symposia | september 5 (wed), 2018 · susana g. santos，andreia m. silva，josé h. ... ，maria...

40 5th TERMIS World Congress 2018

★：Keynote

Time Room 1 (Main Hall) Room 2 (Annex Hall 1) Room 3 (Annex Hall 2)

Symposia | September 5 (Wed), 2018

03-SY Regenerative therapy in Reconstructive and Aesthetic Plastic SurgeryChairs: Hiroshi Mizuno, Kazuto Hoshi

03-SY-1: “Plastic and Regenerative Surgery”: Historical Review and State-of-the-Art Clinical ScienceHiroshi MizunoDepartment of Plastic and Reconstructive Surgery, Juntendo University, Tokyo, Japan

03-SY-2: A new strategy for the treatment of giant congenital melanocytic nevus using culture epithelial autograft (JACE®) Naoki Morimoto，Toshihito Mitsui，Atsushi Mahara，Natsuko Kakudo，Tetsuji Yamaoka，Kenji KusumotoDepartment of Plastic and Reconstructive Surgery, Kansai Medical University, Japan

03-SY-3: Phase 1 Clinical trial of Autologous Quality and Quantity Cultured vascular and tissue regenerative cell therapy for Chronic Non-Healing Limb UlcerRica Tanaka，Taro Fukuta，Satoshi Fujimura，Kayo Arita，Rie Ito-Hirano，Hiroshi MizunoDepartment of Plastic and Reconstructive Surgery, Juntendo University, Tokyo, Japan

03-SY-4: Impaired wound healing after radiation therapy: Influence of radiation dose fractionation and improvement by stem cell therapyRintaro Asahi，Szu-Hsien Wu，Takako Shirado，Kotaro YoshimuraDepartment of Plastic Surgery, Jichi Medical University, Japan

03-SY-5: Clinical application using autologous cell-engineered chondrocytes transplantation in aesthetic and reconstructive surgeryHiroko Yanaga，Keisuke Imai，Masayuki Miyata，Ken Matsuda，Katsu YanagaYanaga CLinic and Tissue Culture Laboratory, Fukuoka, Japan

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02-SY Regenerative Rehabilitation: the Key to Translating Tissue Engineering and Regenerative TechnologiesChairs: Nick Willett, Akira Ito

02-SY-1: Regenerative Rehabilitation: the key to Translating Tissue Engineering and Regenerative TechnologiesDietmar Werner HutmacherCentre in Regenerative Medicine, Institute of Health and Biomedical Innovation, Queensland, Australia / ARC Training Centre In Additive Biomanufacturing, Queensland University of Technology (QUT), Brisbane, QLD / Institute for Advanced Study, Technische Universität München, Germany

02-SY-2: Principles of Regenerative RehabilitationNick WillettEmory University, USA

02-SY-3: Rehabilitation program after cell therapy for treatment of femoral head osteonecrosis: A narrative review of literature and case seriesTomoki AoyamaHuman Health Sciences, Graduate School of Medicine, Kyoto University, Japan

02-SY-4: Muscle-contraction training showed the potential to maximize the efficacy of cell transplantation treatment for Duchenne Muscular Dystrophy (DMD)Nana Takenaka，Megumi Goto，Rukia Ikeda，Midori Tanaka，Yuta Itoh，Keisuke Kawakami，Hidetoshi SakuraiCenter for iPS Cell Research and Application, Japan

02-SY-5:Rehabilitative Exercise and Spatially Patterned Bioengineered Scaffolds for Treatment of Volumetric Muscle LossKarina Nakayama，Cynthia Alcazar，Marco Quarta，Thomas Rando，Ngan HuangCardiothoracic Surgery, Stanford University, Stanford, CA, United States / Stanford Cardiovascular Institute, Stanford University, Stanford, CA, United States / Veterans Affairs Palo Alto Health Care System, Palo Alto, CA, United States / Neurology and Neurological Sciences, Stanford University, Stanford, CA, United States

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01-SY Disease model for a new drug using an iPSC technologyChairs: Jun Takahashi, Noriyuki Tsumaki

01-SY-1: Application of iPSC technology to disease modeling for chondrodysplasiaNoriyuki TsumakiCenter for iPS Cell Research and Application, Kyoto University, Japan

01-SY-2: Engineering bone-like nodules from human iPS cells as a research platform for bone biologyShunsuke Kawai，Hiroyuki Yoshitomi，Junko Sunaga，Cantas Alev，Sanae Nagata，Megumi Nishio，Masataka Hada，Kenichi Fukiage，Taiji Adachi，Shuichi Matsuda，Junya ToguchidaDepartment of Cell Growth and Differentiation, Center for iPS Cell Research and Application, Kyoto University, Kyoto, Japan / Department of Orthopaedic Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan

01-SY-3: Development of a 3-Dimensional Cell Model to Study Right Heart FailureAida Llucia-Valldeperas，Rowan Smal，Kondababu Kurakula，Peter ten Dijke，Harm-Jan Bogaard，Anton Vonk-Noordegraaf，Marie-Jose Goumans，Frances S de ManDepartment of Pulmonology and Physiology, VU University Medical Center, Amsterdam, The Netherlands

01-SY-4: Maturation and Disease of Human Neuromuscular Connectivity Revealed through OptogeneticsOlaia F Vila，Sebastien G.M. Uzel，Stephen P Ma，Damian Williams，Roger D Kamm，Gordana Vunjak-NovakovicDepartament of Biomedical Engineering, Columbia University, New York, USA

01-SY-5: Stem cell based microphysiological Organ-on-a-Chip systems as in vitro models of human tissue with physiological structure and functionPeter LoskillFraunhofer Institute for Interfacial Engineering and Biotechnology IGB, Stuttgart, Germany / Dept. of Women’s Health, Research Institute for Women’s Health, Faculty of Medicine, Eberhard Karls University Tübingen, Tübingen, Germany

14:20 - 15:50

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★：Keynote

Time Room 4 (A) Room 5 (B-1) Room 6 (B-2)


06-SY Gene therapy for bone regenerationChairs: Fergal J O Brien, Heinz Redl

06-SY-1: Gene2Skin: Scaffold-based delivery of therapeutic genes for enhanced skin repairFergal J O Brien，Rosanne M Raftery，Ashang Luwang Laiva，Michael B KeoghTissue Engineering Research Group, Dept. of Anatomy, Royal College of Surgeons in Ireland (RCSI), Ireland / Advanced Materials and Biomedical Engineering Research (AMBER) Centre, RCSI, Ireland / Trinity Centre for Bioengineering, Trinity College Dublin, Ireland

06-SY-2: Combinatorial gene therapy for bone regenerationAra Hacobian，Amelie Frischer，Katja Posa-Markaryan，Teresa Brenner，Heinz RedlLudwig Boltzmann Institute for Experimental and Clinical Traumatology, Austria

06-SY-3: Gene-activated matrices (GAMs) – Concept, limitations and future developmentsGeorg A FeichtingerDivision of Oral Biology, School of Dentistry, Faculty of Medicine and Health, University of Leeds, UK

06-SY-4: RANKL-induced M1-like macrophages are actively involved in bone formationLan Xiao，Rong Huang，Xin Wang，Yin Xiao, Yinghong Zhou, Shengfang WangThe Institute of Health and Biomedical Innovation, Queensland University of Technology, Australia

06-SY-5: Collagen type X plays an important role in mesenchymal stem cell mediated cartilage formation and subsequent endochondral ossificationEric Farrell，Callie Knuth，Enrique Andres Sastre，Niamh B Fahy，Janneke Witte Bouma，Jeroen van de Peppel，Maarten Koudstaal，Eppo WolviusErasmus MC, Rotterdam, The Netherlands

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05-SY Regenerative medicine in ophthalmological fieldChairs: Kohji Nishida, To be announced

05-SY-1: Transplantation of cultivated oral and corneal epithelial cell sheet Yoshinori OieDepartment of Ophthalmology, Osaka University, Osaka, Japan

05-SY-2: Anti-Inflammatory Properties of Corneal Stroma-Derived Stem Cells: Potential as a Topical Therapy for the Ocular SurfaceOwen Mclntosh，M. Lizeth Orozco Morales，Nagi M Marsit，Andrew Hopkinson，Laura E SidneyAcademic Ophthalmology, Division of Clinical Neuroscience, University of Nottingham, Nottingham, UK

05-SY-3: Advanced in vitro three-dimensional cornea tissue modelChiara Ghezzi，Tina B McKay，Siran Wang，James L Funderburgh，David L KaplanDepartment of Biomedical Engineering, Tufts University, Medford, USA

05-SY-4: Strategy for mass production of corneal endothelial substitute cells from iPS cellsShin HatouDevelopment of Ophthalmology, Keio University School of Medicine, Japan

05-SY-5: Organotypic Culture of Adult Porcine Neuroretina: High-Throughput Assessment of Retina Explant Viability, Morphological Alterations, and Retinal Morphometric AnalysisChristina Lee Rettinger，Heuy-Ching Hetty WangOcular and Sensory Trauma, US Army Institute of Surgical Research, USA

05-SY-6: Genetically engineered iPSC-retina for improved retinal reconstruction after transplantationTake Matsuyama，Hung-Ya Tu，Jianan Sun，Tomoyo Hashiguchi，Junki Sho，Genshiro A Sunagawa，Momo Fujii，Akishi Onishi，Masayo Takahashi，Michiko MandaiCenter for Developmental Biology, RIKEN, Japan

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04-SY Advances in cell encapsulation technologies for regenerative medicine Chairs: Omid Veiseh, Mark Chong

04-SY-1: Cell Encapsulation - A New Modality For Long-Term CuresDevyn SmithSigilon Therapeutics, USA

04-SY-2: Encapsulated cell therapies for diabetesOmid VeisehDepartment of Bioengineering, Rice University, Houston, TX / Sigilon Therapeutics, Cambridge, USA

04-SY-3: To be announcedJaime GiraldoJDRF, USA

04-SY-4: Preventing Hypoxia-induced Beta Cell Death and Dysfunction via Oxygen-generating MicrobeadsJia-Pu Liang，Maria Coronel，Minh Dang，Cherie StablerDepartment of Biomedical Engineering, University of Florida, Gainesville, FL, USA

04-SY-5: Engineering 3D Islet Micro ChipJia-Pu Liang，Kaiyuan Jiang，Smit Patel，Cherie Stabler, Deborah ChaimovDepartment of Biomedical Engineering, University of Florida, Gainesville, USA

14:20 - 15:50

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Symposia | September 5 (Wed), 2018Time Room 7 (D) Room 8 (E) Room 9 (C-2)

★：Keynote

08-SY Induction and modulation of immune response for tissue regeneration Chairs: Bizios Rena, Julia Babensee

08-SY-1: Lessons from Translation: Engineering a pro-regenerative immune environment with biomaterialsJennifer H ElisseeffOphthalmology, Johns Hopkins University, Baltimore, MD, USA

08-SY-2: Exosome-loaded electrospun fibers: design of tissue scaffolds towards regenerative immunomodulationNi Su，Ying Luo，Yaoyao HaoDepartment of Biomedical Engineering, College of Engineering, Peking University, Beijing, China

08-SY-3: Immune-instructive materials for tissue regeneration and healing Amir M GhaemmaghamiUniversity of Nottingham, UK

08-SY-4: Novel Engineered Growth Factor Enhances Pro-Regenerative T Cell Mobilization and FunctionJacqueline A Larouche，Ziad Julier，Anthony J Park，Mikaël M MartinoAustralian Regenerative Medicine, Monash University, Melbourne, Australia / Department of Biomedical Engineering, University of Michigan, Ann Arbor, USA

08-SY-5: Extracellular Vesicles in Tissue Repair and Regeneration: The Contribution of Immune CellsSusana G. Santos，Andreia M. Silva，José H. Teixeira，Maria I. Almeida，Mário A. BarbosaINEB - Instituto de Engenharia Biomedica, i3S - Instituto de Investigacao e inovacao em Saude da Universidade do Porto, Portugal

08-SY-6: Immunomodulation Strategies Using BiomaterialsJulia E. Babensee，Wallace, H. CoulterDepartment of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA, USA

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07-SY The interactions of biomaterials and stem cells/tissue regenerationChairs: Chengtie Wu, Jiang Chang

07-SY-1: Regulation of stem cell fate using bioactive ions for tissue engineeringJiang Chang，Chengtie WuShanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai, China

07-SY-2: Molecular Mechanisms of Bioactive Glass -Induced Cell Adhesion and Osteogenic Differentiation in Human Adipose Stem CellsLaura Hyvaeri，Miina Ojansivu，Xiaoju Wang，Minna Kellomäki，Leena Hupa，Sari Vanhatupa，Susanna MiettinenAdult Stem Cell Research Group, Faculty of Medicine and Life Sciences and BioMediTech Institute, University of Tampere, Tampere, Finland.

07-SY-3: 3D-Printing of multifunctional scaffolds for bone therapy and regenerationChengtie WuShanghai Institute of Ceramics, Chinese Academy of Sciences, China

07-SY-4: Directed Cellular Activities Based on Vapor-Deposited Polymers Hsien-Yeh ChenDepartment of Chemical Engineering, National Taiwan University, Taipei, Taiwan

07-SY-5: Development of sprayable colloidal wound dressing for digestive system cancer therapyAkihiro Nishiguchi，Tetsushi TaguchiBiomaterials Field, Research Center for Functional Materials, National Institute for Materials Science, Ibaraki, Japan

07-SY-6: Effect of biomimetic and protein repulsive surfaces for human pluripotent stem cells cultivationVladimir Proks，Josef Jaroš，Ilya Kotelnikov，Josef Lavický，Jakub Pospíšil，Aleš HamplDepartment of Biomaterials and Bioanalogous Systems Institute of Macromolecular Chemistry Academy of Sciences of the Czech Republic, v.v.i, Heyrovskeho nam. 2, Prague 6 Czech Republic

07-SY-7: Biomaterial-driven vascularisation: strategies for developing vascularised cardiac patches Jelena Rnjak-Kovacina，Fengying Tang，Kieran Lau，Xiaoting Lin，John M Whitelock，Megan S LordGraduate School of Biomedical Engineering, UNSW Sydney, Sydney, Australia

14:20 - 15:50

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09-SY Biomaterials and Additive Manufacturing for early intervention of osteoarthritis (H2020-MSCA-RISE BAMOS project)Chairs: J. Miguel Oliveira, Chaozong Liu

09-SY-1: Natural-based Polymers and Bioinks in Bioprinting and Tissue RegenerationJ. Miguel Oliveira，Rui L. Reis3B's Research Group, Univ Minho, Portugal

09-SY-2: Subchondral bone remodelling in osteoarthritic jointsChaozong Liu，Jing Niu，Sammy Shenmao Chen，Maryam TamaddonUniversity College London, UK

09-SY-3: Optimization methodology for the material assignation of bioprinted scaffolds based on genetic algorithms and finite element analysis Rubén Paz Hernández，Noelia Diaz，Ricardo Donate，Chaozong Liu，Rubén Paz，Sara Ajami，Zaida OrtegaDepartamento de Ingeniería Mecánica.Universidad de Las Palmas de Gran Canaria. Las Palmas GC. Spain

09-SY-4: 3D Bioprinting:opportunities and changes Bin ZhangZhejiang University, China

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★：Keynote



13-SY Potential of polydactyly-derived cells for regenerative medicineChairs: Masato Sato, Setsuko Hashimoto

13-SY-1: Clinical study of regenerative therapy for osteoarthritis of the knee using allogeneic chondrocyte sheetsMasato Sato，Miki Maehara，Takumi Takahashi，Eriko Toyoda，Eri Okada，Ayako Watanabe，Naoki Takatori，Takehiko Takagi，Tadashi Akamatsu，Shokyu Gen，Kazuaki Matsumura，Hiroshi Nagashima，Masahiko WatanabeDepartment of Orthopaedic Surgery, Tokai University School of Medicine, Japan

13-SY-2: Developing the systematic scale-out production of cells for cell therapiesTohru Sugawara，Tomoyuki Kawasaki，Yuzuru Ito，Masakatsu Takeuchi，Shigehiro Yoshimura，Masato Sato，Hidenori AkutsuNational Center for Child Health and Development，Center for Regenerative Medicine, Tokyo, Japan

13-SY-3: The new platform for the evaluation of regenerative productRyo Matoba，Noriko Ito，Fumi Takada，Hiroshi Iijima，Hidenori Akutsu，Eriko Toyoda，Masato SatoDNA Chip Research Inc., Tokyo, Japan

13-SY-4: Global Business Development of Cell Sheet EngineeringSetsuko HashimotoCellSeed Inc., Japan

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12-SY Advances in Scaffold-Free, Cell Spheroids-Based Tissue EngineeringChairs: Nicanor I. Moldovan, Koichi Nakayama

12-SY-1: Translational research of scaffold free tubular tissue modeled with Kenzan method Bio-3D Printer for cardiovascular surgeryManabu ItohDepartment of Thoracic and Cardiovascular Surgery, Saga Medical School, Japan

12-SY-2: The Efficacy of a Scaffold-free Bio 3D Conduit on Peripheral Nerve RegenerationTomoki AoyamaHuman Health Sciences, Graduate School of Medicine, Kyoto University, Japan

12-SY-3: Artificial trachea and esophagus using bio 3D printerKeitaro Matsumoto，Daisuke Taniguchi，Yosuke Takeoka，Ryusuke Machino，Yasuaki Taura，Katsunori Takagi，Shosaburo Oyama，Tomoyuki Tetsuo，Masaaki Moriyama，Naoto Matsuo，Masaki Kunizaki，Shigekazu Hidaka，Tomoshi Tsuchiya，Koichi Nakayama，Takeshi NagayasuDepartment of Surgical Oncology, Nagasaki University, Nagasaki, Japan / Medical-engineering hybrid professional development program, Nagasaki University, Nagasaki, Japan

12-SY-4: Creation of functional 3D tissue for regenerative medicine and drug developmentShizuka Akieda，Yoshihiro KunitomiCyfuse Biomedical K.K., Tokyo, Japan

12-SY-5: 3D Bioprinting of Regenerative Medicine and Tissue Engineered Products: U.S. Regulatory PerspectiveLaura RiclesUnited States Food and Drug Administration, USA

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11-SY Public-private partnership for research on standardization and validation of methods for tumorigenicity assessment of regenerative medical products (MEASURE)Chairs: Yoji Sato, Hiroto Bando

11-SY-1: MEASURE: Public-Private Partnership Initiative in Japan for Research on Standardization and Validation of Methods for Tumorigenicity Assessment of Regenerative Medical ProductsYoji SatoDivision of Cell-Based Therapeutic Products, National Institute of Health Sciences, Kawasaki, Japan

11-SY-2: In vitro assays for detection of residual undifferentiated iPS cellsAkihiko Azuma，Takeshi WatanabeFUJIFILM Corporation, Japan

11-SY-3: In vitro assays for detection of transformed cellsNorihiko Shiraishi，Kiyoko BandoR&D Planning Department, R&D Division, Kyowa Hakko Kirin Co., Ltd., Japan

11-SY-4: In vivo assays for detection of residual undifferentiated iPS cellsNaoko TanakaEvaluation Center, TERUMO CORPORATION, Japan

11-SY-5: Evaluation of a method for biodistribution of cell therapy productsYoichi NaritomiAstellas Pharma Inc., Ibaraki, Japan

15:50 - 17:20

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★：Keynote



16-SY Gene Delivery in Tissue EngineeringChairs: Wenxin Wang, Dezhong Zhou

16-SY-1: Highly branched poly(beta-amino ester) for gene therapy of Recessive Dystrophic Epidermolysis Bullosa (RDEB)Wenxin Wang，Dezhong Zhou，Lara Cutlar，Irene Lara-Sáez，Ahmed AiedCharles Institute of Dermatology, University College Dublin, Ireland

16-SY-2: mRNA-based therapy for cartilage degeneration diseasesKeiji Itaka，Shinsuke Ohba，Satoshi Uchida，Ung-il Chung，Kazunori KataokaInstitute of Biomaterial and Bioengineering, Tokyo Medical and Dental University, Japan

16-SY-3: Chemically Diverse, Degradable Polymeric Carriers for Nebulized Delivery of Messenger RNA to the LungAsha Kumari Patel，James C Kaczmarek，Kevin K Kauffman，Robert Langer，Daniel G AndersonKoch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA / Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.

