StopPalu Initial Environmental Examination (IEE) Amendment USAID/Guinea Health Program: President’s Malaria Initiative (PMI) Component Contract: 675-A-00-13-00005 Prepared for: United States Agency for International Development President’s Malaria Initiative Prepared by: RTI International 3040 Cornwallis Road Post Office Box 12194 Research Triangle Park, NC 27709-2194

RTI International is dedicated to conducting research and development that improves the human condition by turning knowledge into practice. With a staff of more than 2,500, RTI offers innovative research and technical solutions to governments and businesses worldwide in the areas of health and pharmaceuticals, education and training, surveys and statistics, democratic governance, economic and social development, advanced technology, energy, and the environment. The second largest independent nonprofit research organization in the United States, RTI maintains nine offices in the U.S., five international offices, and one international subsidiary, as well as project offices around the world.

RTI International is a trade name of Research Triangle Institute.

July 2014 This report was produced for review by the United States Agency for International Development. It was prepared by RTI International. The author’s views expressed in this report do not necessarily reflect the views of the United States Agency for International Development or the United States Government.

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INITIAL ENVIRONMENTAL EXAMINATION (IEE) STOP-PALU/GUINEA

Program Number: 675-A-00-13-00005 Country: Guinea Program Elements: Malaria

Funding Period: FY14–FY15

IEE Prepared By: RTI INTERNATIONAL

Current Date: 07 July 2014 Expiration Date: 30 September 2019 IEE Amendment (Y/N): Yes

ENVIRONMENTAL ACTION RECOMMENDED: (Place X where applicable) Categorical Exclusion: Negative Determination: Positive Determination: Negative Determination with conditions: Deferral:

ADDITIONAL ELEMENTS CONDITIONS: ____X______ PVO/NGO: X

SUMMARY OF FINDINGS:

This IEE addresses the establishment of an insectary and entomology laboratory activity in Guinea, under the President’s Malaria Initiative (PMI). This activity is part of the StopPalu Project (675-A-00-13-00005) with malaria funding under PMI. The proposed activity is the establishment of a functional central level insectary and associated entomology laboratory in Guinea and will cover rehabilitation works on pre-existing building space for the facility, training of national staff, technical assistance, initial procurement of laboratory equipment and supplies, and on-the-job training about facility management of the insectary and mentoring of entomological surveillance and monitoring activities. This IEE does not supersede the existing StopPalu IEE that was signed by the Bureau Environmental Officer (BEO) on October 12, 2013 but amends it to include environmental determinations for the establishment of a central-level insectary. The purpose of this IEE amendment is to (1) review the activities linked to the establishment of the proposed insectary/entomology laboratory and (2) provide threshold determinations of environmental impact and the conditions for effective mitigation, to ensure that the proposed activities are environmentally sound.

Pursuant to 22 CFR 216.3 (a)(2)(iii), a Negative Determination, with conditions is hereby recommended for the proposed activities relating to the establishment of central-level insectary and entomology laboratory indicating that the proposed activities will not have a significant effect on the

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environment as long as that the proposed mitigating actions are implemented and effectively monitored.

This IEE amendment on the proposed insectary and entomology laboratory facility also outlines recommended project-level implementation procedures, to assure that the IEE findings and conditions are implemented in project work plans and monitoring and reporting requirements. The procedures described herein are themselves a general condition of approval for the IEE. Their implementation is therefore mandatory: implementation of all recommended mitigations, monitoring, and project-level implementation procedures will be mandatory, contingent on approval of this IEE.

THRESHOLD ENVIRONMENTAL DETERMINATIONS Recommended threshold determinations for activities under this program are summarized below. Section 4 details discussions on the determinations.

1. Categorical ExclusionA Categorical Exclusion is recommended for the following activities except to the extent that the activities directly affect the environment, pursuant to: a) 22 CFR 216.2(c)(2)(i) for activities involving education, training, technical assistance, or

training programs; b) 22 CFR 216.2(c)(2)(ii) for controlled experimentation exclusively for the purpose of

research and field evaluation, which are confined to small areas and carefully monitored; c) 22 CFR 216.2(c)(2)(iii) for activities involving analyses, studies, and academic or research

workshops and meetings; d) 22 CFR 216.2(c)(2)(v) for activities involving document and information transfers;e) 22 CFR 216.2(c)(2)(xiv) for studies, projects, or programs intended to develop the

capability of recipient countries and organizations to engage in development planning.

Specifically, Categorical Exclusions are recommended, per the above (except to the extent that the activities may adversely affect the biophysical environment or human health), for: • Technical assistance, training, and capacity building in standardized entomological

methodologies, insectary and entomology laboratory maintenance, and related data management.

Conditionality The above activities are categorically excluded from environmental scrutiny. However, this IEE recommends that safety related to vector studies be incorporated into all relevant steps along the various steps of utilization and management of an insectary.

2. Negative Determination with ConditionsIn conformity with 22 CFR 216.3(a)(2)(iii), a Negative Determination with Conditions is recommended, for insectary and entomological laboratory establishment. The following mitigation and monitoring conditions associated with the recommended Negative Determination shall be fully complied with.

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2.1 Procurement of equipment and supplies

• Pharmaceutical or chemical products that are procured under this funding will be in smallquantities, as this IEE does not cover the procurement of actual insecticide treated nets orinsecticides for indoor residual spraying. Rather, insecticide use will be limited to the almostnegligible amounts of pesticide that are on strips of paper used in the laboratory to determineinsecticide resistance thresholds in mosquitoes. All products shall be stored in strictcompliance with the manufacturer’s Materials Safety Data Sheet. For disposal of any of thesepharmaceutical or chemical products, either due to expiration or any other reason, it is advisedthat the preferred method of disposal is to return to the manufacturer, unless a disposal facilityis available within the country that meets guidelines in the World Health Organization (WHO)document or other Guidelines for Safe Disposal of Unwanted Pharmaceuticals or ChemicalProducts. If this is not possible (e.g., the expired or spoiled pharmaceuticals or chemicals areconsidered hazardous), the consignee will follow the guidelines in the WHO document or otherGuidelines for Safe Disposal of Unwanted Pharmaceuticals or Chemicals Products.

• Packaging and disposal of all other public health commodities will be treated using theguidelines provided in Environmental Guidelines for Small-Scale Activities in Africa, secondEdition, Chapter 15: Solid Wastehttp://www.usaidgems.org/Sectors/solidWaste.htm

2.2 Rehabilitation of insectary Contractor, in collaboration with the Ministry of Health (MOH), will invite national tenders for the execution of works for refurbishment of the Entomology Laboratory and Insectary, in strict compliance with local Guinea procurement regulations.

• The winning Bidder will embark on rehabilitation of 122, 85 sq. meters, which specificationswill be provided by RTI, in close consultation with PMI and the National Malaria ControlProgram (NMCP). The rehabilitation work will follow environmentally sound principles onconstruction, as provided in the “Small-Scale Construction” chapter of the USAIDEnvironmental Guidelines for Small-scale Activities in Africa, http://www.usaidgems.org

• RTI will obtain PMI approval on the source and technical specifications and supplier ofmaterials intended for this activity prior to implementation.

• The majority of materials used will be procured locally. RTI and/or subcontractor will ensurethat materials do not contain any hazardous materials (e.g., asbestos or lead).

• All materials, including those for electrical and water installations, will be implementedaccording to the code of practice and good construction as applicable in Guinea.

• Demolition and excess construction material will be recycled wherever possible and disposalof unusable material will be done in an environmentally sound manner.

• All equipment necessary for carrying out the rehabilitation works and ensuring adequatesafeguards to prevent destruction of vegetation and soil erosion shall be on site.

• Measures shall be taken to minimize damage to public infrastructures on site (electricity, watersupply drainage). All efforts will be taken to prevent the accumulation of pools of water thatwould promote mosquito breeding.

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• There will be regular maintenance and security of the site during the works until provisionalacceptance of works by the Supervision Authority. The fire extinguishers have to be installedfor potential fire control.

• No lead-based paint should be used. When approved paint is used, (1) it will be stored in well-ventilated premises away from sun or rain to avoid accidental spills or access by unauthorizedpersons; (2) empty cans will be disposed of in an environmentally safe manner away fromareas where contamination of water sources might occur; (3) the empty cans will be destroyedso that they cannot be reused as drinking or food containers; and (4) use of paints with thesolvents, alcohol, and benzene is forbidden.

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• Measures must be taken to ensure that drainage and adequate treatment of waste water fromlaboratory, toilets, and urinals do not contaminate the water supply nor pose threats forbreeding or transmittal of infectious diseases.

• Following completion of the construction, NMCP/University of Conakry (UoC), RTI, and PMIwill jointly inspect the facility, mobilizing relevant experts as may be necessary, to ascertainthat the facility is safe, habitable, and ready for use.

2.3 On-the-job training about use and management of insectary • Entomologist shall be trained to observe maximal vigilance to prevent the escape of

laboratory mosquitoes during transportation to or from the insectary.• RTI, in close coordination with NMCP, shall ensure the incorporation and implementation

of standard practices and protocols for safe handling and disposal of waste from theinsectary, in accordance with MOH Guidelines or other relevant WHO guidelines on thesafe handling of disease vectors.

• Training of facility staff will incorporate environmental health and quality considerations inall relevant areas of insectary management and will form a core component of the qualityassurance and infection prevention approaches at the insectary.

2.4 Entomological monitoring and day-to-day insectary activities • Controlled capture and rearing of local malaria vectors, as well as maintenance of a colony

of fully susceptible laboratory-reared Kisumu strains of Anopheles gambiae s.s. forexperimentation will occur. These vectors will be used exclusively for entomologicalevaluation to understand local malaria transmission and impact of vector controlinterventions on the local vectors and local disease transmission. The safeguards hereindescribed are to prevent or reduce the risk of possible escape of mosquitoes into the generalenvironment.

• Insecticide resistance tests and monitoring using a range of methods (CDC bottle assay,and WHO cone bio-assay) will be part of the insectary operations. Insecticide impregnatedtest papers (which contain a miniscule amount of insecticide) comprising a wide range ofinsecticides which will be used for resistance tests, will be procured and stocked in securestorage.

• The insectary may also procure small amounts of WHO recommended insecticides forcontrolled experiment and trials. Except as provided below, this IEE does not cover theprocurement of pesticides. Activities that entail the promotion or use of pesticides for

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activities involving controlled experimentation exclusively for the purpose of research and field evaluation which are confined to small areas (< 4 ha) and carefully monitored, shall be within the parameters of 22 CFR 216.3(b)(2)(iii) ((Exceptions to Pesticide Procedures). All activities that fall outside of the category of controlled experimentation exclusively for the purpose of research and field evaluation under 22 CFR 216.2(c )(2)(ii) and entail the procurement or use, or both, of pesticides shall be analyzed in accordance with USAID Pesticide Procedures (22 CFR 216.3(b) and no funds shall be obligated or expended for the procurement or use of pesticides unless they are specifically approved through an amendment to this IEE in accordance with 22 CFR 216.3(b).

MONITORING AND GENERAL COMPLIANCE CONDITIONS The IEE findings and conditions shall be implemented as inherent and routine project implementation. The procedures form general conditions of approval for the IEE. Their implementation is therefore mandatory.

Monitoring and general compliance conditions These are mandatory procedures intended to ensure that the IEE findings and conditions are fully implemented.

Coordination with USAID/Guinea Health Teams Consistent with similar establishment of an insectary and entomology laboratory undertaken by RTI under PMI, RTI will work in consultation with the Agreement/Contract Officer’s Representative(s) (A/COR[s]), activity managers, the Mission Environmental Officer (MEO), and as appropriate, the Regional Environmental Advisor (REA) and the Bureau Environmental Officer (BEO), to actively monitor and evaluate any environmental consequences arising during implementation in order to modify or end activities deemed harmful to the environment and human welfare and wellbeing. The close coordination will ensure that:

• New activities at RTI/StopPalu, linked to the insectary/entomology laboratory are covered under an amended IEE before implementation occurs;

• Selection of sub-contractors and/or grantees adequately considers the ability to perform the mandatory environmental compliance requirements contained in this IEE, and ensures appropriate inclusion of environmental compliance and reporting requirements;

• Appropriate budget, resources, qualified staff, equipment, and reporting procedures are contained in proposals to conduct environmental compliance and that mitigation and monitoring measures are conducted as a routine component of program implementation;

• Regular and timely field visits and consultations with PMI take place to jointly assess the environmental impacts of ongoing activities and associated mitigation and monitoring conditions;

• As needed, the delivery of activity-specific environmental training is appropriately facilitated.

Specific responsibilities and requirements for RTI:

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1) Undertake regular site visits to monitor and evaluate activities and environmental impact,as well as the effectiveness of the proposed mitigations measures and Best ManagementPractices (BMPs).

2) Issue quarterly reports to PMI – to include brief updates on the mitigation and monitoringmeasures under implementation and the findings of the environmental monitoring visits.Develop annual performance monitoring plans and work plans as part of annual reportingon StopPalu activities during the fiscal year.

3) As necessary, develop an Environmental Mitigation & Monitoring Tracking System,(“checklist”) to ensure compliance with environmental regulations.

As required by ADS 204.5.4, RTI will monitor ongoing activities for compliance with approved IEE recommendations and modify, or end, activities that are not in compliance. As necessary, USAID/Guinea Health Team shall undertake monitoring visits and ensure that adequate time and resources are available to bring all approved activities into compliance pursuant to this IEE. An amended environmental examination will be prepared should additional activities be added that are not described in this document.

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INITIAL ENVIRONMENTAL EXAMINATION (IEE) INTEGRATED VECTOR MANAGEMENT FOR MALARIA AND OTHER INFECTION DESEASES

Program Number: 675-A-00-13-00005 Country: Guinea Program Elements: Malaria

Funding Period: FY14–FY15

IEE Prepared By: RTI INTERNATIONAL

Current Date: 30 March, 2014 Expiration Date: 30 September 2019 IEE Amendment (Y/N): Yes

1. BACKGROUND AND PROJECT DESCRIPTION

1.1 Background The StopPalu Project cooperative agreement No. 675-A-00-13-00005 was signed on May 16, 2013, with the overall objective of supporting the Government of Guinea (GOG) to achieve the target of reducing malaria-associated mortality by 50%, compared to pre-initiative levels. The project supports enhancement and effective implementation of the National Malaria Strategic Plan, through key intervention areas of long-lasting insecticide-treated net (LLIN) use, intermittent preventative treatment in pregnancy (IPTp), as well as case management, including support for malaria diagnostics and treatment at the health facility and community levels. Consistent with the overall objective, the 2014 PMI Malaria Operational Plan for Guinea aims, among others, to:

• Support the procurement and delivery of LLINs to the district level (mass distribution androutine distribution);

• Conduct entomological monitoring and surveillance of vectors and capacity-building forentomologists; and

• Support monitoring and evaluation (M&E) at the district, regional, and national levels,including routine system strengthening, surveillance, data use for decision making, and periodic household and health facility surveys.

