S U B J E C T I N D E X

Acetylcholine: gastric output 553 metabolism 553 release inhibited via GABA receptors 565 release from superior cervical ganglion 565 release in CNS 199

Acetylcholinesterase: in hypothyroid rats 23 molecular forms in myotubes 121

Adenosine: receptors 165 uptake in slices 103

Adenosine uptake: characteristics 104 Adrenaline: substrate for MAO 493 Adrenergic drugs: effects on tryptophon hydroxylase

activity 413 Adrenergic receptors: 243 fl-Adrenergic stimulation: causes increase in

noradrenaline synthesis 165 Amines: in vivo release from hippocampus 513 Amino acids: levels in seizure susceptible rats 273 y-Aminobutyric acid: (GABA) 287 Ammonia: effects on enzymes in citric acid cycle 115 Antibodies: to gastrin 34 ATPase: in cholinergic synaptic vesicles 249 Axoplasm: of squid and in RNA 435

Benzodiazepine: receptors in different species Benzodiazepine receptors: photolabelling

experiments 267 Binding: of [3H]glutamate 483

of MPTP to human and animal brain 507 Bombesin: in insect larva 316

267

Caerulein: effect on brain self-stimulation 339 Calcium: uptake by lipids in Synaptosomes 59 [t4C]ct-Aminoisobutyrate: release from cortex slices 207 c-AMP: effect of transmitters on snail heart 349 Cardiac glycoside: binding 451 Catecholamines: co-localised with neuropeptide Y 2

interaction with neuropeptide Y in rat brain 355 relationship with neuropeptide Y and neuroendocrine function 355

Catechol-O-methyltransferase: in rat brain 581 two dimensional gel electrophoresis 581

Cerebellum: isolation of neurones, astroglia and synaptic complexes 179

Chironomus tentans: dipteran insect 311 Cholecystokinin: effect on brain self-stimulation 339 Cholesterol: Synthesis in oligodendrocyte-enriched

cultures 77 Cholinergic: synaptic vesicles 249 Cholinergic neurotoxin: ethylcholine mustard aziridinium

ion 199 Cholinergic vesicles: ATPase associated with sugars 249 Chlorimipramine: effect on 5-HT synthesis 403 Chlorpromazine: effect on dopamine receptors 559 Chromaffin cells: from amphibians 303 Citric acid cycle: 115 Co-existence: of 5-hydroxytryptamine and

substance P 345 of neurotransmitters in Nereis brain neurones 333

Co-localisation: of neuropeptide Y and catecholamines 2 of neuropeptide Y and somatostatin 3

Culture: of glial cells 32 of rat embryo cerebral hemispheres 397

2-Deoxy-D-glucose 553 Diacylglycerol kinase and lipase: activities in rat brain

fractions 213 Dipteran: insect 311 Dopamine-fl-hydroxylase: in RNA 93 Dopamine receptors: different subclasses 559

in bovine caudate nucleus membranes 559 Dynorphin: in Nereis brain 330

fl-Endorphin: In Nereis brain 330 Enkephalin: in insect larva 315

in Amphibian chromaffin cells 303 in Nereis brain 330

Enzyme: of citric acid cycle in brain 116 Epilepsy: Na,K-ATPase transport 456 Estrogen receptors: 587

localization and distribution 587 monoclonal antibodies 587

Ethylcholine mustard aziridinium ion: 199 Exocytosis: of serotonin 144

Fatty acids: synthesis in oligodendrocyte enriched cultures 77

Fenfluramine: effect on 5-HT synthesis 403 Ferret: gastrin-34 in brain 535

GABA: binding in different buffers 223 GABA: regulation and synthesis 287

uptake by lipids in synaptosomes 59 GABA receptors: effect of thiopental 417

in rat brain 417 mediate inhibition of acetylcholine release from

superior cervical ganglion 565 GABA release: effect of nipecotic acid and methionine

sulfoximine 389 influence of glutamine 389

GAD: turnover 289 Gangliosides: regulation of synthesis 501 Gastric acetylcholine: central regulation 553 Gastric acid: output controlled by central

regulation 553 Gastric output: of acetylcholine and acid 553 Gastrin-34: antibodies 535 Glia maturing factor: 31 Glial cells: culture 32

in culture 397 Glioblasts: oligosaccharides 31 Glutamate: receptor 481 Glutamate receptor: related to modulation 481 Glutamine: influences GABA release 389 Glycoproteins: of glioblasts 31 Guanylate cyclase: in enriched fractions from