16-SY-4: Highly Branched Poly(b-Amino Ester)s as New Gene Delivery VectorsDezhong Zhou，Wenxin WangCharles Institute of Dermatology, University College Dublin, Ireland

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15-SY ISBF-TERMIS Joint Young Scientist Chapters. Biofabrication in TERMChairs: Riccardo Levato, Andres Sanz Garcia

15-SY-1: Bioprinting: the State of the ArtGabor ForgacsUniversity of Missouri, Columbia Missouri and Modern Meadow, Inc. New York, USA

15-SY-2: 3D bioprinting of human hepatic tissue using human liver extracellular matrix as tissue-specific bioinkLuca Frenguelli，ZhenZhen Zhang，Louai Chikh，Walid Al-Akkad，Krista Rombouts，Erik Gatenholm，Massimo Pinzani，Hector Martinez，Giuseppe MazzaUniversity College of London (UCL), Institute for Liver and Digestive Health, London, UK / Engitix Ltd. Royal Free Hospital, London, UK

15-SY-3: Microfluidic bioprinter for in situ patterning of engineered skin graftsRichard Cheng，Gertraud Eylert，Sijin He，Jean-Michel Gariepy，Marc Jeschke，Axel GuentherInstitute of Biomaterials & Biomedical Engineering, University of Toronto, Toronto, Canada

15-SY-4: Spontaneous hair follicle germ (HFG) formation for regenerative medicineChisa Yoshimura，Tatsuto Kageyama，Ken Kataoka，Matteo Moretti，Simone Bersini，Giovanni Velotta，Keiichiro Kasai，Junji FukudaGraduate School of Engineering, Yokohama National University, Yokohama, Japan

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14-SY Recent achievements and future perspective of micro-physiological cell culture systems toward in vitro physiologyChairs: Eric Leclerc, Yasuyuki Sakai

14-SY-1: Applying “Body-on-a-Chip” Systems to Drug DevelopmentMichael L. ShulerMeinig School of Biomedical Engineering, Cornell University, Ithaca, NY, USA

14-SY-2: Organ-on-a-Chip models for drug safety testing and disease modellingPaul VultoMIMETAS, The Netherlands / Academic Centre for Drug Research, Leiden University, The Netherlands

14-SY-3: Parallelized biochips for toxicology studies : the benefit of the collaboration with a clinical teamCécile Legallais，Rachid Jellali，Jean-Charles Duclos-Vallee，Eric LeclercUMR CNRS Biomechanics & Bioengineering, University of Technology; Compiegne, France

14-SY-4: A perfused 3D artificial lymph nodeOyvind Halaas，Andrea Brendolan，Marta Tunesi，Luca Izzo，Manuela Teresa RaimondiDepartment of Clinical and Molecular Medicine, The Norwegian University of Science and Technology, NTNU, Trondheim, Norway / Department of Chemistry, Materials and Chemical Engineering «G. Natta», Politecnico di Milano, Milano, Italy

14-SY-5: Investigation of human induced pluripotent stem cells differentiation in liver biochipEric Leclerc，Mathieu Danoy，Marie Shinohara，Yannick Tauran，Yasuyuki SakaiCNRS, France

15:50 - 17:20

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★：Keynote


19-SY Quantitative X-ray Micro-CT Imaging for Tissue EngineeringChairs: Sarah Cartmell, Shelley Rawson

19-SY-1: Emerging Techniques for Soft Tissue X-ray Micro-CT ImagingShelley Rawson，Graham Coutts，Rob Bradley，Lucy Walton，Catherine Disney，James O'Sullivan，Lauren Scott，Tim L Burnett，Michael J Sherratt，Stuart Allan，Laura Parkes，Sarah H Cartmell，Philip J WithersSchool of Materials, Faculty of Science and Engineering, The University of Manchester, Manchester, UK

19-SY-2: Novel CT imaging techniques for soft tissuesSarah CartmellSchool of Materials, The University of Manchester, UK

19-SY-3: Micro-computed tomography as a tool to improve in vitro bone tissue engineering culturesSandra HofmannOrthopaedic Biomechanics, Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, The Netherlands / Institute for Complex Molecular Systems, Eindhoven University of Technology, Eindhoven, The Netherlands

19-SY-4: Micro-Tomography as a Quality Control Tool for Regenerative MedicineAraida Hidalgo-Bastida，Marta C Catoira，Francesca Boccafoschi，Sarah CartmellSchool of Healthcare Science, Manchester Metropolitan University, Manchester, UK

19-SY-5: 3D X-ray Microscopy: High Resolution Tomographic Technology for Biological SpecimensPhillipp Bastians，Rosy Manser，Ruth RedwanCarl Zeiss Microscopy, Singapore / Carl Zeiss Ltd., Zeiss Group, Cambridge, UK / Carl Zeiss Microscopy, Asia Pacific, Singapore

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18-SY Frontier of research on interstitial cells / extracellular matrix for generating functional tissue and organsChairs: Katsuhisa Matsuura, Kiyotoshi Sekiguchi

18-SY-1: Identification of the tissue specific phenotypes of heart-derived fibroblasts for tissue engineering and further understanding “Heart”Katsuhisa MatsuuraInstitute of Advanced Biomedical Engineering and Science, Tokyo Women's Medical University, Tokyo, Japan / Department of Cardiology, Tokyo Women's Medical University, Tokyo, Japan

18-SY-2: Designer culture substrates based on laminin E8 fragments for robust expansion and differentiation of human pluripotent stem cellsKiyotoshi SekiguchiInstitute for Protein Research, Osaka University, Suita, Japan

18-SY-3: Investigating Cancer Invasiveness and Vasculature with a Biomimetic 3D Model and Patient-Specific Cancer Associated FibroblastsJudith Pape，Mark Emberton，Umber CheemaDivision of Surgery and Interventional Science, University College London, London, UK

18-SY-4: A combined approach to investigate ECM nanostructure remodelling in heart failureAna Rubina Perestrelo，Jorge Oliver de la Cruz，Guido Caluori，Fabiana Martino，Vladimír Vinarský，Ana Catarina Silva，Víta Žampachová，Vladimír Horváth，Petr Skládal ，Stefania Pagliari，Diana S. Nascimento，Perpétua Pinto-do-Ó，Giancarlo ForteInternational Clinical Research Center (ICRC), St. Anne's University Hospital Brno (FNUSA), Brno, Czech Republic

18-SY-5: Organ-Specific Decellularized Extracellular Matrices from PigsEiji Kobayashi，Shin EnosawaDepartment of Organ Fabrication, Keio University School of Medicine, Tokyo, Japan

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17-SY CLAY MATERIALS FOR HARD AND SOFT TISSUE ENGINEERING: from Bench to Clinical translationChairs: Richard OC Oreffo, Jonathan I Dawson

17-SY-1: 2D Nanoclays for Regenerative Medicine, Therapeutic Delivery and Bioprinting Akhilesh K GaharwarDepartment of Biomedical Engineering, Texas A&M University, College Station, TX, USA

17-SY-2: Nanoclay gels for the delivery of regenerative microenvironmentsJonathan I DawsonCentre for Human Development, Stem Cells and Regeneration, University of Southampton, Southampton, UK

17-SY-3: Bisphosphonate-functionalised hyaluronan hydrogel by addition of Laponite clay nanoparticles enhances a sustained release of bone morphogenetic protein-2Yang-Hee Kim，Dmitri Ossipov，Richard O.C Oreffo，Jonathan I. DawsonBone and Joint Research Group, Centre for Human Development, Stem Cells & Regeneration, Institute of Developmental Sciences, University of Southampton, Southampton, UK

17-SY-4: Analysis of material-tissue interactions and degradation for baghdadite scaffolds implanted in large segmental bone defects in sheep tibiaJiao Jiao Li，Colin Dunstan，Austin Akey，David Bell，Martin Vielreicher，Oliver Friedrich，Hala ZreiqatBiomaterials and Tissue Engineering Research Unit, School of Aerospace, Mechanical and Mechatronic Engineering, University of Sydney, Sydney, NSW, Australia / Raymond Purves Bone and Joint Research Laboratories, Institute of Bone and Joint Research, Kolling Institute, Northern Sydney Local Health District, Sydney Medical School Northern, University of Sydney, St Leonards, NSW, Australia

15:50 - 17:20

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★：Keynote

23-SY Tissue engineering and regenerative medicine for joint preservationChairs: Ryosuke Kuroda, Norimasa Nakamura

23-SY-1: Clinical Outcomes of Knee Osteoarthritis Treated With an Autologous Protein Solution InjectionElizaveta KonHumanitas Research Hospital, Italy

23-SY-2: Osteochondral restoration by a biphasic tissue engineered approach for early osteoarthritisNorimasa NakamuraInstitute for Medical Science in Sports, Osaka Health Science University / Global center for medical engineering and informatics, Osaka University, Japan

23-SY-3: Transplantation of synovial mesenchymal stem cells onto repaired meniscus with degenerative tearIchiro SekiyaDirector, Center for Stem Cell and Regenerative Medicine Tokyo Medical and Dental University (TMDU) 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8510, Japan

23-SY-4: Contract Manufacturing of Adipose Derived Mesenchymal Stem Cells for Patients with OsteoarthritisHideto Kaneshima，Masato TsumamotoCellsource Co., Ltd., Tokyo, Japan

23-SY-5: Second-generation cell-based therapies in the continuum of knee careJennifer Woodell-MayBiomet Biologics, Zimmer Biomet, Warsaw, Indiana, USA

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22-SY Biofabrication: from new technologies to clinical applicationsChairs: Lorenzo Moroni, Makoto Nakamura

22-SY-1: The KenZan method: from bench to bedsideKoichi Nakayama Department of Regenerative Medicine and Biomedical Engineering, Faculty of Medicine, Saga University, Japan

22-SY-2: Lithography-based 3D Printing at subcellular resolution and it’s perspectives for TERMAleksandr OvsianikovInstitute of Materials Science and Technology, TU Wien (Technische Universitaet Wien), Getreidemarkt 9, Vienna, Austria

22-SY-3: Lab-on-a-PrinterTM- a 3D Bioprinting Platform Suitable for Phenotypic Analysis of Drug Response in Multiple TissuesSimon Beyer，Katherine Thain，Sheng Pan，Christpher Dickman，Tamer Mohamed，Sam J WadsworthAspect Biosystems, Canada

22-SY-4: Sorting Extracellular vesicles and rare cells from bloodUtkan DemirciStanford University School of Medicine, Department of Radiology / Canary Center at Stanford for Cancer Early Detection / Stanford, USA

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21-SY Tissue Engineering and Regenerative Medicine of the Cornea: Towards a clinical reality through the cooperation of Industry, Government and AcademiaChairs: Miguel Gonzalez-Andrades, May Griffith

21-SY-1: Advanced Therapies for Corneal Endothelial DysfunctionShigeru KinoshitaDepartment of Frontier Medical Science and Technology for Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan

21-SY-2: iPS cell-based treatmentsShigeto ShimmuraDepartment of Ophthalmology, Keio University School of Medicine, Japan

21-SY-3: Design criteria for biodegradable synthetic corneaJons Gunnar Hilborn，May Griffith，Ayan SamantaDepartment of Chemistry-Angstrom Laboratory, University of Uppsala, Sweden / Department of Bioengineering, University of Tokyo, Japan

21-SY-4: Cell-free scaffolds promoting endogenous corneal regenerationMay Griffith，Oleksiy Buznyk，Bruce Allan，Jaganmohan R Jangamreddy，Jagadesh Reddy，M. Mirazul Islam，Philip Lewis，Keith M Meek，Virender S SangwanMaisonneuve-Rosemont Hospital, Montreal, Canada / Dept. of Ophthalmology, University of Montreal, Montreal, Canada / LV Prasad Eye Institute, Hyderabad, India

21-SY-5: Natural-based Approaches to Corneal Tissue Engineering: Fibrin-Agarose Scaffolds and Decellularized XenograftsMiguel Gonzalez-Andrades，Carmen Gonzalez-Gallardo，Miguel Alaminos，Natividad Cuende，M Mirazul Islam，Roholah Sharifi，Claes H DohlmanSchepens Eye Research Institute and Massachusetts Eye and Ear, Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts, USA.

21-SY-6: Limbal Epithelial Stem Cells from bench to bedside: Successes, Hurdles and Future in Cultivated Limbal Epithelial Stem CellMichel Haagdorens，Eline Melsbach，Josephine Behaegel，Carina Koppen，Nadia Zakaria，Sorcha Ni Dhubhghaill，Marie-José TassignonDepartment of Ophthalmology, University of Antwerp, Antwerp, Belgium / Department of Ophthalmology, Antwerp University Hospital, Antwerp, Belgium

17:50 - 19:20

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★：Keynote



26-SY Dental pulp regeneration: How can we reach the goal?Chairs: Satoshi Imazato, Takuya Matsumoto

26-SY-1: Vasculogenic differentiation of dental pulp stem cells in tissue engineeringJacques E. Nor，Zhaocheng Zhang，Jun-Ichi SasakiDepartment of Cariology, Restorative Sciences and Endodontics; University of Michigan, Ann Arbor, Michigan, USA / Department of Biomaterials Science; Osaka University, Osaka, Japan

26-SY-2: Pulpal healing mechanism after exogenous tooth injuries and prospects for regenerative medicine in dentistryHayato OhshimaDivision of Anatomy and Cell Biology of the Hard Tissue, Department of Tissue Regeneration and Reconstruction, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan

26-SY-3: New approach for pulp regeneration by transplantation of scaffold-free 3D constructs of human dental pulp stem cellsJun-ichi Sasaki，Satoshi ImazatoOsaka University Graduate School of Dentistry, Department of Biomaterials Science, Japan

26-SY-4: Application of Bioactive Glass for Regenerative Medicine of Dentin-Pulp ComplexAyako Washio，Takahiko Morotomi，Yasuhiko Tabata，Chiaki KitamuraDivision of Endodontics and Restorative Dentistry, Department of Oral Functions, Kyushu Dental University, Kitakyushu, Japan

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25-SY Extracellular Vesicles in Tissue RegenerationChairs: Wojciech Chrzanowski, Chwee Teck Lim

25-SY-1: Microfluidic Technologies for Exosome and Microvesicle IsolationChwee Teck Lim，Joo Chuan Yeo，Pan ZhangDepartment of Biomedical Engineering, National University of Singapore, Singapore

25-SY-2: Sorting Extracellular vesicles and rare cells from bloodUtkan DemiriciStanford University School of Medicine, Department of Radiology / Canary Center at Stanford for Cancer Early Detection / Stanford, USA

25-SY-3: MSC exosomes and small EVs: extrapolating from cargo to possible mechanisms of actionSai Kiang LimInstitute of Medical Biology, A*STAR, Singapore

25-SY-4: Osteoblast-derived extracellular vesicles as sites of mineral nucleation: application for tissue regenerationOwen Gareth Davis，Sophie C Cox，Richard L Williams，Adam McGuinness，Ioannis Azoidis，Mark P Lewis，Liam M GroverLoughborough University, UK / University of Birmingham, UK

25-SY-5: HYALURONAN-COATED EXTRACELLULAR VESICLES – POTENTIAL TOOLS FOR TISSUE REPAIRKirsi RillaUniversity of Eastern Finland, Finland

25-SY-6: MSC Exosome as a Cell-Free Therapy for Cartilage RepairWei Seong Toh，Sai Kiang Lim，James Hoi Po HuiFaculty of Dentistry, National University of Singapore, Singapore / Tissue Engineering Program, Life Sciences Institute, National University of Singapore, Singapore

25-SY-7: On the Potential of Paracrine Signals for Advanced TherapiesNuno Neves3B’s Research Group - Biomaterials, Biodegradables and Biomimetics, University of Minho, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, Guimarães, Portugal / ICVS/3B’s, PT Government Associate Laboratory, Braga/Guimarães, Portugal / The Discoveries Centre for Regenerative and Precision Medicine, Headquarters at University of Minho, Guimarães, Portugal

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24-SY Vascularization in Tissue & Organ EngineeringChairs: Tatsuya Shimizu, Milica Radisic

24-SY-1: ① VEGF- and PDGF-BB-Decorated Fibrin Matrices ensure Persistent and Therapeutic Vascular Growth ② Biological considerations for therapeutic vascularization in regenerative medicine①Andrea Banfi，Veronica Sacchi，Rainer Mittermayr，Joachim Hartinger，Patrick Heimel，Mikaël M. Martino，Roberto Gianni-Barrera，Jeffrey A. Hubbell，Heinz Redl ②Andrea Banfi①Departments of Biomedicine and of Surgery, Basel University Hospital, Basel, Switzerland ②Department of Biomedicine, Basel University Hospital, Basel, Switzerland

24-SY-2: Microfabricated tissues for medical discovery and therapyMilica RadisicMcMaster University, Canada

24-SY-3: Engineering a Three-dimensional Tissue Using a Perfusable Vascular Collagen-based BedKatsuhisa Sakaguchi，Yusuke Tobe，Tatsuya Shimizu，Mitsuo UmezuSchool of Science and Engineering, Waseda University, Tokyo, Japan

24-SY-4: Vascularized Tissue Engineering Using the Arteriovenous Loop – The Path from the Small Animal Model to the Preclinical Large Animal ModelAnnika Weigand，Justus P. Beier，Rafael Schmid，Jan W. Robering，Aijia Cai，Andreas Arkudas，Raymund E. Horch，Anja M. BoosDepartment of Plastic and Hand Surgery, Laboratory for Tissue Engineering and Regenerative Medicine, University Hospital of Erlangen, Friedrich-Alexander University of Erlangen-Nürnberg (FAU), Germany

24-SY-5: Non-Invasive and Real-Time Measurement of Microvascular Permeability in Intact LungsAlexander James Engler，Andrew V. Le，Micha Sam B. Raredon，Yifan Yuan，Pavlina Baevova，Laura E. NiklasonDepartment of Biomedical Engineering, Yale University, New Haven, CT, USA

17:50 - 19:20

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★：Keynote


29-SY Computational Modeling Stem Cell FateChairs: Kara McCloskey, Masayuki Yamato

29-SY-1: Heterotypic Effects within Cardiac Microtissue Environments on Human iPS-derived Cardiomyocyte Phenotype and FunctionTodd C McDevitt，Tracy A Hookway，Oriane B Matthys，Diwakar Turaga，Ana C SilvaGladstone Institutes / UCSF, USA