The establishment of a national insectary and entomology laboratory is seen as a priority agenda for FY2014, to enable assessment of the effectiveness of national vector control interventions.

1.2 Purpose and scope of IEE The StopPalu IEE was signed by the Bureau Environmental Officer (BEO) on October 12, 2013. The purpose of this IEE amendment is to review and include environmental determinations for the activities to be implemented in the establishment of the insectary and associated entomology laboratory, as well as the entomological activities that the facility will subsequently support. It is intended to provide threshold determinations of environmental impact and conditions for mitigation, consistent with the approved IEE and the requirements of 22CFR216, ADS 204.5, and ADS 203 for any new activities that were not covered by the original IEE, to ensure that the activities to be

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implemented under insectary and entomology are environmentally sound.

This insectary/entomology laboratory rehabilitation IEE amendment is subordinate to the environmental documentations for the PMI portfolio, including the IVM-PEA. The proposed insectary/entomology laboratory IEE amendment covers technical assistance, training, procurement of equipment and supplies, construction, and on-the-job training/mentoring on use and management of the facility.

The present IEE outlines mandatory project-level implementation procedures, which are aimed at assuring the implementation of the IEE findings and conditions in the annual work plans, monitoring and reporting requirements of the StopPalu Project. These procedures herein described therefore form general conditions for the approval for the IEE.

1.3 Overview of rehabilitation and related activities The following sections cover the sub-activities to be undertaken to ensure adequate national preparation and capacity.

1.3.1 Human resources development and technical assistance StopPalu, in close coordination with Centers for Disease Control and Prevention (CDC), will train staff of the NMCP in (1) insectary and entomology laboratory techniques, (2) proper functioning of an insectary and entomology laboratory, and (3) data management. There is already ongoing hands-on tutoring and mentoring of field entomology technicians and NMCP entomologist by CDC as part of entomological baseline assessments. This follows a 2012 basic entomology training course organized by RTI under a previous USAID-funded IVM Project. In addition, a two-month training in advanced entomology methodologies, including enzyme-linked immunosorbent assay (ELISA)- and polymerase chain reaction (PCR)-based procedures, is anticipated for two NMCP senior entomology staff who will have oversight of the insectary and undertake these advanced evaluations. The advanced training will coincide with the completion of the facility. In close consultation with CDC, the project will provide technical support to the NMCP to develop an entomology monitoring plan and mentor the implementation of the plan.

1.3.2 Rehabilitation of insectary and related laboratory In February 2014, a joint team from RTI/StopPalu, CDC, and the NMCP met with the Vice Chancellor and senior leadership of UOC and together identified a suitably large room/lab spaces less 122, 85 sq. meters. on the second floor of a building on the Conakry campus of the university. The labs will be rehabilitated to house the proposed insectary and associated entomology laboratory. There will be an insectary where laboratory-reared vector colonies will be kept. The entomology laboratory will comprise two sections: a section that will be used for basic work (sorting of vector samples, susceptibility evaluations, etc.) and a more restricted section for biomolecular (ELISA- and PCR-based) evaluations. RTI, in consultation with CDC, has provided technical support for a memorandum of understanding (MOU) between the NMCP and UoC (see Annex B).

In strict compliance with the procurement regulations of GOG as well as applicable USAID regulations, StopPalu will award the contract to a local construction company to undertake the rehabilitation.

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1.3.3 On-the-job training An insectary is used to raise and maintain colonies of wild-caught local mosquito vector(s), as well as fully susceptible species, under laboratory conditions. The activity will support on-the-job training of Guinean staff on use and management of the insectary and laboratory. Table 1 shows entomological study activities that can be carried out in an insectary that will be included and taught in on-the-job and advanced training.

1.3.4 Use and management of insectary As stated above, an insectary will be used to raise and maintain colonies of wild-caught local mosquito vector(s), as well as fully susceptible species, under laboratory conditions. The entomology laboratory will enable standardized evaluations to be conducted on the local vectors to provide insight into critical transmission indices, such as susceptibility/resistance and effectiveness of interventions that are being implemented. The specific activities are presented in Table 1 below.

Table 1: Desirable entomological evaluations of malaria vectors BASIC Entomological evaluations (measured monthly) – Category 1 (i) Night landing catches (indoor & outdoor). Local vectors are observed to study their biting

behaviour. (ii) Pyrethrum spray catches. Malaria vectors in pre-selected houses captured for observation

between 6am and 8am to study entry into rooms over time (blood meal and parity assessments could be studied on the captured vectors – see Category 2 evaluations below).

(iii) Insecticide residual effectiveness (Cone bioassay). The vector knock down potential of insecticide sprayed on major wall surface types (mud, cement, painted or unpainted, wood), as well as that on LLIN surfaces is measured at intervals to study the rate of decay of the insecticide. This is expressed as 24 hour mortality of mosquitoes exposed to sprayed walls for 30 minutes; or 24 hour mortality of mosquitoes exposed to LLINs for 3 minutes.

(iv) Species identification (morphological) and composition. From monthly catches the study will enable the tracking of any changes in species morphology (type) and composition within the year and over the years.

Entomological evaluations – Category 2 Category 2 evaluation on the catches provides insight on effectiveness of an intervention and indicates transmission risk changes in households where the vector control intervention is deployed. The following indicators can be assessed during Category 2 evaluation:

(i) Sporozoite rates (quarterly) – provides insight into risk of getting malaria. (ii) Entomological inoculation rates (quarterly) – measure risk of getting malaria through

infected bite. (iii) Blood meal analysis (half yearly) – provides insight into feeding preference of mosquito

vector. (iv) Parity evaluations (quarterly) – denotes how effective is the intervention . (v) Vector susceptibility evaluation (WHO tube assay methods) – 2x/year for WHOPES-

approved insecticides.

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(vi) Biomolecular assessment of vector insecticide resistance mechanism (annually) – it is anticipated that selected NMCP staff would be appropriately trained on this method and mentored by CDC and RTI to undertake the evaluations.

The insectary will also facilitate insecticide resistance tests and monitoring using a range of methods (CDC bottle assay, and WHO cone bio-assay). Insecticide impregnated test papers comprising a wide range of insecticides which will be used for resistance tests, will be procured and stocked in secure storage.

The insectary may also procure small amounts of WHO recommended insecticides exclusively for controlled experiments and trials (e.g., hut trials to determine residual efficacy of insecticides in order to provide key information to the Government of Guinea). Except as provided below, this IEE does not cover the procurement of pesticides. Activities that entail the promotion or use of pesticides for activities involving controlled experimentation exclusively for the purpose of research and field evaluation which are confined to small areas (< 4 ha) and carefully monitored, shall be within the exceptions to Pesticide Procedures as described in parameters of 22 CFR 216.3(b)(2)(iii). RTI will ensure that all activities that fall outside of the category of controlled experimentation exclusively for the purpose of research and field evaluation under 22 CFR 216.2(c )(2)(ii) and entail the procurement or use, or both, of pesticides shall be analyzed in accordance with USAID Pesticide Procedures (22 CFR 216.3(b) and no funds shall be obligated or expended for the procurement or use of pesticides unless they are specifically approved through an amendment to this IEE in accordance with 22 CFR 216.3(b).

