1,

Shoshana Levy1

Department of Medicine (Division of Oncology1),

Stanford University

100 Integrated Molecular and Clinical Analysis for Understanding Human

Disease Relationships

Winston A. Haynes1,2, Rohit Vashisht1, Francesco

Vallania2, Charles Liu2, Gregory L. Gaskin1,

Erika Bongen2, Shane Lofgren1,2, Timothy E.

Sweeney1,2, Paul J. Utz3, Nigam H. Shah1*,

Purvesh Khatri1,2*

(*corresponding authors) Stanford Center for

Biomedical Informatics Research1 and Institute

for Immunity, Transplantation, & Infection2,

Stanford University

101 A Completely Novel Class of Intravenous Anesthetics without

Hemodynamic Sequelae: “Translating from in silico to Behavior”

Edward J. Bertaccini1,2, M. Frances Davies1,2, Yao

Li1, Yun Wu1, Eric R. Gross1, Noëlie S.J. Cayla1,

Beza A. Dagne1, M. Bruce MacIver1

Department of Anesthesiology, Perioperative &

Pain Medicine1, Stanford University; Department

of Veterans Affairs2, Palo Alto VA Health Care

System

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102 Generation of EEG Oscillations of Neocortical Brain Slices

Noëlie S.J. Cayla1, Stephen W. Evans2, Beza A.

Dagne1, M. Bruce MacIver1,2

Department of Anesthesiology, Perioperative &

Pain Medicine1 and Neurosciences Progam2,

Stanford University

103 New Anesthetic Discovery: Towards a Safer ‘Etomidate’

Lawrence L. Fu1, Noëlie S. Cayla1, Beza A.

Dagne1, Timothy H. Li1, M. Frances Davies1,2,

Edward J. Bertaccini1,2, M. Bruce MacIver1

Department of Anesthesiology, Perioperative &

Pain Medicine1, Stanford University; Department

of Anesthesia2, VA Palo Alto Health Care System

104 Teasing Apart the Desired Effects of Anesthetics from Unwanted Side

Effects at GABAA Receptors

Noëlie S. Cayla1, Beza A. Dagne1, M. Frances

Davies1, M. Bruce MacIver1, Edward J.

Bertaccini1,2

Department of Anesthesiology, Perioperative &

Pain Medicine1, Stanford University; Department

of Anesthesia2, Palo Alto VA Health Care System

105 Epithelial Separation in an Oral Mouse Wound Model: A Theory for

Post-Tonsillectomy Secondary Hemorrhage

Daniel M. Beswick1, Chloe Santa Maria1, Noel F.

Ayoub1, Robson Capasso1, Peter Luke Santa

Maria1,2,3

Department of Otolaryngology, Head & Neck

Surgery1, Stanford University; Ear Sciences

Centre2, The University of Western Australia; Ear

Science Institute Australia3, Australia

106 Reduced BMPR2 Signaling Impairs Right Ventricular Heart Function

and Exaggerates Cardiac Fibrosis upon Chronic Pressure Overload

Mario Boehm1, Xuefei Tian1, Mingming Zhao2,

Svenja Dannewitz1, Kazuya Kuramoto1, Jerry

Kuang1, Sushma Reddy2, Daniel Bernstein2, Euan

Ashley3, Edda Spiekerkoetter1

Departments of Medicine (Divisions of

Pulmonary & Critical Care Medicine1 and

Cardiovascular Medicine3) and Pediatrics

(Division of Pediatric Cardiology2), Stanford

University

107 Enzastaurin Reverses Vascular Remodeling in Experimental Pulmonary

Hypertension by Targeting the Novel BMPR2 Modifier FHIT

Svenja Dannewitz Prosseda1, Kazuya Kuramoto1,

Xuefei Tian1, Kazuya Miyagawa1, Mario Boehm1,

Fan Zhang2, David Solow-Cordero3, Joshua

Saldivar3, Eric Austin4, James E. Loyd4, Kay

Huebner5, Purvesh Khatri6, Ross J. Metzger2,

Edda Spiekerkoetter1,2,7

Departments of Medicine (Division of Pulmonary

& Critical Care1), Chemical & Systems Biology3,

and Bioinformatics6, Vera M. Wall Center for

Pulmonary Vascular Disease2, and Cardiovascular

Research Institute7, Stanford University;

Departments of Pediatrics and Medicine4,

Vanderbilt University; Department of Virology5,

Ohio State University

108 Cryo-EM Structure of Histone H3K4 Methyltransferase COMPASS

Qianhui Qu1, Yohhei Takahashi2, Jean-François

Couture3, Ali Shilatifard2, Georgios Skiniotis1

Department of Molecular & Cellular Physiology1,

Stanford University; Department of Biochemistry

& Molecular Genetics2, Northwestern University;

Structural Biology & Epigenetics3, University of

Ottawa

109 Manipulation of Nuclear Architecture through CRISPR Mediated

Chromosomal Looping

Stefanie L. Morgan1,2, Natasha C. Mariano1,2,

Abel Bermudez3,4, Nicole L. Arruda5, Fangting

Wu6, Yunhai Luo1,2, Gautam Shankar1,2, Chiao-

Chain Huang6, Sharon J. Pitteri3,4, Kevin C.