29-SY-2: Design of a 3D Organotypic Model to Study Monocyte Extravasation to the Osteoarthritic Joint using a Combined Computational/Experimental ApproachSilvia Lopa，Carlotta Mondadori，Roberta Visone，Alberto Redaelli，Marco Rasponi，Matteo MorettiCell and Tissue Engineering Laboratory, IRCCS Galeazzi Orthopaedic Institute, Italy

29-SY-3: Cell Spheroids as Building Blocks for Scaffold-free BiofabricationNicanor I. MoldovanDepartment of Biomedical Engineering, Indiana University-Purdue University Indianapolis (IUPUI), IN, USA

29-SY-4: Stochastic spatial and temporal population-based model for the co-emergence of vascular patternsKara E. McCloskey，Jose Zamora，Ajay GopinathanGraduate Program in Biological Engineering and Small-scale Technologies (BEST), University of California Merced, USA / School of Natural Sciences, University of California Merced, USA

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28-SY TERMIS-WC Business Plan Competition FinalsChairs: Oliver M Ball, Suzanne Tabbaa

28-SY-1: BiomimX: Beating organs on chip advancing drug screeningPaolo Occhetta，Stefano Ugolini，Roberta VisonePolitecnico di Milano, Italy

28-SY-2: BIOreACT: Making drug and cosmetic testing realisticRaphael CanadasI3Bs/University of Minho, Portugal

28-SY-3: Dialybrid: Revolutionizing haemodialysis vascular accessSebastio van Uden，Stefania Riboldi，Davide Meroni，Valentina CattoBioengineering Laboratories Srl, Italy

28-SY-4: ExTherea: The future of healingSebastian Sjöqvist，Sophia Bou-GhannamTokyo Women’s Medical University, Japan

28-SY-5: ReverTome: Portable bioprinterRichard Cheng，Navid HakamiUniversity of Toronto, Canada

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27-SY Development and manufacture of silk-based medical devices: from basic systems to clinical useChairs: Antonella Motta, David Kaplan

27-SY-1: Regenerative silk ligament: scale up and regulatory strategy of a textile engineered silk implant for tissue regeneration of injured human ACL (anterior cruciate ligament) Bernhard Kuenburg，Andreas TeuschlMorphoMed, Austria

27-SY-2: Silk and polypeptide-mediated gene delivery system targeting to tumor cells and mitochondriaKeiji NumataRIKEN Center for Sustainable Resource Science, Saitama, Japan

27-SY-3: Functionalization of silk fibroin matrices using recombinant spider silk fusion proteins for developing bioactive wound dressingBiman B. Mandal，Dimple Chouhan，Naresh Thatikonda，Linnea Nileback，Mona Widhe，My HedhammarBiomaterial and Tissue Engineering Laboratory, Department of Biosciences and Bioengineering, Indian Institute of Technology Guwahati, India

27-SY-4: Silk fibroin scaffold loaded with hydrogen sulfide-releasing agent for bone tissue regenerationFrancesco Grassi，Laura Gambari，Rosasilvia Raggio，Walter Bonani，Emanuela Amore，Brunella Grigolo，Antonella MottaRizzoli Orthopaedic Institute, RAMSES Laboratory, Bologna, Italy

17:50 - 19:20

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★：Keynote


Symposia | September 6 (Thu), 2018

33-SY Translating skeletal muscle tissue engineering into clinicsChairs: Deana Mohr, Daniel Eberli

33-SY-1: Matrix Bound Nano-Versicles as Mediators of ECM-based Biological ActivityStephen F. BadylakDepartment of Surgery, University of Pittsburgh, Pittsburgh PA, USA

33-SY-2: A translational tissue engineering technology platform for skeletal muscle repair and regeneration: From biologically relevant animal models to regenerative rehabilitationGeorge J. ChristDepartment of Biomedical Engineering & Orthopaedic Surgery, University of Virginia, USA

33-SY-3: Clinical applications of skeletal muscle TE for urinary incontinenceDaniel Eberli，Deana MohrUrology Department, University Hospital Zurich, Switzerland

33-SY-4: MSCs delivered using structurally optimized hydrogels enhance skeletal muscle regeneration by paracrine mechanismsTaimoor H. Qazi，Michael Fuchs，David Mooney，Georg Duda，Sven GeisslerJulius Wolff Institute, Charite Universitatsmedizin Berlin, Germany

33-SY-5: Engineering human iPSC-derived 3D skeletal muscle constructs for repair of volumetric muscle lossAlec Simon Tulloch Smith，Jonathan Hung Tsui，C. Travis Moerk，InYoung Choi，Hotae Lim，Gabsang Lee，Deok-Ho KimDepartment of Bioengineering, University of Washington, Seattle, USA / Institute for Stem Cell and Regenerative Medicine, University of Washington, Seattle, USA

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32-SY Biomaterials-Bio3D PrintingChairs: Wei Sun, Swee Hin Teoh

32-SY-1: Emerging Organ Models and Organ Printing for Regenerative MedicineAli KhademhosseiniDepartment of Bioengineering, Chemical Engineering, Radiology, USA / University of California-Los Angeles (UCLA), USA / Center for Minimally Invasive Therapeutics at UCLA, USA / California NanoSystems Institute at UCLA, USA

32-SY-2: A Gradient Hierarchical Scaffold Induces in situ Simultaneous Regeneration of Cartilage and BoneShengmin Zhang，Yingying Du，Jianglin Wang，Jun MaAdvanced Biomaterials & Tissue Engineering Center, Huazhong University of Science and Technology, Wuhan, China / Department of Biomedical Engineering, Huazhong University of Science and Technology, Wuhan, China

32-SY-3: Diameter of PCL fibers produced by means of additive manufacturing affects mechanical properties and response of human mesenchymal stem cells Joanna Maria Idaszek，Żaneta Górecka，Dorota Kołbuk，Adrian Chlanda，Jan Brinchman，Wojciech SwieszkowskiFaculty of Material Science and Engineering, Warsaw University of Technology, Warsaw, Poland

32-SY-4: Development of programmable drug delivery capsule with 3D bioprintingNoehyun Myung，Hyun-Wook KangSchool of Life Science, Ulsan National Institute of Science and Technology, Ulsan, Korea

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31-SY Advances in neural tissue engineering and regenerative medicineChairs: Kazunobu Sawamoto, Hideyuki Okano

31-SY-1: Challenge toward iPSCs based cell therapy and modeling of CNS disorders and Current Status of Regenerative Medicine in JapanHideyuki OkanoDepartment of Physiology, Keio University School of Medicine, Japan

31-SY-2: Endogenous and artificial scaffolds for neuronal migration and regeneration in the injured brainKazunobu SawamotoDepartment of Developmental and Regenerative Biology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan / Division of Neural Development and Regeneration, National Institute for Physiological Sciences, Japan

31-SY-3: Gold nanoclusters promote neuronal regeneration via regulating M2 microglial polarizationLan Xiao，Tianqing Liu，Yin XiaoInstitute of Health and Biomedical Innovation, Queensland University of Technology, Australia

31-SY-4: 3D Bioengineered Neural Tissue To Mitigate Acute Cerebral Inflammation After Brain Transplantation In Rats Volha Liaudanskaya，Dennis Jgamadze，Alexander N. Berk，David J. Bischoff，Ben J. Gu，Hannah Hawks-Mayer，Michael J. Whalen，H. Isaac Chen，David L. KaplanDepartment of Biomedical Engineering, Tufts University, Medford, MA, USA

07:50 - 09:20

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★：Keynote



36-SY Forefront of clinical study in craniofacial regeneration therapyChairs: Shinya Murakami, Masahiro Saito

36-SY-1: New Era of Periodontal Regenerative Therapy - From Cytokine Therapy to Stem Cell Therapy-Shinya Murakami，Masahide TakedachiDepartment of Periodontology, Osaka University Graduate School of Dentistry, Japan

36-SY-2: The establishment of safety and efficacy evaluation for allogeneic periodontal ligament derived multipotent mesenchymal stromal cell sheet with next-generation sequencerTakanori Iwata，Satoru Onizuka，Sung-Joon Park，Yuka Tsumanuma，Kenta Nakai，Yuichi Izumi，Tomohiro AndoInstitute of Advanced Biomedical Engineering and Science, Tokyo Women's Medical University, Tokyo, Japan / Department of Oral and Maxillofacial Surgery, Tokyo Women’s Medical University, Tokyo, Japan

36-SY-3: Tissue-engineered autologous cartilage for cleft lip-nose patientsKazuto HoshiOral and maxillofacial Surgery, Department of Sensory and Motor System Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan

36-SY-4: Evaluation of periodontal tissue regeneration by transplantation of adipose tissue-derived multi-lineage progenitor cells in a clinical studyMasahide Takedachi，Shinya MurakamiDepartment of Periodontology, Osaka University Dental Hospital, Osaka, Japan

36-SY-5: Periodontal tissue regeneration ability of adipose tissue derived multilineage progenitor cells upon allogeneic transplantationMasahiro Saito，Venkata Suresh，Masahide Takedachi，Shinya Murakami，Hanayuki Okura，Akifumi Matsuyama ， Keisuke HandaTohoku University, Japan

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35-SY ‘One Health’ - Translational regenerative medicine in the veterinary sectorChairs: Iris Ribitsch, Yoshinori Kasashima

35-SY-1: Scaffold-mediated repair of tendon injuries in large animal models that mimic human tendon disease – the good, the bad and the uglyRoger K.W. SmithDept of Clinical Sciences and Services, The Royal Veterinary College, London. UK

35-SY-2: How long do implanted mesenchymal stem cell exist at injury site in tendon tissue ? : a cell tracking studyYoshinori Kasashima，Norihisa Tamura，Taisuke Kuroda，Kentaro Fukuda，Atsushi TomitaClinical Veterinary Medicine Division, Equine Research Institute of Japan Racing Association, Tochigi, Japan

35-SY-3: MSC Therapy for Osteoarthritis: Status and ObstaclesFrank BarryRegenerative Medicine Institute, National University of Ireland Galway, Ireland

35-SY-4: Fetal articular cartilage regeneration versus adult fibrocartilaginous repair – the key to cartilage regeneration?Florien Jenner，Iris Ribitsch，Rupert L Mayer，Monika Egerbacher，Simone Gabner，Maciej M Kańduła，Julie Rosser，Eva Haltmayer，Ulrike Auer，Sinan Gültekin，Johann Huber，Andrea Bileck，David P Kreil，Christopher GernerVETERM, University Equine Hospital, University of Veterinary Medicine Vienna, Austria

35-SY-5: Differences between species may limit the use of serum-free media across species- a lesson from the horseWalter Brehm，Susanna Schubert，Aline Hillmann，Janina BurkUniversity of Leipzig, Faculty of Veterinary Medicine, Department for Horses, Leipzig, Germany

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34-SY Recent Advance in Myocardial Tissue EngineeringChairs: Tatsuya Shimizu, Greg James Dusting

34-SY-1: CONSTRUCTING VASCULARISED HUMAN CARDIAC TISSUE FROM STEM CELLS WITH ELECTRICAL STIMULATIONGreg James Dusting，Damian H Hernandez，Robert Shepherd，Raymond CB Wong，Alice Pebay，Wayne A Morrison，Shiang Y LimCentre for Eye Research Australia, University of Melbourne, Australia / Departments of Surgery, Medicine and Medical Bionics, University of Melbourne, Australia / O’Brien Institute Department, St Vincents Institute, Melbourne, Australia

34-SY-2: Engineering of vascularized transplantable cardiac tissuesHidekazu SekineInstitute of Advanced Biomedical Engineering and Science, Tokyo Women's Medical University, Japan

34-SY-3: Lactate promotes cardiac tissue regenerationJesus Ordono，Soledad Pérez-Amodio，Lourdes Sánchez-Cid，Maria Valls-Margarit，Miguel Angel Mateos-Timoneda，Elena Martínez，Elisabeth EngelInstitute for Bioengineering of Catalonia (IBEC), The Barcelona Institute of Science and Technology, Barcelona, Spain / CIBER Bioengineering, Biomaterials and Nanotechnology, Spain

07:50 - 09:20

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★：Keynote

Time Room 7 (D) Room 8 (E) Room 9 (C-2)

Symposia / Oral Presentations | September 6 (Thu), 2018

39-O TERM for bone&cartilageChairs: Masaya Nakamura，Maulo Alini

39-O-1: Direct Reprogramming of Human Dermal Fibroblasts into Osteoblasts using Cell Penetrating Peptide, 30Kc19Janet Kwon，Seung Hyun Kim，GwangLi Kate Park，Hwajin Lee，Nathaniel HwangInterdisciplinary Program in Bioengineering, Seoul National University, Seoul, Korea

39-O-2: Application of MRI for Localization of Neocartilage on Human Auricular Chondrocyte-seeded Polymeric ScaffoldsQing Yu，Robin Childs，William Landis，Frank Reinauer，Stefanie Grom，Tobias Wolfram，Robert Clements，John Shelestak，Noritaka Isogai, Ananth MurthyAkron Children's Hospital, USA

39-O-3: Engineering the chondrocytes derived from cartilaginous graft by platelet-rich fibrin scaffolds for cartilage regenerationTsung-Lin Yang，Chin-Chena Wong，Ya-Chuan Hsiao，You-Tzung ChenDepartment of otolaryngology, National Taiwan University, Taipei, Taiwan / Research Center for Developmental Biology and Regenerative Medicine, National Taiwan University, Taipei, Taiwan / Graduate Institute of Clinical Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan

39-O-4: Internalised Phosphatidylserine Liposomes Encourage Osteogenic Differentiation of Human Bone Marrow Stem Cells Through the SMAD Signalling PathwayWayne Nishio Ayre，Edward S Gait-Carr，Genevieve E Melling，Rachel J Waddington，Samuel L Evans，Deborah J Mason，Bronwen Evans，James C Birchall，Rhidian Morgan-Jones，Stephen P Denyer，Alastair J SloanSchool of Dentistry, Cardiff University, Cardiff, UK

39-O-5: Enhancing cartilage synthesis via GDF2 stimulation for aggregated chondroprogenitor cells loaded in melt electrospun writing microfiber meshesFlorencia Abinzano，Mylène de Ruijter，Ilyas Mahmood Khan，Riccardo Levato，Jos MaldaDepartment of Orthopedics, University Medical Center Utrecht, Utrecht, the Netherlands

39-O-6: Alternative strategies for the treatment of critical size bone defects using naturally occurring growth factorsHenriette Bretschneider，Mandy Quade，Anja Lode，Michael Gelinsky，Corina VaterUniversity Center of Orthopaedics and Traumatology, University Hospital Carl Gustav Carus at TU Dresden, Germany

39-O-7: Improved Cartilage Formation in a Functionally Graded Scaffold: an Ovine Animal StudyMaryam Tamaddon，Gordon Blunn，Chaozong LiuInstitute of Orthopaedic Musculoskeletal Science, University College London, London, UK

39-O-8: Human bone marrow mesenchymal stem cells: Intrinsic sex-linked differences, and markers to predict their bone forming potency in vivoMeadhbh Brennan，Bénédicte Brulin，Markus Rojewski，Audrey Renaud， Hubert Schrezenmeier，Pierre LayrolleHarvard School of Engineering and Applied Sciences, Harvard University, Cambridge, USA. / National Institute of Health and Medical Research (INSERM) PHYOS, Faculty of Medicine, University of Nantes, France

38-SY Reconstituting cell nicheChairs: Barbara Chan, Evelyn Yim

38-SY-1: Bioengineered stem cell niches Gordana Vunjak-Novakovic，Bohao Liu，John O'Neill，Jinho Kim， Kacey Ronaldson-BouchardColumbia University, New York, NY, USA

38-SY-2: Engineering cell niche with biomaterials topographies for stem cell differentiation and tissue engineeringEvelyn KF YimDepartment of Chemical Engineering, University of Waterloo, Waterloo, Canada

38-SY-3: Substrate Stiffness Influences Doxorubicin-Induced Growth Suppression via p53 ActivationKeiko Kawauchi，Hiroaki HirataFrontiers of Innovative Research in Science and Technology, Konan University, Hyogo, Japan

38-SY-4: Tissue Adhesive, Rapid Forming, and Sprayable ECM Hydrogel for Stem Cell Delivery Nathaniel S HwangSchool of Chemical and Biological Engineering, Seoul National University, Korea

38-SY-5: Multiphoton 3D microprinting of protein microstructures and micropatterns for cell niche studiesBarbara Pui ChanTissue Engineering Lab, Department of Mechanical Engineering, The University of Hong Kong, Hong Kong

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37-SY Electroactive Biomaterials and Electrostimulation in TERM applicationsChairs: Rui L Reis, Michael Monaghan

37-SY-1: Electroactive gellan gum based spongy-like hydrogels for skeletal muscle Tissue Engineering applications Vitor M. Correlo，Rui L Reis3B’s Research Group - Biomaterials, Biodegradables and Biomimetics, University of Minho, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, AvePark, Barco, Guimarães, Portugal / ICVS/3B’s - PT Government Associate Laboratory, Braga/Guimarães, Portugal / The Discoveries Centre for Regenerative and Precision Medicine, Headquarters at University of Minho, AvePark, Barco, Guimarães, Portugal

37-SY-2: Electrically Conductive Hybrid Hydrogels with Anisotropic Topographical Features for Engineering Functional Cardiac TissuesMehdi Nikkhah，Ali NavaeiSchool of Biological and Health Systems Engineering, Arizona State University, Tempe, AZ, USA

37-SY-3: 3D Bioprinted Functional and Contractile Cardiac Tissue ConstructsSang Jin Lee，Zhan Wang，James J Yoo，Anthony AtalaWake Forest Institute for Regenerative Medicine, Wake Forest School of Medicine, USA

37-SY-4: Electrically Conductive Multi-Dimensional Scaffolds with Controllable Architecture for Skeletal Muscle EngineeringMegane Beldjilali Labro，Alejandro Garcia，Firas Farhat，Murielle Dufresne，Fahmi Bedoui，Jean-François Grosset，Cecile Legallais ，Rachid JellaliCNRS, UMR 7338 Biomechanics and Bioengineering, Sorbonne Universités, Université de Technologie de Compiègne, France

37-SY-5: The effect of increasing dosage of atmospheric dielectric barrier plasma discharge (DBD) on the surface chemistry and topography on electrically conductive electrospun PLCL/PANI biomaterialsGareth Christopher Menagh，Dorian Dixon，Patrick Lemoine，Brian Meenan，Brian Rodriguez，George BurkeNanotechnology and Integrated BioEngineering Centre, Ulster University Jordanstown Northern Ireland, UK

07:50 - 09:20

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★：Keynote



43-SY Advanced skeletal regenerative therapies in the context of agingChairs: Darja Marolt Presen, Günter Lepperdinger

43-SY-1: Aging in Stem Cells: Lessons from Mesenchymal Stem Cells Gunter LepperdingerUniversity Salzburg, Dept. Biosciences, Austria

43-SY-2: Extracellular vesicles and miRNAs as members of the senescence associated secretory phenotype inhibit osteogenic differentiation and are biomarkers of osteoporosis Johannes Grillari，Matthias Hackl，Sylvia Weilner，Lucia Terlecki-ZaniewiczBOKU - University of Natural Resources and Life Sciences Vienna, Christian Doppler Laboratory on Biotechnology of Skin Aging / TAmiRNA GmbH, Austria

