synthesis, characterization and biological activities of substituted oxadiazole, triazole,...

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2005 Thiadiazole derivatives R 0300 Synthesis, Characterization and Biological Activities of Substituted Oxadiazole, Triazole, Thiadiazole and 4-Thiazolidinone Derivatives. — A variety of aminophe- nyl-substituted title heterocycles are synthesized via cyclization reactions of thiosemi- carbazide (IV) or its precursor (II). Various oxadiazole derivatives such as (XI) exhibit antiinflammatory activity while the majority of the other heterocycles show antibacte- rial activity. — (AMIR*, M.; KHAN, M. S. Y.; ZAMAN, M. S.; Indian J. Chem., Sect. B: Org. Chem. Incl. Med. Chem. 43 (2004) 10, 2189-2194; Dep. Pharm. Chem., Hamdard Univ., New Delhi 110 062, India; Eng.) — A. Forchert 03- 131

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Page 1: Synthesis, Characterization and Biological Activities of Substituted Oxadiazole, Triazole, Thiadiazole and 4-Thiazolidinone Derivatives

2005

Thiadiazole derivativesR 0300 Synthesis, Characterization and Biological Activities of Substituted Oxadiazole,

Triazole, Thiadiazole and 4-Thiazolidinone Derivatives. — A variety of aminophe-nyl-substituted title heterocycles are synthesized via cyclization reactions of thiosemi-carbazide (IV) or its precursor (II). Various oxadiazole derivatives such as (XI) exhibit antiinflammatory activity while the majority of the other heterocycles show antibacte-rial activity. — (AMIR*, M.; KHAN, M. S. Y.; ZAMAN, M. S.; Indian J. Chem., Sect. B: Org. Chem. Incl. Med. Chem. 43 (2004) 10, 2189-2194; Dep. Pharm. Chem., Hamdard Univ., New Delhi 110 062, India; Eng.) — A. Forchert

03- 131