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TRANSCRIPT
Supporting information for
New Tetrazoloquinolinyl Methoxy Phenyl 4-Thiazolidinones: Synthesis and
Antihyperglycemic Evaluation
Amarsinh R. Deshmukh1, Manisha R. Bhosle1, Lalit D. Khillare1, Sambhaji T. Dhumal1, Akansha
Mishra2, Arvind K. Srivastava2, Ramrao A. Mane1*
1Department of Chemistry, Dr. Babasaheb Ambedkar Marathwada University, Aurangabad (MS)
431004, India2Biochemistry Division, CSIR-Central Drug Research Institute, Lucknow-226031, India
*Corresponding author E-mail: [email protected]
This includes spectral characterization data of the intermediates and title compounds
Tetrazolo[1,5-a]quinolin-4-ylmethyl methanesulfonate (4)1H NMR
1
NN N
N
O SO
O
4-(Tetrazolo[1,5-a]quinolin-4-ylmethoxy)benzaldehyde (5)1H NMR
13C-NMR
2
HRMS
3
3-Phenyl-2-(4-(tetrazolo[1,5-a]quinolin-4-ylmethoxy)phenyl)thiazolidin-4-one (8a)1H NMR
13C-NMR
4
HRMS
3-(4-Chlorophenyl)-2-(4-(tetrazolo[1,5-a]quinolin-4-ylmethoxy)phenyl)thiazolidin-4-one (8b)1H NMR
13C-NMR
5
13C-NMR (Expansion)
HRMS
6
3-(4-Ethoxyphenyl)-2-(4-(tetrazolo[1,5-a]quinolin-4-ylmethoxy)phenyl)thiazolidin-4-one (8c)
7
1H NMR
13C-NMR
13C-NMR (Expansion)
8
HRMS
2-(4-(Tetrazolo[1,5-a]quinolin-4-ylmethoxy)phenyl)-3-(p-tolyl)thiazolidin-4-one (8d)1H NMR
9
13C-NMR
13C-NMR (Expansion)
10
HRMS
3-(4-Methoxyphenyl)-2-(4-(tetrazolo[1,5-a]quinolin-4-ylmethoxy)phenyl)thiazolidin-4-one (8g)1H NMR
11
13C-NMR
HRMS
12
13