43-SY-3: Engineering functional vascularized skeletal muscle graftsWarren Grayson，Jordana Gilbert-Honick，Sarah SomersJohns Hopkins University, USA

43-SY-4: Using a Novel Histone Deacetylase Inhibitor to Enhance Human Bone Marrow Stromal Cell Osteogenic Differentiation In VitroKenny Man，Naveen Mekhileri，Ben Schon，Khoon Lim，Lin-Hua Jiang，Richard Foster，Tim Woodfield，Xuebin YangBiomaterials & Tissue Engineering Group, School of Dentistry, University of Leeds, UK

43-SY-5: Human induced pluripotent stem cells-based strategies for bone tissue engineering and regeneration during agingDarja Marolt Presen，Dominik Hanetseder，Laura Ogrin，Alexandra Larissa Stetco，Heinz RedlLudwig Boltzmann Institute for Experimental and Clinical Traumatology / Austrian Cluster for Tissue Regeneration, Austria

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42-SY 4D-Tissue Regeneration: Integration of Cells and Scaffolds in Three-Dimension and Temporal RegenerationChairs: Masaya Yamamoto, Michiya Matsusaki

42-SY-1: 3D fabrication of bioinspired structured bone substitutes for bone regenerationHala ZreiqatUniversity of Sydney, Australia

42-SY-2: Bone tissue engineering and regenerative medicine 2.0 --Paradigm shift from “Proof-of-concept” to “Proof-of-value”Zhi-Yong ZhangTranslational Research Centre of Regenerative Medicine and 3D Printing Technologies, Guangzhou Medical University / The Third Affiliated Hospital of Guangzhou Medical University, China

42-SY-3: Hybrid-spheroids incorporating ECM mimicking nanofibers for tuning stem cell functionsHeungsoo Shin，Taufig Ahmad，Jinkyu Lee，Hyeok Jun ShinDepartment of Bioengineering, Hanyang University, Korea

42-SY-4: Temporal control of 3D tissue morphogenesis in artificial cellular microenvironments Takuya MatsumotoOkayama University, Okayama, Japan

42-SY-5: Treatment of hypoxic brain injury by exosomes from adipose-derived stem and progenitor cellsChia-Ching Wu，Chia-Wei Huang，Tzu-Chieh HuangDepartment of Cell Biology & Anatomy, University of Cheng Kung, Tainan, Taiwan

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41-SY Clinical translation of tissue engineering techniques using various biomaterialsChairs: Yasuhiko Tabata, Noritaka Isogai

41-SY-1: Clinical Experiences of Tissue Engineered Vascular Grafts in Pediatric Heart SurgeryToshiharu ShinokaDepartment of CT Surgery, Nationwide Children's Hospital / Ohio State university, USA

41-SY-2: Development of highly purified medical gelatin called beMatrixYosuke Hiraoka，Hiroyuki Ida，Monika Patel，Hiroshi TsukamotoResearch and Development Center, Nitta Gelatin Inc., Japan

41-SY-3: Clinical translation of bone regeneration using rhFGF-2-impregnated gelatin hydrogel for early-stage osteonecrosis of the femoral headYutaka KurodaDepartment of Orthopaedic Surgery, Graduate School of Medicine, Kyoto University, Kyoto, JAPAN

41-SY-4: The regeneration facilitating effects of basic fibroblast growth factor impregnated biodegradable gelatin hydrogel as a novel therapeutic strategy for facial nerve paralysisHiroyuki Yamada，Naohito Hato，Yasuhiko TabataDepartment of Otorhinolaryngology, Head and Neck Surgery, Ehime University, Japan

41-SY-5: Tissue engineering technology of bFGF slow release system for various plastic surgical reconstructionsNoritaka Isogai，Yu Sueyoshi，Tadaaki Morotomi，Hirohisa KusuharaDepartment of Plastic and Reconstructive Surgery, KINDAI University Faculty of Medicine, Osaka, Japan

14:30 - 16:00

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★：Keynote



46-SY Towards clinical development of advanced nerve conduits for peripheral nerve regenerationChairs: Srinivas Madduri, Antonio Salgado

46-SY-1: Engineering the trophic and topographical cues for nerve regenerationSrinivas Madduri Department of Biomedical Engineering, University of Basel, Switzerland

46-SY-2: Rat facial nerve regeneration using hybrid polyglycolic-acid (PGA)-collagen nerve conduits filled with adipose-derived stem cells and stromal vascular fractionsMari Shimizu，Hajime MitsumineDepartment of Plastic and Reconstructive Surgery, Tokyo Women's Medical University Yachiyo Medical Center, Chiba, Japan

46-SY-3: The efficacy of a scaffold-free Bio 3D conduit developed from dermal fibroblasts on peripheral nerve regeneration in a canine ulnar nerve injury modelSadaki Mitsuzawa，Ryosuke Ikeguchi，Tomoki Aoyama，Hisataka Takeuchi，Hirofumi Yurie，Hiroki Oda，Souichi Ohta，Manami Tsuji，Shizuka Akieda，Koichi Nakayama，Shuichi MatsudaDepartment of Orthopaedic Surgery, Kyoto University Graduate School of Medicine, Kyoto, Japan

46-SY-4: The Impact of Autologous Nerve Graft Phenotype and Extracorporeal Shockwave Therapy on Peripheral Nerve Regeneration in the Rat David Hercher，Christina M.A.P Schuh，Johannes Heinzel，Michaela Stainer，James Ferguson，Rudolf Hopf，László Gal，Thomas Hausner，Heinz RedlLudwig Boltzmann Institute for Experimental and Clinical Traumatology / Austrian Cluster for Tissue Regeneration, Austria

46-SY-5: Impact of Stem Cells Secretome and ECM-Like Hydrogels in Axonal Growth and Spinal Cord Injury RepairAntonio SalgadoLife and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal / ICVS/3B's - PT Government Associate Laboratory, Braga, Guimarães, Portugal

46-SY-6: Synergistic Local Delivery of Gene Recombinant Stem Cells and Methylprednisolone after Severe Rat Spinal Cord InjuryLiming Li，Jianqing GaoInstitute of Pharmaceutics, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou Zhejiang, China / Dr. Li Dak Sum & Yip Yio Chin Center for Stem Cell and Regenerative Medicine, Zhejiang University, Hangzhou, Zhejiang, China

46-SY-7: Catalytic function of cerium oxide nanoparticles effective for healing of injured rat spinal cordJungju Seo，Jong-Wan Kim，Rajendra kumar singh，Jung-Hwan Lee，Hae-Hyoung Lee，Jung Keun Hyun，Hae-Won KimInstitute of Tissue Regeneration Engineering (ITREN), Dankook University, Cheonan, Korea / Department of Nanobiomedical Science & BK21 PLUS NBM Global Research Center for Regenerative Medicine Research Center, Dankook University, Cheonan, Korea

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45-SY Elastin in regenerative medicine: biomaterials and biosynthesisChairs: Willeke F. Daamen, Anthony S. Weiss

45-SY-1: Vascular grafts that maintain patency, retain tensile properties and demonstrate biological performanceAnthony S. Weiss，Richard WangCharles Perkins Centre, University of Sydney, NSW, Australia

45-SY-2: Biomaterials containing mature elastin fibers and hydrolysates thereofWilleke F. Daamen，Danique J. Hof，Elly M.M. Versteeg，Toin H. van KuppeveltDept. of Biochemistry, RIMLS, Radboud university medical center, Nijmegen, The Netherlands

45-SY-3: Multifunctional, JNK-2 Gene Silencing Nanotherapeutics for Elastic Matrix Regenerative Repair in Abdominal Aortic AneurysmsAnand Ramamurthi，Sarah Carney，Andrew Camardo，Thomas Broekelmann，Robert P. MechamDepartment of Biomedical Engineering, Cleveland Clinic, Cleveland, OH, USA

45-SY-4: Elastin in cardiovascular biohybridsPetra MelaDepartment of biohybrid and medical textiles, AME-Applied Medical Engineering, RWTH Aachen University, Aachen, Germany

45-SY-5: Molecular modeling of elastin biomaterials Anna Tarakanova，Giselle C. Yeo，Wenwen Huang，Clair Baldock，Anthony S. Weiss，David L. Kaplan，Markus J. BuehlerDepartment of Civil and Environmental Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA

45-SY-6: Electrospun scaffolds based on two complementary "on the fligth clickable " Elastin-like Recombinamers for skin regenerationIsrael Gonzalez de Torre，Arturo Ibañez Fonseca，Luis Quintanilla，Matilde Alonso，Jose Carlos Rodriguez CabelloTechnical Proteins NanoBiotechnology, research department., Valladolid, Spain / G.I.R BIOFORGE, Universidad de Valladolid. Valladolid, Spain

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44-SY In vivo Bioreactor ? In situ Tissue RegenerationChairs: Lorenzo Moroni, To be announced

44-SY-1: In Vivo Bioreactors for Craniofacial Tissue RegenerationAntonios G. Mikos，Mark E. Wong，Alexander M. TataraDepartment of Bioengineering, Rice University, Houston, Texas, USA

44-SY-2: iBTA-based Regenerative MedicineYasuhide NakayamaDepartment of Artificial Organs, National Cerebral and Cardiovascular Center, Japan

44-SY-3: In Situ Tissue Regeneration of a vascular access graftLorenzo Moroni，Joris RotmansMERLN Institute for Technology-Inspired Regenerative Medicine, Maastricht University, The Netherlands

44-SY-4: Decellularized Human Skin As Biological Scaffold for the Regeneration of Human Heart By Resident Cardiac Progenitor CellsClotilde Castaldo，Franca Di Meglio，Veronica Romano，Fabrizio Schonauer，Diana Massai，Immacolata Belviso，Daria Nurzynska，Anna Maria Sacco，Mariagrazia Di Gennaro，Antonia Carfora，Angelica Avagliano，Stefania MontagnaniDepartment of Public Health, University of Naples Federico II, Italy

44-SY-5: Spatially Patterned Atheroprotective Vascular Grafts for Enhanced PatencyKarina Nakayama，Masashi Kawamura，Hanjay Wang，Hanway Wang，Joseph Woo，Ngan HuangCardiothoracic Surgery, Stanford University, Stanford, CA, USA / Stanford Cardiovascular Institute, Stanford University, Stanford, CA, USA / Veterans Affairs Palo Alto Health Care System, Palo Alto, CA, USA

14:30 - 16:00

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★：Keynote



49-O TERM for abdominal organsChairs: Shuji Terai，Tracy Grikscheit

49-O-1: An in vitro System to Model the Effects of Fibrosis on Liver DevelopmentShay Soker，Matthew D Brovold，Dipen Vyas，Pedro M BaptistaWake Forest University School of Medicin, USA / Wake Forest Institute for Regenerative Medicine, USA

49-O-2: Bioprinted Liver Organoids in a Perfusion Bioreactor as Model to Evaluate Drug-Induced Liver ToxicityRiccardo Levato，Kerstin Schneeberger，Pedro Costa，Vivian Lehman，Monique Schuddeboom，Jos Malda，Bart SpeeDepartment of Orthopaedics, University Medical Center Utrecht, Utrecht, the Netherlands

49-O-3: Pig Spleen as the site of human hepatocyte regenerationEiji Kobayashi，Shin EnosawaDepartment of Organ Fabrication, Keio University School of Medicine, Tokyo, Japan

49-O-4: Bioengineered human fetal livers: a new tool for the production of hematopoietic progenitor cellsPilar Sainz-Arnal，Pedro M BaptistaHealth Research Institute of Aragon (IIS Aragon), Zaragoza, Spain / Aragon Health Sciences Institute (IACS), Zaragoza, Spain

49-O-5: The paracrine effect of human visceral adipose tissue on primary human hepatic stellate cells in human 3D liver scaffoldsKrista Rombouts，Zhenzhen Zhang，Lore Meelberghs，Luca Frenguelli，Hannelie Korf，Massimo Pinzani，David Cassiman，Giuseppe Mazza，Schalk Van Der MerweUniversity College London (UCL), Institute for Liver and Digestive Health, London, UK

49-O-6: Primary human Hepatic Stellate Cell phenotype is differently regulated by pro-fibrogenic and pro-inflammatory stimuli in cirrhotic and healthy human liver 3D ECM scaffolds Krista Rombouts，Elisabetta Caon，Zhenzhen Zhang，Luca Frenguelli，Walid Al-Akkad，Giuseppe Mazza，Massimo PinzaniUniversity College London (UCL), Institute for Liver and Digestive Health, London, UK

48-SY In situ tissue regeneration: endogenous stem cell recruitment, bioactive signals, and biomaterial designChairs: Sang Jin Lee, James J. Yoo

48-SY-1: In Situ Tissue Regeneration: A Translational Strategy in Regenerative MedicineJames J. YooWake Forest Institute for Regenerative Medicine, USA

48-SY-2: The interaction of biomaterials and stem cells in tissue regenerationGuillermo Bauza，Francesca Taraballi，Lewis Francis，Bruna Corradetti，Silvia Minardi，Aaron Shi，Ennio TasciottiCenter for Biomimetic Medicine, Houston Methodist Research Institute, Houston Methodist Hospital, Houston, TX, USA / Department of Orthopedics and Sports Medicine, Houston Methodist Hospital, Houston, TX, USA / Centre for Nanohealth, Swansea University, Swansea, Wales, UK

48-SY-3: A heparan sulfate device for the regeneration of osteochondral defectsXiaoman Luo，Jonathan H Lee，Xiafei Ren，Tuanchun Tan，Raymond A Smith，Kunchithapadam Swaminathan，Sakthivel Sekar，Kishore Bhakoo，Victor Nurcombe，James H Hui，Simon M CoolInstitute of Medical Biology, Agency for Science, Technology and Research (A*STAR), Singapore

48-SY-4: CXCR4 Antagonism Endogenously Mobilises Stem and Progenitor Cells and Rescues Non-union DevelopmentRichard Meeson，Anita Sanghani-Kerai，Melanie Coathup，Gordon BlunnInstitute of Orthopaedics, Divison of Survery & Interventional Science, University College London, UK

48-SY-5: A neuropeptide, Substance-P, directly induces tissue-repairing M2 like macrophages by activating the PI3K/Akt/mTOR pathway even in the presence of IFN γYoungsook Son，Ji-Eun Lim，EunKyung ChungDepartment of Genetic Engineering, Kyung Hee University, Seoul, Korea / Graduate School of Biotechnology, Kyung Hee University, Seoul, Korea / Kyung Hee Institute of Regenerative Medicine, Korea

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47-SY Silk biomaterial matricesChairs: Subhas C. Kundu, James Goh

47-SY-1: Silk – from Textiles to MedicineDavid L KaplanTufts University, USA

47-SY-2: To Improve Regeneration of Corneal Endothelial Cells Using the Taurine/Silk Fibroin Film Gilson Khang ，Hayan Jeon，Hansol Kim，Jeongeun Song，Giwon LeeDepartment of BIN Convergence Technology, Department of Polymer Nano Science & Technology, Chonbuk National University, Jeonju, Korea

47-SY-3: Natural biomaterials and emerging 3D cancer models: engineering the microenvironmentSubhas C. Kundu，Sara Amorim，Banani Kundu，Virginia Brancato，David Caballero，Ricardo A. Pires，Joaquim M. Oliveira，Vitor M. Correlo，Rui L. Reis3B's Research Group - Biomaterials, Biodegradables and Biomimetics, University of Minho, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, AvePark, Barco, Guimarães, Portugal / ICVS/3B's - PT Government Associate Laboratory, Braga/Guimarães, Portugal

47-SY-4: Sustained Local Release of NGF from a Chitosan-Sericin Composite Scaffold for Treating Chronic Nerve CompressionZheng Wang，Lin Wang，Lei Zhang，Wen YangResearch Center for Tissue Engineering and Regenerative Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology / Dept. of Gastrointestinal Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, China

47-SY-5: Enzymatically-crosslinked silk fibroin hierarchical scaffolds for osteochondral tissue engineeringMiguel Oliveira，Viviana Ribeiro，Rui L. Reis3B's Research Group, Univ Minho, Portugal

47-SY-6: Advanced mechanical analysis for protein-based biomaterialsJuan Guan，Behnaz Aghaei-Ghareh-Bolagh，Anthony S. WeissSchool of Materials Science and Engineering, Beihang University, Beijing, China

14:30 - 16:00

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★：Keynote

Symposia / Oral Presentations | September 6 (Thu), 2018Time Room 7 (D) Room 8 (E) Room 9 (C-2)

49-O-7: Glycosaminoglycans (GAGs) in pathological extracellular matrix networksEva Brauchle，Jana Kasper，Ruben Daum，Nicolas Schierbaum，Claudius Falch，Andreas Kirschniak，Tilman E. Schäffer，Katja Schenke-LaylandDepartment of Women's Health, Research Institute for Women's Health, Eberhard-Karls-University of Tuebingen / Fraunhofer Institute for Interfacial Engineering and Biotechnology (IGB), Department of Cell and Tissue Engineering, Stuttgart, Germany

49-O-8: Crohn’s disease patient-derived small intestinal organoids reveal disease-status related modification of stem cell propertiesKohei Suzuki，Tatsuro Murano，Yui Hiraguri，Junichi Takahashi，Hiromichi Shimizu，Sho Anzai，Konomi Kuwabara，Ami Kawamoto，Fumiaki Ishibashi，Shiro Yui，Kiichiro Tsuchiya，Tetsuya Nakamura，Kazuo Ohtsuka，Mamoru Watanabe，Ryuichi OkamotoDepartment of Gastroenterology and Hepatology, Tokyo Medical and Dental University, Tokyo, Japan

49-O-9: Microchip-based spheroid formation enhances differentiation function and engraftment of insulin-producing cells derived from human liver cells for diabetes treatmentYuna Lee，Song Cheol Kim，In Kyong ShimBiomedical Engineering Research Center, Asan Institute for Life Sciences, Asan Medical Center, Korea


★：Keynote



53-SY Regeneration of the Anterior Cruciate Ligament - Current Status and ChallengesChairs: Thomas Nau, Andreas Teuschl

53-SY-1: Regeneration of Functional Tissue-engineered Anterior Cruciate Ligament James Goh，Thomas TehDepartment of Biomedical Engineering, National University of Singapore, Singapore / Department of Orthopaedic Surgery, National University of Singapore, Singapore / NUSTEP, Life Sciences Institute, National University of Singapore, Singapore

53-SY-2: Scaffold-less Tissue Engineering Technologies To Repair Anterior Cruciate Ligament InjuriesLisa M LarkinDepartment of Physiology and Biomedical Engineering, University of Michigan, Ann Arbor, Michigan, USA

53-SY-3: Engineering Tissue ConnectivityHelen LuBiomedical Engineering, Columbia University, USA

53-SY-4: Anterior Cruciate Ligament Regeneration using the Silk-based “RegACL” ScaffoldAndreas Teuschl，Partrick Heimel，Xavier Monforte，Sylvia Nürnberger，Stefan Tangl，Martijn van Griensven，Heinz Redl，Thomas NauDepartment of Biochemical Engineering, University of Applied Sciences Technikum Wien, Vienna, Austria / AUVA Research Center, Vienna, Austria

52-SY Scaffold-free strategies to engineer tissue for regenerative medicineChairs: Eben Alsberg, Heungsoo Shin

