Figure 1. Images in a 72-year-old woman with epigastric pain. (a) Resected specimen shows multiple tumor nodules in the periphery of the rim(white arrows) and a central area of tumor with necrosis and fibrosis (black arrows). (b) Transverse US image of the spleen shows a solitary mass (5-6 cm) with an echogenic rim (arrow) and a hypoechoic center (arrowhead). Doppler results showed this rim to be hypervascular. (c) Transverse contrast-enhanced early portal venous phase CT scan shows a solitary 6-cm mass with contrast enhancement in the rim (white arrow) and decreased attenuation in the center (arrowhead). Two enhancing masses (black arrows) are seen in the liver.

Figure 2. Images in a 68-year-old woman with several weeks of back pain who was proved at percutaneous biopsy to have metastases in the fourth lumbar vertebral body. (a) Resected specimen shows the tumor has grossly enlarged and completely replaced the spleen. Multiple areas of fibrosis (arrows) and necrosis are present. (b) On transverse contrast-enhanced early portal venous phase CT scan, the massively enlarged spleen (arrows) is completely replaced by tumor. Multiple areas of low attenuation ranging in size from a few millimeters to 3 4 cm are seen throughout the spleen.