Wang1,2,7

Departments of Dermatology (Program in

Epithelial Biology1) and Radiology4, Program in

Cancer Biology2, and Canary Center for Cancer

Early Detection3, Stanford University;

Department of Biology5, Bridgewater State

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University, MA; System Biosciences6, Palo Alto;

VA Palo Alto Healthcare System7

110 Contrastive Principal Component Analysis

Abubakar Abid1, Vivek Bagaria1, Martin Zhang1,

James Zou2

Departments of Electrical Engineering1 and

Biomedical Data Science2, Stanford University

111 Mechanosensory Inputs in Adaptive Intestinal Growth

Anna A. Kim1,2, Shruthi Balachandra2, Lucy E.

O’Brien2*, Beth L. Pruitt1,2,3*

(*corresponding authors) Departments of

Mechanical Engineering1, Molecular & Cellular

Physiology2, and Bioengineering3, Stanford

University

112 Fine Mapping Genome-Wide Association in Narcolepsy Defines Novel

Disease Mechanisms

Hanna M. Ollila1, Ryan Hillary1, Ling Lin1,

Joachim Hallmayer2, Fang Han3, Jimmie Ye4,

Emmanuel Mignot1*

(*corresponding author) Stanford University

Center for Sleep Sciences1 and Department of

Psychiatry & Behavioral Sciences2, Stanford

University; Department of Surgery3, Peking

University People’s Hospital, Beijing, China;

Department of Epidemiology & Biostatistics4,

Institute of Human Genetics, University of

California, San Francisco

113 Cell Type-Specific Chromatin Signatures Underline Regulatory DNA

Elements in Human Induced Pluripotent Stem Cells and Cardiac Cells

Ming-Tao Zhao1,2,3*, Ning-Yi Shao1,2,3*, Shijun

Hu1,2,3*, Ning Ma1,2,3, Rajini Srinivasan4,

Fereshteh Jahanbani5, Jaecheol Lee1,2,3, Michael

P. Snyder5†, Joseph C. Wu1,2,3†

(*co-first authors; †corresponding authors)

Stanford Cardiovascular Institute1, Departments

of Medicine (Division of Cardiology2), Chemical

& Systems Biology4, and Genetics5, and Institute

for Stem Cell Biology & Regenerative Medicine3,

Stanford University

114 Induced Pluripotent Stem Cell Derived Cardiomyocytes on Engineered

Platforms Allows for Assessment of Cardiomyocyte Function

Alison Schroer1,2,3, Gaspard Pardon1, Robin

Wilson1, Aleksandra Denisin1, Erica Castillo1,

Kristina Kooiker2,3,4, Arjun Adhikari2,3, Yen Sin

Ang6, James Spudich2,3, Daniel Bernstein2,4,

Bruce Conklin6, Deepak Srivastava6, Sean Wu2,5,

Alexandre Ribeiro1,2,6, Beth Pruitt1,2

Departments of Mechanical Engineering1,

Biochemisty3, Pediatric Cardiology4, and

Cardiovascular Medicine5 and Cardiovascular

Institute2, Stanford University; Gladstone Institute

of Cardiovascular Disease6, San Francisco

115 Novel CMKLR1 Inhibitors and Structure Activity Relationship Studies

for Application in Demyelinating Disease

Vineet Kumar1, Melissa LaJevic2, Sanjay

Malhotra1, Brian A. Zabel2

Department of Radiation Oncology1, Stanford

University; Palo Alto Veterans Institute for

Research2

116 Small Molecules Facilitating DNA Repair in Breast Cancer Cells

Kedar Hastak1, Vineet Kumar2, Mallesh

Pandrala2, Makelle Gardiner1, Sanjay V.

Malhotra2,3, James M. Ford1

Departments of Medicine (Division of Oncology1)

and Radiation Oncology2 and Molecular Imaging

Program at Stanford (MIPS)3, Stanford University

117 Dual Functions of Flagellum in Motility and Cell Shape Modulation in

Trypanosoma brucei

Stella Y. Sun1,2, Jason T. Kaelber4, Muyuan

Chen4, Xiaoduo Dong3, Jian Shi3, Matthew

Dougherty4, Yasaman Nematbakhsh5, Lim Chwee

Teck5, Steven J. Ludtke4, Michael F. Schmid1,2,

Cynthia Y. He3, Wah Chiu1,2

SLAC National Accelerator Laboratory1 and

Department of Bioengineering2, Stanford

University; Department of Biological Sciences3,

National University of Singapore; National Center

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for Macromolecular Imaging4, Baylor College of

Medicine; Department of Mechanical

Engineering5, National University of Singapore

118 The 3.5 Å Cryo-EM Structure of Nanodisc Reconstituted Yeast Vacuolar

ATPase Vo Proton Channel

Soung-Hun Roh1, Nicholas J. Stam2, Corey F.

