STEPs | CANINE PHENOBARB

Suggested guidelines for canine phenobarbital treatment

Algorithm Canine patient receiving

phenobarbital (e.g. for epilepsy)

Routine check every 6 months*

CBC, Chem, BAST, trough phenobarb levels

(12hrs post pill)

Adjust phenobarb dose accordingly*

Significantly increased Bile Acids >60mmol/l

Bile acids >30 but <60mmol/L

Consider alternative anti-epi-leptic treatments

Consider alternative anti-epileptic treatments

or investigate for additional illnesses

Sick dog

CBC, chem, lytes, BAST. [peak (5hrs post-pill) &

trough phenobarb levels (12hrs post pill) may

be appropriate if animal over sedated or poorly controlled respectively]

Seizures well controlled, CBC, chem and BAST

unremarkable & phenobarb within therapeutic range

Seizures poorly controlled, and/or significant CBC,

Chem or BAST abnormali-ties +/- phenobarb out-with

therapeutic range

Maintain current doseRe-evaluate anti-epileptic

treatment

Continue with phenobarbital and investigate other

reasons for illness

Bile acids <30mmol/l

Applicable – IDEXX Products & Services

Event Suggested Protocol IDEXX Workflow Key: In-Clinic or Ref-Lab Ref-Lab only In-Clinic Only

Diagnosis CBCChemistry profileElectrolytesBile Acid StimPhenobarb

Chemistry Profile:

Electrolytes:

Haematology:

Bile Acid Stim:

Phenobarb:

Monitoring CBCChemistry profileBile Acid StimPhenobarb

Chemistry Profile:

Haematology:

Bile Acid Stim:

Phenobarb:

VetConnect™ PLUS – Client communication suggestions

• Show your client the diagnosis results• Discuss next STEPs• Discuss the requirement to monitor phenobarbital levels (As per Pharmaceutical Data Sheet)

• Use Client Friendly Summary to outline future monitoring requirement · Discuss organ functions Use Notes function to add in details specific to the Pet Use the calendar function to set date for next check-up / monitoring visit

• When monitoring phenobarbital levels use the tabulation of results to communicate to your client: · Changes in stability Changes in dosage Great News! – “your pet is doing great. Continue the good work”

One-Lab. You choose.

STEPs | CANINE PHENOBARB

Suggested guidelines for canine phenobarbital treatment

If you have questions regarding diagnostics or treatment for any of your patients, please contact our Internal Medicine team on 00800 1234 33 99 (option 1, option 2)

© 2014 IDEXX Laboratories, Inc. All rights reserved. 1406050-0614-UKAll ®/TM marks are owned by IDEXX Laboratories, Inc. or its affiliates in the United States and/or other countries.The protocols / information presented in this document are a general overview to help guide the diagnosis and treatment of routine cases. Diagnostic and treatment decisions for an individual animal remain the responsibility of the attending veterinary surgeon and decisions should never be based solely on laboratory results or general literature.