1.4 Implementing partners RTI International is the prime partner for the StopPalu Project. RTI and CDC will provide technical assistance for the establishment of the insectary and associated entomology laboratory. RTI will, through a public bidding process, award a contract to rehabilitate the facility. The bidding and award process will be in strict compliance with the procurement regulations of GOG and consistent with applicable USAID procedures.

2. COUNTRY AND ENVIRONMENTAL INFORMATION

2.1 Guinea Environmental Baseline profile Guinea covers an area of about 245,857 km2 (94,926 mi2) with a total population of about 10.2 million. There are four main geographical regions: the forested jungle regions in the southeast, the Basse-Coté lowlands, the mountainous Fouta Djallon in the middle of the country, and the Sahelian Haute-Guinea to the northeast. The mountains of Guinea are the source for seven major West African rivers, including the Gambia, Niger, and Senegal Rivers, as well as those flowing to Sierra Leone and Côte d'Ivoire. Guinea is home to the UNESCO Strict Nature Reserve. About 60% of the country is covered by forest (dense humid forest, dense dry forest, wooded savanna, and mangroves). Like a majority of countries in the region, Guinea faces significant changing climate patterns, as well as a high rate of deforestation as a result of agriculture. The country has a significant mining sector and is one of the world’s foremost bauxite producers.

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2.2 Locations affected Insectary and laboratory space has been provided by UoC, on its main campus, which will be rehabilitated. The GOG and the MOH, however, have nationwide malaria control activities. Mosquito sample collection will therefore be done in various locations around the country.

2.3 Guinea environmental policies and procedures Guinea is signatory to a number of global conventions, including the Convention on Biological Diversity, the Ramsar Wetlands Convention, Climate Change, Climate Change-Kyoto Protocol, Desertification, Endangered Species, Hazardous Wastes, Law of the Sea, Ozone Layer Protection, Wetlands. Other specific local regulations of relevance include:

• National Action Plan for the Environment (NAPE) (September 1994) • Decree 89-199 codifying impact studies on the environment implementing decree • 89-200 decree on the legal regime of classified installations • 89-201 decree on the preservation of the marine environment against all forms of

pollution

USAID supports the GOG to coordinate and implement sound environmental policies and regulations, in alignment with international conventions. A USAID-funded Program for Environmental Governance in Guinea for Capacity Building and Biodiversity Conservation (PEGG) is supporting the (a) improvement of national capacity to implement and enforce environmental policies, procedures, and best management practices and (b) promote accountability within the Ministry of Environment (MOE). PEGG has identified improvement of national capacity for review of environmental impact statements (EISs) and monitoring of Environmental Management Plans (EMPs) as a priority objective.

2.4 Overview of insectary and entomology study in Guinea The insectary is a prerequisite to effective vector control. It provides a controlled environment to rear mosquitoes for experimentation and monitoring of vector control programs. The NMCP will provide insectary staff who will undergo advanced entomology training under the StopPalu Project, with close coordination with CDC. The training will cover all critical entomological monitoring methodologies, laboratory rearing of mosquitoes, insectary maintenance and relevant laboratory procedures, as well as biosafety precautions. The insectary staff will be under the direct supervision of the NMCP entomologist. Recognizing the broader goal of creating adequate numbers of trained human resource in vector control, and the fact that the insectary/laboratory facility will be located at UoC, the NMCP will offer regulated access to university students with interest in undertaking research in vector control as part of training, workshop, or degree programs related to malaria control or other public health programs. A formal MOU has been established between NMCP and UoC, outlining roles and responsibilities to ensure smooth functioning of the facility (See Annex B). The NMCP will be responsible for all costs associated with the management and maintenance of the insectary and associated entomology laboratory; as necessary, PMI may provide field funds to support activities of the insectary and entomology laboratory to fulfill the objectives of the PMI technical support to the GOG on malaria. Such funding, if provided, will be outlined in the annual MOPs of the PMI for Guinea. When suitable colonies of test vectors are established in the insectary and the requisite training is completed, this facility will serve as the pivot of national entomology monitoring activities, coordinating field-level activities. The basic entomological evaluations (Category 1) can include collections of

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mosquitoes from different parts of Guinea, which will be initially processed on location in the field, and subsequently at the entomology laboratory for species abundance and identification. Insecticide resistance testing will be conducted annually as part of monitoring evaluations of the effectiveness of LLINs and other vector control interventions. All entomological data generated from M&E activities will be managed by the NMCP to inform decisions on vector control. Such data will also be accessed by PMI and its implementing partners to inform ongoing PMI priorities on technical support to GOG.

3. EVALUATION OF PROJECT ISSUES WITH RESPECT TO ENVIRONMENTAL IMPACT POTENTIAL

A functional insectary is needed to effectively assess changes to local vector population structure/dynamics and disease eco-epidemiology that arise from the introduction of vector control interventions such as LLINs or indoor residual spraying. Vector control interventions may reduce or increase resistance of local vector populations to insecticides and change the routes of disease transmission (e.g., indoor versus outdoor). Changes in natural ecological factors such as rainfall, deforestation, and other human activities could impact species composition and succession. The training and technical assistance activities related to the proposed establishment of a functional central-level insectary and associated entomology laboratory on the UoC campus will not have direct adverse environmental impacts. However, other related activities such as the procurement of equipment supplies, construction, and management of the insectary may impact the biophysical environment if mitigation measures are not adequately considered. The following sections review the potential environmental impacts of proposed insectary/entomology laboratory activities.

3.1 Technical assistance and training of human resources The activities anticipated – technical assistance, capacity building, and training workshops related to establishing the facility – have no significant adverse environmental impact and fall under the categorically excludable activities of US Reg. 216. Any training or technical assistance that will involve the use or manipulation of insecticides or medical material will require appropriate disposals in conformity with Reg. 216 compliance requirements outlined in other IVM-PEA, as well as existing national regulations.

3.2 Procurement of equipment and supplies There are no significant adverse environmental impacts associated with the procurement of entomological equipment and procurement of building materials. However, used supplies requiring proper disposal and/or over-procurement of materials could be classified as negative determination with conditions (also refer to Section 3.4).

3.3 Construction of insectary The establishment of the insectary/entomology laboratory facility will include the rehabilitation of pre-existing room/laboratory spaces on the second floor of a building on the UoC campus in Conakry. An MOU is being established between the NMCP and UoC that spells out roles and responsibilities of the two institutions to facilitate smooth functioning of the facility. RTI/StopPalu will award the contract to a local construction company to undertake the rehabilitation work, in strict compliance with the procurement regulations of GOG and applicable USAID regulations.