Hryc3, Sergio Couoh-Cardel2, Grigore Pintilie3,

Stephan Wilkens2, Wah Chiu1

Department of Bioengineering1, Stanford

University; Department of Biochemistry &

Molecular Biology2, SUNY Upstate Medical

University; National Center for Macromolecular

Imaging3, Baylor College of Medicine

119 7 Angstrom Cryo-EM Structure of Tbox Riboswitch and tRNA Complex

Zhaoming Su1, Shuang Li2, Jinwei Zhang2, Wah

Chiu1

Department of Bioengineering1, Stanford

University; Laboratory of Molecular Biology2,

NIDDK, NIH

120 Cryo-EM of 30 kDa HIV-1 RNA Dimer Initiation Site

Kaiming Zhang1, Sarah C. Keane2,3, Zhaoming

Su1, Rossitza N. Irobalieva6,7, Jan Marchant2,3,

Xiao Heng4, Michael F. Schmid1, David A. Case5,

Steven J. Ludtke6,7, Michael F. Summers2,3, Wah

Chiu1*

(*corresponding author) Department of

Bioengineering1, Stanford University; Howard

Hughes Medical Institute (HHMI)2 and

Department of Chemistry & Biochemistry3,

University of Maryland, Baltimore County

(UMBC); Department of Biochemistry4,

University of Missouri—Columbia; Department

of Chemistry & Chemical Biology5, Rutgers

University; National Center for Macromolecular

Imaging6 and Verna & Marrs McLean

Department of Biochemistry & Molecular

Biology7, Baylor College of Medicine

121 The CEP19-RABL2 GTPase Complex Binds IFT-B to Initiate

Intraflagellar Transport at the Ciliary Base

Tomoharu Kanie1,2, Peter K. Jackson1,2

Baxter Laboratory1 and Department of

Microbiology & Immunology2, Stanford

University

122 Rapid Bacterial Identification Based on Surface-Enhanced Raman

Scattering and Machine Learning

Chi-Sing Ho1, Neal Jean2, Amr Saleh3, Stefano

Ermon4, Niaz Banaei5, Jennifer Dionne3

Departments of Applied Physics1, Electrical

Engineering2, Materials Science & Engineering3,

Computer Science4, and Pathology5, Stanford

University

123 Evidence That the Human Innate Immune Peptide LL-37 May Be a

Binding Partner of Aβ and Inhibitor of Fibril Assembly

Ersilia De Lorenzi1, Marcella Chiari2*, Raffaella

Colombo1, Marina Cretich2, Laura Sola2, Renzo

Vanna3, Paola Gagni2, Federica Bisceglia1, Carlo

Morasso3, Jennifer S. Lin5, Moonhee Lee4, Patrick

L. McGeer4, Annelise E. Barron5*

(*corresponding authors) Department of Drug

Sciences1, University of Pavia, Italy; Institute of

Chemistry of Molecular Recognition2, National

Research Council of Italy; Laboratory of

Nanomedicine and Clinical Biophotonics

(LABION)3, Fondazione Don Carlo Gnocchi

ONLUS, Italy; Kinsmen Laboratory of

Neurological Research4, University of British

Columbia, Canada; Department of

Bioengineering5, Stanford University

124 Significant ERK1/2 Phosphorylation but No Change in Dual Specificity

Phosphatase 14 After Acute Ischemic Optic Neuropathy

Varun Kumar1, Yaping Joyce Liao1, Jeffrey L.

Goldberg1

Department of Ophthalmology1, Stanford

University

125 Bayesian Online Haplotype Inference Method for Portable DNA

Sequencers Yosuke Tanigawa1, Manuel Rivas1,2

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Biomedical Informatics Training Program1 and

Department of Biomedical Data Science2,

Stanford University

126 Single-Cell Map of Microbe-Immune Transcriptome

Ryan Kellogg1,2, Feiqiao Yu1, Stephen Quake1,

Mike Snyder2

Departments of Bioengineering1 and Genetics2,

Stanford University

127 Designing Novel Nani-Ores for Detection of Small Molecules

Jamin Koo1, Andres Parberg1, Jessyln Janssen2,

Possu Huang1

Department of Bioengineering1, Stanford

University; Department of Biology2, University of

Manitoba

128 Inhibition of NGLY1 Inactivates the Transcription Factor Nrf1 and

Potentiates Proteasome Inhibitor Cytotoxicity

Fred Tomlin1, Ulla Gerling-Driessen1, Carolyn

Bertozzi1

Department of Chemistry1, Stanford University

129 Quantification of Transplant-Derived Circulating Cell-Free DNA in

Absence of a Donor Genotype

Eilon Sharon1,2*, Hao Shi8, Sandhya Kharbanda3,

Winston Koh4,5,6, Lance R. Martin4,5,6, Kiran K.

Khush7, Hannah Valantine8, Jonathan K.

Pritchard1,2,4*, Iwijn De Vlaminck9*

(*corresponding authors) Departments of

Genetics1, Biology2, Bioengineering5, Applied

Physics6, and Medicine (Division of

Cardiovascular Medicine7) and Howard Hughes

Medical Institute4, Stanford University; Pediatric

Stem Cell Transplantation3, Lucile Packard

Children’s Hospital; National Institutes of

Health8, Bethesda, Maryland; Meinig School of

Biomedical Engineering9, Cornell University

130 Social Control of Hypothalamus-Mediated Male Aggression

Taehong Yang1, Cindy F. Yang5, M. Delara

Chizari6, Niru Maheswaranathan2, Kenneth J.

Burke, Jr.5, Maxim Borius6, Sayaka Inoue1,

Michael C. Chiang6, Kevin J. Bender7, Surya

Ganguli3,4, Nirao M. Shah1,4

Departments of Psychiatry & Behavioral

Sciences1, Applied Physics3, and Neurobiology4

and Neurosciences Program2, Stanford

University; Program in Neuroscience5 and

Departments of Anatomy6 and Neurology7,

University of California, San Francisco

131 Harnessing Controlled Release Polymer-Nanoparticle Hydrogel to

Produce Robust Long-Term Immunity

Gillie Agmon1, Anthony C. Yu2, Caitlin L.

Maikawa1, Emily C. Gale3, Eric A. Appel2

Departments of Bioengineering1, Materials

Science & Engineering2, and Biochemistry3,

Stanford University

132 Role of Transcription Factor Er81/ETV1 in the Enteric Nervous System

Josphine L. Belluardo1*, Subhamoy Das2*,

Richard J. DiCasoli1, Michael D. Gershon3, Julia

A. Kaltschmidt2

(*co-first authors) Developmental Biology

Program1, Sloan Kettering Institute, Memorial

Sloan Kettering Cancer Center; Department of

Neurosurgery2, Stanford University; Department

of Pathology & Cell Biology3, Columbia

University

133 Supramolecular CB[7] Designer Excipient for Improved Insulin

Formulations

Caitlin L. Maikawa1, Gillie Agmon1, Emily C.

Gale2, Bruce A. Buckingham3, David M. Maahs3,

Eric A. Appel4

Departments of Bioengineering1, Biochemistry2,

Pediatrics3, and Materials Science &

Engineering4, Stanford University

134

A Novel Bed-Mounted Projection System is Superior to Pharmacological

Agent Midazolam and Does Not Increase Pre-Induction Time When

Managing Pediatric Preoperative Anxiety: A Retrospective Study

Jeremy H. Tsui1, Thomas J. Caruso1, Samuel

Rodriguez1

Department of Anesthesiology, Perioperative, &

Pain Medicine1, Stanford University

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135 Immersive Virtual Reality (VR) Improves Compliance During a Minor

Procedure

Jeremy H. Tsui1, Justin C. Yuan1, Michael

Khoury1, Vincent Sferra1, Meagan Wu1, Kevin

Chen1, Gavin Traber1, Vaibhav Murali1, Jessica

Maya Hernandez1, Alexandria Joseph1, Samuel

Rodriguez1, Thomas J. Caruso1

Department of Anesthesiology, Perioperative, &

Pain Medicine1, Stanford University

136

Provider Controlled Virtual Reality Experience Adjusts Cognitive Load

to Reduce Fear and Perceptual Pain During Intravenous Access in

Pediatric Patients

Samuel Rodriguez1, Justin C. Yuan1, Jeremy H.

Tsui1, Gavin Traber1, Vincent Sferra1, Meagan

Wu1, Jessica Maya Hernandez1, Thomas J.

Caruso1

Department of Anesthesiology, Perioperative, &

Pain Medicine1, Stanford University

137 Building Systems to Support and Sustain Virtual Reality in the Inpatient

Setting

Alexandria Joseph1, Jeremy H. Tsui1, Kevin

Chen1, Gavin Traber1, Meagan Wu1, Samuel

Rodriguez1, Thomas J. Caruso1

Department of Anesthesiology, Perioperative, &

Pain Medicine1, Stanford University

138 Ethical Implications for Virtual Reality Induced False Memory

Formation in Pediatric Patients

Justin C. Yuan1,2, Jeremy H. Tsui2, Kevin Chen2,

Thomas J. Caruso2, Samuel Rodriguez2, Alyssa

M. Burgart2

William Beaumont School of Medicine1, Oakland

University; Department of Anesthesiology,

Perioperative, & Pain Medicine2, Stanford

University

139 Technical Solutions for Implementation of Virtual Reality Headsets in

the Hospital Setting

Ben Chuter1, Justin C. Yuan1,2, Andrew

Terajewicz1, Michael Khoury1, Vincent Sferra1,

Samuel Rodriguez1

Department of Anesthesiology, Perioperative, &

Pain Medicine1, Stanford University; William

Beaumont School of Medicine2, Oakland

University

140 Reading and Ocular Motor Abnormalities in Cerebellar Ataxia

Angela Oh1, Joyce Liao1

Department of Ophthalmology1, Stanford

University

141

The Landscape of Genomic and Clonal Characterization of Immunogenic

Neoepitopes Across >10,000 Samples from 32 Cancers in the Cancer

Genome Atlas (TCGA)

HoJoon Lee1, Susan M. Grimes2, Stephanie

Greer2, Anurag Sethi3, Jae-Ho Cheong4, Hanlee P.

Ji1,2

Department of Medicine (Division of Oncology1)

and Stanford Genome Technology Center2,

Stanford University; Seven Bridges Genomics,

Inc.3, Cambridge, MA; Department of Surgery4,

Yonsei University, Seoul, Korea

142 Predicting the Molecular Crosstalk Between Transplanted Cells and the

Ischemic Brain Using Transcriptome Analysis

Ricardo L. Azevedo-Pereira1,2, Nathan C.

