TABLE: Small Bowel Capsule Endoscopy exams descriptions and comparative interpretation.

Subject ID #

SBCE descriptionChanges in GI segments, and aspect in

the second SBCEDay 2 Day 30 Stomach Small bowel

1 Duodenal erosions, moderate intra-luminal narrowing in the distal ileum (possible ileal web) Normal small bowel mucosa. Distal small bowel stricture. similar, normal Improved in duodenum, mild abnormality

2 Multiple superficial gastric antral,duodenal and jejunal erosions. , and large lymphangiectasia in mid-distal ileum.

Healed gastric erosions. Delayed gastric emptying of the capsule endoscope without visualization of the small bowel after 8 hours of recording.

Improved, mild abnormality NA

3 Gastric erosion with coffee ground stain, duodenitis and lymphangiectasia in the proximal and mid small bowel. phlebectasia in mid and distal small bowel.

Normal capsule endoscopy examination without evidence of gastroduodenal erosions or ulcers.

Improved, mild abnormality Improved in duodenum

5 Multiple red spots in the duodenal bulb, with a small patch of erythema in the terminal ileum. Multiple tiny red spots in the proximal duodenum and jejunum. similar, normal similar, normal

6 One or two erythematous strictures in jejunum. Two or three additional small shallow linear ulcerations of the small intestine. Delayed capsule passage.

Grossly normal gastric examination. A circular narrowing in jejunum, with some ulceration. Multiple small linear erosions. Possible capsule retention. similar, normal No change, significant

abnormalities

9 The capsule endoscopy is essentially normal, with a few incidental tiny red spots. Multiple tiny red spots in proximal small bowel. A linear ulceration and a small additional ulceration in the terminal ileum. similar, normal Worsened , significant

abnormality

10 Very mild gastritis. A small patch of erythema at the mid to distal small bowel. A focal erythema in the gastric antrum/distal body. Mid-to-distal jejunal ulceration. iIeal erosion and ulcerations.

similar, mild abnormality

Worsened, significant abnormality

11 Mild Gastritis. Mild duodenitis. Very minimal erythema in the terminal ileum. Stomach grossly unremarkable. Duodenum bulb erosion, multiple tiny red spots throughout the entire small bowel. Proximal colonic ulceration.

Improved, mild abnormality

similar, mild duodenal abnormality

12 Numerous, small, focal denuded mucosa in the duodenum and proximal jejunum. A piece of foreign matter was probably a pill or some form of undigested food.

Non-specific mucosal changes in the duodenum and proximal jejunum, with mild, patchy, duodenal mucosa, and also cracked earth appearance. Mild linear erosion in

the terminal ileum. similar, normal Slight worsening. Mild

abnormalities

13 One tiny red spot in the stomach. A couple of tiny red spots in the proximal small bowel. Two to three focal erosions and possible shallow ulcerations in the mid small bowel.

Focal antral erosions and erythema. These changes are non-specific for a mild case of gastritis. Essentially normal small bowel, with some distal debris obscuring a part of

the examination.

Minimal worsening, mild abnormality

Improved, mild abnormality

14 Mild antral gastritis. Phlebectasia in the mid small bowel. Large amount of debris in the mid-to-distal small bowel, obscuring a significant portion of the small bowel.

Normal gastric mucosa. A tiny red spot in the proximal small bowel. Phlebectasia in the distal small bowel. A small reddish streak in mid-to-distal small bowel. The exam is

essentially unremarkable.

Improved, mild abnormality similar, normal

16 Normal stomach. Poor study quality due to a large amount of luminal small bowel debris. Probable healed small ulcers/scars in mid jejunum. Tiny ulcer in the proximal ileum

Mild, diffuse, antral gastritis. Denuded mucosa, erosion, ulcers from proximal jejunum to distal ileum. Probable mild colonic inflammation

Slight worsening, mild abnormality

Slight worsening. Significant

abnormalities

17 Normal stomach. Very trivial findings of minimal erosion denuded mucosa and blunted villi in the small intestine. .

Normal stomach. Some non-specific villous changes in the jejunum, with 2 ulcers in the distal jejunum/proximal ileum where there may be post op changes. similar, normal

Slight worsening. Significant

abnormalities

18 Normal stomach. Multiple tiny red spots. Small erosion near the ligament of Treitz.

Irregular Z-line. Very mild gastritis. Mild scar tissue or stricturein the proximal-mid ileum. Two small patches of whitish discoloration in the proximal duodenum. This may be due to some non-specific mild injury of the mucosal area. Couple of tiny red spots

in esophagus.

Minimal worsening, mild abnormality

Uncertain of any changes, mild abnormalities

19

Very mild gastritis with lumpy bumpy gastric mucosa. A small focal area of the denuded mucosa within the proximal duodenum. Probable mild superficial erosion in the area of the

distal jejunum. A small area of either focal inflammation or AV malformation at the distal ileum.

Tiny nodular mucosal fold in the proximal stomach. Probable focal scar tissue in the proximal jejunum. One or two areas of either circumferential scar tissue or slight

narrowing in the ileum.

Improved, mild normality

Improved, mild abnormality

21 An essentially normal study. A rapid small bowel transit, with less than 1 hour of duration of small bowel recording. Overall, the entire study appeared to be grossly unremarkable. similar, normal similar, normal

23 Diffuse antral gastritis/mild. Tiny duodenal ulcer. Dark mucosa Small antral gastric erosion. Mild small bowel erosion/ulceration at proximal to mid jejunum. Dark ileal mucosa.

similar, mild abnormality

similar, non-specific findings

24 Mild gastritis. Erosion and ulceration in jejunum. Failed small bowel examination, unable to give impression on the small bowel condition. NA NA

Small Bowel Capsule Endoscopy exams were evaluated by a blind GI specialist with initial descriptive report. By the end of the study, reports were returned to the same specialist who gave his interpretation on the significant changes between exams by each GI segment (stomach, and small bowel).Abbreviations: ID, identification number; GI, gastrointestinal; SBCE, small bowel capsule endoscopy; and N/A not appropriate.