surgical treatment of malignant tumors of the head of the pancreas and periampullary region

1
Conclusion: Pancreatoduodenectomy with portal vein resection and left renal grafting is a safe procedure without risk of renal failure. During CT a collateral ow through left ovarian vein were observed. The left renal vein is an adequate vessel for grafting because of relatively easy access with a good chance to obtain a vessel of suitable length and vessel diameter. F-100. Three continuous suction drainages to avoid severe pancreatic stula in patients with soft pancreas after pancreaticoduodenectomy Seiji Yamagishi a , Satoshi Mizutani a , Hideyuki Suzuki a , Takayuki Aimoto b , Akira Muraki a , Ryosuke Nakata a , Eiji Uchida c a Institute of Gastroenterology, Nippon Medical School Musashikosugi Hospital, Japan b Kobayashi Hospital, Japan c Department of Surgery, Nippon Medical School, Japan Background: Pancreatic stula (PF) is a possible cause of fatal com- plication. Adequate drainage after pancreaticoduodenectomy (PD) can prevent from increasing severity. Aims: The Aim of this study is to verify practical effectiveness of three continuous suction drainages after PD. Patients & methods: This is a retrospective review of 34 patients who underwent PD for periampullary cancer. The remnant pancreas showed a soft texture in all cases. Reconstruction was undertaken with Child procedure. And duct-to- mucosa anastomosis (sub-total diversion) was used in pan- creaticojejunostomy (PJ). PF was diagnosed according to the International Study Group for Pancreatic Fistula (ISGPF). All patients (n¼34) were divi- ded into 2 groups. Group1 (n¼14) patients having drainage tubes behind the foramen of Winslow and dorsal space of PJ, Group2 (n¼20): patients having an additional tube in caudal space of left lobe of liver. We compared postoperative pancreatic stula (POPF) severity, additional treatment and mortality between these groups. Results: There were no differences in the background of the two groups. Eleven patients developed into PF. Incidence of grade B and C POPF in group1 and 2 was 50% and 19% respectively. Seven of 14 patients in group1 complicated pancreatic stula and 4 patients required ultrasonic- guided percutaneous drainage. Notably, all abscess site spread in caudal space of left lobe of liver. Although 4 patients in group2 developed into PF, they required only anti-biotic drug. Conclusion: Three adequate continuous drainages can prevent POPF after PD from developing into fatal complication. F-101. Surgical treatment of malignant tumors of the head of the pancreas and periampullary region Igor Khomiak, Volodimir Kopchak, Kostyantin Kopchak, Olexandr Duvalko, Andrii Khomiak National institute of surgery and transplantology named after O.O. Shalimov, Department of pancreatic and bile ducts surgery, Ukraine Background: The problem of surgical treatment of malignant tumors of the periampullary region (MTPR) is a key-point in modern pancreatology. Aims: To improve the results of surgical treatment in patients with MTPR by development and implementation of new surgical techniques Patients & methods: We have analyzed the results of 412 pan- creaticoduodenectomies (PD) in patients with periampullary malignancies in the period of 2001-2011 years. In 296 patients standard Whipple pro- cedure was performed, in 116 patients with malignancies of papilla of Vater or distal part of bile duct pylorus-preserving PD was preferred. We per- sonalized our surgical strategy and implemented modern techniques. In 26 patients additional vascular resections were performed. In 30 patients we implemented no-touch PD. Results: Postoperative morbidity was 29,5%, postoperative mortality- 2,7%. Median survival was 24, 38, 72 months in patients with pancreatic cancer, bile duct cancer and cancer of papilla of Vater correspondingly. Affection of the portal/superior mesenteric vein is indication for PD with resection and reconstruction of the vessel. Implementation of the PD with preservation of the gastroduodenal artery and dorsal pancreatic artery made it possible to decrease the rate of postoperative complications to 14,8%. Implementation of the technique of PD with selective ligation of inferior pancreaticoduodenal artery decreased the rate of mean intraoperative blood loss. Implementation of new techniques increased resectability rate on 23,8% and decreased postoperative mortality from 4,9% to 2,7%. Conclusion: Development and implementation of new methods of surgical treatment of MTPR allow to decrease complications rate and improve results of treatment of such a complex category of patients. F-102. Depression in pancreatic cancer Dorota Zielinska a , Marek Durlik b a Central Hospital of the Ministry of Interior in Warsaw, Clinical Department of Gastrointestinal Surgery and Transplantation, Poland b Central Hospital of the Ministry of Interior in Warsaw, Clinical Department of Gastrointestinal Surgery and Transplantation, PAN, Poland Background: The connection between depression and pancreatic cancer has been studied for over 30 years. Patients with depression have less favorable life expectancy and worse quality of life. However it remains unknown whether depression heightens the risk of pancreatic cancer or the cancer evokes depressive symptoms. Aims: The aim of this study was to evaluate the connection between a surgical treatment and an occurrence of depression among patients with pancreatic cancer after a radical treatment. Patients & methods: In the study group were included 17 patients with the diagnosis of pancreatic cancer that underwent the radical surgical treatment (R0 resection). The rst comparison group comprised the 13 patients with pancreatic cancer after the palliative resection. The second comparative group comprised 26 patients operated because of pancreatic tumor with the diagnosis other than pancreatic cancer. Patients were hospitalized in Clinical Department of Gastrointestinal Surgery and Transplantation in the period from 1 July 2010 to 30 June 2011. Every patient was evaluated with the Beck Depression Inventory (BDI) before surgery and 1, 6, 12 months after surgery. Results: Depression incidence rates with BDI before surgery and 1, 6, 12 months after surgery respectively: Experimental group: 53%, 60%, 50%, 43%. 1 comparative group: 54%, 58%, 59%, 63%. 2 comparative group: 45%, 58%, 51%, 50%. Conclusion: Our preliminary data indicate that the surgical treatment decreases the incidence of depressive disorder among patients after the radical surgical treatment. Abstracts / Pancreatology 14 (2014) S1eS129 S116