Manley1,2, Jennifer Vu1,2, Mårten C. Winge3, Jack

Berry1,2, Guohua Sun1,2, Tonya Bliss1,2, Gary K.

Steinberg1,2

Departments of Neurosurgery1 and Dermatology3

and Stanford Stroke Center2, Stanford University

143 Trop2 as a Driver of Aggressive Prostate Cancer

En-Chi Hsu1,2, Meghan A. Rice1,2, Rosalie

Nolley3, Jiaoti Huang4, Abel Bermudez1,2, Sharon

Pitteri1,2, Donna M. Peehl3, James D. Brooks3,

Tanya Stoyanova1,2

Departments of Radiology1 and Urology3 and

Canary Center for Cancer Early Detection2,

Stanford University; Department of Pathology4,

Duke University

144 Utilizing Magnetic Levitation as Inexpensive, Platelet Based Early

Cancer Diagnostic Modality

Loza Tadesse1,3, Utkan Demirci2,3

Departments of Bioengineering1 and Radiology2

and Canary Center for Cancer Early Detection3,

Stanford University

145 Unique Serum Metabolomic Profiles in Preeclampsia: Implications for

Pathophysiology

Zhen Li1, Xin Liu1, Shiying Hao2,3, Jin You1,

Jaehong Kim1, Karl Sylvester1, Doff

McElhinney2,3, Harvey Cohen4, Bruce Ling1,3

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Departments of Surgery1, Cardiothoracic

Surgery2, and Pediatrics4, Stanford University;

Clinical & Translational Research Program3,

Betty Irene Moore Children’s Heart Center,

Lucile Packard Children’s Hospital

146 Molecular Regulation of Neutrophil Cell Surface Sialyation and the

Siglec-9 Mediated Neutrophil Death

Yue Wang1, Zhen Li1, Guang Hu1, Shiying Hao2,5,

Xiaohong Deng1, Min Huang6, Miao Ren1,

Xiyuan Jiang1, John T. Kanegaye7,8, Kee-Soo Ha9,

JungHwa Lee9, Xiaofeng Li10, Xuejun Jiang11,

Yunxian Yu4, Adriana H. Tremoulet7,8, Jane C.

Burns7,8, John C. Whitin3, Andrew Y. Shin3, Karl

G. Sylvester1, Doff B. McElhinney3,5, Harvey J.

Cohen3, Xuefeng B. Ling1,4,5, the Pediatric

Emergency Medicine Kawasaki Disease Research

Group8

Departments of Surgery1, Cardiothoracic

Surgery2, and Pediatrics3, Stanford University;

School of Public Health4, School of Medicine,

Zhejiang University, China; Clinical &

Translational Research Program5, Betty Irene

Moore Children’s Heart Center, Lucile Packard

Children’s Hospital; The Speciality of

Cardiovascular Disease6, Shanghai Children’s

Hospital, China; Department of Pediatrics7,

University of California, San Diego; Rady

Children’s Hospital8, San Diego; Department of

Pediatrics9, Guro Hospital, Korea University

Medical Center; Department of Heart Center10,

Beijing Children’s Hospital, China; Cell Biology

Program11, Memorial Sloan-Kettering Cancer

Center

147

Comparison of 18F-FDG PET/MR, Whole Body DW MR and Clinical

Standard Imaging Tests for Treatment Monitoring of Solid Cancers in

Children and Young Adults

Ramitha Nyalakonda1,2, Ashok J. Theruvath1,2,

Anne M. Muehe1,2, Sandra Luna-Fineman3, Arun

A. Rangaswami2, Sheri L. Spunt3, Heike E.

Daldrup-Link1,2

Department of Radiology1 and Molecular Imaging

Program at Stanford (MIPS)2, Stanford

University; Department of Pediatrics (Pediatric

Oncology3), Lucile Packard Children’s Hospital

148 Hypoxia Driven Epigenetic Modifications Regulated Retinoic Acid-

Induced Differentiation in Human Neuroblastoma Cells

Yang Li1, Yiren Zhou1, John M. Maris2, Amato J.

Giaccia1, Jiangbin Ye1

Department of Radiation Oncology1, Stanford

University; Department of Pediatric Hematology

& Oncology2, Children’s Hospital of Philadelphia

149 Targeting Serine and One-Carbon Metabolism in Metastatic Breast

Cancer

Albert M. Li1,2, Gregory S. Ducker6,7, Yang Li1,

Jose A. Seoane3, Yiren Zhou1, Ling Liu6,7, Sakari

Vanharanta5, Erinn B. Rankin1,2, Joan Massagué5,

Christina Curtis2,3,4, Joshua D. Rabinowitz6,7,

Craig B. Thompson5, Jiangbin Ye1,2

Departments of Radiation Oncology1 and

Medicine3, Cancer Biology Program2, and

Stanford Cancer Institute4, Stanford University;