cerebellum 179

Subject Index

Haloperidol: effect on dopamine receptors 559 Helix: localisation of substance P and 5-HT 345 [3H]GABA release: from cerebral cortex 573

ontogeny in rat cerebral cortex 573 [3H]glutamate: binding to striatal membranes 483 HPLC: of enkephalin-like peptides 306 High-performance liquid chromatography: of S100 541 Hippocampal slices: release of GABA 389 Hippocampus: in vivo and release of amines and amino

acids 513 Histamine: in rabbit retina 53

uptake in hypothalamus and retina 55 [3H]Noradrenaline: release from cortex slices 207 [3H]Pyroglutamic acid: uptake and metabolism in

neurone and glial cells in culture 397 5-Hydroxyindole active acid: role in serotonin

release 146 5-Hydroxytryptamine: in insect larva 313

in Nereis brain 330 synthesis in brain areas 403

5-Hydroxytryptamine synthesis: effect of drugs 403 Hypothyroid rats: neuronal RNA and

acetylcholinesterase 23

Imino acids: in mouse brain peripheral tissues 229 lmmunochemical properties: of tyrosine hydroxylase 423 Immunohistochemistry: of amines and peptides in insect

larva 311 of enkephalin-like peptides 303 of neurophysin and vasopressin 299 of neurotransmitters in Nereis 327 of substance P in retinal vessels 377

lmmunocytochemistry: of protein- carboxymethyltransferase and tyrosine hydroxylase 255

Indoklon: induces seizures 41 Intracranial: self stimulation in rats 339

Lipid: synthesis in digodendrocyte-enriched cultures 67 Lipids: from giant panda and bear brains 188

in synaptosomes 59 of brain 187

Locust: localisation of neurophysin and vasopressin immunoreactivities 299

Long-chain fatty acids: of brain 187

MAG: in central and peripheral nerve through phytogeny 52 I

M A O : oxidation of adrenaline and noradrenaline 493 role in 5-HT neurochemistry 150

MAO-A: Substrate specificities in human brain 496 MAO-B: Substrate specificities in human brain 496 MBP: in central and peripheral nerve through

phytogeny 521 Membrane flow: effect of drugs 501 Methionine sulfoximine: effect upon GABA release 389 Modulation: of transmission via glutamate

receptors 48 l Monoamine oxidase (MAO): two forms in human and

rat brain 493 Monoctonal antibodies: to human estrogen

receptors 587 Morphometric studies: on distribution of neuropeptide Y

and catecholamines 360 MPTP: binding and uptake by brain preparations 507

Muscarinic receptors: heterogeneity of nucleotide modulation 47 involvement in release and synthesis of

nodradrenaline 171 Muscimol: binding in different buffers 223 Muscular myogenesis: 121 Myelin: associated glycoprotein (MAG) 521

basic protein (MBP) 521 glycoprotein and basic protein 521 incorporation of sulfatides 109

Myelin basic protein = see MBP Myelin glycoprotein = see MAG Myotubes: cultured 124

expression of molecular forms of acetylcholinesterase [21

:~-Neoendorphin: in Nereis brain 330 Nere&: localisation of neuropeptides 327 Nerve terminals: from superior cervical ganglion 565 Neuroleptics: effect of neurotensin levels 429 Neurones: in culture 397 Neuropeptides: in Nereis Neuropeptide Y: 1

characterisation t distribution 2 in CNS 14 in peripheral nervous system 4 interactions with catecholamines in rat brain 355 relationship to neuroendocrine function 355 search of a function 9

Neurophysin: in locust embryo 299 Neurotensin: regional telencephalic levels 429

effect of neuroleptics 429 Neurotoxin: of cholinergic nerve terminals 199 Nipecotic acid: effect upon GABA release 389 Nitrobenzylthioinosine: sensitive and insensitive sites for

adenosine uptake 103 Non-vagotomized rats: self stimulation 339 Noradrenaline: release and synthesis 171

substrate for MAO 493 synthesis 165

Nucleotide: modulation of muscarinic receptors 47 Na,K-ATPase: 449

preparations used in biochemical studies 452 involvement in epilepsy 456

Oligodendrocyte: enriched cultures--lipid synthesis: 67 enriched cultures--relationship between pentose-

phosphate pathway and synthesis of lipids 77 role in incorporating sulfatides into myelin 109

