MAY 2000 VOLUME 67 • NUMBER 5 • ISSN 0891-1150

T A B L E OF C O N T E N T S FROM THE EDITOR

Caveat tester The unintended consequences of scattershot testing.

J.D. C L O U G H

312

1-MINUTE CONSULT

How should a patient 315 wi th an isolated GGT elevation be evaluated? Given G G T ' s extremely low specificity, do not

get on a merry-go-round of testing when this liver enzyme is elevated.

W . D . C A R E Y

MEDICAL GRAND ROUNDS

Screening for renal artery stenosis: 318 Which patients? Which test? For a patient with persistently high blood pressure despite multiple medications, which screening test for renovascular hypertension is best?

D.G. V I D T

CURRENT DRUG THERAPY

Using viral load, CD4+ levels, and clinical response to guide antiviral therapy for HIV A summary of the most recent guidelines from the International A I D S Society.

L .H. C A L A B R E S E

REVIEW

321

Recognizing and managing depression 329 in w o m e n throughout the stages of life To treat depression in women effectively, one needs to appreciate how it is linked to the cycle of women's lives.

J . M . C A R A N D A N G , K. F R A N C 0 - B R 0 M S 0 N , AND S. K A M A R E I

CONTINUED ON PAGE 311

D E D I C A T E D T O L I F E L O N G L E A R N I N G

JOURNAL«* MEDICINE

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MAY 2000

UPCOMING FEATURES

• W h i c h pat ients t o screen fo r BRCA m u t a t i o n s

• Improv ing c o m m u n i c a t i o n a b o u t DNR orders

• H o w l o w should t h e LDL go? A d e b a t e

• N e w f ind ings in t rea t ing t h e acute respiratory distress s y n d r o m e

• Keep ing t h e very o ld hea l thy

• In h e a r t - h e a l t h y ea t ing , m o d e r a t i o n kills

• TEE: T h e n e w s tandard in aort ic i m a g i n g

• Effect ive t r e a t m e n t o f A l z h e i m e r disease

• T h e ALLHAT trial: A l p h a blockers a n d hear t fa i lure risk

CONTINUED FROM PACE 306

UPDATE ON ACUTE CORONARY SYNDROMES

'Rescue' angioplasty for fai led thrombolysis 341 Although data are few, a strategy of angioplasty-after-thrombolysis seems reasonable and beneficial.

D. M U K H E R J E E AND S.G. ELLIS

REVIEW

Infective endocarditis: 353 Prevention, diagnosis, t reatment , referral With proper diagnosis and treatment, the cure rate for this challenging condition is over 80%.

T.F. KEYS

CARING FOR OLDER PATIENTS

Rapid assessment of rehabil i tat ion options 361 for functional disability A simple, stepwise protocol to rapidly assess functional disabilities.

H. H O E N I G , D.R. GATER, AND J. G A L B R A I T H

CURRENT DRUG THERAPY

Appropr iate use of second-generation 372 antihistamines T h e newer antihistamines, with little or no effect on the central nervous system, have largely replaced older agents.

L .C. PI E N

DEPARTMENTS

CME Credit Test 383

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