Supplement Figure 1. Incidence of infusion related reactions according to infusion cycle. Infusion related reactions most frequently developed during the first infusion cycle (40.5%) and appeared to decrease with subsequent infusion cycles.

n=230 n=40 n=37 n=16

Supplement Figure 2. Difference in NCI grade of infusion related reactions according to infusion cycle. There was gradual decrement in the percentage of grade 2 or higher infusion related reactions according to increment of infusion cycle (P<0.001).