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Rehabilitation of infrastructure such as the insectary poses potential direct, indirect, and ancillary adverse environmental risks, depending on local circumstances, including:

• Damage to sensitive or valuable ecosystems from construction of infrastructure, associated temporary worker dwelling, or construction of storage units for personnel or equipment;

• Removal of vegetation and/or compaction of the soil and grading of the site, altering local drainage patterns in the immediate vicinity. However, because the facility is to be integrated into an existing campus infrastructure, no significant changes are envisaged;

• Removal of natural land cover, excavation, extraction of construction materials, and other construction-related activities that will result in soil erosion is anticipated. [None is expected to occur in this specific case.];

• Contamination of groundwater and surface water supplies through improper disposal of human and other biological wastes is anticipated during the construction period. [None is expected in this case.];

• Potential contamination of ground and surface water supplies through improper disposal or handling of toxic materials e.g., solvents, paints, vehicle maintenance fluids, coolant, and diesel fuel);

• Adverse social impacts due to displacement of local inhabitants, influx of outside workers, inequitable distribution of economic benefits of construction, etc. [None is expected to occur in this case.];

• Spread of disease through migration of construction workers from other regions, especially sexually transmitted diseases such as HIV/AIDS. [Because the rehabilitation work is very limited, this activity is not expected to contribute to sexually transmitted disease transmission.];

• Damage to aesthetics of site/area.[ None expected in this case.]; • Improper extraction of construction materials such as wood, stone, gravel, or clay that

damages terrestrial ecosystems (e.g., wood may come from relatively intact or natural forests);

• Use of toxic materials during construction.

Construction of insectary must be accompanied by an Environmental Mitigation and Monitoring Plan (EMMP). Guidelines and Checklists for Small-Scale Construction and Renovation Activities can be found at http://www.usaidgems.org/: Small-scale Construction.

3.4 Use and management of insectary The vectors that will be housed in the insectary are already available in the general environments. Hence there will be no introduction of foreign vectors that will pose new disease risks. Recognizing, however, that the insectary will have ongoing use, this IEE must cover all potential scenarios. Escape of vectors can happen during transportation to or from the insectary. Insectary staff must assure full application of standardized safeguards to eliminate escape of test mosquito vectors. Staff and all handlers of insecticides within the insectary and entomology laboratory will ensure appropriate protection through use of appropriate personal protection equipment and release into the general environment (the air outside of intended closed areas, water, and soil). The insectary will also be used to study resistance mechanisms when PCR and ELISA equipment and skills are available. The PCR is a DNA test used to identify sub-species within a mosquito species, as well as gene alleles that enable insects to survive insecticide specifications and concentrations that normally should kill them. The ELISA test is used to assess whether mosquitoes are infected

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with plasmodium, as well as the blood meal type (human, animal) that the vector takes. Appropriate and standardized laboratory biosafety measure shall be instituted to reduce any risk for the blood products.

4. RECOMMENDED DETERMINATIONS, MITIGATIONS & CONDITIONS This IEE recommends threshold decisions and conditions for implementing the establishment of a functional insectary based on the review under Section 3. The environmental screening and review procedures described here do not substitute the host country’s own environmental laws and policies where such exist.

For consistency and completeness with relevant USG/USAID regulations, portions of the following sub-sections have been culled/summarized from previous IEE documents prepared by RTI for similar PMI-funded activities to establish insectary/entomology laboratory facilities.

4.1 Categorical Exclusions A Categorical Exclusion is recommended for the following activities except to the extent that the activities directly affect the environment, pursuant to:

a) 22 CFR 216.2(c)(2)(i) for activities involving education, training, technical assistance, or training programs;

b) 22 CFR 216.2(c)(2)(ii) for controlled experimentation exclusively for the purpose of research and field evaluation which are confined to small areas and carefully monitored;

c) 22 CFR 216.2(c)(2)(iii) for activities involving analyses, studies, and academic or research workshops and meetings;

d) 22 CFR 216.2(c)(2)(v) for activities involving document and information transfers; e) 22 CFR 216.2(c)(2)(xiv) for studies, projects, or programs intended to develop the capability

of recipient countries and organizations to engage in development planning. f) 22 CFR 216.3(b)(2)(iii) ((Exceptions to Pesticide Procedures). For the promotion or use of

pesticides for activities involving controlled experimentation exclusively for the purpose of research and field evaluation confined to small areas (< 4 ha) and carefully monitored.

Specifically, Categorical Exclusions are recommended, per the above (except to the extent that the activities may adversely affect the biophysical environment or human health), for: • Technical assistance, capacity building, and training workshops in the areas of entomological

techniques, entomology and insectary laboratory maintenance, and data management.

Requirement The above activities are categorically excluded from environmental scrutiny. However, this IEE nevertheless recommends that safety related to vector studies be incorporated into all relevant steps along the various steps of utilization and management of an insectary.

4.2 Negative Determinations with Conditions A Negative Determination with Conditions is recommended, pursuant to 22 CFR 216.3(a)(2)(iii) for insectary activities that have potential for negative impact on the environment. The following mitigation and monitoring conditions associated with the recommended Negative Determination shall be implemented:

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4.2.1 Procurement of equipment and supplies

• All pharmaceutical or chemical products procured under this funding will be advised to store the product according to the information provided on the manufacturer’s Materials Safety Data Sheet. These are supplied by the manufacturer and can also be found on the internet. If disposal of any of these pharmaceutical or chemical products is required, due to expiration date or any other reason, the consignee will be advised that the preferred method of disposal is to return to the manufacturer. If this is not possible (e.g., the expired or spoiled pharmaceuticals or chemicals are considered hazardous), the consignee will follow the guidelines in the WHO document or other Guidelines for Safe Disposal of Unwanted Pharmaceuticals or Chemicals Products.

• Packaging and disposal of all other public health commodities will be treated using the guidelines provided in Environmental Guidelines for Small-Scale Activities in Africa, 2nd Edition, Chapter 15: Solid Waste http://www.usaidgems.org/.

4.2.2 Rehabilitation of Insectary 1 RTI, in collaboration with NMCP, will invite public tenders for the execution of works for

refurbishment of the insectary and entomology laboratory, in strict compliance with local Guinea procurement regulations. The qualified bidder will be awarded the contract by RTI International.

2 The process of refurbishment has to follow the small-scale guidelines on construction which can be downloaded onhttp://www.usaidgems.org/

3 The winning bidder will embark on rehabilitation of the facility, which will cover a total surface area of 122, 85 sq. meters. The works will be conducted following environmentally sound principles relevant for construction work, as provided in the “Small-Scale Construction” chapter of the USAID Environmental Guidelines for Small-Scale Activities in Africa, which can be found at www.encapafrica.org.

4 RTI is responsible for supplying all materials intended for the execution of this project. RTI will submit their source for materials and the supplier’s technical specifications to PMI/Guinea and NMCP for approval before implementation of rehabilitation works.

5 The majority of materials used will be bought locally, and the contractor and/or subcontractor will ensure that the materials fulfill the requirements of the user and do not contain any hazardous materials (e.g., asbestos or lead).

6 All materials, including those for electrical and water installations, will be implemented according to the code of practice and good construction as applicable in Guinea.

7 Demolition and excess construction material will be recycled wherever possible, and disposal of unusable material will be done in an environmentally sound manner.

8 The contractor will bring to the site all equipment necessary for carrying out the works and ensure proper safeguards to prevent destruction of vegetation and soil erosion. The pathways have to be managed in accordance with sound environmental practices.

9 Measures must be taken to minimize any damage of public infrastructures that exist on the site (electricity, water supply, drainage) and the possibility of water retention that would be ideal for mosquito breeding.

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10 The contractor shall ensure regular maintenance and guarding of the site during the works until provisional acceptance of works by the supervision authority. The fire extinguishers have to be installed for potential fire control.