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Page 1: Surgical treatment of malignant tumors of the head of the pancreas and periampullary region

Abstracts / Pancreatology 14 (2014) S1eS129S116

Conclusion: Pancreatoduodenectomywithportal vein resection and leftrenal grafting is a safe procedure without risk of renal failure. During CT acollateral flow through left ovarian veinwere observed. The left renal vein isan adequate vessel for grafting because of relatively easy access with a goodchance to obtain a vessel of suitable length and vessel diameter.

F-100.

Three continuous suction drainages to avoid severe pancreatic fistulain patients with soft pancreas after pancreaticoduodenectomy

Seiji Yamagishi a, Satoshi Mizutani a, Hideyuki Suzuki a, Takayuki Aimoto b,Akira Muraki a, Ryosuke Nakata a, Eiji Uchida c

a Institute of Gastroenterology, Nippon Medical School MusashikosugiHospital, JapanbKobayashi Hospital, JapancDepartment of Surgery, Nippon Medical School, Japan

Background: Pancreatic fistula (PF) is a possible cause of fatal com-plication. Adequate drainage after pancreaticoduodenectomy (PD) canprevent from increasing severity.

Aims: The Aim of this study is to verify practical effectiveness of threecontinuous suction drainages after PD.

Patients & methods: This is a retrospective review of 34 patients whounderwent PD for periampullary cancer. The remnant pancreas showed asoft texture in all cases.

Reconstruction was undertaken with Child procedure. And duct-to-mucosa anastomosis (sub-total diversion) was used in pan-creaticojejunostomy (PJ). PF was diagnosed according to the InternationalStudy Group for Pancreatic Fistula (ISGPF). All patients (n¼34) were divi-ded into 2 groups. Group1 (n¼14) patients having drainage tubes behindthe foramen of Winslow and dorsal space of PJ, Group2 (n¼20): patientshaving an additional tube in caudal space of left lobe of liver. We comparedpostoperative pancreatic fistula (POPF) severity, additional treatment andmortality between these groups.

