system-level bioengineering of functionalized pha ...predoc.… · post- and pre-doctoral positions...
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POST- AND PRE-DOCTORAL POSITIONS are offered to carry out a competitive research project in the field of Systems Metabolic
Engineering under Synthetic Biology framework:
System-level bioengineering of functionalized PHA production in Pseudomonas putida
The research project funded under H2020 is aimed to develop highly efficient catalysts for overproduction of functionalized bioplatics using P. putida chassis
Dra. Auxiliadora Prieto (contact person) [email protected]://www.cib.csic.es/en/grupo.php?idgrupo=76Dr. Juan Nogales
Requirements: Postdoc position: PhD in Microbiology. High technical skills in Molecular Biology and Biochemistry. Excellent English (written and spoken) is required
PhD position: Highly motivated student with degree in Biotechnology, Pharmacy,Biochemistry, Biology or similar. Master in Microbiology or similar.
Key words: Systems Biology, Synthetic Biology, Systems Metabolic Engineering, Biomaterials, Bioplastics, Biosustainability
Related publication:Prieto et al., (2014). Environ Microbiol. DOI: 10.1111/1462-2920.12760
Malonyl-CoA
Malonyl-ACP
3-Ketoacyl-ACP Enoyl-ACP
Acyl-ACP
(R)-3-hydroxyacyl-ACP
Acetyl-CoA
Fatty acids
Non-Fatty acid
precursors
(S)-3-hydroxyacyl-CoA
3-Ketoacyl-CoAtrans 2-enoyl-CoA
Acyl-CoA
(R)-3-hydroxyacyl-CoA
PHA
(R)-3-hydroxycarboxylic acid
β-oxidationde novo FA
synthesis
PHA cycle
Acs1
FadD
FadE
FadB FadB
FadA
PhaC1 PhaZ
TCA
Biomass
AccABCDFabD
FabB/F
FabG FabA/Z
PhaJ
FabG
FabB
PhaG(R)-3-hydroxybutyryl-CoA
Acetoacetyl-CoA
PhbA
PhbB
PhbC
PHB
Doctoral thesis will be developed at the Polymer Biotechnology group under the supervision of: