striated skeletal muscular tissue. functions movement heat stabilization
TRANSCRIPT
STRIATED SKELETALMUSCULAR TISSUE
FUNCTIONS
• Movement
• Heat
• Stabilization
TYPES
Striated Skeletal
Voluntary
Striated Cardiac
Involuntary
Visceral Smooth
Involuntary
PROPERTIES
• Contractibility
• Excitability
• Extensibility
• Elasticity
FASCIA
• Tendon of Origination
• Epimysium
• Perimysium
• Endomysium
• Tendon of Insertion
MYOFIBER STRUCTURE
• Sarcolemma• Sarcoplasm• Sarcoplasmic Reticulum
– Transverse Tubule
– Triad
– T Tubule
– Terminal Cisterna
• Multinuclear• Mitochondria• Myofibrils
MYOFIBER MYOFILAMENTS• Contractile Proteins
Actin
Myosin
• Regulatory ProteinsTroponin
Tropomyosin
• Structural ProteinsTitin
Nebulin
Myomesin
Dystrophin
SARCOMERIC AREAS
• Z Disc
• I Band
• A Band
• H Zone
• M Line
• I Band
• Z Disc
METABOLISM OF MYOFIBER
• Anaerobic Respiration– Glycolysis
• 2 ATP’s / Glucose• 2 Trioses / Glucose• 2 NADH2 / Glucose
AEROBIC RESPIRATION
• Transition Reaction– 2 Pyruvic Acid / Glucose– 2 NADH2 / Glucose
• Citric Acid Cycle– 2 ATP’s– 2 FADH2 / Glucose– 6 NADH2 / Glucose
• Electron Chain Transport
BLOOD SUPPLY
• Myofiber– Capillary
• Arterial• Venous
NEUROMUSCULAR JUNCTION
• Somatic Motor Neuron– Dendrites– Cell Body– Axonic Hillock– Teleodendria– Synaptic End Bulb– Synaptic Vacuole– Exocytosis– ACH– Synapsis– Diffusion
NEUROMUSCULAR JUNCTION
• Myofiber– Sarcolemma– Ach Receptor– Transverse Tubule – Na+ Gates Open– Na+ Influx– Transverse Tubule– Triad
NEUROMUSCULAR JUNCTION
• Myofiber– Triad– Terminal Cisternae– Ca+2 Gates Open– Ca+2 Sarcoplasmic Diffusion– Activated Troponin– Activated Tropomyosin– Troponin Tropomyosin Complex– Exposed Actin
NEUROMUSCULAR JUNCTION
• Myofiber– Ca+2 Sarcoplasmic Diffusion– Myosin Cross Bridges– ATP Myosinases– Dephosphorylation of ATP– Diphosphate Bonds Broken– Energy Released– ADP and Free High Energy
NEUROMUSCULAR JUNCTION
• Myofiber– Actin-Myosin Lock Up– Myomesin Pulls on Myosin– Myosin Pulls Actin– Myosin and Actin in H Zone– H Zone Disappears– Sarcomere Shortens– Z Disc– All Sarcomeres Shorten
NEUROMUSCULAR JUNCTION
• Myofiber– Dystrophin– Sarcolemma– Endomesium– Perimesium– Epimesium– Tendon of Insertion
NEUROMUSCULAR JUNCTION
• Remove Threshold Stimulus– Na+1 Gates Close– K+1 Gates Open– Repolarization– Refractory– AChE– Actin-Myosin unlock– Troponin-Tropomyosin Complex unlock
NEUROMUSCULAR JUNCTION
• Remove Threshold Stimulus– H Zone Reappears– Sarcomeres Return – Ca+2 Transported to Organelle of Storage– Calsequestrin– Ca+2 Gates Closed– Expenditure of Energy
MOTOR UNIT
• One Somatic Motor Neuron
• 150 Myofilbers
• Epimesium
• Tendon of Insertion
TWITCH CONTRACTION
• Response to One Stimulus
• Latent Period
• Contraction Period
• Summation Period
• Refractory Period
• Relaxation Period
APPLICATION OF STIMULI
• Treppe
• Complete Tetanic
• Incomplete Tetanic
• Wave Summation– Smooth Summation– Rough Summation
MUSCULAR TONUS
• Partial Contraction
• Involuntary Contraction
TYPES OF MOVEMENTS
• Isotonic– Examples:
• Isometric– Examples:
TYPES OF MUSCLES
• Red Muscles– # Myoglobin– Slow– Examples:
• White Muscles– # Myoglobin– Fast– Examples:
TYPES OF MUSCLES
• Red and White Mixture– # of Myoglobin– Examples: