stem cells therapy for liver cirrhosis

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Stem Cells Therapy for

Liver Cirrhosis

Email: [email protected], Mob: +91 9811011690 W: StemGenn.com

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http://StemGenn.com/

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Website : www.stemgenn.com | Email : [email protected] | Phone : +91 9910596674

Stem Cells Therapy For Liver Cirrhosis

• Liver Cirrhosis is a slowly progressing disease in which the injured and dead liver cells leads to the formation of scars tissue inside the liver.

• Apart from this the alive liver cells divide and multiply in order to replace the dead cells resulting in the formation of clusters of liver cells within the scar tissue.

• Initially liver continues to function however, with the excess deposition of scar tissue, the liver begins to fail. Due to which liver can no longer perform important function.

• As per the National Institutes of Health (NIH), Liver cirrhosis is the 12th leading cause of death in the United States. It mostly affects men as compared to women.

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Stem Cells Therapy For Liver CirrhosisCause of Liver cirrhosis Involve:

• Alcohol consumption above the level, • Obesity and Diabetes which results in fatty liver.• Chronic Viral Infection- Hepatitis B, C & D.• Blockage of bile duct due to condition known as primary biliary cirrhosis.• Repeated feeling of heart failure and fluid retention in the liver.• Reactions to drugs, parasitic infections or exposure to environmental toxins.

Certain Inherited disease also leads to cirrhosis, which include:• Hemochromatosis – Excessive iron absorption and deposition in liver and

other organs.• Wilson disease - Condition that occur due to abnormal copper deposition in

the liver.• Alpha 1 antitrypsin deficiency - Caused due to absence of a specific enzyme

in the liver and thus results in Cirrhosis.

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Stem Cells Therapy For Liver CirrhosisSymptoms of Liver Cirrhosis:Symptoms vary with the severity of the disease. In the early stages, symptoms may not be present, however as the disease worsens with excess scar deposition in the liver, symptoms include:

• Loss of appetite• Fatigue• Bruises or nose bleeds• Yellowing of whites of eyes and skin known as Jaundice.• Fluid buildup in the legs (edema) and in abdomen called ascites.• Stronger effects of normal medicines (Vitamins and herbal supplements).• Portal hypertension– Increase in blood pressure in the vein entering liver.• Kidney problems or Kidney failure.• Confusion, disorientation, personality changes• Bowel system disorder• Fever

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Diagnosis of Liver Cirrhosis

Diagnosis is not an easy task as symptoms didn’t occur in early stages however it can be diagnosed by doctors after performing:• Blood tests, which tells about the proper functioning of the

liver.• Imaging a test, this shows the abnormality in the size of the

liver, if any.• Liver biopsy, in this a small piece of liver tissue has been

examined by doctor for detecting the presence of scars.

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Stem Cells Therapy For Liver CirrhosisCurrent treatment options:

• The symptoms of the liver diseases is not visible in the early stage, due to which people didn’t came to know about this, however, Liver Cirrhosis is the chronic stage of liver failure and can be treated presently by liver transplantation by the matched donor.

• Liver transplantation can improve the condition of the patient but it has certain drawbacks as well which include infection and rejection by patient body, risk involve in surgery and shortage of donors. In fact, almost 90%-95% patient dies due to lack of donors as it is estimated that almost 30 patients are dependent on a single donor.

• To overcome these drawbacks, stem cells plays a major role. Next slide contains the description mentioning the benefit of stem cells therapy over conventional liver transplants.

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Stem Cells Therapy For Liver CirrhosisStem cells Therapy for Liver Cirrhosis• Stem cells are the novel cells which are present inside the

body.

• They have the remarkable potential of differentiating into any kind of cell and renew themselves after a certain time period or in case of damage or death of the cells.

• Due to this potential and advancements in medical science, researchers believe that stem cells therapy can be proved as a possible cure for several life threatening diseases.

• Even researchers observed effective differentiation of stem cells in hepatic lineages in case of liver.

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Stem Cells Therapy For Liver CirrhosisThe research and clinical trials are going on for finding the cure for liver failure or liver Cirrhosis however; certain therapies are available which are useful for improving the condition of the patient.The procedure of stem cells therapy involves:• Isolation of stem cells from the potent source such as bone

marrow and adipose tissue.• Processing in the lab for checking the viability of the isolated

stem cells.• Injection of these cells into the targeted area.• Once inside the targeted location, these stem cells,

differentiate into liver cells by the help of certain growth and immunological factors, example include cytokines.

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Stem Cells Therapy For Liver Cirrhosis The advantages of stem cells involve no dependency on a donor and less chances of rejection and infection as in this case, stem cells are being isolated from the patient’s body itself.

StemGenn Therapeutics, one of the leading Centre in stem cells treatment which deal with various therapies for treating the root cause of the disease using the naturally available stem cells.

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About StemGenn TherapeuticsStemGenn Therapeutics is a leading Cell therapy & Regenerative medicine services company that supports the development and commercialization of cellular therapies and stem cell research.

StemGenn provides cGMP-compliant cell manufacturing and consulting services that address regulatory, financial, technical, process, training and quality system strategies.

Services include a full spectrum of support and consulting related to process and product development, validation, due diligence evaluations, tissue collection, processing, and storage, product manufacturing, distribution and transportation.


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Why StemGenn Therapeutics ?

• As Stem cell have inherent properties to self renew and differentiation into other cell types. They are multi potent and found within our body.• No side effects: as it's found in patient's own tissues or

blood, chances of rejection and infection is negligible.• World class clinicians and experts from Regenerative

Medicine.• Cost Effectiveness: autologous stem cell transplant is

very much affordable.• Non- Surgical Procedure & convenient.• Proven Results.


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The Management & Medical Advisory Board

• Mr. Prabhu Mishra : CEO, Co-Founder• Ms. Richa Jha : MD, Co-Founder• Ms. Shreyashi Gangopadhyay: Director- Business

Development• Dr. Sharda Jain : Chairman- Global StemGenn• Dr. H S Bedi :Director- Cardio Vascular, CMC

Ludhiana• Dr. Satish Totey: Stem Cell Scientist over 35 years

Experiences.• Dr. Roopam Jain: MD Transfusion Medicine, Assoc.

Professor.


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StemGenn Therapeutics Services• Stem cell consulting services.• Stem cell & cord blood bank set up• Regulatory, financial & compliances consultancy• Technical & scientific support for Regenerative Medicine• Stem cell & Bone Marrow Transplant program• Stem cell Therapy • Anti ageing program• Sports Injury and Arthritis : autologous cell implant• Neuro degenerative diseases & Neuro Rehabilitation & Regenerative Therapy.• Business Consulting.• PRP Therapy for Hair Regeneration• Tissue engineering program for Diabetic foot & Maxillofacial application.• Dedicated to services of stem cell therapy & Regenerative Medicine( Repair, Regenerate & Restore).


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For any other query , Please feel free to contact us:Phone : +91 9910596674Email : [email protected] : www.stemgenn.com


stem cells therapy for liver cirrhosis

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