52-SY-1: Identification of synergistic stimuli to guide spheroid functionKent LeachDepartment of Biomedical Engineering, Univ. of California, Davis, USA

52-SY-2: Cell Encapsulation by Nanofilms for In Vitro Construction of 3D-Tissue ModelsMichiya MatsusakiGraduate School of Engineering, Osaka University / JST-PRESTO, Japan

52-SY-3: Tissue engineering by modular fabrication and cellular self-assemblyMarsha RolleDepartment of Biomedical Engineering, Worcester Polytechnic Institute, Worcester, MA, USA

52-SY-4: Smart hydrogel platforms for high-throughput production and culture of size-controlled multi-cellular spheroidsHeungsoo Shin，Yu Bin Lee，Eun Mi Kim，Hayeon ByunDepartment of Bioengineering, Hanyang University, Korea

52-SY-5: Delivering instructive cues to development-mimetic cellular condensations for modular engineering of complex tissuesEben AlsbergDepartment of Biomedical Engineering and Orthopaedic Surgery, Case Western Reserve University, Cleveland, OH, USA

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51-SY Discovering Novel Tissue and Blood Proteins for RegenerationChairs: Jeremy Mao, Yasuhiko Tabata

51-SY-1: A Regenerative Medicine Approach for the Treatment of Volumetric Muscle Loss in HumansStephen Francis BadylakDepartment of Surgery, University of Pittsburgh, Pittsburgh, PA, USA

51-SY-2: Controlled Release of Proteins and PRP for Tissue Regeneration Yasuhiko TabataDepartment of Biomaterials, Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto, Japan

51-SY-3: Modulation of the osteoimmune environment by biomaterials and bone growth factors in osteogenesisYin XiaoQueensland University of Technology, Australia

51-SY-4: Macrophage cells secrete factors that orchestrate bone repair Benjamin A. Alman，Linda Vi，Gurpreet Baht，Yasuhito YaharaDuke University, USA

51-SY-5: Contrasting tissue and blood proteins for tissue regeneration Jeremy MaoColumbia University, USA

16:30 - 18:00

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★：Keynote



56-SY Tissue Engineering and beyond in peripheral nerve regeneration - from supportive biomaterials and cells to functional recoveryChairs: Kirsten Haastert-Talini, James B. Phillips

56-SY-1: Living artificial replacement tissue for peripheral nerve repairJames B. PhillipsUCL Centre for Nerve Engineering, University College London, London, UK

56-SY-2: Keynote: Accelerating translation of peripheral nerve tissue engineering approaches into real products by choosing meaningful pre-clinical modelsKirsten Haastert-TaliniInstitute of Neuroanatomy and Cell Biology, Hannover Medical School, Hannover, Germany / Center for Systems Neuroscience (ZSN) Hannover, Hannover, Germany

56-SY-3: The Impact of Autologous Nerve Graft Phenotype and Extracorporeal Shockwave Therapy on Peripheral Nerve Regeneration in the Rat David Hercher，Christina M.A.P Schuh，Johannes Heinzel，Michaela Stainer，James Ferguson，Rudolf Hopf，László Gal，Thomas Hausner，Heinz RedlLudwig Boltzmann Institute for Experimental and Clinical Traumatology, Austria / Austrian Cluster for Tissue Regeneration, Austria

56-SY-4: CRISPR-based activation of adipose stem cell endogenous gene expression for peripheral nerve regenerationMu-Nung Hsu，Vu Anh Truong，Kai-Lun Huang，Fu-Jen Yu，Nguyễn Thị Kiều Nương，Yu-Chen HuDepartment of Chemical Engineering, National Tsing Hua University, Hsinchu, Taiwan

56-SY-5: Centella Asiatica Induced Mesenchymal Stem Cells (MSCs) Promote Regeneration of Critical Defect of Peripheral Nerve in an Animal ModelHanita Mohd Hussin，Mahazura Mat Lawi，Nor Hazla Mohamed Haflah，Abdul Yazid Mohd Kassim，Ruszymah Haji Idrus，Yogeswaran LokanathanTissue Engineering Centre, Universiti Kebangsaan Malaysia Medical Centre, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia

56-SY-6: Effect of MARCKS peptide functionalized intraluminal collagen fibre-based conduit on a critical gap model of peripheral nerve injurySecil Demir，William Daly，Sahana Ganesh，Abbah Akogwu Sunny，Kyriakos Spanoudes，Isma Lisa Mohd Isa，Dimitrios Zeugolis，Huan Wang，Anthony Windebank, Abhay PanditNational University of Ireland, Galway, Ireland

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55-SY Animal models in clinical translation and commercialization of tissue engineering and regenerative medicine therapies - Myths and realityChairs: Dimitrios I. Zeugolis, Manuela Gomes

55-SY-1: Animal models in clinical translation and commercialization of tissue engineering and regenerative medicine therapies – Myths and reality Dietmar Werner HutmacherCentre in Regenerative Medicine, Institute of Health and Biomedical Innovation, Queensland, Australia / ARC Training Centre In Additive Biomanufacturing, Queensland University of Technology (QUT), Brisbane, QLD, Australia / Institute for Advanced Study, Technische Universität München, Garching, Germany

55-SY-2: Upsizing the lab: experiences with large animal translational models of tendinopathies Jay DudhiaClinical Sciences and Services, Royal Veterinary College, University of London, U.K.

55-SY-3: Comprehensive assessment of inflammatory proteins expressed by primary peripheral blood mononuclear cells - a comparison of the inflammatory reaction of sheep, horses and humansIris Ribitsch，Michele Fenu，Lukas Janker，Andrea Bileck，Rupert Mayer，Christopher Gerner，Florien JennerVETERM, University Equine Hospital, University of Veterinary Medicine Vienna, Austria

55-SY-4: Design and evaluation of electrospun structured polycaprolactone biomaterials for annulus fibrosus repairMaude Diane Gluais，Johann Clouet，Marion Fusellier，Cyrille Decante，Luc Terreaux，Constantin Moraru，Joëlle Veziers，Julie Lesoeur，Sing Yian Chew，Jérôme Guicheux，Catherine Le VisageInserm, UMR 1229, RMeS, Regenerative Medicine and Skeleton, University of Nantes, ONIRIS, Nantes, France / Université de Nantes, UFR Odontologie, Nantes, France

55-SY-5: Stem Cell Based Bioengineering Strategies Using Magnetic Tools Towards Tendon RegenerationAna I. Goncalves，Márcia T Rodrigues，Alicia J El Haj，Rui L Reis，Manuela E Gomes3B’s Research Group - Biomaterials, Biodegradables and Biomimetics, University of Minho, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, Avepark - Zona Industrial da Gandra, Barco, Guimarães, Portugal / ICVS/3B’s - PT Government Associate Laboratory, Braga, Guimarães, Portugal

55-SY-6: CXCR4 Antagonism Endogenously Mobilises Stem and Progenitor Cells and Rescues Non-union DevelopmentRichard Meeson，Anita Sanghani-Kerai，Melanie Coathup，Gordon BlunnInstitute of Orthopaedics, Divison of Survery & Interventional Science, University College London, UK

55-SY-7: Accelerating wound healing in the splinted nude mouse model with an engineered modular cell delivery constructKyriakos Alexandros Spanoudes，Diana Gaspar，Stefanie Korntner，Yves Bayon，Dimitrios ZeugolisRegenerative, Modular and Developmental Engineering Laboratory (REMODEL), National University of Ireland Galway / Centre for Research for Medical Devices (CURAM), National University of Ireland, Galway, Ireland

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54-SY Cell manufacturability in cell manufacturing processChairs: Masahiro Kino-oka, Tatsuya Shimizu

54-SY-1: Flexible modular platform for cell production based on cell manufacturabilityMasahiro Kino-okaDepartment of Biotechnology, Osaka University, Osaka, Japan

54-SY-2: Manufacturability in Cell-Sheet-Based Tissue EngineeringTatsuya ShimizuInstitute of Advanced Biomedical Engineering and Science, Tokyo Women's Medical University, Tokyo, Japan

54-SY-3: A pneumatic pressure bioreactor for applying dynamic mechanical loads to cell culture platesJames R HenstockInstitute of Ageing and Chronic Disease, University of Liverpool, Liverpool, UK

54-SY-4: A 3D Printed Microfluidic Bioreactor to Engineering Biphasic Musculoskeletal ConstructRiccardo Gottardi，Giulio De Riccardis，Martina Avolio，Derek A. Nichols，Peter G. Alexander，Paolo Zunino，Manuela T. Raimondi，Rocky S. TuanUniversity of Pittsburgh, USA/ Fondazione Ri.MED, Italy

16:30 - 18:00

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★


★：Keynote



59-O ES and iPS cellsChairs: Akihiro Umezawa，Ranieri Cancedda

59-O-1: How Do Stem Cells Find Their Niche?Shukry James Habib，Sergi Junyent，Clare Garcin，Tung-Jui Trieu，James Szcerkowki，Ignacio Bordeu Weldt，Gunnar PruessnerCentre For Stem Cells and Regenerative Medicine, King's College London, UK

59-O-2: Acidity in the heart: how pH affects iPSC-derived cardiomyocytes and strategies to harness it for therapeutic interventionArianna Ferrini，Limor Zwi-Dantsis，Stacey Skaalure，Lucia Massi，Nadia Rosenthal，Molly M StevensNational Heart and Lung Institute, Imperial College London, London, UK / British Heart Foundation Centre for Research Excellence, Imperial College London, London, UK

59-O-3: Quantitative Assessment of Pluripotent Stem Cells by an Improved RM-DIC Imaging SystemKen Nishimura，Hiroshi Ishiwata，Yuta Sakuragi，Yohei Hayashi，Aya Fukuda，Koji HisatakeLaboratory of Gene Regulation, Faculty of Medicine, University of Tsukuba, Ibaraki, Japan

59-O-4: Analysis of structural and functional parameters in mesenchymal and induced pluripotent stem cells during differentiation using new methods of high-resolution microscopy and fluorescence imagingAleksandra V Meleshina，Alena S Bystrova，Varvara V Dudenkova，Erdem B Dashinimaev，Elena V ZagaynovaInstitute of Biomedical technologies, Nizhny Novgorod State Medical Academy, Nizhny Novgorod, Russia

59-O-5: Visible laser-induced detachment of iPS-derived cardiac cells from Gold Nanoparticle-embedded Collagen GelTakeshi Kawano，Kaede Yokoyama，Kenji Takatsuka，Yusuke Taki，Yuji Haraguchi，Katsuhisa Matsuura，Tatsuya Shimizu，Yusuke Nakajima，Chie KojimaR&D Division, Nikon Corporation, Kanagawa, Japan

59-O-6: Towards Building a Patient-Specific Endothelium for Patients with Peripheral Artery DiseaseBin Jiang，Xinlong Wang，Chongwen Duan，Melina Kibbe，Guillermo AmeerBiomedical Engineering Department, Northwestern University, Evanston, IL, USA / Center for Advanced Regenerative Engineering, Northwestern University, Evanston, IL, USA

59-O-7: Spatio-temporally patterned neuroectoderm tissues recapitulate early neural morphogenesis and pathogenesisGeetika Sahni，Shu-Yung Chang，Jeremy Teo Choon Meng，Kagistia Hana Utami，Mahmoud A. Pouladi，Yi-Chin TohDepartment of Biomedical Engineering, National University of Singapore, Singapore

59-O-8: Embryonic stem cell-derived hapatocyte-based therapy to patients with hyperammonemiaAkihiro UmezawaCenter for Regenerative Medicine, National Research Institute for Child Health and Development, Japan

59-O-9: Equine stem cell therapy for musculoskeletal injuriesKyu-Shik Jeong，Myung-Jin Chng，Ahmed K. Elfadl，Arif Ullah，Soong-Gu Ghim，Ji-Yoon Son，Sul-Gi Jeon，Yong-Deuk Kim，Gil-Jae JoDepatment of Veterinary Medicine, Kyungpook National University, Daegu, Korea / Stem Cell Therapeutic Research Institute, Kyungpook National University, Daegu, Korea

58-SY Recapitulating tumor microenvironments to screen biotherapeuticsChairs: Daniela Loessner, Carsten Werner

58-SY-1: Bone mineral matrix: An underappreciated regulator of metastatic breast cancer?Claudia Fischbach-TeschlMeinig School of Biomedical Engineering, Cornell University, Ithaca, NY, USA

58-SY-2: 3D bioprinting of brain tumour models: multi-lineage glioma constructs to investigate tumour biology and drug responsesNicholas R LeslieInstitute of Biological Chemistry, Biophysics and Bioengineering, Heriot Watt University, Edinburgh, UK

58-SY-3: Glycosaminoglycan-based biohybrid hydrogels for mimicking tumor microenvironments in vitroCarsten WernerMax Bergmann Center of Biomaterials, Leibniz Institute of Polymer Resarch & TU Dresden, Germany

58-SY-4: A 3D tumour microenvironment regulates cancer cell growth and gene expression patternsDaniela Loessner，Anja Rockstroh，Boris M Holzapfel，Judith A Clements，Dietmar W HutmacherBarts Cancer Institute, Queen Mary University of London, London, United Kingdom / Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Australia

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57-SY Multi-parametric quantitative imaging of live cells in 3D tissue modelsChairs: Ruslan I. Dmitriev, Ying Yang

57-SY-1: FLIM-PLIM microscopy toolkit for tissue engineering of the intestinal organoidsRuslan I. Dmitriev，Dmitri B. Papkovsky，Irina A. OkkelmanSchool of Biochemistry and Cell Biology, University College Cork, Ireland

57-SY-2: Marker-independent monitoring tools for online inline cell and tissue analysisKatja Schenke-LaylandDept. of Women's Health, Eberhard Karls University, Tuebingen, Germany / The Natural and Medical Sciences Institute (NMI) at the University of Tuebingen, Reutlingen, Germany / Department of Medicine, Cardiology, Cardiovascular Research Laboratories, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA

57-SY-3: Tracking tissue turnover and scaffold degradation in 3D constructsYing Yang，Rachel Gater，Alicia J El HajKeele University, UK

57-SY-4: X-Ray Phase Contrast Imaging of Implanted BiomaterialsEric Brey，Alyssa Appel，Sami Somo，Mark AnastasioBiomedical Engineering, University of Texas at San Antonio, USA / Audie L. Murphy VA Hospital

57-SY-5: Longitudinal Evaluation of Tissue Engineered Articular Cartilage using Non-destructive Multimodal Imaging: Effects of Latent Transforming Growth Factor- β1Anne K. Haudenschild，Benjamin E. Sherlock，Xiangnan Zhou，Clay S. Sheaff，Jerry C. Hu，J. Kent Leach，Laura Marcu，Kyriacos A. AthanasiouDepartment of Biomedical Engineering, University of California at Davis, Davis, CA, USA

16:30 - 18:00

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★：Keynote


Symposia | September 7 (Fri), 2018

63-SY Research Challenges in Stem Cell Culture and Differentiation on Biomaterials targeting for Stem Cell TherapyChairs: Akon Higuchi, Anamaria Orza

63-SY-1: Biomimetic ECM Scaffolds Prepared from 3D Cell Culture for Controlling Stem Cell DifferentiationGuoping Chen，Rong Cai，Naoki KawazoeResearch Center for Functional Materials, National Institute for Materials Science, Tsukuba, Japan

63-SY-2: Completely xeno-free generation of human induced pluripotent stem cells on the surface immobilized with ECM and ECM-derived oligopeptide using non-integrated Sendai virus vectorAkon Higuchi，Hsing-Fen LiDepartment of Chemical and Materials Engineering, National Central University, Jhong-li, Taiwan / The Eye Hospital of Wenzhou Medical University, Wenzhou, China / Wenzhou Institute of Biomaterials and Engineering, Wenzhou, China / Nano Medical Engineering Laboratory, RIKEN, Saitama, Japan / Department of Botany and Microbiology, King Saud University, Riyadh, Saudi Arabia

63-SY-3: Chitosan-based Biomaterials for Stemness Enhancement and Sustained Delivery of Adipose-Derived Stem CellsNai-Chen ChengDepartment of Surgery, National Taiwan University Hospital, Taiwan

63-SY-4: Revolutionary regeneration of damaged tissue including appreciable decrease in scar formation and skin color anomalies using nanomaterial’sAnamaria OrzaIndagoMed., LLC, Atlanta, GA / Emory University School of Medicine, Atlanta, GA, USA

63-SY-5: Effect of micro/nano-structure of biomaterials on stem cell differentiationChang JiangShanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai, China

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62-SY Biofabrication: from new technologies to clinical applicationsChairs: Aleksandr Ovsianikov, Koichi Nakayama

62-SY-1: Quality Control of 3D Printed Resorbable Implants: The 3D Printed Airway Splint ExampleSJ Hollister，SJ Crotts，H Ramaraju，CL Flanagan，RJ Morrison，A Les，RG Ohye，GE GreenCenter for 3D Medical Fabrication, Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA USA

62-SY-2: Cardiovascular Tissue Engineering using 3D Printing Technology Narutoshi HibinoDivision of Cardiac Surgery, Johns Hopkins Hospital, USA

62-SY-3: Quality aspects of regenerative medical productsYoshiaki MaruyamaPharmaceuticals and Medical Devices Agency, Tokyo, Japan

62-SY-4: Biofabrication: a new toolset to study biology in 3D with applications in regenerative medicine and in vitro models Lorenzo MoroniMERLN Institute for Technology-Inspired Regenerative Medicine, Maastricht University, The Netherlands

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61-SY National Projects and Organizational Approaches to Promote and Spread the Regenerative MedicineChairs: Yoji Sato, Kiyoshi Okada

61-SY-1: Academic Nation-wide Platform which delivers Regenerative Medicine to bedsideYoshiki SawaChief in Cardiovascular Surgery, OSAKA University, Japan / President, JSRM, Japan

61-SY-2: Activity of UK Catapult for commercialisation of Cell and Gene TherapyHidetoshi HoshiyaCell and Therapy Catapult, Guys Hospital, Great Maze Pond, London, UK

61-SY-3: A collaborative public/private partnership driving commercialization in regenerative medicineMichael MayCCRM, Canada

61-SY-4: To be announcedJeff RossMiromatrix, USA

09:30 - 11:00

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★：Keynote



66-SY Regenerative therapy for GI and HPB diseasesChairs: Junji Fukuda, Takahiro Ochiya

66-SY-1: Overview of liver regenerationShuji TeraiDivision of Gastroenterology and Hepatology, Graduate School of Medical and Dental Sciences, Niigata University, 1-757 Asahimachi-dori, Chuo-ku, Niigata, Japan

66-SY-2: Transplanting tissue-engineered epitherial cell sheets to esophageal mucosal defect for the prevention of severe stricturesShinichiro Kobayashi，Masayuki Yamato，Susumu EguchiDepartment of Surgery, Nagasaki University Graduate School of Biomedical Sciences, Japan

66-SY-3: Regenerative medicine for the treatment of inflammatory bowel diseaseRyuichi Okamoto，Mamoru WatanabeCenter for Stem Cell and Regenerative Medicine, Tokyo Medical and dental University, Tokyo, Japan / Department of Gastroenterology and Hepatology, Tokyo Medical and dental University, Tokyo, Japan

66-SY-4: Iron-regulatory mechanism of liver and functional organoidsHan-Sung JungYonsei University, Seoul, Korea