11 No lead-based paint should be used. When approved paint is used, (1) it will be stored in well-ventilated premises away from sun or rain so as to avoid accidental spills or consumption by children; (2) empty cans will be disposed of in an environmentally safe manner away from areas where contamination of water sources might occur; (3) the empty cans will be broken or punctured so that they cannot be reused as drinking or food containers; and (4) use of paints with solvents, alcohol, and benzene is forbidden.

12 Any pesticides used for trials must comply with Reg. 2.16 and USAID regulation documents, including the IVM-PEA.

13 Measures must be taken to ensure that drainage and adequate treatment of waste water from laboratory roofing, toilets, and urinals does not contaminate the water supply nor pose threats for breeding or transmittal of infectious diseases. A treatment of waste water has to be established according to the Guinea regulations.

14 Following completion of the construction, NMCP, UoC, RTI, and PMI will jointly inspect the facility, mobilizing relevant experts as may be necessary to ascertain that the facility is safe, habitable, and ready for use.

4.2.3 On-the-job-training about use and management of insectary • The entomologists and laboratory technicians will be trained to be vigilant for possibilities of

escape of mosquitoes during transportation or possible escape from the laboratory and insectary. The training will ensure the workers have the required competencies and skills related to the relevant processes and evaluations that are to be carried out at the facility. The laboratory and insectary staff will be under the direct supervision of a qualified entomologist in the NMCP. As necessary, the NMCP will establish strategic collaboration with other country-level or international partners such as the International Centre of Insect Physiology and Ecology (ICIPE) and Kenya Medical Research Institute (KEMRI), where similar facilities are operational, to assure knowledge/skills transfer.

• The sentinel sites will be manned by trained field technicians who will support vector collections in the field. These technicians will have onsite refresher training within the national health program and through mentoring by RTI and CDC to ensure ongoing competency.

• The NMCP shall ensure that good laboratory practice and standard operating procedures (SOPs) for proper functioning of the insectary and entomology laboratory are adhered to at all times.

• Environmental health and quality considerations must be incorporated during training into all relevant steps of the laboratory management process as part of the quality assurance and infection prevention approaches.

4.2.4 Use and management of insectary • The insectary will be used to raise and maintain colonies of wild-caught local mosquito

vector(s), as well as fully susceptible species, under laboratory conditions. The controlled catching and raising of vectors for experimentation will exclusively be for the purpose of

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entomological evaluation, following procedures and controls that will reduce the risk for possible escape of mosquitoes into a different habitat.

4.3 Monitoring and general compliance conditions These are mandatory procedures intended to ensure that the IEE findings and conditions are fully implemented.

4.3.1 Coordination with USAID/Guinea Health Teams Consistent with similar activities undertaken by RTI under PMI, RTI will work in consultation with the A/COR(s), activity managers, the MEO, and, as appropriate, the REA and the BEOs to actively monitor and evaluate any environmental consequences arising during implementation in order to modify or end activities deemed harmful to the environment and human welfare and wellbeing. The close coordination will ensure that:

• New activities at RTI/StopPalu linked to the insectary/entomology laboratory are covered under an amended IEE before implementation occurs;

• Selection of sub-contractors and/or grantees adequately considers the ability to perform the mandatory environmental compliance requirements contained in this IEE, and ensures appropriate inclusion of environmental compliance and reporting requirements;

• Appropriate budget, resources, qualified staff, equipment, and reporting procedures are contained in proposals to conduct environmental compliance and that mitigation and monitoring measures are conducted as a routine component of program implementation;

• Regular and timely field visits and consultations with PMI take place to jointly assess the environmental impacts of ongoing activities and associated mitigation and monitoring conditions.

• As appropriate, the delivery of activity-specific environmental training to the contractors and subs is facilitated.

4.3.2 Specific responsibilities and requirements for RTI/StopPalu 1. Undertake regular site visits to monitor and evaluate activities and environmental impact,

as well as the effectiveness of the proposed mitigations measures and Best Management Practices (BMPs).

2. Issue quarterly reports to PMI – to include brief updates on the mitigation and monitoring measures under implementation and the findings of the environmental monitoring visits.

3. Include an annual environmental mitigation and monitoring report of activities undertaken during the fiscal year in the annual performance monitoring plans and annual work plans of RTI/StopPalu.

4. Incorporate provisions that stipulate an annual environmental monitoring report linked to any fund transfers from implementing partners to other organizations (sub-partners); and that activities to be undertaken will be within the scope of the environmental determinations and recommendations of this IEE. This includes assurance that any mitigating measures required for those activities be followed.

5. As necessary, develop an Environmental Mitigation & Monitoring Tracking System, (“checklist”) to ensure compliance with environmental regulations.

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RTI/StopPalu will monitor ongoing activities for compliance with approved IEE recommendations, and modify or end activities that are not in compliance. As necessary, USAID/Guinea Health Team shall ensure that adequate time and resources are available to bring all approved activities into compliance pursuant to the requirements of this IEE. An amended environmental examination will be prepared should additional activities be added that are not described in this document, and for which a gap is identified.

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4.3.3 Summary of Environmental Monitoring and Mitigation Plan

Activity 1: Procurement of Supplies Potential Environmental Impacts: harvest of construction materials can damage the aquatic ecosystems through erosion and siltation; harm terrestrial ecosystems via harvesting of wood, sand, or other natural products; and spread vector-borne diseases when stagnant water accumulates in active or abandoned quarries or borrow pits and breeds insect vectors. Procurement of poor quality materials or over-quantification of materials, including procurement of laboratory supplies that are close to expiry date, will all lead to generation of waste materials. Waste minimization should start with the procurement process in that only the right quantities of usable materials are procured. Packaging materials and any solid wastes generated will have to follow appropriate disposal methods to avoid contaminating ground water and the general environment.

IEE Condition Specific mitigation actions to

implement the condition How implementation will be verified

(Monitoring indicators)

Timeframe for monitoring and

reporting

Person responsible for implementing

mitigation Appropriate sourcing of building materials

• Identify the most environmentally sound source of materials within budget

Number of site monitoring visits to the construction site

During implementation

COP

• Train suppliers to take care of environment

Number of people trained Before commencement

COP

Prevent oversupply and procurement of outdated stock

Ensure that procurement is based on the right quantification of the need

Expert review of the quantities proposed for procurement

Before procurement COP

Set up committee to approve procurement plans

Committees set up Include supervision report in quarterly report

COP

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Activity 2: Rehabilitation of Insectary Potential Environmental Impacts: Rehabilitation work may involve demolishing some old sections of the existing building, which will generate solid wastes that can contaminate the environment, and the noise and dust may bother neighbors, including affecting their health.

• Excavation work may cause erosion, siltation, changes in natural water flow, and/or damage to aquatic ecosystems when excavated soil is piled inappropriately. • Construction work may cause people to camp elsewhere away from their homes, increasing the risk of introduction of new behaviors or spread of communicable

diseases. • If renovation includes addition of toilets facilities, there is health risk to health and environment if not constructed to standard design. • Workers may be exposed to hazardous substances during construction, e.g., dust, hazardous paints.

IEE Condition/ Aspect Specific mitigation actions to

implement the condition

How implementation will be verified

(Monitoring indicators)

Timeframe for monitoring and

reporting

Person responsible for implementing

mitigation Solid wastes from the demolition of some sections of the building need to be disposed of appropriately.

• Recover all reusable material, e.g., bricks for reuse on the same building

• Dispose of earth material where potential for contamination of surface and groundwater is small (e.g., use as roadbed)

• Number of monitoring visits • Written report on how the

waste materials have been disposed

During implementation

COP

Some areas on the surrounding may be excavated.