Cancer Biology & Genetics Program5, Memorial

Sloan Kettering Cancer Center; Lewis-Sigler

Institute for Integrative Genomics6 and

Department of Chemistry7, Princeton University

150 Toward Decoding Temporal Anticipation from Single Trial EEG Data

Emily Graber1,2, Takako Fujioka1,2,3

Center for Computer Research in Music &

Acoustics1, Department of Music2, and Stanford

Neurosciences Institute3, Stanford University

151 A Systematic Study of Swelling-Induced Instabilities of Hydrogels

Berkin Dortdivanlioglu1, Christian Linder1

Department of Civil & Environmental

Engineering1, Stanford University

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152 Radiolabeling Exosomes using PET Reporter Genes and Probes

Elise Robinson1,2, Gayatri Gowrishankar2, Travis

Shaffer2, Cayo Gonzalez2,3, Vigneshwaran

Mani2,4, Utkan Demirci2,4, Sanjiv Sam

Gambhir1,2,4

Departments of Bioengineering1 and Radiology2

and Canary Center for Cancer Early Detection4,

Stanford University; Department of Biochemistry

& Molecular Biophysics3, Columbia University

153 Electroactive Polymer-Based Haptic Feedback in Teleoperated Needle

Membrane Puncture

Katerina C. Gregoriou1, Amy Kyungwon Han1,

Jung Hwa Bae1, Bruce L. Daniel2, Mark

Cutkosky1

Departments of Mechanical Engineering1 and

Radiology2, Stanford University

154 Department of Comparative Medicine’s Pathology and Diagnostic

Services

Kerriann Casey1, Roberta Moorhead1, Jose

Vilches-Moure1

Department of Comparative Medicine1, Stanford

University

155 Instrumentation for Combining Electrical Brain Stimulation with EEG

Recording

Vladimir Vildavski1, Angelo Dragone2, Jeff

Olsen2, Chris Kenney2, Ryan Herbst2, Stephen

Boyd3, Nolan Williams4, Marty Breidenbach2,

Anthony Norcia1

Departments of Psychology1, Electrical

Engineering3, and Psychiatry & Behavioral

Sciences4 and SLAC National Accelerator

Laboratory2, Stanford University

156 Adhesion Prevention Using Polymer Nanoparticle (PNP) Hydrogels

Lyndsay Stapleton1, Amanda Steele1, Akshara

Thakore2, Anthony Yu3, Joseph Woo2, Eric

Appel3

Departments of Bioengineering1, Cardiothoracic

Surgery2, and Materials Science & Engineering3,

Stanford University

157 Measuring Microscopic Diffusion Anisotropy in Multiple Sclerosis

Patients with Double Diffusion Encoding MRI

Grant Yang1,2, Qiyuan Tian1,2, Christoph Leuze2,

Max Wintermark2, Jennifer McNab2 Departments of Electrical Engineering1 and

Radiology2, Stanford University

158 Predicting Prostate Cancer Recurrence Using Structured Pre-Operative

EMR Data

Martin Seneviratne1, James Brooks2, Michelle

Ferrari2, Nigam Shah1, Tina Hernandez-Boussard1

Departments of Medicine (Biomedical

Informatics Research1) and Urology2, Stanford

University

159 Miniaturized Optical BioSensor for Point-of-Care Total Protein

Measurement

Fariah Mahzabeen1, Ophir Vermesh2, Sanjiv S.

Gambhir2,3, James S. Harris1

Departments of Electrical Engineering1 and

Radiology2 and Canary Center for Cancer Early

Detection3, Stanford University

160 Correlation of Stented Renal Geometry and Respiratory-Induced

Deformation with Respect to Stented Length in Complex EVAR Patients

John Kim1,2, Ga-Young Suh1, Jason T. Lee1,

Christopher P. Cheng1

Department of Vascular Surgery1, Stanford

University; Department of Biology2, University of

Chicago

161 Modeling Brownian Spheroidal Nanoparticles in Near-Wall Vascular

Flows

Tiras Y. Lin1, Preyas N. Shah1, Bryan R. Smith2,

Eric S.G. Shaqfeh1,3

Departments of Mechanical Engineering1,

Radiology2, and Chemical Engineering3, Stanford

University

162 Injectable Self-Organizing Microtissues for Rapid Host Vascularization

of Ischemic Tissues

Ninna S. Rossen1,2, Rafael zur Nieden2, Kahmun

Lo2, Danielle R. Bajakian3, Brian M. Gillette2,

Samuel K. Sia2

Department of Radiation Oncology1, Stanford

University; Department of Biomedical

Engineering2 and NewYork–Presbyterian

Hospital3, Columbia University

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163 Upconverting Nanoparticles as Optical Sensors of Nano- to Micro-

