symprove. the probiotic market is worth $32 billion globally 60% of uk/irish households regularly...
TRANSCRIPT
SYMPROVE
The probiotic market is worth $32 billion globally
60% of UK/Irish households regularly purchase them
A wide variety of probiotics on the market that claim to work
The Probiotic Market
So, do they work?
Do they contain the claimed number of viable organisms stated on the label?
Do they possess the robustness to transit through the gut?
Scientists at University College London (UCL) independently conducted a study that compared leading probiotic brands to find out the truth.
Aim: To subject the products to three challenge tests to assess if the bacteria:
ARRIVED In a live state
SURVIVEDStomach acid transit
THRIVED In the target area of the gut
4
ARRIVEDOnly dairy-based (Actimel, Yakult) or water-based (Symprove) probiotics delivered 100% or more than the claimed content
Delivers at least 75% of the amount claimed
for the product
Symprove
Actimel
Yakult
Arrived
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SURVIVEDOnly two products survived stomach transit time (120 minutes), with one of these continuing to decline. nly one product seems stable
After exposure, are the surviving bacteria still concentrated enough?
Survived
VSL#3Symprove
TIME (h)
120100806040200
1000
800
600
400
200
0
P (
µW
)
SymproveDairyDairyDryBig Brand DryDry
Key:
Symprove survivability
A real time measurement of the heat (growth) signature of the bacteria colony.Independent research at University College London (preliminary research – not yet published)
Faster and stronger growth than all others
The only product to grow in a realistic time to give benefit
Even stronger if acid attrition in the stomach is considered
SymproveDairyDairyDryBig Brand DryDry
Key:
TIME (h)
120100806040200
P (
µW
)
1000
1200
800
600
400
200
0
Symprove survivability post pH shock
A real time measurement of the heat (growth) signature of the bacteria colony after exposure to gastric juices.Independent research at University College London (preliminary research – not yet published)
THRIVEDOnly three products showed signs of strong growth within 10 hours. Others showed very slow, or even no growth
ThrivedColony starts growing
strongly within 10 hours to hit the target
areas in the gut
VSL3
Actimel
Symprove
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To be successful probiotic product needs to beat all
three challenge tests
Safely arrive, survive stomach acids,
and thrive in the target area of the gut
Only one product met all three challenges - with several products failing all three
challenges
Summary
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Overall results
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Irritable Bowel Syndrome
1 in 5 households contain someone with IBS
Despite the high prevalence the condition is extremely poorly managed
Sufferers try an average of 5 products each month but around half are still left battling the symptoms long-term
+Probiotic efficacy
A probiotic product not only has to reach the gut, it also has to do something beneficial once it arrives
There is a rationale for the use of probiotics in reducing IBS symptoms but rigorous clinical testing has been lacking
The efficacy of Symprove has been confirmed in a randomised, double-blind, placebo-controlled study by King’s College Hospital
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+Study results
Significant improvement was achieved in 4 weeks Improvement continued through the full 12 weeks
Results show that this multi-strain probiotic is safe, well-tolerated and efficacious in improving overall symptom severity in patients with IBS
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+Study results
The significant change in pain score is important as pain is regarded as the key measure for patient health
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+Study results
Patients report an objectively measurable improvement in their satisfaction with their bowel habit (constipation and diarrhoea)
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INTRODUCING NEW SYMPROVE
• We know it works – KING’s• We know how it works – UCL• We know that 1 bottle doesn’t work• We know price is a barrier
What do we know?
Proudly shows that Symprove is all about the gut Clearly shows where it works
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Symprove New Brand World
Links to Arrive, Survive and Thrive Works on targeted A-S-T
areas of the gut
The new packaging is consumer driven and supports our science While it is keeping its
natural and safety heritage
Symprove 12 week commitment
• The consumer commits• Symprove commits• The consumer benefits
through:a. Great valueb. Encouragement to
compliance• The retailer benefits from:
a. A higher value saleb. Repeat visits and salesc. A higher rate of sale
per customerd. Increased loyalty
Recent press coverageMonday, 22 September 2014
Any questions….