66-SY-5: Engineering approaches for small and large tissues based on oxygen supplyJunji FukudaGraduate School of Engineering, Yokohama National University, Yokohama, Japan

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65-SY Challenges to Stem Cell Therapy Development and Regulation in Dogs and CatsChairs: Kazuya Edamura, Masaharu Hisasue

65-SY-1: Regenerative medicine in veterinary field of Japan Masaharu HisasueLaboratory of Small Animall Internal Medicine, Azabu University, Kanagawa, Japan

65-SY-2: Generation of canine and feline pluripotent stem cells for application in regenerative medicineShingo HatoyaGraduate School of Life and Environmental Sciences, Osaka Prefecture University, Osaka, Japan

65-SY-3: Challenges to develop stem cell therapies in dogs using novel mesenchymal stem cells isolated from bone marrowNaoki FujitaLaboratory of Veterinary Surgery, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan

65-SY-4: Clinical application and future directions of mesenchymal stem/stromal cell therapy for spinal cord injury in dogsHidetaka NishidaDepartment of Veterinary Science, Osaka Prefecture University, Osaka, Japan

65-SY-5: Clinical trial of bone regeneration for veterinary patients: The bone reconstructive surgery using Escherichia-coli induced rhBMP-2 for dog and catsYasuji HaradaLaboratory of veterinary surgery, Nippon Veterinary and Life Science University, Tokyo, Japan

65-SY-6: Guideline for securing the safety of regenerative medicine and cell therapy in dogs and catsKazuya EdamuraGuidline Working Group, the Japanese Society for Veterinary Regenerative Medicine, Japan

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64-SY Cardiovascular regenerative therapyChairs: Hsing-wen Sung, Jun Fujita

64-SY-1: Injectable Cell Delivery Constructs and Conductive Hydrogels for Myocardial Tissue EngineeringHsing-wen Sung，Chieh-Cheng Huang，Chun-Wen Hsiao，Wen-Yu Lee，Hung-Wen Tsai，Hao-Ji Wei，Yen ChangDepartment of Chemical Engineering and Institute of Biomedical Engineering, National Tsing Hua University, Hsinchu, Taiwan

64-SY-2: Miniature Heart with Pump FunctionTetsutaro Kikuchi，Hirotsugu Kubo，Katsuhisa Matsuura，Tatsuya ShimizuInstitute of Advanced Biomedical Engineering and Science, Tokyo Women's Medical University, Japan

64-SY-3: Synergy of ECM type and elasticity on the self-beating cardiomyocyte differentiation of iPS Tetsuji Yamaoka，Mitsuhi HirataDepartment of Biomedical Engineering, National Cerebral and Cardiovascular Center Research Institute, Japan

64-SY-4: The Effect of Mechanical Training on Human iPS cell-derived Cardiac Tissue Sheet StacksVictor Lopez Davila，Hidetoshi Masumoto，Jun K YamashitaDepartment of Cell Growth and Differentiation, Center for iPS Cell Research and Application, Kyoto University, Kyoto, Japan

64-SY-5: Heterotypic Effects within Cardiac Microtissue Environments on Human iPS-derived Cardiomyocyte Phenotype and FunctionTodd C McDevitt，Tracy A Hookway，Oriane B Matthys，Diwakar Turaga，Ana C SilvaGladstone Institutes / UCSF, USA

09:30 - 11:00

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★：Keynote



69-SY Technologies for Cell & Tissue OrientationChair: Alicia El Haj

69-SY-1: Electrical Stimulation to Improve Stem Cell OsteogenesisSarah Cartmell，Juan Shong Khaw，Nigel J CassidySchool of Materials, The University of Manchester, Manchester, UK

69-SY-2: Characterisation of RAFT-stabilised collagen gradients and their impact on neurite growth Celine Kayal，Dr Emad Moeendarbary，Dr Rebecca J. Shipley，Dr James B. PhillipsUCL Mechanical Engineering, London, UK / UCL Centre for Nerve Engineering, London, UK

69-SY-3: Engineered 3D Skeletal Muscle Tissues for In Vitro Metabolism StudiesXiomara Fernandez Garibay，Alejandro Hernández-Albors，Albert García Castaño，Ferran Velasco-Mallorquí，María Alejandra Ortega，Javier Ramón-AzcónBiosensors for Bioengineering group, Institute for Bioengineering of Catalonia (IBEC), The Barcelona Institute of Science and Technology, Barcelona, Spain

69-SY-4: Functionalization of a human skeletal muscle tissue construct using a fibrin-based gel for tissue modelingHironobu Takahashi，Tatsuya Shimizu，Masayuki Yamato，Teruo OkanoInstitute of Advanced Biomedical Engineering and Science, Tokyo Women's Medical University, Tokyo, Japan

69-SY-5: Engineering Magnetic, Patterned Human Heart Patches for Cardiac RegenerationLimor Zwi Dantsis，Daniel J. Stuckey，Camille A. Marijon ，Brian Wang，Cesare M.N. Terracciano，Molly M. StevensDepartment of Materials, Department of Bioengineering, and Institute of Biomedical Engineering, Imperial College London, London, UK

69-SY-6: A microscale biomimetic platform for generation and electro-mechanical stimulation of 3D cardiac constructsRoberta Visone，Giuseppe Talò，Paola Occhetta，Silvia Lopa，Alberto Redaelli，Matteo Moretti，Marco RasponiDepartment of Electronics, Information and Bioengineering, Politecnico di Milano, Milan, Italy

68-SY RNA interference to promote tissue regenerationChairs: Sing Yian Chew, Valerie Geoffroy

68-SY-1: Osteogenic Programming by Inhibiting Epigenetic SuppressionAndre van WijnenDepartment of Orthopedic Surgery & Biochemistry and Molecular Biology, Mayo Clinic, Rochester, Minnesota, USA

68-SY-2: Smart hydrogels for local and controlled delivery of RNAi molecules to cells for tissue regenerationEben AlsbergDepartment of Biomedical Engineering and Orthopaedic Surgery, Case Western Reserve University, Cleveland, OH, USA

68-SY-3: Sustained non-viral delivery of small non-coding RNAs to promote nerve regenerationShin Jia Chin，Jiah Shin Chin，Na Zhang，Ulla Milbreta，Coline Pinese，Hitomi Shirahama，Jun Quan Lin，Wutian Wu，Hang Liu，Wei JiangSchool of Chemical and Biomedical Engineering, Nanyang Technological University, Singapore / Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore

68-SY-4: Spatiotemporally Controlled CRISPR/Cas9 Gene EditingElena Moroz，Christopher L. Grigsby，Molly M. StevensDepartment of Bioengineering, Imperial College London, UK / Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Sweden

68-SY-5: Controlled Release System of Antisense Oligonucleotides from PEG-fibrinogen Hydrogels in the Treatment of Duchenne Muscular DystrophyShani Cohen，Claudia Fuoco，Ersiilia Fornetti，Cesare Gargioli，Dror Seliktar，Stefano TestaFaculty of Biomedical Engineering, Technion Israel institute of Technology, Haifa, Israel

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67-SY Platelet derivatives and platelet-derived biomaterials in TERMChairs: Manuela Gomes, Rui L. Reis

67-SY-1: Platelet derivatives as cell culture supplements and as triggers of endogenous regeneration mechanisms for tissue repairRanieri Cancedda，Maddalena MastrogiacomoBiorigen Srl, Genova, Italy

67-SY-2: Platelet lysate induces activation of chondroprogenitor cells in mature human articular cartilageChiara Gentili，Simonetta Carluccio，Daniela Martinelli，Rui Pereira，Elisabetta Palamà，Maddalena Mastrogiacomo，Ranieri CanceddaLaboratory of Regenerative Medicine, Dep. of Experimental Medicine, University of Genoa, Italy

67-SY-3: Platelet Lysate-laden Hyaluronic Acid/Cellulose Nanocrystals Hydrogels Display Chemotactic and Pro-angiogenic PropertiesPedro Babo，Cristiana R Silva，Maurizio Gulino，Rui M A Domingues，Rui L Reis，Manuela E Gomes3B’s Research Group – Biomaterials, Biodegradable and Biomimetics, Avepark – Parque de Ciência e Tecnologia, Zona Industrial da Gandra, Barco – Guimarães, Portugal / ICVS/3B’s – PT Government Associate Laboratory, Braga/Guimarães, Portugal

67-SY-4: Molecular Mechanisms of Platelet-Rich Plasma (PRP): Implications for Clinical UseLing He，Jeffrey A Ahn，Gregory Chotkowski，Qimei Gong，Jinxuan Zheng，Scott Rodeo，Jin Wen，Hanying Bai，Jasmine J Pei，Yoon Kun，Junqi LingCenter for Craniofacial Regeneration, Columbia University, USA / Guanghua School of Stomatology, Hospital of Stomatology, Sun Yat-sen University, Guangzhou, China

67-SY-5: The Effects of Platelet Lysate on Human Macrophages in in vitro Mono- or Co-Culture with hBMSCsTina Tylek，Tatjana Schilling，Katrin Schlegelmich，Franz Jakob，Jürgen GrollDepartment of Functional Materials in Medicine and Dentistry, University Hospital Wuerzburg, Germany

09:30 - 11:00

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★：Keynote



72-SY Recall the Regenerative Potential Through Robot Engineering and Mechanical StimulationChairs: Louis Yuge, Li Gang

72-SY-1: Novel Management of Larger Bone Defect: Combination of Biomaterials and Distraction Osteogensis TechniqueLi GangDepartment of Orthopaedics and Traumatology, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong

72-SY-2: Dawn of Cybernic Treatment -- Functional Regenerative Treatment by Cybernic System HALYoshiyuki SankaiCenter for Cybernics Research, University of Tsukuba/ImPACT Program, Japan Science & Technology Agency (JST) /CYBERDYNE, INC

72-SY-3: Study of human mesenchymal stem cell behaviors on isotropic gravity Mee-Hae Kim，Chaiyong Koaykul，Yumi Kawahara，Louis Yuge，Masahiro Kino-okaDepartment of Biotechnology, Graduate School of Engineering, Osaka, Japan

72-SY-4: Interactive effects of cell therapy and rehabilitation in brain injury model Takeshi Imura，Kei Nakagawa，Yumi Kawahara，Kaoru Kurisu，Louis YugeDivision of Bio-Environmental Adaptation Sciences, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan

72-SY-5: Endeavor of Regenerative Medicine Combined with Cellular Based Therapy Using Microgravity and Robotic RehabilitationLouis YugeDivision of Bio-Environmental Adaptation Sciences, Graduate School of Biomedical and Health / Space Bio-Laboratories Co., Ltd., Sciences, Hiroshima University, Hiroshima, Japan

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73-SY Regenerative medicine for muscular diseasesChairs: Hidetoshi Sakurai, Takahiko Sato

73-SY-1: Three-dimensional Human Pluripotent Stem Cell-derived Artificial Skeletal Muscles for Disease Modelling and Multilineage Tissue EngineeringFrancesco Saverio TedescoDepartment of Cell and Developmental Biology, University College London, London, UK

73-SY-2: Establishment of a long-term culture system for Muscle stem cellsShinichiro HayashiDepartment of Neuromuscular Research, National Institute of Neuroscience, NCNP, Tokyo, Japan

73-SY-3: Core transcription factors promote induction of functional Pax3-positive skeletal muscle stem cellsTakahiko Sato，Hidetoshi Sakurai，Chie SotozonoFujita Health University, Japan/ Kyoto Prefectural University of Medicine, Japan

73-SY-4: Cell Therapy for Muscular Dystrophy by Human IPS Cell-Derived Muscle Stem CellsHidetoshi Sakurai，Atsutoshi Tazumi，Satoru Takayama，Mingming Zhao，Nana Takenaka-Ninagawa，Makoto Ikeya，Akitsu Hotta，Takahiko Sato，Yuta ItoCenter for iPS Cell Research and Application (CiRA), Kyoto University, Japan

73-SY-5: Mesenchymal Stromal Cells Improve Regeneration of Severely Injured Muscles via Local Modulation of CD4+ and CD8+ T Cell LevelsSven Geissler，Taimoor Qazi，Manuela Hoffmann，Matthias Pumberger，Janosch Schoon，Tobias Winkler，Agnes Ellinghaus，Norma Schulz，Katharina Schmidt-Bleek，Carsten Perka，Georg Duda，Simon Reinke，Michael FuchsBerlin-Brandenburg Center for Regenerative Therapies, Charite Universitaetsmedizin Berlin, Berlin, Germany / Center for Musculoskeletal Surgery, Charite – Universitaetsmedizin Berlin, Berlin, Germany / Julius Wolff Institute, Charite – Universitaetsmedizin Berlin, Berlin, Germany

73-SY-6: A 3D Bioprinting of Biomimetic Human Skeletal Muscle Tissue Constructs for Restoration of Volumetric Muscle LossSang Jin Lee，Ji Hyun Kim，In Kap Ko，James J Yoo，Anthony AtalaWake Forest Institute for Regenerative Medicine, Wake Forest School of Medicine, USA

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71-SY Current update of tissue engineering and biomaterial for corneal diseases: what is the bottleneck for translational research?Chairs: Noriko Koizumi, Gilles Thuret

71-SY-1: Translational Research of Cultured Corneal Endothelial Cell Transplantation Naoki OkumuraDepartment of Biomedical Engineering, Doshisha University, Kyoto, Japan

71-SY-2: Femtosecond laser cut corneal stromal lamellae for the bioengineering of endothelial graftsGilles Thuret，Zhiguo He，Emmanuel Crouzet，Samy AL Bourgol，Pascal Herbepin，Chantal Perrache，Clotilde Jumelle，Gregory Egaud，Philippe GainLaboratory: Biology, imaging and engineering of the Corneal Grafts. BiiGC EA2521 University Jean Monnet, Faculty of Medicine, Saint-Etienne, France / Ophthalmology dpt, University Hospital, Saint-Etienne, France / Institut Universitaire de France, Paris, France / MANUTECH-Ultrafast Surfacing Design, Saint-Etienne, France

71-SY-3: Co-ordinated generation of multiple ocular cell lineages and fabrication of corneal epithelial cell sheets from human iPS cellsRyuhei HayashiDepartment of Stem Cells and Applied Medicine, Osaka University Graduate School of Medicine, Suita, Osaka, Japan / Department of Ophthalmology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan

71-SY-4: Acellular Porcine Cornea as a Replacement for Human Corneal TransplantationDar-Jen Hsieh，Fan-Wei Tseng，Yi-Hsung Huang，Ming-Lung YehACRO Biomedical Co., Ltd., Kaohsiung City, Taiwan

71-SY-5: Regulatory perspectives on developing investigational regenerative medical products in JapanMasakazu HirataRegulatory Science Center, Pharmaceuticals and Medical Devices Agency, Tokyo, Japan

13:20 - 14:50

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★：Keynote



76-SY Kidney and endocrine organsChairs: Kenji Osafune, Hidetaka Suga

76-SY-1: Differentiation of human iPSCs into kidney and pancreatic lineages towards regenerative therapyKenji OsafuneCenter for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, Japan

76-SY-2: Functional hypothalamus and pituitary induction in vitro from human pluripotent stem cellsHidetaka Suga，Chikafumi Ozone，Koichiro Ogawa，Takatoshi Kasai，Kazuki Mitsumoto, Hiroshi ArimaDepartment of Endocrinology and Diabetes, Nagoya University Graduate School of Medicine, Aichi, Japan

76-SY-3: Curvature Promotes Podocyte Differentiation in a Biomimetic Cell Culture PlatformAnastasia Korolj，Carol Laschinger，Christian James，Erding Hu，Robert Willette，Claire Velikonja，Nathaniel Smith，Samad Ahadian，Milica Radisic，Boyang ZhangDepartment of Chemical Engineering and Applied Chemistry, University of Toronto, Toronto, Canada / Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, Canada

76-SY-4: HIGH THROUGHPUT OPTIMISATION OF KIDNEY TISSUE PATTERNING FROM HUMAN PLURIPOTENT CELLS USING MICROBIOREACTOR ARRAYSJustin Cooper-White，Nick Glass，Minoru Takasako，Pei Xuan Er，Drew Titmarsh，Alejandro Hidalgo，Ernst Wolvetang，Melissa LittleThe University of Queensland

76-SY-5: Targeting renal fibrosis using self-assembled nanoparticles and injectable hydrogelsJoan Li，Justin Cooper-WhiteAustralian Institute for Bioengineering & Nanotechnology, University of Queensland, Australia

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75-SY Gene2Skin Twinning H2020 Project- Roadmap for advanced genetic engineering-based skin therapiesChairs: Rui L. Reis, Alexandra P. Marques

75-SY-1: Gene2Skin: Scaffold-based delivery of therapeutic genes for enhanced skin repairFergal O´Brien，Rosanne M Raftery，Ashang Luwang Laiva，Michael B KeoghTissue Engineering Research Group, Dept. of Anatomy, Royal College of Surgeons in Ireland (RCSI), Ireland / Advanced Materials and Biomedical Engineering Research (AMBER) Centre, RCSI, Ireland / Trinity Centre for Bioengineering, Trinity College Dublin, Ireland

75-SY-2: Gene2Skin: in vitro cues as tools to improve the performance of skin tissue engineering strategiesAlexandra P. Marques3B's Research Group, University of Minho, Portugal / ICVS/3B’s – PT Government Associate Laboratory, Portugal / The Discoveries Centre for Regenerative and Precision Medicine, Headquarters at University of Minho, Portugal

75-SY-3: Disclosing the crosstalk between human adipose stem cells and keratinocytes towards re-epithelializationMariana T. Cerqueira，Rogério P. Pirraco，Rui L. Reis，Alexandra P. Marques3B’s Research Group - Biomaterials, Biodegradables and Biomimetics, University of Minho, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, Barco, Guimarães, Portugal / ICVS/3B’s - PT Government Associate Laboratory, Braga/Guimarães, Portugal

75-SY-4: Tailoring bioink biofeatures to meet skin microenvironments specificitiesLucilia P da Silva，Guido Paulat，Manuela M. E. Lago，Carla M Abreu，Andreia F Carvalho，Rui L Reis，Alexandra P Marques3B’s Research Group – Biomaterials, Biodegradables and Biomimetics, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, University of Minho, Avepark Barco, Guimarães, Portugal / ICVS/3B’s – PT Government Associate Laboratory, Braga/Guimarães, Portugal

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74-SY Vascular Tissue EngineeringChairs: Deling Kong, Anthony Weiss

74-SY-1: To be announcedSimon HoerstrupUniversity of Zurich, Switzerland

74-SY-2: Bilayer Vascular Graft based on Electrospun Fibers and Yarns for Vascular Tissue RegenerationXiumei MoCollege of Chemistry, Chemical Engineering and Biotechnology, Donghua University, Shanghai, China

74-SY-3: Construction of intelligent antithrombotic small diameter tissue engineered blood vessel in vivo by utilization host responseChuhong Zhu，Wen Zeng，Da Huo，Yanzhao Li，Feila LiuDepartment of Anatomy, National & Regional Engineering Laboratory of Tissue Engineering, State and Local Joint Engineering Laboratory for Vascular Implants, Key Lab for Biomechanics and Tissue Engineering of Chongqing, State Key Laboratory of Trauma, burn and Combined injury, Third Military Medical University, Chongqing 400038, China