• Minimize the need for excavation where possible.

• Cover pile with plastic sheeting, prevent runoff

• Place fence around excavation

Site monitoring or Inspection reports

During implementation

COP

Construction may involve relocation of people and camping.

• Use local labor for rehabilitation work to minimize the need for camping

• Keep camp size to a minimum • Construction team will be trained

to preserve as much vegetation as possible

• Team will as much as possible use existing sanitary facilities

Verified during monitoring visits During implementation

COP

Minimize exposure of workers to hazardous substances

• All construction workers have to use personal protective equipment (PPE) (overall, hard hat, dust mask, construction shoes, etc.)

Monitoring Report should indicate whether PPEs were used

During implementation

COP

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Activity 2: Rehabilitation of Insectary Potential Environmental Impacts: Rehabilitation work may involve demolishing some old sections of the existing building, which will generate solid wastes that can contaminate the environment, and the noise and dust may bother neighbors, including affecting their health.

• Excavation work may cause erosion, siltation, changes in natural water flow, and/or damage to aquatic ecosystems when excavated soil is piled inappropriately. • Construction work may cause people to camp elsewhere away from their homes, increasing the risk of introduction of new behaviors or spread of communicable

diseases. • If renovation includes addition of toilets facilities, there is health risk to health and environment if not constructed to standard design. • Workers may be exposed to hazardous substances during construction, e.g., dust, hazardous paints.

IEE Condition/ Aspect Specific mitigation actions to

implement the condition

How implementation will be verified

(Monitoring indicators)

Timeframe for monitoring and

reporting

Person responsible for implementing

mitigation • No lead-based paints will be used

on the facility • Painters need to be in full PPE

(overall, mask, appropriate shoes) • Empty paint containers will have to

be punctured before being appropriately disposed of

Bills of quantity will indicate what type of paint will be procured and will have to be approved by committee

Reported in Quarterly reports

Activity 3: Use and Management of Insectary Potential Environmental Impacts: The insectary will be used to raise and maintain colonies of wild-caught local mosquito vector(s), as well as fully susceptible species, under laboratory conditions. The accidental release of these colonies and/or accidental exposure of these colonies to plasmodium may endanger the workers and surrounding communities as well as potential to the biological species in the area. Tight procedures and controls will have to be used to reduce the risk for possible escape of mosquitoes into a different habitat.

IEE Condition Specific mitigation actions to

implement the condition How implementation will be verified

(Monitoring indicators)

Timeframe for monitoring and

reporting

Person responsible for implementing

mitigation Prevent accidental release of the laboratory mosquito colonies into the surrounding environment

• Adopt tight insectary procedures, good laboratory practices, and controls, including restricting access by unauthorized personnel

Availability of written standard operational procedures

During implementation

COP

• Train technicians on insectary best management practices

Number of people trained During implementation

COP

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ANNEX A DRAFT MEMORANDUM OF UNDERSTANDING

BETWEEN

THE GOVERNMENT OF GUINEA

REPRESENTED BY THE NATIONAL MINISTRY OF HEALTH

(NATIONAL MALARIA CONTROL PROGRAM)

AND

RESEARCH TRAINGLE INSTITUTE

(REPRESENTED IN GUINEA BY THE STOPPALU PROJECT)

FOR

THE ESTABLISHMENT OF A PMI-FUNDED INSECTARY AND

ASSOCIATED ENTOMOLOGY LABORATORY IN SUPPORT OF MALARIA

PREVENTION AND CONTROL IN GUINEA

A-1

Preamble

The Government of the Guinea, represented by the Honorable Minister of Health, hereinafter, referred to as “The Government of Guinea,” and Research Triangle Institute, a not-for-profit corporation organized and existing under the laws of North Carolina, USA with a principal place of business at Research Triangle Park, North Carolina, USA, hereinafter referred to as “RTI International.”1

Guinea is one of the beneficiaries of the US President’s Malaria Initiative (PMI). The GOG and PMI share a common interest to prevent and control malaria in Guinea. Further to this interest the parties wish to strengthen national entomology capacity to enable cost-effective malaria prevention and control. An insectary and associated laboratory is to be established on the main campus of the University of Conakry, in Conakry, to serve as a fulcrum for entomology surveillance and monitoring.

THE PARTIES AGREE AS FOLLOWS:

Article One: Objective of the MOU The purpose of this Memorandum of Understanding ("MOU") is to outline, in general terms, the roles and responsibilities of partners (GOG and RTI) in establishing the insectary and associated entomology laboratory and subsequent mechanism for effective and ongoing management/maintenance of the facility to sustain its purpose of supporting entomological monitoring and surveillance activities for malaria prevention and control.

Article Two: Responsibilities of RTI International As the implementing partner of PMI, RTI International, represented in Guinea by the StopPalu Project, will:

a) In close coordination with the MOH/GOG and PMI, provide field oversight and technical, logistical, and operational support for the rehabilitation of an insectary and associated entomology laboratory on the main campus of the University of Conakry in Conakry, Guinea.

b) Ensure that the selected building subcontractor that will be hired in full compliance with relevant national and USAID regulations rehabilitates the said insectary and associated laboratory in strict compliance with the architectural designs.

c) In close consultation with PMI and MOH/GOG, provide as required and authorized by PMI, appropriate training for persons identified by MOH/GOG as staff of the said insectary and associated entomology laboratory. Such training will ensure that the insectary becomes fully functional and credible.

1 RTI International is a trade name for Research Triangle Institute

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d) As appropriate, RTI may pursue strategic collaboration with other country-level or international partners such, to achieve the common objectives of the MOH/GOG and PMI. Any such partnership arrangement will be with prior consent of MOH/GOG and PMI.

e) Oversee the installation of all procured equipment (via the RTI/StopPalu Project and supplied by CDC) and in close coordination with CDC, provide the requisite training to the staff of the insectary and laboratory to adequately use and maintain the procured equipment.

f) Ensure that all appropriate country approvals are obtained for any activity. The activity is subject to required approvals/authorizations as well as relevant funding by PMI or any other partner subject to consent conditions of Article Two (d) above.

g) Provide ongoing technical support for entomological monitoring and surveillance activities arising from and linked with the commonly shared objectives of MOH/GOG and PMI for malaria prevention and control in Guinea. This will include technical support for evaluating and analyzing results obtained and, as may be necessary, guidance on the appropriate utilization of those results.

Article Three: Responsibilities of MOH/GOG MOH/GOG will have the following role and responsibilities:

a) MOH/GOG will assist RTI in obtaining all relevant country-level authorization to undertake the rehabilitation of the insectary and associated entomology laboratory, as well as any other related activities towards the commonly shared goal as agreed to with PMI and captured in the PMI Malaria Operational Plans for which RTI/StopPalu Project is assigned, and/or with RTI as captured in the annual plan of activities by RTI/StopPalu Project, consistent with overall Malaria Operational Plans.

b) MOH/GOG will have ongoing responsibility for the management and maintenance of the insectary and associated entomology laboratory and, to the best of its abilities, ensure continued functionality of the infrastructure to enable ongoing utility toward the shared goals of preventing and controlling malaria in Guinea.