Newton Forces

Alice Lay1, Derek Wang2, Michael Wisser2,

Randy Mehlenbacher2, Yu Lin3, Wendy Mao4,

Miriam Goodman5, Jennifer Dionne2

Departments of Applied Physics1, Materials

Science & Engineering2, Geological Sciences4,

and Molecular & Cellular Physiology5 and SLAC

Institute for Materials & Energy Sciences3,

Stanford University

164 Stem Cell Transplantation as Treatment for Acute Ischemic Optic

Neuropathy

Louise A. Mesentier-Louro1, Mohammad Ali

Shariati1, Kyle Marra2, Varun Kumar1, Martin

Friedlander2, Yaping Joyce Liao1

Department of Ophthalmology1, Stanford

University; Department of Cell & Molecular

Biology2, The Scripps Research Institute

165 Simultaneous Brain and Spinal Cord fMRI Using Slice-Based Dynamic

Shimming

Christine Law1, Haisam Islam2, Sean Mackey1,

Gary Glover3

Departments of Anesthesia1, Bioengineering2, and

Radiology3, Stanford University

166 Discovering Bacterial Lipids and Lipid Synthesis Enzymes to Clarify

Interpretation of the Molecular Fossil Record

Amy B. Banta1, Jeremy H. Wei1, Alysha Lee1,

Jose L. Giner2, Paula V. Welander1

Department of Earth System Science1, Stanford

University; Department of Chemistry2, State

University of New York (SUNY) College of

Environmental Science & Forestry

167 Deep Convolutional Neural Networks for Accelerated Dynamic Magnetic

Resonance Imaging

Christopher M. Sandino1, Neerav Dixit1, Joseph

Y. Cheng2, Shreyas S. Vasanawala2

Departments of Electrical Engineering1 and

Radiology2, Stanford University

168 A New SMS Sequence for fMRI: POMP

Patricia Lan1, Gary Glover2

Departments of Bioengineering1 and Radiology2,

Stanford University

169 Functional and Histological Analysis of a Mouse Model of Oculocerebral

Renal Syndrome of Lowe

Jorge A. Alvarado1, Na Luo2, Emilie Song2,

Judith Quigley2, Yang Sun1

Department of Ophthalmology1, Stanford

University; Eugene & Marilyn Glick Eye

Institute2, Indiana University School of Medicine

170

Long Term Effect of High Frequency Deep Brain Stimulation on

Subthalamic Beta Band Oscillations and Motor Function in Parkinson’s

Disease

Amaris Martinez1, Anca Velisar1, Ross

Anderson1, Furqan Afzal1, Megan Trager1, Helen

Bronte-Stewart1,2

Departments of Neurology & Neurological

Sciences1 and Neurosurgery2, Stanford University

171 Intravascular Shear Wave Elastography

Arsenii Telichko1, Carl Herickhoff1, Dongwoon

Hyun1, Jeremy Dahl1

Department of Radiology1, Stanford University

172

Moving from Inter-Regional to Inter-Personal Network Science to

Examine Neural Correlates of Effective Team Collaboration: A

Simultaneous 3-Person fMRI Study

Manish Saggar1, Amber Howell1, Malte Jung2,

Gary Glover3, Allan Reiss1,3

Departments of Psychiatry & Behavioral

Sciences1 and Radiology3, Stanford University;

Department of Information Science2, Cornell

University

173 Using Algebraic Topology to Examine Brain’s Dynamical Organization

During Ongoing Cognition

Manish Saggar1, Olaf Sporns2, Gunnar Carlsson3,

Gary Glover4, Allan Reiss1,4

Departments of Psychiatry & Behavioral

Sciences1, Mathematics3, and Radiology4,

Stanford University; Department of Cognitive

Science2, Indiana University

174 Cationic Amphiphilic Compounds Restrict Intracellular Mycobacterium

tuberculosis

Douglas Fox1, Michael Schump2, Lee Riley2

Carolyn Bertozzi1,3

Department of Chemistry1 and Howard Hughes

Medical Institute3, Stanford University; Graduate

Group in Infectious Diseases & Immunity2,

School of Public Health, University of California,

Berkeley

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175 Building a Generic, Configurable, and User-Friendly Real-Time

Computation Engine

Sabar Dasgupta1,2, Pavan Mehrotra1,2, Samantha

Robertson2,3, Paul Nuyujukian1,2,4,5,6,7

Departments of Electrical Engineering1,

Bioengineering2, and Neurosurgery4,

Mathematical & Computational Science

Program3, Neurosciences Program5, Stanford

Neurosciences Institute6, and Stanford Bio-X7,

Stanford University

176 Deploying Realtime Linux with Python for Applications in Systems

Neuroscience

Samantha Robertson1,2, Sabar Dasgupta3,2, Paul

Nuyujukian2,3,4,5,6,7

Mathematical & Computational Science

Program1, Departments of Bioengineering2,

Electrical Engineering3, and Neurosurgery4,

Neurosciences Program5, Stanford Neurosciences

Institute6, and Stanford Bio-X7, Stanford

University

177 The Mechanism of Rb Ohosphorylation by Cyclin D-Cdk4/6

Benjamin R. Topacio1,2, Mardo Kõivomägi1,

Evgeny Zatulovskiy1, Jan M. Skotheim1

Department of Biology1 and Cancer Biology

Program2, Stanford University

178 Pressure Calibration for Transcranial Ultrasound Using Simulation

Methods and MR-ARFI

Pooja Gaur1, Ningrui Li2, Kim Butts Pauly1

Departments of Radiology1 and Electrical

Engineering2, Stanford University

179 Arsenic and the Microbiome: Towards Microbiome-Centric Public

Health Interventions

Stephanie Bachas-Daunert1, Sooyeol Kim1, Juan

Lezama Pacheco2, Craig S. Criddle1, David A.