Results: There were no differences in the background of the twogroups. Eleven patients developed into PF. Incidence of grade B and C POPFin group1 and 2 was 50% and 19% respectively. Seven of 14 patients ingroup1 complicated pancreatic fistula and 4 patients required ultrasonic-guided percutaneous drainage. Notably, all abscess site spread in caudalspace of left lobe of liver. Although 4 patients in group2 developed into PF,they required only anti-biotic drug.

Conclusion: Three adequate continuous drainages can prevent POPFafter PD from developing into fatal complication.

F-101.

Surgical treatment of malignant tumors of the head of the pancreasand periampullary region

Igor Khomiak, Volodimir Kopchak, Kostyantin Kopchak, OlexandrDuvalko, Andrii Khomiak

National institute of surgery and transplantology named after O.O.Shalimov, Department of pancreatic and bile ducts surgery, Ukraine

Background: The problem of surgical treatment of malignant tumors ofthe periampullary region (MTPR) is a key-point in modern pancreatology.

Aims: To improve the results of surgical treatment in patients withMTPR by development and implementation of new surgical techniques

Patients & methods: We have analyzed the results of 412 pan-creaticoduodenectomies (PD) in patients with periampullary malignanciesin the period of 2001-2011 years. In 296 patients standard Whipple pro-cedurewas performed, in 116 patients with malignancies of papilla of Vateror distal part of bile duct pylorus-preserving PD was preferred. We per-sonalized our surgical strategy and implemented modern techniques. In 26patients additional vascular resections were performed. In 30 patients weimplemented no-touch PD.

Results: Postoperative morbidity was 29,5%, postoperative mortality-2,7%. Median survival was 24, 38, 72 months in patients with pancreaticcancer, bile duct cancer and cancer of papilla of Vater correspondingly.Affection of the portal/superior mesenteric vein is indication for PD withresection and reconstruction of the vessel. Implementation of the PD withpreservation of the gastroduodenal artery and dorsal pancreatic arterymadeit possible to decrease the rate of postoperative complications to 14,8%.Implementation of the technique of PD with selective ligation of inferiorpancreaticoduodenal artery decreased the rate ofmean intraoperative bloodloss. Implementation of new techniques increased resectability rate on 23,8%and decreased postoperative mortality from 4,9% to 2,7%.

Conclusion: Development and implementation of new methods ofsurgical treatment of MTPR allow to decrease complications rate andimprove results of treatment of such a complex category of patients.

F-102.

Depression in pancreatic cancer

Dorota Zielinska a, Marek Durlik b

a Central Hospital of the Ministry of Interior in Warsaw, ClinicalDepartment of Gastrointestinal Surgery and Transplantation, Polandb Central Hospital of the Ministry of Interior in Warsaw, ClinicalDepartment of Gastrointestinal Surgery and Transplantation, PAN,Poland

Background: The connection between depression and pancreaticcancer has been studied for over 30 years. Patients with depression haveless favorable life expectancy and worse quality of life. However it remainsunknown whether depression heightens the risk of pancreatic cancer orthe cancer evokes depressive symptoms.

Aims: The aim of this study was to evaluate the connection between asurgical treatment and an occurrence of depression among patients withpancreatic cancer after a radical treatment.

Patients&methods: In the study groupwere included 17 patients withthe diagnosis of pancreatic cancer that underwent the radical surgicaltreatment (R0 resection). The first comparison group comprised the 13patients with pancreatic cancer after the palliative resection. The secondcomparative group comprised 26 patients operated because of pancreatictumor with the diagnosis other than pancreatic cancer. Patients werehospitalized in Clinical Department of Gastrointestinal Surgery andTransplantation in the period from 1 July 2010 to 30 June 2011. Everypatient was evaluated with the Beck Depression Inventory (BDI) beforesurgery and 1, 6, 12 months after surgery.

Results: Depression incidence rates with BDI before surgery and 1, 6, 12months after surgery respectively:

Experimental group: 53%, 60%, 50%, 43%.1 comparative group: 54%, 58%, 59%, 63%.2 comparative group: 45%, 58%, 51%, 50%.Conclusion: Our preliminary data indicate that the surgical treatment

decreases the incidence of depressive disorder among patients after theradical surgical treatment.