Oligosaccharides: in rat glioblasts 31 Ontogeny: of K+ stimulated release of [3H]GABA 573

Pentose-phosphate pathway: In oligodendrocyte enriched glial cultures 77

Pheochromocytomas: isolation of mRNAs 93 Pipecolic acid: 230 Polysomes: and mRNA 381

membrane bound and free 381 Potassium-stimulated: release of [3H]GABA 573 Presynaptic receptors: in serotonin release 157

involvement in serotonin release 146 Proctolin: in insect larva 315 Proenkephalin A: in mRNA 33

xii

Subject Index

Protein-O-carboxylmethyltransferase: localisation in rat brain 255

Protein synthesis: by rat brain polysomes 384 Pyridoxal kinase: in GABA synthesis 289

Quipazine: effect on 5-HT synthesis 403

Radioimmunoassay: of gastrin 537 Radioimmunological: studies on neurophysin and

vasopressin-like peptides 299 Receptors: to glutamate 481

benzodiazepine 267 GABA-A and GABA-B 565 for GABA 417 for neuropeptide Y 3 to estrogen 587

~t-Receptors: 243 effect of reserpine administration 243

Release of 5-HT: role of tryptophan 143 Reserpine: effect of or-receptors Retina: fate and origin of histamine 53 Retinal: gangliosides 501 Retinal pigment epithelium cells (RPE): 527 RPE: culture 527

retinoid-binding proteins 527 retinal esterification 527

Retinal vessels: localisation of substance P 377 Retinoid: binding proteins 527 Retinal esterification: 527 RNA: in hypothyroid rats 23 mRNA: from human pheochromocytomas 93

in squid axoplasm 435 in translation and reverse transcription 381 of dopamine-fl-hydroxylase, tyrosine hydroxylase and

proenkephalin A 93

Seizure: susceptible rats 273 resistant rats--in vivo release of amines and amino acids from the

hippocampus 513 Seizures: induced by indoklon 41

sound-induced 273 Serotonin: 141

a classical neurotransmitter 151 binding to frontal cortex membranes 235 released by exocytosis 144 see 5-hydroxytryptamine (5-HT) release 146 release and metabolism 156

Serotonin binding: effect of bicarbonate 235 Serotonin release: role of 5-hydroxyindoleactic acid 146 Serotonergic neurones: increase in tryphphon-hydroxylase

caused by electric at stimulation 83 Sialoglycoprotein: regulation of Diosynthesis 501 Sodium Potassium ATPase = see Na,K-ATPase

Sodium pump: 477 Sodium valproate: toxicity versus seizures induced by

indoklon 41 treatment of rats 41

Soman intoxication in hypothyroid rats 23 Somatostatin: co-localised with neuropeptide Y 3 Spinal ganglia: diosynthesis of Substance P 547 S100 protein: isolation and chromatography 541 Squid: mRNA in axoplasm 435 Starvation: and imino acids 229 Substance P: biosynthesis in spinal ganglia 547

effect on snail central neurones 347 effect on snail heart 345 immunoreactivity in human retinal vessels 377 high molecular precursor proteins 547 in snail CNS and peripheral tissues 345

Sulfatides: delivery from oligodendroglial and microsomes into myelin 109 effect of undernutrition on incorporation into

myelin 109 Superior cervical ganglion: release of acetylcholine 565 Synaptic vesicles: cholinergic ones associated with

sugars 249 Synaptosomes: activation of noradrenaline release and

synthesis caused by muscarinic receptors 171 from normoxic and ischaemic brain 59 incorporation with [taC]arachidonate 214 noradrenaline synthesis 165

Thiopental: effect on GABA receptors 417 Toxicity: caused by sodium valproate 41 Transcription: in rat brain 381 Translation: in rat brain 381 Tryptophan: role in 5-HT metabolism 155

role in 5-HT release 143 role in serotonin metabolism 142 hydroxylase 83

Tryptophan-hydroxylase: increases by electrical stimulation 83 in midbrain 413 in human brain 423 in insect larva 314 in RNA 93 localisation in rat brain 255 purification and immunochemical properties 423

Tryptophan hydroxylase activity: effect of adrenergic drugs 413

Uptake: of MPTP by human and animal brains 507

Vagotomized rats: self stimulation 339 Vasopressin: in locust embryos 299 Veratoidine: effect on release of radioactive noradrenaline

and ~t-aminoisobutyrate 207

Zotepine: effect on dopamine receptors 559

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