“State of the Art Treatment” in Deformity

Adolescent Idiopathic Scoliosis

Mr Evan DaviesUniversity Hospital Southampton

Robert Jackson 1971-1995

• 1975 British Scoliosis Group

• Harrington Rod

• Spinal Cord Monitoring

• Boston Brace

Nick Boeree 1958-2012

• Appointed 1995

Screw Design

AIS

• Little High level evidence

• RCTs challenging to perform

• Low numbers of intervention

Genetics

Druk mutant Zebrafish

• Mst1rb overexpressed in pineal gland

Associations • Anterior spinal

overgrowth

• Relative shorter spinal cord length

• Tall Stature

• Low BMI

• Low bone mass

Aetiology Summary

• No single cause

• Multifactorial

• Primary genetic cause but related to fully erect posture

Treatment

Bracing

EBSJ V2(2) 2011

Blood

Excellence in Spine