Further to this: i. NMCP/GOG will provide staff for the insectary and associated entomology laboratory. The

NMCP staff will be under the direct supervision of the NMCP Entomologist and will participate in relevant training provided by RTI, PMI, and potential partners [ref. Article Two (d)] aimed at developing requisite competencies to adequately run the insectary and laboratory and conduct standardized entomological monitoring and surveillance activities, including associated data management.

ii. NMCP/GOG will establish a robust scheme for monitoring compliance at the facility involving, but not limited to, annual or twice annual inspections to confirm the continued integrity of containment measures and adequacy of practices in the light of any changes in entomological methodologies and protocols.

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Article Four: Effective Date, Term, Amendment, and Termination a. Effective Date. The terms of this MOU will become effective as of the date signed by the

parties.

b. Term. This MOU shall be effective for a period of 3 years from the effective date unless extended by mutual agreement.

c. Amendment. This MOU represents the complete terms and understanding of the parties, and no other agreements exist between the parties except for those expressly stated herein. This MOU may be amended by written notice of either party, which expressly identifies itself as a part of this agreement and is signed by an authorized representative of each of the parties.

d. Termination: All or any part of the commitment to be provided by each party hereunder may be terminated by either party after giving to the other a thirty (30) days’ written notice or upon the termination of the relevant and overarching agreement between PMI and GOG with regards to the period of PMI support to GOG.

IN WITNESS WHEREOF, this MOU has been executed by the parties herein: The Parties: On Behalf of the On Behalf of the Government of Guinea Research Triangle Institute Authorized signatory: Authorized signatory: (Name) Richard Riethinger Director, Vice President and Lead National Malaria Control Program Global Health Division Ministry of Health RTI International

Date:…………………………… Date:………………………….

A-4

ANNEX B

MEMORANDUM OF UNDERSTANDING

BETWEEN

THE GOVERNMENT OF GUINEA

REPRESENTED BY THE NATIONAL MINISTRY OF HEALTH

(NATIONAL MALARIA CONTROL PROGRAM)

AND

UNIVERSITY OF CONAKRY

FOR

THE ESTABLISHMENT OF A PMI-FUNDED INSECTARY AND

ASSOCIATED ENTOMOLOGY LABORATORY IN SUPPORT OF MALARIA

PREVENTION AND CONTROL IN GUINEA

B-1

Preamble This Memorandum of Understanding (MOU) is hereby established between the Ministry of Health Guinea, represented by the National Malaria Control Program hereinafter, referred to as “NMCP,” and the University of Conakry, hereinafter referred to as “UOC.” GOG is revamping national efforts to scale up effective malaria prevention and control, consistent with the 2013–2017 National Policy and strategic document on malaria. In support of the broad range of efforts by the Government of Guinea in malaria control, the US President’s Malaria Initiative (USAID/PMI), through its implementation partner, the Research Triangle Institute (RTI/StopPalu), is partnering to strengthen the national entomology capacity. A sub-activity of the partnership is to establish a vector control and entomology laboratory facility and associated insectary on the main campuses of UOC in Conakry. Further to the above, NMCP and UOC have jointly identified a suitable laboratory space for the proposed insectary and associated entomology laboratory. This MOU spells out the collaborative arrangements between NMCP and UOC on required rehabilitation of the existing laboratory space allocated and ongoing functioning of the facility to support of the national efforts at malaria prevention and control. THE PARTIES AGREE AS FOLLOWS: Article One: Objective of the MOU The purpose of this MOU is to outline, in general terms, the roles and responsibilities of partners, the NMCP and the UOC, in establishing a vector control and entomology laboratory and associated insectary, and subsequent mechanism for assuring effective and ongoing management/maintenance of the facility to support entomological monitoring and surveillance activities of the NMCP for malaria prevention and control in Guinea.

Article Two: Responsibilities of the NMCP As the primary user of the refurbished facility, the NMCP will:

• Have oversight and unrestricted access to the facility both during the rehabilitation and running of the facility.

• Ensure that all appropriate approvals are obtained for any activity related to the refurbishment of the facility.

• Ensure that the selected building Contractor, refurbishes the said laboratory in strict compliance with the architectural design approved for the facility.

• In close coordination with the UOC, provide direct oversight and technical, logistical, and operational support for the refurbishment of the laboratory and associated entomology laboratory at the UOC campus in Conakry. The rehabilitation will include provision of pump for the supply of potable water to the facility.

• Upon completion of rehabilitation, and jointly with USAID/PMI, RTI, and UOC, inspect the facility, mobilizing relevant expertise as may be necessary, to ascertain that the facility is safe, habitable, and ready for use.

B-2

• Coordinate closely with PMI, RTI/StopPalu, and other partners as may be necessary to ensure appropriate training for persons identified by the NMCP and the UOC to ensure that the facility becomes fully operational.

• Coordinate closely with PMI, RTI/StopPalu, and other partners as may be necessary to provide adequate equipment and supplies to enable identified surveillance and monitoring activities.

• After the completion of the project, provide ongoing technical and financial support for entomological monitoring and surveillance activities as outlined in the national entomological surveillance and monitoring framework.

Article Three: Responsibilities of the UOC The UOC will have the following roles and responsibilities:

• In coordination with NMCP, PMI, and RTI/StopPalu, identify suitable location to house the proposed insectary and associated entomology laboratory.

• Assist NMCP in obtaining all relevant authorization to undertake the refurbishment of the laboratory space, as well as any other related activities toward the shared goal of preventing and controlling malaria in Guinea.

• Provide unrestricted access to the NMCP, and with the consent of the NMCP, technical assistance from USAID/PMI and RTI/StopPalu to the facility, to support malaria control program and monitoring and evaluation.

• Support NMCP to ensure proper management and maintenance of the laboratory, provide electricity and water required and, to the best of its abilities, ensure continued functionality of the infrastructure to enable ongoing utility toward the shared goals of preventing and controlling malaria in Guinea.

• Establish a scheme for monitoring compliance at the facility involving regular inspections to confirm the continued integrity of containment measures and adequacy of practices in entomological methodologies and protocols.

• Provide ongoing security at the facility within the campus.

• In collaboration with NMCP, UOC will offer students of the University with interest in undertaking research in vector control as part of training, workshop, or degree programs related to malaria control or other public health programs, controlled access to the facility for such research, with a broader medium- to long-term goal of building the overall national capacity for vector control.

B-3

Article Four: Effective Date, Term and Amendment a. Effective Date: The terms of this MOU will become effective as of the date signed by the

parties.

b. Term: This MOU is indefinite unless terminated by mutual agreement.

c. Amendment: This MOU represents the complete terms and understanding of the parties and does not nullify or contradict other existing agreements between the parties, except for those expressly stated herein. This MOU may be amended by written notice of either party, which expressly identifies itself as a part of this agreement and is signed by an authorized representative of each of the parties.

d. Termination: All or any part of the commitment to be provided by each party hereunder may be terminated by either party after giving to the other a thirty (30) days’ written notice.

This MOU is not intended to be legally binding and does not create any contractual or other legal obligations on either party; nor will the parties be subject to any legal liability resulting from non-performance of any provisions of this MOU. The parties, however, undertake to act in good faith with respect to each other and to adopt reasonable measures to ensure the realization of the objectives of this MOU.

IN WITNESS WHEREOF, this MOU has been executed by the parties herein: The Parties: On Behalf of the On Behalf of the Government of Guinea Research Triangle Institute Authorized signatory: Authorized signatory: (……Name………………) (…………..Name) Director, (position) National Malaria Control Program University of Conakry Ministry of Health Date:…………………………… Date:………………………….

B-4