74-SY-4: Clinical Translation of Vascular Tissue Engineering in Pediatric Heart SurgeryToshiharu ShinokaDepartment of CT Surgery, Nationwide Children's Hospital, Columbus, Ohio, USA

74-SY-5: In vivo engineered extracellular matrix scaffolds with aligned microchannels enhanced tissue regeneration and functional integrationDeling Kong，Meifeng Zhu，Wen Li，Xianhao Dong，Kai Wang，Qiang ZhaoKey Laboratory of Bioactive Materials of Ministry of Education, College of Life Science, Nankai University, Tianjin, China

74-SY-6: Local Delivery of Cl-Amidine from Electrospun Polydioxanone Templates Regulates Neutrophil NETosisGary Lee Bowlin，Allison E. Fetz，Indira Neeli，Karyl K. Buddington，Robert W. Read，Matthew P. Smeltzer，Marko Z. RadicDepartment of Biomedical Engineering, University of Memphis, Memphis, TN, USA

13:20 - 14:50

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★：Keynote



79-SY Role of Stem Cell Research in Academia Chairs: Sherif Karam , Gilson Khang

79-SY-1: Modeling Gastric Stem Cell DifferntiationSherif Karam UAE University, UAE

79-SY-2: Bioactive Nanofibers Induce Neural Transdifferentiation of Human Bone Marrow Mesenchymal Stem Cells (BMSCs)Wei Ji，Zaida Álvarez，Alexandra N Edelbrock，Kohei Sato，Samuel I. StuppSimpson Querrey Institute for BioNanotechnology, Northwestern University, Chicago, Illinois, United States / Prometheus, Division of Skeletal Tissue Engineering, KU Leuven, Leuven, Belgium / Skeletal Biology and Engineering Research Center, Department of Development and Regeneration, KU Leuven, Leuven, Belgium

79-SY-3: Modulation of Non-Coding RNAs to Promote Osteogenic Differentiation of Mesenchymal Stromal/Stem CellsSusan Santos，Andreia Silva，Maria Ines Almeida，Daniel Vasconcelos，Catarina Almeida，Hugo Caires，Marta Pinto，George Calin，Susana Gomes Santos，Mario Adolfo Barbosai3S, INEB, Instituto de Investigacao e Inovacao em Saude, University of Porto, Porto Portugal

79-SY-4: Construction of Stem Cell-based Novel Multi-Functional Targeting Vehicle and Its Application in Ischemic Stroke TherapyJian-Qing Gao，Xin-Chi JiangInstitute of Pharmaceutics, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, Zhejiang, China / Dr. Li Dak Sum & Yip Yio Chin Center for Stem Cell and Regenerative Medicine, Zhejiang University, Hangzhou, Zhejiang, China

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78-SY Polymer, Biopolymer, and Matrix-Mediated Delivery of Cell Signaling ProteinsChairs: Kelly A. Burke, Whitney L. Stoppel

78-SY-1: Chemical Modifications of Silk Related to Cell and Tissue GuidanceDavid L. KaplanTufts University, USA

78-SY-2: Heparin increases retention of TGF-β2 and GDF5 on biphasic silk fibroin scaffolds for tendon-to-bone tissue engineeringElizabeth R. Balmayor，Sònia Font Tellado，Silvia Chiera，Walter Bonani，Claudio Migliaresi，Antonella Motta，Patrina Su Ping Poh，Martijn van GriensvenDepartment of Experimental Trauma Surgery, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany

78-SY-3: A Wearable Bioreactor for Enhancement of In Vivo Limb Regeneration using an Adult Murine Digit Amputation ModelAnne S Golding，Lorenzo Tozzi，Dana Cairns，Matthew Schwartz，Nirosha Murugan，Clifford Tabin，Michael Levin，David KaplanDepartment of Chemical and Biological Engineering, Tufts University, Medford, USA / Department of Biomedical Engineering, Tufts University, Medford, USA

78-SY-4: Tailoring bioactivity of silk-based biomaterials via delivering and functionalization strategies with fibrinogen/thrombin, plant lectins or lamininAndreas Herbert Teuschl，Christina MAP Schuh，Anna Maria Weihs，Olivier Guillaume，Xavier Monforte，Heinz Redl，David L. Kaplan，Dominik RünzlerDepartment of Biochemical Engineering, University of Applied Sciences Technikum Wien, Vienna, Austria / Austrian Cluster for Tissue Regeneration, Vienna, Austria

78-SY-5: Growth factor delivery from silk-extracellular matrix composite sponges for skeletal muscle maturationWhitney L Stoppel，Elizabeth C Bender，Schuyler Link，Jonathan M Grasman，Lauren D Black, III，David L KaplanDepartment of Chemical Engineering, University of Florida, Gainesville, FL / Department of Biomedical Engineering, Tufts University, Medford, MA, USA

78-SY-6: Potential of combined delivery of Riboflavin and Retinoic acid from silk fibroin matrix for corneal stroma regeneration Promita Bhattacharjee，Mark AhearneTrinity Centre for Bioengineering, Trinity Biomedical Sciences Institute, Trinity College Dublin, University of Dublin, Ireland / Department of Mechanical and Manufacturing Engineering, School of Engineering, Trinity College Dublin, University of Dublin, Ireland

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77-SY Injectable scaffoldsChairs: Wenxin Wang, Sigen A

77-SY-1: Induced migration of endothelial cells and BMSCs into hydrogels by chemoattractants secreted by pro-inflammatory macrophages in situChangyou Gao，Xuguang Li，Xingang ZuoDepartment of Polymer Science and Engineering, Zhejiang University, China

77-SY-2: Development of 3D Printed Biodegradable Polyurethane Nanohybrid Scaffold for Heart Valve RegenerationSalfarina Ezrina Mohmad Saberi，Adrian Magaz，Arnold Darbyshire，Brian Cousins，Wenhui SongCenter for Nanotechnology & Regenerative Medicine, UCL Division of Surgery & Interventional Science, University College London, UK

77-SY-3: Human Hair Proteins as Raw Materials for Tissue Engineering and Regenerative Medicine ApplicationsKee Woei NgSchool of Materials Science and Engineering, Nanyang Technological University, Singapore / Skin Research Institute of Singapore, Singapore / Environmental Chemistry and Materials Centre, Nanyang Environment & Water Research Institute, Singapore

77-SY-4: An Injectable Multi-Responsive Hydrogel as Self-Healable Tissue Adhesive Exhibiting On-demand Dissolution Capacity Sigen A，Qian Xu，Wenxin Wang，Hongyun TaiCharles Institute of Dermatology, School of Medicine, University College Dublin, Dublin, Ireland

13:20 - 14:50

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★：Keynote



83-SY Translation of novel developments in bone engineering ? where do we stand?Chairs: Martijn van Griensven, Elizabeth Rosado Balmayor

83-SY-1: RNA therapeutics for bone healing: Is there a translational potential for this new therapeutic platform?Elizabeth R. BalmayorDepartment of Experimental Trauma Surgery, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany / Musculoskeletal Gene Therapy Group, Rehabilitation Medicine Research Center, Mayo Clinic, Rochester, MN, USA

83-SY-2: Gene transfer approaches to improving bone healingRodolfo De la Vega Amador，John FisherDepartment of Physical Medicine & Rehabilitation, Mayo Clinic, Rochester, USA

83-SY-3: Spatially controlled rhBMP2 delivery at the periosteum enables robust bone regeneration at low dosesTeja Guda，Laura Gaviria，Sergio Alejandro Montelongo，Joseph Pearson，Joo OngDepartment of Biomedical Engineering, University of Texas at San Antonio, USA

83-SY-4: CXCR4 Antagonism Endogenously Mobilises Stem and Progenitor Cells and Rescues Non-union DevelopmentRichard Meeson，Anita Sanghani-Kerai，Melanie Coathup，Gordon BlunnInstitute of Orthopaedics, Division of Surgery & Interventional Science, University College London, UK

83-SY-5: Cartilage intermediate µTissue assemblies for healing of critical-sized long bone defectsGabriella Nilsson Hall，Luís Freitas Mendes，Liesbet Geris，Ioannis Papantoniou，Frank P LuytenPrometheus, Division of Skeletal Tissue Engineering, KU Leuven, Leuven, Belgium / Skeletal Biology and Engineering Research Center, KU Leuven, Leuven, Belgium

83-SY-6: GreenBone, a Rattan-derived Bone Graft Scaffold Regeneration Potential: an Experimental Model in SheepAnnapaola Parrilli，Francesca Salamanna，Milena Fini，Elisaveta Kon，Maurilio Marcacci，Simone Sprio，Anna Tampieri，Lorenzo PradellaPreclinical and Surgical Studies Laboratory, Rizzoli Orthopaedic Institute, Bologna, Italy / BITTA Laboratory, Rizzoli Orthopaedic Institute, Bologna, Italy

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82-SY Regenerative Medicine with Allogenic Mesenchymal Stem Cells - The Current Status and Future Prospective -Chairs: Shuji Terai, Detlef Schuppan

82-SY-1: Regenerative medicine with allogeneic mesenchymal stem cells ~the current status and future prospective~Shuji TeraiDivision of Gastroenterology and Hepatology, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan

82-SY-2: Building a new treatment strategy for severe heart failure using allogenic mesenchymal stem cellsShigeru Miyagawa，Yoshiki SawaThe Department of Cardiovascular Surgery, Osaka University Graduate School of Medicine, Japan

82-SY-3: Investigator initiated clinical trial for the novel peptide drug mobilizing mesenchymal stem cells from bone marrow to accelerate tissue regeneration Katsuto Tamai，Yasushi Kikuchi，Takashi Shimbo，Ichiro Katayama，Yasufumi KanedaDepartment of Stem Cell Therapy Science, Osaka University, Suita, Japan / Department of Dermatology, Osaka University, Suita, Japan

82-SY-4: Strategies to develop mesenchymal stromal cell productsHidenori NonakaRohto Pharmaceutical Co., Ltd.

82-SY-5: Antifibrotic Therapies to enhance liver regeneration and stem cell engraftmentDetlef SchuppanInstitute of Translational Immunology, University Medical Center, Mainz, Germany; Division of Gastroenterology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, USA

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81-SY Multi-Scale Approaches for Complex Tissue GenerationChairs: Bhushan Mahadik, Antonios Mikos

81-SY-1: 3D Printing in Engineered 3D Scaffolds for Regenerative MedicineQing Liu，Hugh Qinghong Zhao，Zhongyong FanBeijing Advanced Medical Technologies, Beijing / Certer for Biomaterials & Medical Device 3D Printing, Fudan Zhangjiang Institute / The Institute for Translational Nanomedicine, Shanghai East Hospital / The Institute for Biomedical Engineering & Nano Science, Tongji University School of Medicine, China

81-SY-2: 3D Printing for Engineering Complex TissuesBhushan MahadikFischell Department of Bioengineering, University of Maryland, College Park, MD, USA

81-SY-3: Multi-Scale Biofabrication Approaches for Osteo-Chondral Tissue RegenerationJos MaldaDepartment of Orthopaedics, University Medical Center Utrecht, Utrecht, The Netherlands / Department of Equine Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands / Regenerative Medicine Utrecht, The Netherlands

81-SY-4: 3D Bioprinting: Translational Pathway to Clinical ApplicationJames YooWake Forest Institute for Regenerative Medicine, USA

14:50 - 16:20

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★：Keynote



86-SY Innovative devices for the treatment of endocrine/metabolic diseasesChairs: Shoichiro Sumi, Farzaneh Moghtader

86-SY-1: Problems to be solved in islet transplantationShoichiro SumiInstitute for Life and Medical Sciences, Kyoto University, Kyoto, Japan

86-SY-2: Treatment of Type 1 Diabetes with Encapsulated Xenogeneic IsletsKai-Chiang Yang，Sin-Yu Yang，Goichi Yanai，Priyadarshini Canning，Shoichiro SumiSchool of Dental Technology, College of Oral Medicine, Taipei Medical University, Taipei, Taiwan / Laboratory of Organ and Tissue Reconstruction, Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto, Japan

86-SY-3: Alginate-poly-L-ornithine-alginate(APA), three layered microencapsulated neonatal porcine islets(NPIs) -Islet-derived damage-associated molecular pattern molecule(DAMPs) affects in immune regulation-Shohta KodamaDepartment of Regenerative Medicine & Transplantation, Faculty of Medicine, Fukuoka University, Fukuoka, Japan / Research institute for Regenerative Medicine, Fukuoka University, Fukuoka, Japan / Center for Regenerative Medicine, Fukuoka University Hospital, Fukuoka, Japan

86-SY-4: Hexanoyl- and acetyl-glycol chitosan derivatives for functional pancreatic islet cell spheroid for treating Type 1 DiabetesYoung-woo Park，Dong Yun LeeDepartment of bioengineering, Hanyang University, Seoul, Republic of Korea / BK21 PLUS Future Biopharmaceutical Human Resources Training and Research Team, Hanyang University, Seoul, Republic of Korea / Institute of Nano Science &Technology (INST), Hanyang University, Seoul, Korea

86-SY-5: Regeneration of Pancreatic Islets from Pluripotent Stem CellsSha Jin，Huanjing Bi，Kaiming YeBiomedical Engineering Department, Binghamton University, New York, USA

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85-SY Laser perforation and alternative strategies for matrix repopulationChairs: Sylvia Nürnberger, Susanne Wolbank

85-SY-1: Overcoming the challenges of recellularizing a decellularized cartilage matrixGerjo van Osch，Johannes Lehmann，Sylvia NuernbergerEramus MC, University Medical Center Rotterdam, the Netherlands

85-SY-2: Laser engraving matrix treatment for successful repopulation of decellularized tissuesSylvia Nurnberger，Cornelia Schneider ，Xavier Monforte Vila，Andreas Teuschl，Elisabeth Kostal，Johann Zehetner，Claudia Keibl，Heinz Redl，Susanne WolbankLudwig Boltzmann Institute for experimental and clinical traumatology, Vienna / Department of Orthopedics and Trauma-Surgery, Medical University of Vienna / Austrian Cluster for Tissue Regeneration, Vienna, Austria

85-SY-3: Generation and characterization of a tissue-engineered trachea substitute using human nasal chondrocytes and laser perforated devitalized tracheal cartilage tissueDenis Baranovskii，Jan Demner，Sylvia Nürnberger，Olivier Braissant，Michael Baumgartl，Heinz Redl，Andrea Barbero，Didier Lardinois，Ivan MartinDepartment of Thoracic Surgery, University Hospital of Basel, Basel, Switzerland

85-SY-4: The Holy Grail of heart valve tissue engineering: creation of an uniformly repopulated tissue of dense interstitial cells – is laser manipulation the solution?Payam Akhyari，Markus Schomaker，Andreas Weber，Mareike Barth，Alexander Hof，Silja Raschke，Karina Baier，Laura Nehrenheim，Jessica Isabel Selig，Heiko Meyer，Artur LichtenbergDepartment of Cardiovascular Surgery, Medical Faculty, Heinrich Heine University, Dusseldorf, Germany

85-SY-5: Decellularized and matured esophageal scaffold for circumferential esophagus replacement: proof of concept in a pig modelMarlene Durand，Guillaume Luc，Guillaume Charles，Caroline Gronnier，Magali Cabau，Charlotte Kalisky，Mallory Meulle，Reine Bareille，Samantha Roques，Lionel Couraud，Johanna Rannou，Laurence Bordenave，Denis ColletCHU Bordeaux, CIC1401, Bordeaux, France / Univ. Bordeaux, Bordeaux, France / Inserm, Bioingénierie tissulaire, U1026, Bordeaux, France

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84-SY New frontier strategies in the fabrication of vascularized tissuesChairs: Tim Woodfield, Jeroen Rouwkema

84-SY-1: Fabricated vascularized tissues with elastic proteinAnthony S. Weiss，Giselle C. Yeo，Suzanne M. MithieuxCharles Perkins Centre, University of Sydney, NSW, Australia

84-SY-2: Silk – from Textiles to MedicineDavid KaplanTufts University, USA

84-SY-3: Bioprinted capillary beds as universal building blocks for multiple organ-on-a-chip applicationsAndreas Blaeser，Viola Seidenberg，Christoph Melcher，Daniela F Duarte Campos，Marius Köpf，Jan Schöneberg，Horst FischerDepartment of Biohybrid and Medical Textiles (BioTex), AME-Helmholtz Institute for Biomedical Engineering, ITA-Institut fuer Textiltechnik, RWTH Aachen University, Aachen, Germany / Department of Dental Materials and Biomaterials Research, RWTH Aachen University Hospital, Aachen, Germany

84-SY-4: Biofabrication of 3D Convoluted In-hydrogel Vessel-like Microfluidic Channels via Digital Light Processing Bioprinting Riccardo Levato，Khoon Lim，Debby Gawlitta，Tim Woodfield，Jos MaldaDepartment of Orthopaedics, University Medical Center Utrecht, Utrecht, The Netherlands

14:50 - 16:20

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★：Keynote



89-SY ESAO@Termis 2018 joint Symposium of the Working Groups on Tissue engineering and Bioartificial OrgansChairs: Dimitrios Stamatialis, Cecile Legallais

89-SY-1: Application of bioartificial organs in toxicology studiesCecile Legallais，Eric LeclercUMR CNRS Biomechanics & Bioengineering, University of Technology; Compiegne, France / Inserm U1193, HepatoBiliary Center, Villejuif, France

89-SY-2: Membrane systems and devices for the biofabrication of microtissuesLoredana De Bartolo，Sabrina Morelli，Antonella Piscioneri，Simona Salerno，Chien-Chung Chen，CheeHo Chew，Lidietta Giorno，Enrico DrioliInstitute on Membrane Technology, National Research Council of Italy, Italy

89-SY-3: Development of membrane based bioartificial pancreas devicesDimitrios Stamatialis，Katarzyna Skrzypek，Milou Groot Nibbelink，Yazmin Brito Barrera，Thomas Groth，Marcel Karperien，Aart van Apeldoorn(Bio)artificial organs, TechMed institute, University of Twente, AE Enschede, The Netherlands

89-SY-4: Biomaterials combined with stem cells for bone and cartilage tissue engineering*Nuno M. Neves3B's Research Group/University of Minho, Portugal

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88-SY Regenerative Microenviroment Therapies in Ischemia OrgansChairs: Takayuki Asahara, Shengmin Zhang

88-SY-1: Regenerative Microenvironment Therapy for Ischemic OrgansTakayuki AsaharaRegenerative Medicine Science, Tokai University, Kanagawa, Japan

88-SY-2: Exosome therapy for regenerative microenvironmentTakahiro OchiyaDivision of Molecular and Cellular Medicine, National Cancer Center Research Institute, Tokyo, Japan

88-SY-3: To be announcedDouglas LosordoNorthwestern University, USA

88-SY-4: Long-Term Follow-Up of the Trial: Allogeneic Mesenchymal Stem Cells for the Critical Lower Limb Ischemia TherapyMikhail A. Konoplyannikov，Pavel Yu. Orekhov，Vladimir P. Baklaushev，Vladimir A. Kalsin，Anton V. Chupin，Aleksander V. AveryanovFederal Research Clinical Center of the Federal Medico-Biological Agency of Russia, Moscow, Russia / Institute for Regenerative Medicine, Sechenov University, Moscow, Russia