Relman3,4

Departments of Civil & Environmental

Engineering1, Earth System Science2, Medicine3,

and Microbiology & Immunology4, Stanford

University

180 Loss of Cilia in Ocular Melanoma: Implications for Diagnosis

Emilie Song1, Elaine Chan1, Yang Sun1

Department of Ophthalmology1, Stanford

University

181 Direct Selection of Fluorescence-Enhancing RNA Aptamers

Michael Gotrik1,2,3, Gurpreet Sekhon2,3, Tom

Soh2,3

Materials Department1, University of California,

Santa Barbara; Departments of Radiology2 and

Electrical Engineering3, Stanford University

182 Heightened Threat Perception in Adolescents with Chronic Pain

Anna Park1, Molly Fischer1, Vaibhav Murali1,

Corey Kronman2,3, Farah Mahmud2,3, Maya

Hernandez1, Laura Simons1

Department of Anesthesiology, Perioperative, &

Pain Medicine1, Stanford University; Department

of Anesthesiology, Perioperative, & Pain

Medicine2, Boston Children’s Hospital; P.A.I.N.

(Pain & Anelgesia Imagining Neuroscience)

Group3, Boston Children’s Hospital and Center

for Pain in the Brain, Harvard Medical School

183 Alterations in Memories for Fearful Experiences Among Youth with

Chronic Pain

Molly Fischer1, Anna Park1, Maya Hernandez1,

Corey Kronman2,3, Farah Mahmud2,3, Laura

Simons1

Department of Anesthesiology, Perioperative, &

Pain Medicine1, Stanford University; Department

of Anesthesiology, Perioperative, & Pain

Medicine2, Boston Children’s Hospital; P.A.I.N.

(Pain & Anelgesia Imagining Neuroscience)

Group3, Boston Children’s Hospital and Center

for Pain in the Brain, Harvard Medical School

184 Probing the 3D Structure of Chromatin

Mirae Parker2, Leslie Mateo1, Nasa Sinnott-

Armstrong3, Alistair Boettiger1

Departments of Developmental Biology1,

Physics2, and Genetics3, Stanford University

185 Mapping Cardiac Arrhythmic Activities in Rabbit with High

Spatiotemporal Resolution Using a Novel Elastic Polymeric Device

Xinyuan Zhang1, Joy Aparicio Valenzuela1, Jia

Liu2, Yuxin Liu2, Meghedi Babakhanian3,

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Mahmood Al Husseini4, Sanjiv Narayan4, Paul

Wang3, Zhenan Bao2, Anson Lee1

Departments of Cardiothoracic Surgery1,

Chemical Engineering2, Medicine3, and

Cardiovascular Medicine4, Stanford University

186 Single Cell Studies of Competence and Progression in Primary

Mammalian Cells

Carolyn Kravitz1, Clayton Schwarz1, Jan

Skotheim1

Department of Biology1, Stanford University

187 A Genetically Engineered Mouse Model of Fibrolamellarhepatocellular

Carcinoma

Vicky Le1,2, Garry Coles1,2, Lei Xu1,2, Thuyen

Nguyen1,2, Julien Sage1,2

Departments of Pediatrics1 and Genetics2,

Stanford University

188 The Role of OCRL in Cell Cycle Progression: Implications for

Oculocerebrorenal Syndrome of Lowe

Biao Wang1, Cathleen Wallmuth2, Na Luo2,

Xinyao Hu2, Clark Wells3, Yang Sun1

Department of Ophthalmology1, Stanford

University; Departments of Ophthalmology2 and

Biochemistry & Molecular Biology3, Indiana

University

189 Personalized Molecular Detection of Cancer Mutations

Christina Wood-Bouwens1, Billy Lau2, Bob St.

Onge2, HoJoon Lee2, Hanlee P. Ji1,2

Department of Medicine (Division of Oncology1)

and Stanford Genome Technology Center2,

Stanford University

190 Harmony and Rhythm Anticipation is Determined by the Architecture of

a Recurrent Neural Network

Irán Román1,2, Takako Fujioka1,2

Department of Music1 and Stanford

Neurosciences Institute2, Stanford University

191 Electric Field Sensitive Upconverting Nanoparticles for in vivo Action

Potential Imaging

Randy D. Mehlenbacher1, Chris Siefe1, Rea

Kolbl2, Alice Lay2, Jennifer A. Dionne1

Departments of Materials Science & Engineering1

and Applied Physics2, Stanford University

192 Combined Approach Using Bioengineering and Partial Reprogramming

of Aged Stem Cells to Treat Volumetric Muscle Loss

Marco Quarta1,2,3, Patrick Paine1,2,3, Alex

Colville1,2,3, Linda Doan1,2,3, Tapash Sarkar5,

Vittorio Sebastiano4,5, Thomas Rando1,2,3

Departments of Neurology & Neurological

Sciences1 and Obstetrics & Gynecology4, Paul F.

Glenn Laboratories for the Biology of Aging2, and

Institute for Stem Cell Biology & Regenerative

Medicine5, Stanford University; Center for Tissue

Regeneration, Restoration & Repair3, Veterans

Affairs Hospital Palo Alto

193 Widespread Differential Expression of Coding Region and 3’UTR

Sequences in Neurons and Other Tissues

Ze Yang1, Thomas Kenney1, Shaoyi Ji1, Arif

Kocabas1, Sarayna Kumar1, Mary Hynes1

Department of Biology1, Stanford University