88-SY-5: 3D human adipose-derived stem cells spheroids for practical application on the therapeutic angiogenesis in clinical limb ischemiaSangheon Kim，Dokyun Kim，Seongja OhCenter for Biomaterials, KIST, Seoul, Korea / Devision of Bio-Med, UST-KIST school, Seoul, Korea

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87-SY Immunomodulation in orthopaedic and dental tissue engineeringChairs: Yin Xiao, Zetao Chen

87-SY-1: Modulation of the osteoimmune environment by biomaterials and bone growth factors in osteogenesisYin XiaoQueensland University of Technology, Australia

87-SY-2: Additively Manufactured Biphasic Construct Loaded with BMP-2 for Vertical Alveolar Bone RegenerationSaso Ivanovski，Cedryck Vaquette，Sudheesh Kumar，Siamak Saifzadeh，Dietmar HutmacherSchool of Dentistry, The University of Queensland, Australia

87-SY-3: Construction of smooth surfaces for enhanced hemocompatibility and endothelial cell monolayer formationDeling Kong，Xianhao Dong，Meifeng Zhu，Xingyu Yuan，Lina Wang，Zhihong Wang，Kai WangKey Laboratory of Bioactive Materials of Ministry of Education, College of Life Science, Nankai University, Tianjin, China / Institute of Biomedical Engineering, Chinese Academy of Medical Science, Tianjin, China

87-SY-4: Blood prefabricated HA/TCP induced ectopic vascularized bone via modulating the osteoimmune environment Zetao Chen，Yin XiaoSun Yat-sen University, China

14:50 - 16:20

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★：Keynote



93-SY Cell therapies for tendon repair ? Nature’s engineers doing their jobChairs: Manuela Gomes, Roger Smith

93-SY-1: Engineering physiologically relevant in vitro microenvironments for cell-based therapies Dimitrios I ZeugolisREMODEL, NUI Galway, Galway, Ireland

93-SY-2: The role of magnetic stimulus in cell-based tendon regenerative therapiesManuela Gomes3B’s Research Group – Biomaterials, Biodegradables and Biomimetics, University of Minho, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, AvePark – Parque de Ciência e Tecnologia, Zona Industrial da Gandra, Barco GMR, Portugal / ICVS/3B’s – PT Government Associate Laboratory, Braga/Guimarães, Portugal / The Discoveries Centre for Regenerative and Precision Medicine, Headquarters at University of Minho, Guimarães, Portugal

93-SY-3: Multifactorial approaches towards tenogenic phenotype maintenance, trans-differentiation and differentiationDimitrios I Zeugolis，Christina Ryan，Naledi Shologu，Diana Gaspar，Paedar Rooney，Manus BiggsSFI CÚRAM, NUI Galway, Galway, Ireland

93-SY-4: Effect of ACL and PCL derived soluble ECM for tenogenic differentiation of adipose derived stem cellRiccardo Gottardi，Shinsuke Kihara，Tomoya Iseki，Freddie H. Fu，Rocky S. TuanUniversity of Pittsburgh, USA / Fondazione Ri.MED, Italy

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92-SY Live-cell Bioprinting for Tissue EngineeringChairs: Hang Lin, Rocky S. Tuan

92-SY-1: Novel Biofunctional Inks for Stem Cell-Based Cartilage Tissue PrintingRocky S. Tuan，Hang LinCenter for Cellular and Molecular Engineering, University of Pittsburgh School of Medicine / Institute for Tissue Engineering and Regenerative Medicine, The Chinese University of Hong Kong, Hong Kong

92-SY-2: Multi-Scale Biofabrication Approaches for Osteo-Chondral Tissue RegenerationJos MaldaDepartment of Orthopaedics, University Medical Center Utrecht, Utrecht, The Netherlands / Department of Equine Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands / Regenerative Medicine Utrecht, The Netherlands

92-SY-3: Generation of Functional Tissues through Cell PrintingJames J YooWake Forest Institute for Regenerative Medicine, USA

92-SY-4: Rebuilding the Heart using FRESH 3D BioprintingAdam W. FeinbergCarnegie Mellon University, USA

92-SY-5: The efficacy of a scaffold-free Bio 3D conduit developed from dermal fibroblasts on peripheral nerve regeneration in a canine ulnar nerve injury modelSadaki Mitsuzawa，Ryosuke Ikeguchi，Tomoki Aoyama，Hisataka Takeuchi，Hirofumi Yurie，Hiroki Oda，Souichi Ohta，Manami Tsuji，Shizuka Akieda，Koichi Nakayama，Shuichi MatsudaDepartment of Orthopaedic Surgery, Kyoto University Graduate School of Medicine, Kyoto, Japan

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91-SY Progress in cell sheets therapy for various diseasesChairs: Goshi Shiota, Shigeru Miyagawa

91-SY-1: Building a new treatment strategy for severe heart failure using Cell sheet technologyShigeru Miyagawa，Yoshiki SawaThe Department of Cardiovascular Surgery, Osaka University Graduate School of Medicine, Japan

91-SY-2: Development of anti-fibrotic cell sheets engineered from mesenchymal stem cells for liver fibrosisNoriko Itaba，Goshi ShiotaDivision of Molecular and Genetic Medicine, Graduate School of Medicine, Tottori University, Tottori, Japan

91-SY-3: Development of cell sheet therapy for esophageal regenerationNobuo KanaiTokyo Metropolitan Geriatric Medical Center, Japan

91-SY-4: Transplantation of Autologous induced Pluripotent Stem Cell-Derived Retinal Pigment Epithelium Cell Sheets for Exudative Age Related Macular Degeneration: A Pilot Clinical StudyYasuhiko HiramiDepartment of Ophthalmology, Kobe City Eye Hospital, Kobe, Japan

16:50 - 18:20

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★：Keynote



96-SY Tissue engineering of human vocal fold repair and regenerationChairs: Luc Mongeau, Shigeru Hirano

96-SY-1: Overview of tissue engineering and regenerative medicine of the vocal foldShigeru HiranoDepartment of Otolaryngology, Kyoto Prefectural University of Medicine, Kyoto, Japan

96-SY-2: Developmental tissue engineering principles to generate vocal fold mucosa Susan L. Thibeault，Vlasta Lungova，Hailey Hirsch，Kari StaussDepartment of Surgery, University of Wisconsin Madison, USA

96-SY-3: Bioorthogonal Synthesis of Hydrogel Matrices for the Engineering of a Vocal Fold Tissue ModelXinqiao JiaDepartment of Materials Science & Engineering, University of Delaware, USA

96-SY-4: Computational Modeling of Vocal Fold Biomaterials Design and EvaluationNicole Yee-Key Li-JessenSchool of Communication Sciences and Disorders, McGill University, Montreal, Canada

96-SY-5: Fabrication of Vocal Fold Scaffolds with Tissue-like Collagen Alignment Using 3D BioprintingLuc Mongeau，Tao Jiang，Hossein Ravanbakhsh，Huijie Wang，Alexei Kazarine，Haoqing Liu，Joseph M Kinsella，Luc MongeauDepartment of Mechanical Engineering, McGill University, Montreal, Canada

96-SY-6: Swelling behavior of carbon nanotube-based composite hydrogels used as injectable biomaterial for vocal foldsHossein Ravanbakhsh，Guangyu Bao，Neda Latifi，Luc MongeauMechanical Engineering Department, McGill University, Montreal, Canada

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95-SY Bioengineering tools enabling the application of MSC as trophic mediators in challenging diseasesChairs: Chiara Tonda-Turo, Piergiorgio Gentile

95-SY-1: The Regulatory Function of Mesenchymal Stem Cells is Environment DependentMark Andrew BirchDepartment of Surgery, University of Cambridge, Cambridge, UK

95-SY-2: Injectable Mesenchymal Stem Cells Loading Hydrogel for Spinal Cord RegenerationChiara Tonda-Turo，Matilde Ghibaudi，Rossella Laurano，Alessandro Vercelli，Gianluca Ciardelli，Marina BoidoPolitecnico di Torino, Department of Mechanical and Aerospace Engineering, Politecnico of Torino, Torino, Italy

95-SY-3: Mechanisms of Angiogenesis in Bioprinted Endothelial/Stem Cell Cocultures for Vascularized Tissue-Engineered ConstructsSarah Van Belleghem，Tolulope Awosika，Max Jonah Lerman，Charlotte Piard，Navein Arumugasaamy，John Patrick FisherUniversity of Maryland College Park, USA

95-SY-4: Mimicking N-cadherin Interactions via Engineered Hydrogels Confers Growth Factor Sensitivity and Enhances Paracrine Activity of Mesenchymal Stromal Cells Taimoor H Qazi，Anne Seliger，Janosch Schoon，Michael Fuchs，Georg N Duda，David J Mooney，Sven GeisslerJulius Wolff Institute, Charité Universitätsmedizin Berlin, Berlin, Germany

95-SY-5: HUMANIZE MICE AS AN ACCURATE PRECLINICAL TOOL TO STUDY MESENCHYMAL STEM CELLS (MSC)-T CELL INTERACTION DURING WOUND HEALING CELL THERAPY Carmen Escobedo-Lucea，Andres Sanz-Garcia，Marjo YliperttulaUniversity of Helsinki/TWINS/ Wyss Institute Harvard, Finland/Japan/USA

95-SY-6: Microvesicles of adipose derived mesenchymal stem cell improve the survival of transplanted fat graftsShan Mou，Zhen xing Wang，Jia ming SunDepartment of Plastic Surgery,Union Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan, China

95-SY-7: Enhanced therapeutic properties of allogeneic adipose-derived mesenchymal stromal cells cultured in a serum-free mediumHidenori Nonaka，Yui Ueno，Shigeyuki Ota，Hiyo Kishida，Kumiko Nagaoka，Masashi Ito，Tetsumasa YamadaROHTO Pharmaceutical Co., Ltd., Japan

95-SY-8: Substrate Mediated Redox Signaling in Human Mesenchymal Stem Cells for Functional Tissue RepairChor Yong Tay，Haibo YangSchool of Materials Science and Engineering, Nanyang Technological University, Singapore / School of Biological Sciences, Nanyang Technological University, Singapore

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94-SY Mechanobiology and Force Sensing in Regenerative MedicineChairs: Heinz Redl, Giancarlo Forte

94-SY-1: YAP-TEAD as a key mechanosensing hub in cardiac tissue formation and disease Giancarlo ForteInternational Clinical Research Center (ICRC), St. Anne's University Hospital Brno (FNUSA), Brno, Czech Republic / Competence Center for Mechanobiology in Regenerative Medicine, INTERREG ATCZ133, Brno, Czech Republic / Department of Biomaterials Science, Institute of Dentistry, University of Turku, Finland

94-SY-2: Material-induced Senescence (MIS): Fluidity Induces Senescent Type Cell Death to Cancer Cells Mitsuhiro Ebara，Koichiro Uto，Sharmy S ManoInternational Center for Materials Nanoarchitectonics, National Institute for Materials Science, Japan

94-SY-3: YAP-Dependent Extracellular Matrix Remodeling directly influences Cell MechanicsJorge Oliver-De La Cruz，Ana Rubina Perestrelo，Jan Vrbský，Fabiana Martino，Stefania Pagliari，Vladimír Vinarský，Guido Caluori，Jan Přibyl，Petr Skládal，Giancarlo ForteInternational Clinical Research Center (ICRC), St. Anne's University Hospital Brno (FNUSA), Brno, Czech Republic / Competence Center for Mechanobiology in Regenerative Medicine, INTERREG ATCZ133, Brno, Czech Republic

94-SY-4: Tracking therapeutic shockwaves and their impact on regenerationPaul Slezak，Roland Rose，David Hercher，Anna Weihs，Christiane Fuchs，Heinz Redl，Rainer Mittermayr，Cyrill SlezakLudwig Boltzmann Institute for Experimental and Clinical Traumatology, Austria

94-SY-5: Cellular Mechanics of Tumour Microenvironment Cells on Micropatterned SurfacesNaoki Kawazoe，Xinlong Wang，Guoping ChenResearch Center for Functional Materials, National Institute for Materials Science, Ibaraki, Japan

94-SY-6: Shape-memory cell culture platforms for dynamic mechanobiologyKoichiro Uto，Cole A DeForest，Deok-Ho Kim，Mitsuhiro EbaraInternational Center for Young Scientists (ICYS), National Institute for Materials Science (NIMS), Ibaraki, Japan

16:50 - 18:20

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★：Keynote


Symposia / Oral Presentations | September 7 (Fri), 2018

99-O TERM for heart, blood vessel & lungChairs: Katsuhisa Matsuura，Michael E. Davis

99-O-1: Direct cell reprogramming as a new emerging strategy in cardiac regenerationValeria Chiono，Camilla Paoletti，Carla Divieto，Franca Di Meglio，Clotilde Castaldo，Daria NurzynskaDepartment of Mechanical and Aerospace Engineering - Politecnico di Torino, Turin, Italy

99-O-2: Human cardiac derived cells (CardAP cells) for the treatment of chronic myocardial diseases – from individualized autologous to universal allogeneic cell-based therapiesMarion Haag，Stephan Detert，Sophie Van Linthout，Kathleen Pappritz，Muhammad Elshafeey，Christien M. Beez，Falk Diedrichs，Martina Seifert，Christof Stamm，Carsten Tschoepe，Michael SittingerBerlin-Brandenburg Center for Regenerative Therapies, Charitè – Universitaetsmedizin Berlin, corporate member of Freie Universitaet Berlin, Humboldt-Universitaet zu Berlin, and Berlin Institute of Health, Berlin, Germany / Tissue Engineering Laboratory, Charité - Universitaetsmedizin Berlin, Germany

99-O-3: A novel cell alignment method of human induced pluripotent stem cell-derived cardiomyocyte by cell sheet extensionJun Homma，Shogo Shimizu，Hidekazu Sekine，Katsuhisa Matsuura，Tatsuya ShimizuInstitute of Advanced Biomedical Engineering and Science, Tokyo Women's Medical University, Tokyo, Japan

99-O-4: Influence of fiber orientation and fibronectin coating on cardiomyocyte organization in electrospun Polyactive scaffoldsRabeil Sakina，Aida Llucià-Valldeperas，Carlos Mota，Jos G Maessen，Sandro Gelsomino，Paul Wieringa，Lorenzo MoroniComplex Tissue Regeneration Department, MERLN Institute for Technology-Inspired Regenerative Medicine, Maastricht University, the Netherlands

99-O-5: Personalized micro-3D human heart tissues for orphan drug developmentTetsuro Wakatsuki，Neil Daily，Pinar Kemanli，Michael Greenberg，Jennifer StrandeInvivoSciences, Inc. Madison Wisconsin, USA

99-O-6: VEGF- and PDGF-BB-Decorated Fibrin Matrices ensure Persistent and Therapeutic Vascular GrowthAndrea Banfi，Veronica Sacchi，Rainer Mittermayr，Joachim Hartinger，Patrick Heimel，Mikaël M. Martino，Roberto Gianni-Barrera，Jeffrey A. Hubbell，Heinz RedlDepartments of Biomedicine and of Surgery, Basel University Hospital, Basel, Switzerland

99-O-7: A tissue chip model mimicking the right ventricular hypertrophy in pulmonary arterial hypertension Fakhrul Ahsan，Ali Keshavarz，Taslim Al-Hilal，Wei LiTexas Tech University Health Sciences Center, School of Pharmacy, Amarillo, Texas, USA

99-O-8: Transplantation study of human alveolar stem cells derived from iPS cellsYuki Yamamoto，Shimpei Gotoh，Satoshi Ikeo，Yohei Korogi，Naoyuki Sone，Koji Tamai，Satoshi Konishi，Toyohiro HiraiDepartment of Respiratory Medicine, Kyoto University, Japan

99-O-9: Precision Cut Lung Slices (PCLSs) as a model for testing lung gene therapiesGizem Osman，Sze Yan Chan，Amanda Tatler，James Edward DixonUniversity of Nottingham, Wolfson Centre for Stem Cells, Tissue Engineering, and Modelling (STEM), Centre of Biomolecular Sciences, School of Pharmacy; University of Nottingham, Nottingham, UK

98-SY Bringing Cell Therapy to Industrialized Processing for Burns and WoundsChairs: Lee Ann Applegate, Wassim Raffoul

98-SY-1: Bringing Cell Therapy to Industrialized Processing for Burns and WoundsLee Ann Applegate，Philippe Abdel-Sayed，Paris Jafari，Wassim RaffoulDepartment of Plastic, Reconstructive & Hand Surgery, Unit of Regenerative Therapy, University Hospital of Lausanne, Switzerland

98-SY-2: Successful transfer of GMP progenitor cells from the Swiss Transplantation Program to Asia for burns and woundsBin-Ru She，Geofrey De Visscher，Corinne Scaletta，Lee Ann ApplegateTranswell Biotech Co. Ltd, Hsinchu, Taiwan

98-SY-3: Tissue perfusion assessment of paediatric burns by Laser Doppler Imaging (LDI)Anthony de Buys Roessingh，Tessa Mermod，Lee Ann Applegate，Wassim Raffoul，Oumama El EzziPediatric surgery, Hospital University Center of Lausanne, Switzerland

98-SY-4: Development of an in vitro wound infection model to bridge laboratory to the clinicManuel R Gonzalez，Verena Ducret，Sara Leoni，Paris Jafari，Lee Ann Applegate，Wassim Raffoul，Yok-Ai Que，Karl PerronMicrobiology Unit, Department of Botany and Plant Biology, Sciences III, University of Geneva, Geneva, Switzerland

98-SY-5: Angiogenic effect of anti-microbial dendrimers in combination with Biological Burn-wound bandagesPhilippe Abdel Sayed，Paris Jafari，Thissa Siriwardena，Tamis Darbre，Jean-Louis Reymond，Karl Perron，Ariane Kaeppeli，Dominique P. Pioletti，Lee Ann ApplegateRegenerative Therapy Unit, Department of Musculoskeletal Medicine, Lausanne University Hospital, Lausanne, Switzerland

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97-SY Biomaterials for Modulating Vasculature: Therapeutic ApplicationsChairs: Eric Brey, Omid Veiseh

97-SY-1: Functional Engineered Microvessels in Degradable Synthetic Elastomeric ScaffoldsMeghan EE Wright，Azusa Maeda，Shu-Chi A Yeh，Ralph S DaCosta，Charles P Lin，J Paul SanterreInstitute of Biomaterials & Biomedical Engineering, University of Toronto, Toronto, Canada

97-SY-2: Effective vascularization and robust bone formation in osteogenic grafts requires VEGF dose controlNunzia Di Maggio，Andrea Grosso，Alexander Lunger，Maximilian Gerard Burger，Francesc Mai，Priscilla S Briquez，Jeffrey Alan Hubbel，Veronica Sacchi，Dirk Johannes Schaefer，Andrea BanfiCell & Gene Therapy Laboratory, Department of Biomedicine, University of Basel, Basel, Switzerland

97-SY-3: Bi-affinity Multilayer Modified Collagen Scaffolds for Long Term Controlled bFGF Release to Improve AngiogenesisYanyan Chen，Wangping Hao，Jie Han，Jianwu DaiKey Laboratory for Nano-Bio Interface Research Division of Nanobiomedicine, Suzhou Institute of Nano-Tech and Nano-Bionics (SINANO), Chinese Academy of Sciences, Suzhou, China

16:50 - 18:20

symposia | september 5 (wed), 2018 · susana g. santos，andreia m. silva，josé h. ... ，maria...

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